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  1 / 19053 MEDLINE  
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[PMID]:29018086
[Au] Autor:Madan S; Beri S
[Ad] Dirección:Department of Ophthalmology, Lady Hardinge Medical College and Associated Smt. Sucheta Kriplani Hospital & Kalawati Saran Children's Hospital, University of Delhi, New Delhi, India drsiddharthmadan@gmail.com.
[Ti] Título:Bitot spot: early marker for avoidable blindness.
[So] Fuente:CMAJ;189(40):E1264, 2017 10 10.
[Is] ISSN:1488-2329
[Cp] País de publicación:Canada
[La] Idioma:eng
[Mh] Términos MeSH primario: Conjuntiva/patología
Ceguera Nocturna/etiología
Deficiencia de Vitamina A/complicaciones
Xeroftalmia/complicaciones
[Mh] Términos MeSH secundario: Niño
Diagnóstico Diferencial
Humanos
Masculino
Ceguera Nocturna/diagnóstico
Deficiencia de Vitamina A/diagnóstico
Xeroftalmia/diagnóstico
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:171011
[St] Status:MEDLINE
[do] DOI:10.1503/cmaj.170792


  2 / 19053 MEDLINE  
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[PMID]:28860044
[Au] Autor:Labowsky MT; Stinnett SS; Liss J; Daluvoy M; Hall RP; Shieh C
[Ad] Dirección:Duke University School of Medicine, Durham, North Carolina. Electronic address: marytlabowsky@gmail.com.
[Ti] Título:Clinical Implications of Direct Immunofluorescence Findings in Patients With Ocular Mucous Membrane Pemphigoid.
[So] Fuente:Am J Ophthalmol;183:48-55, 2017 Nov.
[Is] ISSN:1879-1891
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:PURPOSE: To examine the clinical implications of positive or negative direct immunofluorescence biopsies (DIF) in patients with clinically typical ocular mucous membrane pemphigoid (MMP). DESIGN: Retrospective cohort study. METHODS: The study population was patients with clinically typical ocular MMP disease with documented DIF results who were followed for at least 1 year at the Duke University multidisciplinary ocular MMP clinic. Data were collected by chart review and included patient demographics, clinical examination findings, and history of autoimmune disease and/or malignancy, as well as topical, systemic, and surgical treatments received. Main outcome measures included MMP Disease Area Index, Foster stages, proportion legally blind, duration of follow-up, and use of systemic immunosuppression and ocular procedures in treatment. RESULTS: In multivariable analysis restricted to 55 patients, patients with negative and positive biopsies were similar in the outcome measures; however, positive-biopsy patients were more likely to be treated with systemic immunosuppression and were followed for longer at our clinic. Patients with isolated ocular disease were also more likely to have negative biopsies compared to those who also had extraocular disease. Patients who had conjunctival biopsies were more likely to have a negative direct immunofluorescence result than patients with biopsies from other sites. CONCLUSIONS: We encourage clinicians and patients to consider treatment with systemic immunosuppression even in the absence of diagnosis confirmation by DIF. Furthermore, this study supports current standard of care to pursue a nonocular biopsy of normal-appearing, perilesional skin or oral mucosa when possible.
[Mh] Términos MeSH primario: Autoanticuerpos/análisis
Conjuntiva/patología
Enfermedades de la Conjuntiva/diagnóstico
Técnica del Anticuerpo Fluorescente Directa/métodos
Penfigoide Benigno de la Membrana Mucosa/diagnóstico
[Mh] Términos MeSH secundario: Adulto
Anciano
Anciano de 80 o más Años
Autoanticuerpos/inmunología
Membrana Basal/patología
Biopsia
Enfermedades de la Conjuntiva/inmunología
Femenino
Estudios de Seguimiento
Humanos
Masculino
Mediana Edad
Penfigoide Benigno de la Membrana Mucosa/inmunología
Reproducibilidad de Resultados
Estudios Retrospectivos
Índice de Severidad de la Enfermedad
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Autoantibodies)
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:170901
[St] Status:MEDLINE


  3 / 19053 MEDLINE  
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[PMID]:28858960
[Au] Autor:Medeiros Pinto J; Pinto Ferreira N; Abegão Pinto L
[Ad] Dirección:*Department of Ophthalmology, Hospital Santa Maria, Centro Hospitalar Lisboa Norte ‡Visual Sciences Study Center, Faculdade de Medicina, Universidade de Lisboa, Lisbon †Department of Ophthalmology, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal.
[Ti] Título:Ahmed Valve Upstream Obstruction Caused by Fibrous Ingrowth: Surgical Approach.
[So] Fuente:J Glaucoma;26(10):e236-e238, 2017 Oct.
[Is] ISSN:1536-481X
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:Glaucoma secondary to penetrating keratoplasty can be challenging and multiple surgeries may be needed to control the intraocular pressure (IOP), including the use of glaucoma drainage implants. However, late failure of these drainage implant surgery is common, mostly because of excessive scarring or bleb encapsulation which may require further surgical intervention. We present a case of a young patient referred for advanced glaucoma secondary to penetrating keratoplasty and chronic uveitis. He presented with elevated IOP under maximal therapy, already with 2 failed trabeculectomies and a nonfunctional Ahmed Valve. As no bleb was seen overlying the plate of the valve, an exploratory surgical revision was scheduled. The cause for defective aqueous humour drainage was identified as a fibrovascular ingrowth into the valve's plate slit. We proceeded with removal of this membrane, as well as confirmation of patency with trypan blue and application of mitomycin C to prevent recurrence of the fibrous ingrowth. With a 6 month follow-up, a diffuse bleb exists over the plate, with IOP values within the target values for this patient (<16 mm Hg). This exploratory procedure identified an unusual cause for drainage device failure, as well as reporting its management without explanting the device.
[Mh] Términos MeSH primario: Conjuntiva/patología
Remoción de Dispositivos/métodos
Implantes de Drenaje de Glaucoma/efectos adversos
Glaucoma/cirugía
Presión Intraocular
[Mh] Términos MeSH secundario: Adulto
Fibrosis/etiología
Glaucoma/etiología
Glaucoma/fisiopatología
Humanos
Queratoplastia Penetrante/efectos adversos
Masculino
Falla de Prótesis
Reoperación
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170831
[St] Status:MEDLINE
[do] DOI:10.1097/IJG.0000000000000739


  4 / 19053 MEDLINE  
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[PMID]:28777223
[Au] Autor:Babic K; Siguan-Bell C; Hee M; Lin SC
[Ad] Dirección:*Department of Ophthalmology, University of California, San Francisco ‡Pacific Eye Specialists, Daly City, CA †Department of Ophthalmology and Visual Sciences, University of the Philippines-Philippine General Hospital, Manila, Philippines.
[Ti] Título:Ocular Gossypiboma: Ultrasound B-Scan Assessment of Retained Surgical Sponge After Ahmed Valve Surgery: A Case Report.
[So] Fuente:J Glaucoma;26(10):e239-e241, 2017 Oct.
[Is] ISSN:1536-481X
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:PURPOSE OF THE STUDY: To present the first documented case of an ocular gossypiboma (retained foreign body) of a mitomycin-C-soaked sponge confirmed echographically using diagnostic ultrasound B-scan after Ahmed valve surgery. PATIENTS AND METHODS: A patient who underwent phacoemulsification with Ahmed valve implantation surgery had a retained Weck-Cels sponge soaked with mitomycin-C. With the use of ocular ultrasound B-scan, the retained sponge was localized and a second procedure was performed to explant it. CONCLUSION: In cases of ocular gossypiboma the use of ultrasound modalities can be a valuable tool especially because B-scan access is common and can be cost-effective.
[Mh] Términos MeSH primario: Conjuntiva
Cuerpos Extraños en el Ojo/diagnóstico
Cuerpos Extraños/diagnóstico
Implantes de Drenaje de Glaucoma/efectos adversos
Complicaciones Posoperatorias
Ultrasonografía/métodos
[Mh] Términos MeSH secundario: Anciano
Remoción de Dispositivos
Cuerpos Extraños en el Ojo/etiología
Cuerpos Extraños en el Ojo/cirugía
Femenino
Cuerpos Extraños/etiología
Glaucoma/cirugía
Humanos
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170804
[St] Status:MEDLINE
[do] DOI:10.1097/IJG.0000000000000744


  5 / 19053 MEDLINE  
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[PMID]:28750630
[Au] Autor:Ong SJ; Jung SM; Lin HC
[Ad] Dirección:Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan.
[Ti] Título:Conjunctival lymphoma during pregnancy: a case report.
[So] Fuente:BMC Ophthalmol;17(1):131, 2017 Jul 27.
[Is] ISSN:1471-2415
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION: A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right upper lid. The remaining ophthalmic examination was unremarkable. Histopathology and immunohistochemistry showed mucosa-associated lymphoid tissue (MALT) lymphoma with immunoglobulin kappa monotype. Further workup showed no evidence of systemic lymphoma or orbital involvement. CONCLUSIONS: Partial regrowth of conjunctival lymphoma occurred 6 months after excision and the MALT lymphoma remained indolent during the course of her pregnancy without radiotherapy.
[Mh] Términos MeSH primario: Conjuntiva/patología
Neoplasias de la Conjuntiva/diagnóstico
Linfoma de Células B de la Zona Marginal/diagnóstico
Complicaciones Neoplásicas del Embarazo
[Mh] Términos MeSH secundario: Adulto
Biopsia
Femenino
Humanos
Inmunohistoquímica
Recién Nacido
Embarazo
Resultado del Embarazo
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170728
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0518-z


  6 / 19053 MEDLINE  
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[PMID]:28457312
[Au] Autor:Skorin L; Turpin S
[Ti] Título:Minocycline-induced hyperpigmentation of the skin, sclera, and palpebral conjunctiva.
[So] Fuente:Can J Ophthalmol;52(2):e79-e81, 2017 Apr.
[Is] ISSN:1715-3360
[Cp] País de publicación:England
[La] Idioma:eng
[Mh] Términos MeSH primario: Conjuntiva/patología
Enfermedades de la Conjuntiva/inducido químicamente
Hiperpigmentación/inducido químicamente
Minociclina/efectos adversos
Esclerótica/patología
Enfermedades de la Esclerótica/inducido químicamente
[Mh] Términos MeSH secundario: Anciano de 80 o más Años
Antibacterianos/efectos adversos
Artritis Infecciosa/quimioterapia
Conjuntiva/efectos de drogas
Enfermedades de la Conjuntiva/diagnóstico
Femenino
Humanos
Hiperpigmentación/diagnóstico
Esclerótica/efectos de drogas
Enfermedades de la Esclerótica/diagnóstico
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Anti-Bacterial Agents); FYY3R43WGO (Minocycline)
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170501
[St] Status:MEDLINE


  7 / 19053 MEDLINE  
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[PMID]:28389894
[Au] Autor:Sa HS; Seo JW; Kang S
[Ad] Dirección:Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic 43-gil, Songpa-gu, Seoul, 05505, Korea. lineblue@hanmail.net.
[Ti] Título:Upper fornix approach combined with a superior lateral cantholysis: a minimally invasive approach to the superonasal intraconal space.
[So] Fuente:Jpn J Ophthalmol;61(4):361-367, 2017 Jul.
[Is] ISSN:1613-2246
[Cp] País de publicación:Japan
[La] Idioma:eng
[Ab] Resumen:PURPOSE: To present a new minimally invasive approach to the deep superonasal orbit. METHODS: This retrospective study reviewed seven consecutive patients who underwent orbital surgery using an upper conjunctival fornix approach combined with a superior lateral cantholysis for tumors in the superonasal intraconal space. Charts were reviewed for demographic, radiological, clinical, and surgical data including surgical outcome and morbidities for each patient. RESULTS: Six benign tumors of the superonasal intraconal orbit were successfully exposed and removed using this approach, and one malignant tumor was biopsied for diagnosis. Histopathology revealed cavernous haemangioma (3 cases), solitary fibrous tumor (2 cases), schwannoma (1 case), and diffuse large B cell lymphoma (1 case). Visual acuity and ocular motility were unchanged or improved in all cases. There were no visible scars or other complications related to this approach. CONCLUSION: The upper fornix approach combined with a superior lateral cantholysis is a novel technique that provides safe and excellent exposure of the deep superonasal orbit. In addition, it avoids the unnecessary morbidity of upper lid splitting, medial rectus muscle detachment, or bone removal.
[Mh] Términos MeSH primario: Conjuntiva/cirugía
Párpados/cirugía
Hemangioma Cavernoso/cirugía
Procedimientos Quirúrgicos Mínimamente Invasivos/métodos
Músculos Oculomotores/cirugía
Procedimientos Quirúrgicos Oftalmológicos/métodos
Neoplasias Orbitales/cirugía
[Mh] Términos MeSH secundario: Adulto
Anciano
Femenino
Estudios de Seguimiento
Hemangioma Cavernoso/diagnóstico
Humanos
Masculino
Mediana Edad
Neoplasias Orbitales/diagnóstico
Estudios Retrospectivos
Factores de Tiempo
Tomografía Computarizada por Rayos X
Resultado del Tratamiento
[Pt] Tipo de publicación:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170408
[St] Status:MEDLINE
[do] DOI:10.1007/s10384-017-0514-0


  8 / 19053 MEDLINE  
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[PMID]:28237169
[Au] Autor:Lassalle S; Maschi C; Caujolle JP; Giordanengo V; Hofman P
[Ad] Dirección:Laboratoire de Pathologie Clinique et Expérimentale, Hôpital Pasteur, Nice, France. Electronic address: lassalle.s@chu-nice.fr.
[Ti] Título:Inverted conjunctival papilloma: a certainly underestimated high-risk lesion for carcinomatous transformation-a case report.
[So] Fuente:Can J Ophthalmol;52(1):e30-e31, 2017 Feb.
[Is] ISSN:1715-3360
[Cp] País de publicación:England
[La] Idioma:eng
[Mh] Términos MeSH primario: Transformación Celular Neoplásica/patología
Conjuntiva/patología
Neoplasias de la Conjuntiva/diagnóstico
Papiloma Invertido/diagnóstico
[Mh] Términos MeSH secundario: Biopsia
Diagnóstico Diferencial
Humanos
Masculino
Mediana Edad
Factores de Riesgo
[Pt] Tipo de publicación:CASE REPORTS; JOURNAL ARTICLE
[Em] Mes de ingreso:1711
[Cu] Fecha actualización por clase:171102
[Lr] Fecha última revisión:171102
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170226
[St] Status:MEDLINE


  9 / 19053 MEDLINE  
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[PMID]:28795228
[Au] Autor:Quaranta L; Katsanos A; Legramandi L; Riva I
[Ad] Dirección:Department of Medical and Surgical Specialties, University of Brescia, Brescia, Italy. luciano.quaranta@unibs.it.
[Ti] Título:Subconjunctival injections of 5-fluorouracil for failing Ahmed glaucoma implants.
[So] Fuente:Graefes Arch Clin Exp Ophthalmol;255(11):2293-2294, 2017 11.
[Is] ISSN:1435-702X
[Cp] País de publicación:Germany
[La] Idioma:eng
[Mh] Términos MeSH primario: Fluorouracilo
Glaucoma
[Mh] Términos MeSH secundario: Conjuntiva
Implantes de Drenaje de Glaucoma
Humanos
Inyecciones
Presión Intraocular
Resultado del Tratamiento
[Pt] Tipo de publicación:LETTER; COMMENT
[Nm] Nombre de substancia:
U3P01618RT (Fluorouracil)
[Em] Mes de ingreso:1710
[Cu] Fecha actualización por clase:171031
[Lr] Fecha última revisión:171031
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170810
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3768-9


  10 / 19053 MEDLINE  
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[PMID]:28601250
[Au] Autor:Schlenker MB; Gulamhusein H; Conrad-Hengerer I; Somers A; Lenzhofer M; Stalmans I; Reitsamer H; Hengerer FH; Ahmed IIK
[Ad] Dirección:Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada. Electronic address: matt.schlenker@utoronto.ca.
[Ti] Título:Efficacy, Safety, and Risk Factors for Failure of Standalone Ab Interno Gelatin Microstent Implantation versus Standalone Trabeculectomy.
[So] Fuente:Ophthalmology;124(11):1579-1588, 2017 Nov.
[Is] ISSN:1549-4713
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:PURPOSE: To compare the efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation with mitomycin C (MMC) versus trabeculectomy with MMC. DESIGN: International, multicenter, retrospective interventional cohort study. PARTICIPANTS: Three hundred fifty-four eyes of 293 patients (185 microstent and 169 trabeculectomy) with no prior incisional surgery. METHODS: Consecutive eyes with uncontrolled glaucoma underwent microstent or trabeculectomy surgery from January 1, 2011 through July 31, 2015 at 4 academic ophthalmology centers: Toronto, Canada; Frankfurt, Germany; Salzburg, Austria; and Leuven, Belgium. MAIN OUTCOME MEASURES: Primary outcome measure was hazard ratio (HR) of failure, with failure defined as 2 consecutive intraocular pressure (IOP) readings of <6 mmHg with vision loss or >17 mmHg without glaucoma medications (complete success) at least 1 month after surgery despite in-clinic interventions (including needling). Secondary outcome measures included IOP thresholds of 6 to 14 mmHg and 6 to 21 mmHg and same thresholds allowing for medications (qualified success), interventions, complications, and reoperations. RESULTS: Baseline characteristics were similar, except more men (56% vs. 43%), younger patients (average, by 3 years), better preoperative visual acuity (22% vs. 32% with 0.4 logarithm of the minimum angle of resolution vision or worse), and more trabeculoplasty (52% vs. 30%) among microstent eyes. The adjusted HR of failure of the microstent relative to trabeculectomy was 1.2 (95% confidence interval [CI], 0.7-2.0) for complete success and 1.3 (95% CI, 0.6-2.8) for qualified success, and similar for other outcomes. Time to 25% failure was 11.2 months (95% CI, 6.9-16.1 months) and 10.6 months (95% CI, 6.8-16.2 months) for complete success and 30.3 months (95% CI, 19.0-∞ months) and 33.3 months (95% CI, 25.7-46.2 months) for qualified success. Overall, white ethnicity was associated with decreased risk of failure (adjusted HR, 0.49; 95% CI, 0.25-0.96), and diabetes was associated with increased risk of failure (adjusted HR, 4.21; 95% CI, 2.10-8.45). There were 117 and 165 distinct interventions: 43% and 31% underwent needling, respectively, and 50% of trabeculectomy eyes underwent laser suture lysis. There were 22 and 30 distinct complications, although most were transient. Ten percent and 5% underwent reoperation (P = 0.11). CONCLUSIONS: There was no detectable difference in risk of failure and safety profiles between standalone ab interno microstent with MMC and trabeculectomy with MMC.
[Mh] Términos MeSH primario: Alquilantes/administración & dosificación
Gelatina
Implantes de Drenaje de Glaucoma
Glaucoma/cirugía
Mitomicina/administración & dosificación
Falla de Prótesis
Trabeculectomía
[Mh] Términos MeSH secundario: Anciano
Conjuntiva/efectos de drogas
Femenino
Estudios de Seguimiento
Glaucoma/fisiopatología
Humanos
Presión Intraocular/fisiología
Masculino
Mediana Edad
Implantación de Prótesis
Estudios Retrospectivos
Factores de Riesgo
Gestión de la Seguridad
Tonometría Ocular
Resultado del Tratamiento
[Pt] Tipo de publicación:COMPARATIVE STUDY; JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nombre de substancia:
0 (Alkylating Agents); 50SG953SK6 (Mitomycin); 9000-70-8 (Gelatin)
[Em] Mes de ingreso:1710
[Cu] Fecha actualización por clase:171030
[Lr] Fecha última revisión:171030
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:170611
[St] Status:MEDLINE



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