Database : MEDLINE
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[PMID]: 25949983
[Au] Autor:Mishra V; Harbada R; Sharma A; Mishra M
[Ad] Address:Department of Medicine, Bombay Hospital Institute of Medical Sciences and Research, Mumbai, Maharashtra, India....
[Ti] Title:Hypokalemic quadriparesis in dengue.
[So] Source:J Family Med Prim Care;4(2):278-9, 2015 Apr-Jun.
[Is] ISSN:2249-4863
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Dengue infection is the leading cause of illness and death in tropical and subtropical regions of the world. The common complications associated with dengue fever are usual hematological abnormalities, shock, and organ failure. The neurological complications of dengue are uncommon. However, evidence of dengue virus neurotropism and complications has been slowly but surely rising as seen from increased literature on this subject over the last decade. We report an uncommon case of hypokalemic quadriparesis with dengue that had a favorable outcome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Da] Date of entry for processing:150507
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/2249-4863.154676

  2 / 244514 MEDLINE  
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[PMID]: 25949972
[Au] Autor:Orimadegun AE; Ilesanmi KS
[Ad] Address:Institute of Child Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.
[Ti] Title:Mothers' understanding of childhood malaria and practices in rural communities of Ise-Orun, Nigeria: implications for malaria control.
[So] Source:J Family Med Prim Care;4(2):226-31, 2015 Apr-Jun.
[Is] ISSN:2249-4863
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Regular evaluations of communities' understanding of malaria-related practices are essential for control of the disease in endemic areas. This study was aimed at investigating the perceptions, prevention and treatments practices for childhood malaria by mothers in rural communities. MATERIALS AND METHODS: We conducted a community-based cross-sectional study at rural communities of Ise-Orun local Government area, Nigeria. We randomly sampled 422 mothers of children less than 5 years and administered a validated questionnaire to assess their perceptions and practices relating to childhood malaria. We used a 10-point scale to assess perception and classified it as good (≥5) or poor (<5). Predictive factors for poor perceptions were identified using logistic regression. RESULTS: Approximately 51% of the mothers had poor perception and 14.2% ascribed malaria illness to mosquito bite only. Majority (85.8%) of the mothers practiced malaria preventive measures, including: Insecticide treated nets (70.0%), chemoprophylaxis (20.1%) and environmental sanitation (44.8%). Of the 200 mothers whose children had malaria fever within the 3 months prior to the study visits, home treatment was adopted by 87.5%. Local herbal remedies were combined with orthodox medicine in the treatments of malaria for 91.5% of the children. The main reasons for not seeking medical treatment at existing formal health facilities were "high cost", "challenges of access to facilities" and "mothers' preference for herbal remedies". Lack of formal education was the only independent predictor of poor malaria perceptions among mothers (OR = 1.91, 95% CI = 1.18, 3.12). CONCLUSIONS: Considerable misconceptions about malaria exist among mothers in the rural communities. The implications for malaria control in holoendemic areas are highlighted.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Da] Date of entry for processing:150507
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/2249-4863.154655

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[PMID]: 25947235
[Au] Autor:Ibrahim IM; Dokhan AL; El-Sessy AA; Eltaweel MF
[Ad] Address:Cardiothoracic surgery department, Faculty of Medicine, Menoufia University, Yassin Abd El-Ghaffar Street, 32511, Shepin El-Kom, Menoufia, Egypt. islammoheb@hotmail.com....
[Ti] Title:Povidone-iodine pleurodesis versus talc pleurodesis in preventing recurrence of malignant pleural effusion.
[So] Source:J Cardiothorac Surg;10(1):64, 2015.
[Is] ISSN:1749-8090
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Malignant pleural effusions continue to be a common problem in patients with metastatic disease, leading to a significant reduction in quality of life with progressive dyspnea, dry cough, chest pain and reduced physical activity. This study was conducted to compare the efficacy, safety, and outcome of Talc Powder Pleurodesis (TPP) with Povidone-iodine Pleurodesis (PIP) through a chest drain as a palliative preventive treatment of recurrent malignant pleural effusion. METHODS: A total of 39 neoplastic patients with recurrent malignant pleural effusion were enrolled in a prospective randomized trial. Twenty-one patients received Talc pleurodesis (group A), and eighteen patients (group B) received Povidone-iodine pleurodesis. The continuous variables were expressed as mean values ± standard deviation (SD) and compared using the unpaired t-test. The discrete variables were expressed as percentage and compared using the chi-square test (χ(2)) test. p-values of less than 0.05 were considered significant. RESULTS: Our study included 11 males and 28 females, the mean age was (71.0 ± 5.0) years for group A and (70.9 ± 5.1) years for group B (non-significant). Post-procedure analgesic requirements were recorded in both groups. Four patients in each group had fever (>38°C) within 48 hours of the procedure. Both groups achieved good symptomatic relief. There were no in-hospital deaths. The mean post-procedure hospital stay was (4.7 ± 1.2) days for group A and (4.2 ± 1.0) for group B (non-significant). At follow-up recurrence of significant pleural effusion requiring intervention was noted in four and five patients in group A and group B, respectively (non-significant difference). CONCLUSION: Povidone-iodine pleurodesis can be considered as a good alternative to Talc pleurodesis for recurrent malignant pleural effusion. The drug is available, cost effective, safe and can be administered through an intercostal drain and repeated if necessary.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1186/s13019-015-0270-5

  4 / 244514 MEDLINE  
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[PMID]: 25949264
[Au] Autor:Dias CN; Alves LP; Rodrigues KA; Brito MC; Rosa Cdos S; do Amaral FM; Monteiro Odos S; Andrade EH; Maia JG; Moraes DF
[Ad] Address:Programa de Pós-Graduação em Saúde e Ambiente, Universidade Federal do Maranhão, 65085-580 São Luís, MA, Brazil....
[Ti] Title:Chemical Composition and Larvicidal Activity of Essential Oils Extracted from Brazilian Legal Amazon Plants against Aedes aegypti L. (Diptera: Culicidae).
[So] Source:Evid Based Complement Alternat Med;2015:490765, 2015.
[Is] ISSN:1741-427X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The mosquito Aedes aegypti L. (Diptera: Culicidae) is the major vector of dengue and chikungunya fever. The lack of effective therapies and vaccines for these diseases highlights the need for alternative strategies to control the spread of virus. Therefore, this study investigated the larvicidal potential of essential oils from common plant species obtained from the Chapada das Mesas National Park, Brazil, against third instar A. aegypti larvae. The chemical composition of these oils was determined by gas chromatography coupled to mass spectrometry. The essential oils of Eugenia piauhiensis Vellaff., Myrcia erythroxylon O. Berg, Psidium myrsinites DC., and Siparuna camporum (Tul.) A. DC. were observed to be mainly composed of sesquiterpene hydrocarbons. The essential oil of Lippia gracilis Schauer was composed of oxygenated monoterpenes. Four of the five tested oils were effective against the A. aegypti larvae, with the lethal concentration (LC50) ranging from 230 to 292 mg/L after 24 h of exposure. Overall, this work demonstrated the possibility of developing larvicidal products against A. aegypti by using essential oils from the flora of the Brazilian Legal Amazon. This in turn demonstrates the potential of using natural resources for the control of disease vectors.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Da] Date of entry for processing:150507
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1155/2015/490765

  5 / 244514 MEDLINE  
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[PMID]: 25949950
[Au] Autor:Nasrin M; Dash PR; Ali MS
[Ad] Address:Department of Pharmacy Jahangirnagar University, Bangladesh.
[Ti] Title:In Vitro antibacterial and in Vivo cytotoxic activities of Grewia paniculata.
[So] Source:Avicenna J Phytomed;5(2):98-104, 2015 Mar-Apr.
[Is] ISSN:2228-7930
[Cp] Country of publication:Iran
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Grewia paniculata (Family: Malvaceae) has been used to treat inflammation, respiratory disorders and fever. It is additionally employed for other health conditions including colds, diarrhea and as an insecticide in Bangladesh. The aim of the present study was to investigate the antibacterial and cytotoxic activities of different extracts of Grewia paniculata. MATERIALS AND METHODS: The antibacterial activity was evaluated against both gram negative and gram positive bacteria using disc diffusion method by determination of the diameter of zone of inhibition. Cytotoxic activity was performed by brine shrimp (Artemia salina) lethality bioassay. RESULTS: In disc diffusion method, all the natural products (400 µg/disc) showed moderate to potent activity against all the tested bacteria. The ethanol extract of bark (EEB) and ethanol fraction of bark (EFB) (400 µg/disc) exhibited highest activity against Shigella dysenteriae with a zone of inhibition of 23±1.63 mm and 23±1.77 mm respectively. In the brine shrimp lethality bioassay all the extracts showed moderate cytotoxic activity when compared with the standard drug vincristin sulphate. For example, LC50 value of the ethanol fraction of bark (EFB) was 3.01 µg/ml while the LC50 of vincristine sulphate was 0.52 µg/ml. CONCLUSIONS: The results suggest that all the natural products possess potent antibacterial and moderate cytotoxic.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Da] Date of entry for processing:150507
[St] Status:PubMed-not-MEDLINE

  6 / 244514 MEDLINE  
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[PMID]: 25899080
[Au] Autor:Kosoy OI; Lambert AJ; Hawkinson DJ; Pastula DM; Goldsmith CS; Hunt DC; Staples JE
[Ti] Title:Novel thogotovirus associated with febrile illness and death, United States, 2014.
[So] Source:Emerg Infect Dis;21(5), 2015 May.
[Is] ISSN:1080-6059
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness. His condition did not improve. Multiorgan failure developed, and he died 11 days after illness onset from cardiopulmonary arrest. Molecular and serologic testing results for known tickborne pathogens were negative. However, testing of a specimen for antibodies against Heartland virus by using plaque reduction neutralization indicated the presence of another virus. Next-generation sequencing and phylogenetic analysis identified the virus as a novel member of the genus Thogotovirus.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1504
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3201/eid2105.150150

  7 / 244514 MEDLINE  
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[PMID]: 25794128
[Au] Autor:Hartman R; Hawkins JF; Adams SB; Moore GE; Fessler JF
[Ad] Address:Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
[Ti] Title:Cryptorchidectomy in equids: 604 cases (1977-2010).
[So] Source:J Am Vet Med Assoc;246(7):777-84, 2015 Apr 1.
[Is] ISSN:1943-569X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To evaluate the management of equids undergoing cryptorchidectomy at a referral hospital. DESIGN: Retrospective case series. ANIMALS: 604 client-owned equids. PROCEDURES: Medical records of all equids undergoing surgical treatment of cryptorchidism from 1977 to 2010 were retrospectively reviewed. Analyses of breed, location of retained testes, accuracy of palpation per rectum for determining the location of retained testes, surgical technique, and postoperative complications were performed. RESULTS: The most frequently affected breed was the Quarter Horse (282/604 [47%]), which was significantly overrepresented. Of the 604 equids, 90 (15%) had undergone previous surgical attempts at castration. Preoperative palpation per rectum was performed in 395/604 (65.4%) patients, and was accurate in predicting the location of the retained testes in 354/395 (89.6%). Surgeons were significantly more likely to be incorrect in determining the location of the retained testis by means of palpation per rectum in patients that had undergone a prior attempt at castration. For equids with abdominal cryptorchidism (360/604 [59.6%]), the most common surgical technique was noninvasive cryptorchidectomy (298/360 [82.8%]). In unilateral cryptorchids (521/604 [86.3%]), the 2 most common sites were left abdominal (184/521 [35.3%]) and right inguinal (148/521 [28.4%]). For bilateral retention (80/604 [13.2%]), abdominal cryptorchidism was most common (48/80 [60%]). Fever was present in 138/324 (43%) equids on the first day after surgery. Postoperative fever was not significantly associated with any variables evaluated. Including postoperative (≤ 24 hours) fever, 150 of 604 (25%) patients developed postoperative complications. Excluding postoperative fever, 18 of 604 (3%) patients developed major postoperative complications; complications in 10 of 604 patients were deemed surgically related, and 3 of 604 patients died. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that cryptorchidectomy in equids performed with a variety of surgical approaches was associated with minimal postoperative complications. A history of previous attempts at castration decreased the ability to accurately predict the location of the retained testis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.2460/javma.246.7.777

  8 / 244514 MEDLINE  
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[PMID]: 25788715
[Au] Autor:Relich RF; Manaloor JJ; Fox TG
[Ad] Address:Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA rrelich@iupui.edu.
[Ti] Title:Photo quiz: Diarrhea and fever in a child returning from Africa. Answer to photo quiz: Enteric fever.
[So] Source:J Clin Microbiol;53(4):1053, 1461, 2015 Apr.
[Is] ISSN:1098-660X
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:EDITORIAL
[Em] Entry month:1503
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1128/JCM.01412-13

  9 / 244514 MEDLINE  
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[PMID]: 25673791
[Au] Autor:Howell BA; Azar MM; Landry ML; Shaw AC
[Ad] Address:Yale School of Medicine, Department of Internal Medicine, New Haven, Connecticut, USA benjamin.howell@yale.edu....
[Ti] Title:Toscana virus encephalitis in a traveler returning to the United States.
[So] Source:J Clin Microbiol;53(4):1445-7, 2015 Apr.
[Is] ISSN:1098-660X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In Italy, Toscana virus is the most common cause of meningitis from May to October. Though only a few cases have been reported in U.S. travelers returning from Europe, most cases are likely unrecognized due to lack of familiarity with the disease. Here, we describe the case of an 82-year-old man presenting with fever, profound weakness, and hearing loss after returning to the United States following a 2-week summertime vacation in southern Italy who was ultimately diagnosed with Toscana virus encephalitis. This case should alert clinicians to the possibility of Toscana virus infection in returning travelers and provides information on how to obtain testing if Toscana virus is suspected.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1128/JCM.03498-14

  10 / 244514 MEDLINE  
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[PMID]: 25588659
[Au] Autor:Pal S; Dauner AL; Valks A; Forshey BM; Long KC; Thaisomboonsuk B; Sierra G; Picos V; Talmage S; Morrison AC; Halsey ES; Comach G; Yasuda C; Loeffelholz M; Jarman RG; Fernandez S; An US; Kochel TJ; Jasper LE; Wu SJ
[Ad] Address:Naval Medical Research Center, Silver Spring, Maryland, USA subhamoy.pal.ctr@mail.mil....
[Ti] Title:Multicountry prospective clinical evaluation of two enzyme-linked immunosorbent assays and two rapid diagnostic tests for diagnosing dengue fever.
[So] Source:J Clin Microbiol;53(4):1092-102, 2015 Apr.
[Is] ISSN:1098-660X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We evaluated four dengue diagnostic devices from Alere, including the SD Bioline Dengue Duo (nonstructural [NS] 1 Ag and IgG/IgM), the Panbio Dengue Duo Cassette (IgM/IgG) rapid diagnostic tests (RDTs), and the Panbio dengue IgM and IgG capture enzyme-linked immunosorbent assays (ELISAs) in a prospective, controlled, multicenter study in Peru, Venezuela, Cambodia, and the United States, using samples from 1,021 febrile individuals. Archived, well-characterized samples from an additional 135 febrile individuals from Thailand were also used. Reference testing was performed on all samples using an algorithm involving virus isolation, in-house IgM and IgG capture ELISAs, and plaque reduction neutralization tests (PRNT) to determine the infection status of the individual. The primary endpoints were the clinical sensitivities and specificities of these devices. The SD Bioline Dengue Duo had an overall sensitivity of 87.3% (95% confidence interval [CI], 84.1 to 90.2%) and specificity of 86.8% (95% CI, 83.9 to 89.3%) during the first 14 days post-symptom onset (p.s.o.). The Panbio Dengue Duo Cassette demonstrated a sensitivity of 92.1% (87.8 to 95.2%) and specificity of 62.2% (54.5 to 69.5%) during days 4 to 14 p.s.o. The Panbio IgM capture ELISA had a sensitivity of 87.6% (82.7 to 91.4%) and specificity of 88.1% (82.2 to 92.6%) during days 4 to 14 p.s.o. Finally, the Panbio IgG capture ELISA had a sensitivity of 69.6% (62.1 to 76.4%) and a specificity of 88.4% (82.6 to 92.8%) during days 4 to 14 p.s.o. for identification of secondary dengue infections. This multicountry prospective study resulted in reliable real-world performance data that will facilitate data-driven laboratory test choices for managing patient care during dengue outbreaks.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Entry month:1503
[Cu] Class update date: 150509
[Lr] Last revision date:150509
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1128/JCM.03042-14


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