Database : MEDLINE Search on : Conjunctivitis [Words] References found : 12365 [refine] Displaying: 1 .. 10   in format [Detailed]

page 1 of 1237

go to page

1 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23650909 [Au] Autor: Enríquez R; Sirvent AE; Padilla S; Noguera-Pons R; Andrada E; Ardoy F; Millán I; Amorós F [Ad] Address: Nephrology Section, Hospital General de Elche , Elche , Spain. [Ti] Title: Nephrotic Syndrome and AA Amyloidosis Revealing Adult-Onset Cryopyrin-Associated Periodic Syndrome. [So] Source: Ren Fail;35(5):738-41, 2013. [Is] ISSN: 1525-6049 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: Cryopyrin-associated periodic syndrome (CAPS) is due to gain-of-function mutations in the cryopyrin gene, which determines an overactive inflammatory response. AA amyloidosis is a complication of this syndrome. A 53-year-old man was referred to us because of lower limb edema. Past history: at the age of 20, he complained of arthralgia/arthritis and bilateral hypoacusis. At the age of 35, he presented posterior uveitis, several episodes of conjunctivitis, and progressive loss of visual acuity. Laboratory tests disclosed nephrotic syndrome, and renal biopsy showed AA amyloidosis. He was given anakinra with improvement of arthritis. A genetic study revealed the p.D303N mutation in the cryopyrin gene, and he was diagnosed as having AA amyloidosis due to CAPS. Twenty-one months after starting anakinra, the arthritis has disappeared, although nephrotic-range proteinuria persisted. It is important to be aware of cryopyrin-associated periodic syndrome because it can cause irreversible complications, and there is effective therapy. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review [do] DOI: 10.3109/0886022X.2013.790300

2 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23663473 [Au] Autor: Williams DC; Edney G; Maiden B; Smith PK [Ad] Address: Department, Institute, School of Medicine Gold Coast Campus, Griffith University, 16 High Street, Gold Coast 4222, Australia. daniel.c.r.williams@gmail.com. [Ti] Title: Recognition of allergic conjunctivitis in patients with allergic rhinitis. [So] Source: World Allergy Organ J;6(1):4, 2013. [Is] ISSN: 1939-4551 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: AIMS: To identify the incidence of allergic conjunctivitis in patients with allergic rhinitis. METHODS: One hundred and eighty seven consecutive patients with allergic rhinitis (AR) were directly questioned if they have allergic conjunctivitis (AC) and this was clarified using standard screening questions relating to red, itchy and watery eyes recorded through a total ocular symptom score (TOSS). Patients were also asked about further symptoms that may be attributable to AC: eyelid dermatitis, frequent blinking; eye sensitivity and frontal headache from squinting or. blinking. All patients were given a drop of olopatadine hydrochloride 0.1% in each eye to help identify "silent" disease. 20 healthy non-atopic controls were also treated with olopatadine drops and questioned on ocular symptoms. RESULTS: Fifty five percent of patients with AR were identified as having AC by direct questioning and the use of the TOSS questionaire. A further 41% were identifiable by asking additional questions and performing therapeutic challenge with olopadatine. CONCLUSIONS: AC is a frequent comorbid condition occurring in 95% of our patients with AR. Only 55% of patients were able to identify that they had AC based on standard screening questions. Additional specific questioning and a therapeutic challenge in suspected patients can help identify patients who may benefit from treatment of AC. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Da] Date of entry for processing: 130513 [St] Status: PubMed-not-MEDLINE [do] DOI: 10.1186/1939-4551-6-4

3 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23246122 [Au] Autor: Aoki R; Fukuda K; Ogawa M; Ikeno T; Kondo H; Tawara A; Taniguchi H [Ad] Address: Department of Microbiology, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu City, Japan. cocumaro-op-ruu@gf7.so-net.ne.jp [Ti] Title: Identification of causative pathogens in eyes with bacterial conjunctivitis by bacterial cell count and microbiota analysis. [So] Source: Ophthalmology;120(4):668-76, 2013 Apr. [Is] ISSN: 1549-4713 [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: PURPOSE: To determine the causative pathogens in eyes with bacterial conjunctivitis. DESIGN: Evaluation of diagnostic test or technology. PARTICIPANTS: Thirteen eyes diagnosed clinically with bacterial conjunctivitis and 12 eyes with normal conjunctival sac were studied. METHODS: The bacterial cell numbers were counted in the samples stained by ethidium bromide (EtBr). The microbiota was determined by the clone library method using polymerase chain reaction (PCR) amplification of the 16S ribosomal RNA (rRNA) gene with universal primers. In addition, examinations of smears and cultures of samples were performed. MAIN OUTCOME MEASURES: Bacterial cell numbers determined by the EtBr staining method and microbiota analysis based on 16S rRNA gene of samples from eyes with bacterial conjunctivitis. RESULTS: The bacterial cell numbers in the eyes with bacterial conjunctivitis were significantly higher than those in the normal conjunctival sacs. Ten of 13 samples from the eyes with bacterial conjunctivitis had positive PCR results. The remaining 3 samples and all 12 samples from the normal conjunctiva had negative PCR results. In 5 of the 10 PCR-positive samples, the predominant species accounted for 84.5% or more of each clone library. In the remaining 5 samples, the predominant and the second dominant species accounted for 27.4% to 56.3% and 19.0% to 26.8%, respectively, of each clone library. The number of detected species in the clone libraries was between 8 and 20 (average ± standard deviation, 7.5 ± 5.8). Bacteria were detected in 8 of the 10 bacterial conjunctivitis samples and in 5 of the 12 normal samples in the cultures. The number of species detected by cultures was 1 in the eyes with bacterial conjunctivitis and between 1 and 3 (mean ± standard deviation, 1.6 ± 0.9) in the normal conjunctiva. CONCLUSIONS: These results showed that the bacterial cell number in a sample is a good method of determining bacterial conjunctivitis. The microbiota analysis detected a diverse group of microbiota in the eyes with bacterial conjunctivitis and showed that the causative pathogens could be determined based on percentages of bacterial species in the clone libraries. The combination of bacterial cell count and microbiota analysis is a good method for identifying the causative pathogens in cases of monomicrobial and polymicrobial conjunctivitis. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1304 [Js] Journal subset: IM [St] Status: In-Process

4 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23482464 [Au] Autor: Iwamoto S; Asada Y; Ebihara N; Hori K; Okayama Y; Kashiwakura J; Watanabe Y; Kawasaki S; Yokoi N; Inatomi T; Shinomiya K; Murakami A; Matsuda A [Ad] Address: Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan. [Ti] Title: Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells. [So] Source: Invest Ophthalmol Vis Sci;54(4):2465-73, 2013. [Is] ISSN: 1552-5783 [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: PURPOSE: Intraepithelial mast cells are observed in giant papillae tissue samples obtained from patients with atopic keratoconjunctivitis (AKC)/vernal keratoconjunctivitis (VKC). We examined the roles of interaction between the conjunctival epithelial cells and mast cells. METHODS: The interaction between human mast cells and conjunctival epithelial cells (HCjE) was investigated using a coculture model. Protein array analysis, ELISA, and real-time PCR were performed to test the interaction. Tissue samples (n = 6) from giant papillae were resected for therapeutic purposes, and subjected to immunohistological analysis of CCL2 expression. Recombinant CCL2 (10 ng/mL) was reacted with the cultured human mast cells and ultrastructural analysis was performed. A ragweed (RW)-induced mouse experimental allergic conjunctivitis model was used to examine ccl2 mRNA expression and mast cell morphology. RESULTS: Protein array and real-time PCR analyses showed that CCL2 protein/mRNA expression was induced by mast cell-HCjE coculture. Upregulation of CCL2 mRNA was observed in mast cells, whereas in situ CCL2 expression was observed at the conjunctival epithelium of the giant papillae by immunohistochemistry. Ultrastructural analysis showed that recombinant CCL2 treatment induced piecemeal degranulation (PMD) in the mast cells. Ultrastructural analysis of tissues from the giant papillae showed PMD of mast cells within the conjunctival epithelial cells. The RW-induced experimental allergic conjunctivitis model showed increased ccl2 mRNA expression and PMD morphology in the conjunctivae. CONCLUSIONS: Mast cell-conjunctival epithelial cell interaction induces CCL2 expression and subsequent PMD. [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Entry month: 1304 [Js] Journal subset: IM [St] Status: In-Process [do] DOI: 10.1167/iovs.12-10664

5 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23271473 [Au] Autor: Lin MC; Yeh TN [Ad] Address: Clinical Research Center, School of Optometry, University of California, Berkeley, CA 94720-2020, USA. mlin@berkeley.edu [Ti] Title: Mechanical complications induced by silicone hydrogel contact lenses. [So] Source: Eye Contact Lens;39(1):115-24, 2013 Jan. [Is] ISSN: 1542-233X [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: With the introduction of silicone hydrogel (SiHy) lenses over a decade ago, clinicians have seen both improvements and challenges in contact lens (CL) wear. Regardless of lens design or material, the presence of a CL on the ocular surface induces mechanical complications. Although some of these complications have diminished in frequency and severity with newer generations of SiHy lenses, others persist at previously reported levels. The aim of this review is to provide up-to-date information on mucin balls, superior epithelial arcuate lesions, corneal erosions, CL-induced papillary conjunctivitis, conjunctival epithelial flaps, lid wiper epitheliopathy, and meibomian gland dropout. The conclusions in this review should provide a sound basis for identifying the future areas of research to help minimize mechanically driven adverse events during CL wear with SiHy lenses. [Mh] MeSH terms primary: Conjunctival Diseases/etiology Contact Lenses, Extended-Wear/adverse effects Corneal Diseases/etiology Eyelid Diseases/etiology Hydrogels Silicones [Mh] MeSH terms secundary: Humans [Pt] Publication type: JOURNAL ARTICLE; REVIEW [Nm] Name of substance: 0 (Hydrogels); 0 (Silicones) [Em] Entry month: 1305 [Js] Journal subset: IM [Da] Date of entry for processing: 130107 [St] Status: MEDLINE [do] DOI: 10.1097/ICL.0b013e31827c77fd

6 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23528361 [Au] Autor: Nisar A; Malik AH; Zargar MA [Ad] Address: Department of Biochemistry, University of Kashmir, Srinagar, J&K 190006, India. Electronic address: clinicalbiochemalb@gmail.com. [Ti] Title: Atropa acuminata Royle Ex Lindl. blunts production of pro-inflammatory mediators eicosanoids., leukotrienes, cytokines in vitro and in vivo models of acute inflammatory responses. [So] Source: J Ethnopharmacol;147(3):584-94, 2013 Jun 3. [Is] ISSN: 1872-7573 [Cp] Country of publication: Ireland [La] Language: eng [Ab] Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Atropa acuminata Royle Ex Lindl. has been widely used in folk medicine for several inflammatory disorders such as arthritis, asthma, conjunctivitis, encephalitis, pancreatitis, peritonitis, acute infections and neuroinflammatory disorders. AIM OF THE STUDY: Our aim was to evaluate Atropa acuminata for its anti-inflammatory properties and to delineate its possible mechanism of action on the modulation of the inflammatory mediators. MATERIALS AND METHODS: We investigated the inhibitory action of ethanolic extract of Atropa acuminata (AAEE) on production of NO, TNF-α and IL-1ß in lipopolysaccharide (LPS)-stimulated RAW264.7 cells and also assayed it for COX 1/2 and 5-LOX inhibitory activities. Next AAEE was tested in acute inflammatory animal models., carragenean induced rat paw edema, carragenean induce pleurisy in rats and vascular permeability in mice and the effects on NO, PGE2 and LTB4 production in the pleural fluid and paw exudates were evaluated. In addition the effects on leukocyte migration and exudation and vascular permeability were also observed. RESULTS: Our findings summarized novel anti-inflammatory mechanisms for Atropa acuminata based on dual in vitro cyclooxygenase 1/2/ and 5-Lipoxygenase inhibitory activities and also significant downregulation of nitric oxide (NO) and pro-inflammatory cytokin (TNF-α and Il-1 ß) release in LPS-stimulated RAW 246.7 macrophage cell line. In acute inflammatory models in vivo (carragenean induced edema, carragenean induced pleurisy in rats and vascular permeability in mice), AAEE exhibited an extensive diverse mechanism for anti-inflammatory properties. This was indicated on the basis of dose dependent suppression of multi targeted inflammatory mediators., NO, TNF-α and IL-1ß, eicosanoids., PGE2 and leukotrienes., LTB4 along with significantly decreased leucocyte migration, exudation and decreased vascular permeability. These effects were more potent and prolonged than traditional NSAIDS, thereby indicating fewer side effects. AAEE was found to be safe for long term administration, as confirmed by the results of acute toxicity studies and MTT assay. The complex mode of action of the herbs was attributed possibly due to the high polyphenolic, flavanol and flavonoid content present in the extracts as observed by means of quantitative screening for phytochemicals. CONCLUSION: Our study provides scientific evidence to support the traditional anti-inflammatory uses of Atropa acuminata and is probably due to inhibitory effects on multiple inflammatory mediators which indicates a promising potential for the development of a strong anti-inflammatory agent from this plant. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review

7 / 12365

MEDLINE

select to print Photocopy Full text

[PMID]: 23140273 [Au] Autor: Chen MH; Su TP; Chen YS; Hsu JW; Huang KL; Chang WH; Bai YM [Ad] Address: Department of Psychiatry, Taipei Veterans General Hospital, Taipei Department of Psychiatry, College of Medicine, National Yang-Ming University, Taipei, Taiwan. [Ti] Title: Attention deficit hyperactivity disorder, tic disorder, and allergy: is there a link? A nationwide population-based study. [So] Source: J Child Psychol Psychiatry;54(5):545-51, 2013 May. [Is] ISSN: 1469-7610 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: Background: Attention deficit hyperactivity disorder (ADHD) and tic disorder usually co-occur in the same individuals, but the underlying mechanisms remain unclear. Previous evidence has shown that a frequent coexistence of allergic diseases was noted in patients with ADHD or tic disorder. We attempted to investigate the possible link among ADHD, tic disorder, and various allergic diseases. Methods: Utilizing the Taiwan National Health Insurance Research Database from 1996 to 2010, 5,811 patients with ADHD alone, 1,816 patients with tic disorder alone, and 349 patients with dual diagnoses of ADHD and tic disorder were identified and compared with age-/gender-matched controls (1:4) in an investigation of the association among ADHD, tic disorder, and allergic diseases. Results: Patients with dual diagnoses of ADHD and tic disorder had a significantly higher prevalence of allergic diseases and psychiatric comorbidities, including allergic rhinitis (43% vs. 28.4% vs. 33.6% vs. 19.7%, p < 0.001), asthma (27.5% vs. 17.2% vs. 18.2% vs. 11.9%, p < 0.001), atopic dermatitis (10.6% vs. 8.4% vs. 7.0 vs. 5.9%, p < 0.001), allergic conjunctivitis (55.6% vs. 34.7% vs. 43.5% vs. 26.3%, p < 0.001), obsessive compulsive disorder (4.0% vs. 1.3% vs. 2.0% vs. 0.1%, p < 0.001), and anxiety disorder (22.1% vs. 18.0% vs. 6.0% vs. 0.5%, p < 0.001) than the ADHD alone group, the tic alone group, and the control group. Furthermore, ADHD patients with more allergic diseases (≥3 comorbidities: OR: 3.73, 95% CI: 2.65∼5.25; 2 comorbidities: OR: 2.52, 95% CI: 1.82∼3.47; 1 comorbidity: OR: 1.87, 95% CI: 1.41∼2.49) exhibited an increased risk of tic disorder compared with ADHD patients without allergic disease. Conclusion: A significant association among ADHD, tic disorder, and allergic diseases was noted in our study. The results may inspire further studies to clarify the underlying mechanisms and help us understand more about the complex etiology of ADHD, tic disorder, and their co-occurrence. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Js] Journal subset: IM [St] Status: In-Data-Review [do] DOI: 10.1111/jcpp.12018

8 / 12365

MEDLINE

select to print Photocopy PubMed Central Full text Full text

[PMID]: 23650458 [Au] Autor: Schultz C [Ad] Address: Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada. ; Biogram Inc., Ponte Vedra, FL, USA. [Ti] Title: Gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis: safety, efficacy and patient perspective. [So] Source: Ophthalmol Eye Dis;4:65-70, 2012. [Is] ISSN: 1179-1721 [Cp] Country of publication: New Zealand [La] Language: eng [Ab] Abstract: Gatifloxacin is a fourth generation fluroquinolone antibiotic that has been prescribed for systemic use. However, the drug which was developed by Kyorin (Japan) was linked to toxic reactions and death and was banned in the United States and Canada for use as an oral dosage form. It continues to be used as a topical application for ophthalmic conditions as the systemic toxicity seen when taking the drug orally has not been observed with ophthalmic use. The available data indicate that ocular use of gatifloxacin is safe, and effective against a broad spectrum of bacteria, including intracellular bacteria and anaerobes. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Cu] Class update date: 130510 [Lr] Last revision date: 130510 [Da] Date of entry for processing: 130507 [St] Status: PubMed-not-MEDLINE [do] DOI: 10.4137/OED.S7383

9 / 12365

MEDLINE

select to print Photocopy PubMed Central Full text Full text

[PMID]: 23650453 [Au] Autor: Opitz DL; Harthan JS [Ad] Address: Illinois College of Optometry, Department of Clinical Education, 3241 South Michigan Avenue, Chicago, Illinois 60616, USA. [Ti] Title: Review of Azithromycin Ophthalmic 1% Solution (AzaSite(®)) for the Treatment of Ocular Infections. [So] Source: Ophthalmol Eye Dis;4:1-14, 2012. [Is] ISSN: 1179-1721 [Cp] Country of publication: New Zealand [La] Language: eng [Ab] Abstract: AzaSite(®) (azithromomycin 1.0%) ophthalmic solution was approved in 2007 by the US Food and Drug Administration (FDA) as the first commercially available formulation of ophthalmic azithromycin for the treatment of bacterial conjunctivitis. AzaSite(®) utilizes a vehicle delivery system called DuraSite(®), which stabilizes and sustains the release of azithromycin to the ocular surface, leading to a longer drug residence time, less frequent dosing, and an increase in patient compliance. AzaSite(®) is a broad spectrum antibiotic, effective against Gram-positive, Gram-negative, and atypical bacteria. AzaSite(®) has been studied for the treatment of ocular conditions beyond its clinical indication. A number of clinical studies have evaluated its efficacy and safety in the management of ocular conditions such as bacterial conjunctivitis and blepharitis on both the pediatric and adult populations. This article aims to evaluate the peer-reviewed published literature on the use of azithromycin 1.0% ophthalmic for current and possible future ophthalmic uses. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Cu] Class update date: 130510 [Lr] Last revision date: 130510 [Da] Date of entry for processing: 130507 [St] Status: PubMed-not-MEDLINE [do] DOI: 10.4137/OED.S7791

10 / 12365

MEDLINE

select to print Photocopy PubMed Central Full text Full text

[PMID]: 23650456 [Au] Autor: Ovenseri-Ogbomo G; Ocansey S; Abu E; Kyei S; Boadi-Kusi S [Ad] Address: Department of Optometry, University of Cape Coast, Ghana. [Ti] Title: Oculo-Visual Findings among Industrial Mine Workers at Goldfields Ghana Limited, Tarkwa. [So] Source: Ophthalmol Eye Dis;4:35-42, 2012. [Is] ISSN: 1179-1721 [Cp] Country of publication: New Zealand [La] Language: eng [Ab] Abstract: OBJECTIVE: The focus of this study was to evaluate the visual status of mine workers who were directly involved in mining and/or are exposed to the mining environment. METHODS: A hospital based cross-sectional study was conducted. Four hundred and six (406) workers were conveniently sampled for the study. Information on their socio-demographic data was also collected. In addition, all participants underwent ophthalmic examination. RESULTS: The mean age of the workers was 41.1 years. Visual impairment was found in 114 (28.1%) of the study population of which refractive error (56.8%) was the major cause. Presbyopia was also observed in 45.5% of the workers with only 30.3% of them wearing near correction. The prevalence of eye diseases were pterygium/pingueculae (25.8%), conjunctivitis (26.8%), suspected glaucoma (15.3%), and cataract (7.4%). CONCLUSIONS: Visual impairment and eye diseases were found among the miners. [Pt] Publication type: JOURNAL ARTICLE [Em] Entry month: 1305 [Cu] Class update date: 130510 [Lr] Last revision date: 130510 [Da] Date of entry for processing: 130507 [St] Status: PubMed-not-MEDLINE [do] DOI: 10.4137/OED.S9204

---

page 1 of 1237

go to page

Refine the search

Database : MEDLINE

Advanced form

		Search	in field
1			WordsSubject descriptorMajor Subject descriptorLimitsAuthorTitle wordsAbstract wordsLanguageCountry of publicationName of substancePersonal name as subjectJournalJournal DescriptorISSNPublication typeUnique identifierEntry monthYear of PublicationFulltextClass update dateDeCS CategoryDeCS Category explodedICD-10 CategorySubSetsAffiliation CountryAffiliation
2	and or and not		WordsSubject descriptorMajor Subject descriptorLimitsAuthorTitle wordsAbstract wordsLanguageCountry of publicationName of substancePersonal name as subjectJournalJournal DescriptorISSNPublication typeUnique identifierEntry monthYear of PublicationFulltextClass update dateDeCS CategoryDeCS Category explodedICD-10 CategorySubSetsAffiliation CountryAffiliation
3	and or and not		WordsSubject descriptorMajor Subject descriptorLimitsAuthorTitle wordsAbstract wordsLanguageCountry of publicationName of substancePersonal name as subjectJournalJournal DescriptorISSNPublication typeUnique identifierEntry monthYear of PublicationFulltextClass update dateDeCS CategoryDeCS Category explodedICD-10 CategorySubSetsAffiliation CountryAffiliation

Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information