Database : MEDLINE
Search on : Angiomatosis [Words]
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[PMID]: 29515720
[Au] Autor:El Bakkaly A; Ettayebi F; Oubeja H; Erraji M; Zerhouni H
[Ad] Address:Service des Urgences Chirurgicales Pédiatriques, CHU Ibn Sina, Faculté de Médecine Mohammed V, Rabat, Maroc.
[Ti] Title:Syndrome de Bean chez l'enfant: à propos de deux cas. [Bean's syndrome in children: about two cases].
[So] Source:Pan Afr Med J;28:102, 2017.
[Is] ISSN:1937-8688
[Cp] Country of publication:Uganda
[La] Language:fre
[Ab] Abstract:Diffuse angiomatosis or Bean's syndrome is a rare disease characterized by venous malformations mainly involving the skin and the digestive tract which can result in hemorrhage of variable severity. This study reports the case of two children aged 5 and 9 and a half years respectively with diffuse angiomatosis who had been treated in the Department of Emergency Paediatric Surgery over the years. The diagnosis was based on rectal bleeding and/or melenas causing severe anemia requiring regular transfusions in both patients as well as skin angiomas occurrence at the level of the limbs. Radiological evaluation showed the presence of multiple lesions at the level of the jejunum and ileum consistent with small intestinal angiomatosis in the child aged 9 and a half years. It didn't show abdominal lesions in the child aged 5 years. The two patients were admitted to the operating block. Angiomas were surgically individualized. Some of them were actively bleeding. Enterotomy was performed. Postoperative sequelae was marked by the stop of the bleedings. This study aims to update the current understanding of this rare pathology as well as the benefit of surgical treatment in controlling the complications caused by this pathology and in reducing the frequency of transfusions.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Process
[do] DOI:10.11604/pamj.2017.28.102.11109

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[PMID]: 29342032
[Au] Autor:Vahdani K; Kim YD; Suh YL; Kim JH
[Ad] Address:Bristol Eye Hospital, United Kingdom.
[Ti] Title:Angiomatosis of the Orbit: Clinical, Imaging, and Histologic Findings.
[So] Source:Ophthal Plast Reconstr Surg;34(2):e59-e61, 2018 Mar/Apr.
[Is] ISSN:1537-2677
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Angiomatosis is a complex vascular malformation that denotes a clinically extensive hemangioma, which either involves multiple tissue planes or extensively infiltrates 1 type of tissue. It is a rare condition characterized by diffuse proliferation of blood vessels admixed with fat and fibrotic tissue. Typically, this process involves the limbs in multiple tissue planes, including dermis, subcutis, muscle, and bone. In this report, the authors present the first case of angiomatosis infiltrating the orbit, controlled effectively with a combination of systemic steroids, radiation, and beta-blocker therapy. The characteristic imaging and histologic features and management options are discussed.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review
[do] DOI:10.1097/IOP.0000000000001035

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[PMID]: 29427537
[Au] Autor:Guido M; Sarcognato S; Russo FP; Cardin R; Piciocchi M; Colloredo G; Farinati F
[Ad] Address:Surgical Pathology & Cytopathology Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.
[Ti] Title:Focus on histological abnormalities of intrahepatic vasculature in chronic viral hepatitis.
[So] Source:Liver Int;, 2018 Feb 10.
[Is] ISSN:1478-3231
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND & AIMS: The histological intrahepatic microvasculature lesions have not been deeply investigated outside the setting of portal hypertension. The aim of this study was to analyse the type and the prevalence of microvasculature abnormalities and their correlation with inflammatory activity, fibrosis stage and tissue markers of fibrogenesis, angiogenesis and oxidative DNA damage in liver biopsies obtained from patients with chronic viral hepatitis. METHODS: Seventy-four liver biopsies from untreated patients affected by hepatitis B (22 cases) and C (52 cases) were included. The presence of microvascular changes was correlated with (i) the severity of the activity and fibrosis; (ii) immunohistochemical markers of angiogenesis (CD34) and hepatic stellate cells activation (alpha-smooth muscle actin); (iii) a tissue marker of oxidative damage (8-OHdG adducts). RESULTS: Sixty-five out of 74 biopsies (87.8%) showed vascular lesions. Portal angiomatosis was the most prevalent (62.2%) and it was associated with, on 1 side, the fibrosis stage at both univariate (P < .0001) and multivariate analysis (P = .01, OR = 9.4 [1.6-54]) and, on the other, with angiogenesis (P = .05) and hepatic stellate cells activation (P = .002). Interestingly, 36/46 cases with portal angiomatosis were at early/intermediate fibrosis stage. The hepatic stellate cells activation was also associated with the presence of aberrant periportal vessels (P = .01). CONCLUSIONS: The histological alterations of intrahepatic microvasculature, usually seen in cirrhosis and portal hypertension, occur in chronic viral hepatitis even at early/intermediate fibrosis stages. Their correlation with angiogenesis and fibrogenesis supports a possible involvement in disease progression.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher
[do] DOI:10.1111/liv.13718

  4 / 7284 MEDLINE  
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[PMID]: 28744985
[Au] Autor:Hui Y; Elco CP; Heinl NF; Lourenco AP; Wiggins DL; Wang Y
[Ad] Address:Department of Pathology, Alpert Medical School of Brown University, Providence, RI, USA.
[Ti] Title:Diffuse dermal angiomatosis mimicking inflammatory breast carcinoma.
[So] Source:Breast J;24(2):196-198, 2018 Mar.
[Is] ISSN:1524-4741
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Diffuse dermal angiomatosis (DDA) is a rare pathologically distinct subtype of reactive angioendotheliomatosis. In the literature, few biopsy-proven cases involving breast skin have been reported. We present a case of a 49-year-old female who presented with an indurated, erythematous, weeping, puckered and tender lesion with focal ulceration. Mammography demonstrated diffuse cutaneous and trabecular thickening concerning for inflammatory breast carcinoma. A punch biopsy demonstrated findings consistent with DDA. To our knowledge, this is the first reported case of DDA mimicking inflammatory carcinoma of the breast by clinical and radiologic examination.
[Pt] Publication type:CASE REPORTS
[Em] Entry month:1707
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Data-Review
[do] DOI:10.1111/tbj.12866

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[PMID]: 29488546
[Au] Autor:Núñez MA; Contreras K; Depix MS; Geoffroy E; Villagra N; Mellado S; Salinas AM
[Ad] Address:Escuela de Tecnología Médica, Universidad Santo Tomás, Santiago, Chile.
[Ti] Title:Prevalencia de Bartonella henselae en donantes de sangre y riesgo de transmisión sanguínea en Chile. [Prevalence of Bartonella henselae in blood donors and risk of blood transmission in Chile].
[So] Source:Rev Chilena Infectol;34(6):539-543, 2017 Dec.
[Is] ISSN:0717-6341
[Cp] Country of publication:Chile
[La] Language:spa
[Ab] Abstract:BACKGROUND: Bartonella henselae is the causal agent of cat scratch disease in immunocompetent persons and bacterial angiomatosis in immunocompromised patients. In Chile, the prevalence of antibodies against B. henselae in healthy children and adolescents is 13.3%, in persons with occupational risk 60.5%, and in cats 85.6%. There are no published data regarding the seroprevalence in blood donors in our country, so determining if B. henselae is present in the blood of donors at the time of donation is very important, since this microorganism can survive up to 35 days in the red blood cells stored in a blood bank at 4 °C. OBJECTIVE: To determine the prevalence of B. henselae in blood donors. METHODOLOGY: 140 donor blood samples were analyzed to detect the presence of B. henselae, using the polymerase chain reaction technique. RESULTS: 13.6% of the blood donors with positive polymerase chain reaction for B. henselae were obtained. The sequence of the amplified fragments showed an identity of over 98% with respect to B. henselae reference sequences. CONCLUSION: The risk of blood transmission is due to a country with high B. henselae infection.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180228
[Lr] Last revision date:180228
[St] Status:In-Data-Review

  6 / 7284 MEDLINE  
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[PMID]: 28466447
[Au] Autor:Gianotti G; Pinto D; Calogero P
[Ad] Address:Unità Operativa Geriatria, Dipartimento Medico della Continuità assistenziale e delle Disabilità, Azienda Ospedaliero-Universitaria Sant'Orsola-Malpighi, Bologna, Italy. giordanog87@gmail.com.
[Ti] Title:A case of suspected diffuse dermal angiomatosis associated with severe atherosclerosis.
[So] Source:Aging Clin Exp Res;30(2):213-215, 2018 Feb.
[Is] ISSN:1720-8319
[Cp] Country of publication:Germany
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1705
[Cu] Class update date: 180216
[Lr] Last revision date:180216
[St] Status:In-Data-Review
[do] DOI:10.1007/s40520-017-0764-1

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[PMID]: 29423877
[Au] Autor:Uusimaa J; Kaarteenaho R; Paakkola T; Tuominen H; Karjalainen MK; Nadaf J; Varilo T; Uusi-Mäkelä M; Suo-Palosaari M; Pietilä I; Hiltunen AE; Ruddock L; Alanen H; Biterova E; Miinalainen I; Salminen A; Soininen R; Manninen A; Sormunen R; Kaakinen M; Vuolteenaho R; Herva R; Vieira P; Dunder T; Kokkonen H; Moilanen JS; Rantala H; Nogee LM; Majewski J; Rämet M; Hallman M; Hinttala R
[Ad] Address:PEDEGO Research Unit and Medical Research Center Oulu, University of Oulu and Oulu University Hospital, PO Box 5000, 90014, Oulu, Finland. johanna.uusimaa@oulu.fi.
[Ti] Title:NHLRC2 variants identified in patients with fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA): characterisation of a novel cerebropulmonary disease.
[So] Source:Acta Neuropathol;, 2018 Feb 08.
[Is] ISSN:1432-0533
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:A novel multi-organ disease that is fatal in early childhood was identified in three patients from two non-consanguineous families. These children were born asymptomatic but at the age of 2 months they manifested progressive multi-organ symptoms resembling no previously known disease. The main clinical features included progressive cerebropulmonary symptoms, malabsorption, progressive growth failure, recurrent infections, chronic haemolytic anaemia and transient liver dysfunction. In the affected children, neuropathology revealed increased angiomatosis-like leptomeningeal, cortical and superficial white matter vascularisation and congestion, vacuolar degeneration and myelin loss in white matter, as well as neuronal degeneration. Interstitial fibrosis and previously undescribed granuloma-like lesions were observed in the lungs. Hepatomegaly, steatosis and collagen accumulation were detected in the liver. A whole-exome sequencing of the two unrelated families with the affected children revealed the transmission of two heterozygous variants in the NHL repeat-containing protein 2 (NHLRC2); an amino acid substitution p.Asp148Tyr and a frameshift 2-bp deletion p.Arg201GlyfsTer6. NHLRC2 is highly conserved and expressed in multiple organs and its function is unknown. It contains a thioredoxin-like domain; however, an insulin turbidity assay on human recombinant NHLRC2 showed no thioredoxin activity. In patient-derived fibroblasts, NHLRC2 levels were low, and only p.Asp148Tyr was expressed. Therefore, the allele with the frameshift deletion is likely non-functional. Development of the Nhlrc2 null mouse strain stalled before the morula stage. Morpholino knockdown of nhlrc2 in zebrafish embryos affected the integrity of cells in the midbrain region. This is the first description of a fatal, early-onset disease; we have named it FINCA disease based on the combination of pathological features that include fibrosis, neurodegeneration, and cerebral angiomatosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[St] Status:Publisher
[do] DOI:10.1007/s00401-018-1817-z

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[PMID]: 29256416
[Au] Autor:Dakovic Bacalja I; Nikolic I; Pavic P; Krpina K; Diklic D; Sola I; Hudorovic N; Bacalja J
[Ad] Address:Department of Vascular Surgery, General Hospital Bjelovar, Bjelovar, Croatia.
[Ti] Title:Solitary mediastinal angiomatosis: report of two cases and review of the literature.
[So] Source:Neth J Med;75(10):455-457, 2017 Dec.
[Is] ISSN:1872-9061
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Angiomatosis is a rare benign vascular lesion, usually seen in females in the first two decades of life. It commonly involves the lower extremities. Angiomatosis of mediastinum is very rare and we report two such cases with a review of the literature on solitary mediastinal angiomatosis. Both of our patients were female, aged 34 and 57 years. One patient presented with left-sided subcutaneous supraclavicular swelling. Magnetic resonance imaging showed a mass extending from the left upper mediastinum to the left supraclavicular area. The other patient presented with pleural effusion. Computed tomography of the chest disclosed an infiltrative mass in the mediastinum. Both patients were treated by excision of the lesions, histologically confirmed to be angiomatosis. Despite the rarity of mediastinal angiomatosis, this clinicopathological entity must be taken into consideration when the treatment of mediastinal tumours is planned.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171219
[Lr] Last revision date:171219
[St] Status:In-Process

  9 / 7284 MEDLINE  
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[PMID]: 29217070
[Au] Autor:Goss JA; Greene AK
[Ad] Address:Department of Plastic and Oral Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue Boston, MA, 02115, USA.
[Ti] Title:Congenital Vascular Tumors.
[So] Source:Otolaryngol Clin North Am;51(1):89-97, 2018 Feb.
[Is] ISSN:1557-8259
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, congestive heart failure, and death. Vascular tumors should be differentiated from vascular malformations, which present at birth, have a quiescent endothelium, and grow in proportion to the child. Together, vascular tumors and malformations comprise the field of vascular anomalies.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1712
[Cu] Class update date: 171208
[Lr] Last revision date:171208
[St] Status:In-Process

  10 / 7284 MEDLINE  
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[PMID]: 29197842
[Au] Autor:Pontré JC; Ojedo V; McElhinney B
[Ad] Address:King Edward Memorial Hospital for Women, Subiaco, Western Australia, Australia.
[Ti] Title:Angiomatosis of the uterus, cervix and fallopian tubes: a rare and benign cause of intractable, heavy menstrual bleeding.
[So] Source:BMJ Case Rep;2017, 2017 Dec 02.
[Is] ISSN:1757-790X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Angiomatosis of the uterus, cervix and fallopian tubes is a rare and benign entity that has not been reported in the literature previously. We present a case of a 27-year-old patient with severe and intractable heavy menstrual bleeding unresponsive to all conservative and conventional forms of treatment. Following a laparoscopic hysterectomy, the histopathological finding of angiomatosis, a vascular abnormality in the uterus, cervix and fallopian tubes, provided a plausible explanation in this situation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171203
[Lr] Last revision date:171203
[St] Status:In-Process


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