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  1 / 276759 MEDLINE  
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[PMID]:25088574
[Au] Autor:Oga M; Brou H; Dago-Akribi H; Coffie P; Amani-Bossé C; Ekouévi D; Yapo V; Menan H; Ndondoki C; Timité-Konan M; Leroy V
[Ad] Dirección:a Sociologist at the Pacci Program Site ANRS , Abidjan, Côte d'Ivoire.
[Ti] Título:Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire, Significations pour la couverture du diagnostic pédiatrique.
[So] Fuente:SAHARA J;11(1):148-57, 2014.
[Is] ISSN:1813-4424
[Cp] País de publicación:South Africa
[La] Idioma:eng
[Ab] Resumen:UNLABELLED: Résumé Problème: Le dépistage VIH chez les enfants a rarement été au centre des préoccupations des chercheurs. Quand le dépistage pédiatrique a retenu l'attention, cela a été pour éclairer seulement sur les performances diagnostiques en ignorant même que le test pédiatrique comme bien d'autres peut s'accepter ou se refuser. Cet article met au cÅ“ur de son analyse les raisons qui peuvent expliquer qu'on accepte ou qu'on refuse de faire dépister son enfant. Objectif: Etudier chez les parents, les mères, les facteurs explicatifs de l'acceptabilité du test VIH des nourrissons de moins de six mois. Méthodes: Entretien semi-directif à passages répétés avec les parents de nourrissons de moins de six mois dans les formations sanitaires pour la pesée/vaccination et les consultations pédiatriques avec proposition systématique d'un test VIH pour leur nourrisson. Résultats: Nous retenons que la réalisation effective du test pédiatrique du VIH chez le nourrisson repose sur trois éléments. Primo, le personnel de santé par son discours (qui dénote de ses connaissances et perceptions même sur l'infection) orienté vers les mères influence leur acceptation ou non du test. Secundo, la mère qui par ses connaissances et perceptions même sur le VIH, dont le statut particulier, l'impression de bien-être chez elle et son enfant influence toute réalisation du test pédiatrique VIH. Tertio, l'environnement conjugal de la mère, particulièrement caractérisé par les rapports au sein du couple, sur la facilité de parler du test VIH et sa réalisation chez les deux parents ou chez la mère seulement sont autant de facteurs qui influencent la réalisation effective du dépistage du VIH chez l'enfant. Le principe préventif du VIH, et le désir de faire tester l'enfant ne suffisent pas à eux seuls pour aboutir à sa réalisation effective, selon certaines mères confrontées au refus du conjoint. A l'opposé, les autres mères refusant la réalisation du test pédiatrique disent s'y opposer ; bien entendu, même dans le cas où le conjoint l'accepterait. DISCUSSION: Les mères sont les principales mises en cause et craignent les réprimandes et la stigmatisation. Le père, le conjoint peut être un obstacle, quand il s'oppose au test VIH du nourrisson, ou devenir le facilitateur de sa réalisation s'il est convaincu. Le positionnement du père demeure donc essentiel dans la question de l'acceptabilité du VIH pédiatrique. Les mères en ont conscience et présagent des difficultés à faire dépister ou non les enfants sans avis préalable du conjoint à la fois père, et chef de famille. CONCLUSION: La question du dépistage pédiatrique du VIH, au terme de notre analyse, met en face trois éléments qui exigent une gestion globale pour assurer une couverture effective. Ces trois éléments n'existeraient pas sans s'influencer, donc ils sont constamment en interaction et empêchent ou favorisent la réalisation ou non du test pédiatrique. Aussi, dans une intention d'aboutir à une couverture effective du dépistage VIH des nourrissons, faut-il tenir compte d'une gestion harmonieuse de ces trois éléments: La première, la mère seule (avec ses connaissances, ses perceptions), son environnement conjugal (de proposition du test intégrant 1- l'époux et / ou père de l'enfant avec ses perceptions et connaissances sur l'infection 2- la facilité de parler du test et sa réalisation chez les deux ou un des parents, la mère) et les connaissances, attitudes et pratiques du personnel de l'établissement sanitaire sur l'infection du VIH. Recommandations: Nos recommandations proposent une redéfinition de l'approche du VIH/sida vers des familles exposées au VIH et une intégration plus accentuée du père facilitant leur propre acceptation du test VIH et celle de leur enfant.
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM; X
[St] Status:In-Data-Review
[do] DOI:10.1080/17290376.2014.938101


  2 / 276759 MEDLINE  
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[PMID]:25380268
[Au] Autor:Sanon A; Berthé A; Traoré I; Ouédraogo S; Etoudji A; Konaté I; Thiénou JR; Konaté B; Barbari A; Soulama A; Nagot N
[Ti] Título:[Governance of HIV/AIDS organizations in Bobo-Dioulasso (Burkina Faso)].
[Ti] Título:La gouvernance au sein des organisations de lutte contre le VIH à Bobo-Dioulasso (Burkina Faso)..
[So] Fuente:Sante Publique;26(4):531-9, 2014 Jul-Aug.
[Is] ISSN:0995-3914
[Cp] País de publicación:France
[La] Idioma:fre
[Ab] Resumen:INTRODUCTION: Although HIV/AIDS organizations continue to play a major role in the fight against pandemic HIV infections, they are still faced with enormous governance challenges that impair their operations / interventions and their sustainability. The objective of this study was to develop an inventory of the quality of governance within HIV/AIDS organizations in Bobo-Dioulasso. METHODS: This qualitative research was conducted in 40 organizations from Bobo-Dioulasso. Qualitative data were collected over a 45-day period using an interview guide. Thematic analysis of the data was performed and the results were reported. RESULTS: Although all 40 organizations had established good governance mechanisms, only fifteen complied with the major rules of democratic functioning and the roles of the various bodies. The majority of these organizations (29/40) ignored many democratic rules. The number of members required for the Executive Board was not met in 29/40 organizations resulting in monopolization of decision-making by a handful of people. Technical and financial reports were not published, resulting in limited access to information on the organization's activities. Gender equality also constituted a weakness. DISCUSSION: Application of good governance principles was limited in these organizations. Organization members, leaders and technical and financial partners must reinforce good governance efforts in order to improve good governance in these organizations.
[Pt] Tipo de publicación:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mes de ingreso:1411
[Sb] Subgrupo de revista:IM
[St] Status:In-Process


  3 / 276759 MEDLINE  
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[PMID]:24950612
[Au] Autor:Alastrué Loscos I; Díaz Franco A; Santos Rubio C; Juan Corrons A
[Ad] Dirección:Centro de Información y Prevención del Sida de Valencia, Centro de Salud Pública de Valencia, Dirección General de Salud Pública, Conselleria de Sanidad, Valencia, España. Electronic address: alastrue_ign@gva.es....
[Ti] Título:[Are STI/HIV centers effective in reducing late HIV diagnosis?].
[Ti] Título:¿Son efectivos los centros específicos de VIH/ITS para disminuir el retraso del diagnóstico en la infección por el virus de la inmunodeficiencia humana?.
[So] Fuente:Enferm Infecc Microbiol Clin;32(10):689-90, 2014 Dec.
[Is] ISSN:1578-1852
[Cp] País de publicación:Spain
[La] Idioma:spa
[Pt] Tipo de publicación:LETTER
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review


  4 / 276759 MEDLINE  
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[PMID]:24365474
[Au] Autor:Messina FA; Negroni R; Maiolo EI; Arechavala A; Villafañe MF; Santiso G; Bianchi M; Walker L; Corti M
[Ad] Dirección:Unidad de Micología, Hospital de Infecciosas F J Muñiz, Ciudad Autónoma de Buenos Aires, Argentina. Electronic address: fmessina35@gmail.com....
[Ti] Título:[Cryptococcal meningitis in patients with diabetes and AIDS].
[Ti] Título:Criptococosis meníngea en pacientes con diabetes y sida..
[So] Fuente:Enferm Infecc Microbiol Clin;32(10):643-6, 2014 Dec.
[Is] ISSN:1578-1852
[Cp] País de publicación:Spain
[La] Idioma:spa
[Ab] Resumen:INTRODUCTION: Cryptococcal meningitis is a severe AIDS-related infectious disease, with a high mortality rate. Diabetes mellitus (DM) is a metabolic disorder very common worldwide. Infectious diseases in diabetic patients are always more severe than in non-diabetic ones. The aim of this study was to compare the outcome of a group of HIV-positive patients with DM and cryptococcal meningitis with a similar group HIV-positive patients with cryptococcal meningitis, but without DM. MATERIAL AND METHODS: A total of 182 clinical records of HIV-positive patients suffering cryptococcal meningitis were reviewed, and 28 of them with similar clinical and epidemiological characteristics, were chosen. They included 14 patients with DM (group A) and the remaining 14 who did not suffer this metabolic disorder (group B). RESULTS: Only 21.4% (3/14 cases) of group A patients had negative CSF cultures after 10 weeks of treatment. In group B patients, 78.5% (11/14 cases) achieved negative CSF cultures before 10 weeks. A higher overall mortality rate was observed in the diabetic patients (85.7%, 12/14 cases) than in the non-diabetic group (21.4%, 3/14 cases). All CSF isolates were identified as Cryptococcus neoformans, and all strains were susceptible in vitro to amphotericin B and fluconazole. CONCLUSIONS: Cryptococcal meningitis in diabetic patients was associated with a poor clinical outcome and a high mortality rate. A longer treatment induction period is suggested in order to improve the outcome of cryptococcal meningitis in diabetic patients.
[Pt] Tipo de publicación:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review


  5 / 276759 MEDLINE  
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[PMID]:24837404
[Au] Autor:Espada JP; Guillén-Riquelme A; Morales A; Orgilés M; Sierra JC
[Ad] Dirección:Departamento de Psicología de la Salud, Universidad Miguel Hernández, Elche, Alicante, España. Electronic address: jpespada@umh.es....
[Ti] Título:[Validation of an HIV and other sexually transmitted infections knowledge scale in an adolescent population].
[Ti] Título:Validación de una escala de conocimiento sobre el VIH y otras infecciones de transmisión sexual en población adolescente..
[So] Fuente:Aten Primaria;46(10):558-64, 2014 Dec.
[Is] ISSN:1578-1275
[Cp] País de publicación:Spain
[La] Idioma:spa
[Ab] Resumen:OBJECTIVE: The objective of this research is to determine the validity and reliability of a questionnaire designed to specifically assess the knowledge of HIV and other sexually transmitted infections in a Spanish adolescent population. DESIGN: Cross-sectional study for the validation of a questionnaire. LOCATION: A total of 17 schools in five Spanish provinces. PARTICIPANTS: A total of 1,570 adolescent schoolchildren between 13 and 17 years old. INTERVENTION: A pool of 40 items relating to knowledge about HIV and other sexually transmitted infections was established. This pool was analyzed by an expert panel. It was then administered to a pilot group with the same demographic characteristics of the sample, to ensure comprehension. MAIN MEASUREMENT: Item analysis, internal consistency, test/retest and exploratory factorial analysis. RESULTS: A factor analysis was performed, in which five factors that explained 46% of the total variance were retained: general knowledge about HIV, condom as a protective method, routes of HIV transmission, the prevention of HIV, and other sexually transmitted infections. Reliability measures ranged from 0.66 to 0.88. The test-retest correlation was 0.59. There were gender differences in the knowledge of infections. CONCLUSIONS: These factors have adequate internal consistency and acceptable test-retest correlation. Theoretically, these factors fit properly with the content of the items. The factors have a moderate relationship, indicating that a high degree of knowledge about an aspect, but not a guarantee of general knowledge. The availability of a questionnaire to assess knowledge of sexually transmitted infections is helpful to evaluate prevention programs.
[Pt] Tipo de publicación:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review


  6 / 276759 MEDLINE  
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[PMID]:24663014
[Au] Autor:Bhatt NB; Barau C; Amin A; Baudin E; Meggi B; Silva C; Furlan V; Grinsztejn B; Barrail-Tran A; Bonnet M; Taburet AM; ANRS 12146-CARINEMO Study Group
[Ad] Dirección:Instituto Nacional de Saúde, Ministério da Saúde, Maputo, Mozambique Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil....
[Ti] Título:Pharmacokinetics of rifampin and isoniazid in tuberculosis-HIV-coinfected patients receiving nevirapine- or efavirenz-based antiretroviral treatment.
[So] Fuente:Antimicrob Agents Chemother;58(6):3182-90, 2014 Jun.
[Is] ISSN:1098-6596
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadministration of nonnucleoside reverse transcriptase inhibitor-based HIV antiretroviral therapy in HIV-tuberculosis-coinfected patients in Mozambique. Thirty-eight patients on antituberculosis therapy based on rifampin and isoniazid participated in the substudy (57.9% males; median age, 33 years; median weight, 51.9 kg; median CD4(+) T cell count, 104 cells/µl; median HIV-1 RNA load, 5.5 log copies/ml). The daily doses of rifampin and isoniazid were 10 and 5 mg/kg of body weight, respectively. Twenty-one patients received 200 mg of nevirapine twice a day (b.i.d.), and 17 patients received 600 mg of efavirenz once a day (q.d.) in combination with lamivudine and stavudine from day 1 until the end of the study. Blood samples were collected at regular time-dosing intervals after morning administration of a fixed-dose combination of rifampin and isoniazid. When rifampin was administered alone, the median maximum concentration of drug in serum (Cmax) and the area under the concentration-time curve (AUC) at steady state were 6.59 mg/liter (range, 2.70 to 14.07 mg/liter) and 27.69 mg · h/liter (range, 11.41 to 109.75 mg · h/liter), respectively. Concentrations remained unchanged when rifampin was coadministered with nevirapine or efavirenz. When isoniazid was administered alone, the median isoniazid Cmax and AUC at steady state were 5.08 mg/liter (range, 1.26 to 11.51 mg/liter) and 20.92 mg · h/liter (range, 7.73 to 56.95 mg · h/liter), respectively. Concentrations remained unchanged when isoniazid was coadministered with nevirapine; however, a 29% decrease in the isoniazid AUC was observed when isoniazid was combined with efavirenz. The pharmacokinetic parameters of rifampin and isoniazid when coadministered with nevirapine or efavirenz were not altered to a clinically significant extent in these severely immunosuppressed HIV-infected patients. Patients experienced favorable clinical outcomes. (This study has been registered at ClinicalTrials.gov under registration no. NCT00495326.).
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mes de ingreso:1407
[Cu] Fecha actualización por clase:141201
[Lr] Fecha última revisión:141201
[Sb] Subgrupo de revista:IM
[Cl] Clinical Trial:ClinicalTrial
[St] Status:In-Process
[do] DOI:10.1128/AAC.02379-13


  7 / 276759 MEDLINE  
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[PMID]:24556267
[Au] Autor:Cecchini D; Martinez M; Morganti L; Rodriguez C
[Ad] Dirección:Unidad de Infectología, Hospital General de Agudos Cosme Argerich, Buenos Aires, Argentina. Electronic address: diegocec@gmail.com....
[Ti] Título:[Use of raltegravir in pregnant HIV-1 infected women: Experience in different clinical scenarios].
[Ti] Título:Uso de raltegravir en embarazadas infectadas por VIH-1: experiencia en diferentes escenarios clínicos..
[So] Fuente:Enferm Infecc Microbiol Clin;32(9):616-8, 2014 Nov.
[Is] ISSN:1578-1852
[Cp] País de publicación:Spain
[La] Idioma:spa
[Pt] Tipo de publicación:LETTER
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review


  8 / 276759 MEDLINE  
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[PMID]:25438379
[Au] Autor:Nau JY
[Ti] Título:[In Process Citation].
[Ti] Título:Sida: comment le VIH-1 a-t-il pu diffuser en silence pendant plus d'un demi-siècle?.
[So] Fuente:Rev Med Suisse;10(446):1938-9, 2014 Oct 15.
[Is] ISSN:1660-9379
[Cp] País de publicación:Switzerland
[La] Idioma:fre
[Pt] Tipo de publicación:NEWS
[Em] Mes de ingreso:1412
[Sb] Subgrupo de revista:IM
[St] Status:In-Process


  9 / 276759 MEDLINE  
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[PMID]:25426196
[Au] Autor:El Benaye J; Nihal B; Hicham J; Mohamed E
[Ad] Dirección:Service de Dermatologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc....
[Ti] Título:[Seven hours for effective and safe desensitization in HIV-positive patients intolerant to cotrimoxazole].
[Ti] Título:Sept heures pour une désensibilisation efficace et sans risque chez les patients VIH positifs intolérants au cotrimoxazole..
[So] Fuente:Pan Afr Med J;18:238, 2014.
[Is] ISSN:1937-8688
[Cp] País de publicación:Uganda
[La] Idioma:fre
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1411
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review
[do] DOI:10.11604/pamj.2014.18.238.4820


  10 / 276759 MEDLINE  
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[PMID]:25281479
[Au] Autor:Gonfrier G; Delotte J; Chevallier A; Giordanengo V
[Ad] Dirección:Laboratoire de virologie, hôpital Archet 2, centre hospitalier universitaire de Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice cedex 3, France; Inserm, U1065, centre méditerranéen de médecine moléculaire, C3M, toxines microbiennes dans la relation hôte pathogènes, 151, route de Saint-An...
[Ti] Título:[Distribution of human papillomavirus genotypes amongst HIV-negative and HIV-positive women diagnosed with ASC-US cytology. Preliminary data of a local retrospective study].
[Ti] Título:Répartition des génotypes de papillomavirus humain dans les frottis ASC-US de patientes infectées ou non par le VIH-1. Résultats préliminaires d'une enquête rétrospective locale..
[So] Fuente:Gynecol Obstet Fertil;42(10):692-5, 2014 Oct.
[Is] ISSN:1769-6682
[Cp] País de publicación:France
[La] Idioma:fre
[Ab] Resumen:OBJECTIVES: Analysis of the distribution of human papillomavirus (HPV) genotypes amongst HIV-negative and HIV-positive women diagnosed with atypical squamous cells of undetermined significance (ASC-US). PATIENTS AND METHODS: We performed a retrospective study of HPV genotype distribution in 313 ASC-US Pap smears from women who consulted at the University Hospital of Nice between 2008 and 2012. HPV genotyping results, conducted on PapilloCheck(®) HPV DNA Chip, and information on the status of HIV patients were retrospectively collected. The odds ratio were calculated by logistic regression. RESULTS: In co-infected HIV/HPV women we observed a low prevalence of HPV16, a high prevalence of oncogenic HPV low risk and a high prevalence of HPV 68 compared to non-co-infected women. By grouping HPV HR based on their prevalence in cervical cancer of the uterus and their genetic proximity we observe that HPV 18, 45, 68 (the "alpha-7") are 7.4 times more represented (CI95 [2.48 to 22.35]) than HPV 16, 31, 33, 52, 58 (the "alpha-9") in the population of women co-infected with HIV. DISCUSSION AND CONCLUSION: Given that HPV "alpha-7" are responsible for 46.3% of adenocarcinomas, the high prevalence of these HPV found in ASC-US Pap smears of co-infected women should be put in relation with the highest prevalence of glandular abnormalities found in this population. HPV genotyping could become an essential tool for gynecological care for HIV positive women.
[Pt] Tipo de publicación:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mes de ingreso:1410
[Sb] Subgrupo de revista:IM
[St] Status:In-Process



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