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[PMID]: 29516936
[Au] Autor:Kishanprasad HL; Lobo L; Shetty JK; Impana BD
[Ad] Address:Department of Pathology, KS Hegde Medical Academy, Nitte University, Mangalore, Karnataka, India.
[Ti] Title:Giant cells in soft tissue tumors! Is it a clue to diagnosis or cytologists mystery??? An unusual case report.
[So] Source:J Cancer Res Ther;14(2):444-446, 2018 Jan-Mar.
[Is] ISSN:1998-4138
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Giant cells in soft tissue (ST) tumors are rare, pose great challenges to treating clinicians, and diagnosing pathologists. Common lesion with giant cells includes benign conditions such as nodular fasciitis to highly malignant lesions such as giant cell variant of malignant fibrous histiocytoma and extraskeletal osteosarcoma. Giant cell tumors of ST, extension of bony lesion to the ST are also rare possibilities. Recently, giant cell fibroblastoma and dermatofibrosarcoma protuberans have also been added to this list. These tumors show unpredictable behavior; some patients are cured by simple surgical excision whereas others develop metastasis. Diagnosing these in cytology is still more challenging. We report here a rare case of a giant cell-rich dermatofibrosarcoma protuberans in a 23-year-old male who presented with ST lesion in left forearm since 6 months. The lesion was predicted in fine-needle aspiration cytology and confirmed later with histopathology. When evaluated along with clinical features, the cytological features are very useful to distinguish between these tumors with giant cell morphology.
[Pt] Publication type:LETTER
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.4103/0973-1482.199433

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[PMID]: 29429159
[Au] Autor:Liu L; Wang LH; Ren YB; Rao XS; Yang SM
[Ad] Address:Department of Pathology, Peking University International Hospital, Beijing 102206, China.
[Ti] Title:[Retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic differentiation: a clinicopathological analysis].
[So] Source:Zhonghua Bing Li Xue Za Zhi;47(2):94-98, 2018 Feb 08.
[Is] ISSN:0529-5807
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To investigate the clinicopathological features, differential diagnosis, treatment and prognosis of dedifferentiated liposarcoma with rhabdomyoblastic differentiation. Six cases of retroperitoneal dedifferentiated liposarcoma with rhabdomyoblastic features were collected from December 2014 to August 2017 at Peking University International Hospital. The clinical manifestations, histomorphology, immunophenotype, treatment and follow-up data were analyzed, and relevant literature reviewed. The six patients included two males and four females, with age range of 47 to 66 years (mean 56 years). One case was primary and the five cases were recurred; four cases received radiotherapy and/or chemotherapy. The tumor diameters were 10 to 30 cm. Microscopically, the dedifferentiated areas were well demarcated from the well-differentiated areas, and resembled malignant fibrous histiocytoma, fibrosarcoma or solitary fibrous tumor with obvious mitotic figures or necrosis. Rhabdomyoblastic cells made up 10% to 30% of dedifferentiated area, and were scattered or focally distributed, being rounded, band-like or spindled, mostly with abundant eosinophilic cytoplasm. No striated structure was found, and the nucleis were rounded, oval or irregular shape with central or eccentric prominent nucleoli. Rare rhabdomyoblastic cells were lymphocytoid. The tumors encroached the muscular layer of intestinal wall in two cases and perirenal adipose tissue in one case. By immunohistochemical staining, the rhabdomyoblastic cells of all cases were all positive for desmin, myogenin, myoD1 and SMA; S-100 protein was expressed in one case (1/6). Well-differentiated area in two cases and dedifferentiated areas in all six cases were positive for MDM2, CDK4 and p16. After resection of the tumor and adjacent organs, one case recurred three months later, but there was no distant metastasis. Dedifferentiated liposarcoma with rhabdomyoblastic differentiation is a rare dedifferentiated liposarcoma. Pathological diagnosis is based on morphology, with supplementary immunohistochemical or molecular evaluation for further differential diagnosis. Multiple relapses may occur after surgical ablation plus adjuvant therapy.
[Mh] MeSH terms primary: Liposarcoma/pathology
Retroperitoneal Neoplasms/pathology
[Mh] MeSH terms secundary: Aged
Cell Count
Cell Differentiation
Diagnosis, Differential
Female
Fibrosarcoma/pathology
Histiocytoma, Malignant Fibrous/pathology
Humans
Immunophenotyping
Liposarcoma/therapy
Male
Middle Aged
Neoplasm Recurrence, Local
Prognosis
Retroperitoneal Neoplasms/therapy
Solitary Fibrous Tumors/pathology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0529-5807.2018.02.003

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[PMID]: 29429158
[Au] Autor:Sun M; Liu JG; Weng QY; Yu L; Wang J
[Ad] Address:Department of Pathology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
[Ti] Title:[Pleomorphic and dedifferentiated leiomyosarcoma: a clinicopathologic analysis].
[So] Source:Zhonghua Bing Li Xue Za Zhi;47(2):87-93, 2018 Feb 08.
[Is] ISSN:0529-5807
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To investigate the clinicopathologic features, differential diagnosis and biological behavior of pleomorphic leiomyosarcoma (PLMS) and dedifferentiated leiomyosarcoma (DLMS). Forty-nine cases were collected from November 2007 to December 2016, including eight that diagnosed at Fudan University Shanghai Cancer Center, and 41 consultation cases. The clinical findings and pathologic features were reviewed. Immunophenotype was obtained in 33 cases and follow-up information was available in 38 cases. There were 22 males and 27 females with ages ranging from 24 to 83 years (mean 52.5 years). Fifteen cases occurred in extremities, 14 in deep body cavity, 11 in the trunk, 4 in the head and neck, 2 in the bladder, and 1 each in the inguinal region, perineum and femoral vein, respectively. Tumor sizes ranged from 3 to 30 cm (mean 9.1 cm). The tumors were composed of at least small foci of typical leiomyosarcoma (LMS) and areas of high-grade pleomorphic/undifferentiated sarcoma. The typical LMS component showed the characteristic morphology of smooth muscle differentiation and was low to intermediate grade in most cases. Pleomorphic areas were mainly composed of atypical spindle and polygonal cells admixed with variable large, bizarre atypical cells and multinuclear giant cells, mostly mimicking undifferentiated pleomorphic sarcoma. The pleomorphic and leiomyosarcomatous areas were usually intermixed, but the demarcation may be distinct or gradual in some cases. The classical LMS component was positive for at least one myogenic marker: α-SMA in 97.0%(32/33), desmin in 72.7%(24/33), H-caldesmon in 90.9% (20/22), MSA in 14/16, and calponin in 15/15 of cases. The pleomorphic sarcoma component was reactive for at least one myogenic marker in 87.9% (29/33) of cases, usually showing focal and less intense immunoreactivity than classical LMS component: α-SMA was positive in 81.8%(27/33), desmin in 48.5%(16/33), H-caldesmon in 72.7% (16/22), MSA in 12/16, and calponin in 11/15 of cases. Based on staining for muscle markers in the pleomorphic component, 29 cases were designated as PLMS, 4 as DLMS. Ki-67 index ranged from 15% to 70% (mean 40%). Follow-up data was available in 38 cases (77.6%), of which 11 patients (28.9%) died of disease, 12 patients were alive with unresectable or recurrent disease, 14 patients were alive with no evidence of disease and another one died of unrelated cause. The median disease-free and overall survival was 6 and 10 months respectively. Twelve patients exhibited local recurrence and 11 developed metastases. The median interval to progression was 8 months. The identification of areas of typical LMS is crucial for accurate diagnosis of PLMS and DLMS. Both PLMS and DLMS show more aggressive behavior and poorer prognosis than ordinary LMS.
[Mh] MeSH terms primary: Leiomyosarcoma/pathology
Skin Neoplasms/pathology
[Mh] MeSH terms secundary: Actins/analysis
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor/analysis
Calcium-Binding Proteins/analysis
Calmodulin-Binding Proteins/analysis
Cell Differentiation
China
Desmin/analysis
Diagnosis, Differential
Extremities
Female
Histiocytoma, Malignant Fibrous/chemistry
Histiocytoma, Malignant Fibrous/pathology
Humans
Immunohistochemistry
Immunophenotyping
Leiomyosarcoma/chemistry
Male
Microfilament Proteins/analysis
Middle Aged
Neoplasm Recurrence, Local
Skin Neoplasms/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (ACTA2 protein, human); 0 (Actins); 0 (Biomarkers, Tumor); 0 (Calcium-Binding Proteins); 0 (Calmodulin-Binding Proteins); 0 (Desmin); 0 (Microfilament Proteins); 0 (calponin)
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0529-5807.2018.02.002

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[PMID]: 29485437
[Au] Autor:Liu Y; Xu B
[Ad] Address:From the Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing, 100853, China. Conflicts of interest and sources of funding: none declared.
[Ti] Title:Primary Hepatic Malignant Fibrous Histiocytoma on PET/CT.
[So] Source:Clin Nucl Med;, 2018 Feb 27.
[Is] ISSN:1536-0229
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Malignant fibrous histiocytoma is mainly presented in extremities, less commonly in posterior peritoneum, but primary presented in liver is very rare and often with a poor prognosis because of its high aggression. The features of clinical presentations and images are variable and the pre-operative diagnosis is difficult. Here, we report a primary hepatic malignant fibrous histiocytoma patient with no distant metastasis showed on pre-operative F-FDG PET/CT, however with many metastases showed on the post-operative F-FDG PET/CT.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher
[do] DOI:10.1097/RLU.0000000000002039

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[PMID]: 29494378
[Au] Autor:Santamaria JA; Gallagher CF; Mehta A; Davies BW
[Ad] Address:Department of Ophthalmology, San Antonio Military Medical Center, San Antonio, Texas, U.S.A.
[Ti] Title:Fibrous Histiocytoma of the Lacrimal Sac in an 11-Year-Old Male.
[So] Source:Ophthal Plast Reconstr Surg;, 2018 Feb 27.
[Is] ISSN:1537-2677
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Fibrous histiocytoma is a soft tissue tumor with cells resembling both fibroblasts and histiocytes. Occasionally in the orbit, they rarely arise in the lacrimal sac. Similar to prior cases described, the patient presented with symptoms of epiphora and a slowly enlarging mass inferior to the right medial canthus. Imaging demonstrated a circumscribed 1.2 cm × 1.1 cm × 1.1 cm mass within the lacrimal sac without surrounding bony destruction. Grossly, the tumor appeared homogenous and rubbery. Pathologic study results from the case demonstrated zones of hypercellularity and hypocellularity with a fibrous appearance, admixed with spindle cells and collections of foamy histiocytes. A diagnosis of benign fibrous histiocytoma was rendered, with the patient experiencing a complete resolution of symptoms at subsequent follow up. To the authors' knowledge, this is the first reported solitary case report of a fibrous histiocytoma of the lacrimal sac in a pediatric patient.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[St] Status:Publisher
[do] DOI:10.1097/IOP.0000000000001086

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[PMID]: 29465573
[Au] Autor:Li X; Zhang Z; Latif M; Chen W; Cui J; Peng Z
[Ad] Address:Department of Radiology, the Third Hospital of Hebei Medical University.
[Ti] Title:Synovium as a widespread pathway to the adjacent joint in undifferentiated high-grade pleomorphic sarcoma of the tibia: A case report.
[So] Source:Medicine (Baltimore);97(8):e9870, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Undifferentiated high-grade pleomorphic sarcoma (UPS), originated from bone, is a rare tumor, accounting for 2% to 5% of all primary maligment bone neoplasms. Skip lesion can be found in undifferentiated high-grade pleomorphic sarcoma of bone (UPS-B). However, the direct invasion across the articular synovium to bone has not been reported previously. PATIENT CONCERNS: We report an unusual case of a 65-year-old man complained of a year history of pain, swelling, and limitation of activity in the left knee joint. At the proximal tibia, there was extensive invasion of articular synovium, which provides a direct anatomic pathway for the tumor invasion to the adjacent bone, including patella and femoral condyle. DIAGNOSES: Magnetic resonance imaging was important in defining the marrow involvement and joint invasion, including the thickening articular synovium. Subsequent pathological examination confirmed the diagnosis of UPS. INTERVENTIONS: The patient underwent an extensive resection of the knee joint, except for the patellar. OUTCOMES: After operation, routine chemotherapy was performed. Unfortunately, half a year later, soft tissue swelling of whole thigh was found. Then this patient came our hospital again. Positron emission tomography imaging showed there was recurrence of UPS with lung metastasis. A week later, this patient died. LESSONS: In contrast to frequent infiltration pathway, the articular synovium as a media for this tumor spread is rare. This study adds a better understanding of this direct invasion way to the medical literature.
[Mh] MeSH terms primary: Bone Neoplasms/pathology
Histiocytoma, Malignant Fibrous/pathology
Synovial Membrane/pathology
Tibia/pathology
[Mh] MeSH terms secundary: Aged
Bone Neoplasms/diagnostic imaging
Bone Neoplasms/surgery
Fatal Outcome
Femoral Neoplasms/diagnostic imaging
Femoral Neoplasms/pathology
Femoral Neoplasms/surgery
Histiocytoma, Malignant Fibrous/diagnostic imaging
Histiocytoma, Malignant Fibrous/surgery
Humans
Knee Joint/diagnostic imaging
Knee Joint/pathology
Knee Joint/surgery
Lung Neoplasms/secondary
Magnetic Resonance Imaging
Male
Neoplasm Invasiveness
Patella/diagnostic imaging
Patella/pathology
Patella/surgery
Synovial Membrane/diagnostic imaging
Thigh/diagnostic imaging
Thigh/pathology
Tibia/diagnostic imaging
Tibia/surgery
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009870

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[PMID]: 28463156
[Au] Autor:Demizu Y; Jin D; Sulaiman NS; Nagano F; Terashima K; Tokumaru S; Akagi T; Fujii O; Daimon T; Sasaki R; Fuwa N; Okimoto T
[Ad] Address:Department of Radiology, Hyogo Ion Beam Medical Center, Tatsuno, Hyogo, Japan. Electronic address: y_demizu@nifty.com.
[Ti] Title:Particle Therapy Using Protons or Carbon Ions for Unresectable or Incompletely Resected Bone and Soft Tissue Sarcomas of the Pelvis.
[So] Source:Int J Radiat Oncol Biol Phys;98(2):367-374, 2017 06 01.
[Is] ISSN:1879-355X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: To retrospectively analyze the treatment outcomes of particle therapy using protons or carbon ions for unresectable or incompletely resected bone and soft tissue sarcomas (BSTSs) of the pelvis. METHODS AND MATERIALS: From May 2005 to December 2014, 91 patients with nonmetastatic histologically proven unresectable or incompletely resected pelvic BSTSs underwent particle therapy with curative intent. The particle therapy used protons (52 patients) or carbon ions (39 patients). All patients received a dose of 70.4 Gy (relative biologic effectiveness) in 32 fractions (55 patients) or 16 fractions (36 patients). RESULTS: The median patient age was 67 years (range 18-87). The median planning target volume (PTV) was 455 cm (range 108-1984). The histologic type was chordoma in 53 patients, chondrosarcoma in 14, osteosarcoma in 10, malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma in 5, and other in 9 patients. Of the 91 patients, 82 had a primary tumor and 9 a recurrent tumor. The median follow-up period was 32 months (range 3-112). The 3-year rate of overall survival (OS), progression-free survival (PFS), and local control was 83%, 72%, and 92%, respectively. A Cox proportional hazards model revealed that chordoma histologic features and a PTV of ≤500 cm were significantly associated with better OS, and a primary tumor and PTV of ≤500 cm were significantly associated with better PFS. Ion type and number of fractions were not significantly associated with OS, PFS, or local control. Late grade ≥3 toxicities were observed in 23 patients. Compared with the 32-fraction protocol, the 16-fraction protocol was associated with significantly more frequent late grade ≥3 toxicities (18 of 36 vs 5 of 55; P<.001). CONCLUSIONS: Particle therapy using protons or carbon ions was effective for unresectable or incompletely resected pelvic BSTS, and the 32-fraction protocol was effective and relatively less toxic. Nevertheless, a longer follow-up period is needed to confirm these results.
[Mh] MeSH terms primary: Bone Neoplasms/radiotherapy
Heavy Ion Radiotherapy/methods
Pelvic Bones
Proton Therapy/methods
Sarcoma/radiotherapy
[Mh] MeSH terms secundary: Aged
Bone Neoplasms/diagnostic imaging
Bone Neoplasms/mortality
Bone Neoplasms/surgery
Chondrosarcoma/mortality
Chondrosarcoma/radiotherapy
Chondrosarcoma/surgery
Chordoma/diagnostic imaging
Chordoma/mortality
Chordoma/radiotherapy
Chordoma/surgery
Female
Heavy Ion Radiotherapy/statistics & numerical data
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Osteosarcoma/mortality
Osteosarcoma/radiotherapy
Osteosarcoma/surgery
Pelvic Bones/diagnostic imaging
Proportional Hazards Models
Proton Therapy/statistics & numerical data
Radiotherapy Planning, Computer-Assisted/methods
Relative Biological Effectiveness
Retrospective Studies
Sarcoma/diagnostic imaging
Sarcoma/mortality
Sarcoma/surgery
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1707
[Cu] Class update date: 180228
[Lr] Last revision date:180228
[Js] Journal subset:IM
[Da] Date of entry for processing:170503
[St] Status:MEDLINE

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[PMID]: 29475731
[Au] Autor:Coquard R; N'Guyen AM; Mathis T; Josserand-Pietri F; Khodri M; Largeron G; Barbet N; Grange JD
[Ad] Address:Centre de radiothérapie Bayard, 44, avenue Condorcet, 69100 Villeurbanne, France. Electronic address: coquard.regis@wanadoo.fr.
[Ti] Title:Radiothérapie de contact adjuvante des tumeurs malignes de la conjonctive : résultats préliminaires d'une série de 14 patients traités avec l'appareil Papillon 50. [Adjuvant contact radiotherapy for conjunctival malignancies: Preliminary results of a series of 14 patients treated with the Papillon 50 machine].
[So] Source:Cancer Radiother;, 2018 Feb 20.
[Is] ISSN:1769-6658
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:PURPOSE: To evaluate the results of an adjuvant contact irradiation using 50kV photons after resection of conjunctival malignancies. MATERIALS AND METHOD: From 2012 to 2014, 14 patients (male: nine; female: five) have been treated by contact irradiation after resection of a malignant tumor of the conjunctiva (melanoma: five patients; malignant fibrous histiocytoma: one patient; carcinoma: eight patients) The treatment was performed using the Papillon 50 machine (Ariane). Three to four sessions were delivered, each giving a dose of 10Gy. The median follow-up in survivors was 33 months. RESULTS: The tolerance was good. A cataract was seen in one patient, and a moderate eye dryness in one. There was no corneal ulcer. One patient died of intercurrent disease. One patient with carcinoma recurred locally. CONCLUSION: Adjuvant contact radiotherapy provides a good local control after resection of conjunctival malignancies (melanoma, malignant histiocytofibroma, carcinoma). Thanks to its precision, this technique is well tolerated with a low rate of complications. Furthermore, it is delivered on an ambulatory basis.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180224
[Lr] Last revision date:180224
[St] Status:Publisher

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[PMID]: 29472492
[Au] Autor:Morgan LM; Miller ER; Raj AB; Coventry SC; Elster JD
[Ad] Address:Department of Pediatrics, University of Louisville, Louisville, Kentucky lerraughn2013@gmail.com.
[Ti] Title:Angiomatoid Fibrous Histiocytoma With Paraneoplastic Platelet Storage Pool Deficiency.
[So] Source:Pediatrics;, 2018 Feb 22.
[Is] ISSN:1098-4275
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Angiomatoid fibrous histiocytoma is a rare soft tissue tumor usually discovered in young individuals. This tumor is often mistaken for a hematoma and typically misdiagnosed. It is commonly found in the extremities and may be associated with a site of recent or previous trauma. Characteristic histology includes nodules of histiocytoid spindle cells with pseudoangiomatoid spaces, fibrous pseudocapsules, and lymphoid cuffing. We describe the case of an 8-year-old girl who presented after incision and drainage of a superficial thigh lesion and experienced subsequent chronic bleeding of her wound. Her initial presentation was concerning for an underlying bleeding disorder, and laboratory analysis uncovered a paraneoplastic platelet function disorder that resolved with therapy of the primary tumor.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180223
[Lr] Last revision date:180223
[St] Status:Publisher

  10 / 7951 MEDLINE  
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[PMID]: 29471212
[Au] Autor:Khanna V; Rajan M; Reddy T; Alexander N; Surendran P
[Ad] Address:Sri Ramachandra Medical College, Porur, Chennai - 600116, Tamil Nadu, India. Electronic address: vatsal_khanna@yahoo.com.
[Ti] Title:Nodular fasciitis mimicking a soft tissue sarcoma - A case report.
[So] Source:Int J Surg Case Rep;44:29-32, 2018 Feb 15.
[Is] ISSN:2210-2612
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Nodular Fasciitis, also known as infiltrative or pseudosarcomatous fasciitis, is a benign soft tissue tumour of fibroblastic/myofibroblastic differentiation, that was first described in 1955 by Konwaler et al. PRESENTATION OF CASE: This is a case report of a 27-year old male with complaints of a swelling in the right axilla for 2 and ½ years measuring 12 cm × 10 cm. Chest X-Ray was normal. Magnetic Resonance Imaging of the right arm and chest showed an irregular mass in the axilla in the muscular-subcutaneous plane measuring 10.8 cm × 8.8 cm × 12 cm, with no neural involvement. Magnetic Resonance Angiogram showed feeders from the branches of the Right Subclavian and Right Axillary Artery and venous drainage into the Right Subclavian Vein. USG guided biopsy was done which showed benign spindle cell neoplasm. Patient underwent wide local excision under general anesthesia. The specimen was sent for histopathological examination which showed histological and immunohistochemical features in favour of Nodular Fasciitis. DISCUSSION: Most nodular fasciitis lesions are solitary and occur in adults 20-40 years of age. Nodular fasciitis affects both men and women with equal frequency. Differential diagnosis of nodular fasciitis includes, fibrosarcoma, fibroma, fibrous histiocytoma, and desmoids and histopathology and immunohistochemistry play a key role in identifying the condition. CONCLUSION: Owing to the size, location and findings of the Magnetic Resonance Angiogram we initially suspected a Soft Tissue Sarcoma, but to our surprise, on further investigation the mass was revealed to be Nodular Fasciitis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180222
[Lr] Last revision date:180222
[St] Status:Publisher


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