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Search on : Blue and Toe and Syndrome [Words]
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[PMID]: 29288001
[Au] Autor:Decker P; Galland J; Risse J; Claudin M; Mohamed S; Perrot A; Wahl D
[Ad] Address:Département de médecine interne et immunologie clinique, hôpitaux de Brabois, CHRU de Nancy, 5, rue du Morvan, 54500 Vandoeuvre-lès-Nancy, France. Electronic address: decker.paul57130@gmail.com.
[Ti] Title:Un syndrome POEMS révélé par un syndrome des orteils bleus. [A POEMS syndrome revealed by a blue toe syndrome].
[So] Source:Rev Med Interne;39(2):127-129, 2018 Feb.
[Is] ISSN:1768-3122
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:INTRODUCTION: Arterial and venous thromboses occur in almost one in five patients with POEMS syndrome and usually in macrocirculation. CASE REPORT: We report a 67-year-old male with a POEMS syndrome who presented initially with a blue toe syndrome. He complained of Raynaud's syndrome and left foot paresthesia. Physical examination showed gynecomastia, lymphadenopathies and skin lesions. Cardiovascular investigations excluded atrial fibrillation, unstable atherosclerotic lesions and vascular calcifications. Imaging studies showed diffuse osteosclerotic lesions. Monoclonal protein with lambda light chain was discovered and serum level of VEGF was increased at 2900pg/ml. CONCLUSION: This is to our knowledge the first case of thrombotic microangiopathy in POEMS syndrome without embolic cause or calciphylaxis.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180210
[Lr] Last revision date:180210
[St] Status:In-Process

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[PMID]: 29305361
[Au] Autor:Neuman R; Wabbijn M; Guillen S; Dees A
[Ad] Address:Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
[Ti] Title:Blue toe syndrome as a first sign of systemic sclerosis.
[So] Source:BMJ Case Rep;2018, 2018 Jan 05.
[Is] ISSN:1757-790X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:We describe an unusual case of blue toe syndrome as the primary and solitary manifestation of systemic sclerosis. The possible cause was long-term occupational exposure in construction work. Blue toe syndrome is a small vessel disease, characterised by the sudden development of painful, blue discolouration in one or more toes. The most common aetiology is atheroembolic disease; however, it can also appear in several conditions ranging from hypercoagulability disorders to underlying systemic diseases such as vasculitis or autoimmune diseases. Here, we describe the case of a 57-year-old man who presented with blue toe syndrome without underlying atheroembolic disease. He was found to have positive anticentromere antibodies, which indicated that systemic sclerosis was the likely primary underlying cause. An extensive systemic evaluation and a thorough physical examination revealed no other symptoms associated with systemic sclerosis. He was prescribed nifedipin and rosuvastatin, and showed complete resolution of symptoms after 3 months.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180106
[Lr] Last revision date:180106
[St] Status:In-Process

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[PMID]: 27814416
[Au] Autor:Ohata C; Imamura T
[Ad] Address:Department of Dermatology, Kurume University School of Medicine, Japan.
[Ti] Title:Painful purple toes.
[So] Source:Cutis;98(3):E8-E10, 2016 Sep.
[Is] ISSN:2326-6929
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Atherosclerosis/complications
Blue Toe Syndrome
Succinates/administration & dosage
[Mh] MeSH terms secundary: Blue Toe Syndrome/diagnosis
Blue Toe Syndrome/drug therapy
Blue Toe Syndrome/etiology
Blue Toe Syndrome/physiopathology
Diagnosis, Differential
Humans
Male
Middle Aged
Myocardial Infarction/prevention & control
Platelet Aggregation Inhibitors/administration & dosage
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Platelet Aggregation Inhibitors); 0 (Succinates); 19P708E787 (sarpogrelate)
[Em] Entry month:1704
[Cu] Class update date: 170428
[Lr] Last revision date:170428
[Js] Journal subset:IM
[Da] Date of entry for processing:161105
[St] Status:MEDLINE

  4 / 205 MEDLINE  
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[PMID]: 27552783
[Au] Autor:Lambova SN
[Ad] Address:Department of Propedeutics of Internal Medicine, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
[Ti] Title:The Place of Nailfold Capillaroscopy Among Instrumental Methods for Assessment of Some Peripheral Ischaemic Syndromes in Rheumatology.
[So] Source:Folia Med (Plovdiv);58(2):77-88, 2016 Apr-Jun.
[Is] ISSN:0204-8043
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Micro- and macrovascular pathology is a frequent finding in a number of common rheumatic diseases. Secondary Raynaud's phenomenon (RP) is among the most common symptoms in systemic sclerosis and several other systemic autoimmune diseases including a broad differential diagnosis. It should be also differential from other peripheral vascular syndromes such as embolism, thrombosis, etc., some of which lead to clinical manifestation of the blue toe syndrome. The current review discusses the instrumental methods for vascular assessments. Nailfold capillaroscopy is the only method among the imaging techniques that can be used for morphological assessment of the nutritive capillaries in the nailfold area. Laser-Doppler flowmetry and laser-Doppler imaging are methods for functional assessment of microcirculation, while thermography and plethysmography reflect both blood flow in peripheral arteries and microcirculation. Doppler ultrasound and angiography visualize peripheral arteries. The choice of the appropriate instrumental method is guided by the clinical presentation. The main role of capillaroscopy is to provide differential diagnosis between primary and secondary RP. In rheumatology, capillaroscopic changes in systemic sclerosis have been recently defined as diagnostic. The appearance of abnormal capillaroscopic pattern inherits high positive predictive value for the development of a connective tissue disease that is higher than the predictive value of antinuclear antibodies. In cases of abrupt onset of peripheral ischaemia, clinical signs of critical ischaemia, unilateral or lower limb involvement, Doppler ultrasound and angiography are indicated. The most common causes for such clinical picture that may be referred to rheumatologic consultation are the antiphospholipid syndrome, mimickers of vasculitides such as atherosclerosis with cholesterol emboli, and neoplasms.
[Mh] MeSH terms primary: Antiphospholipid Syndrome/diagnostic imaging
Peripheral Arterial Disease/diagnostic imaging
Peripheral Vascular Diseases/diagnostic imaging
Scleroderma, Systemic/diagnostic imaging
Vasculitis/diagnostic imaging
[Mh] MeSH terms secundary: Angiography
Blue Toe Syndrome/diagnostic imaging
Connective Tissue Diseases/diagnostic imaging
Humans
Laser-Doppler Flowmetry
Microscopic Angioscopy
Plethysmography
Raynaud Disease/diagnostic imaging
Rheumatology
Thermography
Ultrasonography, Doppler
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1701
[Cu] Class update date: 171127
[Lr] Last revision date:171127
[Js] Journal subset:IM
[Da] Date of entry for processing:160824
[St] Status:MEDLINE

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[PMID]: 27274647
[Au] Autor:Choi KH; Yoo J; Huh JW; Jeong YI; Kim MS; Jue MS; Park HJ
[Ad] Address:Department of Dermatology, VHS Medical Center, Seoul, Korea.
[Ti] Title:Blue Toe Syndrome as an Early Sign of Disseminated Intravascular Coagulation.
[So] Source:Ann Dermatol;28(3):400-1, 2016 Jun.
[Is] ISSN:1013-9087
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:160609
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.5021/ad.2016.28.3.400

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[PMID]: 27222884
[Au] Autor:Caravaglio J; Wheatley R; Orban M; Greenwald J
[Ad] Address:College of Medicine, University of Central Florida, Orlando, Florida.
[Ti] Title:A case of leukemia cutis presenting as blue toes in a patient with chronic lymphocytic leukemia.
[So] Source:JAAD Case Rep;2(2):186-8, 2016 Mar.
[Is] ISSN:2352-5126
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:160526
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1016/j.jdcr.2016.02.010

  7 / 205 MEDLINE  
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[PMID]: 27138317
[Au] Autor:Dizman N; Aydin Bahat K; Özkanli S; Özkök A
[Ad] Address:Department of Internal Medicine and Nephrology, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey.
[Ti] Title:Cholesterol embolization syndrome: A report of two cases.
[So] Source:Turk Kardiyol Dern Ars;44(3):251-5, 2016 Apr.
[Is] ISSN:1308-4488
[Cp] Country of publication:Turkey
[La] Language:eng
[Ab] Abstract:Cholesterol embolization syndrome (CES) is a multisystemic disease with immunological features, and a rare but an important cause of acute kidney injury (AKI) following invasive angiography. It frequently occurs in the elderly male population with extensive atherosclerosis. CES should be considered in the differential diagnosis of AKI following angiography, as prognosis and treatment are completely different from contrast-induced nephropathy. Two cases of CES that developed after invasive angiography are described in the present report. In the first case, renal biopsy was performed, and CES was diagnosed by presence of characteristic renal lesions. The second patient had blue toe syndrome and persistent renal dysfunction.
[Mh] MeSH terms primary: Acute Kidney Injury
Embolism, Cholesterol
[Mh] MeSH terms secundary: Aged
Angiography/adverse effects
Blue Toe Syndrome
Fatal Outcome
Humans
Kidney/pathology
Male
Toes/pathology
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 170817
[Lr] Last revision date:170817
[Js] Journal subset:IM
[Da] Date of entry for processing:160504
[St] Status:MEDLINE
[do] DOI:10.5543/tkda.2015.94587

  8 / 205 MEDLINE  
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[PMID]: 27046368
[Au] Autor:Ghahramani GK; Seline AE; Wanat KA
[Ad] Address:Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City.
[Ti] Title:Postprocedural Blue Toes.
[So] Source:JAMA;315(13):1396-7, 2016 Apr 05.
[Is] ISSN:1538-3598
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Coronary Artery Bypass/adverse effects
Embolism, Cholesterol/complications
Hand
Pigmentation Disorders/etiology
Toes
[Mh] MeSH terms secundary: Aged
Coronary Angiography
Embolism, Cholesterol/diagnosis
Humans
Male
Myocardial Infarction/surgery
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1604
[Cu] Class update date: 161017
[Lr] Last revision date:161017
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:160406
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2016.1810

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[PMID]: 26945870
[Au] Autor:Shigyo H; Kawarada O; Noguchi T; Ogawa H; Yasuda S
[Ad] Address:Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.
[Ti] Title:Axillo-femoral bypass steal due to subclavian artery stenosis.
[So] Source:Heart Vessels;31(11):1886-1888, 2016 Nov.
[Is] ISSN:1615-2573
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Subclavian artery stenosis can cause a flow reversal-so-called steal-not only in the ipsilateral vertebral artery, but also in the internal mammary artery in patients with a history of coronary-artery bypass grafting. Subclavian artery stenosis is also associated with peripheral artery disease elsewhere. We report a novel finding of axillo-femoral bypass steal due to subclavian artery stenosis identified by vascular ultrasonography.
[Mh] MeSH terms primary: Axillary Artery/surgery
Blue Toe Syndrome/etiology
Femoral Artery/surgery
Vascular Grafting/adverse effects
[Mh] MeSH terms secundary: Aged, 80 and over
Axillary Artery/diagnostic imaging
Axillary Artery/physiopathology
Blue Toe Syndrome/diagnostic imaging
Blue Toe Syndrome/drug therapy
Blue Toe Syndrome/physiopathology
Femoral Artery/diagnostic imaging
Femoral Artery/physiopathology
Humans
Male
Regional Blood Flow
Subclavian Steal Syndrome/diagnostic imaging
Subclavian Steal Syndrome/drug therapy
Subclavian Steal Syndrome/etiology
Subclavian Steal Syndrome/physiopathology
Treatment Outcome
Ultrasonography, Interventional
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1704
[Cu] Class update date: 171010
[Lr] Last revision date:171010
[Js] Journal subset:IM
[Da] Date of entry for processing:160307
[St] Status:MEDLINE

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[PMID]: 26771983
[Au] Autor:Malecki R; Kluz J; Przezdziecka-Dolyk J; Adamiec R
[Ad] Address:Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University, Poland.
[Ti] Title:The Pathogenesis and Diagnosis of Thromboangiitis obliterans: Is It Still a Mystery?
[So] Source:Adv Clin Exp Med;24(6):1085-97, 2015 Nov-Dec.
[Is] ISSN:1899-5276
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Thromboangiitis obliterans (TAO) is a rare disease of unknown etiology that results in the occlusion of limb arteries located distally to the elbow and knee. Despite the fact that more than one hundred years have passed since its first description, knowledge on the pathogenesis of TAO and precipitating factors is still limited. Due to a lack of decisive noninvasive diagnostic methods and geographical differences in the prevalence of this condition, data on TAO epidemiology also remains sparse. This review presents important evidence on the pathogenesis and the course of the condition, as well as diagnostic modalities, with a focus on differential diagnosis. Theories on the pathogenesis of TAO include the theory of an infectious disease, coagulation disorders and injury to vascular endothelium resulting in activation of the inflammatory response. Differential diagnosis should exclude thoracic outlet syndrome, blue toe syndrome, infectious endocarditis, popliteal entrapment syndrome, Takayasu disease, primary and secondary systemic vasculitis, antiphospholipid syndrome, infection with the anaerobic Clostridium sp. bacilli and some less common conditions.
[Mh] MeSH terms primary: Thromboangiitis Obliterans/diagnosis
Thromboangiitis Obliterans/epidemiology
[Mh] MeSH terms secundary: Adult
Aged
Diagnosis, Differential
Female
Humans
Incidence
Male
Middle Aged
Predictive Value of Tests
Prevalence
Prognosis
Risk Factors
Thromboangiitis Obliterans/therapy
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1603
[Cu] Class update date: 160116
[Lr] Last revision date:160116
[Js] Journal subset:IM
[Da] Date of entry for processing:160116
[St] Status:MEDLINE
[do] DOI:10.17219/acem/33322


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