Database : MEDLINE
Search on : Common and Bile and Duct and Diseases [Words]
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[PMID]: 29320821
[Au] Autor:Choi JH; Seo M
[Ad] Address:Division of Gastroenterology, Department of Internal Medicine, Dankook University College of Medicine, Dankook University Hospital, Cheonan 31116, Korea.
[Ti] Title:A Case of Biliary Ascariasis in Korea.
[So] Source:Korean J Parasitol;55(6):659-660, 2017 Dec.
[Is] ISSN:1738-0006
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:Biliary ascariasis is still the leading cause of surgical complication of ascariasis, though its incidence has been dramatically reduced. Herein, we report a case of biliary ascariasis for the purpose of enhancing awareness of parasitic infections as a possible cause. A 72-year-old male visited the emergency room of Dankook University Hospital on 12 July 2015, complaining of right-upper-quadrant pain. By endoscopic retrograde cholangiopancreatography (ERCP), a tubular filling defect in the right hepatic duct was detected. The defect was endoscopically removed and diagnosed as an adult female of Ascaris lumbricoides worm, of 30 cm length. Upon removal of the worm, the pain subsided, and the patient was discharged without any complication. When treating cases of biliary colic, physicians should not neglect biliary ascariasis as the possible cause.
[Mh] MeSH terms primary: Ascariasis/parasitology
Ascariasis/surgery
Ascaris lumbricoides/isolation & purification
Bile Duct Diseases/parasitology
Bile Duct Diseases/surgery
[Mh] MeSH terms secundary: Abdominal Pain/etiology
Aged
Animals
Ascariasis/complications
Ascariasis/diagnostic imaging
Bile Duct Diseases/complications
Bile Duct Diseases/diagnostic imaging
Cholangiopancreatography, Endoscopic Retrograde
Hepatic Duct, Common/diagnostic imaging
Hepatic Duct, Common/parasitology
Hepatic Duct, Common/surgery
Humans
Male
Republic of Korea
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180112
[St] Status:MEDLINE
[do] DOI:10.3347/kjp.2017.55.6.659

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[PMID]: 29392752
[Au] Autor:Sasaki M; Kuo FY; Huang CC; Swanson PE; Chen CL; Chuang JH; Yeh MM
[Ad] Address:Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
[Ti] Title:Increased expression of senescence-associated cell cycle regulators in the progression of biliary atresia: an immunohistochemical study.
[So] Source:Histopathology;, 2018 Feb 02.
[Is] ISSN:1365-2559
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:AIMS: Cellular senescence plays a role in tumour suppression and in the pathogenesis of various non-neoplastic diseases, including primary biliary cholangitis and other adult cholangiopathies. Less is known about the role of cellular senescence in cholangiopathies in children. With that in mind, we examined the expression of senescence-associated cell cycle regulators in biliary atresia, the most common form of paediatric obliterative cholangiopathy. METHODS AND RESULTS: The expression of senescence-associated cell cycle regulators (p16 and p21 ) and a ductular reaction related marker (neural cell adhesion molecule: NCAM) was examined in bile ducts and bile ductules in liver samples taken from the patients with biliary atresia [n = 80; including 23 samples at the time of the Kasai procedure (KP) and 63 obtained from the explanted liver (LT) (six cases with samples at both surgical stages of disease)] and from appropriate controls (n = 17). The degree of ductular reaction and cholestasis was significantly more extensive in LT than KP (P < 0.01). The expression of p16 and NCAM was significantly more extensive in bile ducts and bile ductules in ductular reaction in both KP and LT compared to controls and in LT compared to KP (P < 0.05). The expression of p21 was significantly more extensive in bile ducts and bile ductules in KP compared to both LT and controls (P < 0.01). CONCLUSIONS: Cellular senescence may play a role in the progression of bile duct loss in biliary atresia in a manner similar to that of adult cholangiopathies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1111/his.13476

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[PMID]: 29504276
[Au] Autor:Tummidi S; Kothari K; Sathe P; Agnihotri M; Fernandes G; Naik L; Jain A; Chaturvedi R
[Ad] Address:Department of Pathology, Seth GSMC & KEMH, Parel, Mumbai 400012, Maharashtra, India.
[Ti] Title:Endoscopic ultrasound guided brush/fine-needle aspiration cytology: A 15-month study.
[So] Source:Diagn Cytopathol;, 2018 Mar 05.
[Is] ISSN:1097-0339
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri-gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS. AIMS AND OBJECTIVE: To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS-FNAC/brush cytology of gastrointestinal and peri-gastrointestinal lesions. MATERIALS AND METHODS: Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done. RESULTS: A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow-up was available in 102 cases with cyto-histopathological concordance rate of 90%. CONCLUSION: EUS-FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre-operative procedure for the management of many intra-abdominal lesions and prevent unnecessary invasive procedures.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[St] Status:Publisher
[do] DOI:10.1002/dc.23917

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[PMID]: 29465584
[Au] Autor:Fan X; He L; Khadaroo PA; Zhou D; Lin H
[Ad] Address:Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine.
[Ti] Title:Duplication of the extrahepatic bile duct: A case report and review of the literatures.
[So] Source:Medicine (Baltimore);97(8):e9953, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Duplication of the extrahepatic bile duct is an extremely rare congenital anomaly of the biliary system. PATIENT CONCERNS: A 44-year-old woman presented with a history of continuous upper abdominal pain and vomiting. DIAGNOSES: Magnetic resonance cholangiopancreatography (MRCP) disclosed diffuse dilatation of the intrahepatic and extrahepatic bile ducts. Endoscopic retrograde cholangiopancreatography (ERCP) showed the presence of two extrahepatic bile ducts with calculus at the distal end of the CBD. INTERVENTIONS: Laparoscopic cholecystectomy (LC) was performed after an ERCP. Choledochoscopy, performed during the operation, showed duplicated common bile duct and the cystic duct was seen opening at the right side of the extrahepatic duct. OUTCOMES: The patient was doing well after 6 months of follow-up. LESSONS: We reported a case of a double common duct with choledocholithiasis and gallstone. This rare anomaly may lead to cholangitis, common bile duct injury during surgery, malignancy occurrence, and should be treated with extreme care.
[Mh] MeSH terms primary: Bile Duct Diseases/congenital
Bile Ducts, Extrahepatic/abnormalities
Common Bile Duct/abnormalities
[Mh] MeSH terms secundary: Adult
Cholangiopancreatography, Endoscopic Retrograde
Cholangiopancreatography, Magnetic Resonance
Cholecystectomy, Laparoscopic
Choledocholithiasis/congenital
Female
Gallstones/congenital
Humans
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009953

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[PMID]: 29465558
[Au] Autor:Xiao J; Xu P; Li B; Hong T; Liu W; He X; Zheng C; Zhao Y
[Ad] Address:Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
[Ti] Title:Analysis of clinical characteristics and treatment of immunoglobulin G4-associated cholangitis: A retrospective cohort study of 39 IAC patients.
[So] Source:Medicine (Baltimore);97(8):e9767, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Immunoglobulin (Ig)G4-associated cholangitis (IAC) is one of the common organ manifestations of IgG4-related systemic disease (ISD). IAC and autoimmune pancreatitis (AIP) may mimic sclerosing cholangitis, cholangiocarcinoma, or pancreatic carcinoma. Diagnosis is based on a combination of clinical, biochemical, radiological, and histological findings.To study the clinical presentation of and treatment strategy for IAC, we reviewed clinical, serologic, and imaging characteristics, as well as treatment response, in 39 patients with IAC. The majority of patients were men (82%). Clinical features on presentation included obstructive jaundice in 26 patients (67%) and abdominal pain in 20 (51%). Positive IgG4 immunostaining was seen in 27 patients. The median serum IgG4 level before treatment was 769.4 mg/dL (range, 309.1-1229.7 mg/dL). After the steroid therapy, the median serum IgG4 level in 23 patients was 247.0 mg/dL (range, 139.0-355.0 mg/dL). Cholangiograms were available in 36 (92%) patients. Stenosis of the lower part of the common bile duct was found in 26 of 39 patients. Stenosis was diffusely distributed in the intra- and extrahepatic bile ducts in 14 of 39 patients. Additionally, strictures of the bile duct were detected in the hilar hepatic lesions in 27 of 39 patients. AIP was the most frequent comorbidity (35/39 in this study) of IAC. Other affected organs included eyes (n = 6), salivary glands (sialadenitis, n = 10), lymph nodes (mediastinal and axillary, n = 3), kidneys (n = 2), and the retroperitoneum (retroperitoneal fibrosis, n = 2).Regarding treatment, 29 patients were treated with steroids, of whom one underwent pancreatoduodenectomy, and one underwent choledochojejunostomy. Eight patients were treated with biliary stents. The remaining 19 patients took prednisolone alone. Eight patients achieved spontaneous resolution. Four patients with suspected pancreatic cancer or cholangiocarcinoma underwent surgery, including 2 patients who also received postoperative steroids. All patients were regularly followed up for 9 to 36 months. Only 2 patients in the steroids treatment group relapsed to manifest obstructive jaundice and high serum IgG4 levels. These 2 patients were treated with steroids and biliary stents, resulting in complete remission.We also review the diagnostic and therapeutic management and discuss recent pathophysiological findings, which might aid in understanding the molecular mechanisms contributing to IAC and other manifestations of IgG4-related diseases (IgG4-RD). Biomarkers that are more accurate are needed to correctly diagnose IAC and prevent misdiagnoses and unnecessary therapeutic interventions.
[Mh] MeSH terms primary: Autoimmune Diseases/immunology
Autoimmune Diseases/therapy
Cholangitis/immunology
Cholangitis/therapy
Immunoglobulin G/blood
[Mh] MeSH terms secundary: Adult
Anti-Inflammatory Agents/therapeutic use
Autoimmune Diseases/pathology
Biliary Tract Surgical Procedures/instrumentation
Biliary Tract Surgical Procedures/methods
Cholangitis/pathology
Choledochostomy
Common Bile Duct/pathology
Constriction, Pathologic
Female
Humans
Male
Middle Aged
Pancreaticoduodenectomy
Pancreatitis/immunology
Prednisolone/therapeutic use
Retrospective Studies
Stents
[Pt] Publication type:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Inflammatory Agents); 0 (Immunoglobulin G); 9PHQ9Y1OLM (Prednisolone)
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009767

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[PMID]: 29486538
[Au] Autor:Khalphallah A; Aref NM; Abu-Seida AM; Elmeligy E; Bayoumi SA; Al-Lethie AA; Salman D
[Ad] Address:Division of Internal Medicine, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt.
[Ti] Title:Hepatobiliary diseases in Buffaloes ( ): clinical, laboratory and ultrasonographic findings.
[So] Source:J Vet Sci;, 2018 Feb 27.
[Is] ISSN:1976-555X
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:This study describes the ultrasonographic findings of five hepatobiliary diseases in buffaloes. Fifty buffaloes including; 20 clinically normal and 30 hepatobiliary diseased buffaloes were enrolled in this study. Complete clinical, radiographic and ultrasonographic examinations and laboratory analyses were conducted. RESULTS: Focal parenchymal lesions including liver abscess (N=12) and hepatic cyst (N=6), diffuse parenchymal lesion (hepatobiliary cirrhosis, N=5) and obstruction of hepatobiliary passages including cholestasis (N=4) and hepatocholelithiasis (N=3) were successfully imaged by ultrasound. Hepatic abscess was imaged as hypoechoic to echogenic circumscribed mass, of various diameters, with distinct echogenic capsule. Hepatic cyst was imaged as pear shaped sac with bright echogenic margin, anechoic content and distal acoustic enhancement. In hepatobiliary fibrosis, the liver showed linear bands of increasing echogenicity with less distinct imaging of the portal vasculature. Cholestasis was imaged as dilatation of the gallbladder (GB) with thickening in its wall and homogenous or heterogenous contents. Hepatocholelithiasis was imaged as an echoic structure within the hepatic parenchyma or within and around GB and bile duct with increasing echogenicity of the hepatic parenchyma than normal. Ultrasonography could be used efficiently as a fast noninvasive tool for screening of the common hepatobiliary diseases in buffaloes under field condition.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[St] Status:Publisher

  7 / 11586 MEDLINE  
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[PMID]: 29459779
[Au] Autor:Tan W; He J; Deng J; Yang X; Cui L; Ran R; Du G; Jiang X
[Ad] Address:Department of Biliary surgery, Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai, 200438, China.
[Ti] Title:Small molecule metabolite biomarkers for hepatocellular carcinoma with bile duct tumor thrombus diagnosis.
[So] Source:Sci Rep;8(1):3309, 2018 Feb 19.
[Is] ISSN:2045-2322
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Hepatocellular carcinoma with bile duct tumor thrombus (BDTT) is a malignant disease. The most commonly used diagnosis methods for BDTT are MRCP/ERCP, ultrasonic diagnosis or CT scan. However, BDTT is often misdiagnosed as other bile duct diseases, such as extrahepatic cholangiocarcinoma (EHCC), choledochal cyst (Cyst) and common bile duct stone (Stone). Diagnostic methods, which are more accurate and less destructive, are urgently needed. In this paper, we analyzed the small molecule metabolites in the serum of BDTT, Stone, Cyst and EHCC patients and normal people using untargeted GC-MS, and identified 21 metabolites that show different levels among different samples. Using targeted UHPLC-QQQ-MS analysis, we found that several metabolites are significantly changed. ROC curve analysis revealed two metabolites, L-citrulline and D-aspartic acid, as potential biomarkers that can distinguish BDTT from other bile duct diseases.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[St] Status:In-Data-Review
[do] DOI:10.1038/s41598-018-21595-4

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[PMID]: 29391088
[Au] Autor:Spence LH; Schwartz S; Kaji AH; Plurad D; Kim D
[Ad] Address:Department of Surgery, Harbor UCLA Medical Center, Torrance, California, USA.
[Ti] Title:Concurrent Biliary Disease Increases the Risk for Conversion and Bile Duct Injury in Laparoscopic Cholecystectomy: A Retrospective Analysis at a County Teaching Hospital.
[So] Source:Am Surg;83(10):1024-1028, 2017 Oct 01.
[Is] ISSN:1555-9823
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Biliary tract disease remains a common indication for operative intervention. The incidence of concurrent biliary tract disease (>2 biliary tract disease processes) is unknown and the impact of more than one biliary tract diagnosis on outcomes remains to be defined. The objective of this study was to determine the effect of concurrent biliary tract disease on conversion rate and outcomes after laparoscopic cholecystectomy. A 5-year retrospective analysis of all patients who underwent a laparoscopic cholecystectomy was performed comparing those with a single biliary diagnosis to patients with concurrent biliary tract disease. Variables analyzed were conversion to open cholecystectomy, incidence of bile duct injury, use of endoscopic retrograde cholangiopancreatography and/or intraoperative cholangiogram, length of surgery, and duration of hospitalization. The incidence of concurrent biliary tract disease was 9 per cent and a conversion to open cholecystectomy was performed in 16 per cent of patients. After adjusting for confounding factors, concurrent biliary tract disease was predictive of conversion (odds ratio 1.6, 95% confidence interval 1.1-2.3, P = 0.03) and bile duct injury (odds ratio 2.5, 95% confidence interval 0.8-5, P = 0.01). Concurrent biliary tract disease patients were more likely to undergo intraoperative cholangiogram or endoscopic retrograde cholangiopancreatography, as well as longer operation and length of stay.
[Mh] MeSH terms primary: Bile Ducts/injuries
Biliary Tract Diseases/surgery
Cholecystectomy, Laparoscopic/adverse effects
Conversion to Open Surgery/statistics & numerical data
Intraoperative Complications/etiology
[Mh] MeSH terms secundary: Adult
Aged
Bile Ducts/surgery
Female
Hospitals, County
Hospitals, Teaching
Humans
Incidence
Intraoperative Complications/epidemiology
Logistic Models
Male
Middle Aged
Odds Ratio
Retrospective Studies
Risk Factors
Treatment Outcome
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180214
[Lr] Last revision date:180214
[Js] Journal subset:IM
[Da] Date of entry for processing:180203
[St] Status:MEDLINE

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[PMID]: 29241851
[Au] Autor:Costamagna G
[Ad] Address:Digestive Endoscopy Unit, Fondazione Policlinico A. Gemelli, Universit Cattolica, Rome, Italy; IHU-USIAS University of Strasbourg, Strasbourg, France.
[Ti] Title:Sphincter of Oddi dysfunction: the never-ending story has come to a conclusion.
[So] Source:Gastrointest Endosc;87(1):211-212, 2018 01.
[Is] ISSN:1097-6779
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Sphincter of Oddi Dysfunction
Sphincter of Oddi
[Mh] MeSH terms secundary: Common Bile Duct Diseases
Humans
Manometry
[Pt] Publication type:EDITORIAL; COMMENT
[Em] Entry month:1802
[Cu] Class update date: 180212
[Lr] Last revision date:180212
[Js] Journal subset:IM
[Da] Date of entry for processing:171216
[St] Status:MEDLINE

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[PMID]: 29365300
[Au] Autor:Gupta A; Jain P
[Ad] Address:Max Super Specialty Hospital, Dehradun, India mail.guptaankur@gmail.com.
[Ti] Title:Calcified Spleen and Gallstones.
[So] Source:N Engl J Med;378(4):380, 2018 Jan 25.
[Is] ISSN:1533-4406
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Calcinosis/diagnostic imaging
Gallstones/diagnostic imaging
Splenic Diseases/diagnostic imaging
[Mh] MeSH terms secundary: Adult
Calcinosis/complications
Gallstones/complications
Hepatitis C, Chronic/complications
Humans
Male
Radiography
Spleen/diagnostic imaging
Splenic Diseases/complications
Tomography, X-Ray Computed
beta-Thalassemia/complications
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180208
[Lr] Last revision date:180208
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180125
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1703915


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