Database : MEDLINE
Search on : Hemiplegia [Words]
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[PMID]: 26698408
[Au] Autor:Kuo HC; Gordon AM; Henrionnet A; Hautfenne S; Friel KM; Bleyenheuft Y
[Ad] Address:Department of Biobehavioral Sciences, Teachers College, Columbia University, 525 West 120th Street, Box 93, New York, NY 10027, USA. Electronic address: hk2455@tc.columbia.edu....
[Ti] Title:The effects of intensive bimanual training with and without tactile training on tactile function in children with unilateral spastic cerebral palsy: A pilot study.
[So] Source:Res Dev Disabil;49-50:129-39, 2016 Feb-Mar.
[Is] ISSN:1873-3379
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Children with unilateral spastic cerebral palsy (USCP) often have tactile impairments. Intensive bimanual training improves the motor abilities, but the effects on the sensory system have not been studied. Here we compare the effects of bimanual training with and without tactile training on tactile impairments. Twenty children with USCP (6-15.5 years; MACS: I-III) were randomized to receive either bimanual therapy (HABIT) or HABIT+tactile training (HABIT+T). All participants received 82h of standardized HABIT. In addition 8 sessions of 1h were provided to both groups. The HABIT+T group received tactile training (without vision) using materials of varied shapes and textures. The HABIT group received training with the same materials without tactile directed training (full vision). Primary outcomes included grating orientation task/GOT and stereognosis. Secondary outcomes included two-point discrimination/TPD, Semmes-Weinstein monofilaments/SWM. The GOT improved in both groups after training, while stereognosis of the more-affected hand tended to improve (but p=0.063). No changes were found in the TPD and the SWM. There were no group×test interactions for any measure. We conclude tactile spatial resolution can improve after bimanual training. Either intensive bimanual training alone or incorporation of materials with a diversity of shapes/textures may drive these changes.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1601
[Cu] Class update date: 160513
[Lr] Last revision date:160513
[Js] Journal subset:IM
[St] Status:In-Data-Review

  2 / 12343 MEDLINE  
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[PMID]: 27169454
[Au] Autor:Kawakami K; Ito R; Kageyama Y; Nagaharu K; Yamaguchi T; Ito N
[Ad] Address:Division of Hematology and Oncology, Suzuka General Hospital.
[Ti] Title:Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22).
[So] Source:Rinsho Ketsueki;57(4):477-82, 2016 Apr.
[Is] ISSN:0485-1439
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Superior sagittal sinus thrombosis (SSST) is a very rare but life-threatening complication in leukemia patients. SSST is very rare in acute myeloid leukemia (AML). In leukemia patients, several risk factors for SSST have been reported such as administration of L-asparaginase, disseminated intravascular coagulation, congenital thrombophilia, meningeal leukemia, and intrathecal chemotherapy (IT). Lumbar puncture itself and corticosteroid administration have also been acknowledged as risk factors. We describe herein our clinical experience with SSST in a 29-year-old Japanese man suffering from AML with t(8;21)(q22;q22), who presented with abrupt onset of loss of consciousness, left hemiplegia, and seizure soon after IT and high-dose cytarabine (HD-AraC) with dexamethasone for post remission consolidation. Despite the presence of intracranial hemorrhage (ICH) due to SSST rupture, we conducted anticoagulant therapy with heparin. Although ICH worsened temporarily, his clinical condition gradually improved with resolution of the SSST, and he eventually became fully ambulatory. There were no deficiencies of natural anticoagulants. Three additional cycles of HD-AraC without IT therapy were conducted, but no neurological complications recurred with the concomitant use of warfarin. He was discharged free of neurological deficits. In our case, there is a possibility that IT and the administration of corticosteroids along with HD-AraC triggered SSST.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.11406/rinketsu.57.477

  3 / 12343 MEDLINE  
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[PMID]: 26760482
[Au] Autor:Ibe Y; Tosaka M; Horiguchi K; Sugawara K; Miyagishima T; Hirato M; Yoshimoto Y
[Ad] Address:a Department of Neurosurgery , Gunma University Graduate School of Medicine , Maebashi , Japan....
[Ti] Title:Resection extent of the supplementary motor area and post-operative neurological deficits in glioma surgery.
[So] Source:Br J Neurosurg;30(3):323-9, 2016 Jun.
[Is] ISSN:1360-046X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Objective The supplementary motor area (SMA) is important for the prediction of post-operative symptoms after surgical resection of gliomas. We investigated the relationships between clinical factors and the resection range of SMA gliomas, and the post-operative neurological symptoms. Methods We retrospectively studied 18 consecutive surgeries for gliomas involving the SMA proper performed in 13 patients. Seven cases were recurrence of the tumour. Clinical factors and details of specific resection of the SMA proper (resection of posterior part, medial wall) and cingulate motor area (CMA) were examined. Results Eight cases suffered new post-operative neurological deficits. Six of these eight cases had transient deficits. Permanent deficits persisted in two cases with partial weakness or paresis, after rapid improvement of post-operative global weakness or hemiplegia, respectively. The risk of post-operative neurological deficits was not associated with the resection of the posterior part of the SMA proper or the CMA, but was associated with resection of the medial wall of the SMA proper. Surgery for recurrent tumour was associated with post-operative neurological deficits. The medial wall was frequently resected in recurrent cases. Discussion The frequency of post-operative neurological symptoms, including SMA syndrome, may be higher after resection of the medial wall of the SMA proper compared with the resection of only the lateral surface of the SMA proper.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3109/02688697.2015.1133803

  4 / 12343 MEDLINE  
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[PMID]: 27158569
[Au] Autor:Khubaib MU; Rathore FA; Waqas A; Jan MM; Sohail S
[Ad] Address:Department of Rehabilitation Medicine, CMH Lahore Medical College and Institute of Dentistry....
[Ti] Title:Knowledge Regarding Basic Facts of Stroke Among Final Year MBBS Students and House Officers: A Cross-Sectional Survey of 708 Respondents from Pakistan.
[So] Source:Cureus;8(3):e539, 2016.
[Is] ISSN:2168-8184
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Stroke is the leading cause of neurological disability in the world. In Pakistan, house officers (HOs) are usually the first contact for a stroke patient in the emergency department. Sometimes they need to make quick decisions regarding diagnosis and management without specialist supervision. Thousands of current final year MBBS (Bachelor of Medicine, Bachelor of Surgery) students will be performing the duties of HOs soon. This study documents the knowledge and confidence levels of final year students and HOs in Pakistan regarding basic facts related to initial diagnosis and management of stroke. MATERIALS AND METHODS: A questionnaire was developed using two standard textbooks of medicine and current stroke guidelines of the American Heart Association. The pre-tested self-administered questionnaire was distributed among 800 final year MBBS students and HOs in 14 medical colleges and hospitals in four different cities. The response rate was 88.5%. Data analysis was done using SPSS V.21. The CMH Lahore Medical College Ethics Review Committee approved this project. RESULTS: Respondents included medical students (n=496) and HOs (N= 212); most were female (n = 452, 63.9%). Of these, 31.4% had managed or assisted in the management of a patient with a stroke and had a higher confidence level in its diagnosis (p< 0.001) and management (p <0.001). Having a family member with stroke was associated with higher confidence in the diagnosis of stroke (p < 0.05) but not with confidence in its management (p = 0.41). Most correctly defined stroke (60.6%), identified the CT scan as the initial diagnostic modality (88.1%), knew the dosage of aspirin (64.9%), knew the time limit for thrombolysis (67.4%), and were familiar with the risk of deep vein thrombosis in immobilized stroke patients (85.4%). Less than half (44.5%) chose tissue plasminogen activator (t-PA) as the preferred initial intervention for acute ischemic stroke. CONCLUSION: This multicenter survey shows that the knowledge and confidence of medical students and HOs in Pakistan regarding initial diagnosis and management of stroke are inadequate in most domains. There is a need to improve the medical training for stroke in emergency departments for optimal outcomes. Public education campaigns about stroke should be conducted to increase the general awareness of the population about the prevention, signs, symptoms, and emergency steps to be taken when encountering a case of stroke.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Cu] Class update date: 160511
[Lr] Last revision date:160511
[Da] Date of entry for processing:160509
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.7759/cureus.539

  5 / 12343 MEDLINE  
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[PMID]: 26306931
[Au] Autor:Amelot A; Baronnet-Chauvet F; Fioretti E; Mathon B; Cornu P; Nouet A; Chauvet D
[Ad] Address:Department of Neurosurgery, Hôpital La Pitié Salpétrière, APHP, Paris, France aymmed@hotmail.fr....
[Ti] Title:Glioblastoma complicated by fatal malignant acute ischemic stroke: MRI finding to assist in tricky surgical decision.
[So] Source:Neuroradiol J;28(5):483-7, 2015 Oct.
[Is] ISSN:1971-4009
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: In most cases, glioblastomas are associated with seizures, headaches, neurological deficits, aphasia, or bleeding. But these tumors are rarely associated with cerebral infarction and never so deadly. CASE REPORT: A 40-year-old man presented with sudden morning isolated aphasia. One hour later, he developed a motor deficit at right upper member, quickly completed with a total right hemiplegia. Imaging studies revealed a left frontotemporal enhancing glioblastoma with a perilesional edema which produced an important mass effect on the posterior arm of the external capsule, on the primary motor cortex posteriorly and the entire sylvian valley anteriorly. Due to major surgical risks associated with left middle cerebral artery (MCA) inclusion and large edema, we decided to postpone the tumor removal and introduce quickly high concentrations of steroids. Twenty-four hours after his admittance, the patient presented a sudden impaired consciousness, coma, and a left mydriasis. A brain magnetic resonance image (MRI) revealed a left malignant MCA infarction, deadly for the patient. CONCLUSION: To our knowledge, glioblastomas complicated by fatal ischemic stroke have not been reported. We discuss the pathology of such an event and try to figure out if it was predictable based on MRI finding, and inevitable with precocious surgery.
[Mh] MeSH terms primary: Brain Neoplasms/complications
Glioblastoma/complications
Infarction, Middle Cerebral Artery/etiology
Magnetic Resonance Imaging
Stroke/etiology
[Mh] MeSH terms secundary: Adult
Decision Making
Fatal Outcome
Humans
Male
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1601
[Cu] Class update date: 160511
[Lr] Last revision date:160511
[Js] Journal subset:IM
[Da] Date of entry for processing:151104
[St] Status:MEDLINE
[do] DOI:10.1177/1971400915598073

  6 / 12343 MEDLINE  
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[PMID]: 27146299
[Au] Autor:Ju J; Hirose S; Shi XY; Ishii A; Hu LY; Zou LP
[Ad] Address:Department of Pediatrics, Chinese PLA General Hospital, Beijing, 100853, China....
[Ti] Title:Treatment with Oral ATP decreases alternating hemiplegia of childhood with de novo ATP1A3 Mutation.
[So] Source:Orphanet J Rare Dis;11(1):55, 2016.
[Is] ISSN:1750-1172
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Alternating hemiplegia of childhood is an intractable neurological disorder characterized by recurrent episodes of alternating hemiplegia accompanied by other paroxysmal symptoms. Recent research has identified mutations in the ATP1A3 gene as the underlying cause. Adenosine-5'-triphosphate has a vasodilatory effect, can enhance muscle strength and physical performance, and was hypothesized to improve the symptoms of paroxysmal hemiplegia. METHODS: A 7-year-old boy with alternating hemiplegia of childhood who was positive for a de novo ATP1A3 mutation was treated with adenosine- 5'- triphosphate supplementation orally as an innovative therapy for 2 years. Outcome was evaluated through the follow-up of improvement of hemiplegic episodes and psychomotor development. Side effects and safety were monitored in regularity. RESULTS: With the dosage of adenosine-5'-triphosphate administration increased, the patient showed significantly less frequency and shorter duration of hemiplegic episodes. Treatment with adenosine-5'-triphosphate was correlated with a marked amelioration of alternating hemiplegia of childhood episodes, and psychomotor development has improved. The maximum dose of oral administration of adenosine-5'-triphosphate reached 25 mg/kg per day. Adenosine-5'-triphosphate therapy was well tolerated without complaint of discomfort and side effects. CONCLUSIONS: The 2-year follow-up outcome of adenosine-5'-triphosphate therapy for alternating hemiplegia of childhood was successful.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Cu] Class update date: 160507
[Lr] Last revision date:160507
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1186/s13023-016-0438-7

  7 / 12343 MEDLINE  
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[PMID]: 26711920
[Au] Autor:Morita K; Fukuzawa H; Maeda K
[Ad] Address:Department of Pediatric surgery, Kobe Children's Hospital, Kobe, Japan.
[Ti] Title:Brain abscess in hepatopulmonary syndrome associated with biliary atresia.
[So] Source:Pediatr Int;57(6):1187-9, 2015 Dec.
[Is] ISSN:1442-200X
[Cp] Country of publication:Australia
[La] Language:eng
[Ab] Abstract:The first-choice therapy for biliary atresia (BA) is Kasai hepatoportoenterostomy, which has been shown to greatly improve outcome. Various long-term complications, however, such as portal hypertension and hepatopulmonary syndrome (HPS), can occur in patients with native liver. A rare case of brain abscess in an 11-year-old girl with HPS associated with BA is reported. The patient underwent hepatoportoenterostomy for BA at 53 days of age, with resolution of hyperbilirubinemia. At 10 years of age, she was diagnosed with severe HPS with right-to-left shunting, and preparations for liver transplantation proceeded. Three months after the diagnosis, she had a right parietal brain abscess. Given that the brain abscess enlarged in size, surgical drainage of the brain abscess was performed. The postoperative course was uneventful, but a slight left hemiplegia remained at discharge. The presumed mechanism of abscess formation in HPS may be right-to-left bacterial transit through intrapulmonary vascular dilatations and/or arteriovenous fistulae.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1512
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1111/ped.12711

  8 / 12343 MEDLINE  
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[PMID]: 25851322
[Au] Autor:Wilson BD; Morshedzadeh JH
[Ad] Address:Division of Cardiovascular Medicine, University of Utah, 30 North 1900 East, Room 4A100, Salt Lake City, UT 84132, USA brent.wilson@hsc.utah.edu.
[Ti] Title:Atrioesophageal fistula and pneumocephalus after pulmonary vein isolation.
[So] Source:Eur Heart J Cardiovasc Imaging;16(7):819, 2015 Jul.
[Is] ISSN:2047-2412
[Cp] Country of publication:England
[La] Language:eng
[Mh] MeSH terms primary: Atrial Fibrillation/surgery
Catheter Ablation/adverse effects
Esophageal Fistula/etiology
Heart Atria/pathology
Pneumocephalus/etiology
Pulmonary Veins/surgery
[Mh] MeSH terms secundary: Aged, 80 and over
Atrial Fibrillation/diagnosis
Catheter Ablation/methods
Disease Progression
Esophageal Fistula/radiography
Fatal Outcome
Hemiplegia/diagnosis
Hemiplegia/etiology
Humans
Male
Pneumocephalus/radiography
Seizures/diagnosis
Seizures/etiology
Tomography, X-Ray Computed
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1605
[Cu] Class update date: 160511
[Lr] Last revision date:160511
[Js] Journal subset:IM
[Da] Date of entry for processing:150613
[St] Status:MEDLINE
[do] DOI:10.1093/ehjci/jev089

  9 / 12343 MEDLINE  
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[PMID]: 25863464
[Au] Autor:Kim CY; Lee JS; Kim HD; Kim J; Lee IH
[Ad] Address:Department of Health Science, The Graduate School, Korea University, Jeongneung 3-Dong, Seongbuk-Gu, Seoul 136-703, Republic of Korea. Electronic address: dreampt@korea.ac.kr....
[Ti] Title:Lower extremity muscle activation and function in progressive task-oriented training on the supplementary tilt table during stepping-like movements in patients with acute stroke hemiparesis.
[So] Source:J Electromyogr Kinesiol;25(3):522-30, 2015 Jun.
[Is] ISSN:1873-5711
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:An effective and standardized method for applying a tilt table as a supplementary treatment in the early rehabilitation of stroke patients is still missing. The aim of this study was to determine the influence of progressive task-oriented training on the tilt table on the improvement in lower extremity (LE) muscle activation and clinical function in subjects with hemiplegia due to stroke. Thirty-nine subjects with acute stroke were randomly allocated to three groups; control group, tilt table group, and task-oriented training group on the tilt table, with 13 patients, respectively. All of the subjects received the routine therapy for half an hour, and subjects in the experimental groups additionally received training on two different tilt table applications for 20min a day, five times a week for three weeks. The effect of tilt table applications was assessed using the surface electromyography (EMG) analysis during stepping-like movements on the tilt table for LE muscle activation and clinical scores for function. Our results showed that there was a significantly greater increase in the EMG patterns of the extensors and flexors of the affected leg muscles during flexion and extension movements of both legs and clinical scores in patients undergoing the progressive task-oriented training on the tilt table compared to the other groups. These findings suggest that progressive task-oriented training on the tilt table can improve LE muscle activation and clinical scores of functional performance for early rehabilitation of subjects with acute stroke.
[Mh] MeSH terms primary: Leg/physiopathology
Movement
Muscle, Skeletal/physiopathology
Paresis/physiopathology
Stroke/physiopathology
Tilt-Table Test/methods
[Mh] MeSH terms secundary: Adult
Aged
Electromyography/methods
Female
Gait Disorders, Neurologic/diagnosis
Gait Disorders, Neurologic/etiology
Gait Disorders, Neurologic/physiopathology
Humans
Lower Extremity/physiopathology
Male
Middle Aged
Movement/physiology
Paresis/diagnosis
Paresis/etiology
Random Allocation
Range of Motion, Articular/physiology
Stroke/complications
Stroke/diagnosis
[Pt] Publication type:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Entry month:1512
[Cu] Class update date: 160511
[Lr] Last revision date:160511
[Js] Journal subset:IM
[Da] Date of entry for processing:150513
[St] Status:MEDLINE

  10 / 12343 MEDLINE  
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[PMID]: 27161476
[Au] Autor:Jokovic M; Bogosavljevic V; Nikolic I; Jovanovic N
[Ad] Address:Clinical Center of Serbia, Clinic for Neurosurgery, Belgrade, Serbia.
[Ti] Title:Spontaneous Intracerebral Hematoma in Low-Grade Glioma After 14 Years of Follow-Up.
[So] Source:Turk Neurosurg;26(3):452-5, 2016.
[Is] ISSN:1019-5149
[Cp] Country of publication:Turkey
[La] Language:eng
[Ab] Abstract:We are reporting the case of a 53-year old woman presenting to our hospital with a hemorrhagic low-grade glioma (LGG). She was admitted to a nearby general hospital where she had presented with aphasia, right hemiplegia and change of mental status. Computer tomography (CT) images showed a left temporo-parietal hemorrhage with mass effect. She was transferred to our hospital neuro-intensive care unit where emergency craniotomy was performed. A tumor with hematoma was removed and further histopathology analysis revealed tumor progression. We reviewed the literature reporting cases of central nervous system tumors hemorrhage and found that these types of events are exquisitely rare in adults with LGG. However these events are possible, suggesting that it should be included in the differential diagnosis of any patient presenting with intracranial hemorrhage. This case raises questions regarding the benefit of early versus late intervention for patients known to have LGG.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1605
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.5137/1019-5149.JTN.11004-14.1


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