Database : MEDLINE
Search on : Hemiplegia [Words]
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[PMID]: 25197589
[Au] Autor:Lin C; Barrio GA; Hurwitz LM; Kranz PG
[Ad] Address:Department of Neurology, Duke University, Durham, NC 27710, USA....
[Ti] Title:Cerebral air embolism from angioinvasive cavitary aspergillosis.
[So] Source:Case Rep Neurol Med;2014:406106, 2014.
[Is] ISSN:2090-6668
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Background. Nontraumatic cerebral air embolism cases are rare. We report a case of an air embolism resulting in cerebral infarction related to angioinvasive cavitary aspergillosis. To our knowledge, there have been no previous reports associating these two conditions together. Case Presentation. A 32-year-old female was admitted for treatment of acute lymphoblastic leukemia (ALL). Her hospital course was complicated by pulmonary aspergillosis. On hospital day 55, she acutely developed severe global aphasia with right hemiplegia. A CT and CT-angiogram of her head and neck were obtained demonstrating intravascular air emboli within the left middle cerebral artery (MCA) branches. She was emergently taken for hyperbaric oxygen therapy (HBOT). Evaluation for origin of the air embolus revealed an air focus along the left lower pulmonary vein. Over the course of 48 hours, her symptoms significantly improved. Conclusion. This unique case details an immunocompromised patient with pulmonary aspergillosis cavitary lesions that invaded into a pulmonary vein and caused a cerebral air embolism. With cerebral air embolisms, the acute treatment option differs from the typical ischemic stroke pathway and the provider should consider emergent HBOT. This case highlights the importance of considering atypical causes of acute ischemic stroke.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Da] Date of entry for processing:140908
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1155/2014/406106

  2 / 11713 MEDLINE  
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[PMID]: 25195266
[Au] Autor:Tang F; Han D; Qu S; Liang J; Liu B; Huang Y
[Ti] Title:[Diagnosis and management of jugulare glomus tumor and carotid body tumor].
[So] Source:Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;28(9):612-7, 2014 May.
[Is] ISSN:1001-1781
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To investigate diagnosis method and treatment experience of jugulare glomus tumor (JGT) and carotid body tumor (CBT). METHOD: Retrospective analysis. Clinical materials from 4 patients at one genealogy with JGT and CBT were collected. The clinical features, radiological characteristics, surgical methods and prognosis were assessed. The proband suffered from left JGT and left CBT, her younger sister had right CBT as well as her younger female cousin had bilateral CBT and right JGT, her older male cousin had bilateral CBT and left JGT. These JGT and CBT in four patients were resected under general anesthesia after preoperative ultrasound, CT or CT angiography (CTA), MRI, and digital subtraction angiography (DSA) examination as well as preoperative vascular embolization. RESULT: The surgery was uneventful in four cases, and there was no hemiplegia or deaths. All patients were followed up for 2 years to 29 months without recurrence. Six months after operation, the hoarseness also disappeared in the older male cousins but did not improve significantly in younger female cousin. The younger female cousin get right peripheral facial paralysis 1 year after surgery and her temporal bone CT indicated a right JGT. CONCLUSION: It is very important to assess JGT and CBT by Ultrasound, CT, CTA, MRI and DSA. Surgical resection is the first optional treatment for JGT and CBT. Blood loss can be reduced by preop erative vascular embolization. Serious complications could be avoid by operating under microscope, which can supply a clear surgical field and make the surgeon to protect the large blood vessels and nerve.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Process

  3 / 11713 MEDLINE  
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[PMID]: 24995688
[Au] Autor:Ferrari A; Maoret AR; Muzzini S; Alboresi S; Lombardi F; Sgandurra G; Paolicelli PB; Sicola E; Cioni G
[Ad] Address:Department of Biomedical, Metabolic Sciences and Neuroscience, University of Modena and Reggio Emilia, 42123 Reggio Emilia, Italy; Children Rehabilitation Unit, IRCCS S. Maria Nuova Hospital, 42123 Reggio Emilia, Italy. Electronic address: ferrari.adriano@asmn.re.it....
[Ti] Title:A randomized trial of upper limb botulimun toxin versus placebo injection, combined with physiotherapy, in children with hemiplegia.
[So] Source:Res Dev Disabil;35(10):2505-13, 2014 Oct.
[Is] ISSN:1873-3379
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The main goal of this study was to investigate the efficacy of Botulinum Toxin A (BoNT-A), combined with an individualized intensive physiotherapy/orthoses treatment, in improving upper limb activity and competence in daily activity in children with hemiplegia, and to compare its effectiveness with that of non-pharmacological instruments. It was a Randomized Clinical Trial of 27 children with spastic hemiplegic cerebral palsy, outpatients of two high speciality Centres for child rehabilitation. Each child was assigned by simple randomization to experimental group (BoNT-A) or control group (placebo). Assisting Hand Assessment (AHA) was chosen as primary outcome measure; other measures were selected according to ICF dimensions. Participants were assessed at baseline (T0), at T1, T2, T3 (1-3-6 months after injection, respectively). Every patient was given a specific physiotherapeutic treatment, consisting of individualized goal directed exercises, task oriented activities, daily stretching manoeuvres, functional and/or static orthoses. BoNT-A group showed a significant increase of AHA raw scores at T2, compared to control group (T2-T0: p=.025) and functional goals achievement (GAS) was also slightly better in the same group (p=.033). Other measures indicated some improvement in both groups, without significant intergroup differences. Children with intermediate severity of hand function at House scale for upper limb impairment seem to have a better benefit from BoNT-A protocol. BoNT-A was effective in improving manipulation in the activity domain, in association with individualized goal-directed physiotherapy and orthoses; the combined treatment is recommended. The study brings more evidence for the efficacy of a combined treatment botulinum toxin injection-physiotherapy-orthoses, and it gives some suggestions for candidate selection and individualized treatment.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Process

  4 / 11713 MEDLINE  
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[PMID]: 24928127
[Au] Autor:Pelzer N; de Vries B; Kamphorst JT; Vijfhuizen LS; Ferrari MD; Haan J; van den Maagdenberg AM; Terwindt GM
[Ad] Address:From Leiden University Medical Center (N.P., B.d.V., J.T.K., L.S.V., M.D.F., J.H., A.M.J.M.v.d.M., G.M.T.); and Rijnland Hospital (J.H.), Leiderdorp, the Netherlands....
[Ti] Title:PRRT2 and hemiplegic migraine: a complex association.
[So] Source:Neurology;83(3):288-90, 2014 Jul 15.
[Is] ISSN:1526-632X
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Hemiplegia/genetics
Membrane Proteins/genetics
Migraine Disorders/genetics
Nerve Tissue Proteins/genetics
[Mh] MeSH terms secundary: Arginine/genetics
Glutamine/genetics
Humans
Pedigree
Phenotype
Sodium-Potassium-Exchanging ATPase/genetics
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Membrane Proteins); 0 (Nerve Tissue Proteins); 0 (PRRT2 protein, human); 0RH81L854J (Glutamine); 94ZLA3W45F (Arginine); EC 3.6.1.- (ATP1A2 protein, human); EC 3.6.3.9 (Sodium-Potassium-Exchanging ATPase)
[Em] Entry month:1409
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:140715
[St] Status:MEDLINE
[do] DOI:10.1212/WNL.0000000000000590

  5 / 11713 MEDLINE  
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[PMID]: 24928122
[Au] Autor:Jen JC
[Ad] Address:From UCLA Neurology, Los Angeles, CA.
[Ti] Title:Comment: challenges in defining the clinical spectrum of neurogenetic disorders.
[So] Source:Neurology;83(3):290, 2014 Jul 15.
[Is] ISSN:1526-632X
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Hemiplegia/genetics
Membrane Proteins/genetics
Migraine Disorders/genetics
Nerve Tissue Proteins/genetics
[Mh] MeSH terms secundary: Humans
[Pt] Publication type:COMMENT; JOURNAL ARTICLE
[Nm] Name of substance:0 (Membrane Proteins); 0 (Nerve Tissue Proteins); 0 (PRRT2 protein, human)
[Em] Entry month:1409
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:140715
[St] Status:MEDLINE
[do] DOI:10.1212/WNL.0000000000000603

  6 / 11713 MEDLINE  
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[PMID]: 25192505
[Au] Autor:Olson HE; Poduri A; Pearl PL
[Ad] Address:Division of Epilepsy, Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.
[Ti] Title:Genetic forms of epilepsies and other paroxysmal disorders.
[So] Source:Semin Neurol;34(3):266-79, 2014 Jul.
[Is] ISSN:1098-9021
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Genetic mechanisms explain the pathophysiology of many forms of epilepsy and other paroxysmal disorders, such as alternating hemiplegia of childhood, familial hemiplegic migraine, and paroxysmal dyskinesias. Epilepsy is a key feature of well-defined genetic syndromes including tuberous sclerosis complex, Rett syndrome, Angelman syndrome, and others. There is an increasing number of single-gene causes or susceptibility factors associated with several epilepsy syndromes, including the early-onset epileptic encephalopathies, benign neonatal/infantile seizures, progressive myoclonus epilepsies, genetic generalized and benign focal epilepsies, epileptic aphasias, and familial focal epilepsies. Molecular mechanisms are diverse, and a single gene can be associated with a broad range of phenotypes. Additional features, such as dysmorphisms, head size, movement disorders, and family history may provide clues to a genetic diagnosis. Genetic testing can impact medical care and counseling. We discuss genetic mechanisms of epilepsy and other paroxysmal disorders, tools and indications for genetic testing, known genotype-phenotype associations, the importance of genetic counseling, and a look toward the future of epilepsy genetics.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1055/s-0034-1386765

  7 / 11713 MEDLINE  
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[PMID]: 24990007
[Au] Autor:Amichai T; Katz-Leurer M
[Ad] Address:Sackler Faculty of Medicine, School of Health Professions, Physical Therapy Department, Tel-Aviv University, Tel-Aviv, Israel.
[Ti] Title:Heart rate variability in children with cerebral palsy: Review of the literature and meta-analysis.
[So] Source:NeuroRehabilitation;35(1):113-22, 2014 Jan 1.
[Is] ISSN:1878-6448
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVE: A systematic review which aims to assess the evidence regarding the function of the autonomic heart rate regulation system among children with cerebral palsy (CP). METHODS: The target population included children with CP of diverse severity, aged 1.5 to 18 years. Databases searched for English language studies from 1960 to 2013: PubMed, EMBASE, CINAHL, Cochrane Library, The Physiotherapy Evidence Database (PEDro), and ClinicalTrials.gov site. Search terms included 'cerebral palsy' or 'spastic diplegia' or 'hemiplegia' or 'quadriplegia' and 'autonomic nervous system' or 'heart rate variability' or 'sympathetic' or 'para sympathetic'. Twenty five articles were identified and included if (1) participants were less than 18 years of age, (2) diagnosis of CP was made after the age of 18 months (3) more than 80% of cases had a diagnosis of CP and (4) autonomic cardiac heart rate regulation system state or response to a stimuli was described for all the participants. Six articles met the criteria for inclusion. RESULTS: Evidence suggests that reduced Heart Rate Variability (HRV) time domain parameters close to birth are associated with a CP diagnosis at the age of three years. In addition, HRV parameters' mean values, are significantly lower among children with CP compared to typically developed (TD) control. While performing head up, tilt or standing position, HRV was significantly reduced only among TD control, but no effect was seen in those variables among children with CP. CONCLUSION: Further studies are needed to assess the potential to predict CP by assessing HRV parameters among newborn children. In addition, assessing HRV among children with CP may improve our understanding of the heart rate autonomic system and its response to different stimulus such as muscle contraction, paced breathing and aerobic training.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3233/NRE-141097

  8 / 11713 MEDLINE  
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[PMID]: 24392811
[Au] Autor:Mahayana IT; Sari DC; Chen CY; Juan CH; Muggleton NG
[Ad] Address:1Institute of Cognitive Neuroscience, National Central University , Jhongli , Taiwan.
[Ti] Title:The potential of transcranial magnetic stimulation for population-based application: a region-based illustrated brief overview.
[So] Source:Int J Neurosci;124(10):717-23, 2014 Oct.
[Is] ISSN:1563-5279
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The awareness of the global trends in neuroscience study, especially in the cognitive neuroscience field, should be increased. One notable approach is the use of transcranial magnetic stimulation (TMS) not only as a research tool but also as a choice for treatment and rehabilitation in neurological disorders, such as post-stroke hemiplegia, visuospatial neglect syndrome, Alzheimer's disease (AD) and psychiatric conditions such as major depression and schizophrenia. All of these occur in significant numbers in highly populated regions. This paper briefly discusses the basic protocols and potential benefits of using TMS with the aim of providing insight that is useful in the design of future public health strategies in highly populated regions with a large neurocognitive burden of disease where this technique is currently underemployed.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3109/00207454.2013.872641

  9 / 11713 MEDLINE  
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[PMID]: 25098053
[Au] Autor:Masood CT; Hussain M; Anis-ur-Rehman; Abbasi S
[Ti] Title:Clinical presentation, risk factors and outcome of stroke at a district level teaching hospital.
[So] Source:J Ayub Med Coll Abbottabad;25(1-2):49-51, 2013 Jan-Jun.
[Is] ISSN:1025-9589
[Cp] Country of publication:Pakistan
[La] Language:eng
[Ab] Abstract:BACKGROUND: Stroke is a fatal clinical syndrome with mortality rate ranging up to 25%. Hypertension, smoking and diabetes mellitus are common preventable risk factors which are associated with serious outcome. Objective of this study was to determine the clinical presentation, risk factors and outcome of stroke. METHODS: A cross-sectional study was conducted in the Medical Wards of DHQ Teaching Hospital, Mirpur Azad Kashmir from March 2010 to January 2011. A questionnaire was prepared in accordance with the objectives of the study. Frequency of risk factors in patients with stroke were studied. Different clinical features were also noted and response to the given treatment was checked in the form of mortality and recovery. Frequencies and percentages were calculated using SPSS-12. RESULTS: Two hundred patients with stroke were selected. Of the total, 136 (68%) had hypertension, 55 (27.5%) were smokers, 53 (26.5%) had diabetes and 25 (12.5%) patients had ischemic heart disease. One hundred and two (51%) patients presented with headache, 99 (49.5%) developed hemiplegia and 94 (47%) had loss of consciousness. CT brain showed infarction in 144 (72%) patients while 56 (28%) had haemorrhage. Observed mortality in this study was 18 (9%) while 182 (91%) patients were discharged after treatment. CONCLUSION: Hypertension, smoking and diabetes mellitus are major modifiable risk factors for stroke. Headache, hemiplegia and loss of consciousness are major clinical features. Ischemic stroke is much common compared to hemorrhagic stroke. With proper care stroke is manageable satisfactorily.
[Mh] MeSH terms primary: Stroke/diagnosis
Stroke/epidemiology
[Mh] MeSH terms secundary: Aged
Cross-Sectional Studies
Diabetes Mellitus/epidemiology
Female
Headache/etiology
Hemiplegia/etiology
Hospitals, District
Hospitals, Teaching
Humans
Hypertension/epidemiology
Male
Middle Aged
Pakistan/epidemiology
Risk Factors
Smoking/epidemiology
Unconsciousness/etiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[Da] Date of entry for processing:140807
[St] Status:MEDLINE

  10 / 11713 MEDLINE  
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[PMID]: 25087281
[Au] Autor:Schmülling L
[Ti] Title:Der Umgang mit Angehörigen kann schwierig sein. Doch in der Regel gibt es auch für unverständliches Handeln gute Gründe. Die Sonderrolle. [Dealing with family can be difficult. However, as a rule there can also be good reasons for incomprehensible treatment. The special case].
[So] Source:Pflege Z;67(7):416-8, 2014 Jul.
[Is] ISSN:0945-1129
[Cp] Country of publication:Germany
[La] Language:ger
[Mh] MeSH terms primary: Caregivers/psychology
Nurse-Patient Relations
Professional-Family Relations
[Mh] MeSH terms secundary: Adaptation, Psychological
Consumer Satisfaction
Cooperative Behavior
Hemiplegia/nursing
Hemiplegia/psychology
Humans
Interdisciplinary Communication
Male
Middle Aged
Problem Solving
Social Support
Stress, Psychological/complications
Stress, Psychological/psychology
Stroke/nursing
Stroke/psychology
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:N
[Da] Date of entry for processing:140804
[St] Status:MEDLINE


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