Base de dados : LILACS
Pesquisa : Meningite [Descritor de assunto] OR Mening$ [Palavras]
Referências encontradas : 4647 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 465 ir para página                         

  1 / 4647 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
experimentalDocumentos relacionados
Id: 756058
Autor: Azevedo, Maria Ermelinda Filgueiras de.
Título: Identificação de Enterococcus spp. e avaliação da ocorrência de genes de resistência à vancomicina em amostras de pacientes de hospitais de Manaus, AM / Identification of Enterococcus spp. and evalution of the occurrence of resistance genes to vancomycin in hospital patients samples of Manaus, AM.
Fonte: Botucatu; s.n; 2013. 109 p. ilus, tab.
Idioma: pt.
Tese: Apresentada a Universidade Estadual Paulista. Faculdade de Medicina de Botucatu para obtenção do grau de Doutor.
Resumo: Os Enterococcus spp habitam normalmente o trato gastrointestinal de seres humanos e de animais. Desde 1980, foram identificados como importantes agente de infecções hospitalares. As espécies E. faecalis e E. faecium são agentes de diversas infecções, como bacteriemia, sepse, endocardite, infecção do trato urinário, infecções de feridas e meningite. A resistência adquirida, mais predominantemente a penicilina/ampicilina, aminoglicosídeos (alto nível de resistência) e glicopeptídeos são relatados em um número crescente de isolados e o espectro terapêutico nestes casos é limitado. A principal preocupação é que os genes que codificam a resistência para todos esses antibióticos poderiam ser transferidos para outros enterococos ou mesmo para muitos outros patógenos virulentos. A resistência adquirida aos glicopeptídeos é mediada por vários mecanismos (tipos VanA/B/D/E/G/L), sendo que os genótipos VanA e VanB são transferíveis. Fatores relacionados com o hospedeiro, com o hospital, procedimentos invasivos, meio ambiente, e o uso de antibióticos podem aumentar o risco de colonização ou infecção com VRE. Este estudo visa investigar a ocorrência destes microrganismos, em pacientes de hospitais de Manaus - Amazonas, identificando a distribuição das espécies e o perfil de resistência aos antimicrobianos e dos genes de resistência a vancomicina envolvidos. Foram analisados 38 isolados de Enterococcus spp. provenientes de pacientes internados ou de atendimento ambulatorial no período de outubro de 2011 a setembro de 2012. Foram confirmados 29 isolados de E. faecalis e 8 de E. faecium por testes bioquímicos convencionais, pela metodologia automatizada e por Reação da Polimerase em Cadeia (PCR)...(AU)

The Enterococcus spp. normally inhabit the gastrointestinal tract of humans and animals. Since 1980, have been identified as a major cause of nosocomial infections. The species E. faecalis and E. faecium are agents of various infections, such as bacteremia, sepsis, endocarditis, urinary tract infections, wound infections and meningitis. Acquired resistance, most predominantly penicillin / ampicillin, aminoglycosides (high-level resistance) and glycopeptides are reported in an increasing number of isolates and therapeutic spectrum in these cases is limited. The main concern is that the genes which encode resistance to these antibiotics could all be transferred to other Enterococci or for many other virulent pathogens. Acquired resistance to glycopeptides is mediated by several mechanisms (types VanA/B/D/E/G/L), with VanA and VanB genotypes are transferable. Factors related to the host, with the hospital, invasive procedures, environment, and the use of antibiotics may increase the risk of colonization or infection with VRE. This study aims to investigate the occurrence of these microorganisms in hospital patients of Manaus - Amazonas, identifying species distribution and antimicrobial resistance profile and vancomycin resistance genes involved. We analyzed 38 Enterococcus spp. from inpatient or outpatient care from October 2011 to September 2012. 29 isolates E. faecalis and 8 E. faecium were confirmed by conventional biochemical tests, the automated methodology and Polymerase Chain Reaction (PCR). An isolate of Enterococcus spp. was identified by automated equipment as E. casseliflavus, identification was not confirmed by PCR. The evaluation of the antimicrobial susceptibility profiles commonly used in clinical practice were performed by disk diffusion methods and automated...(AU)
Descritores: Resistência Microbiana a Medicamentos
Reação em Cadeia da Polimerase/métodos
Infecção Hospitalar/diagnóstico
Infecção Hospitalar/microbiologia
Enterococcus
Resistência a Vancomicina
Limites: Humanos
Masculino
Feminino
Responsável: BR33.1 - Divisão de Biblioteca e Documentação


  2 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
(texto :
EN)
experimentalDocumentos relacionados
Id: 755809 LILACS-Express
Autor: Matter, Letícia B.; Spricigo, Denis A.; Tasca, Caiane; de Vargas, Agueda C..
Título: Invasin gimB found in a bovine intestinal Escherichia coli with an adherent and invasive profile
Fonte: Braz. j. microbiol;46(3):878-878, July-Sept. 2015. tab, ilus.
Idioma: en.
Projeto: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). 23038007126201144.
Resumo:

The invasin gimB (genetic island associated with human newborn meningitis) is usually found in ExPEC (Extraintestinal Pathogenic Escherichia coli) such as UPEC (uropathogenic E. coli), NMEC (neonatal meningitis E. coli) and APEC (avian pathogenic E. coli). In NMEC, gimB is associated with the invasion process of the host cells. Due to the importance of E. coli as a zoonotic agent and the scarce information about the frequency of gimB-carrying strains in different animal species, the aim of this study was to investigate the presence of gimB in isolates from bovine, swine, canine and feline clinical samples. PCR was conducted on 196 isolates and the identity of the amplicons was confirmed by sequencing. Of the samples tested, only E. coli SB278/94 from a bovine specimen was positive (1/47) for gimB, which represents 2.1% of the bovine isolates. The ability of SB278/94 to adhere to and invade eukaryotic cells was confirmed by adherence and gentamicin-protection assays using HeLa cells. This is the first study that investigates for gimB in bovine, canine and feline E. coli isolates and shows E. coli from the intestinal-bovine samples harboring gimB.

.(AU)
Responsável: BR1.1 - BIREME


  3 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
(texto :
EN)
experimentalDocumentos relacionados
Id: 755770 LILACS-Express
Autor: Ramos, Leonor; Coutinho, Ines; Cardoso, José Carlos; Garcia, Helena; Cordeiro, Margarida Robalo.
Título: Frontal cutaneous meningioma - Case report
Fonte: An. bras. dermatol;90(3,supl.1):133-133, May-June 2015. ilus.
Idioma: en.
Resumo: Abstract

Cutaneous meningiomas are rare tumors most commonly located on the scalp. We report the case of a 55-year-old male who presented with a 2x3 cm tumoral lesion on the forehead. The lesion was hard, adherent and covered by normal skin. Incisional biopsy revelead a proliferation of monomorphic round cells, organized in nests and focally forming pseudovascular spaces. Immunohistochemical study revealed positivity for epithelial antigen membrane and vimentin. Vascular markers, cytokeratins and S100 protein were negative. A brain CT scan did not show any evidence of intracranial meningioma. The authors describe the case of a cutaneous frontal meningioma in probable relation with previous cranioencephalic trauma.

.(AU)
Responsável: BR1.1 - BIREME


  4 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 755635 LILACS-Express
Autor: Montoya, L. M; Ocampo, P. E; Sousa Rocha, N; Pedraza, F. J.
Título: ENFERMEDAD NEUROLÓGICA BOVINA CON DIAGNÓSTICO NO CONCLUSIVO EN LA REGIÓN NORTE DE COLOMBIA. ANALISIS HISTOLÓGICO E INMUNOHISTOQUÍMICO / NEUROLOGIOAL DISEASES IN CATTLE WITH NON-CONCLUSIVE DIAGNOSTIC IN THE COLOMBIA NORTHERN REGION. HISTOLOGICAL AND INMUNOHISTOCHEMICAL ANALYSES
Fonte: Rev. med. vet. zoot;62(1):37-49, ene.-abr. 2015. ilus, tab.
Idioma: es.
Resumo: La enfermedad neurológica bovina genera altas pérdidas económicas en las ganaderías y algunos de sus agentes etiológicos son zoonóticos, hechos que hacen prioritario su estudio. El objetivo del trabajo fue identificar antígenos del virus de la rabia y del herpes virus bovino-5 (BoHV-5) en muestras de encéfalos de bovinos archivados como casos de enfermedad neurológica con diagnóstico no conclusivo. Se seleccionaron 10 muestras del laboratorio del Instituto Colombiano Agropecuario -ICA- de Montería. Los tejidos fueron analizados mediante histopatología e inmunohistoquímica; para esta última técnica fueron utilizados tres anticuerpos: dos contra antígenos del virus de la rabia a una dilución de 1:200 y uno contra BoHV-5 a una dilución de 1:100. Histológicamente en nueve casos se observaron lesiones que variaron de tipo y severidad; la identificación de antígenos del virus de la rabia se demostró en 20% (2/10) de los casos y en ningún caso se demostró la presencia BoHV-5. Se discute sobre los resultados histopatológicos e inmunohistoquímicos y se concluye la importancia de asociar los hallazgos de las dos técnicas para establecer la etiología de la enfermedad neurológica, especialmente en casos con diagnóstico inconcluso.(AU)

Bovine neurological disease generates high economic losses in herds and some of its etiological agents are zoonotic, situations that make priority their study. The aim of this study was to identify antigens rabies virus and bovine herpesvirus-5 (BoHV-5) in cattle brain samples archived as cases of neurological disease with no conclusive diagnosis. 10 samples were selected from laboratory of the Colombian Agricultural Institute -ICA- at Monteria. Tissues were analyzed by histopathology and immunohistochemistry techniques. For immunohistochemical analysis, three antibodies were used: two against antigens of rabies virus at a dilution of 1:200, and one against antigens of BoHV-5 at a dilution of 1:100. Histologically lesions i nine cases lesions that varied in type and severity were observed; antigens detection of rabies virus could be demonstrated by immunohistochemistry in 20% (2/10) of cases and could not be demonstrated in any case the presence BoHV-5. We discuss on the histopathological and immunohistochemical finding, it is concluded on the importance of perform association of the two techniques to assist the establishing of the neurological disease etiology, especially in case without diagnostic.(AU)
Responsável: CO332 - Facultad de Medicina


  5 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Cendes, Fernando
Texto completo
experimentalDocumentos relacionados
Id: 754459 LILACS-Express
Autor: Pereira, Amanda Régio; Conz, Livia; Belfiore, Elio Barbosa; Moraes Neto, Jarbas Emílio de; Tedeschi, Helder; Morita, Marcia Elisabete; Cendes, Fernando; Yasuda, Clarissa Lin Yasuda.
Título: Contralateral hippocampal volume influences surgical outcome in patients with MTLE and similar degree of ipsilateral hippocampal atrophy / O volume hipocampal contralatral influencia o desfecho cirúrgico de pacientes com ELTM e grau semelhante de atrofia hipocampal ipsilateral
Fonte: J. epilepsy clin. neurophysiol;20(2), june 2014. tab, ilus.
Idioma: pt.
Resumo: Objective: to investigate the relationship between hippocampal atrophy (HA) and surgical outcome in patients with mesial temporal lobe epilepsy (MTLE). Methodology: we compared 34 patients free of seizure (GroupA) with 33 patients with persistent seizures after surgery (GroupB). All had preoperative diagnosis of unilateral MTLE by EEG and MRI evidence of unilateral hippocampal sclerosis (HS) by visual analysis. We performed hippocampal volumetry using high resolution T1 MRI (1mm) in all patients and in 30 healthy controls. Results: Z-score (Mean±SD) of affected hippocampus was -2.58±1.29 in GroupA and -2.57±1.47 in Group-B (p=0.98). The Z-Score of contralateral hippocampus was significantly lower in GroupB, compared to GroupA (p=0.038). Grouping all patients, smaller hippocampal volumes in the affected side were associated with history of meningitis (p=0.049), febrile seizures (p=0.049) and absence of family history of epilepsy (p=0.049). Conclusions: Ipsilateral HA was more severe in patients who had febrile seizures and meningitis, and in those without family history of epilepsy, supporting the notion that in the absence of genetic predisposition, more severe cerebral insult is necessary to induce epileptogenesis. Less favorable surgery outcome for unilateral MTLE was associated with smaller hippocampal volumes contralateral to the operated side, suggesting that surgery is less effective when bilateral damage exists, even when it is not detectable by visual MRI analysis.(AU)

Objetivo: investigar a relação entre atrofia hipocampal (AH) e resultado cirúrgico de pacientes com epilepsia de lobo temporal mesial (ELTM). Methodology: comparamos 34 pacientes livres de crises (grupoA) com 33 pacientes que permaneceram com crises após cirurgia (GrupoB). Todos apresentavam o diagnóstico pré-operatório de ELTM unilateral por EEG e RM com sinais de atrofia hipocampal (AH) unilateral na análise visual. Realizamos volumetria do hipocampo utilizando imagens T1 de RM de alta resolução (1mm) em todos os pacientes e em 30 controles sadios. Resultados: o Z-score (Média±DP) dos hipocampos afetados foi -2.58±1.29 no GrupoA e -2.57±1.47 no GrupoB (p=0.98). O Z-score dos hipocampos contralaterais foi significativamente menor no grupoB comparado ao grupoA (p=0.038). Agrupando todos os pacientes, volumes hipocampais menores no lado afetado foram associados à história de meningite (p=0.049), crises febris (p=0.049) e ausência de história familiar de epilepsia (p=0.049). Conclusão: AH ipsilateral foi mais acentuada em pacientes com antecedente de crises febris e meningite, e naqueles sem história familiar de epilepsia, reforçando a ideia de que na ausência de predisposição genética, um maior insulto cerebral seria necessário para induzir epileptogenesis. Um resultado cirúrgico menos favorável na cirurgia para ELTM unilateral foi associado a menores volumes hipocampais no lado contralateral ao lado operado, sugerindo que a cirurgia é menos efetiva quando há dano bilateral, mesmo quando não detectado por analise visual.(AU)
Responsável: BR1.1 - BIREME


  6 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Uruguai
(texto :
ES)
experimentalDocumentos relacionados
Id: 754245 LILACS-Express
Autor: Cedrés, Alejandra; Ferreira, Ma. Inés; Costa, Nadia; León, Virginia; Giachetto, Gustavo; Prego, Javier.
Título: Cumplimiento y resultados de la aplicación del protocolo de abordaje de la fiebre sin foco en lactantes de 29 a 90 días en el Departamento de Emergencia Pediátrica del Centro Hospitalario Pereira Rossell / Compliance and results of applying a protocol for treatment of fever without a source in infants of 29-90 days of age at the Pediatrics Emergency Unit of the Pereira Rossell Hospital Center
Fonte: Arch. pediatr. Urug;86(2):98-105, jun. 2015. ilus, tab.
Idioma: es.
Resumo: Resumen Introducción: el abordaje diagnóstico y terapéutico de niños menores de 36 meses con fiebre sin foco (FSF) ha sido motivo de controversias, particularmente en el grupo 29 a 90 días de vida. Objetivos: evaluar el cumplimiento y describir los resultados del nuevo protocolo de abordaje diagnóstico y terapéutico en los niños de 29 a 90 días de vida que consultan con FSF en DEP-CHPR. Material y métodos: se realizó un estudio transversal, descriptivo retrospectivo, en el que se incluyeron los niños entre 29 y 90 días que consultan con FSF en el DEP-CHPR, entre el 1 de octubre de 2012 y el 30 de setiembre de 2013. Resultados: en el período analizado hubo 134 consultas de niños entre 29 a 90 días de vida por FSF. Cumplieron la pauta 99 (74%). Los diagnósticos al egreso fueron: fiebre sin foco evidente 82 (61%), infección respiratoria aguda viral 23 (17%), meningitis viral y/o encefalitis 11 (8%), infección urinaria 8 (6%), gastroenteritis 4 (3%), meningoencefalitis aséptica 2 (1,5%), otitis media 2 (1,5%), meningoencefalitis aguda supurada 1 (0,75%), exantema viral 1 (0,75%). En los pacientes que presentaron infecciones graves se cumplió la pauta en 20 de 22 pacientes (90%). La principal causa de no cumplimiento fue no realizar los estudios según pauta en 20 (57%). Conclusiones: se detectó un porcentaje aceptable de cumplimiento del nuevo protocolo, la no adherencia estuvo dada fundamentalmente en la no realización de los estudios pautados. El rendimiento en la detección de EBI, infecciones virales graves y bacteriemia fue bueno.(AU)

Introduction: diagnostic and therapeutic approach of children younger than 36 months with fever without a source has been controversial, particularly in those between 29 and 90 days of age who consult at the Pediatrics Emergency Unit Emergency Unit of the Pereira Rossell Hospital Center. Method: a transversal, descriptive, retrospective study was conducted, including children between 29 and 90 days who consulted for fever without a source at the Pediatrics Emergency Unit Emergency Unit of the Pereira Rossell Hospital Center between August 1, 2012 and September 30, 2013. Results: during the time of the study, there were 134 children between 29 and 90 days who consulted for fever without a source. Ninety nine of them (47%) meet the requirements. Diagnosis upon release were: fever without evidence of focus 82 (61%), acute viral respiratory infection 23 (17%), viral meningitis and/or encephalitis 11 (8%), urinary tract infection 8 (6%), gastroenteritis 4 (3%), aseptic meningoencephalitis 2 (1.5%), otitis media 2 (1.5%), acute suppurative meningoencephalitis 1 )0.75%), viral exanthema 1 (0.75). When patients presented severe infections the recommendations were followed in 20 out of 22 patients (90%). The main cause for non-fulfilment was failing to ask for exams according to recommendations in 20 (57%).(AU)
Responsável: UY1.1 - BINAME - Biblioteca Nacional de Medicina


  7 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Uruguai
(texto :
ES)
experimentalDocumentos relacionados
Id: 754176 LILACS-Express
Autor: Jaume, Alejandra; Salle, Federico; Devita, Andrea; Martínez, Fernando; Sgarbi, Nicolás.
Título: Fístula de líquido cefalorraquídeo postraumática: propuesta de algoritmo diagnóstico y terapéutico / Post-traumatic cerebrospinal fluid fistula: proposal of diagnostic and therapeutic algorithm
Fonte: Arch. med. interna (Montevideo);37(1):47-52, mar. 2015. ilus.
Idioma: es.
Resumo: Introducción: la fístula de líquido céfalorraquídeo (LCR) se define como la salida anormal de líquido desde el cráneo al exterior a través de una brecha osteomeníngea, constituyendo una puerta de entrada de gérmenes al endocráneo y sus espacios con potencial riesgo infeccioso y en ocasiones vital. Es una patología relativamente frecuente, la cual clásicamente se divide en fístulas traumáticas y no traumáticas, siendo un gran desafío para el neurocirujano su resolución. Objetivo: presentar el primer caso de fístula de LCR postraumática en Uruguay, estudiado con cisterno-RNM, como método diagnostico. Caso clínico: se presenta el caso clínico de un paciente asistido en el Hospital de Clínicas. A través de este caso clínico ilustrativo, se busca realizar una puesta al día con respecto a los principales puntos de controversia, en vistas a plantear un algoritmo diagnostico y terapéutico. Discusión: encontramos como principales puntos de controversia: el comienzo de tratamiento (tto) antibiótico (ATB) profiláctico una vez realizado el diagnostico; que estudios paraclínicos imagenológicos son necesarios para el diagnostico, y, el tipo de tratamiento indicado. Conclusiones: de la bibliografía analizada, podemos concluir, que para un correcto diagnostico, se deben solicitar de rutina TC y RMN, y, si hay dudas: cisterno-RNM, endoscopía, o cisterno-TC. En cuanto al algoritmo terapéutico, concluimos que se debe realizar tratamiento conservador, con tratamiento medico por dos a cuatro semanas, y, si persiste fístula se debe indicar tratamiento quirúrgico. El tto. ATB es una opción y no una recomendación.(AU)

Introduction: the cerebrospinal fluid (CSF) fistula is defined as the abnormal leak of fluid from the skull to outside the body through an osteomeningeal gap, which allows the passage of organisms to the intra-cranial space, with the risk of infection, potentially life-threatening. Divided as traumatic and non-traumatic, the condition is relatively common, and poses great challenges to neurosurgeons. Objective: to present the first case of post-traumatic CSF fistula in Uruguay, assessed with cistern MRI with diagnostic purposes. Case report: the case described is that of a patient that received treatment at the University Hospital (Hospital de Clínicas). The case is used to illustrate the condition and review the latest controversial issues involved in the algorithms for the diagnosis and therapy of the condition. Discussion: the main controversial issues found included the following: when to start prophylactic antibiotic (ATB) therapy following diagnosis; imaging tests requested for diagnosis, and type of therapy prescribed. Conclusions: the review of literature leads us to conclude that a correct diagnosis requires the routine use of CT and MRI; if doubts persist, cistern MRI, endoscopy, or cistern CT are indicated. With regards the therapeutic algorithm, we conclude that therapy should be conservative, applying medical therapy for two to four weeks; surgery will be prescribed if the fistula persists after that. Antibiotic therapy is an option and not a recommendation.(AU)
Responsável: UY1.1 - BINAME - Biblioteca Nacional de Medicina


  8 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Uruguai
(texto :
ES)
experimentalDocumentos relacionados
Id: 754174 LILACS-Express
Autor: Aramburú, J. Ignacio; Verdier, Verónica; Jaume, Alejandra; Aboal, Carlos.
Título: Hemangiopericitoma intracraneano: Reporte de un caso y revisión del tema / Intracranial Haemangiopericytoma: Case report and literature review
Fonte: Arch. med. interna (Montevideo);37(1):36-42, mar. 2015. ilus.
Idioma: es.
Resumo: INTRODUCCIÓN: el Hemangiopericitoma (HPC) es un tumor hipervascular infrecuente que constituye menos del 1% de todos los tumores del Sistema Nervioso Central (SNC) y aproximadamente el 3% de los tumores vinculados a las meninges. Son tumores agresivos que requieren un tratamiento enérgico mediante cirugía y radioterapia, y a pesar del mismo, generalmente son tumores recidivantes, pudiendo generar metástasis a distancia. OBJETIVOS: comunicar el primer caso en que se hace diagnóstico con un panel inmunohistoquímico completo de HPC en Uruguay, y a partir del mismo, se realiza una revisión bibliográfica. MATERIALES Y MÉTODO: en primer lugar se presenta un caso clínico de un paciente que fue asistido en el Hospital de Clínicas. Mediante estudios de imagen se sospecha probable HPC, es intervenido quirúrgicamente de coordinación y el diagnóstico definitivo se realiza mediante estudio de anatomía patológica que incluye técnica inmunohistoquímica. A partir de este caso clínico ilustrativo se realizó una puesta al día sobre esta patología. DISCUSIÓN: a nivel intracraneano, los HPC tienen una distribución similar a los meningiomas, con una base de implantación dural. Tal es su similitud con los meningiomas, que fueron considerados como una variante meningoblástica o angiomatosas de los mismos. Desde 1993 se los clasifica como un grupo aparte, presentando 2 variantes: clásica, de bajo grado (grado II) y anaplásico (grado III). El estudio histopatológico (morfológico e inmunohistoquimico) es fundamental ya que los diferencia definitivamente a los meningiomas de los HCP. En cuanto a los marcadores, y siguiendo la bibliografía referente, nuestro caso reportado fue negativo para CD 34 pero positivo para factor VIIIa. CONCLUSIONES: los HPC del SNC son tumores poco frecuentes, con un comportamiento agresivo, tendencia a recurrir y dar metástasis a distancia. Por lo que es fundamental tener siempre presente este tipo de lesiones en patología tumoral de meninges. Un diagnóstico rápido con estudio histológico y confirmación immunohistoquímica permite llegar al diagnostico y a un tratamiento oportuno agresivo, ya que el mismo es lo único que está demostrado que mejora el pronóstico.(AU)

INTRODUCTION: the haemangio-pericytoma (HPC) is a rare hypervascular tumor that accounts for less than 1% of all the Central Nervous System (CNS) tumor and approximately 3% of the tumors involving the meninges. They are aggressive tumors that require an energetic therapy including surgery and radiotherapy, despite which the tumors tend to relapse, potentially giving rise to distant metastases. OBJECTIVES: to report the first case where the diagnosis is reached with the comprehensive immuno-histochemistry panel for HPC in Uruguay, and literature review based on that case. MATERIALS AND METHOD: we describe the case of a patient treated at the Hospital de Clínicas. Imaging studies suggested a potential HPC; the patient underwent scheduled surgery and the final diagnosis was reached through the pathology assessment, using immunohistochemistry. A literature review of the condition is presented on the basis of the clinical report. DISCUSSION: at an intracranial level, HPCs have a distribution similar to that of meningiomas, with a dural implantation. They are so much alike meningiomas that they were considered to be a meningoblastic or angiomatous variant of those tumors. Since 1993 they are classified as a separate group with 2 variations: classical, low-grade (grade II) and anaplastic (grade III). The histology test (morphological and immunohistochemistry) is essential, since it reveals the differences between HCPs and meningiomas. As to markers, in accordance with the bibliography, our case was reported as negative for CD 34 but was positive for factor VIIIa. CONCLUSIONS: SNC HPCs are uncommon tumors that behave aggressively; they tend to relapse and cause distant metastases. Hence, it is always crucial to bear this diagnosis in mind when facing a meningeal tumor. A quick diagnosis including histology and immuno-histochemical confirmation allows for a timely aggressive therapy- the only thing that improves prognosis.(AU)
Responsável: UY1.1 - BINAME - Biblioteca Nacional de Medicina


  9 / 4647 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Uruguai
(texto :
ES)
experimentalDocumentos relacionados
Id: 754173 LILACS-Express
Autor: Camejo, Claudia; Legman, Cecilia; Gaye, Andrés; Arcieri, Beatriz; Brumett, Florencia; Castro, Lorena; Peña, Alfredo; Gómez, Fabián; Higgie, Juan R; Preve, Federico; Salamano, Ronald.
Título: Unidad de ACV en el Hospital de Clínicas: comportamiento clínico-epidemiológico de los pacientes con ACV (2007-2012) / Stroke Unit at the Hospital de Clínicas: clinical-epidemiological behavior in patients with stroke (2007-2012)
Fonte: Arch. med. interna (Montevideo);37(1):30-35, mar. 2015. graf, tab.
Idioma: es.
Resumo: Introducción: El ataque cerebrovascular (ACV) es una importante causa de mortalidad, discapacidad y demencia en el mundo y en nuestro país. Provoca un gran impacto económico ya sea por gastos directos o indirectos. Objetivos: Describir aspectos clínicos, factores de riesgo e indicadores que permiten un adecuado manejo del ACV en su tratamiento agudo. Material y Métodos: Se realizó un estudio descriptivo y prospectivo de los ACV ingresados en el Hospital de Clínicas, entre 2007 y 2012 aplicando un protocolo con escalas clínicas, etiopatogénicas y funcionales, con test estadísticos adecuados. Resultados: Se protocolizaron 784 pacientes: 75% infartos, 16% hemorragias y 9% AIT. La HTA fue el factor de riesgo más frecuente. Un tercio llegó a puerta antes de las 4,5 h. En infartos y AIT se disminuyeron los días de internación y se mejoró la funcionalidad a 6 meses. Conclusiones: La formación de equipos entrenados en el diagnóstico y tratamiento del ACV disminuyeron el tiempo de internación y mejoraron la funcionalidad de estos pacientes.(AU)

Introduction: The cerebrospinal fluid (CSF) fistula is defined as the abnormal leak of fluid from the skull to outside the body through an osteomeningeal gap, which allows the passage of organisms to the intra-cranial space, with the risk of infection, potentially life-threatening. Divided as traumatic and non-traumatic, the condition is relatively common, and poses great challenges to neurosurgeons. Objective: to present the first case of post-traumatic CSF fistula in Uruguay, assessed with cistern MRI with diagnostic purposes. Case report: the case described is that of a patient that received treatment at the University Hospital (Hospital de Clínicas). The case is used to illustrate the condition and review the latest controversial issues involved in the algorithms for the diagnosis and therapy of the condition. Discussion: the main controversial issues found included the following: when to start prophylactic antibiotic (ATB) therapy following diagnosis; imaging tests requested for diagnosis, and type of therapy prescribed. Conclusions: The review of literature leads us to conclude that a correct diagnosis requires the routine use of CT and MRI; if doubts persist, cistern MRI, endoscopy, or cistern CT are indicated. With regards the therapeutic algorithm, we conclude that therapy should be conservative, applying medical therapy for two to four weeks; surgery will be prescribed if the fistula persists after that. Antibiotic therapy is an option and not a recommendation.(AU)
Responsável: UY1.1 - BINAME - Biblioteca Nacional de Medicina


  10 / 4647 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Costa Rica
(texto :
ES)
experimentalDocumentos relacionados
Id: 753654 LILACS-Express
Autor: Corrales-Aguilar, Eugenia.
Título: Reseña histórica, virología y ecología del Virus del Nilo Occidental: recomendaciones técnicas / Historical review, virology and ecologyof West Nile virus: technical recommendations
Fonte: Rev. costarric. salud pública;23(2):143-153, jul.-dic. 2014.
Idioma: es.
Resumo: El virus del nilo occidental (VON) representa un virus de importancia en la salud pública americana desde su introducción al hemisferio norte de este continente a finales de los años noventa. Este arbovirus se caracteriza por producir un cuadro febril y una enfermedad neuroinvasiva (encefalitis, meningitis o parálisis flácida). Debido a sus características epidemiológicas y virológicas y a la presencia de sus reservorios y vectores en nuestro país, este virus puede llegar a convertirse en una nueva enfermedad endémica en Costa Rica. Por lo tanto, es importante conocer los aspectos virológicos, clínicos, epidemiológicos y diagnósticos de este virus para estar preparados en caso de observar un aumento en la incidencia de la infección por VON. En esta revisión, se cubren aspectos clínicos, virológicos, epidemiológicos y diagnósticos relacionados a esta virosis.(AU)

West nile virus (WNV) represents an important virus for American public health since its introduction to the northern hemisphere of this continent in 1999. This arbovirus produces a febrile illness and a neuroinvasive disease (encephalitis, meningitis or flaccid paralysis). Due to its epidemiological and virological features and the local presence of its reservoirs and vectors, WNV represents a serious menace and could become one of the next novel endemic diseases in Costa Rica. Therefore, it is important to be aware of the virological, clinical, epidemiological and diagnostic aspects regarding this virus in order to be prepared in case there is an increase in local incidence of WNV infection. In this review, the clinical, virological, epidemiological and diagnostic features associated to this virus are discussed.(AU)
Responsável: CR1.1 - BINASSS - Biblioteca Nacional de Salud y Seguridad Social



página 1 de 465 ir para página                         
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde