Database : MEDLINE
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[PMID]: 29501044
[Au] Autor:Essa AA; Hamdan AR
[Ad] Address:Department of Neurosurgery, Faculty of Medicine, Assiut University Hospital, Assiut, Egypt. Electronic address: abdelhakeemessa@aun.edu.eg.
[Ti] Title:Sphenoid meningioma enplaque with proptosis: Surgical excision, reconstruction and outcome.
[So] Source:Clin Neurol Neurosurg;167:147-156, 2018 Feb 21.
[Is] ISSN:1872-6968
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To evaluate surgical outcome and reconstruction of bone defects after excision of sphenoid meningioma enplaque. PATIENT AND METHODS: Between June 2012 and May 2016, a series of 15 patients presented by proptosis attended to neurosurgery departments, Assiut university hospital, Qena university hospital, South Valley University and, These patients were diagnosed with sphenoid meningioma enplaque by fulfilling its criteria by neuroimaging (sheet-like meningioma and hyperostosis). All patients received preoperative imaging investigations including Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) to evaluate the extension of both tumor components - soft tissue and bone involvement. Fifteen patients were operated by pterional approach under general anesthesia. RESULTS: Fifteen patients with meningioma enplaque were treated surgically. The mean age of patients at the time of admission was 46.5 years, age ranged between 35-56 years. 80% of patients were females (female to male ratio was 4:1). Ten (66.7%) patients have left sided lesion representing. Proptosis was the main presented manifestation in all patients. Complete tumor excision was done in 10 patients while incomplete excision was done in the rest of patients. Proptosis was improved post-operatively in patients presented by it: Ten (66.7%) patients had complete improvement while the other five (33.3%) patients improved significantly. No mortality occurred in our study. A mean follow-up period of 2.1 years (range: 4 months to 4 years), three (20%) patients have tumor recurrence. CONCLUSIONS: Total excision of Sphenoid meningioma enplaque carries difficulties and high rate of post-operative morbidity. Early detection with experienced neurosurgeons, microsurgical techniques and availability of high speed drill decrease the risk of post-operative morbidity. Reconstruction of dural and bone defect is very important regarding functional and cosmetic aspects.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180303
[Lr] Last revision date:180303
[St] Status:Publisher

  2 / 8028 MEDLINE  
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[PMID]: 29269071
[Au] Autor:Sebaaly A; Boubez G; Sunna T; Wang Z; Alam E; Christopoulos A; Shedid D
[Ad] Address:Department of Orthopedic Surgery, Centre Hopitalier de l'Université de Montréal, Montréal, Quebec, Canada; Faculty of Medicine, Saint Joseph University, Beirut, Lebanon. Electronic address: amersebaaly@hotmail.com.
[Ti] Title:Diffuse Idiopathic Hyperostosis Manifesting as Dysphagia and Bilateral Cord Paralysis: A Case Report and Literature Review.
[So] Source:World Neurosurg;111:79-85, 2018 Mar.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Diffuse idiopathic hyperostosis (DISH) is characterized by calcifications affecting mainly the spinal anterior longitudinal ligament. This disease is mainly asymptomatic but cervical osteophytes can sometimes cause dysphagia (DISHphagia), hoarseness, and even dyspnea. CASE DESCRIPTION: We report, for the first time in the medical literature, a case of a 76-year-old patient with DISH causing an important dysphagia as well as bilateral vocal cord paralysis causing critical dyspnea. The patient was surgically treated by anterior resection of the osteophytes and application of bone wax, with significant clinical improvement and no radiologic recurrence after 2 years of follow-up. DISCUSSION AND CONCLUSION: A thorough literature review didn't yield any article reporting on bilateral vocal cord paralysis caused by DISH. Management of this condition is typically multidisciplinary, and treatment of cervical osteophyte-associated dysphagia or respiratory compromise is primarily medical, after performing necessary tests to rule out other causes of dysphagia. Surgical intervention is warranted when medical treatment fails, when there is weight loss, a significant airway compromise or sleeping alterations. A treatment algorithm is proposed in the end of this review for symptomatic anterior osteophytes caused by DISH in the mobile cervical spine.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180303
[Lr] Last revision date:180303
[St] Status:In-Data-Review

  3 / 8028 MEDLINE  
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[PMID]: 29496215
[Au] Autor:Ventades NG; Laza IM; Hervella M; de-la-Rúa C
[Ad] Address:Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV-EHU), Barrio Sarriena s/n 48940, Leioa, Bizkaia, Spain. Electronic address: neregv21@gmail.com.
[Ti] Title:A recording form for differential diagnosis of arthropathies.
[So] Source:Int J Paleopathol;20:45-49, 2018 Mar.
[Is] ISSN:1879-9825
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:The present study is focused on a group of arthropathies that may have very similar bone manifestations (rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, psoriatic arthritis, osteoarthritis and diffuse idiopathic skeletal hyperostosis), which makes it more difficult to diagnose them in human remains from archaeological contexts. A stepwise recording form was designed in order to improve the identification and differential diagnosis of these pathological conditions in bone remains, particularly in joint manifestations of the spine, pelvis, hands, feet and other limb joints. This recording form was applied in the analysis of two medieval individuals from the Basque Country (Spain) who presented very severe arthropathic manifestations. The use of this recording form allowed the researchers the diagnosis of ankylosing spondylitis in one of them and diffuse idiopathic skeletal hyperostosis in the other.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[St] Status:In-Data-Review

  4 / 8028 MEDLINE  
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[PMID]: 29390344
[Au] Autor:Hsu SF; Lin CC
[Ad] Address:Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University Hospital.
[Ti] Title:Van Buchem disease: First case report in Taiwan.
[So] Source:Medicine (Baltimore);96(50):e9209, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Van Buchem disease (VBD) is a very rare autosomal recessive disease. According to our review of the relevant literature, this article is the first case report of VBD in Taiwan. PATIENT CONCERNS: A 54-year-old woman developed a protruding chin, frontal bossing, and macrocephaly at the age of 40 years. She noted the onset of progressive bilateral visual and hearing impairment at the age of 40 and 45 years, respectively. Intermittent headaches, peripheral facial palsy, recurrent bilateral trigeminal neuralgia, and back pain were also observed since age 40. DIAGNOSES: She received a diagnosis of VBD based on the phenotypic abnormalities of the skull and mandible, facial nerve involvement, radiological images of the skeleton, and her family history. INTERVENTIONS: She received symptomatic treatment and surgical decompression for spinal stenosis. OUTCOMES: Her clinical condition did not improve satisfactorily. LESSONS: We hope to promote clinician awareness of this very rare disease and its symptoms and signs. A comprehensive understanding of VBD might lead to the development of a curative therapy in the future.
[Mh] MeSH terms primary: Osteochondrodysplasias/diagnosis
Osteochondrodysplasias/therapy
[Mh] MeSH terms secundary: Decompression, Surgical
Diagnosis, Differential
Female
Humans
Middle Aged
Phenotype
Rare Diseases
Taiwan
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009209

  5 / 8028 MEDLINE  
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[PMID]: 29367531
[Au] Autor:Azuma K; Tamura M; Makino H; Sekiguchi M; Azuma N; Kitano M; Matsui K; Sano H
[Ad] Address:Division of Rheumatology, Department of Internal Medicine, Hyogo College of Medicine.
[Ti] Title:[A case of axial spondyloarthritis acute onset as opportunity tonsil foci infection].
[So] Source:Nihon Rinsho Meneki Gakkai Kaishi;40(6):460-466, 2017.
[Is] ISSN:1349-7413
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:  A 49-year-old female with a chief complaints of arthralgia, and a medical history is Hashimoto's disease presented to us. She had been previously treated for Sjögren's syndrome at our hospital. She had anterior chest and polyarticular pain. On admission, her blood test results were as follows: white blood cells, 12700/µl; C reactive protein, 24.8 mg/dl; erythrocyte sedimentation rate 122 mm/h, Anti-streptolysin O, 1179 IU/ml;an, ASK, 10240. She had tenderness in both her hand and finger joints, recurrent episodes of tonsillitis and pustular eruption. Her imaging studies were remarkable for inflammation of the sacroiliac joint and bone erosion of the hand joint, among other findings. We considered a diagnosis of either axial spondyloarthritis or synovitis acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome due to an opportunistic tonsillar infection. The differential diagnosis between axial spondyloarthritis or SAPHO syndrome is difficult to make. We discuss this case in the context of previous literature.
[Mh] MeSH terms primary: Opportunistic Infections/complications
Spondylarthritis/complications
Spondylarthritis/diagnosis
Tonsillitis/complications
[Mh] MeSH terms secundary: Acquired Hyperostosis Syndrome
Acute Disease
Diagnosis, Differential
Female
Humans
Middle Aged
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[Js] Journal subset:IM
[Da] Date of entry for processing:180126
[St] Status:MEDLINE
[do] DOI:10.2177/jsci.40.460

  6 / 8028 MEDLINE  
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[PMID]: 29482347
[Au] Autor:Slonimsky E; Lidar M; Stern M; Eshed I
[Ad] Address:1 Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer, Affiliated with the Sackler School of Medicine, Tel Aviv University, Israel.
[Ti] Title:Degenerative changes of the thoracic spine do exist in patients with diffuse idiopathic skeletal hyperostosis: a detailed thoracic spine CT analysis.
[So] Source:Acta Radiol;:284185118761205, 2018 Jan 01.
[Is] ISSN:1600-0455
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Background Degenerative intervertebral disease (DID) is an exclusion criterion in the Resnick and Niwayama radiographic classification for diffuse idiopathic skeletal hyperostosis (DISH). However, although DID was previously described in DISH, no systematic computed tomography (CT) analysis has been reported so far. Purpose To assess for the presence and prevalence of such changes on CT examinations of the thoracic spine of individuals with DISH. Material and Methods Intervertebral space (D1-L1) on chest CT examinations of DISH patients was retrospectively evaluated for the presence of DID. Parameters evaluated were disc space height, disc protrusion, subchondral cysts/sclerosis, Schmorl nodes, vacuum phenomenon, and posterior elements including costovertebral and facet joints. Parameters were compared with two age- and gender-matched control groups of individuals whose entire spine CT lacked evidence of DISH (Control 1 individuals < 2 flowing osteophytes, Control 2 individuals < 4 and ≥ 2 flowing osteophytes). Results A total of 158 participants (DISH/Control 1/Control 2 = 54/54/50; 106 men, 52 women; average age = 70.6 years) were evaluated. Average intervertebral disc height was significantly lower in the DISH group compared with both control groups (DISH/Control 1/Control 2 = 4.55/5.13/5.01 mm, P < 0.001). Costovertebral degenerative changes were more prevalent in DISH patients ( P < 0.05) and, except for vacuum phenomenon (more prevalent in controls), other DID changes were as prevalent in DISH as in controls. Conclusion The presence of degenerative intervertebral changes on thoracic CT should not deter from diagnosing DISH. Thus, the radiographic Resnick and Niwayama DISH criteria cannot be directly adapted to CT.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[St] Status:Publisher
[do] DOI:10.1177/0284185118761205

  7 / 8028 MEDLINE  
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[PMID]: 29481728
[Au] Autor:Martens HA; Boks SS
[Ad] Address:department of Rheumatology.
[Ti] Title:Diffuse idiopathic skeletal hyperostosis; on the wrong side?
[So] Source:Arthritis Rheumatol;, 2018 Feb 26.
[Is] ISSN:2326-5205
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A 58-year old man was referred to our rheumatology department because of arthralgia and generalized stiffness. His was already known with Kartagener syndrome with situs inversus. Physical examination revealed multiple painful enthesis and stiffness of the thoracic spine. There were no signs of arthritis. Diffuse idiopathic skeletal hyperostosis (DISH) was suspected. An x-ray of the thoracic spine revealed continuous ossification between five contiguous vertebral bodies (A). The lateral view showed extensive ossification of the anterior longitudinal ligament (B). The diagnosis of DISH was made. In DISH, the ossification is normally localized on the right side of the spine. It is hypothesized that the descending aorta inhibits ossification on the left side. In our patient, however, the ossification occurred on the left side. We concluded that along with the situs inversus due to Kartagener syndrome, the pathologic features of DISH had also "moved" to the contralateral side. This feature has rarely been reported in patients with DISH. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:Publisher
[do] DOI:10.1002/art.40465

  8 / 8028 MEDLINE  
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[PMID]: 29481381
[Au] Autor:Yamada K; Satoh S; Abe Y; Yanagibashi Y; Hyakumachi T; Masuda T
[Ad] Address:Department of Orthopaedic Surgery, Wajokai Eniwa Hospital, Eniwa, Hokkaido 061-1449, Japan.
[Ti] Title:Diffuse Idiopathic Skeletal Hyperostosis Extended to the Lumbar Segment is a Risk Factor of Reoperation in Patients Treated Surgically for Lumbar Stenosis.
[So] Source:Spine (Phila Pa 1976);, 2018 Feb 23.
[Is] ISSN:1528-1159
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:STUDY DESIGN: Retrospective longitudinal cohort study. OBJECTIVE: To investigate the association between diffuse idiopathic skeletal hyperostosis (DISH) and reoperation in patients treated surgically for lumbar spinal stenosis (LSS) in long-term results. SUMMARY OF BACKGROUND DATA: Few studies have evaluated DISH as a potential risk factor of poor surgical results for LSS. METHODS: This study included 1063 responders to a postoperative postal survey out of 2363 consecutive patients who underwent surgery for LSS between 2002 and 2010. The survey included questions about reoperations performed at another hospital and the patient-reported outcomes. DISH was evaluated by preoperative standing whole-spine radiographs. We investigated DISH as a predictor of reoperation and characteristics of poor outcomes in patients with DISH. We also assessed selection bias by examining the differences between responders and non-responders to a postal survey. RESULTS: Reoperations were performed in a total of 115 patients (10.8%) within an average of 8.6 years after the initial surgeries. Patients who only had DISH were not associated with reoperation; however, reoperations were performed significantly more often in patients with DISH extended to the lumbar segment (L-DISH) than in patients without (22% and 7.3%, respectively; p < 0.001). Cox analysis showed that L-DISH was one of the significant independent predictors for reoperation (hazard ratio 2.05, p = 0.009). Surgery-free survival was significantly shorter in patients with L-DISH than in those without (p = 0.005). The cause of reoperation did not differ between the patients with and without L-DISH. Several factors, but not L-DISH, were significantly associated with responders to the survey. CONCLUSIONS: L-DISH was independently associated with reoperation for LSS. The decreased number of lumbar mobile segments due to L-DISH might lead to unfavorable outcomes. Careful follow-up of patients is needed after surgery for LSS with L-DISH. LEVELS OF EVIDENCE: 3.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:Publisher
[do] DOI:10.1097/BRS.0000000000002618

  9 / 8028 MEDLINE  
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[PMID]: 29264888
[Au] Autor:Pietrzyk B; Smertka M; Chudek J
[Ad] Address:Department of Pathophysiology, Medical University of Silesia, Katowice, Poland.
[Ti] Title:Sclerostin: Intracellular mechanisms of action and its role in the pathogenesis of skeletal and vascular disorders.
[So] Source:Adv Clin Exp Med;26(8):1283-1291, 2017 Nov.
[Is] ISSN:1899-5276
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Sclerostin is a glycoprotein involved in the regulation of bone metabolism, exclusively secreted by osteocytes. It affects the activity of bone morphogenetic proteins (BMPs) and is an inhibitor of the Wnt/ß-catenin metabolic pathway in bone cells. Osteocytes reduce the release of sclerostin in response to mechanical stimuli acting on bone, and thus promote the activation of osteogenic pathway Wnt/ß-catenin in osteoblasts. This signaling pathway plays a key role in osteogenesis and bone turnover. Loss of sclerostin gene function is related to 3 different craniotubular hyperostosis processes: sclerosteosis, craniodiaphyseal dysplasia, and van Buchem disease. Additionally, experimental and clinical studies suggest that sclerostin may promote vascular calcification. Antibodies directed against sclerostin stimulate bone formation and represent a new therapeutic option in the treatment of diseases with increased bone resorption, such as osteoporosis and inflammatory diseases where there is generalized bone loss, periarticular osteoporosis, and cartilage damage, such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), and glucocorticoid-induced osteoporosis (GIO). Antibody use has the potential to offer new therapeutic approaches in the therapy of mineral and bone disorders resulting from chronic kidney disease (CKD-MBD) and vascular calcifications.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1712
[Cu] Class update date: 180227
[Lr] Last revision date:180227
[St] Status:In-Process
[do] DOI:10.17219/acem/68739

  10 / 8028 MEDLINE  
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[PMID]: 29478625
[Au] Autor:Sasagawa T; Nakamura T
[Ad] Address:Department of Orthopedics Surgery, Toyama Prefectural Central Hospital, Japan. Electronic address: sasagawawagasasa@yahoo.co.jp.
[Ti] Title:Traumatic spondyloptosis at the thoracolumbar junction in a patient with diffuse idiopathic skeletal hyperostosis: A case report.
[So] Source:J Orthop Sci;, 2018 Feb 22.
[Is] ISSN:1436-2023
[Cp] Country of publication:Japan
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:Publisher


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