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  1 / 284057 MEDLINE  
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[PMID]:25915696
[Au] Autor:Vial AC; Starks TJ; Parsons JT
[Ti] Título:Relative Efficiency of Field and Online Strategies in the Recruitment of HIV-Positive Men Who Have Sex With Men.
[So] Fuente:AIDS Educ Prev;27(2):103-11, 2015 Apr.
[Is] ISSN:1943-2755
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:Efforts to reach HIV-positive men who have sex with men (MSM) and link them to care must be expanded; however, finding and recruiting them remains a challenge. We compared the efficiency of three recruitment sources in reaching self-identified HIV-positive MSM with various characteristics. Relative to recruitment online and at clubs and bars, AIDS Service Organizations (ASOs) were significantly more efficient in reaching HIV-positive MSM in general. This was also true for those with specific characteristics of interest such as substance/stimulant use, and HIV-positive MSM who were racial/ethnic minorities. Both ASOs and online recruitment were more efficient than clubs and bars in reaching HIV-positive MSM not taking HIV medication. This was also the case for White HIV-positive MSM in general, and White HIV-positive MSM who used substances and stimulants. Online recruitment was also more efficient than clubs and bars in reaching HIV-positive MSM who were young across the board.
[Mh] Términos MeSH primario: Eficiencia Organizacional
Infecciones por VIH/terapia
Homosexualidad Masculina
Selección de Paciente
[Mh] Términos MeSH secundario: Adolescente
Adulto
Recolección de Datos
Grupos Étnicos
Grupo de Ascendencia Continental Europea
Infecciones por VIH/etnología
Humanos
Internet
Masculino
Grupos Minoritarios
Parejas Sexuales
Adulto Joven
[Pt] Tipo de publicación:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mes de ingreso:1507
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:150428
[St] Status:MEDLINE
[do] DOI:10.1521/aeap.2015.27.2.103


  2 / 284057 MEDLINE  
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[PMID]:25898044
[Au] Autor:Fouda GG; Cunningham CK; Permar SR
[Ad] Dirección:Department of Pediatrics, Duke University Medical Center, Durham, North Carolina2Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina.
[Ti] Título:Infant HIV-1 vaccines: supplementing strategies to reduce maternal-child transmission.
[So] Fuente:JAMA;313(15):1513-4, 2015 Apr 21.
[Is] ISSN:1538-3598
[Cp] País de publicación:United States
[La] Idioma:eng
[Mh] Términos MeSH primario: Vacunas contra el SIDA
Síndrome de Inmunodeficiencia Adquirida/transmisión
VIH-1
Transmisión Vertical de Enfermedad Infecciosa/prevención & control
[Mh] Términos MeSH secundario: Síndrome de Inmunodeficiencia Adquirida/prevención & control
Adulto
Femenino
Humanos
Lactante
Leche Humana/virología
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nombre de substancia:
0 (AIDS Vaccines)
[Em] Mes de ingreso:1505
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:150422
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2015.1382


  3 / 284057 MEDLINE  
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[PMID]:25162483
[Au] Autor:Anderson AM; Ross MW; Nyoni JE; McCurdy SA
[Ad] Dirección:a School of Public Health , University of Texas , Houston , TX 77225 , USA.
[Ti] Título:High prevalence of stigma-related abuse among a sample of men who have sex with men in Tanzania: implications for HIV prevention.
[So] Fuente:AIDS Care;27(1):63-70, 2015.
[Is] ISSN:1360-0451
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:In sub-Saharan Africa, the prevalence of stigma-related abuse and violence among men who have sex with men (MSM) and its potential impact on the HIV/AIDS epidemic is unknown. This study estimated the prevalence and source of violence and abuse among a sample of MSM in Tanzania and characterized the association between levels of violence and sexual and mental health variables. Data were taken from a larger study of 200 MSM in Tanzania. Frequency tabulations, bivariate analysis, and logistic regression were performed to describe the prevalence and source of abuse and to determine the association between levels of violence and sexual demographics and mental health variables. The MSM sample for this study was young (median age 23), somewhat educated with the majority having attained secondary school (80%) and mostly employed (60%). Verbal (48.5%) and moral (32.5%) abuses were the most predominant types of abuse among the sample and were mostly from people in the street and neighbors. Sexual abuse (30%) was mostly from partners, and physical violence (29.5%) was largely from people in the street. Participants in the high-violence level group had a significantly greater number of sexual partners, depression scores, and internalized homonegativity (IH) scores. IH predicted HIV infection and verbal abuse predicted IH.There is a need for an increased awareness of violence and abuse faced by MSM in Tanzania, as well as effective programs to specifically target the issue of violence among MSM, and its implication for mental health and for risky sexual behaviors and HIV transmission.
[Mh] Términos MeSH primario: Infecciones por VIH/prevención & control
Homosexualidad Masculina
Estereotipo
[Mh] Términos MeSH secundario: Adolescente
Adulto
Estudios Transversales
Infecciones por VIH/epidemiología
Conocimientos, Actitudes y Práctica en Salud
Humanos
Masculino
Mediana Edad
Prevalencia
Tanzanía/epidemiología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mes de ingreso:1503
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:141106
[St] Status:MEDLINE
[do] DOI:10.1080/09540121.2014.951597


  4 / 284057 MEDLINE  
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[PMID]:24977377
[Au] Autor:Yehia BR; Fleishman JA; Agwu AL; Metlay JP; Berry SA; Gebo KA; HIV Research Network
[Ad] Dirección:*Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; †Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA; ‡Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality, Rockville, MD; §Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; and ‖Department of Medicine, Massachusetts General Hospital, Boston, MA.
[Ti] Título:Health insurance coverage for persons in HIV care, 2006-2012.
[So] Fuente:J Acquir Immune Defic Syndr;67(1):102-6, 2014 Sep 1.
[Is] ISSN:1944-7884
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:We examined trends in health insurance coverage among 36,999 HIV-infected adults in care at 11 US HIV clinics between 2006 and 2012. Aggregate health insurance coverage was stable during this time. The proportions of patient-years with private, Medicaid, Medicare, and no insurance during this period were 15.9%, 35.7%, 20.1%, and 28.4%, respectively. Medicaid coverage was more prevalent among women than men, blacks, and Hispanics than whites, and individuals with injection drug use risk compared with other transmission risk factors. Hispanics and younger age groups were more likely to be uninsured than other racial/ethnic and older age groups, respectively.
[Mh] Términos MeSH primario: Infecciones por VIH/economía
Seguro de Salud/estadística & datos numéricos
Medicaid/estadística & datos numéricos
Pacientes no Asegurados/estadística & datos numéricos
Medicare/estadística & datos numéricos
[Mh] Términos MeSH secundario: Adolescente
Adulto
Anciano
Grupos Étnicos
Femenino
Infecciones por VIH/epidemiología
Humanos
Seguro de Salud/economía
Seguro de Salud/tendencias
Modelos Logísticos
Masculino
Medicaid/economía
Medicaid/tendencias
Medicare/economía
Mediana Edad
Estados Unidos/epidemiología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
[Em] Mes de ingreso:1501
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:140813
[St] Status:MEDLINE
[do] DOI:10.1097/QAI.0000000000000251


  5 / 284057 MEDLINE  
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[PMID]:24872131
[Au] Autor:Haines CF; Fleishman JA; Yehia BR; Berry SA; Moore RD; Bamford LP; Gebo KA; HIV Research Network
[Ad] Dirección:*Division of Infectious Diseases, Department of Medicine, The Johns Hopkins of Medicine, Baltimore, MD; †Agency for Healthcare Research and Quality (AHRQ); ‡Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and §Jonathan Lax Treatment Center, Philadelphia, PA.
[Ti] Título:Increase in CD4 count among new enrollees in HIV care in the modern antiretroviral therapy era.
[So] Fuente:J Acquir Immune Defic Syndr;67(1):84-90, 2014 Sep 1.
[Is] ISSN:1944-7884
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: Earlier HIV diagnosis and engagement in care improve outcomes and is cost effective, as a result, in 2006, the Centers for Disease Control and Prevention (CDC) revised the HIV-screening guidelines. We sought to determine whether the CD4 count (CD4) at presentation, a surrogate for time to presentation, increased during the study period. Our a priori hypothesis was that the CD4 at presentation increased during the study period, particularly after the CDC guideline revision. METHODS: We performed a retrospective cohort study and analyzed data from the HIV Research Network, a consortium of 18 US clinics caring for HIV-infected patients. HIV-infected adults (≥18 years old) newly presenting for care between 2003 and 2011 were included in this study. Multivariable linear regression examined associations with CD4 at enrollment. Calendar year was modeled as a linear spline with a change in slope at 2008, allowing determination of the mean change in CD4 per year during 2003-2007 and 2008-2011. RESULTS: Over 13,543 newly presenting subjects enrolled from 2003 to 2011. Median CD4 at enrollment rose from 285 to 317 cells per cubic millimeter between 2003-2007 and 2008-2011 (P < 0.001). After adjusting for age, race/ethnicity, gender, HIV risk factor, and clinic site, the mean increase in the CD4 count at presentation per year was 13.3 cells per cubic millimeter per year (95% confidence interval 6.4 to 20.1 cells per cubic millimeter per year) greater during 2008-2011 than during 2003-2007. CONCLUSIONS: We demonstrate a small, but statistically significant, increase in CD4 at presentation after the CDC guideline revision. More efforts are needed to decrease time to presentation to HIV care.
[Mh] Términos MeSH primario: Recuento de Linfocito CD4/estadística & datos numéricos
Infecciones por VIH/epidemiología
Infecciones por VIH/inmunología
VIH-1/aislamiento & purificación
[Mh] Términos MeSH secundario: Adulto
Antirretrovirales/administración & dosificación
Estudios de Cohortes
Femenino
Infecciones por VIH/quimioterapia
Infecciones por VIH/virología
Humanos
Modelos Lineales
Masculino
Mediana Edad
Análisis Multivariante
ARN Viral/sangre
Estudios Retrospectivos
Estados Unidos/epidemiología
[Pt] Tipo de publicación:JOURNAL ARTICLE; MULTICENTER STUDY; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
[Nm] Nombre de substancia:
0 (Anti-Retroviral Agents); 0 (RNA, Viral)
[Em] Mes de ingreso:1501
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:140813
[St] Status:MEDLINE
[do] DOI:10.1097/QAI.0000000000000228


  6 / 284057 MEDLINE  
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[PMID]:24556871
[Au] Autor:Adimora AA; Ramirez C; Schoenbach VJ; Cohen MS
[Ad] Dirección:aSchool of Medicine bUNC Gillings School of Global Public Health, The University of North Carolina, Chapel Hill, North Carolina, USA.
[Ti] Título:Policies and politics that promote HIV infection in the Southern United States.
[So] Fuente:AIDS;28(10):1393-7, 2014 Jun 19.
[Is] ISSN:1473-5571
[Cp] País de publicación:England
[La] Idioma:eng
[Mh] Términos MeSH primario: Infecciones por VIH/epidemiología
Política de Salud
Política
[Mh] Términos MeSH secundario: Accesibilidad a los Servicios de Salud
Humanos
Sudoeste de Estados Unidos/epidemiología
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mes de ingreso:1501
[Cu] Fecha actualización por clase:150726
[Lr] Fecha última revisión:150726
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:140606
[St] Status:MEDLINE
[do] DOI:10.1097/QAD.0000000000000225


  7 / 284057 MEDLINE  
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[PMID]:25919527
[Au] Autor:D'Onofrio G; O'Connor PG; Pantalon MV; Chawarski MC; Busch SH; Owens PH; Bernstein SL; Fiellin DA
[Ad] Dirección:Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut....
[Ti] Título:Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial.
[So] Fuente:JAMA;313(16):1636-44, 2015 Apr 28.
[Is] ISSN:1538-3598
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:IMPORTANCE: Opioid-dependent patients often use the emergency department (ED) for medical care. OBJECTIVE: To test the efficacy of 3 interventions for opioid dependence: (1) screening and referral to treatment (referral); (2) screening, brief intervention, and facilitated referral to community-based treatment services (brief intervention); and (3) screening, brief intervention, ED-initiated treatment with buprenorphine/naloxone, and referral to primary care for 10-week follow-up (buprenorphine). DESIGN, SETTING, AND PARTICIPANTS: A randomized clinical trial involving 329 opioid-dependent patients who were treated at an urban teaching hospital ED from April 7, 2009, through June 25, 2013. INTERVENTIONS: After screening, 104 patients were randomized to the referral group, 111 to the brief intervention group, and 114 to the buprenorphine treatment group. MAIN OUTCOMES AND MEASURES: Enrollment in and receiving addiction treatment 30 days after randomization was the primary outcome. Self-reported days of illicit opioid use, urine testing for illicit opioids, human immunodeficiency virus (HIV) risk, and use of addiction treatment services were the secondary outcomes. RESULTS: Seventy-eight percent of patients in the buprenorphine group (89 of 114 [95% CI, 70%-85%]) vs 37% in the referral group (38 of 102 [95% CI, 28%-47%]) and 45% in the brief intervention group (50 of 111 [95% CI, 36%-54%]) were engaged in addiction treatment on the 30th day after randomization (P < .001). The buprenorphine group reduced the number of days of illicit opioid use per week from 5.4 days (95% CI, 5.1-5.7) to 0.9 days (95% CI, 0.5-1.3) vs a reduction from 5.4 days (95% CI, 5.1-5.7) to 2.3 days (95% CI, 1.7-3.0) in the referral group and from 5.6 days (95% CI, 5.3-5.9) to 2.4 days (95% CI, 1.8-3.0) in the brief intervention group (P < .001 for both time and intervention effects; P = .02 for the interaction effect). The rates of urine samples that tested negative for opioids did not differ statistically across groups, with 53.8% (95% CI, 42%-65%) in the referral group, 42.9% (95% CI, 31%-55%) in the brief intervention group, and 57.6% (95% CI, 47%-68%) in the buprenorphine group (P = .17). There were no statistically significant differences in HIV risk across groups (P = .66). Eleven percent of patients in the buprenorphine group (95% CI, 6%-19%) used inpatient addiction treatment services, whereas 37% in the referral group (95% CI, 27%-48%) and 35% in the brief intervention group (95% CI, 25%-37%) used inpatient addiction treatment services (P < .001). CONCLUSIONS AND RELEVANCE: Among opioid-dependent patients, ED-initiated buprenorphine treatment vs brief intervention and referral significantly increased engagement in addiction treatment, reduced self-reported illicit opioid use, and decreased use of inpatient addiction treatment services but did not significantly decrease the rates of urine samples that tested positive for opioids or of HIV risk. These findings require replication in other centers before widespread adoption. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00913770.
[Mh] Términos MeSH primario: Buprenorfina/uso terapéutico
Antagonistas de Narcóticos/uso terapéutico
[Mh] Términos MeSH secundario: Adulto
Servicio de Urgencia en Hospital
Femenino
Infecciones por VIH/epidemiología
Servicios de Salud/utilización
Hospitales Escuela
Hospitales Urbanos
Humanos
Estudios de Intervención
Masculino
Naloxona/uso terapéutico
Trastornos Relacionados con Opioides/quimioterapia
Remisión y Consulta
Riesgo
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nombre de substancia:
0 (Narcotic Antagonists); 36B82AMQ7N (Naloxone); 40D3SCR4GZ (Buprenorphine)
[Em] Mes de ingreso:1505
[Cu] Fecha actualización por clase:150724
[Lr] Fecha última revisión:150724
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:150429
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2015.3474


  8 / 284057 MEDLINE  
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[PMID]:25825450
[Au] Autor:Scheepers C; Shrestha RK; Lambson BE; Jackson KJ; Wright IA; Naicker D; Goosen M; Berrie L; Ismail A; Garrett N; Abdool Karim Q; Abdool Karim SS; Moore PL; Travers SA; Morris L
[Ad] Dirección:Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Division of Virology and Communicable Disease Surveillance, School of Pathology, University of the Witwatersrand, Johannesburg ...
[Ti] Título:Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire.
[So] Fuente:J Immunol;194(9):4371-8, 2015 May 1.
[Is] ISSN:1550-6606
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:The human Ig repertoire is vast, producing billions of unique Abs from a limited number of germline Ig genes. The IgH V region (IGHV) is central to Ag binding and consists of 48 functional genes. In this study, we analyzed whether HIV-1-infected individuals who develop broadly neutralizing Abs show a distinctive germline IGHV profile. Using both 454 and Illumina technologies, we sequenced the IGHV repertoire of 28 HIV-infected South African women from the Centre for the AIDS Programme of Research in South Africa (CAPRISA) 002 and 004 cohorts, 13 of whom developed broadly neutralizing Abs. Of the 259 IGHV alleles identified in this study, approximately half were not found in the International Immunogenetics Database (IMGT). This included 85 entirely novel alleles and 38 alleles that matched rearranged sequences in non-IMGT databases. Analysis of the rearranged H chain V region genes of mAbs isolated from seven of these women, as well as previously isolated broadly neutralizing Abs from other donors, provided evidence that at least eight novel or non-IMGT alleles contributed to functional Abs. Importantly, we found that, despite a wide range in the number of IGHV alleles in each individual, including alleles used by known broadly neutralizing Abs, there were no significant differences in germline IGHV repertoires between individuals who do and do not develop broadly neutralizing Abs. This study reports novel IGHV repertoires and highlights the importance of a fully comprehensive Ig database for germline gene usage prediction. Furthermore, these data suggest a lack of genetic bias in broadly neutralizing Ab development in HIV-1 infection, with positive implications for HIV vaccine design.
[Mh] Términos MeSH primario: Anticuerpos Neutralizantes
Genes de Inmunoglobulinas
Células Germinativas/metabolismo
Anticuerpos Anti-VIH/genética
Anticuerpos Anti-VIH/inmunología
Infecciones por VIH/genética
Infecciones por VIH/inmunología
VIH-1/inmunología
[Mh] Términos MeSH secundario: Adulto
Grupo de Ascendencia Continental Africana/genética
Alelos
Femenino
Humanos
Cadenas Pesadas de Inmunoglobulina/genética
Región Variable de Inmunoglobulina/genética
Filogenia
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nombre de substancia:
0 (Antibodies, Neutralizing); 0 (HIV Antibodies); 0 (Immunoglobulin Heavy Chains); 0 (Immunoglobulin Variable Region)
[Em] Mes de ingreso:1506
[Cu] Fecha actualización por clase:150724
[Lr] Fecha última revisión:150724
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:150418
[St] Status:MEDLINE
[do] DOI:10.4049/jimmunol.1500118


  9 / 284057 MEDLINE  
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[PMID]:25072616
[Au] Autor:Koss CA; Natureeba P; Plenty A; Luwedde F; Mwesigwa J; Ades V; Charlebois ED; Clark TD; Achan J; Ruel T; Nzarubara B; Kamya MR; Havlir DV; Cohan D
[Ad] Dirección:*HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA; †Makerere University-University of California, San Francisco Research Collaboration, Kampala, Uganda; ‡Center for AIDS Prevention Studies, Department of Medicine, University of California, San Francisco, San Francisco, CA; §Department of Obstetrics and Gynecology, New York University, New York, NY; ‖Medical Research Council Unit, The Gambia; ¶Division of Infectious Diseases, Department of Pediatrics, University of California, San Francisco, San Francisco, CA; #Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda; and **Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA.
[Ti] Título:Risk factors for preterm birth among HIV-infected pregnant Ugandan women randomized to lopinavir/ritonavir- or efavirenz-based antiretroviral therapy.
[So] Fuente:J Acquir Immune Defic Syndr;67(2):128-35, 2014 Oct 1.
[Is] ISSN:1944-7884
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: Protease inhibitor-based antiretroviral therapy (ART) has been associated with preterm birth in some studies. We examined risk factors for preterm birth among women randomized to lopinavir/ritonavir (LPV/r)- or efavirenz (EFV)-based ART. METHODS: This was a planned secondary analysis of the PROMOTE-Pregnant Women and Infants Study, an open-label, randomized controlled trial comparing the risk of placental malaria among HIV-infected, ART-naive pregnant Ugandan women assigned to initiate LPV/r- or EFV-based ART at 12-28 weeks gestation. Gestational age was determined based on last menstrual period and ultrasound biometry. All women received bednets and trimethoprim-sulfamethoxazole. Stillbirths, spontaneous abortions, and multiple gestations were excluded from the primary analysis. Potential risk factors for preterm birth (<37 weeks gestation) were evaluated by univariate and multivariate logistic regression. RESULTS: Three hundred fifty-six women were included in this analysis. At enrollment, median gestational age was 21 weeks and median CD4 cell count was 368 cells per cubic millimeter. 14.7% of deliveries in the EFV arm and 16.2% in the LPV/r arm were preterm. Preterm birth was associated with gestational weight gain below 0.1 kg/week versus 0.1 kg/week or more [odds ratio (OR) = 2.49; 95% confidence interval (CI): 1.38 to 4.47; P = 0.003]. Neither ART regimen of LPV/r versus EFV (OR = 1.12; 95% CI: 0.63 to 2.00; P = 0.69) nor placental malaria (OR = 0.74; 95% CI: 0.38 to 1.44; P = 0.37) was associated with preterm birth. CONCLUSIONS: LPV/r was not associated with an increased risk of preterm birth compared with EFV. However, interventions are needed to address modifiable risk factors for preterm birth, such as nutritional status (ClinicalTrials.gov, NCT00993031).
[Mh] Términos MeSH primario: Fármacos Anti-VIH/efectos adversos
Fármacos Anti-VIH/uso terapéutico
Terapia Antirretroviral Altamente Activa/efectos adversos
Terapia Antirretroviral Altamente Activa/métodos
Infecciones por VIH/complicaciones
Infecciones por VIH/quimioterapia
Nacimiento Prematuro/epidemiología
[Mh] Términos MeSH secundario: Adolescente
Adulto
Benzoxazinas/efectos adversos
Benzoxazinas/uso terapéutico
Femenino
Humanos
Recién Nacido
Lopinavir/efectos adversos
Lopinavir/uso terapéutico
Masculino
Embarazo
Factores de Riesgo
Ritonavir/efectos adversos
Ritonavir/uso terapéutico
Uganda/epidemiología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nombre de substancia:
0 (Anti-HIV Agents); 0 (Benzoxazines); 2494G1JF75 (Lopinavir); JE6H2O27P8 (efavirenz); O3J8G9O825 (Ritonavir)
[Em] Mes de ingreso:1501
[Cu] Fecha actualización por clase:150724
[Lr] Fecha última revisión:150724
[Sb] Subgrupo de revista:IM; X
[Da] Fecha de ingreso para procesamiento:140912
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1097/QAI.0000000000000281


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[PMID]:24496568
[Au] Autor:White JM; Reisner SL; Dunham E; Mimiaga MJ
[Ad] Dirección:The Fenway Institute, Fenway Health, Boston, MA, USA, jwhite@fenwayhealth.org.
[Ti] Título:Race-based sexual preferences in a sample of online profiles of urban men seeking sex with men.
[So] Fuente:J Urban Health;91(4):768-75, 2014 Aug.
[Is] ISSN:1468-2869
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:Race-based sexual preferences in the online profiles of men who have sex with men (MSM) may be relevant for understanding the sexual health of this population, including racial/ethnic disparities in HIV infection. In October 2011, a content analysis was conducted of the profiles of Boston-area members of a racially diverse website for MSM. The present analysis formatively examined the use of demographic and partner selection criteria by race/ethnicity appearing in the profiles of men who indicated race-based partner preferences (n = 89). Latino men were the most frequently preferred race (54 %), followed by White (52 %), Black (48 %), and Asian (12 %) men. In separate multivariable models adjusted for age and HIV status disclosure, wanting low-risk foreplay was associated with a preference for White men (aOR) = 4.27; 95 % CI = 1.70-10.75; p = 0.002), while wanting group sex was associated with a preference for Black (OR = 2.28; 95 % CI = 1.08-4.81; p = 0.03) and Latino men (OR = 2.56; 95 % CI = 1.25-5.23; p = 0.01). Future studies are needed to replicate findings in larger online samples. Mixed-methods research should explore how racial and behavioral preferences impact the sexual mixing patterns and health of MSM online in urban areas.
[Mh] Términos MeSH primario: Grupos Étnicos/estadística & datos numéricos
Homosexualidad Masculina/etnología
Homosexualidad Masculina/estadística & datos numéricos
Conducta Sexual/etnología
Conducta Sexual/estadística & datos numéricos
Parejas Sexuales
[Mh] Términos MeSH secundario: Adolescente
Adulto
Afroamericanos/estadística & datos numéricos
Factores de Edad
Anciano
Americanos Asiáticos/estadística & datos numéricos
Boston/epidemiología
Grupo de Ascendencia Continental Europea/estadística & datos numéricos
Infecciones por VIH/epidemiología
Hispanoamericanos/estadística & datos numéricos
Humanos
Masculino
Mediana Edad
Asunción de Riesgos
Factores Socioeconómicos
Adulto Joven
[Pt] Tipo de publicación:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mes de ingreso:1505
[Cu] Fecha actualización por clase:150724
[Lr] Fecha última revisión:150724
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140816
[St] Status:MEDLINE
[do] DOI:10.1007/s11524-013-9853-4



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