Database : MEDLINE
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[PMID]: 25834341
[Au] Autor:Wang ZQ; Chen LQ; Yuan Y; Wang WP; Niu ZX; Yang YS; Cai J
[Ad] Address:Zhi-Qiang Wang, Long-Qi Chen, Yong Yuan, Wen-Ping Wang, Zhong-Xi Niu, Yu-Shang Yang, Jie Cai, Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China....
[Ti] Title:Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis.
[So] Source:World J Gastroenterol;21(12):3720-30, 2015 Mar 28.
[Is] ISSN:2219-2840
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:AIM: To evaluate the benefit and safety of sivelestat (a neutrophil elastase inhibitor) administration in patients undergoing esophagectomy. METHODS: Online databases including PubMed, EMBASE, the Cochrane Library, Web of Knowledge, and Chinese databases (Wanfang database, VIP and CNKI) were searched systematically up to November 2013. Randomized controlled trials and high-quality comparative studies were considered eligible for inclusion. Three reviewers evaluated the methodological quality of the included studies, and Stata 12.0 software was used to analyze the extracted data. The risk ratio (RR) was used to express the effect size of dichotomous outcomes, and mean difference (MD) or standardized mean difference was used to express the effect size of continuous outcomes. RESULTS: Thirteen studies were included in this systematic review and nine studies were included in the meta-analysis. The duration of mechanical ventilation was significantly decreased in the sivelestat group on postoperative day 5 [I (2) = 76.3%, SMD = -1.41, 95%CI: -2.63-(-0.19)]. Sivelestat greatly lowered the incidence of acute lung injury in patients after surgery (I (2) = 0%, RR = 0.27, 95%CI: 0.08-0.93). However, it did not decrease the incidence of pneumonia, intensive care unit stay or postoperative hospital stay, and did not increase the incidence of complications such as anastomotic leakage, recurrent nerve palsy, wound infection, sepsis and catheter-related fever. CONCLUSION: A neutrophil elastase inhibitor is beneficial in patients undergoing esophagectomy. More high quality, large sample, multi-center and randomized controlled trials are needed to validate this effect.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3748/wjg.v21.i12.3720

  2 / 243127 MEDLINE  
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[PMID]: 25834659
[Au] Autor:Koenig KL; Alassaf W; Burns MJ
[Ad] Address:University of California, Irvine, Department of Emergency Medicine, Orange, California.
[Ti] Title:Identify-isolate-inform: a tool for initial detection and management of measles patients in the emergency department.
[So] Source:West J Emerg Med;16(2):212-9, 2015 Mar.
[Is] ISSN:1936-9018
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Measles (rubeola) is a highly contagious airborne disease that was declared eliminated in the U.S. in the year 2000. Only sporadic U.S. cases and minor outbreaks occurred until the larger outbreak beginning in 2014 that has become a public health emergency. The "Identify-Isolate-Inform" tool will assist emergency physicians to be better prepared to detect and manage measles patients presenting to the emergency department. Measles typically presents with a prodrome of high fever, and cough/coryza/conjunctivitis, sometimes accompanied by the pathognomonic Koplik spots. Two to four days later, an erythematous maculopapular rash begins on the face and spreads down the body. Suspect patients must be immediately isolated with airborne precautions while awaiting laboratory confirmation of disease. Emergency physicians must rapidly inform the local public health department and hospital infection control personnel of suspected measles cases.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.5811/westjem.2015.3.25678

  3 / 243127 MEDLINE  
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[PMID]: 25834634
[Au] Autor:Martorano Raimundo S; Amaku M; Massad E
[Ad] Address:School of Medicine, University of São Paulo and LIM01 HC-FMUSP, Avenida Doutor Arnaldo 455, Cerqueira César, 01246-903 São Paulo, SP, Brazil.
[Ti] Title:Equilibrium analysis of a yellow Fever dynamical model with vaccination.
[So] Source:Comput Math Methods Med;2015:482091, 2015.
[Is] ISSN:1748-6718
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We propose an equilibrium analysis of a dynamical model of yellow fever transmission in the presence of a vaccine. The model considers both human and vector populations. We found thresholds parameters that affect the development of the disease and the infectious status of the human population in the presence of a vaccine whose protection may wane over time. In particular, we derived a threshold vaccination rate, above which the disease would be eradicated from the human population. We show that if the mortality rate of the mosquitoes is greater than a given threshold, then the disease is naturally (without intervention) eradicated from the population. In contrast, if the mortality rate of the mosquitoes is less than that threshold, then the disease is eradicated from the populations only when the growing rate of humans is less than another threshold; otherwise, the disease is eradicated only if the reproduction number of the infection after vaccination is less than 1. When this reproduction number is greater than 1, the disease will be eradicated from the human population if the vaccination rate is greater than a given threshold; otherwise, the disease will establish itself among humans, reaching a stable endemic equilibrium. The analysis presented in this paper can be useful, both to the better understanding of the disease dynamics and also for the planning of vaccination strategies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1155/2015/482091

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[PMID]: 25830998
[Au] Autor:Couto DV; Medeiros MZ; Hans Filho G; Lima AM; Barbosa AB; Vicari CF
[Ad] Address:Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil....
[Ti] Title:Brazilian Spotted Fever: the importance of dermatological signs for early diagnosis.
[So] Source:An Bras Dermatol;90(2):248-50, 2015 Mar-Apr.
[Is] ISSN:1806-4841
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Brazilian spotted fever is an acute febrile infectious disease caused by Rickettsia rickettsii, transmitted by tick bite. As this disease is rare and has high mortality rates in Brazil, the clinical aspects and epidemiological data may help the diagnosis. We report a case of Brazilian spotted fever in a 19-year-old patient who presented maculopapular exanthema in the palmar region and upper limbs, lymphadenopathy, fever, chills, headache, conjunctival hyperemia, nausea, vomiting, dyspnea, myalgia, developing neurological signs and abdominal pain. He was treated with doxycycline with clinical improvement. We emphasize the importance of the recognition of this disease by dermatologists as cutaneous manifestations are the key findings to establish early diagnosis and prevent complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 25830997
[Au] Autor:Resende C; Araújo C; Duarte Mda L; Vieira AP; Brito C
[Ad] Address:Hospital de Braga, Braga, Portugal....
[Ti] Title:Kikuchi´s disease of the xanthomathous type with cutaneous manifestations.
[So] Source:An Bras Dermatol;90(2):245-7, 2015 Mar-Apr.
[Is] ISSN:1806-4841
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:Kikuchi's disease is a benign, self-limiting disease, whose pathogenesis remains unknown. Patients most often present with cervical lymphadenopathy, sometimes associated with fever and leukopenia. It has been reported that up to 40% of patients with Kikuchi's disease have also cutaneous eruptions, but no specific skin changes have been described. Kikuchi's disease can be subclassified into three histologic subtypes: a proliferative type, a necrotizing type and a xantomathous type. Most patients with Kikuchi's disease require no specific treatment, because the disease regresses spontaneously, within a few weeks to months. We report a case of a 31-year-old woman with xanthomatous type of Kikuchi's disease, whose first manifestation was the onset of erythematous papules with central suppuration on her face and on her left hand.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review

  6 / 243127 MEDLINE  
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[PMID]: 25667056
[Au] Autor:Thompson CN; Blacksell SD; Paris DH; Arjyal A; Karkey A; Dongol S; Giri A; Dolecek C; Day N; Baker S; Thwaites G; Farrar J; Basnyat B
[Ad] Address:Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom; Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; The London School of Hygiene and Tropical M...
[Ti] Title:Undifferentiated febrile illness in kathmandu, Nepal.
[So] Source:Am J Trop Med Hyg;92(4):875-8, 2015 Apr 1.
[Is] ISSN:1476-1645
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Undifferentiated febrile illnesses (UFIs) are common in low- and middle-income countries. We prospectively investigated the causes of UFIs in 627 patients presenting to a tertiary referral hospital in Kathmandu, Nepal. Patients with microbiologically confirmed enteric fever (218 of 627; 34.8%) randomized to gatifloxacin or ofloxacin treatment were previously reported. We randomly selected 125 of 627 (20%) of these UFI patients, consisting of 96 of 409 (23%) cases with sterile blood cultures and 29 of 218 (13%) cases with enteric fever, for additional diagnostic investigations. We found serological evidence of acute murine typhus in 21 of 125 (17%) patients, with 12 of 21 (57%) patients polymerase chain reaction (PCR)-positive for Rickettsia typhi. Three UFI cases were quantitative PCR-positive for Rickettsia spp., two UFI cases were seropositive for Hantavirus, and one UFI case was seropositive for Q fever. Fever clearance time (FCT) for rickettsial infection was 44.5 hours (interquartile range = 26-66 hours), and there was no difference in FCT between ofloxacin or gatifloxacin. Murine typhus represents an important cause of predominantly urban UFIs in Nepal, and fluoroquinolones seem to be an effective empirical treatment.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review
[do] DOI:10.4269/ajtmh.14-0709

  7 / 243127 MEDLINE  
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[PMID]: 25834520
[Au] Autor:Ajayi NA; Ukwaja KN; Ifebunandu NA; Nnabu R; Onwe FI; Asogun DA
[Ad] Address:Department of Internal Medicine, Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria....
[Ti] Title:Lassa fever - full recovery without ribavarin treatment: a case report.
[So] Source:Afr Health Sci;14(4):1074-7, 2014 Dec.
[Is] ISSN:1729-0503
[Cp] Country of publication:Uganda
[La] Language:eng
[Ab] Abstract:BACKGROUND: Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute hemorrhagic fever. It is treated using ribavarin. Surviving Lassa fever without receiving the antiviral drug ribavarin is rare. Only few cases have been documented to date. CASE PRESENTATION: We report a case of a 59-year old female with fever who was initially thought to have acute pyelonephritis and sepsis syndrome with background malaria. Further changes in her clinical state and laboratory tests led to a suspicion of Lassa fever. However at the time her laboratory confirmatory test for Lassa fever returned, her clinical state had improved and she made full recovery without receiving ribavarin. Her close contacts showed no evidence of Lassa virus infection. CONCLUSION: This report adds to the literature on the natural history of Lassa fever; and that individuals may survive Lassa fever with conservative management of symptoms of the disease and its complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.4314/ahs.v14i4.40

  8 / 243127 MEDLINE  
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[PMID]: 25834496
[Au] Autor:Hekimoglu HC; Demirci NA
[Ad] Address:Kastamonu Dr. Münif Islamoglu Hospital, Infectious Diseases and Clinical Microbiology Department.
[Ti] Title:Evaluation of cases with a preliminary diagnosis of Crimean- Congo hemorrhagic fever and comparison of characteristics in patients admitted to a secondary care hospital in Kastamonu, Turkey.
[So] Source:Afr Health Sci;14(4):873-81, 2014 Dec.
[Is] ISSN:1729-0503
[Cp] Country of publication:Uganda
[La] Language:eng
[Ab] Abstract:BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is an endemic disease in Turkey. The clinical presentation and laboratory findings are not specific especially in cases without hemorrhagic findings. OBJECTIVE: We aimed to evaluate CCHF cases and compare them with non-CCHF cases in terms of their characteristics during admission. METHODS: Cases with a preliminary diagnosis of CCHF at a secondary care hospital in Kastamonu in 2013 were evaluated, retrospectively. Cases testing RNA/IgM positive were considered as CCHF. Cases testing both RNA and IgM negative were considered as non-CCHF. The two groups were then compared in terms of their clinical, laboratory and epidemiological characteristics during admission. RESULTS: A total of 41 cases were tested and CCHF was found in 46.3% of cases. Fatality was 5.3% in CCHF cases. The frequency of tick bites and CK elevation in CCHF cases was significantly higher than non-CCHF cases (p<0.05). There were no significant differences between the two groups regarding other characteristics (p>0.05). CONCLUSIONS: In cases with a preliminary diagnosis of CCHF, especially in cases without a history of tick bite and with normal CK levels during admission, performing tests for the differential diagnosis may be advisable without waiting for the results of tests for CCHF.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.4314/ahs.v14i4.15

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[PMID]: 25829649
[Au] Autor:Aguirre JL; Jurado M; Porres-Aguilar M; Olivas-Chacon C; Porres-Muñoz M; Mukherjee D; Taveras J
[Ad] Address:Cardiology Care Consultants, El Paso, Texas (Aguirre, Jurado); the Department of Internal Medicine (Porres-Aguilar), Department of Radiology (Olivas-Chacon), and Division of Cardiovascular Diseases (Mukherjee), Texas Tech University Health Sciences Center/Paul L. Foster School of Medicine, El Paso, ...
[Ti] Title:Acute nonrheumatic streptococcal myocarditis resembling ST-elevation acute myocardial infarction in a young patient.
[So] Source:Proc (Bayl Univ Med Cent);28(2):188-90, 2015 Apr.
[Is] ISSN:0899-8280
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Acute myocarditis can be induced by various concomitant disease processes including infections. Most of these cases are viral in origin; however, bacterial infections are also implicated to a lesser degree. Group A streptococcus is a frequent culprit in bacterial-induced myocarditis. Its diagnosis is suspected by the presence of signs and symptoms of rheumatic fever as established by the Jones criteria. The development and refinement of current diagnostic tools has improved our ability to identify specific pathogens. It has been found that group A streptococcus may be responsible for more cases of infection-induced acute myocarditis than previously thought, and often without the clinical features of rheumatic fever. We present the case of a 43-year-old man hospitalized with chest pain that was initially diagnosed as an acute ST-elevation myocardial infarction. Further evaluation confirmed that his chief complaint was due to acute nonrheumatic streptococcal myocarditis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Da] Date of entry for processing:150401
[St] Status:PubMed-not-MEDLINE

  10 / 243127 MEDLINE  
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[PMID]: 25829968
[Au] Autor:Bubshait DK; Albuali WH; Yousef AA; Obeid OE; Alkharsah KR; Hassan MI; Vatte C; Alzahrani AJ; Bukhari H
[Ad] Address:Department of Pediatrics, University of Dammam, Dammam, Saudi Arabia....
[Ti] Title:Clinical description of human bocavirus viremia in children with LRTI, Eastern Province, Saudi Arabia.
[So] Source:Ann Thorac Med;10(2):146-9, 2015 Apr-Jun.
[Is] ISSN:1817-1737
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Human bocavirus (HBoV) is a major etiology of lower respiratory tract infection (LRTI) in young children. We tested 149 patients admitted to King Fahd Hospital of the University with diagnosis of LRTI. Viremia caused by the different studied viruses was detected in 31.5% of the total cases by Real-time Polymerase chain reaction. We report five patients who were positive for HBoV in serum samples. Clinical presentation ranged from mild to severe disease as one of them required admission to intensive care unit. Wheezing was a striking feature in most of our patients, but fever was not a consistent finding.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150404
[Lr] Last revision date:150404
[Da] Date of entry for processing:150401
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/1817-1737.151437


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