Base de dados : LILACS
Pesquisa : Meningite [Descritor de assunto] OR Mening$ [Palavras]
Referências encontradas : 4489 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 449 ir para página                         

  1 / 4489 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
(texto :
EN)
Waldman, Eliseu Alves
experimentalDocumentos relacionados
Id: 719306 LILACS-Express
Autor: Tauil, Márcia de Cantuária; Carvalho, Cleidiane Santos Rodrigues de; Vieira, Ataiza César; Waldman, Eliseu Alves.
Título: Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil
Fonte: Braz. j. infect. dis;18(4):386-386, Jul-Aug/2014. tab, graf.
Idioma: en.
Projeto: Instituto Adolfo Lutz and the National Council for Scientific and Technological Development. 132840/2011-1.
Resumo: OBJECTIVES: To analyze the behavior of meningococcal disease in the Federal District, Brazil, from 2005 to 2011, and to assess the direct impact of the meningococcal serogroup C conjugate vaccine. METHODS: A descriptive study of cases of meningococcal disease among residents of the Federal District. We included in the study confirmed cases of meningococcal disease reported to the local surveillance. To reduce underreporting we compared data to the Brazilian Mortality Database and the Public Health Laboratory Database. We studied sociodemographic, clinical, and pathogen-related variables. For the assessment of the impact of meningococcal serogroup C conjugate vaccine, which was introduced in 2010 for children under two years of age, we compared the incidence of meningococcal disease before and after vaccine introduction in the recommended age groups for vaccination. RESULTS: We identified 309 cases of meningococcal disease, of which 52.1% were males. The average case fatality rate was 20.7%, the median age was three years and there was a predominance of serogroup C (70.2%) and C:23:P1.14-6 phenotype throughout the study period. In 2005-2009, 2010 and 2011, the incidence rates of meningococcal disease were 2.0, 1.8 and 0.8/100,000 inhabitants/year, while mortality rates were 0.4, 0.4 and 0.2/100,000 inhabitants/year, respectively. In the first and last periods, the incidence in poorer and more affluent areas were, respectively, 2.0 and 0.8, and 0.9 and 0.0/100,000 inhabitants/year. Comparing 2009 (the year prior to the introduction of meningococcal serogroup C conjugate vaccine) and 2011, there was 85% reduction in the incidence of serogroup C meningococcal disease in children under four years of age, from 9.0 to 1.3/100,000 (p < 0.01). CONCLUSIONS: The meningococcal serogroup C conjugate vaccine strategy implemented in Brazil proved highly effective and had a strong direct impact on the target population. However, case ...(AU)
Responsável: BR1.1 - BIREME


  2 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
(texto :
EN)
experimentalDocumentos relacionados
Id: 718124 LILACS-Express
Autor: Puri, Basant K.; Monro, Jean A.; Julu, Peter O. O.; Kingston, Michele C.; Shah, Mussadiq.
Título: Hyperosmia in Lyme disease / Hyperosmia na doença de Lyme
Fonte: Arq. neuropsiquiatr;72(8):597-597, 08/2014. tab.
Idioma: en.
Resumo: Neurological involvement in Lyme disease has been reported to include meningitis, cranial neuropathy and radiculoneuritis. While it is known that in some cases of asceptic meningitis patients may develop hyperosmia, the association between hyperosmia and Lyme disease has not previously been studied. Objective To carry out the first systematic study to ascertain whether hyperosmia is also a feature of Lyme disease. Method A questionnaire regarding abnormal sensory sensitivity in respect of the sense of smell was administered to 16 serologically positive Lyme disease patients and to 18 control subjects. Results The two groups were matched in respect of age, sex and body mass. None of the 34 subjects was suffering from migraine. Eight (50%) of the Lyme patients and none (0%) of the controls suffered from hyperosmia (p=0.0007). Conclusion This first systematic controlled study showed that Lyme disease is associated with hyperosmia. .(AU)

Tem sido descrito acometimento neurológico na doença de Lyme: meningite, neuropatia de nervos cranianos, e radiculoneurite. É bem conhecida a ocorrência de hiperosmia em alguns casos de meningites assépticas, mas a associação de hiperosmia com doença de Lyme ainda não foi relatada. Objetivo Conduzir um estudo sistemático para investigar se a hiperosmia é característica também da doença de Lyme. Método Foi aplicado um questionário pesquisando a ocorrência de sensibilidade anormal em relação ao sentido da olfação a 16 pacientes com sorologia positiva para doença de Lyme e a 18 controles normais. Os dois grupos foram pareados em relação a idade, sexo e massa corporal. Nenhum dos 34 sujeitos sofria de enxaqueca. Resultados Foi detectada hiperosmia em 8 sujeitos com doença de Lyme (50%) enquanto que a hiperosmia não apareceu em nenhum sujeito do grupo controle (p=0,0007). Conclusão Doença de Lyme está associada à hiperosmia. .(AU)
Responsável: BR1.1 - BIREME


  3 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 717343 LILACS-Express
Autor: Ramírez Quiñones, Jorge Alonso; Novoa Mosquera, María Elena.
Título: Absceso cerebral complicado con ruptura intraventricular: reporte de dos casos y revisión de la literatura / Intraventricular rupture of brain abscess: report of two cases and review of the literature
Fonte: An. Fac. Med. (Perú);75(2):159-163, abr. 2014. ilus.
Idioma: es.
Resumo: El absceso cerebral es una patología infecciosa infrecuente cuyo diagnóstico oportuno y tratamiento adecuado conducen a un buen pronóstico en la mayoría de los casos. La ruptura intraventricular es una complicación rara del absceso cerebral con elevada mortalidad; se caracteriza por compromiso brusco de la conciencia, con aparición de signos de irritación meníngea y hallazgos radiológicos compatibles con un drenaje de secreción purulenta hacia los ventrículos. El tratamiento incluye la administración de antibióticos intravenosos e intratecales asociados a una rápida intervención quirúrgica para drenaje del absceso y del contenido intraventricular. Presentamos dos casos de absceso cerebral complicado con ruptura intraventricular, que mostraron características clínicas y radiológicas propias de esta condición, con evolución favorable solo con tratamiento antibiótico endovenoso durante seis a diez semanas, respectivamente.(AU)

Brain abscess is an infrequent infectious disease that has a good prognosis in most of the cases with timely diagnosis and suitable treatment. Intraventricular rupture is a rare complication of the brain abscess with high mortality. It is characterized by a sudden consciousness compromise with signs of meningeal irritation and radiological findings compatible with purulent drainage into the ventricles. Treatment includes administration of intravenous and intrathecal antibiotics associated to prompt surgical intervention to drain the abscess and intraventricular content. Two cases of brain abscess complicated with intraventricular rupture showing clinical and radiological features typical of this condition and favorable outcome with intravenous antibiotic treatment during six and ten weeks respectively are reported.(AU)
Responsável: PE1.1 - DUGIC - Dirección Universitária de Gestión de la Información Científica


  4 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Cuba
(texto :
ES)
experimentalDocumentos relacionados
Id: 717205 LILACS-Express
Autor: Solórzano Álava, Luis Fernando; Martini Robles, Luiggi; Hernández Álvarez, Hilda; Sarracent Pérez, Jorge; Muzzio Aroca, Jenny; Rojas Rivero, Lázara.
Título: Angiostrongylus cantonensis: un parásito emergente en Ecuador / Angiostrongylus cantonensis / an emerging parasite in Ecuador
Fonte: Rev. cuba. med. trop;66(1):20-33, ene.-mar. 2014.
Idioma: es.
Resumo: Introducción: en 2008 se notificó por primera vez la presencia de Angiostrongylus cantonensis en Ecuador, así como los primeros casos de una enfermedad emergente causada por sus larvas, la meningitis eosinofilica. Métodos: se realizó una revisión de la literatura básica y actualizada sobre aspectos generales de Angiostrongylus cantonensis en el mundo y particulares en Ecuador, que incluyó los hallazgos parasitológicos, clínicos y malacológicos relacionados con la enfermedad. Resultados: se informan los hallazgos iniciales acerca de la aparición del parásito en Ecuador, así como la amplia distribución geográfica de sus hospederos intermediarios en el territorio nacional. Además, se notifican los brotes de meningitis eosinofilica por Angiostrongylus cantonensis y un caso de angiostrongyliosis ocular, informados oficialmente por el Ministerio de Salud Pública. Conclusiones: Angiostrongylus cantonensis es un parásito emergente en Ecuador, cuyo diagnóstico en la actualidad es clínico y epidemiológico, de ahí la importancia de contar con métodos de laboratorio que lo oriente. Por otra parte, es importante que se promuevan campañas de promoción y prevención de salud que contribuyan a romper la cadena de transmisión de la enfermedad.(AU)

Introduction: the presence of Angiostrongylus cantonensis and the first cases of eosinophilic meningitis, an emerging disease caused by its larvae, were first reported in Ecuador in the year 2008. Methods: a review was conducted of the basic and current bibliography on general aspects of Angiostrongylus cantonensis both worldwide and in Ecuador, including parasitological, clinical and malacological findings. Results: initial findings are reported about the emergence of the parasite in Ecuador, as well as the broad geographic distribution of its intermediate hosts in the national territory. Information is also provided about outbreaks of eosinophilic meningitis due to Angiostrongylus cantonensis and a case of ocular angiostrongylosis, based on official reports by the Ministry of Public Health. Conclusions: Angiostrongylus cantonensis is an emerging parasite in Ecuador whose diagnosis is currently based on clinical and epidemiological findings. Hence the importance of developing relevant laboratory methods. On the other hand, it is important to foster health promotion and prevention campaigns aimed at stopping the transmission of the disease.(AU)
Responsável: CU1.1 - Biblioteca Médica Nacional


  5 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Cuba
(texto :
ES)
experimentalDocumentos relacionados
Id: 717166 LILACS-Express
Autor: Rodríguez Fernández, Olga María; Sanchén Casas, Alexis; Prince Martínez, Ivette Alicia; Resik Aguirre, Sonia.
Título: Meningoencefalitis por echovirus30 complicada: reporte de dos casos / Complicated meningoencephalitis caused by echovirus30: report of two cases
Fonte: Arch. méd. Camaguey;18(3):317-326, abr.-jun. 2014.
Idioma: es.
Resumo: Introducción: entre los principales virus causales de meningoencefalitis de evolución benigna en el 95 % de los niños están los enterovirus. Ante la infrecuencia de la gravedad de estos procesos, presentamos dos infantes complicados a Echovirus 30 recluidos en la unidad de terapia intensiva del Hospital Pediátrico Provincial Docente Eduardo Agramonte Piña de Camagüey, con el objetivo de mostrar la capacidad de estos agentes de producir daños severos del sistema nervioso central. Casos clínicos: se presentaron niños de 11 meses y un año de edad respectivamente ambos remitidos del municipio de Florida en la provincia de Camagüey que presentaron fiebre, vómitos, somnolencia, astenia y anorexia; por lo que se les realizó punciones lumbares con resultados de aumento de las células a predominio linfocitario, además uno de ellos presentó graves trastornos de perfusión, edema cerebral severo, y leucograma con granulaciones tóxicas; el otro paciente a las 72 horas de su ingreso comenzó con irritabilidad, ataxia y movimientos incordinados de los brazos; por lo que se le diagnosticó una cerebelitis con pronóstico reservado. El estudio virológico de las heces de ambos enfermos realizado en el Instituto de Medicina Tropical en La Habana, arrojó ECHO virus 30. Los dos enfermos tuvieron estadía hospitalaria de 15 y 20 días respectivamente con diagnóstico de meningoencefalitis viral. Conclusiones: los casos expuestos nos muestran el potencial de los enterovirus como el ECHO 30 de producir meningoencefalitis de evolución seria e impredecible, aunque nuestros pacientes resolvieron sin secuelas, es importante la vigilancia mantenida hacia los enterovirus en la población infantil para prevenir las infecciones del sistema nervioso central.(AU)

Introduction: enteroviruses are among the main causal viruses of meningoencephalitis of mild evolution in the 95 % of children. Given the infrequency of the seriousness of these complaints, the cases of two infants complicated with echovirus 30 are presented. The patients were confined to the intensive care unit of the Eduardo Agramonte Piña Teaching Provincial Pediatric Hospital. The cases are presented with the objective of showing the capacity of these agents of producing severe damage in the central nervous system. Clinical cases: the cases of two infants of 11 months and one year old are presented; both infants were brought about a remission of the Florida municipality, province of Camagüey. Both patients presented vomits, sleepiness, asthenia, and anorexia; because of that, they underwent a lumbar puncture the results of which were as follow: increase of the cells with lymphocytic predominance. One of the patients also presented serious disorders of perfusion, severe brain edema and the leucograma produced the presence of toxic granulations; the other patient started presenting irritability, ataxia, and uncoordinated movements of the arms 72 hours after being admitted and was diagnosed with cerebellitis with a reserved prognosis. The virology study of the feces of both patients was made in the Tropical Medicine Institute in Havana; the study produced the following result: echovirus 30. The patients had a hospital stay of 15 and 20 days respectively and were diagnosed with viral meningoencephalitis. Conclusions: the cases presented show us the potential of enteroviruses like ECHO 30 of producing meningoencephalitis of serious and unpredictable evolution. Although the patients recovered without aftereffects, a maintained vigilance on enteroviruses in children is important to prevent infections in the central nervous system.(AU)
Responsável: CU1.1 - Biblioteca Médica Nacional


  6 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Cuba
(texto :
ES)
experimentalDocumentos relacionados
Id: 717131 LILACS-Express
Autor: Sanchén Casas, Alexis; Rodríguez Fernández, Olga María; Cordero Rodriguez, Magaly; Sarmiento Pérez, Luis Raymond.
Título: Frecuencia de enterovirus en niños con meningoencefalitis viral / Enterovirus frequency in children with viral meningoencephalitis
Fonte: Medisan;18(7):908-914, jun.-jul. 2014.
Idioma: es.
Resumo: Introducción: el enterovirus es uno de los agentes causales que suelen afectar el sistema nervioso central. Objetivos: determinar la frecuencia de enterovirus en niños hospitalizados con meningoencefalitis. Métodos: se efectuó un estudio descriptivo-observacional de 66 infantes con meningoencefalitis viral, ingresados en el Hospital Pediátrico Provincial "Dr. Eduardo Agramonte Piña" de la provincia de Camagüey, desde enero de 2011 hasta julio de 2012. Resultados: 26,6 % de los afectados fueron aislados por enterovirus en el año 2011 y 84,3 % en el 2012. El agente diagnosticado fue ECHO virus 30, el cual afectó todas las edades con positividad entre 63,0 y 100,0 %. Prevaleció el sexo masculino (78,4 %) procedentes de 11 municipios, con positividades superiores a 70 % en Florida y Camagüey. Los síntomas predominantes fueron cefaleas, fiebre, vómitos y malestar general. A la mayoría de los pacientes se le realizó estudio citoquímico del líquido cefaloraquídeo entre 10 y 199 células por 10(6)/L con predominio linfocitario. Conclusiones: gran parte de los afectados evolucionaron satisfactoriamente con hospitalización de solo 4 días.(AU)

Introduction: the enterovirus is one of the causal agents usually affecting the central nervous system. Objectives: to determine the enterovirus frequency in children hospitalized with meningoencephalitis. Methods: a descriptive-observational study of 66 infants with viral meningoencephalitis admitted in "Dr. Eduardo Agramonte Piña" Provincial Pediatric Hospital was carried out in Camagüey province from January, 2011 to July, 2012. Results: 26.6% of the affected ones were isolated due to enterovirus in the year 2011 and 84.3% in 2012. The diagnosed agent was ECHO virus 30, which affected all the ages with positivity between 63.0 and 100.0%. The male sex prevailed (78.4%) coming from 11 municipalities, with positivities higher than 70% in Florida and Camagüey. The predominant symptoms were migraines, fever, vomits and general uneasiness. Most of the patients had a cytochemical study of the cerebrospinal fluid from 10 and 199 cells per 106/L with lymphocytes prevalence. Conclusions: great number of the affected patients had a satisfactory clinical course with hospital stay of just 4 days.(AU)
Responsável: CU1.1 - Biblioteca Médica Nacional


  7 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 717034 LILACS-Express
Autor: Zuñiga Zambrano, Yenny Carolina; Vásquez, Rafael.
Título: Trastornos psiquiátricos en pacientes pediátricos con lupus eritematoso sistémico en un hospital de referencia / Psychiatric Disorders in Pediatric Patients With Systemic Lupus Erythematosus in a Reference Hospital
Fonte: Rev. colomb. psiquiatr;43(2):73-79, abr. 2014. ilus, tab.
Idioma: es.
Resumo: Objetivo: Describir las manifestaciones psiquiátricas de pacientes con lupus eritematoso sistémico atendidos en la Fundación Hospital de la Misericordia. Métodos: Estudio observacional descriptivo. Se revisaron historias clínicas y paraclínicos de pacientes hospitalarios y ambulatorios (2007-2013). Se seleccionó a 39 pacientes. Se utilizó SPSS19 para el análisis estadístico. Se consideró estadísticamente significativo un valor de p < 0,05. Resultados: La media de edad era 13,7 ± 2,33 (7-17) años; el 78,9% eran mujeres. Las manifestaciones psiquiátricas fueron trastorno de ansiedad (52,6%), trastorno adaptativo y depresión (el 36,8% cada uno), psicosis (10%), trastorno conversivo (7,9%) y trastorno obsesivo compulsivo (5,3%). La puntuación SLICC media fue 2,76 ± 2,8 y la SLEDAI, 20,81 ± 20,82. Los anticuerpos antinucleares fueron positivos en el 81,25%. El 65,8% tenía diagnóstico de lupus neuropsiquiátrico, el 23,7% con crisis epilépticas, el 36,8% con cefalea, el 13,2% con accidente cerebrovascular, y vasculitis, corea y meningitis (el 5,3% cada una). El tiempo promedio desde el diagnóstico fue 20,47 ± 22,2 meses, mínimo para trastorno adaptativo (15 meses) y máximo para trastorno conversivo (seudocrisis) (31 meses). Los pacientes con psicosis presentaron las más altas puntuaciones de actividad lúpica (35,5 ± 16,21 frente a 19,08 ± 13,72; p = 0,032) y daño por la enfermedad (SLICC, 4,25 ± 4,03 frente a 2,58 ± 2,67; p = 0,27) en comparación con otros diagnósticos. Conclusiones: Las manifestaciones psiquiátricas más frecuentes fueron trastorno de ansiedad, adaptativo y depresión, con frecuencias mayores que lo reportado en otras poblaciones. Se demostró actividad lúpica principalmente en los pacientes con psicosis.(AU)

Objective: To describe the psychiatric manifestations in pediatric patients with systemic erythematous lupus seen in the Fundación Hospital de la Misericordia. Methods: Observational descriptive study. Medical charts and test results of inpatients and outpatients between 2007 and2013 were reviewed; 39 patients were selected. SPSS 19 was used for statistical analysis. Statistical significance was considered with P= .05. Results: Mean age was 13.7 (2.33), with 78.9% female. The most frequent psychiatric manifestation was anxiety (52.6%), followed by adjustment disorder and depression (36.8% each one), psychosis (10%), conversion disorder (7.9%), and obsessive compulsive disorder (5.3%). The mean SLICC score was 2.76 (2.8), and the mean SLEDAI score was 20.81 (20.82). Antinuclear antibodies were positive in 81.25%. Neuropsychiatric lupus was diagnosed in 65.8% of patients; seizures were observed in 23.7%, headache in 36.8%, stroke in 13.2%, vasculitis, chorea 5.3%, and meningitis 5.3% of patients. The mean time from lupus diagnosis was 20.47 (22.2) months, with the shortest period for adjustment disorder and the longest period in patients with conversion disorder (pseudo-seizures) being 15 months and 31 months, respectively. The highest SLEDAI score was in patients with psychosis (35.5 [16.21] vs 19.08 [13.72]; P = .032), and also the highest disease damage (SLICC, 4.25 [4.03] vs 2.58 [2.67]; P = .27) in comparison with the other manifestations. Conclusions: The most frequent psychiatric manifestations were anxiety, depression, and adjustment disorder, with a higher frequency than other studies, and with lupus activity principally in patients with psychosis.(AU)
Responsável: CO332 - Facultad de Medicina


  8 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 716871
Autor: Emmerick, Isabel Cristina Martins; Campos, Mônica Rodrigues; Schramm, Joyce Mendes de Andrade; Silva, Raulino Sabino da; Costa, Maria de Fátima dos Santos.
Título: Estimativas corrigidas de casos de meningite, Brasil 2008-2009 / Adjusted estimates of meningitis case, Brazil 2008-2009
Fonte: Epidemiol. serv. saúde;23(2):215-226, jun. 2014. tab, ilus.
Idioma: pt.
Resumo: Objetivo: descrever estimativas corrigidas para o número de casos de meningite no Brasil, unidades da federação (UF) e macrorregiões em 2008-2009. Métodos: a proposta de correção pautou-se na letalidade, considerando-se os casos no Sistema de Informação de Agravos de Notificação (Sinan) e os óbitos no Sistema de Informações sobre Mortalidade (SIM), em três etapas – (1) seleção dos casos Sinan; (2) compatibilização dos códigos no Sinan-SIM, com obtenção do número de óbitos do SIM; e (3) avaliação do sub-registro e aplicação de proposta de correção do Sinan. Resultados: originalmente, obteve-se 9.229 casos de meningites no Sinan; após correção de 32,9 por cento, estimou-se 12.261 casos para o Brasil em 2008-2009; encontrou-se grande variabilidade nas UF e por grupo de gravidade. Conclusão: verificou-se subnotificação de casos de meningite no Sinan, em relação ao SIM; ressalta-se a importância de estratégias para o fortalecimento dos sistemas de informação, como a capacitação dos profissionais de saúde. (AU)

Objective: to describe adjusted estimates of meningitis case numbers for Brazil, the Brazilian states and regions, 2008-2009. Methods: the estimates were adjusted based on the meningitis fatality rate taking cases reported on the Notifiable Diseases Information System (SINAN) and deaths reported on the Mortality Information System (SIM). The method involved three stages: 1) Selection of SINAN cases; 2) SINAN and SIM code matching and obtaining the number of deaths from the SIM system; 3) SINAN underreporting assessment and adjustment. Results: 9,229 meningitis cases were initially found on SINAN. After adjustment, 12,261 cases were estimated in Brazil, 2008-2009. Considerable variability was found between states and between groups of meningitis severity. Conclusion: meningitis cases were underreported on SINAN, compared to SIM. The importance of strategies for strengthening information systems is highlighted, such as health professional training. (AU)
Descritores: Meningite
Vigilância Epidemiológica
-Técnicas de Estimativa
Sistemas de Informação em Saúde/utilização
Limites: Humanos
Responsável: BR275.1 - Biblioteca


  9 / 4489 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 716811
Autor: López, María Claudia Ortega; Salaiman, Janna Dalel Arboleda.
Título: Imunoglobulina endovenosa em pacientes pediátricos e adultos em unidades de terapia intensiva com síndrome de resposta inflamatória sistêmica grave e/ou síndrome de disfunção de múltiplos órgãos / Intravenous immunoglobulin in pediatric and adult patients in intensive care units with systemic inflammatory response syndrome and/or multiple organ dysfunction syndrome
Fonte: Braz. j. allergy immunol;1(3):149-154, maio-jun. 2013.
Idioma: pt.
Resumo: A literatura revela benefícios, em termos de sobrevivência, relacionados ao uso da imunoglobulina endovenosa em adultos com sepse hospitalizados em unidades de terapia intensiva, em comparação com pacientes tratados com placebo, ou com os que não sofreram intervenção. Em nossa prática clínica, alguns pacientes com sepse e/ou com síndrome de disfunção de múltiplos órgãos apresentam níveis de imunoglobulinas dentro das faixas utilizadas para interpretação do estado imunológico de indivíduos saudáveis. Desconhecemos se pacientes em estado crítico devido a infecção e inflamação poderiam ter a função das imunoglobulinas diminuída, a despeito de ter níveis de imunoglobulinas dentro da faixa de normalidade. O objetivo do presente artigo foi utilizar as informações dos resultados sobre segurança e eficácia publicados na literatura para intervenção com imunoglobulina humana endovenosa (IGIV), sobretudo em adultos com sepse e internados em unidades de terapia intensiva, numa tentativa de extrapolar os resultados para pacientes pediátricos com sepse e/ou com síndrome de disfunção de múltiplos órgãos, dando suporte ao seu uso durante as primeiras 12 e 24 horas em unidade de terapia intensiva pediátrica como coadjuvante, imunomodulador e anti-inflamatório, juntamente com a intervenção de rotina, em crianças com níveis "fisiologicamente normais" e/ou limítrofes baixos de IgG. Foram consultados os bancos de dados PubMed, MEDLINE e Cochrane de 1995 a 2011, com os seguintes termos: sepse, síndrome de disfunção orgânica múltipla, adultos, população pediátrica, unidade de terapia intensiva, e intervenção ou tratamento com imunoglobulina humana endovenosa. (AU)

The literature has described survival benefits associated with the use of intravenous immunoglobulin in adult patients admitted to intensive care units as compared to patients receiving placebo or no intervention. In our clinical practice, some patients with sepsis and/or multiple organ dysfunction syndrome show immunoglobulin levels within the normal ranges used to describe the immune status of healthy patients. It remains to be known whether a critically ill patient due to infection and inflammation could have an impaired immunoglobulin function despite showing normal immunoglobulin levels. The objective of this study was to review data on the safety and effectiveness of the use of intravenous immunoglobulin therapy in adult patients with sepsis admitted to intensive care units, in an attempt to extrapolate results to pediatric patients with sepsis and/or multiple organ dysfunction syndrome. The review focused on data supporting the use of intravenous immunoglobulin in the first 12-24 hours in the pediatric intensive care unit as an adjuvant, immunomodulatory, and anti-inflammatory agent, in addition to the routine intervention in children with “physiologically normal” or borderline low IgG levels. The PubMed, MEDLINE, and Cochrane databases were searched for articles published between 1995 and 2011, using the terms sepsis, multiple organ dysfunction syndrome, adult, pediatric population, intensive care unit, and intervention or treatment with human intravenous immunoglobulin. (AU)
Descritores: Imunoglobulinas Intravenosas
Síndrome de Waterhouse-Friderichsen
Unidades de Terapia Intensiva
Pediatria
-Terapêutica
Pacientes
Métodos
Técnicas e Procedimentos Diagnósticos
Resultado do Tratamento
Limites: Humanos
Masculino
Feminino
Criança
Adulto
Tipo de Publ: Revisão
Responsável: BR32.1 - SBIB - Serviço de Biblioteca e Informação Biomédica


  10 / 4489 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
experimentalDocumentos relacionados
Id: 716559
Autor: Quiroz F., Manuel; Drolett SF., Nicolás; Reyes J., Nakita; Zamorano D., Marcelo.
Título: Absceso del psoas tuberculoso, debut en paciente inmunodeprimido: presentación de un caso / Tuberculous psoas abscess, debut in immunocompromised patient: case report
Fonte: Rev. ANACEM (Impresa);7(2):103-106, ago. 2013. ilus.
Idioma: es.
Resumo: INTRODUCCIÓN: El absceso del psoas (AP) es una patología infrecuente de difícil diagnóstico. Se clasifica en primario o secundario teniendo como factor de riesgo común la inmunodeficiencia. PRESENTACIÓN DEL CASO: Paciente masculino de 40 años sin antecedentes mórbidos. Consulta por cuadro de un mes de evolución caracterizado por dolor lumbar derecho que aumenta al flexionar el muslo ipsilateral. Se asocia compromiso del estado general, dolor abdominal, sensación febril no cuantificada y bradipsiquia. La Tomografía computada (TC) de abdomen y pelvis mostró hipodensidad en relación al músculo psoas derecho diagnosticándose AP primario. El paciente evoluciona con shock séptico, siendo manejado con antibióticos de amplio espectro sin mejoría. Se realizan exámenes generales, Punción lumbar (PL) y Test de Elisa para VIH (TEVIH), resultando la PL compatible con Tuberculosis meníngea y el TE positivo. Se inició tratamiento empírico anti-tísico en espera del cultivo de Koch. Paciente evoluciona favorablemente. Se realiza una TC de control luego de dos semanas de tratamiento, que muestra imagen similar a la inicial, agregándose compromiso vertebral L4-L5, diagnosticándose Enfermedad de Pott (EP) y AP secundario. Se realiza punción y drenaje del absceso y se toma cultivo de Koch que resulta positivo. Paciente evoluciona asintomático, con buena respuesta al tratamiento. DISCUSIÓN: El AP secundario a EP es una entidad poco sospechada. Sin embargo, con métodos diagnósticos como la TC es posible realizar un diagnóstico precoz. Mycobacterium tuberculosis es una causa infrecuente de abscesos del psoas, pero debido al aumento de la población VIH positiva, es probable que aumente su incidencia.(AU)

INTRODUCTION: Psoas abscess is an uncommon disease with difficult diagnosis. It can be primary or secondary; immunodeficiency is among risk factors. CASE REPORT: 40 year-old male with no past medical history. He presented to the emergency department with right lumbar pain worsened with flexion of ipsilateral thigh. Involvement of general condition, abdominal pain, unquantified fever and bradypsychia were also present. Computed tomography (CT) scan of the abdomen and pelvis showed an hypodense lesion in the right psoas muscle. Primary psoas abscess was first diagnostic impression. Patient evolved to septic shock and was treated with broad spectrum antibiotics without improvement. General examinations were performed, lumbar puncture supported meningeal tuberculosis and HIV ELISA test was positive. Empirical quintuple therapy for tuberculosis was started before cerebrospinal fluid culture results, with favorable clinical evolution. Control CT scan was similar compared to first one but with L4 – L5 vertebrae involvement. Pott disease and secondary psoas abscess was diagnosed. Koch’s Bacillus culture from abscess puncture were positive. Patient had clinical improvement with antituberculous therapy. DISCUSSION: Psoas abscess is a rarely suspected patology, but with diagnostic methods as CT is possible to make an early diagnosis. Even though Mycobacterium tuberculosis is a rarer cause of psoas abscess, but more cases are expected due to the increased incidence of HIV – positive patients, more cases are expected eventually.(AU)
Descritores: Abscesso do Psoas/etiologia
Tuberculose da Coluna Vertebral/complicações
Tuberculose da Coluna Vertebral/radiografia
Infecções por HIV/complicações
-Tuberculose da Coluna Vertebral/quimioterapia
Infecções por HIV/quimioterapia
Hospedeiro Imunocomprometido
Infecções Oportunistas Relacionadas com a AIDS
Tomografia Computadorizada por Raios X
Ensaio de Imunoadsorção Enzimática
Terapia Antirretroviral de Alta Atividade
Limites: Humanos
Masculino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: CL1.1 - Biblioteca Central



página 1 de 449 ir para página                         
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde