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[PMID]: 29514062
[Au] Autor:Pan A; Lin X; Hemler E; Hu FB
[Ad] Address:Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health and State Key Laboratory of Environmental Health (incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, Ch
[Ti] Title:Diet and Cardiovascular Disease: Advances and Challenges in Population-Based Studies.
[So] Source:Cell Metab;27(3):489-496, 2018 Mar 06.
[Is] ISSN:1932-7420
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In this Minireview, we provide an epidemiologist's perspective on the debate and recent advances in determining the relationship between diet and cardiovascular health. We conclude that, in order to reduce the global burden of cardiovascular disease, there should be a greater emphasis on improving overall diet quality and food sources of macronutrients, such as dietary fats and carbohydrates. In addition, building a strong evidence base through high-quality intervention and observational studies is crucial for effective policy changes, which can greatly improve the food environment and population health.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review

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[PMID]: 29506517
[Au] Autor:Mosbah H; Chahdoura H; Kammoun J; Hlila MB; Louati H; Hammami S; Flamini G; Achour L; Selmi B
[Ad] Address:Laboratory of Bioresources: Integrative Biology and Valorization, Higher Institute of Biotechnology of Monastir, Avenue Taher Hadded BP 74, 5000, Monastir, Tunisia. mosbah_habib@yahoo.fr.
[Ti] Title:Rhaponticum acaule (L) DC essential oil: chemical composition, in vitro antioxidant and enzyme inhibition properties.
[So] Source:BMC Complement Altern Med;18(1):79, 2018 Mar 05.
[Is] ISSN:1472-6882
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore, xanthine oxidase (XO) is a key enzyme that catalyzes hypoxanthine and xanthine to uric acid which at high levels can lead to hyperuricemia which is an important cause of gout. Pancreatic lipase (PL) secreted into the duodenum plays a key role in the digestion and absorption of fats. For its importance in lipid digestion, PL represents an attractive target for obesity prevention. METHODS: The flowers essential oil of Rhaponticum acaule (L) DC (R. acaule) was characterized using gas chromatography-mass spectrometry (GC-MS). The antioxidant activities of R. acaule essential oil (RaEO) were also determined using 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), reducing power, phosphomolybdenum, and DNA nicking assays. The inhibitory power of RaEO against α-glucosidase, xanthine oxidase and pancreatic lipase was evaluated. Enzyme kinetic studies using Michaelis-Menten and the derived Lineweaver-Burk (LB) plots were performed to understand the possible mechanism of inhibition exercised by the components of this essential oil. RESULTS: The result revealed the presence of 26 compounds (97.4%). The main constituents include germacrene D (49.2%), methyl eugenol (8.3%), (E)-ß-ionone (6.2%), ß-caryophyllene (5.7%), (E,E)-α-farnesene (4.2%), bicyclogermacrene (4.1%) and (Z)-α-bisabolene (3.7%). The kinetic inhibition study showed that the essential oil demonstrated a strong α-glucosidase inhibiton and it was a mixed inhibitor. On the other hand, our results evidenced that this oil exhibited important xanthine oxidase inhibitory effect, behaving as a non-competitive inhibitor. The essential oil inhibited the turkey pancreatic lipase, with maximum inhibition of 80% achieved at 2 mg/mL. Furthermore, the inhibition of turkey pancreatic lipase by RaEO was an irreversible one. CONCLUSION: The results revealed that the RaEO is a new promising potential source of antioxidant compounds, endowed with good practical applications for human health.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Process
[do] DOI:10.1186/s12906-018-2145-5

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[PMID]: 29524001
[Au] Autor:Liu S; van der Schouw YT; Soedamah-Muthu SS; Spijkerman AMW; Sluijs I
[Ad] Address:Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, STR6.131, 3508 GA, Utrecht, The Netherlands.
[Ti] Title:Intake of dietary saturated fatty acids and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort: associations by types, sources of fatty acids and substitution by macronutrients.
[So] Source:Eur J Nutr;, 2018 Mar 09.
[Is] ISSN:1436-6215
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:PURPOSE: The association between dietary saturated fatty acids (SFA) intake and type 2 diabetes (T2D) remains unclear. This study aimed at investigating the association between SFA intake and T2D risk based on (1) individual SFA (differing in carbon chain length), (2) food sources of SFA and (3) the substituting macronutrients. METHODS: 37,421 participants from the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) cohort were included in this study. Baseline dietary intake was assessed by a validated food frequency questionnaire. T2D risks were estimated by Cox regression models adjusted for non-dietary and dietary covariates. RESULTS: 893 incident T2D cases were documented during 10.1-year follow-up. We observed no association between total SFA and T2D risk. Marginally inverse associations were found for lauric acid (HR per 1 SD of energy%, 95% CI 0.92, 0.85-0.99), myristic acid (0.89, 0.79-0.99), margaric acid (0.84, 0.73-0.97), odd-chain SFA (pentadecylic plus margaric acids; 0.88, 0.79-0.99), and cheese derived SFA (0.90, 0.83-0.98). Soft and liquid fats derived SFA was found related to higher T2D risk (1.08, 1.01-1.17). When substituting SFA by proteins, carbohydrates and polyunsaturated fatty acids, significantly higher risks of T2D were observed (HRs per 1 energy% ranging from 1.05 to 1.15). CONCLUSION: In this Dutch population, total SFA does not relate to T2D risk. Rather, the association may depend on the types and food sources of SFA. Cheese-derived SFA and individual SFA that are commonly found in cheese, were significantly related to lower T2D risks. We cannot exclude the higher T2D risks found for soft and liquid fats derived SFA and for substituting SFA with other macronutrients are influenced by residual confounding by trans fatty acids or limited intake variation in polyunsaturated fatty acids and vegetable protein.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher
[do] DOI:10.1007/s00394-018-1630-4

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[PMID]: 29367486
[Au] Autor:Miyazawa N; Yoshimoto H; Kurihara S; Hamaya T; Eguchi F
[Ad] Address:Faculty of Regional Environment Science, Tokyo University of Agriculture.
[Ti] Title:Improvement of Diet-induced Obesity by Ingestion of Mushroom Chitosan Prepared from Flammulina velutipes.
[So] Source:J Oleo Sci;67(2):245-254, 2018 Feb 01.
[Is] ISSN:1347-3352
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:The anti-obesity effects of mushroom chitosan prepared from Flammulina velutipes were investigated using an animal model with diet-induced obesity. In this study, 5-week-old imprinting control region (ICR) mice were divided into six groups of 10 mice each and fed different diets based on the MF powdered diet (standard diet) for 6 weeks: standard diet control group, high-fat diet control group (induced dietary obesity) consisting of the standard diet and 20% lard, and mushroom chitosan groups consisting of the high-fat diet with mushroom chitosan added at 100, 500, 1,000, and 2,000 mg/kg body weight. On the final day of the experiment, mean body weight was 39.1 g in the high-fat control group and 36.3 g in the 2,000 mg/kg mushroom chitosan group, compared to 35.8 g in the standard diet control group. In the mushroom chitosan groups, a dose-dependent suppression of weight gain and marked improvements in serum triglycerides, total cholesterol, LDL-cholesterol, and HDL-cholesterol were found. The mushroom chitosan groups showed fewer and smaller fat deposits in liver cells than the high-fat diet control group, and liver weight was significantly reduced. Glutamic oxaloacetic transaminase (GOT) and glutamate pyruvic transaminase (GPT), which are indices of the hepatic function, all showed dose-dependent improvement with mushroom chitosan administration. These results suggested that mushroom chitosan acts to suppress enlargement of the liver from fat deposition resulting from a high-fat diet and to restore hepatic function. The lipid content of feces showed a marked increase correlated with the mushroom chitosan dose. These findings suggest the potential use of mushroom chitosan as a functional food ingredient that contributes to the prevention or improvement of dietary obesity by inhibiting digestion and absorption of fats in the digestive tract and simultaneously promotes lipolysis in adipocytes.
[Mh] MeSH terms primary: Chitosan/administration & dosage
Chitosan/isolation & purification
Diet, High-Fat/adverse effects
Flammulina/chemistry
Obesity/prevention & control
Phytotherapy
[Mh] MeSH terms secundary: Adipocytes/metabolism
Administration, Oral
Animals
Anti-Obesity Agents
Chitosan/pharmacology
Disease Models, Animal
Dose-Response Relationship, Drug
Lipolysis/drug effects
Male
Mice, Inbred ICR
Non-alcoholic Fatty Liver Disease/prevention & control
Obesity/etiology
Obesity/metabolism
Weight Gain/drug effects
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Obesity Agents); 9012-76-4 (Chitosan)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180126
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess17159

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[PMID]: 28467207
[Au] Autor:Moon S
[Ad] Address:a Department of Nursing , College of Medicine, University of Ulsan , Ulsan , South Korea.
[Ti] Title:Unhealthy Lifestyle Behaviors in Korean People with Metabolic Syndrome.
[So] Source:J Community Health Nurs;34(2):69-79, 2017 Apr-Jun.
[Is] ISSN:1532-7655
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:This study identified factors associated with unhealthy lifestyle behaviors in people with metabolic syndrome in South Korea. The sample consisted of 1,207 subjects with metabolic syndrome from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014. High-risk alcohol consumption, smoking, aerobic physical activity, leisure physical activity, excessive carbohydrate intake, and fat intake were measured. A secondary data analysis was performed using chi-square tests and logistic regression. Gender was associated with all unhealthy behaviors. The number of metabolic syndrome components, a poor perceived health status, and attempts to control weight were associated with physical inactivity. Those findings may be helpful to develop a tailored lifestyle modification programs for people with metabolic syndrome.
[Mh] MeSH terms primary: Health Behavior
Metabolic Syndrome/psychology
[Mh] MeSH terms secundary: Adult
Aged
Alcohol Drinking/adverse effects
Alcohol Drinking/epidemiology
Chi-Square Distribution
Cross-Sectional Studies
Dietary Carbohydrates/administration & dosage
Dietary Carbohydrates/adverse effects
Dietary Fats/administration & dosage
Dietary Fats/adverse effects
Exercise
Female
Humans
Life Style
Logistic Models
Male
Middle Aged
Nutrition Surveys
Republic of Korea/epidemiology
Sex Factors
Smoking/adverse effects
Smoking/epidemiology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dietary Carbohydrates); 0 (Dietary Fats)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM; N
[Da] Date of entry for processing:170504
[St] Status:MEDLINE
[do] DOI:10.1080/07370016.2017.1304145

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[PMID]: 29517182
[Au] Autor:Wendolowicz A; Stefanska E; Ostrowska L
[Ad] Address:Medical University of Bialystok, Department of Dietetics and Clinical Nutrition, Bialystok, Poland
[Ti] Title:Influence of selected dietary components on the functioning of the human nervous system
[So] Source:Rocz Panstw Zakl Hig;69(1):15-21, 2018.
[Is] ISSN:0035-7715
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:The diet is directly connected not only with the physical status but also with the functioning of the brain and the mental status. The potentially beneficial nutrients with a protective effect on the nervous system function include amino acids (tryptophan, phenylalanine, tyrosine, taurine), glucose and vitamins C, E, D and beta-carotene, B group vitamins (vitamin B12, vitamin B6, vitamin B4, vitamin B1) and minerals (selenium, zinc, magnesium, sodium, iron, copper, manganese, iodine). The presence of antioxidants in the diet protects against oxidative damage to nervous system cells. Biochemical data indicate that polyunsaturated fatty acids such as arachidonic acid (AA), docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) as structural components of the nervous system play a key role in its function. The nutrition of the entire body also influences the production of neurotransmitters in the brain. A diet without an appropriate supply of protein, mineral nutrients or vitamins may result in a failure to form appropriately balanced numbers of neurotransmitters, which, as a result, may lead to neurotransmission dysfunction. This is the reason why proper nutrition is based on vegetables, fruits, whole-grain cereal products supplemented with products providing full-value protein (dairy products, fish, lean meat) and high-quality fat products (vegetable oils, fish fats).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review

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[PMID]: 29452095
[Au] Autor:Senatorov IS; Moniri NH
[Ad] Address:Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University Health Sciences Center, Mercer University, Atlanta, GA 30341, United States.
[Ti] Title:The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines.
[So] Source:Biochem Pharmacol;150:170-180, 2018 Feb 13.
[Is] ISSN:1873-2968
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:A dietary influence on cancer progression has been evident for many decades, and dietary fatty acids, particularly long chain mono- and polyunsaturated fatty acids, have been shown to play significant roles in influencing growth of a variety of human cancers. The discovery of the family of cell-surface free-fatty acid receptors, which include the long-chain fatty acid receptors FFA1 and FFA4, suggest that many of the effects of dietary fats could be receptor-mediated. FFA4 is ubiquitously expressed and has recently been shown to modulate a variety of important anti-inflammatory and metabolic processes. Since FFA4 is currently an attractive drug target for treatment of metabolic disorders such as diabetes and obesity, understanding its role in cancer progression is critical towards the drug discovery process. In this research update, the current body of knowledge on the role of this receptor in regulating cancer cell proliferation, migration, and invasion, as well as in vivo tumorigenesis is reviewed.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1802
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  8 / 68145 MEDLINE  
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[PMID]: 29280369
[Au] Autor:Barbarska O; Zielinska M; Pawlus B; Wesolowska A
[Ad] Address:Laboratory of Human Milk and Lactation Research, Regional Human Milk Bank in Holy Family Hospital, Department of Neonatology, Medical University of Warsaw, Poland
[Ti] Title:Characteristics of the regional human milk bank in Poland - donors, recipients and nutritional value of human milk
[So] Source:Rocz Panstw Zakl Hig;68(4):395-400, 2017.
[Is] ISSN:0035-7715
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Background: In case of shortage of breast milk despite proper lactation care or the poor state of the mother's health, breast milk from human milk bank is recommended for feeding preterm infants Objective: This study retrospectively evaluated the first year of the operation of the Regional Human Milk Bank Material and methods: Data concerning donors was collected in the human milk bank during the cooperation. The clinical characteristics of the recipients was made on the basis of medical documentation from the Holy Family Hospital in Warsaw, Poland. Analysis of nutritional value was performed with the human milk analyzer (MIRIS AB) Results: In the first year of activity, 45 voluntary donors established cooperation, donating from 650 to 32030 ml of human milk. The content of nutrients in milk provided by donors was variable - protein 0.4-1.5 g / 100 ml, fat 1.1-7.4 g / 100 ml, carbohydrates 6.3-7.9 g / 100 ml. The average length of using donated human milk was 4 days and the average volume of milk for one infant was 282 ml Conclusions: The donor profiles have a significant impact on the milk composition form HMB. The nutritional value can be improved by recruitment donors from mothers that gave birth prematurely and by beginning donation at earlier stages of lactation as soon as lactation is stabilized. In case of shortage of mothers own milk the immediate implementation of donors milk as a short-term support can significantly reduce the food intolerance incidence in the group of prematurely born infants
[Mh] MeSH terms primary: Milk Banks
Milk, Human/chemistry
Nutritive Value
[Mh] MeSH terms secundary: Dietary Carbohydrates/analysis
Dietary Fats/analysis
Dietary Proteins/analysis
Female
Humans
Infant Nutritional Physiological Phenomena
Infant, Newborn
Poland
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dietary Carbohydrates); 0 (Dietary Fats); 0 (Dietary Proteins)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:171228
[St] Status:MEDLINE

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[PMID]: 29265781
[Au] Autor:Czekajlo A; Rózanska D; Mandecka A; Konikowska K; Madalinska M; Regulska-Ilow B
[Ad] Address:Wroclaw Medical University, Faculty of Health Sciences, Department of Dietetics, Wroclaw, Poland
[Ti] Title:Comparison of nutritional value of "fruit and vegetables" and "western" dietary patterns identified in a group of cancer patients
[So] Source:Rocz Panstw Zakl Hig;68(4):365-373, 2017.
[Is] ISSN:0035-7715
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Background: Dietary patterns (DPs) are defined as the amounts, types and combinations of various food products in habitual diets and the frequency of their consumption. Dietary pattern analysis is usually performed in order to assess the combined effect of consumed food products on health Objective: The aim of the study was to assess and compare the nutritional value of dietary patterns identified in a group of patients staying on the oncological ward Material and methods: The study group consisted of 100 patients (51 women and 49 men) aged 19-83 years. Dietary intake was assessed using a food frequency questionnaire (FFQ) validated for the population of Lower Silesian Voivodeship Results: Factor analysis identified two main dietary patterns explaining 25.6% of variance. The "fruit and vegetables" DP consisted of vegetables, fruits, juices, unrefined grains and nuts, seeds and raisins. Instead, the "Western" DP was characterized by the consumption of high-fat and processed meat and poultry, fried fish, refined grains, honey and sugar, fats, sweets, beverages and chips. While higher scores for "fruit and vegetables" pattern were associated with increased intake of dietary fiber, antioxidant vitamins, folic acid and decreased glycemic load per 1000 kcal and sodium intake, for "Western" pattern observed relationships were opposite. Women were more likely to have higher factor scores for "fruit and vegetables" DP and lower factor scores for "Western" DP than men Conclusions: Dietary patterns identified in the study group differed in terms of nutritional value, in spite of similar macronutrient content in the diet. "Western" DP was characterized by lower nutritional value than "fruit and vegetables" dietary pattern.
[Mh] MeSH terms primary: Diet, Western
Feeding Behavior
Fruit
Neoplasms/therapy
Nutritive Value
Vegetables
[Mh] MeSH terms secundary: Adult
Aged
Aged, 80 and over
Energy Intake
Factor Analysis, Statistical
Female
Humans
Male
Middle Aged
Nutrition Assessment
Poland
Sex Factors
Surveys and Questionnaires
Young Adult
[Pt] Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:171222
[St] Status:MEDLINE

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[PMID]: 29516225
[Au] Autor:van der Velde LA; Nguyen AN; Schoufour JD; Geelen A; Jaddoe VWV; Franco OH; Voortman T
[Ad] Address:Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
[Ti] Title:Diet quality in childhood: the Generation R Study.
[So] Source:Eur J Nutr;, 2018 Mar 07.
[Is] ISSN:1436-6215
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:PURPOSE: We aimed to evaluate diet quality of 8-year-old children in the Netherlands, to identify sociodemographic and lifestyle correlates of child diet quality, and to examine tracking of diet quality from early to mid-childhood. METHODS: For 4733 children participating in a population-based cohort, we assessed dietary intake using a validated food-frequency questionnaire at a median age of 8.1 years (interquartile range 8.0-8.2) (2011-2014). Based on dietary guidelines, we developed and validated a food-based diet quality score for children consisting of ten components (score 0-10): sufficient intake of vegetables; fruit; whole grains; fish; legumes; nuts; dairy; oils and soft fats; and low intake of sugar-containing-beverages; and high-fat and processed meat. RESULTS: We observed a mean (± SD) diet quality score of 4.5 (± 1.2) out of a maximum of 10. On average, intake of legumes, nuts, and oils or soft fats was below recommendations, whereas intake of sugar-containing beverages and high-fat or processed meat was higher than recommended. The main factors associated with higher diet quality were higher maternal educational level (ß = 0.29, 95% CI 0.21, 0.37 versus low education), higher household income (ß = 0.15, 95% CI 0.05, 0.25 versus low income), no maternal smoking (ß = 0.13, 95% CI 0.02, 0.25 versus current smoking), and less screen time (ß = 0.31, 95% CI 0.24, 0.38)-all independent of each other. For children with available dietary data at age 1 year (n = 2608), we observed only weak tracking of diet quality from early to mid-childhood (Pearson's r = 0.19, k = 0.11 for extreme quartiles). CONCLUSION: Overall diet quality of 8-year-old children did not conform to dietary guidelines, especially for children having more screen time, children of lower educated or smoking mothers, or from lower-income households.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1007/s00394-018-1651-z


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