Base de datos : MEDLINE
Búsqueda : Materiales and Biocompatibles [Palabras]
Referencias encontradas : 109577 [refinar]
Mostrando: 1 .. 10   en el formato [Detallado]

página 1 de 10958 va a la página                         

  1 / 109577 MEDLINE  
              next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:29346451
[Au] Autor:Chen H; Qian C; Liang C; Kang W
[Ad] Dirección:School of Materials Science and Engineering, Southeast University, Nanjing, Jiangsu province, China.
[Ti] Título:An approach for predicting the compressive strength of cement-based materials exposed to sulfate attack.
[So] Fuente:PLoS One;13(1):e0191370, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:In this paper, a support vector machine (SVM) model which can be used to predict the compressive strength of mortars exposed to sulfate attack was established. An accelerated corrosion test was applied to collect compressive strength data. For predicting the compressive strength of mortars, a total of 638 data samples obtained from experiment was chosen as a dataset to establish a SVM model. The values of the coefficient of determination, the mean absolute error, the mean absolute percentage error and the root mean square error were used for evaluating the predictive accuracy. The main factors affecting the predicted compressive strength were obtained by sensitivity analysis. A SVM model was calibrated, validated, and finally established. Moreover, the performance of the SVM model was compared to an artificial neural network (ANN) model. Results show that the prediction values from the SVM model were close to the experimental values; the main factors sensitive to concrete compressive strength were exposure time, water-cement ratio and sulfate ions; the performance of the SVM model was better than the ANN model. The SVM model developed in this study can be potentially used for predicting the compressive strength of cement-based materials servicing in harsh environments.
[Mh] Términos MeSH primario: Fuerza Compresiva
Materiales de Construcción
Ensayo de Materiales
Sulfatos
[Mh] Términos MeSH secundario: Redes Neurales (Computación)
Máquina de Vectores de Soporte
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nombre de substancia:
0 (Sulfates)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:180119
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191370


  2 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:29309430
[Au] Autor:Lilly JL; Gottipati A; Cahall CF; Agoub M; Berron BJ
[Ad] Dirección:Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky, United States of America.
[Ti] Título:Comparison of eosin and fluorescein conjugates for the photoinitiation of cell-compatible polymer coatings.
[So] Fuente:PLoS One;13(1):e0190880, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:Targeted photopolymerization is the basis for multiple diagnostic and cell encapsulation technologies. While eosin is used in conjunction with tertiary amines as a water-soluble photoinitiation system, eosin is not widely sold as a conjugate with antibodies and other targeting biomolecules. Here we evaluate the utility of fluorescein-labeled bioconjugates to photopolymerize targeted coatings on live cells. We show that although fluorescein conjugates absorb approximately 50% less light energy than eosin in matched photopolymerization experiments using a 530 nm LED lamp, appreciable polymer thicknesses can still be formed in cell compatible environments with fluorescein photosensitization. At low photoinitiator density, eosin allows more sensitive initiation of gelation. However at higher functionalization densities, the thickness of fluorescein polymer films begins to rival that of eosin. Commercial fluorescein-conjugated antibodies are also capable of generating conformal, protective coatings on mammalian cells with similar viability and encapsulation efficiency as eosin systems.
[Mh] Términos MeSH primario: Materiales Biocompatibles Revestidos
Eosina Amarillenta-(YS)/química
Fluoresceína/química
Luz
Polímeros/química
[Mh] Términos MeSH secundario: Células A549
Seres Humanos
Análisis por Matrices de Proteínas
Espectrofotometría Ultravioleta
[Pt] Tipo de publicación:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nombre de substancia:
0 (Coated Materials, Biocompatible); 0 (Polymers); TDQ283MPCW (Eosine Yellowish-(YS)); TPY09G7XIR (Fluorescein)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:180109
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190880


  3 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:29238193
[Au] Autor:Mahmood SK; Razak IA; Ghaji MS; Yusof LM; Mahmood ZK; Rameli MABP; Zakaria ZAB
[Ad] Dirección:Department of Veterinary Preclinical Science, Faculty of Veterinary Medicine, Universiti Putra Malaysia (UPM), Serdang, Malaysia.
[Ti] Título:In vivo evaluation of a novel nanocomposite porous 3D scaffold in a rabbit model: histological analysis.
[So] Fuente:Int J Nanomedicine;12:8587-8598, 2017.
[Is] ISSN:1178-2013
[Cp] País de publicación:New Zealand
[La] Idioma:eng
[Ab] Resumen:The healing of load-bearing segmental defects in long bones is a challenge due to the complex nature of the weight that affects the bone part and due to bending, shearing, axial, and torsional forces. An innovative porous 3D scaffolds implant of CaCO aragonite nanocomposite derived from cockle shell was advanced for substitute bone solely for load-bearing cases. The biomechanical characteristics of such materials were designed to withstand cortical bone strength. In promoting bone growth to the implant material, an ideal surface permeability was formed by means of freeze drying and by adding copolymers to the materials. The properties of coating and copolymers supplement were also assessed for bone-implant connection resolutions. To examine the properties of the material in advanced biological system, an experimental trial in an animal model was carried out. Critical sized defect of bone was created in rabbit's radial bone to assess the material for a load-bearing application with a short and extended period assessment with histological evaluation of the incorporated implanted material to the bone of the host. Trials in animal models proved that the material has the capability of enduring load-bearing conditions for long-term use devoid of breaking or generating stress that affects the host bone. Histological examination further confirmed the improved integration of the implanted materials to the host bone with profound bone development into and also above the implanted scaffold, which was attained with negligible reaction of the tissues to a foreign implanted material.
[Mh] Términos MeSH primario: Regeneración Ósea
Sustitutos de Huesos
Nanocompuestos/química
[Mh] Términos MeSH secundario: Animales
Fenómenos Biomecánicos
Huesos/fisiología
Huesos/cirugía
Masculino
Ensayo de Materiales
Porosidad
Conejos
Andamios del Tejido
Soporte de Peso
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Bone Substitutes)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:171215
[St] Status:MEDLINE
[do] DOI:10.2147/IJN.S145663


  4 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:29200852
[Au] Autor:Hu Y; Ke L; Chen H; Zhuo M; Yang X; Zhao D; Zeng S; Xiao X
[Ad] Dirección:Department of Pharmaceutics, School of Pharmaceutical Science, South-Central University for Nationalities.
[Ti] Título:Natural material-decorated mesoporous silica nanoparticle container for multifunctional membrane-controlled targeted drug delivery.
[So] Fuente:Int J Nanomedicine;12:8411-8426, 2017.
[Is] ISSN:1178-2013
[Cp] País de publicación:New Zealand
[La] Idioma:eng
[Ab] Resumen:To avoid the side effects caused by nonspecific targeting, premature release, weak selectivity, and poor therapeutic efficacy of current nanoparticle-based systems used for drug delivery, we fabricated natural material-decorated nanoparticles as a multifunctional, membrane-controlled targeted drug delivery system. The nanocomposite material coated with a membrane was biocompatible and integrated both specific tumor targeting and responsiveness to stimulation, which improved transmission efficacy and controlled drug release. Mesoporous silica nanoparticles (MSNs), which are known for their biocompatibility and high drug-loading capacity, were selected as a model drug container and carrier. The membrane was established by the polyelectrolyte composite method from chitosan (CS) which was sensitive to the acidic tumor microenvironment, folic acid-modified CS which recognizes the folate receptor expressed on the tumor cell surface, and a CD receptor-targeted polysaccharide hyaluronic acid. We characterized the structure of the nanocomposite as well as the drug release behavior under the control of the pH-sensitive membrane switch and evaluated the antitumor efficacy of the system in vitro. Our results provide a basis for the design and fabrication of novel membrane-controlled nanoparticles with improved tumor-targeting therapy.
[Mh] Términos MeSH primario: Materiales Biocompatibles/química
Sistemas de Liberación de Medicamentos
Membranas Artificiales
Nanopartículas/química
Dióxido de Silicio/química
[Mh] Términos MeSH secundario: Muerte Celular
Quitosano/química
Liberación de Fármacos
Endocitosis
Ácido Fólico/química
Células Hep G2
Seres Humanos
Nanopartículas/ultraestructura
Tamaño de la Partícula
Porosidad
Espectroscopía Infrarroja por Transformada de Fourier
Electricidad Estática
Temperatura Ambiental
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Biocompatible Materials); 0 (Membranes, Artificial); 7631-86-9 (Silicon Dioxide); 9012-76-4 (Chitosan); 935E97BOY8 (Folic Acid)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:171205
[St] Status:MEDLINE
[do] DOI:10.2147/IJN.S148438


  5 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28470446
[Au] Autor:Sundaran PS; Bhaskaran A; Alex ST; Prasad T; Haritha VH; Anie Y; Kumary TV; Anil Kumar PR
[Ad] Dirección:Division of Tissue Culture, Department of Applied Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695 012, India.
[Ti] Título:Drug loaded microbeads entrapped electrospun mat for wound dressing application.
[So] Fuente:J Mater Sci Mater Med;28(6):88, 2017 Jun.
[Is] ISSN:1573-4838
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:A new design of antibiotic loaded wound dressing and its initial in vitro evaluation is described. Chitosan microbeads loaded with ampicillin were sandwiched within polycaprolactone electrospun mat (MbAPPCL). The morphology was analyzed by scanning electron microscopy and surface chemistry was characterized by Fourier Transform Infrared Spectroscopy. In vitro cytotoxicity using L-929 fibroblast cells by direct contact test and elution assay revealed non-cytotoxic nature of MbAPPCL. The cell adhesion and viability analysis further confirmed the cytocompatibility of MbAPPCL as a wound dressing material. Percentage hemolysis and platelet adhesion on the mat exposed to blood substantiated the hemocompatibility. The antibiotic susceptibility test analyzed on Staphylococcus aureus by agar plate method confirmed the drug release and antimicrobial property. The proposed wound dressing model explained with ampicillin as a candidate drug has the potential to include microbeads with different antibiotics for multi drug treatment.
[Mh] Términos MeSH primario: Vendajes
Portadores de Fármacos
Microesferas
[Mh] Términos MeSH secundario: Animales
Antibacterianos/química
Antibacterianos/farmacología
Materiales Biocompatibles
Plaquetas
Línea Celular
Quitosano
Técnicas Electroquímicas
Fibroblastos/fisiología
Ensayo de Materiales
Ratones
Penicilinas/química
Penicilinas/farmacología
Staphylococcus aureus/efectos de los fármacos
Estreptomicina/química
Estreptomicina/farmacología
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Anti-Bacterial Agents); 0 (Biocompatible Materials); 0 (Drug Carriers); 0 (Penicillins); 9012-76-4 (Chitosan); Y45QSO73OB (Streptomycin)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5893-8


  6 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28470444
[Au] Autor:Lim PN; Feng J; Wang Z; Chong M; Konishi T; Tan LG; Chan J; Thian ES
[Ad] Dirección:Department of Mechanical Engineering, National University of Singapore, Singapore, 117 576, Singapore.
[Ti] Título:In-vivo evaluation of subcutaneously implanted cell-loaded apatite microcarriers for osteogenic potency.
[So] Fuente:J Mater Sci Mater Med;28(6):86, 2017 Jun.
[Is] ISSN:1573-4838
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:Cell-loaded apatite microcarriers present as potential scaffolds for direct in-vivo delivery of cells post-expansion to promote bone regeneration. The objective of this study was to evaluate the osteogenic potency of human foetal mesenchymal stem cells (hfMSC)-loaded apatite microcarriers when implanted subcutaneously in a mouse model. This was done by examining for ectopic bone formation at 2 weeks, 1 month and 2 months, which were intended to coincide with the inflammation, healing and remodelling phases, respectively. Three histological examinations including haematoxylin and eosin staining to examine general tissue morphology, Masson's trichrome staining to identify tissue type, and Von Kossa staining to examine extent of tissue mineralisation were performed. In addition, immunohistochemistry assay of osteopontin was conducted to confirm active bone formation by the seeded hfMSCs. Results showed a high level of tissue organisation and new bone formation, with active bone remodelling being observed at the end of 2 months, and an increase in tissue density, organisation, and mineralisation could also be observed for hfMSC-loaded apatite microcarriers. Various cell morphology resembling that of osteoblasts and osteoclasts could be seen on the surfaces of the hfMSC-loaded apatite microcarriers, with presence of woven bone tissue formation being observed at the intergranular space. These observations were consistent with evidence of ectopic bone formation, which were absent in group containing apatite microcarriers only. Overall, results suggested that hfMSC-loaded apatite microcarriers retained their osteogenic potency after implantation, and provided an effective platform for bone tissue regeneration.
[Mh] Términos MeSH primario: Apatitas/química
Trasplante de Células Madre Mesenquimatosas/métodos
Células del Estroma Mesenquimatoso/fisiología
Osteogénesis/fisiología
[Mh] Términos MeSH secundario: Animales
Diferenciación Celular
Seres Humanos
Ensayo de Materiales
Ratones
Ingeniería de Tejidos/métodos
Andamios del Tejido
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Apatites)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5897-4


  7 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28470445
[Au] Autor:Leroy A; Ribeiro S; Grossiord C; Alves A; Vestberg RH; Salles V; Brunon C; Gritsch K; Grosgogeat B; Bayon Y
[Ad] Dirección:Laboratoire des Multimatériaux et Interfaces, UMR 5615 CNRS-Université Lyon 1, Université de Lyon, 43 bd du 11 Novembre 1918, Villeurbanne, Cedex 69622, France.
[Ti] Título:FTIR microscopy contribution for comprehension of degradation mechanisms in PLA-based implantable medical devices.
[So] Fuente:J Mater Sci Mater Med;28(6):87, 2017 Jun.
[Is] ISSN:1573-4838
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:The integration and evolution of implantable medical devices made of bioresorbable polymers and used for temporary biomedical applications are crucial criteria in the success of a therapy and means of follow-up after implantation are needed. The objective of this work is to develop and evaluate a method based on microscopic Fourier Transform InfraRed spectroscopy (FTIR) mappings to monitor the degradation of such polymers on tissue explant sections, after implantation. This technique provided information on their location and on both their composition and crystallinity, which is directly linked to their state of degradation induced predominantly by chain scissions. An in vitro study was first performed on poly(L-lactic acid) (PLLA) meshes to validate the procedure and the assumption that changes observed on FTIR spectra are indeed a consequence of degradation. Then, mappings of in vivo degraded PLLA meshes were realized to follow up their degradation and to better visualize their degradation mechanisms. This work further warrants its translation to medical implants made of copolymers of lactic acid and to other polyesters.
[Mh] Términos MeSH primario: Implantes Absorbibles
Poliésteres/química
Espectroscopía Infrarroja por Transformada de Fourier
[Mh] Términos MeSH secundario: Animales
Materiales Biocompatibles
Equipos y Suministros
Masculino
Conejos
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Biocompatible Materials); 0 (Polyesters); 459TN2L5F5 (poly(lactide))
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5894-7


  8 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28467316
[Au] Autor:Chen R; Cai X; Ma K; Zhou Y; Wang Y; Jiang T
[Ad] Dirección:The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China.
[Ti] Título:The fabrication of double-layered chitosan/gelatin/genipin nanosphere coating for sequential and controlled release of therapeutic proteins.
[So] Fuente:Biofabrication;9(2):025028, 2017 Jun 01.
[Is] ISSN:1758-5090
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:Bone regeneration is a complicated process and includes a number of distinct and sequential stages of coordinated cellular actions under the regulation of multiple growth factors. Therefore, bone grafting materials in which growth factors can be incorporated and released in a programmed order in line with the bone tissue healing process may lead to desirable clinical outcomes. In the present study, a double-layered chitosan/gelatin/genipin (d-CSG/G) nanosphere coating is developed by using layer-by-layer electrophoretic deposition and genipin crosslinking. The surface morphology, physicochemical and mechanical properties of the coatings are explored. Cytochrome C is used as a therapeutic model protein and is successfully loaded on the inner and outer layers of the coating. The protein release can be controlled by the loading position, genipin concentration and thickness of the outer layer. Furthermore, the cell response to the coatings was evaluated. Real-time polymerase chain reactions, immunofluorescence staining and extracellular matrix mineralization assay confirmed that the functions of the loaded growth factor are fully preserved after fabrication. Overall, the d-CSG/G nanosphere coating could be a promising growth factor delivery system to promote bone tissue regeneration.
[Mh] Términos MeSH primario: Biomimética/métodos
Quitosano/química
Materiales Biocompatibles Revestidos/química
Citocromos c/uso terapéutico
Gelatina/química
Iridoides/química
Nanosferas/química
[Mh] Términos MeSH secundario: Animales
Proteína Morfogenética Ósea 2/química
Calcificación Fisiológica
Bovinos
Reactivos de Enlaces Cruzados/química
Preparaciones de Acción Retardada
Matriz Extracelular/metabolismo
Técnica del Anticuerpo Fluorescente
Células del Estroma Mesenquimatoso/citología
Nanosferas/ultraestructura
Osteocalcina/metabolismo
Ratas
Reacción en Cadena en Tiempo Real de la Polimerasa
Proteínas Recombinantes/química
Soluciones
Espectroscopía Infrarroja por Transformada de Fourier
Propiedades de Superficie
Factor de Crecimiento Transformador beta/química
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Bone Morphogenetic Protein 2); 0 (Coated Materials, Biocompatible); 0 (Cross-Linking Reagents); 0 (Delayed-Action Preparations); 0 (Iridoids); 0 (Recombinant Proteins); 0 (Solutions); 0 (Transforming Growth Factor beta); 0 (recombinant human bone morphogenetic protein-2); 104982-03-8 (Osteocalcin); 9000-70-8 (Gelatin); 9007-43-6 (Cytochromes c); 9012-76-4 (Chitosan); A3V2NE52YG (genipin)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170504
[St] Status:MEDLINE
[do] DOI:10.1088/1758-5090/aa70c3


  9 / 109577 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28462910
[Au] Autor:Mihailescu IN; Bociaga D; Popescu-Pelin G; Stan GE; Duta L; Socol G; Chifiriuc MC; Bleotu C; Lazar V; Husanu MA; Zgura I; Miculescu F; Negut I; Hapenciuc C
[Ad] Dirección:National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.
[Ti] Título:Optimized silicon reinforcement of carbon coatings by pulsed laser technique for superior functional biomedical surfaces fabrication.
[So] Fuente:Biofabrication;9(2):025029, 2017 Jun 01.
[Is] ISSN:1758-5090
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:We report on the fabrication of silicon-reinforced carbon (C:Si) structures by combinatorial pulsed laser deposition to search for the best design for a new generation of multi-functional coated implants. The synthesized films were characterized from the morphological, structural, compositional, mechanical and microbiological points of view. Scanning electron microscopy revealed the presence, on top of the deposited layers, of spheroid particulates with sizes in the micron range. No micro-cracks or delaminations were observed. Energy dispersive x-ray spectroscopy and grazing incidence x-ray diffraction pointed to the existence of a C to Si compositional gradient from one end of the film to the other. Raman investigation revealed a relatively high sp hybridization of up to 80% at 40-48 mm apart from the edge with higher C content. Si addition was demonstrated to significantly increase C:Si film bonding to the substrate, with values above the ISO threshold for coatings to be used in high-loading biomedical applications. Surface energy studies pointed to an increase in the hydrophilic character of the deposited structures along with Si content up to 52 mN m . In certain cases, the Si-reinforced C coatings elicited an antimicrobial biofilm action. The presence of Si was proven to be benign to HEp-2 cells of human origin, without interfering with their cellular cycle. On this basis, reliable C:Si structures with good adherence to the substrate and high efficiency against microbial biofilms can be developed for implant coatings and other advanced medical devices.
[Mh] Términos MeSH primario: Tecnología Biomédica/métodos
Carbono/química
Materiales Biocompatibles Revestidos/química
Rayos Láser
Silicio/química
[Mh] Términos MeSH secundario: Ciclo Celular
Forma de la Célula
Seres Humanos
Ensayo de Materiales
Pruebas de Sensibilidad Microbiana
Microscopía Electrónica de Rastreo
Espectrometría por Rayos X
Espectrometría Raman
Propiedades de Superficie
Agua/química
Difracción de Rayos X
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Coated Materials, Biocompatible); 059QF0KO0R (Water); 7440-44-0 (Carbon); Z4152N8IUI (Silicon)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170503
[St] Status:MEDLINE
[do] DOI:10.1088/1758-5090/aa7076


  10 / 109577 MEDLINE  
              first record previous record
selecciona
para imprimir
Fotocopia
Texto completo
[PMID]:28455252
[Au] Autor:Kwak HW; Shin M; Lee JY; Yun H; Song DW; Yang Y; Shin BS; Park YH; Lee KH
[Ad] Dirección:Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
[Ti] Título:Fabrication of an ultrafine fish gelatin nanofibrous web from an aqueous solution by electrospinning.
[So] Fuente:Int J Biol Macromol;102:1092-1103, 2017 Sep.
[Is] ISSN:1879-0003
[Cp] País de publicación:Netherlands
[La] Idioma:eng
[Ab] Resumen:Electrospinning of aqueous gelatin solution obtained from bovine or porcine sources has been difficult to achieve without additional facilities, such as a temperature control oven or heating cover. Gelatin from cold-water fish has low contents of proline (Pro) and hydroxyproline (Hyp) compared with mammalian-derived gelatin. For this reason, the fish-derived gelatin maintains a sol state without showing gelation behavior at room temperature. In the present study, we prepared an ultrafine fish gelatin nanofibrous web by electrospinning from aqueous solutions without any additive polymers or temperature control facilities. The concentration and viscosity of fish gelatin are the most important factor in determining the electrospinnability and fiber diameter. Electrospinning of aqueous fish gelatin has the highest nanofiber productivity compared to other organic solvent systems. Using glutaraldehyde vapor (GTA), the water stability was improved and substantial enhancement was achieved in the mechanical properties. Finally, the cytotoxicity of a fish gelatin nanofibrous scaffold was evaluated based on a cell proliferation study by culturing human dermal fibroblasts (HDFs) compared with a fish gelatin film and nanofibrous mat from mammalian gelatin. The result shows better initial cell attachment and proliferation compared with the fish gelatin film and no significant difference compared with mammalian-derived gelatin nanofibrous mat. We expect that electrospinning of aqueous fish gelatin could be an effective alternative mammalian gelatin source.
[Mh] Términos MeSH primario: Electricidad
Peces
Gelatina/química
Nanofibras/química
Nanotecnología
Agua/química
[Mh] Términos MeSH secundario: Animales
Materiales Biocompatibles/química
Materiales Biocompatibles/farmacología
Bovinos
Adhesión Celular/efectos de los fármacos
Proliferación Celular/efectos de los fármacos
Fibroblastos/citología
Fibroblastos/efectos de los fármacos
Gelatina/farmacología
Glutaral/química
Seres Humanos
Hidrólisis
Reología
Soluciones
Viscosidad
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Biocompatible Materials); 0 (Solutions); 059QF0KO0R (Water); 9000-70-8 (Gelatin); T3C89M417N (Glutaral)
[Em] Mes de ingreso:1803
[Cu] Fecha actualización por clase:180309
[Lr] Fecha última revisión:180309
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170430
[St] Status:MEDLINE



página 1 de 10958 va a la página                         
   


Refinar la búsqueda
  Base de datos : MEDLINE Formulario avanzado   

    Buscar en el campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPS/OMS - Centro Latinoamericano y del Caribe de Información en Ciencias de la Salud