Database : MEDLINE
Search on : Hemiplegia [Words]
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[PMID]: 23869622
[Au] Autor:Molteni E; Rigoldi C; Morante M; Rozbaczylo C; Haro M; Albertini G; Galli M; Bianchi AM
[Ad] Address:Bioengineering Department , Politecnico di Milano, Milan , Italy .
[Ti] Title:Quantification of long-term effects of botulinum injection in a case of cerebral palsy affecting the upper limb movement.
[So] Source:Dev Neurorehabil;18(3):145-8, 2015 Jun.
[Is] ISSN:1751-8431
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The aim of this work was to put into evidence the long-lasting modification induced by botulinum toxin injection and rehabilitative treatment on motor control. METHODS: In this contribution, we report the case of a female child showing hemiplegia, due to cerebral palsy. She underwent botulinum injection, followed by physical and occupational therapy. We quantified the biomechanical, cerebral and occupational aspects of her impaired upper limb, also dynamically, with respect to her pre- and post-treatment condition. RESULTS: Small long-lasting improvements - induced on biomechanics by botulinum injection - triggered wide cerebral modification, well reflected in improved contextual movements and motor strategy. CONCLUSION: These results provide evidences that small modifications in the end-effector performance often imply cerebral modifications and improvement in finalized motor strategy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3109/17518423.2013.796018

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[PMID]: 25230986
[Au] Autor:Giannantoni NM; Broccolini A; Frisullo G; Pilato F; Profice P; Morosetti R; Di Lella G; Zampino G; Della Marca G
[Ad] Address:Institute of Neurology, Catholic University, Rome, Italy.
[Ti] Title:Neurofibromatosis type 1 associated with vertebrobasilar dolichoectasia and pontine ischemic stroke.
[So] Source:J Neuroimaging;25(3):505-6, 2015 May.
[Is] ISSN:1552-6569
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Neurofibromatosis type 1 (NF1) is a heterogeneous, common, neurocutaneous disorder presenting different complications during a life span, including cerebrovascular dysplasia. To our knowledge this is the first reported case of NF1 associated with vertebrobasilar dolichoectasia and pontine ischemic stroke. We describe a 57-year-old man with NF1 who presented an acute onset right-sided facial palsy and hemiplegia, dysarthria, and gait imbalance. Magnetic resonance imaging showed an acute left paramedian pontine infarct and a hypoplastic right vertebral artery. Brain Computed Tomography Angiography revealed the occurrence of vertebrobasilar dolichoectasia. Co-occurrence of VBD and NF1 might not be merely casual and it may significantly heighten the mortality rate in this multisystem disorder. We suggest a possible role of VBD in the genesis of our patient's clinical-radiological features and prompt the early detection of asymptomatic arteriopathy in individuals with NF1 in order to ameliorate patients' quality of life and life expectancy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1111/jon.12160

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[PMID]: 25731059
[Au] Autor:Saho M; Ito A; Hiraki T; Ushijima K
[Ti] Title:[Anesthetic management of a patient with Trousseau's syndrome and ovarian cancer who underwent gynecological surgery].
[So] Source:Masui;63(11):1257-60, 2014 Nov.
[Is] ISSN:0021-4892
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:Trousseau's syndrome, a complex paraneoplastic disease, is characterized by the occurrence of thromboembolic disorders such as brain infarctions in patients with malignant neoplasms. We report the case of a 46-year-old woman with ovarian cancer who had suffered cerebral infarctions and presented with left hemiplegia, aphasia, and atypical genital bleeding. She suffered multiple right brain infarctions, a pulmonary embolism, a right renal infarction with bilateral hydronephrosis and deep venous thromboses and exhibited increased D-dimer and fibrinogen levels and so was administered heparin (10,000 U x day(-1)). She had no other underlying diseases such as coagulopathy, cardiovascular disease, collagen disease, or angiitis. Therefore, we were able to diagnose her with Trousseau's syndrome. She was scheduled to undergo total abdominal hysterectomy with bilateral oophorectomy, pelvic lymphadenectomies, and omentectomy. Preoperatively, an inferior vena cava filter was temporarily installed to prevent the development of further pulmonary thromboses. General anesthesia was uneventfully maintained by inhalation of oxygen, air, and sevoflurane and the continuous infusion of remifentanil whilst regional cerebral oxygen saturation and transesophageal echocardiography monitoring were performed. Postoperatively, she received heparin-based anticoagulant therapy (10,000 U x day(-1)) and did not exhibit bleeding diathesis or thrombosis. It is of great importance that anesthesiologists are aware of the thromboembolic status of patients with malignant neoplasms, especially those with gynecological tumors.
[Mh] MeSH terms primary: Ovarian Neoplasms/surgery
Thromboembolism/etiology
[Mh] MeSH terms secundary: Anesthesia, General
Female
Humans
Hysterectomy
Middle Aged
Ovarian Neoplasms/complications
[Pt] Publication type:CASE REPORTS; ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:150303
[St] Status:MEDLINE

  4 / 11954 MEDLINE  
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[PMID]: 25366947
[Au] Autor:Mafrici M; Salomone M; Valente S; Gerace E; Trabucco P; Navarre S; Villain M; Vingolo EM
[Ad] Address:Dipartimento di Scienze Medico-Chirurgiche, U.O.S. Oftalmologia, Università 'Sapienza' di Roma, Terracina, Italia....
[Ti] Title:Epiteliopatia acuta multifocale posteriore a placche di pigmento e coinvolgimento neurologico in un paziente anziano: caso clinico e revisione della letteratura. [Acute posterior multifocal placoid pigment epiteliopathy and neurological involvement in an elderly patient: case report and review].
[So] Source:Clin Ter;165(5):261-8, 2014.
[Is] ISSN:1972-6007
[Cp] Country of publication:Italy
[La] Language:ita
[Ab] Abstract:We report a rare case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in an elderly patient and a review of the recent scientific literature. A 65-year-old Caucasian man, forty-five days after return from tropical travel he developed right-sided facial palsy with right hemiplegia, dysarthria and a positive Babinski sign. He started prednisone 90 mg/day. Clinical, laboratory and imaging examinations were reported. Five months later there was a complete neurological and ophthalmological recovery. Although APMPPE was described primarily in young adults, we report the first case of APMPPE associated with neurological involvement in an older patient with a complete restitutio ad integrum.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1411
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.7417/CT.2014.1757

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[PMID]: 25133319
[Au] Autor:Kortte KB; McWhorter JW; Pawlak MA; Slentz J; Sur S; Hillis AE
[Ad] Address:Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine....
[Ti] Title:Anosognosia for hemiplegia: The contributory role of right inferior frontal gyrus.
[So] Source:Neuropsychology;29(3):421-32, 2015 May.
[Is] ISSN:1931-1559
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Awareness of motor functioning is most likely a complex process that requires integration of sensory-motor feedback to constantly update the system on the functioning of the limb during motor behavior. Using lesion mapping procedures and behavioral measures, the current study aimed to evaluate neural correlates of anosognosia for hemiplegia (AHP) in the acute stage (first 48 hr) of right hemisphere stroke. METHOD: Thirty-five individuals with right hemisphere stroke who presented to an urban medical center within 24 hr of symptom onset were included in the study. All 35 individuals had hemiplegia, and 8 of these individuals exhibited AHP. RESULTS: Fisher's exact test statistical map of lesion-deficit association (range is between-log(p) 4 to 11) found maximal value of 10.9 located in pars orbitalis (Brodmann's Area 47; BA). In this selected location, 6 out of 8 patients with AHP had tissue abnormality, whereas none of the unaffected subjects had tissue abnormality in BA 47. Right BA 44/45 was also found to be lesioned more frequently in individuals with AHP (75%) than without AHP (11%). CONCLUSIONS: The current study findings provide preliminary support for unique involvement of the right inferior frontal gyrus (IFG), pars orbitalis (BA 47) in AHP. The current data suggest that frontal operculum may play a key role in awareness of limb functioning. (PsycINFO Database Record
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150506
[Lr] Last revision date:150506
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1037/neu0000135

  6 / 11954 MEDLINE  
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[PMID]: 25173354
[Au] Autor:Okano N; Uchino A; Saito N; Maruyama H
[Ad] Address:Department of Diagnostic Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan, nanami@saitama-med.ac.jp.
[Ti] Title:Left carotid-anterior cerebral artery anastomosis diagnosed by MR angiography: a case report.
[So] Source:Surg Radiol Anat;37(3):311-3, 2015 Apr.
[Is] ISSN:1279-8517
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Anastomosis of the carotid-anterior cerebral artery (ACA) is a rare anomalous vessel that arises from the internal carotid artery (ICA) at the level of the ophthalmic artery and takes an infraoptic and prechiasmatic path to anastomose with the ACA. It has known right-sided predominance. We report the case of an 83-year-old man with a left carotid-ACA anastomosis that was diagnosed by magnetic resonance (MR) angiography from the neck to the head during investigation of transient left hemiplegia. The right ICA was occluded at its origin. Our literature search revealed only six reported cases of left carotid-ACA anastomoses. We believe ours is the first case diagnosed by MR angiography.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1007/s00276-014-1358-7

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[PMID]: 25743863
[Au] Autor:Gudmundsdottir JF; Geirsson A; Hannesson P; Gudbjartsson T
[Ad] Address:Departments of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland....
[Ti] Title:Major ischaemic stroke caused by an air embolism from a ruptured giant pulmonary bulla.
[So] Source:BMJ Case Rep;2015, 2015.
[Is] ISSN:1757-790X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:We report an extremely rare complication of a major ischaemic cerebral event caused by an air embolism due to spontaneous rupture of a giant pulmonary bulla that occurred during an airline flight. Shortly after take-off, the patient experienced sudden right-sided hemiplegia and dyspnoea. Following an emergency landing in Reykjavik, a CT scan of the brain showed minute air bubbles consistent with air emboli within the left-sided intracerebral arteries, and MRI showed signs of acute ischaemic cerebral infarction in the left hemisphere. The patient later underwent a pulmonary lobectomy and survived this life-threatening complication with relatively mild neurological sequelae.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1503
[Js] Journal subset:IM
[St] Status:In-Process

  8 / 11954 MEDLINE  
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[PMID]: 25656163
[Au] Autor:Paciorkowski AR; McDaniel SS; Jansen LA; Tully H; Tuttle E; Ghoneim DH; Tupal S; Gunter SA; Vasta V; Zhang Q; Tran T; Liu YB; Ozelius LJ; Brashear A; Sweadner KJ; Dobyns WB; Hahn S
[Ad] Address:Departments of Neurology, Pediatrics, and Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, U.S.A; Center for Neural Development and Disease, University of Rochester Medical Center, Rochester, New York, U.S.A.
[Ti] Title:Novel mutations in ATP1A3 associated with catastrophic early life epilepsy, episodic prolonged apnea, and postnatal microcephaly.
[So] Source:Epilepsia;56(3):422-30, 2015 Mar.
[Is] ISSN:1528-1167
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Mutations of ATP1A3 have been associated with rapid onset dystonia-parkinsonism and more recently with alternating hemiplegia of childhood. Here we report one child with catastrophic early life epilepsy and shortened survival, and another with epilepsy, episodic prolonged apnea, postnatal microcephaly, and severe developmental disability. Novel heterozygous mutations (p.Gly358Val and p.Ile363Asn) were identified in ATP1A3 in these children. METHODS: Subjects underwent next-generation sequencing under a research protocol. Clinical data were collected retrospectively. The biochemical effects of the mutations on ATP1A3 protein function were investigated. Postmortem neuropathologic specimens from control and affected subjects were studied. RESULTS: The mutations localized to the P domain of the Na,K-ATPase α3 protein, and resulted in significant reduction of Na,K-ATPase activity in vitro. We demonstrate in both control human brain tissue and that from the subject with the p.Gly358Val mutation that ATP1A3 immunofluorescence is prominently associated with interneurons in the cortex, which may provide some insight into the pathogenesis of the disease. SIGNIFICANCE: The findings indicate these mutations cause severe phenotypes of ATP1A3-related disorder spectrum that include catastrophic early life epilepsy, episodic apnea, and postnatal microcephaly.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Entry month:1503
[Cu] Class update date: 150319
[Lr] Last revision date:150319
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1111/epi.12914

  9 / 11954 MEDLINE  
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[PMID]: 24087981
[Au] Autor:Camerota F; Galli M; Cimolin V; Celletti C; Ancillao A; Blow D; Albertini G
[Ad] Address:Physical Medicine and Rehabilitation Division, Orthopaedic Department, Umberto I Hospital, Sapienza University , Rome , Italy .
[Ti] Title:Neuromuscular taping for the upper limb in Cerebral Palsy: A case study in a patient with hemiplegia.
[So] Source:Dev Neurorehabil;17(6):384-7, 2014 Dec.
[Is] ISSN:1751-8431
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To assess quantitatively the effects of Neuromuscular Taping (NMT) on the upper limb in a female child with left hemiplegia, due to Cerebral Palsy (CP). METHODS: The patient underwent NMT on cervical level, shoulder and hand only of the plegic upper limb, followed by physical therapy. Kinematic data of upper limbs during reaching task were collected before (PRE) and after 2 weeks of treatment (POST). RESULTS: After the intervention, the affected limb improved in terms of movement duration, Average Jerk and Number of Unit Movements indices, indicating a faster, smoother and less segmented movement. Improvements appeared at the ranges of motion of the upper limb joints, both at shoulder and elbow joints. No significant changes were globally displayed for the unaffected arm. CONCLUSION: NMT seems to be a promising intervention for improving upper limb movement in patients with CP. Further investigations are certainly needed to assess effectively the effects of the intervention in this pathological state.
[Mh] MeSH terms primary: Cerebral Palsy/physiopathology
Hemiplegia/physiopathology
[Mh] MeSH terms secundary: Adolescent
Arm
Biomechanical Phenomena
Cerebral Palsy/complications
Child
Extremities
Female
Hand
Hemiplegia/complications
Humans
Movement
Treatment Outcome
Upper Extremity/physiopathology
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:141106
[St] Status:MEDLINE
[do] DOI:10.3109/17518423.2013.830152

  10 / 11954 MEDLINE  
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[PMID]: 25931770
[Au] Autor:Park J; Lee N; Cho Y; Yang Y
[Ad] Address:Department of Occupational Therapy, Kyungbuk College, Republic of Korea ; Department of Rehabilitation Science, Graduate School, Inje University, Republic of Korea....
[Ti] Title:Modified constraint-induced movement therapy for clients with chronic stroke: interrupted time series (ITS) design.
[So] Source:J Phys Ther Sci;27(3):963-6, 2015 Mar.
[Is] ISSN:0915-5287
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:[Purpose] The purpose of this study was to investigate the impact that modified constraint-induced movement therapy has on upper extremity function and the daily life of chronic stroke patients. [Subjects and Methods] Modified constraint-induced movement therapy was conduct for 2 stroke patients with hemiplegia. It was performed 5 days a week for 2 weeks, and the participants performed their daily living activities wearing mittens for 6 hours a day, including the 2 hours of the therapy program. The assessment was conducted 5 times in 3 weeks before and after intervention. The upper extremity function was measured using the box and block test and a dynamometer, and performance daily of living activities was assessed using the modified Barthel index. The results were analyzed using a scatterplot and linear regression. [Results] All the upper extremity functions of the participants all improved after the modified constraint-induced movement therapy. Performance of daily living activities by participant 1 showed no change, but the results of participant 2 had improved after the intervention. [Conclusion] Through the results of this research, it was identified that modified constraint-induced movement therapy is effective at improving the upper extremity functions and the performance of daily living activities of chronic stroke patients.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150503
[Lr] Last revision date:150503
[Da] Date of entry for processing:150501
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1589/jpts.27.963


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