Database : MEDLINE
Search on : Adenolymphoma [Words]
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[PMID]: 29346263
[Au] Autor:Huang K; Gao N; Wang X; Bian D; Liu Y; Zhai Q
[Ad] Address:Ultrasonic Diagnosis Department, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China.
[Ti] Title:Clinical Application of Real-Time Shear Wave Elastography in Identifying the Histological Components of Parotid Adenolymphoma.
[So] Source:Ultrasound Q;, 2018 Jan 17.
[Is] ISSN:1536-0253
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: This study aimed to investigate the relationship between the elastic modulus and the histological components of parotid adenolymphoma by using real-time shear wave elastography. METHODS: A total of 157 patients, histologically confirmed as having parotid adenolymphoma, were enrolled in the study. The maximum and the mean elastic modulus of the parotid mass were measured by using preoperative shear wave elastography. Parotid adenolymphoma was histopathologically subdivided into different types based on the relative proportion of stromal to cellular components. RESULTS: The maximal elasticity of parotid adenolymphoma ranged from 20.67 to 160.90 kPa, and the mean elasticity was 83.18 ± 39.15 kPa. The maximal elasticity of the 3 types of parotid adenolymphoma was 34.21 to 155.20, 20.67 to 104.20, and 45.89 to 160.90 kPa, respectively. The mean elasticity of the 3 types of parotid adenolymphoma was 89.16 ± 40.62, 63.24 ± 28.07, and 111.10 ± 37.85 kPa, respectively. The difference in the maximal elasticity among 3 groups was significant (P < 0.01). There was no significant difference in maximal elasticity of type II and type III as compared with type I adenolymphoma (P > 0.05). The maximal elasticity of type III adenolymphoma was significantly higher than that of type II (P < 0.05, t = 3.12). CONCLUSION: Shear wave elastography depicts parotid adenolymphoma with a variable appearance because of the relative proportions of stromal to cellular contents in the mass.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180118
[Lr] Last revision date:180118
[St] Status:Publisher
[do] DOI:10.1097/RUQ.0000000000000321

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[PMID]: 29224806
[Au] Autor:Chen AA; Gheit T; Stellin M; Lupato V; Spinato G; Fuson R; Menegaldo A; Mckay-Chopin S; Dal Cin E; Tirelli G; Da Mosto MC; Tommasino M; Boscolo-Rizzo P
[Ad] Address:Section of Infections, International Agency for Research on Cancer, Lyon, France.
[Ti] Title:Oncogenic DNA viruses found in salivary gland tumors.
[So] Source:Oral Oncol;75:106-110, 2017 Dec.
[Is] ISSN:1879-0593
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Previous investigations studying the association of DNA viruses with salivary gland tumors (SGTs) have led to conflicting results. The aim of this study was to determine the prevalence of different DNA viruses by using a highly sensitive assay in a multi-center series of over 100 fresh frozen salivary gland samples. METHODS: DNA was isolated from 84 SGTs (80 parotid tumors and 4 submandibular gland tumors) and 28 normal salivary tissue samples from 85 patients in Northeast Italy. Using a highly sensitive type-specific multiplex genotyping assay, we analyzed the samples for the presence of DNA from 62 different viruses including 47 papillomaviruses, 10 polyomaviruses, and 5 herpesviruses. RESULTS: We observed a high prevalence of beta human papillomavirus DNA in malignant tumors. In contrast, polyomavirus DNA was present in benign, malignant, and non-tumor control samples. Most striking was the significant distribution of herpesvirus DNA in the SGT samples, in particular the high prevalence of Epstein-Barr type 1 and type 2 DNA in Warthin's tumor samples. CONCLUSION: Our data provides evidence for the presence of DNA viruses in SGTs. Mechanistic studies are needed to further attribute tumor formation to these viruses.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171211
[Lr] Last revision date:171211
[St] Status:In-Process

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[PMID]: 28628159
[Ti] Title:[Diagnosis accuracy of fine-needle aspiration cytology for vascular anomalies].
[So] Source:Beijing Da Xue Xue Bao Yi Xue Ban;49(3):527-530, 2017 Jun 18.
[Is] ISSN:1671-167X
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To evaluate the feasibility of fine-needle aspiration cytology (FNAC) in diagnosing vascular abnormality in oral and maxillofacial region. METHODS: The method of retrospective study was used. The data from the patients who underwent FNAC from 2011 to 2014 in Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology were collected. All the included patients were divided into surgery group and non-surgery group. The patients in surgery group underwent lesion resection and the postoperative pathological results were gained. The patients in non-surgery group underwent periodical sclerotherapy. The accuracy of FNAC was identified by histopathologic diagnosis in surgery group and the effect of sclerotherapy in non-surgery group. RESULTS: In this study, 93 patients were involved, including 51 males and 42 females. The median age was 2.5 years. Among them, 67 cases were judged as vascular abnormality by FNAC, and 63 cases were in consistent with final diagnosis and 4 cases were not. Among the other 26 cases which were diagnosed as other diseases by FNAC, 5 cases were accorded with final diagnosis. Therefore, the sensitivity of FNAC on diagnosis of vascular abnormity was 93% and its specificity was 84%. Among them, there were 29 cases in the surgery group and 64 cases in the non-surgery group. FNAC results were in consistent with the postoperative pathological results in 20 cases in surgery group (69%), and not consistent with pathological results in 9 cases . The pathological diagnoses included vascular malformations (3 cases), neurofibromas (2 cases), hamartoma (1 case), sebaceous cyst (1 case), adenolymphoma (1 case), and descriptive diagnosis (1 case). In non-surgery group, FNAC results were in consistent with the clinical effect of sclerotherapy in 61 cases (95%). There were 3 misdiagnosed cases. The coincident rate between the result of FNAC and that of pathological or clinical diagnosis was 86%. CONCLUSION: FNAC is a feasible and minimal invasive method to diagnose vascular abnormality in oral and maxillofacial region.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[St] Status:In-Process

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[PMID]: 28541244
[Au] Autor:Chloupek A; Zarzycki K; Dabrowski J; Domanski W
[Ad] Address:Kliniczny Oddzial Chirurgii Czaszkowo-Szczekowo-Twarzowej Kliniki Otolaryngologii i Onkologii Laryngologicznej Wojskowego Instytutu Medycznego w Warszawie; Kierownik kliniki: prof. dr hab. med. Dariusz Jurkiewicz.
[Ti] Title:Parotid gland tumors. Results of retrospective analysis of 149 patients treated at the Clinical Department of Cranio-Maxillofacial Surgery, Clinic of Otolaryngology and Oncologic Laryngology of Military Institute of Medicine in Warsaw in years 2006-2016.
[So] Source:Otolaryngol Pol;71(3):37-42, 2017 Jun 30.
[Is] ISSN:2300-8423
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Wstep: Nowotwory majace swoja etiologie w gruczolach slinowych wystepuja rzadko i stanowia ok. 3-10% wszystkich guzów w obrebie glowy i szyi. Material i metody: W latach 2006-2016 w Klinicznym Oddziale Chirurgii Czaszkowo-Szczekowo-Twarzowej Wojskowego Instytutu Medycznego w Warszawie z powodu nowotworów slinianek przyusznych hospitalizowano i leczono 149 pacjentów. Podstawa do analizy byly historie chorób pacjentów, wyniki badan histopatologicznych oraz protokoly zabiegów operacyjnych. Wyniki: W 126 przypadkach guzy byly lagodne, natomiast w 26 guzy zlosliwe. Analizujac wyniki mozna stwierdzic, ze nowotwory - zarówno lagodne, jak i zlosliwe - czesciej wystepowaly u mezczyzn. Sredni wiek calej grupy badanych wynosil 58,3 lat, dla zmian zlosliwych - 65,5 lat, a dla zmian lagodnych byl nieznacznie nizszy i wynosil 56,9 lat. Wsród pacjentów objetych analiza szczyt zachorowalnosci przypadal na przedzial wiekowy 60-69 lat. Ponadto zwraca uwage, iz przedzial ten byl taki sam dla ogólnej liczby guzów, jak i nowotworów lagodnych, natomiast dla nowotworów zlosliwych byl nieznacznie wyzszy i wynosil 70-79 lat. Z analizy zebranego materialu wynika, ze guzy lagodne wystepowaly znamiennie czesciej, stanowiac 84,56% wszystkich guzów. Najczestszymi rozpoznaniami wsród nowotworów lagodnych byly gruczolak wielopostaciowy (adenoma pleomorphicum) oraz gruczolak limfatyczny (adenolymphoma), które stanowily lacznie 93,66%. Rezultaty badan wskazuja, ze wsród nowotworów zlosliwych dominowaly: gruczolakorak polimorficzny o niskiej zlosliwosci (polymorphous low-grade adenocarcinoma) wystepujacy w 26,07% przypadków, gruczolakorak inaczej nieokreslony (adenocarcinoma NOS) oraz rak zrazikowokomórkowy (acinic cell carcinoma). Kazdy z nich stanowil po 13,04% rozpoznan. Jak wynika z przeprowadzonej analizy najczestsza metoda leczenia bylo leczenie chirurgiczne jako metoda stosowana samodzielnie. Wnioski: Uzyskane z retrospektywnej analizy dane koreluja z pismiennictwem krajowym i swiatowym.
[Mh] MeSH terms primary: Parotid Neoplasms/diagnosis
Parotid Neoplasms/therapy
[Mh] MeSH terms secundary: Adenolymphoma/diagnosis
Adenolymphoma/therapy
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell/diagnosis
Carcinoma, Squamous Cell/therapy
Female
Humans
Male
Middle Aged
Neoplasm Staging
Otolaryngology
Otorhinolaryngologic Surgical Procedures/statistics & numerical data
Parotid Neoplasms/epidemiology
Poland
Retrospective Studies
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171004
[Lr] Last revision date:171004
[Js] Journal subset:IM
[Da] Date of entry for processing:170526
[St] Status:MEDLINE
[do] DOI:10.5604/01.3001.0010.0131

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[PMID]: 28411376
[Au] Autor:Rooper LM; Onenerk M; Siddiqui MT; Faquin WC; Bishop JA; Ali SZ
[Ad] Address:Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland.
[Ti] Title:Nodular oncocytic hyperplasia: Can cytomorphology allow for the preoperative diagnosis of a nonneoplastic salivary disease?
[So] Source:Cancer;125(8):627-634, 2017 Aug.
[Is] ISSN:1097-0142
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Nodular oncocytic hyperplasia (oncocytosis) of the salivary glands is a benign process that does not inherently require surgical excision. However, cytologic findings in fine-needle aspiration (FNA) of oncocytosis cases have not been well characterized previously, limiting preoperative identification. METHODS: All available cases of oncocytosis with corresponding FNA specimens were identified from the pathology archives of 3 academic institutions. Clinical, cytologic, and histologic findings were tabulated for all cases. RESULTS: Twelve cases of oncocytosis were identified from 11 patients, including 11 parotid FNA specimens and 1 submandibular FNA specimen. On the original diagnoses, 6 specimens were classified as benign, 4 as atypical, and 2 as nondiagnostic. Oncocytosis was listed in the differential diagnosis in only 1 case. Among diagnostic aspirates, 8 demonstrated low cellularity and 2 demonstrated moderate cellularity. All 10 cases demonstrated oncocytic cells in small to medium groups, with single cells in just 1 case. Spindled and squamous morphology were each noted in 3 cases. Four cases demonstrated cystic change and 1 showed background mucin without goblet cells. No necrosis or mitoses were observed. CONCLUSIONS: Although oncocytosis demonstrates some overlap with Warthin tumor and oncocytoma, it lacks the diagnostic findings specific to oncocytic salivary gland malignancies such as salivary duct carcinoma, acinic cell carcinoma, mammary analog secretory carcinoma, and mucoepidermoid carcinoma. Despite current limitations in the understanding of oncocytic salivary gland lesions, the presence of a paucicellular specimen comprised of small groups of oncocytic cells should raise the possibility of oncocytosis in the differential diagnosis and can favor it in elderly patients with multiple salivary nodules. Cancer Cytopathol 2017;125:627-34. © 2017 American Cancer Society.
[Mh] MeSH terms primary: Oxyphil Cells/pathology
Parotid Diseases/pathology
Submandibular Gland Diseases/pathology
[Mh] MeSH terms secundary: Adenolymphoma/diagnosis
Adenolymphoma/pathology
Adenoma, Oxyphilic/diagnosis
Adenoma, Oxyphilic/pathology
Aged
Aged, 80 and over
Biopsy, Fine-Needle
Carcinoma/diagnosis
Carcinoma/pathology
Carcinoma, Acinar Cell/diagnosis
Carcinoma, Acinar Cell/pathology
Carcinoma, Mucoepidermoid/diagnosis
Carcinoma, Mucoepidermoid/pathology
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Parotid Diseases/diagnosis
Salivary Gland Diseases/diagnosis
Salivary Gland Diseases/pathology
Salivary Gland Neoplasms/diagnosis
Salivary Gland Neoplasms/pathology
Submandibular Gland Diseases/diagnosis
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170918
[Lr] Last revision date:170918
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170416
[St] Status:MEDLINE
[do] DOI:10.1002/cncy.21865

  6 / 1440 MEDLINE  
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[PMID]: 28226379
[Au] Autor:Keesecker S; Saab J; Magro CM; Dokania V; Sclafani AP
[Ad] Address:Department of Otolaryngology-Head and Neck Surgery, Joan and Sanford I Weill Medical College of Cornell University, New York, New York.
[Ti] Title:Cutaneous Lymphadenoma: A Trichoblastoma with Regressive Inflammatory Changes.
[So] Source:Facial Plast Surg;33(1):109-111, 2017 Feb.
[Is] ISSN:1098-8793
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The authors address the entity of cutaneous lymphadenoma. Although considered benign, cutaneous lymphadenoma can be easily misdiagnosed as basal cell carcinoma because of its close clinical and histological resemblance. This entity is rare and controversial both in terms of its histogenesis and the various diagnostic terms assigned to it throughout the literature. While rare, cutaneous lymphadenoma should be considered in the differential of any facial nodule or papule in addition to the more common basal cell carcinoma, nevi, cysts, and appendiceal tumors.
[Mh] MeSH terms primary: Adenolymphoma/pathology
CD3 Complex/analysis
Skin Neoplasms/pathology
T-Lymphocytes/chemistry
[Mh] MeSH terms secundary: Adenolymphoma/complications
Humans
Inflammation/pathology
Skin Neoplasms/complications
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (CD3 Complex)
[Em] Entry month:1710
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:D
[Da] Date of entry for processing:170223
[St] Status:MEDLINE
[do] DOI:10.1055/s-0036-1597951

  7 / 1440 MEDLINE  
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[PMID]: 28095049
[Au] Autor:Rafii DC; Greif EF; Finestone H; Karam J
[Ad] Address:From the 1Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York.
[Ti] Title:Visual Vignette.
[So] Source:Endocr Pract;23(7):891, 2017 Jul.
[Is] ISSN:1530-891X
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Adenolymphoma/diagnostic imaging
Carcinoma/diagnostic imaging
Parotid Neoplasms/diagnostic imaging
Thyroid Neoplasms/diagnostic imaging
[Mh] MeSH terms secundary: Carcinoma/secondary
Carcinoma, Papillary
Diagnosis, Differential
Humans
Iodine Radioisotopes
Magnetic Resonance Imaging
Male
Middle Aged
Radionuclide Imaging
Thyroid Neoplasms/secondary
Ultrasonography
Whole Body Imaging
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Iodine Radioisotopes)
[Em] Entry month:1709
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:170118
[St] Status:MEDLINE
[do] DOI:10.4158/EP161687.VV

  8 / 1440 MEDLINE  
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[PMID]: 28074380
[Au] Autor:Kato H; Fujimoto K; Matsuo M; Mizuta K; Aoki M
[Ad] Address:Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan. hkato@gifu-u.ac.jp.
[Ti] Title:Usefulness of diffusion-weighted MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland.
[So] Source:Jpn J Radiol;35(2):78-85, 2017 Feb.
[Is] ISSN:1867-108X
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:PURPOSE: To assess the efficacy of diffusion-weighted (DW) MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. METHODS: Forty-five histopathologically confirmed parotid gland tumors (41 Warthin's tumors and 4 oncocytomas) were examined by MR imaging including DW imaging. F-fluorodeoxyglucose PET/CT was also performed in 9 Warthin's tumors and 3 oncocytomas. We retrospectively reviewed the images and compared the MR signal intensities, apparent diffusion coefficients (ADCs), and maximum standardized uptake values (SUVmax) of the solid components between the two pathologies. RESULTS: The signal intensity ratios (SIRs) on both T2-weighted images (0.92 ± 0.18 vs 0.65 ± 0.13, p < 0.01) and DW images (1.24 ± 0.42 vs 0.43 ± 0.16, p < 0.001) were higher in Warthin's tumors than in oncocytomas. ADCs (0.79 ± 0.11 vs 1.06 ± 0.06 × 10 mm /s, p < 0.001) were lower in Warthin's tumors than in oncocytomas. No significant differences in the SIRs on T1-weighted images (1.09 ± 0.12 vs. 0.99 ± 0.07, p = 0.051) and SUVmax (8.22 ± 3.86 vs. 8.11 ± 1.33, p = 0.864) were found between Warthin's tumor and oncocytoma. CONCLUSION: DW imaging with ADC measurements is useful for the differentiation of Warthin's tumor from oncocytoma of the parotid gland.
[Mh] MeSH terms primary: Adenolymphoma/diagnostic imaging
Adenoma, Oxyphilic/diagnostic imaging
Diffusion Magnetic Resonance Imaging/methods
Parotid Neoplasms/diagnostic imaging
[Mh] MeSH terms secundary: Aged
Aged, 80 and over
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Parotid Gland/diagnostic imaging
Reproducibility of Results
Retrospective Studies
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 171104
[Lr] Last revision date:171104
[Js] Journal subset:IM
[Da] Date of entry for processing:170112
[St] Status:MEDLINE
[do] DOI:10.1007/s11604-016-0608-5

  9 / 1440 MEDLINE  
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[PMID]: 28013343
[Au] Autor:Sagiv D; Witt RL; Glikson E; Mansour J; Shalmon B; Yakirevitch A; Wolf M; Alon EE; Slonimsky G; Talmi YP
[Ad] Address:Department of Otolaryngology Head and Neck Surgery, The Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel. Doron.Sagiv@sheba.health.gov.il.
[Ti] Title:Warthin tumor within the superficial lobe of the parotid gland: a suggested criterion for diagnosis.
[So] Source:Eur Arch Otorhinolaryngol;274(4):1993-1996, 2017 Apr.
[Is] ISSN:1434-4726
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:The location of Warthin tumor (WT) in the parotid gland impacts the surgical approach and may be indicative of the elusive origin of this intriguing entity. Location in the deep versus superficial lobe of the gland is not directly addressed when defining WT characteristics. Our observation, of rare occurrence of deep lobe WT, if at all, led to the current investigation. The study design is cohort study. This is a retrospective chart review of all patients undergoing parotidectomy for WT in two tertiary academic referral centers: the Sheba Medical Center (SMC), Israel, and the Christiana Care (CC), Newark, Delaware, USA. 122 consecutive adult patients underwent parotidectomy for WT (72 from SMC and 50 from CC). Seventy percent were males, with a mean age of 60.6 years. Bilateral WT or multi-centric WT were found in 9.8 and 17.2% of the cases, respectively. In one case, the tumor was described as originating in the deep lobe. In all other cases, the tumor originated and was limited to the superficial lobe. 99.2% of WT originated in the superficial lobe, corresponding with the few reports directly addressing its location in the gland. The reason for the tumor to be limited almost uniformly to the superficial lobe is unknown, and could be related to the etiopathogenesis of this elusive entity. We suggest adding tumor location within the superficial lobe to the common characteristics of WT (male, smoking, and lower pole) that serve as "common criterion" while evaluating a parotid lesion.
[Mh] MeSH terms primary: Adenolymphoma
Parotid Gland
Parotid Neoplasms
[Mh] MeSH terms secundary: Adenolymphoma/pathology
Adenolymphoma/surgery
Adult
Aged
Female
Humans
Israel
Male
Middle Aged
Outcome Assessment (Health Care)
Parotid Gland/pathology
Parotid Gland/surgery
Parotid Neoplasms/pathology
Parotid Neoplasms/surgery
Retrospective Studies
Tumor Burden
United States
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1705
[Cu] Class update date: 170928
[Lr] Last revision date:170928
[Js] Journal subset:IM
[Da] Date of entry for processing:161226
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-016-4436-0

  10 / 1440 MEDLINE  
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[PMID]: 27880945
[Au] Autor:Lundberg M; Munsterhjelm B; Mäkitie A; Leivo I
[Ad] Address:Department of Otorhinolaryngology - Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
[Ti] Title:Immunohistochemical Staining of Histological Fragments Derived from Salivary Gland Tumour Fine-Needle Biopsy Aspirates.
[So] Source:Acta Cytol;61(1):17-20, 2017.
[Is] ISSN:1938-2650
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:OBJECTIVES: The aim of this study was to describe a method for analysing histological fragments derived from fine- needle aspirate biopsy (FNAB) of salivary gland tumours (SGTs), and to evaluate the use of immunohistochemistry (IHC) on them. STUDY DESIGN: We reviewed all 509 FNAB pathology reports taken from SGTs at Helsinki University Hospital, Finland, between 1999 and 2009. In 51% of the cases (n = 209) "histo-fragments" had been obtained and 31 had been further analysed by IHC. Of these, 25 (81%) were available for review. We evaluated the benefit of IHC by relating its added value to the preoperative cytological diagnosis and its accuracy compared with the postoperative histological diagnosis. RESULTS: Most of the samples analysed by IHC were assigned a malignant diagnosis, with 12 different types of malignancy represented. IHC was advantageous in 76% of the cases. In the 108 studies using IHC in this series, antibodies to 36 different antigens were used. CONCLUSION: Analysis of histo-fragments in FNABs using IHC can be valuable in specific differential diagnostics and raises diagnostic accuracy in SGTs.
[Mh] MeSH terms primary: Adenolymphoma/diagnosis
Adenoma, Pleomorphic/diagnosis
Biomarkers, Tumor/genetics
Neoplasms/diagnosis
Salivary Gland Neoplasms/diagnosis
[Mh] MeSH terms secundary: Adenolymphoma/genetics
Adenolymphoma/metabolism
Adenolymphoma/pathology
Adenoma, Pleomorphic/genetics
Adenoma, Pleomorphic/metabolism
Adenoma, Pleomorphic/pathology
Biomarkers, Tumor/metabolism
Biopsy, Fine-Needle
DNA-Binding Proteins/genetics
DNA-Binding Proteins/metabolism
Diagnosis, Differential
Gene Expression
Humans
Immunohistochemistry
MART-1 Antigen/genetics
MART-1 Antigen/metabolism
Neoplasms/genetics
Neoplasms/metabolism
Neoplasms/pathology
Retrospective Studies
Salivary Gland Neoplasms/genetics
Salivary Gland Neoplasms/metabolism
Salivary Gland Neoplasms/pathology
Salivary Glands/metabolism
Salivary Glands/pathology
Sensitivity and Specificity
Transcription Factors
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Biomarkers, Tumor); 0 (DNA-Binding Proteins); 0 (MART-1 Antigen); 0 (TTF1 protein, human); 0 (Transcription Factors)
[Em] Entry month:1702
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:161124
[St] Status:MEDLINE
[do] DOI:10.1159/000452155


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