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[PMID]:25184023
[Au] Autor:Mbopi-Keou FX; Voundi EV; Kalla GC; Emah I; Angwafo F; Muna W
[Ad] Dirección:Faculty of Medicine & Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon ; National Public Health Laboratory, Ministry of Public Health, Yaounde, Cameroon....
[Ti] Título:[Factors influencing initiation of antiretroviral treatment for people living with HIV in approved HIV treatment centres of Bamenda and Bertoua in Cameroon].
[Ti] Título:Facteurs influençant l'initiation au traitement antirétroviral des personnes vivant avec le VIH dans les Centres de Traitement Agréés de Bamenda et de Bertoua au Cameroun..
[So] Fuente:Pan Afr Med J;17:6, 2014.
[Is] ISSN:1937-8688
[Cp] País de publicación:Uganda
[La] Idioma:fre
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[St] Status:In-Data-Review
[do] DOI:10.11604/pamj.2014.17.6.3221


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[PMID]:24919691
[Au] Autor:Van Niekerk E; Autran CA; Nel DG; Kirsten GF; Blaauw R; Bode L
[Ad] Dirección:Division of Human Nutrition and evettev@sun.ac.za....
[Ti] Título:Human milk oligosaccharides differ between HIV-infected and HIV-uninfected mothers and are related to necrotizing enterocolitis incidence in their preterm very-low-birth-weight infants.
[So] Fuente:J Nutr;144(8):1227-33, 2014 Aug.
[Is] ISSN:1541-6100
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:The heavy burden of maternal HIV infection has resulted in a high prevalence of premature birth and associated necrotizing enterocolitis (NEC). Human milk oligosaccharides (HMOs) were recently associated with HIV infection and transmission through breastfeeding and were also shown to reduce NEC in an animal model, particularly the HMO disialyllacto-N-tetraose (DSLNT). The primary aim of this study was to verify differences in HMO composition between HIV-infected and HIV-uninfected women. The secondary aim was to assess whether the HMO composition in the milk of mothers whose infants were diagnosed with NEC differs from that of mothers whose infants did not develop NEC. This study forms part of a larger clinical trial conducted at the Tygerberg Children's Hospital, Cape Town, South Africa, which recruited HIV-infected and HIV-uninfected mothers and their preterm infants (<34 wk gestation; ≥500 and ≤1250 g). Eighty-two mother-infant pairs were selected for the substudy. Mother-infant pairs were stratified according to the mother's HIV (infected/uninfected) and secretor status (secretor/nonsecretor). HMOs in 4- and 28-d postpartum milk samples were analyzed by HPLC and compared between groups. Our results confirm previous reports that HIV-infected mothers have higher relative abundances of 3'-sialyllactose in their milk compared with HIV-uninfected mothers (10.7% vs. 6.8%; P < 0.01). Most intriguingly, the data also indicated that low concentrations of DSLNT in the 4-d milk samples in the mother's milk increased the infant's risk of NEC (200 ± 126 vs. 345 ± 186 µg/mL; P < 0.05), which is in accordance with results from previously published animal studies and warrants further investigation. This trial was registered at clinicaltrials.gov as NCT01868737.
[Mh] Términos MeSH primario: Enterocolitis Necrotizante/epidemiología
Infecciones por VIH/metabolismo
Leche Humana/química
Oligosacáridos/análisis
Nacimiento Prematuro/epidemiología
[Mh] Términos MeSH secundario: Adulto
Lactancia Materna
Enterocolitis Necrotizante/etiología
Femenino
Infecciones por VIH/complicaciones
Humanos
Incidencia
Prematuro/metabolismo
Recién Nacido de muy Bajo Peso/metabolismo
Masculino
Madres
Embarazo
Nacimiento Prematuro/etiología
Ensayos Clínicos Controlados Aleatorios como Asunto
Sudáfrica
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nombre de substancia:
0 (3'-sialyllactose); 0 (Oligosaccharides); 0 (disialyllacto-N-tetraose)
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140719
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.3945/jn.113.187799


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[PMID]:24957052
[Au] Autor:Tadesse WT; Mekonnen AB; Tesfaye WH; Tadesse YT
[Ad] Dirección:Department of Pharmacology, School of Medicine, Addis Ababa Science & Technology University, Addis Ababa, Ethiopia. mail2wondm@gmail.com.
[Ti] Título:Self-reported adverse drug reactions and their influence on highly active antiretroviral therapy in HIV infected patients: a cross sectional study.
[So] Fuente:BMC Pharmacol Toxicol;15:32, 2014.
[Is] ISSN:2050-6511
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: Patients on antiretroviral therapy have higher risk of developing adverse drug reactions (ADRs). The impact of ADRs on treatment adherence, treatment outcomes and future treatment options is quiet considerable. Thus, the purpose of this study was to describe the common self-reported ADRs and their impact on antiretroviral treatment. METHODS: Cross-sectional study was conducted at antiretroviral therapy (ART) clinic of Gondar University Hospital. Semi-structured interview questionnaire was used to extract self-reported ADRs, socio-demographic, and psycho-social variables. Variables related to antiretroviral medication, laboratory values and treatment changes were obtained from medical charts. Chi-square and odds ratio with 95% confidence interval were used to determine the associations of dependent variables. RESULT: A total of 384 participants were enrolled. At least one adverse drug reaction was reported by 345 (89.8%) study participants and the mean number of ADRs reported was 3.7 (±0.2). The most frequently reported ADRs were nausea (56.5%) and headache (54.9%). About 114 (31.0%) participants considered antiretroviral therapy to be unsuccessful if ADRs occurred and only 10 (2.6%) decided to skip doses as ADRs were encountered. Based on chart review, treatment was changed for 78 (20.3%) patients and from which 79% were due to documented ADRs (p = 0.00). Among them, CNS symptoms (27.4%) and anemia (16.1%) were responsible for the majority of changes. Around four percent of patients were non-adherent to ART. Non-adhered participants and those on treatment changes were not statistically associated with self-reported ADRs. Only unemployment status (AOR = 1.76 (1.15 - 2.70), p = 0.01) and ADR duration of less than one month (AOR = 1.95 (1.28-2.98), p = 0.001) were significantly associated with self-reported adverse effects of three or more in the multivariate analysis. CONCLUSION: Self-reported ADRs to antiretroviral therapy are quite common. More of the reactions were of short lasting and their impact on adherence and treatment change were less likely. However, documented ADRs were the most prevalent reasons for ART switch. Moreover, the level of unemployment was a strong predictor of self-reported ADRs.
[Mh] Términos MeSH primario: Terapia Antirretroviral Altamente Activa/efectos adversos
Infecciones por VIH/quimioterapia
[Mh] Términos MeSH secundario: Adulto
Estudios Transversales
Etiopía/epidemiología
Femenino
Infecciones por VIH/epidemiología
Infecciones por VIH/psicología
Humanos
Masculino
Cumplimiento de la Medicación/estadística & datos numéricos
Autoinforme
Aislamiento Social
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140705
[St] Status:MEDLINE
[do] DOI:10.1186/2050-6511-15-32


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[PMID]:24982536
[Au] Autor:Cohen SM; Gray KM; Ocfemia MC; Johnson AS; Hall HI
[Ad] Dirección:Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA....
[Ti] Título:The status of the National HIV Surveillance System, United States, 2013.
[So] Fuente:Public Health Rep;129(4):335-41, 2014 Jul-Aug.
[Is] ISSN:1468-2877
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:The burden of HIV disease in the United States is monitored by using a comprehensive surveillance system. Data from this system are used at the federal, state, and local levels to plan, implement, and evaluate public health policies and programs. Implementation of HIV reporting has differed by area, and for the first time in early 2013, estimated data on diagnosed HIV infection were available from all 50 states, the District of Columbia, and six U.S. dependent areas. The newly available data for the entire U.S. as well as several other key changes to the surveillance system support the need to provide an updated summary of the status of the National HIV Surveillance System.
[Mh] Términos MeSH primario: Infecciones por VIH/epidemiología
Vigilancia en Salud Pública/métodos
[Mh] Términos MeSH secundario: Recuento de Linfocito CD4
Seguridad Computacional
Confidencialidad
Femenino
Mapeo Geográfico
Infecciones por VIH/mortalidad
Humanos
Incidencia
Embarazo
Efectos Tardíos de la Exposición Prenatal/epidemiología
Prevalencia
Índice de Severidad de la Enfermedad
Estados Unidos/epidemiología
Carga Viral
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:140701
[St] Status:MEDLINE


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[PMID]:24982535
[Au] Autor:Mdodo R; Thomas PE; Walker A; Chavez P; Ethridge S; Oraka E; Sutton MY
[Ad] Dirección:Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA....
[Ti] Título:Rapid HIV testing at gay pride events to reach previously untested MSM: U.S., 2009-2010.
[So] Fuente:Public Health Rep;129(4):328-34, 2014 Jul-Aug.
[Is] ISSN:1468-2877
[Cp] País de publicación:United States
[La] Idioma:eng
[Ab] Resumen:We offered rapid HIV testing at social events frequented by young men who have sex with men (MSM), a group disproportionately affected by the HIV epidemic. We tested 1,312 MSM; of those MSM, 1,072 (81.7%) reported HIV testing history. Of those reporting HIV testing history, 550 (51.3%) were non-Hispanic black and 404 (37.7%) were aged <25 years. One hundred twenty-eight (11.9%) had never tested for HIV; 77 (7.2%) were preliminarily positive, with 15 (19.5%) being first-time testers. Factors associated with no previous HIV test included young age (13-24 years) (adjusted odds ratio [AOR] = 3.5, 95% confidence interval [CI] 1.9, 6.5) and non-Hispanic black (AOR=3.2, 95% CI 1.6, 6.4) or Hispanic (AOR=2.8, 95% CI 1.2, 6.3) race/ethnicity. HIV testing at Gay Pride events reaches young, previously untested MSM. This venue-based HIV testing approach at nonclinical sociocultural events is an additional strategy for HIV prevention goals to increase the number of people aware of their HIV infection with subsequent linkage to HIV care.
[Mh] Términos MeSH primario: Diagnóstico Precoz
Infecciones por VIH/diagnóstico
Infecciones por VIH/etnología
Vacaciones y Feriados
Homosexualidad Masculina
[Mh] Términos MeSH secundario: Adolescente
Adulto
Factores de Edad
Humanos
Masculino
Distribución Espacial de la Población
Factores de Riesgo
Conducta Sexual
Abuso de Sustancias por Vía Intravenosa/epidemiología
Estados Unidos/epidemiología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:140701
[St] Status:MEDLINE


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[PMID]:24982533
[Au] Autor:Valdiserri RO
[Ad] Dirección:Ronald Valdiserri is Deputy Assistant Secretary for Health, Infectious Diseases and Director of the Office of HIV/AIDS and Infectious Disease Policy, U.S. Department of Health and Human Services in Washington, D.C.
[Ti] Título:Improving outcomes along the HIV care continuum: paying careful attention to the non-biologic determinants of health.
[So] Fuente:Public Health Rep;129(4):319-21, 2014 Jul-Aug.
[Is] ISSN:1468-2877
[Cp] País de publicación:United States
[La] Idioma:eng
[Mh] Términos MeSH primario: Continuidad de la Atención al Paciente/organización & administración
Infecciones por VIH/terapia
Determinantes Sociales de la Salud
[Mh] Términos MeSH secundario: Antirretrovirales/uso terapéutico
Centers for Disease Control and Prevention (U.S.)
Infecciones por VIH/etnología
Investigación sobre Servicios de Salud
Humanos
Evaluación de Procesos y Resultados (Atención de Salud)
Factores de Riesgo
Conducta Sexual
Factores Socioeconómicos
Estados Unidos
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Nm] Nombre de substancia:
0 (Anti-Retroviral Agents)
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:AIM; IM
[Da] Fecha de ingreso para procesamiento:140701
[St] Status:MEDLINE


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[PMID]:24923376
[Au] Autor:Wiwanitkit S; Wiwanitkit V
[Ad] Dirección:Wiwanitkit House, Bangkhae, Bangkok, Thailand.
[Ti] Título:Dyslipidemia among HIV-infected patients.
[So] Fuente:Ann Afr Med;13(3):142, 2014 Jul-Sep.
[Is] ISSN:0975-5764
[Cp] País de publicación:India
[La] Idioma:eng
[Mh] Términos MeSH primario: Infecciones por VIH/complicaciones
Hiperlipidemias/epidemiología
Hiperlipidemias/metabolismo
Lípidos/sangre
[Mh] Términos MeSH secundario: Femenino
Humanos
Masculino
[Pt] Tipo de publicación:COMMENT; LETTER
[Nm] Nombre de substancia:
0 (Lipids)
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140613
[St] Status:MEDLINE
[do] DOI:10.4103/1596-3519.134424


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[PMID]:24923368
[Au] Autor:Salaudeen AG; Musa OI; Ojotule A; Yusuf AS; Durowade KA; Omokanye LO
[Ad] Dirección:Department of Epidemiology and Community Health, University of Ilorin, Ilorin, Nigeria.
[Ti] Título:Condom use among people living with HIV/AIDS attending Abejukolo General Hospital in Kogi State, North Central Nigeria.
[So] Fuente:Ann Afr Med;13(3):99-103, 2014 Jul-Sep.
[Is] ISSN:0975-5764
[Cp] País de publicación:India
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: Condom programming is an integral component in a range of HIV/AIDS prevention strategies and with repeated sexual contact among HIV-discordant couples, 98-100% of those who used latex condoms correctly and consistently did not become infected. The objective of this study is to determine condom use among people living with HIV/AIDS (PLWHA). METHODS: This is a cross-sectional survey carried out among 231 PLWHA and receiving care and treatment at General Hospital Abejukolo in Kogi State, Nigeria. The research instrument was interviewer-administered questionnaire. The data obtained were analysed using EPI-INFO version 3.4.1 software and P-value of < 0.05 was significant for the study. RESULTS: About three-quarters (70.6%) of the respondents had ever used condom. Reasons given by respondents who did not use condom were: Desire for children (39.7%), and reduction of sexual pleasure (17.7%) and partner preference. More than half (56.0%) of the respondents with multiple partners did not use condom. About half 119 (51.5%) have used condom in the last sexual encounter. Gender, literacy level and disclosure of HIV status to partners significantly influence condom use during sexual intercourse. CONCLUSION: The poor uptake of condom among PLWHA underscores the need for government and other stakeholders in the management of HIV/AIDS to provide more enlightenment opportunities to address the gaps in condom use and disclosure of HIV status to partners.
[Mh] Términos MeSH primario: Condones/utilización
Infecciones por VIH/prevención & control
Conducta Sexual/estadística & datos numéricos
Parejas Sexuales
[Mh] Términos MeSH secundario: Adolescente
Adulto
Condones/estadística & datos numéricos
Estudios Transversales
Femenino
Conocimientos, Actitudes y Práctica en Salud
Encuestas Epidemiológicas
Hospitales Generales
Humanos
Masculino
Mediana Edad
Motivación
Nigeria
Cuestionarios
Conducta Sexual/etnología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140613
[St] Status:MEDLINE
[do] DOI:10.4103/1596-3519.134378


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[PMID]:24761799
[Au] Autor:Manyanga VP; Minzi O; Ngasala B
[Ti] Título:Prevalence of malaria and anaemia among HIV infected pregnant women receiving co-trimoxazole prophylaxis in Tanzania: a cross sectional study in Kinondoni Municipality.
[So] Fuente:BMC Pharmacol Toxicol;15:24, 2014.
[Is] ISSN:2050-6511
[Cp] País de publicación:England
[La] Idioma:eng
[Ab] Resumen:BACKGROUND: HIV-infected pregnant women are particularly more susceptible to the deleterious effects of malaria infection particularly anaemia. In order to prevent opportunistic infections and malaria, a policy of daily co-trimoxazole prophylaxis without the standard Suphadoxine-Pyrimethamine intermittent preventive treatment (SP-IPT) was introduced to all HIV infected pregnant women in the year 2011. However, there is limited information about the effectiveness of this policy. METHODS: This was a cross sectional study conducted among HIV-infected pregnant women receiving co-trimoxazole prophylaxis in eight public health facilities in Kinondoni Municipality from February to April 2013. Blood was tested for malaria infection and anaemia (haemoglobin <11 g/dl). Data were collected on the adherence to co-trimoxazole prophylaxis and other risk factors for malaria infection and anaemia. Pearson chi-square test, Fischer's exact test and multivariate logistic regression were used in the statistical analysis. RESULTS: This study enrolled 420 HIV infected pregnant women. The prevalence of malaria infection was 4.5%, while that of anaemia was 54%. The proportion of subjects with poor adherence to co-trimoxazole was 50.5%. As compared to HIV infected pregnant women with good adherence to co-trimoxazole prophylaxis, the poor adherents were more likely to have a malaria infection (Adjusted Odds Ratio, AOR = 6.81, 95% CI = 1.35-34.43, P = 0.02) or anaemia (AOR = 1.75, 95% CI = 1.03-2.98, P = 0.039). Other risk factors associated with anaemia were advanced WHO clinical stages, current malaria infection and history of episodes of malaria illness during the index pregnancy. CONCLUSION: The prevalence of malaria was low; however, a significant proportion of subjects had anaemia. Good adherence to co-trimoxazole prophylaxis was associated with reduction of both malaria infection and anaemia among HIV infected pregnant women.
[Mh] Términos MeSH primario: Anemia/epidemiología
Antiinfecciosos/uso terapéutico
Profilaxis Antibiótica
Infecciones por VIH/epidemiología
Malaria/epidemiología
Combinación Trimetoprim-Sulfametoxazol/uso terapéutico
[Mh] Términos MeSH secundario: Adulto
Anemia/diagnóstico
Anemia/quimioterapia
Anemia/inmunología
Recuento de Linfocito CD4
Estudios Transversales
Femenino
Infecciones por VIH/quimioterapia
Infecciones por VIH/inmunología
Hemoglobinas/análisis
Humanos
Malaria/diagnóstico
Malaria/quimioterapia
Malaria/inmunología
Embarazo
Prevalencia
Tanzanía/epidemiología
Adulto Joven
[Pt] Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nombre de substancia:
0 (Anti-Infective Agents); 0 (Hemoglobins); 8064-90-2 (Trimethoprim-Sulfamethoxazole Combination)
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM
[Da] Fecha de ingreso para procesamiento:140603
[St] Status:MEDLINE
[do] DOI:10.1186/2050-6511-15-24


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[PMID]:24725599
[Au] Autor:Bradley-Springer L
[Ti] Título:A death in the family.
[So] Fuente:J Assoc Nurses AIDS Care;25(3):189-90, 2014 May-Jun.
[Is] ISSN:1552-6917
[Cp] País de publicación:United States
[La] Idioma:eng
[Mh] Términos MeSH primario: Muerte
Pesar
Infecciones por VIH
Publicaciones Periódicas como Asunto
[Mh] Términos MeSH secundario: Historia del Siglo XX
Humanos
Enfermería
Publicaciones Periódicas como Asunto/historia
Edición
Sociedades de Enfermería/historia
[Pt] Tipo de publicación:BIOGRAPHY; EDITORIAL; HISTORICAL ARTICLE; PORTRAITS
[Ps] Nombre personal como asunto:Patsdaughter C
[Em] Mes de ingreso:1409
[Sb] Subgrupo de revista:IM; N; X
[Da] Fecha de ingreso para procesamiento:140414
[St] Status:MEDLINE



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