Database : MEDLINE
Search on : Hemiplegia [Words]
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[PMID]: 25529342
[Au] Autor:Inoue Y; Honda S; Watanabe M; Ando Y
[Ad] Address:Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: yinoue@fc.kuh.kumamoto-u.ac.jp....
[Ti] Title:Educational campaigns at point of purchase in rural supermarkets improve stroke knowledge.
[So] Source:J Stroke Cerebrovasc Dis;24(2):480-4, 2015 Feb.
[Is] ISSN:1532-8511
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: The number of elderly people is dramatically increasing, and this trend is especially pronounced in rural populations. The aim of the present study was to verify the effectiveness of stroke education in a rural area. METHODS: The stroke educational flyers were distributed for 3 weeks at the point of purchase within supermarkets. Questionnaires were used to determine knowledge about stroke and appropriate emergent action on identifying stroke. RESULTS: A total of 882 people responded to the questionnaires before (n = 409) and 3 months after (n = 473) the campaign. Of these, 686 (77.8%) were aged 65 years or older. The percentages of correct answers for hemiplegia and one-sided numbness (P < .05 for both) and calling emergency medical services (EMS) on identifying stroke occurrence (P < .001) were higher after the campaign compared with those before the campaign. Of the respondents aged 65 years or older, the percentages of correct answers for numbness on one side and calling for EMS on identifying stroke were higher after the campaign (P < .05 and P < .001, respectively). CONCLUSIONS: A simple point-of-purchase stroke campaign using educational flyers could meaningfully affect stroke knowledge among elderly persons in a rural community.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1502
[Js] Journal subset:IM
[St] Status:In-Process

  2 / 11892 MEDLINE  
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[PMID]: 25759148
[Au] Autor:Tatla SK; Shirzad N; Lohse KR; Virji-Babul N; Hoens AM; Holsti L; Li LC; Miller KJ; Lam MY; Van der Loos HF
[Ad] Address:Sunny Hill Health Centre for Children, Vancouver, BC, Canada. statla2@cw.bc.ca.
[Ti] Title:Therapists' perceptions of social media and video game technologies in upper limb rehabilitation.
[So] Source:JMIR Serious Games;3(1):e2, 2015.
[Is] ISSN:2291-9279
[Cp] Country of publication:Canada
[La] Language:eng
[Ab] Abstract:BACKGROUND: The application of technologies, such as video gaming and social media for rehabilitation, is garnering interest in the medical field. However, little research has examined clinicians' perspectives regarding technology adoption by their clients. OBJECTIVE: The objective of our study was to explore therapists' perceptions of how young people and adults with hemiplegia use gaming and social media technologies in daily life and in rehabilitation, and to identify barriers to using these technologies in rehabilitation. METHODS: We conducted two focus groups comprised of ten occupational therapists/physiotherapists who provide neurorehabilitation to individuals with hemiplegia secondary to stroke or cerebral palsy. Data was analyzed using inductive thematic analysis. The diffusion of innovations theory provided a framework to interpret emerging themes. RESULTS: Therapists were using technology in a limited capacity. They identified barriers to using social media and gaming technology with their clients, including a lack of age appropriateness, privacy issues with social media, limited transfer of training, and a lack of accessibility of current systems. Therapists also questioned their role in the context of technology-based interventions. The opportunity for social interaction was perceived as a major benefit of integrated gaming and social media. CONCLUSIONS: This study reveals the complexities associated with adopting new technologies in clinical practice, including the need to consider both client and clinician factors. Despite reporting several challenges with applying gaming and social media technology with clinical populations, therapists identified opportunities for increased social interactions and were willing to help shape the development of an upper limb training system that could more readily meet the needs of clients with hemiplegia. By considering the needs of both therapists and clients, technology developers may increase the likelihood that clinicians will adopt innovative technologies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Da] Date of entry for processing:150311
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.2196/games.3401

  3 / 11892 MEDLINE  
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[PMID]: 25758081
[Au] Autor:Belhassen-Garcia M; Rábano-Gutiérrez A; Velasco-Tirado V; Romero-Alegria A; Pérez-Garcia ML; Martin-Oterino JA
[Ad] Address:Department of Internal Medicine, Unit of Infectious Diseases. IBSAL. University Hospital of Salamanca. CIETUS, University of Salamanca, Spain.
[Ti] Title:Atypical progressive multifocal leukoencephalopathy in a patient with antisynthetase syndrome.
[So] Source:Intern Med;54(5):519-24, 2015.
[Is] ISSN:1349-7235
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Antisynthetase syndrome is a disorder belonging to the dermatomyositis/polymyositis group, with high rates of morbidity and mortality. We herein present the case of a 71-year-old man who was diagnosed with antisynthetase syndrome and treated with rituximab. Almost three years later, the patient showed right-sided hemiparesis that ultimately progressed to complete hemiplegia and advancing cognitive deterioration with a poor clinical outcome. The neuropathological diagnosis was progressive multifocal leukoencephalopathy. Treatment with rituximab for antisynthetase syndrome itself plays a fundamental role in the development of infectious complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.2169/internalmedicine.54.2748

  4 / 11892 MEDLINE  
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[PMID]: 25731404
[Au] Autor:Yamamoto Y; Tanaka H; Maruyama T; Matsuzaki H; Natsume T; Miyazaki A; Satoh Y; Satsuka T; Yoshioka T; Kanada Y; Otsuka R; Yanagihara A; Yokoyama M; Kobayashi T
[Ad] Address:Dept. of Surgery, Funabashi Municipal Medical Center.
[Ti] Title:[Long-term survival of a patient with esophageal cancer with brain metastasis after multidisciplinary therapy - a case report].
[So] Source:Gan To Kagaku Ryoho;41(12):2006-9, 2014 Nov.
[Is] ISSN:0385-0684
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:A 70-year-old woman was admitted for difficulty in swallowing. Esophageal cancer (MtLt, type 3, T4N3M0, cStage IVa) was diagnosed in May 2010. The cancer was unresectable, and chemoradiotherapy (CRT) with TS-1 was initiated in June 2010, and a partial response (PR) was observed. After CRT, TS-1 was continued, but a brain metastasis was detected owing to the development of right hemiplegia in April 2012. Craniotomy and tumorectomy were performed, and the right hemiplegia improved. Pathological examination of the brain tumor indicated squamous cell carcinoma. Because of a recurrence of brain metastasis, a gamma knife procedure was performed in May 2012. Subsequently, several recurrences of brain metastases were diagnosed, and a total of 7 gamma knife procedures were performed up to January 2014. Although systemic chemotherapy (5-fluorouracil and cisplatin [FP], 5 courses)was administered, the patient showed progressive lung metastases in February 2013. The chemotherapy regimen was changed from FP to docetaxel (TXT), but the lung metastases continued to progress up to June 2013. The patient died in March 2014. Patients with esophageal cancer and metastases to the brain have poor prognosis, but the present patient survived approximately 2 years after first diagnosis of metastases to the brain after multidisciplinary therapy.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Process

  5 / 11892 MEDLINE  
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[PMID]: 25731371
[Au] Autor:Yoshitomi S; Tsuji H; Abe Y; Miyahara K; Kashima H; Kurosaki T; Kuroda M; Yamano T; Takagi S; Ikeda E; Hirai R; Moriyama S
[Ad] Address:Dept. of Surgery, Japanese Red Cross Okayama Hospital.
[Ti] Title:[Two cases of dural metastasis of breast cancer].
[So] Source:Gan To Kagaku Ryoho;41(12):1906-8, 2014 Nov.
[Is] ISSN:0385-0684
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:The first case of dural metastasis occurred in a 60s years old woman, who presented with bone metastasis to the right breast. Nine months later, disorientation and left hemiplegia developed, the right coronal bone metastasis enlarged, and dural metastases were detected close to the tumor, as observed by using cranial magnetic resonance imaging (MRI). Whole brain radiation and chemotherapy(weekly paclitaxel)were administered. The right coronal bone metastasis reduced remarkably, and the dural metastases almost disappeared, as observed on a cranial MRI scan. The second case of dural metastasis occurred in a 50s years old woman who presented with multiple bone metastases. Extensive bone metastases to the skull and dural metastases to the side of the head were observed on cranial MRI scans. Subsequently, the patient experienced a severe headache, and whole brain radiation and pharmacotherapy with anastrozole and trastuzumab were administered. Cranial MRI revealed that the skull bone metastasis reduced and the dural metastases almost disappeared. We report that radiotherapy and pharmacotherapy were effective in these 2 cases of dural metastases of breast cancer.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Process

  6 / 11892 MEDLINE  
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[PMID]: 25460223
[Au] Autor:Molina M; Kudlinski C; Guilbert J; Spruijt S; Steenbergen B; Jouen F
[Ad] Address:Laboratoire Psychologie des Actions Langagières et Motrices, Université de Caen, France. Electronic address: michele.molina@unicaen.fr....
[Ti] Title:Motor imagery for walking: a comparison between cerebral palsy adolescents with hemiplegia and diplegia.
[So] Source:Res Dev Disabil;37:95-101, 2015 Feb.
[Is] ISSN:1873-3379
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The goal of the study was to investigate whether motor imagery (MI) could be observed in cerebral palsy (CP) participants presenting a bilateral affected body side (diplegia) as it has been previously revealed in participants presenting a unilateral body affected sided (hemiplegia). MI capacity for walking was investigated in CP adolescents diagnosed with hemiplegia (n=10) or diplegia (n=10) and in adolescents with typical motor development (n=10). Participants were explicitly asked to imagine walking before and after actually walking toward a target located at 4 m and 8 m. Movement durations for executed and imagined trials were recorded. ANOVA and Pearson's correlation analyses revealed the existence of time invariance between executed and imagined movement durations for the control group and both groups of CP participants. However, results revealed that MI capacity in CP participants was observed for the short distance (4 m) but not for the long distance (8 m). Moreover, even for short distance, CP participants performed worse than typical adolescents. These results are discussed inline of recent researches suggesting that MI in CP participants may not depend on the side of the lesion.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1502
[Js] Journal subset:IM
[St] Status:In-Process

  7 / 11892 MEDLINE  
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[PMID]: 25278338
[Au] Autor:Mitchell LE; Ziviani J; Boyd RN
[Ad] Address:L.E. Mitchell, PhD, MHSt(ClinEpi), BPhty, Queensland Centre of Cerebral Palsy and Rehabilitation Research, Level 7, Block 6, Royal Brisbane and Women's Hospital, Herston, Queensland 4029, Australia. louise.mitchell@health.qld.gov.au.
[Ti] Title:Habitual physical activity of independently ambulant children and adolescents with cerebral palsy: are they doing enough?
[So] Source:Phys Ther;95(2):202-11, 2015 Feb.
[Is] ISSN:1538-6724
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Despite the health benefits of regular physical activity, children with cerebral palsy (CP) are thought to participate in reduced levels of physical activity. OBJECTIVE: The study objective was to assess physical activity and determine the proportion adhering to the recommended 60 minutes of moderate-to-vigorous physical activity (MVPA) daily in independently ambulant children and adolescents with unilateral CP. DESIGN: This was a cross-sectional study. METHOD: Children (N=102; 52 boys, 50 girls; mean age=11 years 3 months, SD=2 years 4 months) with spastic hemiplegia classified at Gross Motor Function Classification System (GMFCS) levels I (n=44) and II (n=58) recorded physical activity over 4 days using an accelerometer. Activity counts were converted to daily and hourly time spent inactive and in light physical activity or MVPA using uniaxial cutpoints (inactive: ≤100 vertical counts·min(-1), light: 101 to 2,295 vertical counts·min(-1), MVPA: ≥2,296 vertical counts·min(-1)) and recorded step counts. Differences between groups were examined using t tests. RESULTS: Of a potential 396 days, 341 days (86%) were recorded. The average wear time was 11:44 (SD=1:56) hours. On a typical day, participants recorded 438 (SD=234) counts·min(-1), took 7,541 (SD=3,894) steps, spent 8:36 (SD=1:09) hours inactive, spent 2:38 (SD=0:51) hours in light activity, and spent 0:44 (SD=0:26) hours in MVPA. Only 25% of participants met the recommended level of MVPA on at least one day. Physical activity was highest in boys (versus girls), in children (versus adolescents), and on weekdays (versus weekends). LIMITATIONS: Participants were limited to children with unilateral spasticity who were classified at GMFCS levels I and II. CONCLUSIONS: The majority of independently ambulant children with unilateral CP did not perform sufficient physical activity to meet public health recommendations.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1502
[Js] Journal subset:AIM; IM
[St] Status:In-Process
[do] DOI:10.2522/ptj.20140031

  8 / 11892 MEDLINE  
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[PMID]: 25643588
[Au] Autor:Balint B; Bhatia KP
[Ad] Address:Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, UK; Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
[Ti] Title:Isolated and combined dystonia syndromes - an update on new genes and their phenotypes.
[So] Source:Eur J Neurol;22(4):610-7, 2015 Apr.
[Is] ISSN:1468-1331
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Recent consensus on the definition, phenomenology and classification of dystonia centres around phenomenology and guides our diagnostic approach for the heterogeneous group of dystonias. Current terminology classifies conditions where dystonia is the sole motor feature (apart from tremor) as 'isolated dystonia', while 'combined dystonia' refers to dystonias with other accompanying movement disorders. This review highlights recent advances in the genetics of some isolated and combined dystonic syndromes. Some genes, such as ANO3, GNAL and CIZ1, have been discovered for isolated dystonia, but they are probably not a common cause of classic cervical dystonia. Conversely, the phenotype associated with TUBB4A mutations expanded from that of isolated dystonia to a syndrome of hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC syndrome). Similarly, ATP1A3 mutations cause a wide phenotypic spectrum ranging from rapid-onset dystonia-parkinsonism to alternating hemiplegia of childhood. Other entities entailing dystonia-parkinsonism include dopamine transporter deficiency syndrome (SLC63 mutations); dopa-responsive dystonias; young-onset parkinsonism (PARKIN, PINK1 and DJ-1 mutations); PRKRA mutations; and X-linked TAF1 mutations, which rarely can also manifest in women. Clinical and genetic heterogeneity also characterizes myoclonus-dystonia, which includes not only the classical phenotype associated with epsilon-sarcoglycan mutations but rarely also presentation of ANO3 gene mutations, TITF1 gene mutations typically underlying benign hereditary chorea, and some dopamine synthesis pathway conditions due to GCH1 and TH mutations. Thus, new genes are being recognized for isolated dystonia, and the phenotype of known genes is broadening and now involves different combined dystonia syndromes.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1111/ene.12650

  9 / 11892 MEDLINE  
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[PMID]: 25745309
[Au] Autor:Jaiswal A; Garg RK; Malhotra HS; Verma R; Singh MK
[Ad] Address:Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India....
[Ti] Title:Seizures in patients with cerebral hemiatrophy: A prognostic evaluation.
[So] Source:Ann Indian Acad Neurol;18(1):39-44, 2015 Jan-Mar.
[Is] ISSN:0972-2327
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:PURPOSE: Cerebral hemiatrophy is a common childhood disease. It clinically manifests with seizures, hemiparesis and mental retardation. MATERIALS AND METHODS: In this prospective study, previously untreated patients with seizures and cerebral hemiatrophy were recruited. Cerebral hemiatrophy was diagnosed on the basis of hemispheric ratio. Patients with acquired hemiconvulsion, hemiplegia, and epilepsy (HHE) syndrome were included in group A. Group B included patients with congenital HHE syndrome. Patients were followed up for 6 months for seizure recurrence. RESULTS: Out of 42 patients 26 were in group A and 16 were in group B. After 6 months, there was significant reduction in seizure frequency (P < 0.0001) in both the groups. At least 50% reduction in seizure frequency was noted in all the patients. Complete seizure freedom was observed in 15 (35.7%) patients. Seizure recurrences were significantly higher (P = 0.008) in group A. On univariate analysis, predictors of seizure recurrences were history of febrile seizures (P = 0.013), hippocampal sclerosis (P = 0.001), thalamic atrophy (P = 0.001), basal ganglia atrophy (P = 0.001), cerebellar atrophy (P = 0.01), ventricular dilatation (P = 0.001), epileptiform discharges at presentation (P = 0.023), complex partial seizures (P = 0.006) and status epilepticus (P = 0.02). On multivariate analysis, hemispheric ratio was the only significant factor for seizure recurrence. CONCLUSION: Patients with congenital hemiatrophy had better seizure control than that in patients with HHE syndrome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Cu] Class update date: 150309
[Lr] Last revision date:150309
[Da] Date of entry for processing:150306
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/0972-2327.144296

  10 / 11892 MEDLINE  
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[PMID]: 25722688
[Au] Autor:Xing Y; He J; Yu W; Hou L; Chen J
[Ad] Address:China-Japan Union Hospital, Jilin University, Changchun 130033, Jilin Province, China....
[Ti] Title:Increased expression of receptor for advanced glycation end-products worsens focal brain ischemia in diabetic rats.
[So] Source:Neural Regen Res;7(13):1000-5, 2012 May 5.
[Is] ISSN:1673-5374
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:A rat model of diabetes mellitus was induced by a high fat diet, followed by focal brain ischemia induced using the thread method after 0.5 month. Immunohistochemistry showed that expression of receptor for advanced glycation end-products was higher in the ischemic cortex of diabetic rats compared with non-diabetic rats with brain ischemia. Western blot assay revealed increased phosphorylated c-Jun N-terminal kinase expression, and unchanged phosphorylated extracellular signal-regulated protein kinase protein expression in the ischemic cortex of diabetic rats compared with non-diabetic rats with brain ischemia. Additionally, phosphorylated p38 mitogen-activated protein kinase protein was not detected in any rats in the two groups. Severity of limb hemiplegia was worse in diabetic rats with brain ischemia compared with ischemia alone rats. The results suggest that increased expression of receptor for advanced glycation end-products can further activate the c-Jun N-terminal kinase pathway in mitogen-activated protein kinase, thereby worsening brain injury associated with focal brain ischemia in diabetic rats.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1502
[Cu] Class update date: 150309
[Lr] Last revision date:150309
[Da] Date of entry for processing:150227
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3969/j.issn.1673-5374.2012.13.006


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