Database : MEDLINE
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[PMID]: 29521364
[Ti] Title:Effectiveness of oral health education on oral hygiene and dental caries in schoolchildren: Systematic review and meta-analysis.
[So] Source:Br Dent J;224(5):357, 2018 Mar 09.
[Is] ISSN:1476-5373
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Analysis of recently published research appears to show only short-term improvements in plaque indices.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review
[do] DOI:10.1038/sj.bdj.2018.195

  2 / 23830 MEDLINE  
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[PMID]: 29520910
[Au] Autor:Kotsakis GA; Lian Q; Ioannou AL; Michalowicz BS; John M; Chu H
[Ad] Address:Department of Periodontics, University of Washington, Seattle, WA.
[Ti] Title:A network meta-analysis of interproximal oral hygiene methods in the reduction of clinical indices of inflammation.
[So] Source:J Periodontol;, 2018 Feb 19.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: A wide selection of Interdental Oral Hygiene (IOH) aids is available to consumers. Recommendations for selection are, however, limited by the lack of direct comparisons in available studies. We aimed to assess the comparative efficacy of IOH aids using Bayesian Network Meta-Analysis (BNMA). METHODS: Two independent reviewers performed a systematic literature review of randomized clinical trials assessing IOH aids, based on a focused question. Gingival inflammation (Gingival Index (GI), Bleeding-on-probing (BOP)) was the primary outcome and plaque and probing depth were secondary outcomes A random-effects arm-based BNMA model was run for each outcome; posterior medians and 95% credible-intervals (CIs) summarized marginal distributions of parameters. RESULTS: A two-phase selection process identified 22 trials assessing 10 IOH aids as brushing adjuncts. Interdental brushes (IB) yielded the largest reduction in GI (0.23 [95% CI: 0.09, 0.37]) as toothbrushing adjuncts, followed by water-jet (WJ) (0.19 [95% CI: 0.14, 0.24]). Rankings based on posterior probabilities revealed that IB and WJ had the highest probability of being "best" (64.7% and 27.4%, respectively) for GI reduction, while the probability for toothpick and floss being the "best" IOH aids was near zero. Notably, except for toothpicks, all IOH aids were better at reducing GI as compared to control. CONCLUSIONS: BNMA enabled us to quantitatively evaluate IOH aids and provide a global ranking of their efficacy. Interdental brushes and water-jets ranked high for reducing gingival bleeding, while toothpicks and floss ranked last. The patient-perceived benefit of IOH aids is not clear because gingival inflammation measures are physical indicators of periodontal health. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1002/JPER.17-0368

  3 / 23830 MEDLINE  
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[PMID]: 29520826
[Au] Autor:Ribeiro FV; Casati MZ; Casarin RC; Corrêa MG; Cirano FR; Negri BM; Pimentel SP
[Ad] Address:Dental Research Division, School of Dentistry, Paulista University, São Paulo, São Paulo, Brazil.
[Ti] Title:Impact of a triclosan-containing toothpaste during the progression of experimental peri-implant mucositis: Clinical parameters and local pattern of osteo-immunoinflammatory mediators in peri-implant fluid.
[So] Source:J Periodontol;89(2):203-212, 2018 Feb.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: This study evaluated the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in peri-implant crevicular fluid (PICF) and in clinical parameters during progression of peri-implant mucositis. METHODS: Twenty-two clinically healthy patients with an implant-supported single-unit crown were enrolled in this double-blind, randomized, crossover study carried out in two phases of 21 days each. During an experimental 3-week period of undisturbed plaque accumulation in the implants, patients were randomly assigned to use three times/day: triclosan (n = 11), triclosan/copolymer/fluoride toothpaste; or placebo (n = 11), fluoride toothpaste. After a professional prophylaxis, a washout period of 30 days was established. Clinical parameters and 15 osteo-immunoinflammatory mediators in the PICF were evaluated at baseline and at 3, 7, 14, and 21 days. RESULTS: Both groups showed increase in plaque index at implant sites from the 3rd until the 21st day (P < 0.05). Only triclosan treatment was able to avoid an increase in bleeding on probing (BOP) throughout the follow-ups (P > 0.05), whereas a significant intensification in BOP was observed from the 14th day in the placebo-treated sites (P < 0.05). Lower interleukin (IL)-10 concentrations were detected in the placebo group at the 21st day when compared with triclosan-treated implant sites (P < 0.05). IL-10 levels were reduced and IL-1ß concentrations were increased at 21 days when compared with baseline only in placebo-treated sites (P < 0.05). Osteoprotegerin levels significantly increased from the 14th until the 21st day only in triclosan-treated sites (P < 0.05). CONCLUSION: Triclosan-containing toothpaste controls clinical inflammation and interferes positively in the profile of osteo-immunoinflammatory mediators during progression of experimental peri-implant mucositis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review
[do] DOI:10.1002/JPER.17-0302

  4 / 23830 MEDLINE  
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[PMID]: 29520806
[Au] Autor:Bassir SH; Chase I; Paster BJ; Gordon LB; Kleinman ME; Kieran MW; Kim DM; Sonis A
[Ad] Address:Division of Periodontology, Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
[Ti] Title:Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome.
[So] Source:J Periodontol;, 2018 Feb 19.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder with significant oral and dental abnormalities. Clinical symptoms include various features of accelerated aging such as alopecia, loss of subcutaneous fat, bone abnormalities, and premature cardiovascular disease. In addition, children with HGPS have been observed to suffer from generalized gingival recession. Whether periodontal manifestations associated with this syndrome are the results of changes in the oral flora is unknown. The present study aimed to identify the microbial composition of subgingival sites with gingival recession in children with HGPS. METHODS: Nine children with HGPS were enrolled in this study. Plaque samples were collected from teeth with gingival recession. DNA samples were analyzed using the Human Oral Microbe Identification Microarray (HOMIM). Microbial profiles from HGPS children were compared with microbial profiles of controls from healthy individuals (n = 9) and subjects with periodontal disease (n = 9). RESULTS: Comparison of microbial compositions of HGPS samples with periodontal health samples demonstrated significant differences for 2 bacterial taxa; Porphyromonas catoniae and Prevotella oulora were present in children with HGPS, but not normal controls. There were statistically significant differences of 20 bacterial taxa between HGPS and periodontal disease groups. CONCLUSION: Typical periodontal pathogeneses were not present at sites with gingival recession in HGPS children. The microbial compositions of sites of gingival recession and attachment loss in HGPS were generally more similar to those of periodontal health than periodontal disease. Species other than typical periodontal pathogens may be involved in this recession. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1002/JPER.17-0351

  5 / 23830 MEDLINE  
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[PMID]: 29520801
[Au] Autor:Al-Sowygh ZH; Al-Kheraif AA; Akram Z; Vohra F; Javed F
[Ad] Address:Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
[Ti] Title:Peri-implant soft tissue inflammatory parameters and crestal bone loss among waterpipe (Narghile) smokers and never-smokers with and without type 2 diabetes mellitus.
[So] Source:J Periodontol;, 2018 Mar 08.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Peri-implant soft tissue inflammatory parameters and crestal bone loss (CBL) among waterpipe smokers (WS) with and without type 2 diabetes mellitus (T2DM) remains uninvestigated. The aim of the present study was to assess peri-implant soft tissue inflammatory parameters and CBL among WS and never smokers (NS) with and without T2DM. METHODS: Demographic data and information regarding duration of implants in function, daily frequency of smoking, duration and treatment of T2DM and daily tooth brushing was collected using a questionnaire. Peri-implant plaque index (PI), bleeding on probing (BOP), probing depth (PD)≥4 mm, CBL and hemoglobin A1c (HbA1c) levels were assessed in all individuals. Level of significance was set at 5%. RESULTS: Seventy-nine male individuals (39 patients with T2DM [20 WS and 19 NS] and 40 systemically healthy individuals [21 WS smokers and 19 NS]) were included. The mean age was comparable among individuals in all groups. The mean HbA1c levels were significantly higher among patients with T2DM compared to controls (P < 0.01). Peri-implant PI, BOP, PD and CBL were comparable among WS and NS with T2DM. Among patients without T2DM, PI (P < 0.05), PD≥4 mm [P < 0.05] and mesial and distal CBL (P < 0.05) were significantly higher in WS than NS. Among individuals without T2DM, BOP was significantly higher among NS (P < 0.05) than WS. In patients with T2DM, BOP was comparable among WS and NS. CONCLUSION: Peri-implant soft tissue inflammatory parameters and CBL were comparable among WS and NS with T2DM. Among individuals without T2DM, these parameters were worse among WS than NS. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1002/JPER.17-0554

  6 / 23830 MEDLINE  
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[PMID]: 29520791
[Au] Autor:Mehmood A; Abduljabbar T; Al-Hamoudi N; Gholamiazizi E; Kellesarian SV; Vohra F; Javed F
[Ad] Address:Department of Dentistry, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
[Ti] Title:Self-perceived oral symptoms and periodontal status among young intravenous heroin addicts: A cross-sectional case-control study.
[So] Source:J Periodontol;, 2018 Feb 19.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: It is hypothesized that (a) self-perceived oral symptoms (OSs) are worse in intravenous heroin addicts (IHA) than controls; and (b) clinical periodontal inflammatory parameters (plaque index [PI], bleeding on probing [BOP], PD and clinical attachment loss [AL]), number of missing teeth (MT) and radiographic marginal bone loss (MBL) are higher in IHA compared with controls. The aim was to compare the self-perceived OSs and periodontal parameters among young IHA and controls. METHODS: Sociodemographic data, self-perceived OSs and duration and daily frequency of intravenous heroin use was gathered using a structured questionnaire. Full-mouth PI, BOP, PD and clinical AL were measured and number of MT were recorded. Mesial and distal MBL on all teeth was measured on digital radiographs. Odds ratios (OR) with 95% confidence intervals (CI) were computed for self-perceived OSs and periodontal parameters were assessed using the Mann Whitney U-test and logistic regression analysis. Sample-size was estimated and level of significance was set at P < 0.05. RESULTS: OR (95% CI) for self-perceived loose teeth (P < 0.001), pain in teeth (P < 0.001), dry mouth (P < 0.001), burning sensation in mouth (P < 0.001), bleeding gums (P < 0.001) and pain during chewing (P < 0.001) were significantly higher in the test than control-group. Number of MT (P < 0.05), PI (P < 0.05), clinical AL (P < 0.05) and mesial (P < 0.05) and distal (P < 0.05) MBL were statistically significantly higher among individuals in the test-group compared with the control-group. CONCLUSION: Self-perceived OSs and periodontal inflammatory parameters were worse in IHA than controls. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1002/JPER.17-0495

  7 / 23830 MEDLINE  
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SciELO Brazil full text

[PMID]: 29489935
[Au] Autor:Zhang W; Deng X; Zhou X; Hao Y; Li Y
[Ad] Address:State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, People's Republic of China.
[Ti] Title:Influence of Helicobacter pylori culture supernatant on the ecological balance of a dual-species oral biofilm.
[So] Source:J Appl Oral Sci;26:e20170113, 2018.
[Is] ISSN:1678-7765
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Dental caries is a chronic progressive disease occurring in the tooth hard tissue due to multiple factors, in which bacteria are the initial cause. Both Streptococcus mutans and Streptococcus sanguinis are main members of oral biofilm. Helicobacter pylori may also be detected in dental plaque, playing an important role in the development of dental caries. OBJECTIVE: The aim of this study was to investigate the effect of H. pylori culture supernatant on S. mutans and S. sanguinis dual-species biofilm and to evaluate its potential ability on affecting dental health. MATERIAL AND METHODS: The effect of H. pylori supernatant on single-species and dual-species biofilm was measured by colony forming units counting and fluorescence in situ hybridization (FISH) assay, respectively. The effect of H. pylori supernatant on S. mutans and S. sanguinis extracellular polysaccharides (EPS) production was measured by both confocal laser scanning microscopy observation and anthrone-sulfuric acid method. The effect of H. pylori supernatant on S. mutans gene expression was measured by quantitative real-time PCR (qRT-PCR) assays. RESULTS: H. pylori supernatant could inhibit both S. mutans and S. sanguinis biofilm formation and EPS production. S. sanguinis inhibition rate was significantly higher than that of S. mutans. Finally, S. mutans bacteriocin and acidogenicity related genes expression were affected by H. pylori culture supernatant. CONCLUSION: Our results showed that H. pylori could destroy the balance between S. mutans and S. sanguinis in oral biofilm, creating an advantageous environment for S. mutans, which became the dominant bacteria, promoting the formation and development of dental caries.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process

  8 / 23830 MEDLINE  
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[PMID]: 28743239
[Au] Autor:Senneby A; Davies JR; Svensäter G; Neilands J
[Ad] Address:Department of Oral and Maxillofacial Radiology, Malmö University, Faculty of Odontology, 205 06, Malmö, SE, Sweden.
[Ti] Title:Acid tolerance properties of dental biofilms in vivo.
[So] Source:BMC Microbiol;17(1):165, 2017 Jul 25.
[Is] ISSN:1471-2180
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: The ecological plaque hypothesis explains caries development as the result of the enrichment of acid tolerant bacteria in dental biofilms in response to prolonged periods of low pH. Acid production by an acid tolerant microflora causes demineralisation of tooth enamel and thus, individuals with a greater proportion of acid tolerant bacteria would be expected to be more prone to caries development. Biofilm acid tolerance could therefore be a possible biomarker for caries prediction. However, little is known about the stability of biofilm acid tolerance over time in vivo or the distribution throughout the oral cavity. Therefore the aim of this study was to assess intra-individual differences in biofilm acid-tolerance between different tooth surfaces and inter-individual variation as well as stability of acid tolerance over time. RESULTS: The majority of the adolescents showed low scores for biofilm acid tolerance. In 14 of 20 individuals no differences were seen between the three tooth sites examined. In the remaining six, acid-tolerance at the premolar site differed from one of the other sites. At 51 of 60 tooth sites, acid-tolerance at baseline was unchanged after 1 month. However, acid tolerance values changed over a 1-year period in 50% of the individuals. CONCLUSIONS: Biofilm acid tolerance showed short-term stability and low variation between different sites in the same individual suggesting that the acid tolerance could be a promising biological biomarker candidate for caries prediction. Further evaluation is however needed and prospective clinical trials are called for to evaluate the diagnostic accuracy.
[Mh] MeSH terms primary: Acids/pharmacology
Biofilms/drug effects
Dental Plaque/microbiology
[Mh] MeSH terms secundary: Adolescent
Bacteria/classification
Bacteria/isolation & purification
Bacterial Physiological Phenomena/drug effects
Child
Female
Humans
Male
Mouth/microbiology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Acids)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:170727
[St] Status:MEDLINE
[do] DOI:10.1186/s12866-017-1074-7

  9 / 23830 MEDLINE  
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SciELO Brazil full text

[PMID]: 29364329
[Au] Autor:Musskopf ML; Milanesi FC; Rocha JMD; Fiorini T; Moreira CHC; Susin C; Rösing CK; Weidlich P; Oppermann RV
[Ad] Address:Department of Periodontology, Faculty of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
[Ti] Title:Oral health related quality of life among pregnant women: a randomized controlled trial.
[So] Source:Braz Oral Res;32:e002, 2018.
[Is] ISSN:1807-3107
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:The aim of the present study was to compare negative impacts of oral conditions in Oral Heath Related Quality of Life (OHRQoL) assessed by the Oral Health Impact Profile-14 (OHIP-14) scores in pregnant women receiving or not comprehensive periodontal treatment. This randomized controlled clinical trial included pregnant women aged between 18 and 35 years old. Participants were randomized in a test group with 96 and a control group with 114 women. Patients in the test group received comprehensive periodontal treatment, supra and subgingival scaling and root-planning and periodontal maintenance appointments. The OHIP-14 was applied before and after treatment. The primary outcome was changes in OHIP-14 scores after follow-up period. The impact of having received or not comprehensive periodontal treatment on the change of the OHIP-14 scores was also investigated. Both groups showed significant reduction in OHIP-14 scores and effect size for the test group was 0.60 and 0.36 for the control group. Multinomial logistic regression analysis showed that participants of the control group had 5.9-fold odds (CI 95% 1.88-18.52) of worsening in OHIP-14 scores and their perception of oral conditions in relation to test group. Comprehensive periodontal treatment during pregnancy can reduce the negative impacts in OHRQoL.
[Mh] MeSH terms primary: Oral Health/statistics & numerical data
Periodontal Diseases/therapy
Pregnancy Complications/therapy
Quality of Life
[Mh] MeSH terms secundary: Adult
Dental Plaque Index
Female
Health Status
Humans
Logistic Models
Periodontal Index
Pregnancy
Prenatal Care
Sickness Impact Profile
Socioeconomic Factors
Surveys and Questionnaires
Treatment Outcome
Young Adult
[Pt] Publication type:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[Js] Journal subset:D; IM
[Da] Date of entry for processing:180125
[St] Status:MEDLINE

  10 / 23830 MEDLINE  
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[PMID]: 29512317
[Au] Autor:Elkerbout TA; Slot DE; Van Loveren C; Van der Weijden GA
[Ad] Address:Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
[Ti] Title:Will a chlorhexidine-fluoride mouthwash reduce plaque and gingivitis?
[So] Source:Int J Dent Hyg;, 2018 Mar 07.
[Is] ISSN:1601-5037
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:FOCUS QUESTION: What is the efficacy of a chlorhexidine (CHX) mouthwash (MW) containing sodium fluoride (NaF) compared to a CHX - MW alone on the parameters of plaque, gingivitis and discoloration? MATERIAL AND METHODS: MEDLINE-PubMed, Cochrane-CENTRAL, and EMBASE were searched for papers from inception to December 2017. The inclusion criteria were (randomized) controlled clinical trials conducted in human subjects with good general health and without removable prosthesis. Papers evaluating the effect of a MW containing CHX + NaF compared to a CHX alone were included. From the eligible studies, data were extracted, a descriptive analysis was performed and a meta-analysis when feasible. RESULTS: Independent screening of 412 unique papers resulted in 9 eligible publications presenting 10 clinical trials comparing the effect of CHX + NaF to CHX - MW and provided 13 comparisons. Five evaluated the MW as an adjunct to brushing and 8 were non-brushing comparisons of which 4 used an experimental gingivitis model. No significant difference was observed for plaque score reduction in the brushing studies the end scores (diffM; -0.04, P = .36; 95%CI: [-0.13, 0.05]) nor the differences (diffM; 0.11, P = .33; 95%CI: [-0.12, 0.24]). In the descriptive analysis, none of the experiments demonstrated a statistical significant difference regarding Gingival Index (GI), Bleeding Score and Discoloration Scores. For the GI, a meta-analysis of the difference of Means was not significant when included experimental gingivitis model studies end scores (0.01, P = .78; 95%CI: [-0.08, 0.11]) and the difference (0.01, P = .81; 9 5%CI: [-0.08, 0.10]) either for the end scores of brushing studies (diffM; -0.01, P = .82; 95%CI: [-0.10, 0.08]). CONCLUSION: From this study, it can be concluded that NaF and CHX may be present in the same MW without reducing CHX efficacy with respect to plaque and gingivitis scores. Moreover, no difference in the development of tooth discoloration was observed.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:Publisher
[do] DOI:10.1111/idh.12329


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