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[PMID]: 25791400
[Au] Autor:van Hinsbergen DJ; Abels HA; Bosch W; Boekhout F; Kitchka A; Hamers M; van der Meer DG; Geluk M; Stephenson RA
[Ad] Address:Department of Earth Sciences, University of Utrecht, Budapestlaan 4, 3584 CD Utrecht, the Netherlands....
[Ti] Title:Sedimentary geology of the middle Carboniferous of the Donbas region (Dniepr-Donets basin, Ukraine).
[So] Source:Sci Rep;5:9099, 2015.
[Is] ISSN:2045-2322
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The Paleozoic Dniepr-Donets Basin in Belarus, Ukraine, and Russia forms a major hydrocarbon province. Although well- and seismic data have established a 20 km thick stratigraphy, field-studies of its sediments are scarce. The inverted Donbas segment (Ukraine) exposes the middle Carboniferous part of the basin's stratigraphy. Here, we provide detailed sedimentological data from 13 sections that cover 1.5 of the total of 5 km of the Bashkirian and Moscovian stages and assess the paleoenvironment and paleo-current directions. Middle Carboniferous deposition occurred in a shelf environment, with coal deposition, subordinate fluvial facies, and abundant lower and middle shoreface facies, comprising an intercalated package of potential source and reservoir rocks. Sedimentary facies indicate a paleodepth range from below storm wave base to near-coastal swamp environments. Sedimentation and subsidence were hence in pace, with subtle facies changes likely representing relative sea-level changes. Paleocurrent directions are remarkably consistently southeastward in time and space in the different sedimentary facies across the Donbas Fold Belt, illustrating a dominant sedimentary infill along the basin axis, with little basin margin influence. This suggests that the middle Carboniferous stratigraphy of the Dniepr-Donets basin to the northwest probably contains significant amounts of fluvial sandstones, important for assessing hydrocarbon reservoir potential.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1038/srep09099

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[PMID]: 25790333
[Au] Autor:Bo M; Bavestrello G; Angiolillo M; Calcagnile L; Canese S; Cannas R; Cau A; D'Elia M; D'Oriano F; Follesa MC; Quarta G; Cau A
[Ad] Address:Università degli Studi di Genova, Dipartimento di Scienze della Terra, dell'Ambiente e della Vita, Genova, Italy....
[Ti] Title:Persistence of Pristine Deep-Sea Coral Gardens in the Mediterranean Sea (SW Sardinia).
[So] Source:PLoS One;10(3):e0119393, 2015.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Leiopathes glaberrima is a tall arborescent black coral species structuring important facies of the deep-sea rocky bottoms of the Mediterranean Sea that are severely stifled by fishing activities. At present, however, no morphological in vivo description, ecological characterization, age dating and evaluation of the possible conservation actions have ever been made for any population of this species in the basin. A dense coral population was reported during two Remotely Operated Vehicle (ROV) surveys conducted on a rocky bank off the SW coasts of Sardinia (Western Mediterranean Sea). L. glaberrima forms up to 2 m-tall colonies with a maximal observed basal diameter of nearly 7 cm. The radiocarbon dating carried out on a colony from this site with a 4 cm basal diameter revealed an approximately age of 2000 years. Considering the size-frequency distribution of the colonies in the area it is possible to hypothesize the existence of other millennial specimens occupying a supposedly very stable ecosystem. The persistence of this ecosystem is likely guaranteed by the heterogeneous rocky substrate hosting the black coral population that represents a physical barrier against the mechanical impacts acted on the surrounding muddy areas, heavily exploited as trawling fishing grounds. This favorable condition, together with the existence of a nursery area for catsharks within the coral ramifications and the occurrence of a meadow of the now rare soft bottom alcyonacean Isidella elongata in small surviving muddy enclaves, indicates that this ecosystem have to be considered a pristine Mediterranean deep-sea coral sanctuary that would deserve special protection.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1371/journal.pone.0119393

  3 / 5513 MEDLINE  
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[PMID]: 25348364
[Au] Autor:Marchina C; Bianchini G; Natali C; Pennisi M; Colombani N; Tassinari R; Knoeller K
[Ad] Address:Dipartimento di Fisica e Scienze della Terra, Università di Ferrara, Ferrara, Italy.
[Ti] Title:The Po river water from the Alps to the Adriatic Sea (Italy): new insights from geochemical and isotopic (δ(18)O-δD) data.
[So] Source:Environ Sci Pollut Res Int;22(7):5184-203, 2015 Apr.
[Is] ISSN:1614-7499
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Although the Po river is the most important fluvial system of Northern Italy, the systematic geochemical and isotopic investigations of its water are rare and were never reported for the whole basin. The present contribution aims to fill this knowledge gap, reporting a comprehensive data set including oxygen and hydrogen stable isotopes as well as major and trace element concentration of dissolved species for 54 Po river water samples, mainly collected in different hydrological conditions (peak discharge in April, drought in August) at increasing distance from the source, i.e., from the upper part of the catchment to the terminal (deltaic) part of the river at the confluence with the Adriatic Sea. The isotopic compositions demonstrate that the predominant part of the runoff derives from the Alpine sector of the catchment through important tributaries such as the Dora Baltea, Ticino, Adda, and Tanaro rivers, whereas the contribution from the Apennines tributaries is less important. The geochemical and isotopic compositions show that the Po river water attains a homogeneous composition at ca. 100 km from the source. The average composition is characterized by δ(18)O -9.8 ‰, δD -66.2 ‰, total dissolved solid (TDS) 268 mg/L, and chloride 17 mg/L and by a general Ca-HCO3 hydrochemical facies, which is maintained for most of the river stream, only varying in the terminal part where the river is diverted in a complex deltaic system affected by more significant evaporation and mixing with saline water evidenced by higher TDS and chloride content (up to 8198 and 4197 mg/L, respectively). Geochemical and isotopic maps have been drawn to visualize spatial gradients, which reflect the evolution of the river water composition at progressive distance from the source; more detailed maps were focused on the deltaic part in order to visualize the processes occurring in the transitional zone toward the Adriatic Sea. The data also highlight anthropogenic contributions, mainly represented by significant concentrations of nitrate (average 8 mg/L) and possibly arsenic (average 12 µg/L). These data allow the calculation of geochemical fluxes transferred from the river to the sea, and generally, they contribute to the definition of a "hydro-archive" which is useful to highlight ongoing variations in the related ecosystems.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s11356-014-3750-6

  4 / 5513 MEDLINE  
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[PMID]: 25774221
[Au] Autor:Komlósi K; Duga B; Hadzsiev K; Czakó M; Kosztolányi G; Fogarasi A; Melegh B
[Ad] Address:Department of Medical Genetics, Clinical Centre, University of Pecs, Szigeti Street 12, Pecs, H-7624 Hungary ; Szentágothai Research Centre, University of Pecs, Ifjusag Street 20, Pecs, H-7624 Hungary....
[Ti] Title:Phenotypic variability in a Hungarian patient with the 4q21 microdeletion syndrome.
[So] Source:Mol Cytogenet;8:16, 2015.
[Is] ISSN:1755-8166
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Interstitial deletions of 4q21 (MIM 613509) have already been reported in more than a dozen patients with deletions ranging from 2 to 15.1 Mb delineating a common phenotype including marked growth restriction, hypotonia, severe developmental delay with absent or delayed speech and distinctive facial features. A minimal critical region of 1.37 Mb accounting for the common features with 5 known genes (PRKG2, RASGEF1B, HNRNPD, HNRPDL, and ENOPH1) has been described so far. RESULTS: Here we report on a 5 year-old Hungarian girl presenting with severe developmental delay, good receptive language but absent spoken speech, short stature, dystrophy, hypotonia, distinctive facies including broad forehead, frontal bossing, downward slanting palpebral fissures, hypertelorism, hypoplastic ear-lobes, anteverted nostrils, short philtrum, small mouth, higharched palate, short, small hands and feet, distally narrowing fingers and clinodactyly. Cerebral MRI showed ventricular dilation and an increase in periventricular signal intensity. After extensive metabolic tests and exclusion of subtelomeric deletions array CGH analysis was performed using the Agilent Human Genome G3 SurePrint 8x60K Microarray (Agilent Technologies, USA), which detected a 4,85 Mb de novo interstitial deletion of 4q21.21-4q21.23. The clinical symptoms only partly overlap with reported 4q21 microdeletion cases. Among multiple annotated genes our patient is also haploinsufficient for the following genes: RASGEF1B being a strong candidate for the neurodevelopmental features and PRKG2 for severe growth delay. CONCLUSION: The first Hungarian case of 4q21 deletion adds to the phenotypic spectrum of this novel microdeletion syndrome and underlines the importance of array CGH to uncover the heterogeneous causes of intellectual disability.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Cu] Class update date: 150318
[Lr] Last revision date:150318
[Da] Date of entry for processing:150316
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1186/s13039-015-0118-7

  5 / 5513 MEDLINE  
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[PMID]: 25781807
[Au] Autor:Koppka J
[Ad] Address:Section d'Archéologie et Paléontologie, OCC Hôtel des Halles, CP 64, CH-2900 Porrentruy 2.; Email: jens@trilobiten.de.
[Ti] Title:Revision of the bivalvia from the upper jurassic reuchenette formation, northwest Switzerland-ostreoidea.
[So] Source:Zootaxa;3927(1):1-117, 2015.
[Is] ISSN:1175-5326
[Cp] Country of publication:New Zealand
[La] Language:eng
[Ab] Abstract:The current work is the first part of a taxonomic revision of the highly diverse Kimmeridgian bivalve fauna of the              Reuchenette Formation of northwestern Switzerland (Canton Jura). It provides a taxonomic, paleoecologic and bibliographic review of the eight oyster species characterizing the northern Helvetic shelf: Circunula n. gen. cotyledon (Contejean, 1859) (Gryphaeidae, ?Pycnodonteinae), Nanogyra (Nanogyra) nana (J. Sowerby, 1822), Nanogyra (Palaeogyra) reniformis (Goldfuss, 1833), Nanogyra (Palaeogyra) virgula (Deshayes, 1831) (Gryphaeidae, Exogyrinae), Helvetostrea n. gen. sequana (Thurmann & Etallon, 1862) (Flemingostreidae, Crassostreinae), Praeexogyra dubiensis (Contejean, 1859), Praeexogyra monsbeliardensis (Contejean, 1859) (Flemingostreidae, Liostreinae), and Actinostreon gregareum (J. Sowerby, 1815) (Arctostreidae, Palaeolophinae).The paper proposes two new genera: Circunula and Helvetostrea. Palaeogyra Mirkamalov, 1963, is considered a subgenus of Nanogyra Beurlen, 1958. Lectotypes are designated for six species: C. cotyledon, Praeexogyra acuminata, P. dubiensis, P. monsbeliardensis, H. caprina, H. sequana. The figured types of H. oxfordiana (Rollier, 1917) and N. auricularis (Münster in Goldfuss, 1833) are considered holotypes by monotypy. All types are refigured in drawings and/or photographs.        Early phases of shell ontogeny in general and the generic characters of Praeexogyra are revisited. Larval shells or their internal moulds are shown for six species: N. nana, N. reniformis, N. virgula, N. cf. auricularis, Praeexogyra cf. sandalinoides (de Loriol, 1901), and Actinostreon marshii (J. Sowerby, 1814). All of them are "Crassostrea"-like suggesting a planktic-planktotrophic mode of development. Circunula n. gen. shows a relatively high incidence of prosogyry (up to ca. 20% of studied specimens) during very early postlarval development. To a lesser extent, prosogyry has also been observed in species of Catinula, Praeexogyra and Pernostrea. Chomata are typical of early ontogenetic stages of Circunula n. gen., but they disappear during later growth stages.        Circunula n. gen. cotyledon is a typical early settler on hardgrounds but occurs also in subtidal soft-bottom environments attached to large shells. Nanogyra (N.) nana attached itself to all kinds of biogenous hard and soft substrates including algal stems and thalli. It is regularly found in calm to moderately energetic shallow marine paleoenvironments. Nanogyra (P.) reniformis frequently settled on the interior of empty bivalve shells. Nanogyra (P.) virgula was esentially a secondary soft-bottom dweller of shallow marine marls and lime muds. The species is often found concentrated in widely distributed (par)autochthonous lumachelles ("virgula marls" of authors) in the Upper Oxfordian, Upper Kimmeridgian and Tithonian. Praeexogyra dubiensis and P. monsbeliardensis occur in marly, shallow marine paleoenvironments. Praeexogyra dubiensis appears to have preferred attachment to small objects in a moderately energetic facies. In the study area it is also associated with algal meadows. Praeexogyra monsbeliardensis was preferentially gregarious in somewhat deeper and calmer paleoenvironments. The strongly chambered and probably fast growing Helvetostrea n. gen. sequana was adapted to moderate to high energetic shallow marine, marly habitats. It is frequently associated with corals and forms ostreoliths or small oyster buildups. Actinostreon gregareum usually lived gregariously but was also able to attach itself to algae on soft substrates. The species is known from calm marly to higher energetic coralline paleoenvironments.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.11646/zootaxa.3927.1.1

  6 / 5513 MEDLINE  
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[PMID]: 25647464
[Au] Autor:Martínez-Santos M; Probst A; García-García J; Ruiz-Romera E
[Ad] Address:Department of Chemical and Environmental Engineering, University of the Basque Country, Alameda Urquijo z/g, Bilbao 48013, Basque Country, Spain....
[Ti] Title:Influence of anthropogenic inputs and a high-magnitude flood event on metal contamination pattern in surface bottom sediments from the Deba River urban catchment.
[So] Source:Sci Total Environ;514:10-25, 2015 May 1.
[Is] ISSN:1879-1026
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:The purpose of this study was to assess the influence of anthropogenic factors (infrastructure construction and industrial and wastewater inputs) and hydrological factors (high-magnitude flood events) on metal and organic contamination and on the source variability of sediments taken from the Deba River and its tributaries. The pollution status was evaluated using a sequential extraction procedure (BCR 701), enrichment factor, individual and global contamination factors and a number of statistical analysis methods. Zn, Cu and Cr were found to have significant input from anthropogenic sources, with moderately severe enrichment, together with an extremely high potential risk of contamination. The principal scavenger of Cu and Cr was organic matter, whereas Zn was uniformly distributed among all non-residual fractions. For Fe, the anthropogenic contribution was more obviously detected in bulk sediments (<2mm) than in fine fractions (<63µm). Finally, the recent construction of a rail tunnel traversing Wealden Facies evaporites, together with intense rainfalls, was the main reason for the change in the source variability of bottom sediments and metal distribution in headwaters. The occurrence of a high-magnitude flood event resulted in a washout of the river bed and led to a general decrease in fine-grained sediment and metal concentrations in labile fractions of channel-bottom sediments, and a consequent downstream transfer of the pollution.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review

  7 / 5513 MEDLINE  
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[PMID]: 25112543
[Au] Autor:Sanmaneechai O; Likasitwattanakul S; Sangruchi T; Nishino I
[Ad] Address:Department of Pediatrics, Division of Neurology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. Electronic address: oranee141@gmail.com....
[Ti] Title:Ophthalmoplegia in congenital neuromuscular disease with uniform type 1 fiber.
[So] Source:Brain Dev;37(4):459-62, 2015 Apr.
[Is] ISSN:1872-7131
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Congenital neuromuscular disease with uniform type 1 fiber (CNMDU1) is a rare type of congenital myopathy. It is characterized by early onset of symptoms, mild proximal muscle weakness, hyporeflexia or areflexia, normal serum creatine kinase (CK) levels and myopathic electromyography finding, uniform type 1 fibers, and nonprogression. We report a 2-year-old boy who presented with congenital hypotonia, breathing and feeding difficulty, myopathic facies, proximal muscle weakness, ptosis, total external ophthalmoplegia and delayed motor developmental milestones. Normal serum muscle enzyme and short duration of motor unit potentials on electromyography were noted. Muscle biopsy showed uniformity of type 1 fibers (greater than 99%) and moderate variation in fiber size without specific structural abnormality. Total external ophthalmoplegia may be one of the important clinical manifestations of CNMDU1. It is important to recognize this disorder because it is nonprogressive in nature.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review

  8 / 5513 MEDLINE  
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[PMID]: 25762504
[Au] Autor:Löhr SC; Kennedy MJ
[Ad] Address:Sprigg Geobiology Centre, Department of Earth Sciences, University of Adelaide, North Terrace, Adelaide, South Australia 5005, Australia.
[Ti] Title:Micro-trace fossils reveal pervasive reworking of Pliocene sapropels by low-oxygen-adapted benthic meiofauna.
[So] Source:Nat Commun;6:6589, 2015.
[Is] ISSN:2041-1723
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Animal burrowers leave an indelible signature on the sedimentary record in most marine environments, with the seeming exception of low-oxygen environments. In modern sedimentary settings, however, sub-millimetre-sized benthic animals (meiofauna) are adapted to low oxygen and even sulfidic conditions. Almost nothing is known about their impact on ancient marine sediments because they leave few recognizable traces. Here we show, in classic Pliocene-aged anoxic facies from the Mediterranean, the first reported trace fossil evidence of meiofaunal activity and its relation to changing oxygenation. A novel approach utilizing electron imaging of ion-polished samples shows that meiofauna pervasively reworked sediment under oxygen-depleted conditions that excluded macrofauna, fragmenting organic laminae and emplacing 15- to 70-µm-diameter faecal pellets without macroscopically influencing the fabric. The extent of reworking raises the question: how pervasively altered are other sediments presently assumed to lack animal influence and how far into the geological record does this influence extend?
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1038/ncomms7589

  9 / 5513 MEDLINE  
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[PMID]: 25070745
[Au] Autor:Nofal A; Assaf M; Ghonemy S; Nofal E; Yosef A
[Ad] Address:Department of Dermatology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
[Ti] Title:Generalized eruptive keratoacanthoma: a diagnostic and therapeutic challenge.
[So] Source:Int J Dermatol;54(2):160-7, 2015 Feb.
[Is] ISSN:1365-4632
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Generalized eruptive keratoacanthoma (GEKA) is an extremely rare variant of keratoacanthoma that poses significant diagnostic and therapeutic challenges. PATIENTS: The study included three patients presenting with highly pruritic, generalized eruption of numerous small skin and flesh-colored follicular papules. They were mainly distributed on the face, neck, and trunk. Few larger nodules were also present. Mask-like facies, mucosal involvement, and ectropion were evident in two patients. Family history was irrelevant, and general examination was unremarkable. RESULTS: Histopathological examination revealed typical features of keratoacanthoma, particularly in the larger lesions. Routine laboratory tests were normal, and ultrasonography and computed tomography revealed no evidence of malignancy. Based on the clinicopathological correlation, the diagnosis of our cases was GEKA of Grzybowski. Acitretin 1 mg/kg per day and methotrexate 15 mg/week for three months were associated with mild or no response. Cyclophosphamide pulse therapy 1 g/month for six months was associated with complete clearance of the lesions in the first two patients, while the third was lost to follow-up after failure of acitretin therapy. CONCLUSION: Because of the extreme rarity of reported cases, the common absence of classic large lesions of keratoacanthoma, the atypical histological presentations in some cases, and absence of a uniformly effective therapeutic approach, we believe that GEKA still represents a diagnostic and therapeutic challenge. Cyclophosphamide pulse therapy is a promising alternative to oral retinoids.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1111/ijd.12308

  10 / 5513 MEDLINE  
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[PMID]: 25748506
[Au] Autor:De Giglio O; Quaranta A; Lovero G; Caggiano G; Montagna MT
[Ad] Address:Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Italy....
[Ti] Title:Mineral water or tap water? An endless debate.
[So] Source:Ann Ig;27(1):58-65, 2015 Jan-Feb.
[Is] ISSN:1120-9135
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:The consumption of mineral water has been increasing because of the frequent and unjustified reports of the water supply contamination. However some authors have shown that bottled waters are not always better than tap water. Mineral waters are more palatable for organoleptic characteristic because, being pure at source, they do not undergo disinfection treatments and are sometimes enriched with CO2. In fact, they are characterized by their microbial facies subject to changes during the production cycle which can contribute to their contamination. It is necessary to provide people with the tools necessary to operate a critical choice of the type of water to be consumed not exclusively for their organoleptic characteristics or marketing strategies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.7416/ai.2015.2023


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