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Search on : Acanthoma [Words]
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SciELO Brazil full text

[PMID]: 29267474
[Au] Autor:Espinosa AED; Akay BN; González-Ramírez RA
[Ad] Address:Department of Dermatology, Hospital General de Zona 8 "Gilberto Flores Izquierdo" IMSS. - Mexico City, Mexico.
[Ti] Title:"String of pearls pattern": report of three cases of non clear-cell acanthoma.
[So] Source:An Bras Dermatol;92(5 Suppl 1):142-144, 2017.
[Is] ISSN:1806-4841
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:The coiled and dotted vessels in a serpiginous arrangement or "string of pearls" is considered a classical vascular pattern associated with clear cell acanthoma. We present three cases of epidermal tumors different from clear cell acanthoma that have the same "string of pearls" vascular pattern. Even though most authors keep considering the "string of pearls" vascular pattern an almost pathognomonic sign of clear-cell acanthoma, the cases presented here suggest that some other epidermal tumors can also show this pattern.
[Pt] Publication type:CASE REPORTS
[Em] Entry month:1712
[Cu] Class update date: 171224
[Lr] Last revision date:171224
[St] Status:In-Process

  2 / 430 MEDLINE  
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SciELO Brazil full text

[PMID]: 29267438
[Au] Autor:González-Guerra E; Rodriguez JR; Casado AF; Taboada AC; Toro JAC; Bran EL
[Ad] Address:Department of Dermatology, Hospital Clínico San Carlos - Madrid, Spain.
[Ti] Title:Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids.
[So] Source:An Bras Dermatol;92(5 Suppl 1):27-29, 2017.
[Is] ISSN:1806-4841
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Clear cell acanthoma is a rare, epidermal tumor not common in the area of the nipples; indeed, the literature describes only 8 cases, all showing unilateral presentation. We here report the first case of bilateral clear cell acanthoma with good response to topical corticosteroids. CASE REPORT: A sixteen-year old girl presented with 2 excrescent, fleshy, and exudative tumor masses in both nipples and areola mammae. A biopsy was conducted and confirmed clear cell acanthoma histopathologically. Treatment with strong corticosteroids resulted in rapid improvement and resolution. After one year of follow-up, the patient developed atopic dermatitis. DISCUSSION: We describe the first case of bilateral clear cell acanthoma localized in the nipple/areola that resolved with powerful corticosteroids, suggesting a reactive etiology of the lesion.
[Pt] Publication type:CASE REPORTS
[Em] Entry month:1712
[Cu] Class update date: 171224
[Lr] Last revision date:171224
[St] Status:In-Process

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[PMID]: 29090469
[Au] Autor:Lee TJ; Wu YH
[Ad] Address:Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
[Ti] Title:Multiple epidermolytic acanthomas mimicking condyloma: a retrospective study of 8 cases.
[So] Source:Int J Dermatol;, 2017 Oct 31.
[Is] ISSN:1365-4632
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Epidermolytic acanthoma (EA) is an uncommon benign cutaneous lesion. Multiple epidermolytic acanthomas (multiple EAs) are rarely reported. METHODS: We retrospectively identified patients diagnosed with multiple EAs between 2005 and 2017 from our dermatopathology database and analyzed their clinical, pathological, and immunohistochemical features. We also evaluated the association of multiple EAs with human papillomavirus (HPV) infection. RESULTS: In total, eight patients (average age 51 years; 3 : 1 male predominance) with multiple EAs were found. All patients had lesions on the genitocrural area. The two most common clinical diagnoses were condyloma (5/8) and soft fibroma (3/8), which were predominantly skin-colored (5/8) or whitish (2/8). The lesions were less than 1 cm in diameter, and most (6/8) appeared to have a smooth surface. No molecular evidence suggesting HPV infection was found. Immunohistochemical staining showed low mitotic activity. The lesions were removed in one of two patients via cryotherapy, and one patient was treated with electrocauterization. The other five patients were followed without treatment. CONCLUSION: The genital area was the most common location for multiple EAs, which was commonly misdiagnosed clinically as condyloma. Patients presenting with uniformly small-sized, skin-colored to whitish, smooth papular lesions in the genitalia should be carefully evaluated. The specific pathological features of epidermolytic hyperkeratosis are diagnostic, and the lesions can be observed without aggressive treatment after confirmed diagnosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171101
[Lr] Last revision date:171101
[St] Status:Publisher
[do] DOI:10.1111/ijd.13818

  4 / 430 MEDLINE  
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[PMID]: 29085717
[Au] Autor:Ribeiro F; Leocadia E; Macarenco RS; Lapins J; Huet P; Akay BN; Steiner D
[Ad] Address:Department of Dermatology, Mogi das Cruzes University, Mogi das Cruzes, Brazil.
[Ti] Title:Reticulated acanthoma with sebaceous differentiation mimicking melanoma.
[So] Source:Dermatol Pract Concept;7(3):35-37, 2017 Jul.
[Is] ISSN:2160-9381
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous tumor with peculiar histopathologic characteristics [1]. RASD had been described under various synonyms such as superficial epithelioma with sebaceous differentiation, sebocrine adenoma, poroma with sebaceous differentiation, and seborrheic keratosis with sebaceous differentiation [2]. Clinical differential diagnosis of RASD includes cutaneous superficial epithelial neoplasia such as Bowen's disease, superficial basal cell carcinoma (BCC) and intraepidermal eccrine poroma [1]. We report the first case of RASD mimicking both clinically and dermoscopically a melanoma.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.5826/dpc.0703a07

  5 / 430 MEDLINE  
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[PMID]: 28868008
[Au] Autor:Rojhirunsakool S; Jirasuthat S; Chanprapaph K
[Ad] Address:Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
[Ti] Title:Epidermolytic Acanthoma on Fingers, Mimicking Flat Warts.
[So] Source:Case Rep Dermatol;9(2):98-101, 2017 May-Aug.
[Is] ISSN:1662-6567
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:Epidermolytic acanthoma (EA) is a benign cutaneous condition. It is characterized by warty or flat-topped, keratotic papules that show epidermolytic hyperkeratosis in histology. EA has been described to occur in various locations, namely the trunk, face, and genitoscrotal area. However, it has not been previously reported to involve the palmar area. To the best of our knowledge, we present the first reported case of EA involving the palms and fingers.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1159/000478890

  6 / 430 MEDLINE  
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[PMID]: 28857272
[Au] Autor:Sokolowska-Wojdylo M; Olszewska B; Sobjanek M; Slawinska M; Sosinska-Mielcarek K; Biernat W; Nowicki R
[Ad] Address:Department of Dermatology, Venerology and Allergology, Medical University of Gdansk, Gdansk, Poland.
[Ti] Title:Acanthoma planoepitheliale hyperkeratoticum, lesions associated with BRAF inhibitor in metastatic melanoma.
[So] Source:J Eur Acad Dermatol Venereol;, 2017 Aug 30.
[Is] ISSN:1468-3083
[Cp] Country of publication:England
[La] Language:eng
[Pt] Publication type:LETTER
[Em] Entry month:1709
[Cu] Class update date: 170923
[Lr] Last revision date:170923
[St] Status:Publisher
[do] DOI:10.1111/jdv.14540

  7 / 430 MEDLINE  
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[PMID]: 28711100
[Au] Autor:Behera B; Gochhait D; Sridivya P; Chandana S; Thappa DM; Malathi M
[Ad] Address:Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
[Ti] Title:Dermoscopy of a solitary verrucous plaque on the back.
[So] Source:J Am Acad Dermatol;77(2):e37-e39, 2017 08.
[Is] ISSN:1097-6787
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:In-Process

  8 / 430 MEDLINE  
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Alves, Ana Paula Negreiros Nunes

[PMID]: 28658350
[Au] Autor:Dantas TS; Nascimento IVD; Verde MEQL; Alves APNN; Sousa FB; Mota MRL
[Ad] Address:Divisão de Patologia Oral, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brasil.
[Ti] Title:Multifocal oral melanoacanthoma associated with Addison's disease and hyperthyroidism: a case report.
[So] Source:Arch Endocrinol Metab;61(4):403-407, 2017 Jul-Aug.
[Is] ISSN:2359-4292
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Oral melanoacanthoma is a mucocutaneous, pigmented, rare, benign, and probably reactive lesion. This paper reports for the first time in the literature a case of multifocal oral melanoacanthoma in a patient diagnosed with Addison's disease and concomitant Graves' disease with hyperthyroidism. The patient presented with oral pigmented lesions, which were hypothesized to be mucosal pigmentation associated with Addison's disease. Due to their unusual clinical pattern, these oral lesions were biopsied and diagnosed as oral melanoacanthoma on histopathology and immunohistochemistry for HMB-45. At the moment of this report, the patient was being treated for her systemic conditions, but the lesions had not regressed. Reactive hyperpigmentation of the skin and mucous membranes may be found in Addison's disease and hyperthyroidism. This case reinforces the hypothesis of a reactive nature for oral melanoacanthoma and highlights the need for investigation of endocrine disorders in patients with multifocal oral melanoacanthoma.
[Mh] MeSH terms primary: Acanthoma/pathology
Mouth Neoplasms/pathology
Skin Neoplasms/pathology
[Mh] MeSH terms secundary: Acanthoma/complications
Acanthoma/diagnosis
Addison Disease/complications
Biopsy
Female
Graves Disease/complications
Humans
Hyperpigmentation/diagnosis
Hyperpigmentation/etiology
Middle Aged
Mouth Neoplasms/complications
Mouth Neoplasms/diagnosis
Skin Neoplasms/complications
Skin Neoplasms/diagnosis
[Pt] Publication type:CASE REPORTS
[Em] Entry month:1710
[Cu] Class update date: 171016
[Lr] Last revision date:171016
[Js] Journal subset:IM
[Da] Date of entry for processing:170629
[St] Status:MEDLINE

  9 / 430 MEDLINE  
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[PMID]: 28627087
[Au] Autor:Agustí J; Bella-Navarro R; García-García AB; Bueno E; González-Sarmiento R; Navarro L; Sanchez-Sendra B; Revert A; Jordá E; Monteagudo C
[Ad] Address:Department of Pathology, Hospital Clínico Universitario-INCLIVA, University of Valencia, Valencia, Spain.
[Ti] Title:Familial seborrhoeic keratosis associated with multiple "pure reticulated acanthomas" and infundibulocystic basal cell carcinomas.
[So] Source:Br J Dermatol;, 2017 Jun 18.
[Is] ISSN:1365-2133
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: A variety of genodermatoses with multiple cutaneous tumors with germline genetic alterations such as Gorlin syndrome with PTCH1 gene mutations have been described. Other cutaneous syndromes have been associated with somatic gene mutations, such as FGFR3 in familial seborrhoeic keratosis. OBJECTIVE: We describe the clinical, dermoscopic, and histopathological features of multiple cutaneous lesions, mostly infundibulocystic basal cell carcinomas and pure reticulated acanthomas, present in a family affected by familial seborrhoeic keratosis. In addition, we tested for possible germline alterations in the FGFR3 and PTCH1 genes. METHODS: Ten members of one family were clinically examined. Ninety-two skin biopsy specimens were evaluated. Blood samples from six subjects were analyzed for FGFR3 and PTCH1 germline alterations. We review the literature concerning genetic FGFR3 alterations in seborrhoeic keratosis. RESULTS: Subjects of all generations affected by familial seborrhoeic keratosis also presented other skin tumors which corresponded histologically to reticulated acanthomas without apocrine or sebaceous differentiation as well as infundibulocystic basal cell carcinomas. In addition, two novel germline variants, p.Pro449Ser (c.1345C>T) in FGFR3 gene and p.Pro725Ser (c.2173C>T) in exon 14 of PTCH1 gene were identified in five subjects. CONCLUSION: We characterize for the first time the clinical, dermoscopic and histopathological features of multiple reticulated acanthomas without apocrine or sebaceous differentiation, for which we propose the term "pure reticulated acanthoma", and infundibulocystic basal cell carcinomas, associated with familial seborrhoeic keratosis. We identified FGFR3 and PTCH1 germline polymorphisms whose influence in the development of reticulated acanthomas is unknown. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 170619
[Lr] Last revision date:170619
[St] Status:Publisher
[do] DOI:10.1111/bjd.15736

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[PMID]: 28609346
[Au] Autor:Jo-Velasco M; Corrales-Rodríguez A; Francés-Rodríguez L; Alegría-Landa V; Eraña-Tomás I; Rütten A; Requena L
[Ad] Address:*Departments of Pathology and Dermatology, Fundación Jiménez Diaz, Universidad Autónoma, Madrid, Spain; †Department of Pathology, Hospital Universitario de Guadalajara, Guadalajara, Spain; and ‡Laboratory of Dermatopathology, Friedrichshafen, Germany.
[Ti] Title:Plaque-Like Pilar Sheath Acanthoma: Histopathologic and Immunohistochemical Study of 3 Unusual Cases.
[So] Source:Am J Dermatopathol;, 2017 Jun 06.
[Is] ISSN:1533-0311
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Pilar sheath acanthoma is an uncommon, benign follicular neoplasm that frequently presents as a solitary lesion. This neoplasm usually appears on the skin around the upper lip of elderly patients. Histopathologically, the neoplasm usually shows a cystic configuration with epithelial lobules resembling to those of the outer root sheath of the hair follicle at the level of the isthmus emanating radially from the cyst wall. We present 3 peculiar cases of a pilar sheath acanthoma showing a plaque-like architecture because the lesions exhibited a horizontal configuration. To our knowledge, there are no previously reported examples of plaque-like pilar sheath acanthoma.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 170613
[Lr] Last revision date:170613
[St] Status:Publisher
[do] DOI:10.1097/DAD.0000000000000936


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