Database : MEDLINE
Search on : Conjunctivitis [Words]
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[PMID]: 27178516
[Au] Autor:Compton CJ; Melson AT; Clark JD; Shipchandler TZ; Nunery WR; Lee HB
[Ad] Address:Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky. Electronic address: cjcompton@gmail.com....
[Ti] Title:Combined medial canthopexy and lateral tarsal strip for floppy eyelid syndrome.
[So] Source:Am J Otolaryngol;37(3):240-4, 2016 May-Jun.
[Is] ISSN:1532-818X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: To describe the eyelid condition known as "floppy eyelid syndrome" and to present the results of our experience treating patients with floppy eyelid syndrome. METHODS: A retrospective analysis of 16 patients from 2009 to 2013 who underwent combined medial canthopexy and lateral tarsal strip by two surgeons (HBL and WRN) for the treatment of floppy eyelid syndrome (FES). Age, gender, presence of obstructive sleep apnea (OSA), papillary conjunctivitis, punctate keratopathy and lash ptosis were recorded pre-operatively. Outcomes assessed included improvement in upper eyelid laxity, operative complications, post-operative symptomatic relief and delayed recurrence of FES. RESULTS: A total of 18 procedures (on 36 eyelids) were performed on 16 patients over the 4-year period. All patients (18/18) had relief of symptoms and good functional results, defined as improvement in lid laxity and resolution of symptoms. Average follow up was 124days. 8 of 16 patients (50%) had a pre-existing diagnosis of OSA. The remaining 8 patients were referred for sleep study and 2 were subsequently diagnosed with OSA. Two patients experienced some degree of FES recurrence without return of symptoms. There was one complication reported in which a partial dehiscence of the lateral canthal tendon occurred which did not require operative revision. CONCLUSIONS: Combined medial canthopexy and lateral tarsal strip are a safe and effective technique for the treatment of floppy eyelid syndrome. There is a strong association of FES and OSA and it is important to have any patient diagnosed with FES evaluated for OSA.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review

  2 / 13670 MEDLINE  
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[PMID]: 27173334
[Au] Autor:He S; Li YJ; Chen J
[Ad] Address:Department of Otolaryngology, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
[Ti] Title:Clinical features of allergic rhinitis in children of Shanghai, China.
[So] Source:Genet Mol Res;15(2), 2016.
[Is] ISSN:1676-5680
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:The aims of the current study were to assess the clinical features of allergic rhinitis (AR) in children in Shanghai. Serum-specific IgE (sIgE) tests were performed on samples from patients with AR symptoms from January 2011 to December 2014. A disease-related questionnaire was completed after AR diagnosis. The allergen profile and clinical features of AR were analyzed. In total, 2713 AR patients were enrolled in this study. Dermatophagoides pteronyssinus was found to be the most common offending allergen in the study population. With increasing age, the prevalence of sIgE against inhalant allergens was significantly increased; however, the opposite trend was observed for food allergens. Additionally, the proportion of children with high levels of sIgE against D. pteronyssinus increased with age. Of the AR cases, 8.6% were classified as intermittent mild, 4.2% as persistent mild, 40.5% as intermittent moderate-severe, and 46.7% as persistent moderate-severe. A family history of allergies and a patient history of allergies within 6 months of birth were significantly associated with the duration and severity of AR symptoms. The occurrence of co-morbidities, such as allergic conjunctivitis, cough, and asthma, gradually increased from intermittent mild, persistent mild, and intermittent moderate-severe to persistent moderate-severe. The most frequently used drugs were topical corticosteroids and oral antihistamines, which were used by 86.7 and 79.0% of patients, respectively. These results confirm the adequacy of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines for classifying AR patients, and advance the understanding of clinical features of AR in children in Shanghai, China.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.4238/gmr.15028118

  3 / 13670 MEDLINE  
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[PMID]: 27158557
[Au] Autor:Jimenez Corona ME; De la Garza Barroso AL; Rodriguez Martínez JC; Luna Guzmán NI; Ruiz Matus C; Díaz Quiñonez JA; Lopez Martinez I; Kuri Morales PA
[Ad] Address:General Directorate of Epidemiology, Ministry of Health, Mexico City, Mexico....
[Ti] Title:Clinical and Epidemiological Characterization of Laboratory-Confirmed Autochthonous Cases of Zika Virus Disease in Mexico.
[So] Source:PLoS Curr;8, 2016.
[Is] ISSN:2157-3999
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Since 2014, autochthonous circulation of Zika virus (ZIKV) in the Americas was detected (Easter Island, Chile). In May 2015, Brazil confirmed autochthonous --transmission and in October of that year Colombia reported their first  cases. Now more than 52 countries have reported cases, including Mexico. To deal with this contingency in Mexico, several surveillance systems, in addition to systems for vector-borne diseases were strengthened with the participation of all health institutions. Also, the Ministry of Health defined an Action Plan against ZIKV for the whole country. METHODS: We analyzed 93 autochthonous cases of ZIKV disease identified by Epidemiological Surveillance System for Zika Virus in Mexico. All autochthonous cases confirmed by laboratory since November 25, 2015 to February 19, 2016 were included. A description of clinical and epidemiological characteristics of 93 cases of ZIKV disease are presenting and, we describe the Action Plan against this public health emergency.  RESULTS: The distribution of cases by sex was 61 men and 32 women; mean age was 35 years old (S.D. 15, range 6-90). The main clinical features in the 93 cases were fever (96.6%), rash (93.3%), non-purulent conjunctivitis (88.8%), headache (85.4%), and myalgia (84.3%). No deaths were reported. CONCLUSION: The ZIKV epidemic poses new challenges to public health systems. The information provided for basic, clinical, and epidemiological research, in addition to the data derived from epidemiological surveillance is essential. However, there are still many unanswered questions regarding mechanisms of transmission, complications, and impact of this virus.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Cu] Class update date: 160511
[Lr] Last revision date:160511
[Da] Date of entry for processing:160509
[St] Status:PubMed-not-MEDLINE

  4 / 13670 MEDLINE  
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[PMID]: 25694171
[Au] Autor:Dogru M; Gunay M; Celik G; Aktas A
[Ad] Address:a Department of Pediatric Allergy and Immunology ....
[Ti] Title:Evaluation of the tear film instability in children with allergic diseases.
[So] Source:Cutan Ocul Toxicol;35(1):49-52, 2016 Mar.
[Is] ISSN:1556-9535
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:CONTEXT: The presence of dry eye syndrome (DES) in ocular allergic diseases was evaluated in several studies. Despite this, little exists about the tear film instability in atopic children including patients with allergic rhinitis (AR), allergic conjunctivitis (AC) and asthma. This is a study which presents intriguing findings regarding the relationship of tear film instability with clinical aspects in atopic children. OBJECTIVE: To determine the tear film instability in children with AR, AC and asthma. MATERIALS AND METHODS: One hundred and thirty-five consecutive children with AR, AC and asthma as study group and 45 children without any systemic and ocular abnormality as control group were included in the study. Skin prick tests, measurement of tear film breakup time (TFBUT), serum immunoglobulin E and eosinophil counts were performed in all patients. Also four subgroups of patients were designated as AR group (Group I), AC group (Group II), asthma group (Group III) and control group (Group IV). RESULTS: Socio-demographic characteristics were similar except for family atopy between the groups (p > 0.05). The mean TFBUT was significantly lower in the study group (15.5 ± 4.4 s) than the control group (18.4 ± 2.9 s; p = 0.000). Also, there was no significant differences in the percentage of the patients who has TFBUT<10 s (p = 0.066). In logistic regression analysis, atopy was found to be the determinant of lower TFBUT (OR = 16.33, 95%; CI = 1.17 to 228.05, p = 0.03). CONCLUSION: The presence of tear film instability was higher in children with AC, AR and asthma. This finding should be taken in consideration in atopic children.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.3109/15569527.2015.1010727

  5 / 13670 MEDLINE  
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[PMID]: 26777622
[Au] Autor:Lin TY; Peng TC
[Ad] Address:Department of Ophthalmology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan.
[Ti] Title:Mimicking Picture of Infectious Conjunctivitis.
[So] Source:Am J Med;129(2):e51, 2016 Feb.
[Is] ISSN:1555-7162
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Eye Diseases/diagnosis
Physical Examination
[Mh] MeSH terms secundary: Humans
[Pt] Publication type:COMMENT; LETTER
[Em] Entry month:1605
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:160118
[St] Status:MEDLINE

  6 / 13670 MEDLINE  
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[PMID]: 26169885
[Au] Autor:Narayana S; McGee S
[Ad] Address:Division of Hospital Medicine, Department of Medicine, University of California, San Francisco.
[Ti] Title:Bedside Diagnosis of the 'Red Eye': A Systematic Review.
[So] Source:Am J Med;128(11):1220-1224.e1, 2015 Nov.
[Is] ISSN:1555-7162
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: In patients with red eye, traditional teachings suggest that photophobia, visual blurring, and eye pain indicate serious eye disease; in patients with presumed conjunctivitis, the finding of purulent drainage traditionally indicates a bacterial cause. The accuracy of these teachings is unknown. METHODS: A MEDLINE search was performed to retrieve articles published between 1966 and April 2014 relevant to the bedside diagnosis of serious eye disease and bacterial conjunctivitis. RESULTS: In patients with red eye, the most useful findings indicating serious eye disease are anisocoria (with the smaller pupil in the red eye and difference between pupil diameters >1 mm; likelihood ratio [LR], 6.5; 95% confidence interval [CI], 2.6-16.3) and photophobia, elicited by direct illumination (LR, 8.3; 95% CI, 2.7-25.9), indirect illumination (LR, 28.8; 95% CI, 1.8-459), or near synkinesis test ("finger-to-nose convergence test," LR, 21.4; 95% CI, 12-38.2). In patients with presumed conjunctivitis, complete redness of the conjunctival membrane obscuring tarsal vessels (LR, 4.6; 95% CI, 1.2-17.1), observed purulent discharge (LR, 3.9; 95% CI, 1.7-9.1), and matting of both eyes in the morning (LR, 3.6; 95% CI, 1.9-6.5) increase the probability of a bacterial cause; failure to observe a red eye at 20 feet (LR, 0.2; 95% CI, 0-0.8) and absence of morning gluing of either eye (LR, 0.3; 95% CI, 0.1-0.8) decrease the probability of a bacterial cause. CONCLUSIONS: Several bedside findings accurately distinguish serious from benign eye disease in patients with red eye and, in patients with presumed conjunctivitis, distinguish bacterial from viral or allergic causes.
[Mh] MeSH terms primary: Eye Diseases/diagnosis
Physical Examination
[Mh] MeSH terms secundary: Conjunctivitis/immunology
Conjunctivitis/microbiology
Diagnosis, Differential
Humans
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1602
[Cu] Class update date: 160512
[Lr] Last revision date:160512
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:151027
[St] Status:MEDLINE

  7 / 13670 MEDLINE  
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[PMID]: 26105087
[Au] Autor:Abroug N; Khairallah-Ksiaa I; Kahloun R; Khochtali S; Zaouali S; Khairallah M
[Ad] Address:Department of Ophthalmology, Fattouma Bourguiba University Hospital, 5019, Monastir, Tunisia.
[Ti] Title:Parinaud's oculoglandular syndrome revealing subclinical Rickettsia conorii infection.
[So] Source:Int Ophthalmol;35(5):717-9, 2015 Oct.
[Is] ISSN:1573-2630
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:The purpose of this study was to report a case of Parinaud's oculoglandular syndrome associated with subclinical Rickettsia conorii infection. We report a case of a 66-year-old male patient presented with unilateral persistent granulomatous conjunctivitis in the left eye and an ipsilateral preauricular lymphadenopathy without associated systemic features. Laboratory evaluation showed a positive indirect immunofluorescence antibody test for R. conorii. The patient received a 2-week course of oral doxycycline, with subsequent complete resolution of all his symptoms. Rickettsial disease should be considered in the differential diagnosis of oculoglandular syndrome with or without associated systemic symptoms in any patient living in or returning from a specific endemic area.
[Mh] MeSH terms primary: Boutonneuse Fever/complications
Ocular Motility Disorders/etiology
[Mh] MeSH terms secundary: Aged
Anti-Bacterial Agents/therapeutic use
Humans
Male
Rickettsia conorii/isolation & purification
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Anti-Bacterial Agents)
[Em] Entry month:1605
[Js] Journal subset:IM
[Da] Date of entry for processing:150828
[St] Status:MEDLINE
[do] DOI:10.1007/s10792-015-0094-2

  8 / 13670 MEDLINE  
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[PMID]: 25895947
[Au] Autor:Nesakumar N; Sethuraman S; Krishnan UM; Rayappan JB
[Ad] Address:Nanosensors Lab, SASTRA University, Thanjavur, Tamil Nadu, 613 401, India.
[Ti] Title:Cyclic voltammetric acetylcholinesterase biosensor for the detection of captan in apple samples with the aid of chemometrics.
[So] Source:Anal Bioanal Chem;407(16):4863-8, 2015 Jun.
[Is] ISSN:1618-2650
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:The presence of captan residues in apples shows high toxicity, which often causes eye and skin irritation, dermatitis, conjunctivitis, and vomiting in humans. In this context, an electrochemical biosensor based on acetylcholinesterase (AChE) immobilized on a ZnO nanorod interface has been proposed. In this work, Hill, dose-response, and first-, second-, and third-order polynomial regression models were successfully applied and the prediction ability of these models was tested with the use of current density obtained from the cyclic voltammograms of appropriate captan solutions. The Pt/ZnO/AChE bioelectrode showed a high sensitivity of 0.538 µA cm(-2) µM(-1) in the linear range from 0.05 to 25.0 µM with a limit of detection of 107 nM. The recovery results were observed between 98.4 and 102.4 % from the apple sample. This work provides a new promising tool for the detection of captan in apple samples.
[Mh] MeSH terms primary: Acetylcholinesterase/chemistry
Biosensing Techniques
Captan/analysis
[Mh] MeSH terms secundary: Electrochemical Techniques
Limit of Detection
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:EC 3.1.1.7 (Acetylcholinesterase); EOL5G26Q9F (Captan)
[Em] Entry month:1602
[Cu] Class update date: 160512
[Lr] Last revision date:160512
[Js] Journal subset:IM
[Da] Date of entry for processing:150528
[St] Status:MEDLINE
[do] DOI:10.1007/s00216-015-8687-1

  9 / 13670 MEDLINE  
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[PMID]: 27164623
[Au] Autor:Blanca-Lopez N; Campo P; Salas M; García Rodríguez C; Palomares F; Blanca M; Canto G; Feo Brito F; Rondon C
[Ad] Address:Allergy Service, Infanta Leonor Hospital, Madrid, Spain....
[Ti] Title:Seasonal Local Allergic Rhinitis in Areas With High Concentrations of Grass Pollen.
[So] Source:J Investig Allergol Clin Immunol;26(2):83-91, 2016.
[Is] ISSN:1018-9068
[Cp] Country of publication:Spain
[La] Language:eng
[Ab] Abstract:BACKGROUND: Local allergic rhinitis (LAR) is a phenotype of allergic rhinitis characterized by the presence of a localized immune response in the nasal mucosa of patients with negative skin prick test (SPT) results and undetectable serum specific IgE (sIgE). It unknown whether LAR is limited to areas with low or moderate aeroallergen exposure. OBJECTIVE: To explore the presence of LAR and the clinical and immunological characteristics of this entity in geographic areas with high grass pollen loads. METHODS: A cross-sectional observational study was carried out in 2 hospitals in central Spain (Madrid and Ciudad Real). Sixty-one patients with seasonal rhinitis and negative SPT results and undetectable serum sIgE were evaluated using a clinical questionnaire, determination of serum total IgE, and a nasal allergen provocation test (NAPT) with Phleum species. The response to NAPT was monitored using assessment of nasal symptoms, acoustic rhinometry, and determination of sIgE, tryptase, and eosinophil cationic protein in the nasal cavity. RESULTS: Seasonal LAR was detected in 37 patients (61%) using the techniques described above. Eleven percent of patients with LAR were adolescents or children, and 14% reported onset of rhinitis in childhood. Most patients reported persistent-moderate seasonal nasal symptoms, and 41% reported worsening of the disease during the last 2 years. Conjunctivitis was the most common comorbidity, affecting 95% of cases. CONCLUSIONS: LAR to grass pollen is relevant in patients with seasonal symptoms indicative of allergic rhinitis but with a negative skin test result who live in areas with high allergenic pollen loads. This entity should be included the differential diagnosis of rhinitis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.18176/jiaci.0018

  10 / 13670 MEDLINE  
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[PMID]: 26294761
[Au] Autor:Scherer LD; Finan C; Simancek D; Finkelstein JI; Tarini BA
[Ad] Address:University of Missouri, Columbia, MO, USA....
[Ti] Title:Effect of "Pink Eye" Label on Parents' Intent to Use Antibiotics and Perceived Contagiousness.
[So] Source:Clin Pediatr (Phila);55(6):543-8, 2016 Jun.
[Is] ISSN:1938-2707
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Parents of children who presented for a pediatrics appointment responded to a clinical vignette that described a child with symptoms consistent with acute viral conjunctivitis. In a 2 × 2 randomized survey design, the physician in the vignette either used the term "pink eye" or "eye infection" to describe the symptoms, and either told parents that antibiotics are likely ineffective at treating the symptoms or did not discuss effectiveness. When the symptoms were referred to as "pink eye," parents remained interested in antibiotics, despite being informed about their ineffectiveness. By contrast, when the symptoms were referred to as an "eye infection," information about antibiotic ineffectiveness significantly reduced interest, Mdiff = 1.63, P < .001. Parents who received the "pink eye" label also thought that the symptoms were more contagious and were less likely to believe that their child could go to child care, compared with parents who received the "eye infection" label, Mdiff = 0.37, P = .38.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review
[do] DOI:10.1177/0009922815601983


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