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[PMID]: 27778425
[Au] Autor:Admani S; Goldenberg A; Jacob SE
[Ad] Address:Department of Dermatology, University of California, San Diego, La Jolla, California.
[Ti] Title:Contact Alopecia: Improvement of Alopecia with Discontinuation of Fluocinolone Oil in Individuals Allergic to Balsam Fragrance.
[So] Source:Pediatr Dermatol;34(1):e57-e60, 2017 Jan.
[Is] ISSN:1525-1470
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Inflammatory scalp dermatoses can be associated with alopecia, which is nonscarring and reversible in its early stages. This association has been described in seborrheic dermatitis, psoriasis, and atopic dermatitis. We describe three girls with alopecia aggravated by contact allergy to balsam fragrances. All three had complete resolution with avoidance of balsam of Peru and other balsam derivatives (including discontinuation of fluocinolone oil, which contains balsam of pine).
[Mh] MeSH terms primary: Allergens/adverse effects
Alopecia/chemically induced
Balsams/adverse effects
Dermatitis, Allergic Contact/etiology
Perfume/adverse effects
[Mh] MeSH terms secundary: Adolescent
Alopecia/diagnosis
Child, Preschool
Dermatitis, Allergic Contact/diagnosis
Female
Humans
Patch Tests
[Pt] Publication type:CASE REPORTS
[Nm] Name of substance:0 (Allergens); 0 (Balsams); 0 (Perfume); 8P5F881OCY (Peruvian balsam)
[Em] Entry month:1704
[Cu] Class update date: 180207
[Lr] Last revision date:180207
[Js] Journal subset:IM
[Da] Date of entry for processing:161026
[St] Status:MEDLINE
[do] DOI:10.1111/pde.13011

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[PMID]: 28107743
[Au] Autor:Xin X; Zhong N; Liao Q; Cen Y; Wu R; Wang Z
[Ad] Address:Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China.
[Ti] Title:High-sensitivity four-layer polymer fiber-optic evanescent wave sensor.
[So] Source:Biosens Bioelectron;91:623-628, 2017 May 15.
[Is] ISSN:1873-4235
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:We present a novel four-layer structure consisting of bottom, second, third, and surface layers in the sensing region, for a D-shaped step-index fiber-optic evanescent wave (FOEW) sensor. To reduce the background noise, the surface of the longitudinal section in the D-shaped region is coated with a light-absorbing film. We check the morphologies of the second and surface layers, examine the refractive indices (RIs) of the third and surface layers, and analyze the composition of the surface layer. We also investigate the effects of the thicknesses and RIs of the third and surface layers and the LA film on the light transmission and sensitivity of the FOEW sensors. The results highlight the very good sensitivity of the proposed FOEW sensor with a four-layer structure, which reached -0.077 (µg/l) in the detection of the target antibody; the sensitivity of the novel FOEW sensor was 7.60 and 1.52 times better than that of a conventional sensor with a core-cladding structure and an FOEW sensor with a three-layer structure doped with GeO . The applications of this high-sensitivity FOEW sensor can be extended to biodefense, disease diagnosis, and biomedical and biochemical analysis.
[Mh] MeSH terms primary: Biosensing Techniques/instrumentation
Fiber Optic Technology/instrumentation
Optical Fibers
Polymers/chemistry
[Mh] MeSH terms secundary: Animals
Antibodies, Anti-Idiotypic/analysis
Antibodies, Anti-Idiotypic/immunology
Balsams/chemistry
Drug Combinations
Equipment Design
Germanium/chemistry
Goats
Gutta-Percha/chemistry
Immunoglobulin G/analysis
Immunoglobulin G/immunology
Mice
Zinc Oxide/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Antibodies, Anti-Idiotypic); 0 (Balsams); 0 (Drug Combinations); 0 (Immunoglobulin G); 0 (Polymers); 00072J7XWS (Germanium); 5O6CM4W76A (germanium oxide); 78170-65-7 (Kloroperka); 9000-32-2 (Gutta-Percha); SOI2LOH54Z (Zinc Oxide)
[Em] Entry month:1703
[Cu] Class update date: 170531
[Lr] Last revision date:170531
[Js] Journal subset:IM
[Da] Date of entry for processing:170121
[St] Status:MEDLINE

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[PMID]: 28330330
[Au] Autor:Shajitha PP; Dhanesh NR; Ebin PJ; Laly J; Aneesha D; Reshma J; Augustine J; Linu M
[Ad] Address:School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, 686 560, India.
[Ti] Title:A combined chloroplast atpB-rbcL and trnL-F phylogeny unveils the ancestry of balsams (Impatiens spp.) in the Western Ghats of India.
[So] Source:3 Biotech;6(2):258, 2016 Dec.
[Is] ISSN:2190-572X
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Only a few Impatiens spp. from South India (one of the five centers of diversity for Impatiens species) were included in the published datum of molecular phylogeny of the family Balsaminaceae. The present investigation is a novel attempt to reveal the phylogenetic association of Impatiens species of South India, by placing them in the global phylogeny of Impatiens based on a combined analysis of two chloroplast genes. Thirty species of genus Impatiens were collected from different locations of South India. Total genomic DNA was extracted from fresh plant leaf, and polymerase chain reaction was carried out using atpB-rbcL and trnL-F intergenic spacer-specific forward and reverse primers. Thirteen sequences of Impatiens species from three centers of diversity were obtained from GenBank for reconstructing the evolutionary relationships within the genus Impatiens. Bayesian inference analysis was carried out in MrBayes v.3.2.2. This analysis supported Southeast Asia as the ancestral place of origin of extant Impatiens species. Molecular phylogeny of South Indian Impatiens spp. based on combined chloroplast sequences showed the same association as that of morphological taxonomy. Sections Scapigerae, Tomentosae, Sub-Umbellatae, and Racemosae showed Southeast Asian relationship, while sections Annuae and Microsepalae showed African affinity.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1703
[Cu] Class update date: 170816
[Lr] Last revision date:170816
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1007/s13205-016-0574-8

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[PMID]: 27279325
[Au] Autor:Tempark T; Chatproedprai S; Wananukul S
[Ad] Address:Department of Pediatrics, Chulalongkorn University, Bangkok, Thailand.
[Ti] Title:Localized contact dermatitis from Ferula assa-foetida oleo-gum-resin essential oil, a traditional topical preparation for stomach ache and flatulence.
[So] Source:Indian J Dermatol Venereol Leprol;82(4):467, 2016 Jul-Aug.
[Is] ISSN:0973-3922
[Cp] Country of publication:India
[La] Language:eng
[Mh] MeSH terms primary: Abdominal Pain/drug therapy
Balsams/adverse effects
Dermatitis, Contact/diagnosis
Ferula
Flatulence/drug therapy
Oils, Volatile/adverse effects
[Mh] MeSH terms secundary: Abdominal Pain/diagnosis
Balsams/administration & dosage
Coumarins/administration & dosage
Coumarins/adverse effects
Flatulence/diagnosis
Humans
Infant
Oils, Volatile/administration & dosage
Sesquiterpenes/administration & dosage
Sesquiterpenes/adverse effects
[Pt] Publication type:LETTER
[Nm] Name of substance:0 (Balsams); 0 (Coumarins); 0 (Oils, Volatile); 0 (Sesquiterpenes); 0 (assafoetidnol A); 0 (copaiba balsam)
[Em] Entry month:1704
[Cu] Class update date: 170406
[Lr] Last revision date:170406
[Js] Journal subset:IM
[Da] Date of entry for processing:160610
[St] Status:MEDLINE
[do] DOI:10.4103/0378-6323.182969

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[PMID]: 27211689
[Au] Autor:Burger P; Casale A; Kerdudo A; Michel T; Laville R; Chagnaud F; Fernandez X
[Ad] Address:Institut de Chimie de Nice (ICN), UMR CNRS 7272, Parc Valrose, 06108 Nice Cedex 2, France. Electronic address: Pauline.BURGER@unice.fr.
[Ti] Title:New insights in the chemical composition of benzoin balsams.
[So] Source:Food Chem;210:613-22, 2016 Nov 01.
[Is] ISSN:0308-8146
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Benzoin balsam is an anthropic exudate obtained from the bark of several species of Styrax trees that is mainly used as a perfume fixative as well as a flavouring agent. Benzoe tonkinensis Laos (also commercialized under the denomination Siam benzoin balsam) displaying characteristic vanilla notes and already being largely used to flavour all kinds of edible goods, was intended to be proposed by Agroforex Company to the Codex Committee on Food Additives for evaluation as a food additive. For this purpose, the present paper reports the phytochemical characterisation of both the volatile and non-volatile fractions of benzoin balsams and the quantitation of some of the major components by gas and liquid chromatography techniques. Four coniferyl and two morinol derivatives were characterised for the first time in Benzoe tonkinensis Laos. Finally, two liquid chromatographic methods used to easily discriminate Siam from Sumatra balsam (also known as Benzoe sumatranus Indonesia) were developed.
[Mh] MeSH terms primary: Balsams/analysis
Balsams/chemistry
Styrax/chemistry
[Mh] MeSH terms secundary: Flavoring Agents
Food Additives
Indonesia
Perfume
Plant Bark/chemistry
Thailand
Volatile Organic Compounds/analysis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Balsams); 0 (Flavoring Agents); 0 (Food Additives); 0 (Perfume); 0 (Volatile Organic Compounds)
[Em] Entry month:1701
[Cu] Class update date: 170118
[Lr] Last revision date:170118
[Js] Journal subset:IM
[Da] Date of entry for processing:160524
[St] Status:MEDLINE

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[PMID]: 27127058
[Au] Autor:de Almeida Borges VR; da Silva JH; Barbosa SS; Nasciutti LE; Cabral LM; de Sousa VP
[Ad] Address:Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
[Ti] Title:Development and pharmacological evaluation of in vitro nanocarriers composed of lamellar silicates containing copaiba oil-resin for treatment of endometriosis.
[So] Source:Mater Sci Eng C Mater Biol Appl;64:310-317, 2016 Jul 01.
[Is] ISSN:1873-0191
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:In this work, newly developed nanocomposites based upon lamellar silicates are evaluated to determine their potential in controlling endometriosis. The preparation of the new nanocarriers is detailed, properties characterized and in vitro pharmacological evaluation performed. The nanocomposites in this study were obtained from the reaction of copaiba oil-resin (COPA) with the polymer polyvinylpyrrolidone (PVP K-30). COPA was selected due to its antiinflammatory and anticancer activities along with the organophilic derivatives of sodium montmorillonite, Viscogel B8, S7 and S4. The results indicated that it was feasible to obtain a good yield of a COPA nanocomposite using a simple process. Intercalation was confirmed by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). In vitro release experiments demonstrated that COPA was released from the nanocomposite in a delayed fashion. Whereas, in vitro pharmacological studies showed a reduction in viability and proliferation of endometriotic cell cultures upon COPA nanocomposite treatment, suggesting that the system developed here can be a promising alternative therapy for the oral treatment of endometriosis.
[Mh] MeSH terms primary: Balsams
Drug Carriers
Endometriosis/drug therapy
Endometrium/metabolism
Nanocomposites/chemistry
Silicates
[Mh] MeSH terms secundary: Balsams/chemistry
Balsams/pharmacology
Cells, Cultured
Drug Carriers/chemistry
Drug Carriers/pharmacology
Endometriosis/metabolism
Endometrium/pathology
Female
Humans
Silicates/chemistry
Silicates/pharmacology
Stromal Cells/metabolism
Stromal Cells/pathology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Balsams); 0 (Drug Carriers); 0 (Silicates); 0 (copaiba balsam)
[Em] Entry month:1703
[Cu] Class update date: 170805
[Lr] Last revision date:170805
[Js] Journal subset:IM
[Da] Date of entry for processing:160430
[St] Status:MEDLINE

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[PMID]: 26661909
[Au] Autor:Norlén L
[Ad] Address:Dermatology Clinic, Department of Medicine and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm. E-mail: lars.norlen@ki.se.
[Ti] Title:Is Oil a Balsam for Baby Skin?
[So] Source:Acta Derm Venereol;96(3):291, 2016 Mar.
[Is] ISSN:1651-2057
[Cp] Country of publication:Sweden
[La] Language:eng
[Mh] MeSH terms primary: Balsams
Skin
[Mh] MeSH terms secundary: Humans
[Pt] Publication type:COMMENT; JOURNAL ARTICLE
[Nm] Name of substance:0 (Balsams)
[Em] Entry month:1608
[Cu] Class update date: 160301
[Lr] Last revision date:160301
[Js] Journal subset:IM
[Da] Date of entry for processing:151215
[St] Status:MEDLINE
[do] DOI:10.2340/00015555-2313

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[PMID]: 26500253
[Au] Autor:Urban N; Wang L; Kwiek S; Rademann J; Kuebler WM; Schaefer M
[Ad] Address:Rudolf-Boehm-Institut für Pharmakologie und Toxikologie, Universität Leipzig, Leipzig, Germany (N.U., M.S.); Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany (S.K., J.R.); and The Keenan Research Centre of St. Michael's Hospital, Toronto, Canada (L.W., W.M.K.).
[Ti] Title:Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
[So] Source:Mol Pharmacol;89(1):197-213, 2016 Jan.
[Is] ISSN:1521-0111
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Classical or canonical transient receptor potential 6 (TRPC6), a nonselective and Ca(2+)-permeable cation channel, mediates pathophysiological responses within pulmonary and renal diseases that are still poorly controlled by current medication. Thus, controlling TRPC6 activity may provide a promising and challenging pharmacological approach. Recently identified chemical entities have demonstrated that TRPC6 is pharmacologically targetable. However, isotype-selectivity with regard to its closest relative, TRPC3, is difficult to achieve. Reasoning that balsams, essential oils, or incense materials that are traditionally used for inhalation may contain biologic activities to block TRPC6 activity, we embarked on a natural compound strategy to identify new TRPC6-blocking chemical entities. Within several preparations of plant extracts, a strong TRPC6-inhibitory activity was found in conifer balsams. The biologic activity was associated with nonvolatile resins, but not with essential oils. Of various conifers, the larch balsam was unique in displaying a marked TRPC6-prevalent mode of action. By testing the main constituents of larch resin, we identified larixol and larixyl acetate as blockers of Ca(2+) entry and ionic currents through diacylglycerol- or receptor-activated recombinant TRPC6 channels, exhibiting approximately 12- and 5-fold selectivity compared with its closest relatives TRPC3 and TRPC7, respectively. No significant inhibition of more distantly related TRPV or TRPM channels was seen. The potent inhibition of recombinant TRPC6 by larixyl acetate (IC50 = 0.1-0.6 µM) was confirmed for native TRPC6-like [Ca(2+)]i signals in diacylglycerol-stimulated rat pulmonary artery smooth muscle cells. In isolated mouse lungs, larix-6-yl monoacetate (CAS 4608-49-5; larixyl acetate; 5 µM) prevented acute hypoxia-induced vasoconstriction. We conclude that larch-derived labdane-type diterpenes are TRPC6-selective inhibitors and may represent a starting point for pharmacological TRPC6 modulation within experimental therapies.
[Mh] MeSH terms primary: Larix
Plant Extracts/isolation & purification
Plant Extracts/pharmacology
Plant Oils/isolation & purification
Plant Oils/pharmacology
TRPC Cation Channels/antagonists & inhibitors
[Mh] MeSH terms secundary: Animals
Cells, Cultured
HEK293 Cells
Humans
Male
Mice
Mice, Inbred C57BL
Myocytes, Smooth Muscle/drug effects
Myocytes, Smooth Muscle/metabolism
Rats
TRPC6 Cation Channel
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; VALIDATION STUDIES
[Nm] Name of substance:0 (Plant Extracts); 0 (Plant Oils); 0 (TRPC Cation Channels); 0 (TRPC6 Cation Channel); 0 (TRPC6 protein, human)
[Em] Entry month:1603
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:151027
[St] Status:MEDLINE
[do] DOI:10.1124/mol.115.100792

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[PMID]: 26551611
[Au] Autor:Hill H; Jacob SE
[Ad] Address:MSIV Loma Linda University School of Medicine Loma Linda, CA Department of Dermatology Loma Linda University Loma Linda, CA From the *Loma Linda University School of Medicine, and †Department of Dermatology, Loma Linda University, Loma Linda, CA.
[Ti] Title:Peri-Anal Ulcerations in a Patient With Essential Pruritus.
[So] Source:Dermatitis;26(6):292-3, 2015 Nov-Dec.
[Is] ISSN:2162-5220
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Balsams/adverse effects
Dermatitis, Allergic Contact/etiology
Dermatologic Agents/adverse effects
Eugenol/adverse effects
Skin Cream/adverse effects
Skin Ulcer/chemically induced
[Mh] MeSH terms secundary: Aged
Buttocks
Humans
Male
Patch Tests
Pruritus Ani/drug therapy
Skin Cream/chemistry
Skin Ulcer/drug therapy
[Pt] Publication type:CASE REPORTS; LETTER
[Nm] Name of substance:0 (Balsams); 0 (Dermatologic Agents); 3T8H1794QW (Eugenol); 8P5F881OCY (Peruvian balsam)
[Em] Entry month:1608
[Cu] Class update date: 151110
[Lr] Last revision date:151110
[Js] Journal subset:IM
[Da] Date of entry for processing:151110
[St] Status:MEDLINE
[do] DOI:10.1097/DER.0000000000000140

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SciELO Brazil full text

[PMID]: 26537143
[Au] Autor:Yasojima EY; Teixeira RK; Houat Ade P; Costa FL; Yamaki VN; Feitosa-Junior DJ; Silva CA; Brito MV
[Ad] Address:Laboratório de Cirurgia Experimental, Faculdade de Medicina, Universidade Estadual do Pará, Belém, PA, Brazil.
[Ti] Title:Copaiba oil influences ventral hernia repair with Vicryl® mesh?
[So] Source:Arq Bras Cir Dig;28(3):186-9, 2015 Jul-Sep.
[Is] ISSN:2317-6326
[Cp] Country of publication:Brazil
[La] Language:eng; por
[Ab] Abstract:BACKGROUND: The use of meshes in hernia surgical repair promoted revolution in the surgical area; however, some difficulties had come, such as a large area of fibrosis, greater postoperative pain and risk of infection. The search for new substances that minimize these effects should be encouraged. Medicinal plants stand out due possible active ingredients that can act on these problems. AIM: To check the copaiba oil influence in the repair of abdominal defects in rats corrected with Vicryl(c) mesh. METHOD: Twenty-four Wistar rats were submitted to an abdominal defect and corrected with Vicryl(c) mesh. They were distributed into two groups: control and copaíba via gavage, administered for seven days after surgery. The analysis of the animals took place on 8, 15 and 22 postoperative days. It analyzed the amount of adhesions and microscopic analysis of the mesh. RESULTS: There was no statistical difference regarding the amount of adhesions. All animals had signs of acute inflammation. In the control group, there were fewer macrophages in animals of the 8th compared to other days and greater amount of necrosis on day 8 than on day 22. In the copaiba group, the number of gigantocytes increased compared to the days analyzed. CONCLUSION: Copaiba oil showed an improvement in the inflammatory response accelerating its beginning; however, did not affect the amount of abdominal adhesions or collagen fibers.
[Mh] MeSH terms primary: Balsams/therapeutic use
Hernia, Ventral/surgery
Herniorrhaphy/instrumentation
Polyglactin 910
Surgical Mesh
[Mh] MeSH terms secundary: Animals
Rats
Rats, Wistar
[Pt] Publication type:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Name of substance:0 (Balsams); 0 (copaiba balsam); 34346-01-5 (Polyglactin 910)
[Em] Entry month:1609
[Cu] Class update date: 160225
[Lr] Last revision date:160225
[Js] Journal subset:IM
[Da] Date of entry for processing:151106
[St] Status:MEDLINE


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