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[PMID]: 28343146
[Au] Autor:Menanteau-Ledouble S; Krauss I; Goncalves RA; Weber B; Santos GA; El-Matbouli M
[Ad] Address:Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria. Electronic address: Ledouble@vetmeduni.ac.at.
[Ti] Title:Antimicrobial effect of the Biotronic® Top3 supplement and efficacy in protecting rainbow trout (Oncorhynchus mykiss) from infection by Aeromonas salmonicida subsp. salmonicida.
[So] Source:Res Vet Sci;114:95-100, 2017 Oct.
[Is] ISSN:1532-2661
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Demand for more environmentally friendly practices have led to the adoption of several feed supplements by the fish farming industry. In the present study, we investigated a commercially available formula that includes a mixture of three compounds: organic acids, a phytochemical and Biomin® Permeabilizing Complex. This mixture demonstrated antimicrobial properties in vitro and was able to inhibit growth of multiple species of aquatic bacterial pathogens, including Aeromonas salmonicida. Bacterial challenge was performed using A. salmonicida and three exposure routes: intra-peritoneal injection, immersion, and cohabitation. Mortality rates following infection by injection were significantly decreased in the fish that had received the supplemented feed. Fish infected through the other routes did not show a significant difference in mortality. In term of farming performance, while the fish that had received the feed supplement showed an improvement in weight gain and final weight, these changes were not found to be statistically significant. Similarly, no significant difference was observed in the feed conversion ratio. The results of this study suggest that this feed supplement may be effective at protecting rainbow trout from fish furunculosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1703
[Cu] Class update date: 171024
[Lr] Last revision date:171024
[St] Status:In-Process

  2 / 1143 MEDLINE  
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[PMID]: 28622574
[Au] Autor:Veenstra KA; Wang T; Alnabulsi A; Douglas A; Russell KS; Tubbs L; Arous JB; Secombes CJ
[Ad] Address:Scottish Fish Immunology Research Centre, Institute of Biological and Environmental Sciences, University of Aberdeen, Tillydrone Avenue, Aberdeen, AB24 2TZ, UK. Electronic address: k.veenstra@abdn.ac.uk.
[Ti] Title:Analysis of adipose tissue immune gene expression after vaccination of rainbow trout with adjuvanted bacterins reveals an association with side effects.
[So] Source:Mol Immunol;88:89-98, 2017 Aug.
[Is] ISSN:1872-9142
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Most existing fish vaccines are presented in the form of oil-based emulsions delivered by intraperitoneal injection. Whilst very effective they are frequently associated with inflammatory responses that can result in clinically significant side-effects often involving the adipose tissue that is in direct contact with the vaccine. To explore the potential of immune gene expression changes in the adipose tissue of fish to be markers of vaccination efficacy or development of side-effects we have studied the response to a bacterial (Aeromonas salmonicida) vaccine administered with two different adjuvants. The first adjuvant was Montanide™ ISA 763A VG, thought to induce a mostly humoral response, and the second was Montanide™ ISA 761 VG that gives a more balanced humoral and cell mediated response. Following vaccination tissue samples were collected at days 3, 14 and 28 for RTqPCR analysis. Fifty immune genes were studied with a focus on a) pro-inflammatory associated molecules and b) adaptive immune response related molecules linked with possible Th1, Th2, Th17 and T-regulatory pathways, with the expression data analysed for associations with Speilberg post-vaccination side effect scores. The results showed that the adipose tissue is a particularly sensitive and discriminatory tissue for studying adjuvant effects. A clear upregulation of many immune genes occurred in response to both vaccine groups, which persisted over time and overlapped with the appearance of visible adhesions. Our analysis revealed a relationship between adipose tissue immune function and the development of vaccine-induced adhesions giving the potential to use immune gene expression profiling in this tissue to predict the side-effects seen.
[Mh] MeSH terms primary: Adipose Tissue/immunology
Adjuvants, Immunologic/pharmacology
Oncorhynchus mykiss/immunology
Vaccination/adverse effects
[Mh] MeSH terms secundary: Aeromonas salmonicida/immunology
Animals
Bacterial Vaccines/immunology
Fish Diseases/immunology
Fish Diseases/microbiology
Fish Diseases/prevention & control
Furunculosis/immunology
Furunculosis/microbiology
Furunculosis/prevention & control
Inflammation/immunology
Mannitol/analogs & derivatives
Mannitol/pharmacology
Oleic Acids/immunology
Oleic Acids/pharmacology
T-Lymphocytes, Regulatory/immunology
Th1 Cells/immunology
Th17 Cells/immunology
Th2 Cells/immunology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Adjuvants, Immunologic); 0 (Bacterial Vaccines); 0 (Oleic Acids); 3OWL53L36A (Mannitol)
[Em] Entry month:1710
[Cu] Class update date: 171009
[Lr] Last revision date:171009
[Js] Journal subset:IM
[Da] Date of entry for processing:170616
[St] Status:MEDLINE

  3 / 1143 MEDLINE  
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[PMID]: 28128084
[Au] Autor:Boer J; Mihajlovic D
[Ad] Address:Jurr Boer, MD, PhD, Department of Dermatology Deventer Hospital, Nico Bolkesteinlaan 75, 7416 SE Deventer, The Netherlands; jurrboer@home.nl; boerj@dz.nl.
[Ti] Title:Boils at Frictional Locations in a Patient with Hidradenitis Suppurativa.
[So] Source:Acta Dermatovenerol Croat;24(4):303-304, 2016 Dec.
[Is] ISSN:1847-6538
[Cp] Country of publication:Croatia
[La] Language:eng
[Ab] Abstract:Dear Editor, Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease. The primary clinical presentation are painful inflamed nodules or boils of inverse areas, i.e. the axillary and anogenito-crural regions, but it can also involve the infra- and inter-mammary regions (1,2). The etiology of HS is not clearly defined. Obesity, smoking, and genetic factors are considered important risk factors. In addition, it has also been suggested that friction may contribute to the development of HS, especially in the obese, but this is based on highly anecdotal reports (3-5). We describe a case with classic HS, obesity, and HS-like lesions at the position of the bra strap, suggesting that mechanical stress was an external pathogenic factor for HS development. A 33-year old woman presented with an 18-year history of chronic, recurrent, inflammatory nodules in the axillae, the groin, the pubic region, and to a lesser extent the abdomen and buttocks. She was obese with as result of 33.2 kg/m-2 of 33.2, had a positive family history of two first grade family members with HS, and was a smoker (19 Pack years). There were no other known comorbidities. The inflamed lesions had been treated with several courses of oral antibiotics (minocycline, erythromycin, and combination therapy of clindamycin and rifampicine) and surgical treatments: lancing, deroofing, and excisions (2,6). On examination, there were nodules, folliculitis, cysts, and depressed scars in the axillae and groins, including the inner thighs (Figure 1). On the chest, corresponding to where the lower edge of the patient's bra was usually located, a superficial nodule and follicular papules were observed, exactly coinciding with the red stripe caused by mechanical stress (friction and pressure) of the bra edge. There was no skin fold present on the location of the HS lesions, and there were no lesions observed in the intermammary region or on the side of the breasts in contact with the skin of the thorax (skin to skin contact) (Figure 2). Cultures from skin swabs showed commensal skin flora and moderate mixed anaerobic bacteria, as would be expected in a HS lesion. It is well documented that HS is a disease of the obese. However, the role of friction as an environmental factor is poorly documented. Patients report that environmental factors such as tight-fitting clothing or friction could cause flares in the disease (2). Furthermore, it has been postulated that friction may contribute to the development of HS by stimulating interfollicular hyperplasia (7). HS lesions arranged in a linear pattern suggest an environmental influence and suggests an etiopathogenic role for mechanical stress. Waistline, or as in this case the chest line, distribution indicates that wearing of tight waistbands, wide belts, or bras may induce HS in predisposed individuals. To our knowledge, there is only one case report describing an obese patient with classic HS (typical lesions in predilection areas) who developed HS like lesions on the upper abdomen (waist) at the height of the waistband as well as under the lower abdominal apron (skin on skin contact) (8). Two other reports suggesting a pathogenic role for mechanical stress are flawed, however, as neither of the cases showed signs of concomitant classic HS or had a family history, bringing into question the implied association of HS (9,10). In summary, we presented a case with classic HS locations (typical lesions on typical locations, i.e. the axillae and inguino-crural regions) developing inflammatory lesions on the chest at the location closely corresponding to where the bra strap was exerting mechanical pressure and friction on the skin. The lesions were clinically and microbiologically compatible with ectopic HS lesions. The chest is an atypical HS location free of apocrine sweat glands. It is postulated that these lesions may have been induced by mechanical stress, additionally triggered by the pro-inflammatory state of the obese body. Patients are encouraged to avoid friction from environmental factors such as tight clothing.
[Mh] MeSH terms primary: Furunculosis/etiology
Furunculosis/therapy
Hidradenitis Suppurativa/complications
[Mh] MeSH terms secundary: Adult
Anti-Bacterial Agents/therapeutic use
Axilla
Combined Modality Therapy
Debridement/methods
Drug Therapy, Combination
Female
Follow-Up Studies
Furunculosis/physiopathology
Groin
Hidradenitis Suppurativa/diagnosis
Humans
Obesity/complications
Obesity/diagnosis
Severity of Illness Index
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Bacterial Agents)
[Em] Entry month:1710
[Cu] Class update date: 171004
[Lr] Last revision date:171004
[Js] Journal subset:IM
[Da] Date of entry for processing:170127
[St] Status:MEDLINE

  4 / 1143 MEDLINE  
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[PMID]: 28703675
[Au] Autor:Tan RM; Ploog CL
[Ti] Title:Pathology in Practice. Trichofolliculoma (ruptured) and secondary pyogranulomatous furunculosis in a rock hyrax.
[So] Source:J Am Vet Med Assoc;251(3):299-301, 2017 08 01.
[Is] ISSN:1943-569X
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 171002
[Lr] Last revision date:171002
[St] Status:In-Process
[do] DOI:10.2460/javma.251.3.299

  5 / 1143 MEDLINE  
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[PMID]: 28765570
[Au] Autor:Vincent AT; Paquet VE; Bernatchez A; Tremblay DM; Moineau S; Charette SJ
[Ad] Address:Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Quebec City, QC, G1V 0A6, Canada.
[Ti] Title:Characterization and diversity of phages infecting Aeromonas salmonicida subsp. salmonicida.
[So] Source:Sci Rep;7(1):7054, 2017 Aug 01.
[Is] ISSN:2045-2322
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Phages infecting Aeromonas salmonicida subsp. salmonicida, the causative agent of the fish disease furunculosis, have been isolated for decades but very few of them have been characterized. Here, the host range of 12 virulent phages, including three isolated in the present study, was evaluated against a panel of 65 A. salmonicida isolates, including representatives of the psychrophilic subspecies salmonicida, smithia, masoucida, and the mesophilic subspecies pectinolytica. This bacterial set also included three isolates from India suspected of being members of a new subspecies. Our results allowed to elucidate a lytic dichotomy based on the lifestyle of A. salmonicida (mesophilic or psychrophilic) and more generally, on phage types (lysotypes) for the subspecies salmonicida. The genomic analyses of the 12 phages from this study with those available in GenBank led us to propose an A. salmonicida phage pan-virome. Our comparative genomic analyses also suggest that some phage genes were under positive selection and A. salmonicida phage genomes having a discrepancy in GC% compared to the host genome encode tRNA genes to likely overpass the bias in codon usage. Finally, we propose a new classification scheme for A. salmonicida phages.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170927
[Lr] Last revision date:170927
[St] Status:In-Data-Review
[do] DOI:10.1038/s41598-017-07401-7

  6 / 1143 MEDLINE  
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[PMID]: 28407501
[Au] Autor:Curtis LR; Bravo CF; Bayne CJ; Tilton F; Arkoosh MR; Lambertini E; Loge FJ; Collier TK; Meador JP; Tilton SC
[Ad] Address:Department of Environmental and Molecular Toxicology, Oregon State University, ALS 1007, Corvallis, OR 97331, USA.
[Ti] Title:Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons.
[So] Source:Ecotoxicol Environ Saf;142:157-163, 2017 Aug.
[Is] ISSN:1090-2414
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:We previously observed that exposure to a complex mixture of high molecular weight polycyclic aromatic hydrocarbons (PAHs) increased sensitivity of rainbow trout (Oncorhynchus mykiss) to subsequent challenge with Aeromonas salmonicida, the causative agent of furunculosis. In this study, we evaluate potential mechanisms associated with disease susceptibility from combined environmental factors of dietary PAH exposure and pathogen challenge. Rainbow trout were fed a mixture of ten high molecular weight PAHs at an environmentally relevant concentration (7.82µg PAH mixture/g fish/day) or control diet for 50 days. After 50 days of PAH exposure, fish were challenged with either Aeromonas salmonicida at a lethal concentration 30 (LC ) or growth media without the pathogen (mock challenge). Head kidneys were collected 2, 4, 10 and 20 days after challenge and gene expression (q<0.05) was evaluated among treatments. In animals fed the PAH contaminated diet, we observed down-regulation of expression for innate immune system genes in pathways (p<0.05) for the terminal steps of the complement cascade (complement component C6) and other bacteriolytic processes (lysozyme type II) potentially underlying increased disease susceptibility after pathogen challenge. Increased expression of genes associated with hemorrhage/tissue remodeling/inflammation pathways (p<0.05) was likely related to more severe head kidney damage due to infection in PAH-fed compared to control-fed fish. This study is the first to evaluate transcriptional signatures associated with the impact of chronic exposure to an environmentally relevant mixture of PAHs in disease susceptibility and immunity.
[Mh] MeSH terms primary: Aeromonas salmonicida/pathogenicity
Head Kidney/immunology
Immunity, Innate/drug effects
Oncorhynchus mykiss/microbiology
Polycyclic Aromatic Hydrocarbons/toxicity
Transcription, Genetic/drug effects
[Mh] MeSH terms secundary: Animals
Down-Regulation
Immunity, Innate/genetics
Muramidase/metabolism
Oncorhynchus mykiss/immunology
Oncorhynchus mykiss/metabolism
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Polycyclic Aromatic Hydrocarbons); EC 3.2.1.17 (Muramidase)
[Em] Entry month:1709
[Cu] Class update date: 170922
[Lr] Last revision date:170922
[Js] Journal subset:IM
[Da] Date of entry for processing:170413
[St] Status:MEDLINE

  7 / 1143 MEDLINE  
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[PMID]: 28372487
[Au] Autor:Brosnahan CL; Humphrey S; Knowles G; Ha HJ; Pande A; Jones JB
[Ad] Address:a Animal Health Laboratory , Ministry for Primary Industries , 66 Ward Street, Upper Hutt , New Zealand.
[Ti] Title:Nocardiosis in freshwater reared Chinook salmon (Oncorhynchus tshawytscha).
[So] Source:N Z Vet J;65(4):214-218, 2017 Jul.
[Is] ISSN:1176-0710
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:CASE HISTORY: An investigation was conducted to identify the cause of mortalities in freshwater reared Chinook salmon (Oncorhynchus tshawytscha). Mortalities occurred in juvenile salmon, at a salmon rearing facility in the South Island of New Zealand. The affected fish were from a pen inside the facility with no surrounding pens or other year classes affected. CLINICAL FINDINGS: Clinically affected fish presented with skin lesions. The majority of skin lesions were unruptured, boil-like, raised circular masses up to 4 cm in diameter, particularly on the dorsolateral aspects and the flank. A number of fish presented with large ulcers resulting from rupturing of the raised lesions described above. This clinical presentation showed similarities to that of furunculosis caused by typical Aeromonas salmonicida, a bacterium exotic to New Zealand. LABORATORY FINDINGS: Samples were taken from two representative fish in the field for histopathology, bacterial culture and molecular testing. Histopathological findings included granulomatous lesions in the kidney, liver, spleen and muscle. When stained with Fite-Faraco modified acid fast stain filamentous branching rods were identified within these granulomas. Following bacterial culture of kidney swabs pure growth of small white matt adherent colonies was observed. This isolate was identified as a Nocardia species by biochemical testing and nucleotide sequencing of the partial 16S rRNA gene. All samples were negative for A. salmonicida based on bacterial culture and PCR testing. DIAGNOSIS: Nocardiosis caused by a Nocardia species. CLINICAL RELEVANCE: Nocardiosis in these fish was caused by a previously undescribed Nocardia species that differs from the species known to be pathogenic to fish: N. asteroides, N. salmonicida and N. seriole. This bacterium is likely to be a new or unnamed environmental species of Nocardia that has the potential to cause disease in Chinook salmon under certain conditions. The clinical presentation of this Nocardia species manifested as raised, boil-like skin lesions which has similarities to the presentation of furunculosis caused by the bacterium typical A. salmonicida, a species exotic to New Zealand.
[Mh] MeSH terms primary: Fish Diseases/microbiology
Nocardia Infections/veterinary
Nocardia/isolation & purification
Salmon/microbiology
[Mh] MeSH terms secundary: Animals
Databases, Nucleic Acid
Fish Diseases/genetics
Fish Diseases/pathology
Fresh Water
Genes, rRNA
New Zealand
Nocardia/genetics
Nocardia Infections/genetics
Nocardia Infections/pathology
Polymerase Chain Reaction
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[Js] Journal subset:IM
[Da] Date of entry for processing:170404
[St] Status:MEDLINE
[do] DOI:10.1080/00480169.2017.1314794

  8 / 1143 MEDLINE  
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[PMID]: 28182704
[Au] Autor:Marana MH; Jørgensen LV; Skov J; Chettri JK; Holm Mattsson A; Dalsgaard I; Kania PW; Buchmann K
[Ad] Address:Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
[Ti] Title:Subunit vaccine candidates against Aeromonas salmonicida in rainbow trout Oncorhynchus mykiss.
[So] Source:PLoS One;12(2):e0171944, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Aeromonas salmonicida subsp. salmonicida is the etiological agent of furunculosis and a major fish health problem in salmonid aquaculture worldwide. Injection vaccination with commercial mineral oil-adjuvanted bacterin vaccines has been partly successful in preventing the disease but in Danish rainbow trout (Oncorhynchus mykiss, Walbaum) aquaculture furunculosis outbreaks still occur. In this study we tested the efficacy of experimental subunit vaccines against A. salmonicida infection in rainbow trout. We utilized in silico screening of the proteome of A. salmonicida subsp. salmonicida strain A449 and identified potential protective protein antigens that were tested by in vivo challenge trial. A total of 14 proteins were recombinantly expressed in Escherichia coli and prepared in 3 different subunit vaccine combinations to immunize 3 groups of rainbow trout by intraperitoneal (i.p.) injection. The fish were exposed to virulent A. salmonicida 7 weeks after immunization. To assess the efficacy of the subunit vaccines we evaluated the immune response in fish after immunization and challenge infection by measuring the antibody levels and monitoring the survival of fish in different groups. The survival of fish at 3 weeks after challenge infection showed that all 3 groups of fish immunized with 3 different protein combinations exhibited significantly lower mortalities (17-30%) compared to the control groups (48% and 56%). The ELISA results revealed significantly elevated antibody levels in fish against several protein antigens, which in some cases were positively correlated to the survival.
[Mh] MeSH terms primary: Aeromonas salmonicida/immunology
Fish Diseases/immunology
Gram-Negative Bacterial Infections/immunology
Oncorhynchus mykiss/immunology
Vaccines, Subunit/immunology
[Mh] MeSH terms secundary: Aeromonas salmonicida/pathogenicity
Animals
Antibodies, Bacterial/immunology
Bacterial Proteins/immunology
Fish Diseases/prevention & control
Gram-Negative Bacterial Infections/prevention & control
Immunization/methods
Oncorhynchus mykiss/microbiology
Proteome/immunology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Antibodies, Bacterial); 0 (Bacterial Proteins); 0 (Proteome); 0 (Vaccines, Subunit)
[Em] Entry month:1708
[Cu] Class update date: 170828
[Lr] Last revision date:170828
[Js] Journal subset:IM
[Da] Date of entry for processing:170209
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0171944

  9 / 1143 MEDLINE  
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[PMID]: 28124673
[Ti] Title:Answer to Photo Quiz: Fever and painful skin lesions after a holiday in Gambia.
[So] Source:Neth J Med;75(1):42, 2017 Jan.
[Is] ISSN:1872-9061
[Cp] Country of publication:Netherlands
[La] Language:eng
[Mh] MeSH terms primary: Cellulitis/diagnosis
Furunculosis/diagnosis
Myiasis/diagnosis
Skin Diseases/diagnosis
Travel
[Mh] MeSH terms secundary: Cellulitis/complications
Cellulitis/microbiology
Diagnosis, Differential
Fever/diagnosis
Fever/microbiology
Furunculosis/microbiology
Gambia
Headache/diagnosis
Headache/microbiology
Humans
Leg/microbiology
Male
Myiasis/complications
Myiasis/microbiology
Skin Diseases/microbiology
Young Adult
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170822
[Lr] Last revision date:170822
[Js] Journal subset:IM
[Da] Date of entry for processing:170126
[St] Status:MEDLINE

  10 / 1143 MEDLINE  
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[PMID]: 28533470
[Au] Autor:Padra JT; Sundh H; Sundell K; Venkatakrishnan V; Jin C; Samuelsson T; Karlsson NG; Lindén SK
[Ad] Address:Department of Medical Chemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden.
[Ti] Title:Aeromonas salmonicida Growth in Response to Atlantic Salmon Mucins Differs between Epithelial Sites, Is Governed by Sialylated and -Acetylhexosamine-Containing -Glycans, and Is Affected by Ca .
[So] Source:Infect Immun;85(8), 2017 Aug.
[Is] ISSN:1098-5522
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:causes furunculosis in salmonids and is a threat to Atlantic salmon aquaculture. The epithelial surfaces that the pathogen colonizes are covered by a mucus layer predominantly comprised of secreted mucins. By using mass spectrometry to identify mucin glycan structures with and without enzymatic removal of glycan residues, coupled to measurements of bacterial growth, we show here that the complex Atlantic salmon intestinal mucin glycans enhance growth, whereas the more simple skin mucin glycans do not. Of the glycan residues present terminally on the salmon mucins, only -acetylglucosamine (GlcNAc) enhances growth. Sialic acids, which have an abundance of 75% among terminal glycans from skin and of <50% among intestinal glycans, cannot be removed or used by for growth-enhancing purposes, and they shield internal GlcNAc from utilization. A Ca concentration above 0.1 mM is needed for to be able to utilize mucins for growth-promoting purposes, and 10 mM further enhances both growth in response to mucins and binding of the bacterium to mucins. In conclusion, GlcNAc and sialic acids are important determinants of the interaction with its host at the mucosal surface. Furthermore, since the mucin glycan repertoire affects pathogen growth, the glycan repertoire may be a factor to take into account during breeding and selection of strains for aquaculture.
[Mh] MeSH terms primary: Acetylglucosamine/metabolism
Aeromonas salmonicida/growth & development
Calcium/metabolism
Mucins/metabolism
Polysaccharides/chemistry
Salmo salar/metabolism
Sialic Acids/metabolism
[Mh] MeSH terms secundary: Aeromonas salmonicida/pathogenicity
Aeromonas salmonicida/physiology
Animals
Aquaculture
Furunculosis/microbiology
Glycosylation
Hexosamines/chemistry
Intestines/chemistry
Mass Spectrometry
Mucins/chemistry
Polysaccharides/metabolism
Skin/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Hexosamines); 0 (Mucins); 0 (Polysaccharides); 0 (Sialic Acids); SY7Q814VUP (Calcium); V956696549 (Acetylglucosamine)
[Em] Entry month:1708
[Cu] Class update date: 170807
[Lr] Last revision date:170807
[Js] Journal subset:IM
[Da] Date of entry for processing:170523
[St] Status:MEDLINE


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