Database : MEDLINE
Search on : Aortitis [Words]
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[PMID]: 29403335
[Au] Autor:Wong SH; Turbin RE; Frohman LP
[Ad] Address:Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark.
[Ti] Title:Takayasu arteritis-related photic and postprandial amaurosis.
[So] Source:Digit J Ophthalmol;23(4):13-14, 2017.
[Is] ISSN:1542-8958
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We report the case of a 66-year-old man with Takayasu arteritis who developed photic and postprandial amaurosis occurring at a corticosteroid dose <40 mg per day, despite concurrent methotrexate. The amaurosis resolved with correction of anemia by packed red blood cell transfusion. Marginal retinal perfusion in Takayasu arteritis may precipitate symptomatic hypoxia as a result of eating a meal or exposing the eye to bright lights. Correction of anemia improves oxygen delivery to the hypoxic retina and relieves recurrent amaurosis.
[Mh] MeSH terms primary: Blindness/etiology
Postprandial Period
Takayasu Arteritis/complications
[Mh] MeSH terms secundary: Aged
Axillary Artery/diagnostic imaging
Blindness/diagnosis
Blindness/physiopathology
Diagnosis, Differential
Fluorescein Angiography/methods
Fundus Oculi
Humans
Magnetic Resonance Angiography
Male
Retinal Vessels/diagnostic imaging
Subclavian Artery/diagnostic imaging
Takayasu Arteritis/diagnosis
Visual Acuity
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180207
[St] Status:MEDLINE
[do] DOI:10.5693/djo.02.2017.09.002

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[PMID]: 29397599
[Au] Autor:Chen Z; Yang YJ; Li J; Tian XP
[Ad] Address:Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China.
[Ti] Title:[The clinical characteristics of Takayasu's arteritis with glomerulonephropathy].
[So] Source:Zhonghua Nei Ke Za Zhi;57(2):129-133, 2018 Feb 01.
[Is] ISSN:0578-1426
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To investigate the clinical features of Takayasu's arteritis (TAK) with glomerulonephropathy and to improve physicians' understanding of this complication in patients with TAK. Clinical data were retrospectively collected including manifestations, laboratory tests, image findings and treatment of 8 patients diagnosed as Takayasu's arteritis with glomerulonephropathy from January 2002 to January 2017 in Peking Union Medical College Hospital. Glomerulonephropathy was confirmed based on percutaneous renal biopsy. There were 6 women and 2 men. The median onset age and median disease duration were 24 (18-37) years and 42 (3-360) months, respectively. Five patients had hypertension. The 24 hour urinary protein was 0.18-14.91 g. Red blood cells and casts in urine were tested among 4 and 2 patients, respectively. Three patients had renal artery stenosis. Three patients demonstrated mesangial proliferative glomerulonephritis, two with IgA nephropathy, two with minimal change disease and one with membranoproliferative glomerulonephritis. Seven patients received glucocorticoid combined with cyclophosphamide therapy (glucocorticoid 40-60 mg/d, prednisone or equivalent; cyclophosphamide 0.4 g/week iv. or cyclophosphamide 0.1 g/d po.). Uninary blood cells removed and 24 hour urinary protein decreased from 1.65 g to 0.90 g after treatment for 12 months in one patient. The other 7 patients were missing. Glomerulonephropathy is occasionally observed among TAK patients. Mesangial proliferative glomerulonephritis is the most common pathological subtype. Glucocorticoid combined with cyclophosphamide therapy could be an optional therapy for Takayasu's arteritis with glomerulonephropathy.
[Mh] MeSH terms primary: Glomerulonephritis, Membranoproliferative/etiology
Glomerulonephritis/etiology
Takayasu Arteritis/pathology
[Mh] MeSH terms secundary: Adolescent
Adult
Cyclophosphamide/administration & dosage
Cyclophosphamide/therapeutic use
Erythrocytes
Female
Glomerulonephritis/pathology
Glomerulonephritis, IGA
Glomerulonephritis, Membranoproliferative/pathology
Glucocorticoids/administration & dosage
Glucocorticoids/therapeutic use
Humans
Hypertension
Male
Prednisone/administration & dosage
Prednisone/therapeutic use
Takayasu Arteritis/complications
Takayasu Arteritis/drug therapy
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Glucocorticoids); 8N3DW7272P (Cyclophosphamide); VB0R961HZT (Prednisone)
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180206
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0578-1426.2018.02.009

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[PMID]: 29208247
[Au] Autor:de la Rocha JAL; Espinoza LR
[Ad] Address:Department of Internal Medicine, Section of Rheumatology, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
[Ti] Title:Assessing the Risk of Aortic Aneurysm in Takayasu Arteritis.
[So] Source:Am J Med Sci;354(6):531-532, 2017 12.
[Is] ISSN:1538-2990
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Aortic Aneurysm/diagnosis
Inflammation Mediators
Takayasu Arteritis/diagnosis
[Mh] MeSH terms secundary: Aortic Aneurysm/blood
Aortic Aneurysm/epidemiology
Biomarkers/blood
Humans
Inflammation Mediators/blood
Risk Factors
Takayasu Arteritis/blood
Takayasu Arteritis/epidemiology
[Pt] Publication type:EDITORIAL
[Nm] Name of substance:0 (Biomarkers); 0 (Inflammation Mediators)
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:171207
[St] Status:MEDLINE

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[PMID]: 29492609
[Au] Autor:Curtis W; Yano M
[Ad] Address:Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8131, St. Louis, MO, 63110, USA. curtisw@mir.wustl.edu.
[Ti] Title:Acute non-traumatic disease of the abdominal aorta.
[So] Source:Abdom Radiol (NY);, 2018 Mar 01.
[Is] ISSN:2366-0058
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Acute pathology in the abdominal aorta is associated with significant morbidity and mortality. The most feared complication of abdominal aortic disease is acute rupture in the setting of atherosclerotic abdominal aortic aneurysm. Although frank rupture often is easily diagnosed on CT, other findings such as a hyperattenuating crescent, discontinuous intimal calcium, and draping of the aorta are subtle signs of aneurysm instability. A true aneurysm should be distinguished from a rapidly growing, saccular pseudoaneurysm in the setting of infectious aortitis, as treatment strategy differs. Acute aortic syndrome involving the abdominal aorta, such as dissection and intramural hematoma, often is an extension of thoracic aortic disease, whereas penetrating atherosclerotic ulcers occasionally involve only the abdominal aorta. The goal of treating acute aortic pathology is to repair and prevent rupture, as well as restore and maintain perfusion of the lower extremities, kidneys, and mesentery. However, both open and endovascular repair of the abdominal aorta may become acutely complicated, resulting in compromise of these goals. Examples include aortoenteric fistula, endoleak, anastomotic pseudoaneurysm, graft infection, and thrombosis or kinking of a stent graft resulting in ischemia of the limbs and mesentery.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[St] Status:Publisher
[do] DOI:10.1007/s00261-018-1525-0

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[PMID]: 29489984
[Au] Autor:Colodetti R; Spina G; Leal T; Oliveira M; Soeiro A
[Ad] Address:Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
[Ti] Title:Cogan's syndrome - A rare aortitis, difficult to diagnose but with therapeutic potential.
[So] Source:Rev Assoc Med Bras (1992);63(12):1028-1031, 2017 Dec.
[Is] ISSN:1806-9282
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:The inflammation of aortic wall, named aortitis, is a rare condition that can be caused by a number of pathologies, mainly inflammatory or infectious in nature. In this context, the occurrence of combined audiovestibular and/or ocular manifestations eventually led to the diagnosis of Cogan's syndrome, making it the rare case, but susceptible to adequate immunosuppressive treatment and satisfactory disease control.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180228
[Lr] Last revision date:180228
[St] Status:In-Process

  6 / 11033 MEDLINE  
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[PMID]: 29408476
[Au] Autor:De Worm S; Giot JB; Courtoy C; Gillet E; Amrane S; Huynen P; Van Esbroeck M; Prudent E; Lepidi H; Million M; Moutschen M; Raoult D
[Ad] Address:Internal General Medicine and Infectious Diseases, CHU de Liège, 4000 Liège. Belgium.
[Ti] Title:A case of giant cell arteritis associated with a culture proven Coxiella burnetii aortitis.
[So] Source:Int J Infect Dis;, 2018 Feb 23.
[Is] ISSN:1878-3511
[Cp] Country of publication:Canada
[La] Language:eng
[Ab] Abstract:We report a case of proven Coxiella burnetii aortitis, possibly associated with a giant cell arteritis (GCA). A seventy-two-year-old man, who is a hunter, presented with weight loss, fevers, jaw claudication and hardened temporal arteries associated with a persistent inflammatory syndrome and an arteritis of the whole aorta including the brachiocephalic arteries on the 18F-FDG PET/CT. A diagnosis of GCA was retained and a treatment with prednisolone was started. Given an aneurysm of the abdominal aorta, the patient underwent replacement of abdominal aorta with an allograft. Histology showed an intense chronic arteritis attributed to atherosclerosis with dissection. However, Coxiella burnetii infection was confirmed by serology and then by culture and molecular biology on the surgical piece. A combination of hydroxychloroquine and doxycycline was added to tapered prednisolone with a favorable outcome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:Publisher

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[PMID]: 29472288
[Au] Autor:García-Arribas D; Vilacosta I; Ortega Candil A; Rodríguez Rey C; Olmos C; Pérez Castejón MJ; Vivas D; Pérez-García CN; Carnero-Alcázar M; Fernández-Pérez C; Maroto L; Carreras JL
[Ad] Address:Instituto Cardiovascular, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdSSC), Madrid, Spain.
[Ti] Title:Usefulness of positron emission tomography/computed tomography in patients with valve-tube graft infection.
[So] Source:Heart;, 2018 Feb 22.
[Is] ISSN:1468-201X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Infection of valved aortic grafts is a rare entity whose diagnosis remains challenging. Positron emission tomography (PET)/CT has become a criterion for the diagnosis of infective endocarditis (IE) in prosthetic valves, but its role on ascending aortic graft infections remains unclear. This study aims to assess the diagnostic value of PET/CT in patients with valved aortic graft infection. METHODS: 12 episodes with a valved aortic graft who had undergone a PET/CT due to suspicion of IE were prospectively included (group I) and compared with five controls free of infection who underwent PET/CT for other reasons (group II). Pathological uptake of F-fluorodeoxyglucose (FDG) and its pattern at the prosthetic valve and aortic graft were studied. RESULTS: Diagnosis of IE was confirmed in 9 out of 12 episodes of group I. F-FDG uptake was detectable in eight out of nine cases with a final diagnosis of IE. The most repeated pattern of uptake was homogeneous around the valve and heterogeneous around the tube. There was one false-negative study. Of the three patients in which IE was ruled out, there were two false positives and one true negative. In group II, there were three patients with a positive PET/CT study, two of them had active aortitis and the third was considered false positive. CONCLUSIONS: F-FDG PET/CT shows high sensitivity in the detection of infected aortic grafts. Thus, this technique should be considered in the diagnostic work-up of patients with suspicion of aortic graft infection. However, further validation of this approach is needed.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180223
[Lr] Last revision date:180223
[St] Status:Publisher

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[PMID]: 29208249
[Au] Autor:Yang KQ; Meng X; Zhang Y; Fan P; Wang LP; Zhang HM; Wu HY; Jiang XJ; Cai J; Zhou XL; Hui RT; Zheng DY; Liu LS
[Ad] Address:Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
[Ti] Title:Aortic Aneurysm in Takayasu Arteritis.
[So] Source:Am J Med Sci;354(6):539-547, 2017 12.
[Is] ISSN:1538-2990
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Aortic aneurysm (AA) is a severe complication of Takayasu arteritis (TA). This study aimed to evaluate the prevalence, clinical and imaging features, management and long-term outcomes of AA in patients with TA. MATERIALS AND METHODS: A retrospective study was performed of TA patients with AA admitted to Fuwai Hospital from 1996-2015. Baseline clinical data and follow-up data of TA patients with AA were collected and analyzed. RESULTS: Thirty-nine (4.2%) of 934 patients with TA were identified with AA that was related to vasculitis. The mean age at disease onset was 31 ± 10 years, with a female-to-male ratio of 1.79:1. The ascending aorta was the most common site of the aneurysmal lesion (18, 33.3%), and the most frequent manifestations associated with AA were chest tightness (12, 30.8%) and shortness of breath (12, 30.8%), which were usually concomitant with aortic valve insufficiency. Involvement of multiple sites in AA was found in 8 patients (20.5%), and multiple AAs were found in 5 patients (12.8%). No significant difference was observed in clinical and imaging findings between sexes. Of 25 patients (64.1%) with a median 72-month follow-up, 1 patient suffered from heart failure owing to perivalvular leakage, and 1 patient died, possibly related to severe complications of the operation. CONCLUSIONS: The prevalence of AA is relatively low in Chinese patients with TA. AA seems to develop more frequently in male patients with TA. Management should consider location and size of AA, complexity of vessel lesions and disease status. Long-term follow-up is indispensable.
[Mh] MeSH terms primary: Aortic Aneurysm/etiology
Takayasu Arteritis/complications
[Mh] MeSH terms secundary: Adult
Aortic Aneurysm/diagnosis
Aortic Aneurysm/epidemiology
Aortic Aneurysm/pathology
Chest Pain/etiology
Computed Tomography Angiography
Dyspnea/etiology
Female
Humans
Male
Prevalence
Retrospective Studies
Sex Factors
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1712
[Cu] Class update date: 180223
[Lr] Last revision date:180223
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:171207
[St] Status:MEDLINE

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[PMID]: 29427822
[Au] Autor:de Boysson H; Daumas A; Vautier M; Parienti JJ; Liozon E; Lambert M; Samson M; Ebbo M; Dumont A; Sultan A; Bonnotte B; Manrique A; Bienvenu B; Saadoun D; Aouba A
[Ad] Address:Department of Internal Medicine, Caen University Hospital, Caen, France; University of Normandy, Caen, France. Electronic address: deboysson-h@chu-caen.fr.
[Ti] Title:Large-vessel involvement and aortic dilation in giant-cell arteritis. A multicenter study of 549 patients.
[So] Source:Autoimmun Rev;, 2018 Feb 07.
[Is] ISSN:1873-0183
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Large-vessel involvement (LVI) can occur in giant-cell arteritis (GCA) and may represent a distinct disease subgroup with a higher risk for aortic dilation. This study aimed to better characterize the presentation and evolution of LVI in patients with GCA. PATIENTS AND METHODS: A retrospective multicenter study enrolled 248 GCA patients with LVI and 301 GCA patients without LVI on imaging. Factors associated with aortic dilation were identified in a multivariable model. RESULTS: The patients with LVI were younger (p<0.0001), more likely to be women (p=0.01), and showed fewer cephalic symptoms (p<0.0001) and polymyalgia rheumatica (p=0.001) but more extracranial vascular symptoms (p=0.05) than the patients without LVI. Glucocorticoids (GC) management did not differ between the two groups, but the GC discontinuation rate was lower in the patients with LVI (p=0.0003). Repeated aortic imaging procedures were performed at 19months [range: 5-162months] and 17months [range: 6-168months] after diagnosis in 154 patients with LVI and 123 patients without LVI, respectively, of whom 21% and 7%, respectively, presented new aortic dilations (p=0.0008). In the patients with LVI, aortic dilation occurred on an aorta segment shown to be inflammatory on previous imaging in 94% of patients. In the multivariate analysis, LVI was the strongest predictor of aortic dilation (hazard ratio: 3.16 [range: 1.34-7.48], p=0.009). CONCLUSIONS: LVI represents a distinct disease pattern of GCA with an increased risk of aortic dilation. Control of the aortic morphology during follow-up is required.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1802
[Cu] Class update date: 180218
[Lr] Last revision date:180218
[St] Status:Publisher

  10 / 11033 MEDLINE  
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[PMID]: 29249489
[Au] Autor:Tanaka A; Estrera AL
[Ad] Address:Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston and Memorial Hermann Hospital, Houston, Tex.
[Ti] Title:Infectious aortitis: A bridge too far.
[So] Source:J Thorac Cardiovasc Surg;155(3):e93-e94, 2018 Mar.
[Is] ISSN:1097-685X
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:EDITORIAL
[Em] Entry month:1712
[Cu] Class update date: 180217
[Lr] Last revision date:180217
[St] Status:In-Data-Review


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