Database : MEDLINE
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[PMID]: 29307504
[Au] Autor:How KN; Bhullar A
[Ad] Address:Dermatology Unit, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia. Electronic address: hkangnien@upm.edu.my.
[Ti] Title:The recurrent intertriginous rash.
[So] Source:Eur J Intern Med;, 2018 Jan 05.
[Is] ISSN:1879-0828
[Cp] Country of publication:Netherlands
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180108
[Lr] Last revision date:180108
[St] Status:Publisher

  2 / 430 MEDLINE  
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[PMID]: 28458435
[Au] Autor:Foti C; Romita P; Zanframundo G; Mastrolonardo M; Angelini G; Calogiuri G; Nettis E; Bonamonte D
[Ad] Address:Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy.
[Ti] Title:Ciprofloxacin induced acute generallised exanthematous pustulosis.
[So] Source:Indian J Pharmacol;49(1):119-120, 2017 Jan-Feb.
[Is] ISSN:1998-3751
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Acute generalized exanthematous pustulosis (AGEP) is an uncommon and self-limiting skin rash commonly caused by drugs and is characterized by the acute onset of fever, pustulosis, and neutrophilia from 4 to 10 days after the drug intake. We describe a case of AGEP in a 61-year-old woman that was hospitalized for the acute onset of fever, erythroderma, and pustulosis. Clinical history revealed that she had been treating a bacterial inguinal intertrigo for 4 days with ciprofloxacin 500 mg tablets twice daily and desloratadine 5 mg tablet once daily. To the best of our knowledge, this is the third reported case of AGEP caused by ciprofloxacin, supporting two other previous reports.
[Mh] MeSH terms primary: Acute Generalized Exanthematous Pustulosis/etiology
Anti-Bacterial Agents/adverse effects
Ciprofloxacin/adverse effects
Drug Eruptions/etiology
[Mh] MeSH terms secundary: Acute Generalized Exanthematous Pustulosis/pathology
Anti-Bacterial Agents/administration & dosage
Ciprofloxacin/administration & dosage
Drug Eruptions/pathology
Female
Fever/etiology
Humans
Intertrigo/drug therapy
Loratadine/administration & dosage
Loratadine/analogs & derivatives
Middle Aged
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Bacterial Agents); 5E8K9I0O4U (Ciprofloxacin); 7AJO3BO7QN (Loratadine); FVF865388R (desloratadine)
[Em] Entry month:1712
[Cu] Class update date: 171229
[Lr] Last revision date:171229
[Js] Journal subset:IM
[Da] Date of entry for processing:170502
[St] Status:MEDLINE
[do] DOI:10.4103/0253-7613.201014

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[PMID]: 29150768
[Au] Autor:Nazzaro G; Tourlaki A; Scoppio B; Restelli A; Grancini A; Brambilla L
[Ad] Address:Dermatology Unit, I.R.C.C.S. Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. gianluca.nazzaro@gmail.com.
[Ti] Title:Toe web intertrigo in Kaposi's sarcoma patients: a microbiological study in a large cohort of patients.
[So] Source:Eur J Clin Microbiol Infect Dis;, 2017 Nov 17.
[Is] ISSN:1435-4373
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Kaposi 's sarcoma (KS) is a rare multifocal angioproliferative disease associated with human herpes virus 8 (HHV-8) infection, characterized by cutaneous nodules or plaques especially on the lower limbs. Some skin modifications, such as chronic lymphedema, plantar hyperkeratosis and interdigital desquamation, may be associated with consequent impairment of the local immunosurveillance and increased risk of some bacterial or mycotic infections. With the objective of evaluating if bacterial or mycotic infections in KS patients are supported by different microorganisms compared to control patients, we performed an observational retrospective study, comparing positive cultural swabs of interdigital intertrigo of KS patients with positive cultural swabs of interdigital intertrigo of patients admitted to our dermatologic unit during the last 10 years. One hundred KS patients and 84 control patients were admitted to this study. Some of the skin swabs from interdigital spaces were positive for more than one microorganism, and therefore we found 187 microorganisms among the KS group and 182 microorganisms in the control group. The most common microrganisms among KS patients were T. mentagrophytes (16%), S. aureus (14.9%), P. aeruginosa (13.9%), S. marcescens (5,9%), while among non-KS patients were S. aureus (26,9%), C. albicans (22%), S. agalactiae (7.7%) and E. coli (9.9%). These differences are statistically significant (p < 0.01). KS patients may be more affected by toe web intertrigo due to other bacteria and dermatophytes than the general population. During clinical examination, a careful inspection is necessary for an early diagnosis of toe web intertrigo, in order to prevent serious complications, such as cellulitis and sepsis. Consequently, a cultural examination with antibiogram is required to identify the causative agent of intertrigo and guide antimicrobial therapy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171118
[Lr] Last revision date:171118
[St] Status:Publisher
[do] DOI:10.1007/s10096-017-3132-3

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[PMID]: 29132795
[Au] Autor:Diongue K; Diallo MA; Ndiaye M; Seck MC; Badiane AS; Ndiaye D
[Ad] Address:Laboratoire de parasitologie-mycologie, CHU Aristide-Le-Dantec, BP 16477, Dakar, Sénégal; Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontologie, université Cheikh-Anta-Diop, BP 5005, Dakar, Sénégal. Electronic address: khadimase@gmail.com.
[Ti] Title:Les intertrigos interorteils impliquant Fusarium spp. à Dakar (Sénégal). [Interdigital tinea pedis resulting from Fusarium spp. in Dakar, Senegal].
[So] Source:J Mycol Med;, 2017 Nov 10.
[Is] ISSN:1773-0449
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:INTRODUCTION: Fungal interdigital tinea pedis (ITP) is a common pathology mainly due to dermatophytes and yeasts. Fusarium sp. is rarely incriminated in the genesis of intertrigo. In Dakar, a recent study conducted in 2016 on fungal ITP showed that Fusarium were more involved in the etiology of ITP than dermatophytes, coming just after yeasts dominated by Candida. Following this, we wanted to draw attention to the increasing incidence of ITP resulting from Fusarium spp., in Dakar, Senegal, and to analyze the epidemiological and mycological particularities of these ITP due to Fusarium spp. PATIENTS AND METHODS: A retrospective study including all patients received at the laboratory for suspicion of ITP between January 1st, 2014 and June 30th, 2017 was conducted. Diagnosis was based on mycological examination, including direct examination and culture. Mycological analysis was considered positive when direct examination and culture were positive after at least one repeat. RESULTS: Twenty-nine cases of Fusarium ITP accounting for 44.6% of all ITP in the study period were diagnosed in 15 men and 14 women. The mean age of the patients was 48.4 years. Fusarium ITP were diagnosed in immunocompetent patients except in two diabetics. The mean duration of the lesions was 6.83 years. The most frequent species isolated belonged to the Fusarium solani complex with 19 cases. CONCLUSION: Fusarium ITP in a healthy subject requires regular monitoring because any subsequent decrease in immune defenses could lead to fatal hematogenous spread.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171114
[Lr] Last revision date:171114
[St] Status:Publisher

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[PMID]: 29103724
[Au] Autor:Ekman L; Nyman AK; Landin H; Magnusson U; Waller KP
[Ad] Address:Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute, SE-75189, Uppsala, Sweden; Department of Clinical Sciences, Swedish University of Agricultural Sciences, SE-75007, Uppsala, Sweden.
[Ti] Title:Mild and severe udder cleft dermatitis-Prevalence and risk factors in Swedish dairy herds.
[So] Source:J Dairy Sci;, 2017 Nov 02.
[Is] ISSN:1525-3198
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Udder cleft dermatitis (UCD) is an inflammatory skin condition affecting the anterior parts of the udder of dairy cows. The lesions may present as mild or severe skin lesions and have been associated with mastitis and digital dermatitis. The full etiology and pathogenesis are not understood and no large-scale studies have investigated prevalence and risk factors. Therefore, the main objectives of the study were to investigate the prevalence of mild and severe UCD in Swedish dairy herds and to identify risk factors associated with such lesions. We also wanted to investigate risk factors for all cases of UCD and to determine whether UCD increases the risk for mastitis and culling. A random sample of 100 freestall dairy herds were included in the study, and each herd was visited once. Cows were registered as having no, mild, or severe UCD. Additional cow and herd data were obtained via observations, interviews, and the Swedish Official Milk Recording Scheme. The data were analyzed using logistic regression models to identify risk factors for mild and severe UCD. In total, data from 3,479 cows in 99 herds were analyzed. The prevalence of mild and severe UCD was 19 and 9%, respectively. Lesions were found in 98 of 99 herds but the within-herd prevalence of mild (0-43%) and severe (0-33%) UCD varied notably between herds. Breed (Swedish Red compared with Swedish Holstein), certain udder conformation traits, and higher parity were risk factors associated with increased risk of UCD. In addition, cows with hock lesions and cows in herds with high incidence of culling due to hoof and leg diseases had a higher risk for mild UCD. More days in milk and high milk yield were cow-related risk factors associated with severe UCD. Three housing-related factors (shorter cubicles, mattress as cubicle base, and cubicles installed before 2001 compared with 2001-2005), a high incidence of veterinary-treated clinical mastitis and culling due to udder diseases, and a low incidence of culling of first-parity cows in early lactation were herd-related risk factors associated with increased risk for severe UCD. In addition, cows in herds with a high proportion of heifers older than 17 mo that were not inseminated were associated with lower risk of all UCD. Finally, UCD was not associated with the outcomes milk somatic cell count, veterinary-treated clinical mastitis, or culling in the multivariable analyses. The etiology of UCD is most likely multifactorial, involving udder conformation traits and other cow-related risk factors as well as herd-related risk factors. The high prevalence of severe UCD lesions in Swedish dairy cows emphasizes the need for preventive measures and efficient treatments.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171106
[Lr] Last revision date:171106
[St] Status:Publisher

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[PMID]: 29042226
[Au] Autor:Zawar V; Pawar M; Reddy RR; Chuh A
[Ad] Address:Nashik District Maratha Vidya Prasarak Samaj Medical College, Nashik, India.
[Ti] Title:Liquid nitrogen cryotherapy for chronic recalcitrant interdigital candidiasis of toe-spaces - an uncontrolled pilot study.
[So] Source:J Am Acad Dermatol;, 2017 Oct 14.
[Is] ISSN:1097-6787
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171018
[Lr] Last revision date:171018
[St] Status:Publisher

  7 / 430 MEDLINE  
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[PMID]: 29017215
[Au] Autor:Schuh T; Stöllberger C
[Ti] Title:Pulmonalembolie trotz Rivaroxaban bei einer adipösen Patientin. [Pulmonary Embolism Despite Rivaroxaban in an Obese Patient].
[So] Source:Dtsch Med Wochenschr;142(20):1548-1551, 2017 Oct.
[Is] ISSN:1439-4413
[Cp] Country of publication:Germany
[La] Language:ger
[Ab] Abstract:Rivaroxaban, an oral factor Xa inhibitor, is approved for therapy of venous thromboembolism. It is unclear whether the standard dose for patients with a body mass index (BMI) > 40 kg/m is sufficient. The 45-year-old patient was admitted because of increasing respiratory distress. She had a history of pulmonary embolism 30 months before the admission, a factor V Leiden mutation and several hospitalisations due to dermatomycoses. The patient briefly took phenprocoumon which was changed to 20 mg rivaroxaban due to a lack of adherence. Six months before admission, the patient paused the rivaroxaban therapy because of dental surgery and suffered a recurrent pulmonary embolism. The patient presented with increasing difficulty of breathing, morbid obesity with a BMI of 59.3 kg/m and intertrigo of the lower extremities. The ECG showed a right axis deviation, a pulmonary P-wave and an incomplete right bundle branch block. Computed tomography showed pulmonary embolisms of the left lower lobe. The pulmonary artery was dilated, and the right atrium was enlarged. Venous thrombosis of the lower limb could not be certainly ruled out. The D-dimer was elevated with 5.895 mg/L (normal value up to 169 mg/L) and NT-pro-BNP was elevated at 5.580 ng/L (normal value up to 0.5 ng/L). Sixteen hours after the onset of symptoms, 22 hours after the last dose, the serum rivaroxaban level was 137 ng/ml. According to manufacturers, the therapeutic range of rivaroxaban after 2 - 4 hours is 22 - 535 ng/ml, and after 24 hours 6 - 239 ng/ml. After initiation of a therapy with low-molecular weight heparin and subsequent oral anticoagulation with phenprocoumon, the symptoms decreased. It is highly probable that the pulmonary embolism occurred at a time when the rivaroxaban level was in the therapeutic range. Since there are only few data about safety and efficacy of rivaroxaban and other non-vitamin K-oral anticoagulants (NOACs) in severely obese patients, the recommendations of the "International Society for Thrombosis and Haemostasis" should be followed: Rivaroxaban and other NOACs should not be used in patients with a BMI > 40 kg/m or weight > 120 kg, since only few data on this patient group are available. If NOACs are necessary in these patients, serum concentrations of NOACs should be measured.
[Mh] MeSH terms primary: Obesity, Morbid/complications
Pulmonary Embolism/etiology
Rivaroxaban/adverse effects
Rivaroxaban/therapeutic use
Substance Withdrawal Syndrome/etiology
Venous Thromboembolism/complications
Venous Thromboembolism/drug therapy
[Mh] MeSH terms secundary: Activated Protein C Resistance/complications
Activated Protein C Resistance/drug therapy
Contraindications
Dose-Response Relationship, Drug
Drug Substitution
Female
Fibrin Fibrinogen Degradation Products/metabolism
Heparin, Low-Molecular-Weight/therapeutic use
Humans
Middle Aged
Phenprocoumon/therapeutic use
Pulmonary Embolism/diagnostic imaging
Pulmonary Embolism/drug therapy
Recurrence
Surgery, Oral
Tomography, X-Ray Computed
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Fibrin Fibrinogen Degradation Products); 0 (Heparin, Low-Molecular-Weight); 0 (fibrin fragment D); 9NDF7JZ4M3 (Rivaroxaban); Q08SIO485D (Phenprocoumon)
[Em] Entry month:1710
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:171011
[St] Status:MEDLINE
[do] DOI:10.1055/s-0043-114547

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[PMID]: 28778416
[Au] Autor:Morand A; Morand JJ
[Ad] Address:Service de spécialités pédiatriques et de médecine infantile, hôpital de la Timone, CHU de Marseille, 264, rue Saint-Pierre, 13385 Marseille cedex 05, France.
[Ti] Title:Pseudomonas aeruginosa en dermatologie. [Pseudomonas aeruginosa in dermatology].
[So] Source:Ann Dermatol Venereol;144(11):666-675, 2017 Nov.
[Is] ISSN:0151-9638
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:Pseudomonas aeruginosa, a ubiquitous Gram-negative bacillus characterized by its greenish color and sweetish smell, is at the origin of potentially severe forms of dermatosis, such as ecthyma gangrenosum which marks immunosuppression or reveals blood-poisoning, especially in children. It frequently colonizes chronic wounds and serious burns, and spongiotic or acantholytic dermatosis, especially when severe or localized in skinfolds. It requires special care because of its high resistance to antibiotics and antiseptics. It can also involve folliculitis favored by water sports or a nail disorder (chloronychia).
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 171027
[Lr] Last revision date:171027
[St] Status:In-Process

  9 / 430 MEDLINE  
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[PMID]: 28731866
[Au] Autor:Imam TH; Cassarino D; Patail H; Khan N
[Ad] Address:*Department of Medicine, Fontana Medical Center, Southern California Permanente Medical Group Fontana, CA;†Department of Pathology, Sunset Medical Center, Southern California Permanente Medical Group, Los Angeles, CA; and‡Internal Medicine Residency Program, State University, NY, Downstate, Brooklyn, NY.
[Ti] Title:Refractory Intertrigo in the Right Inguinal Crease: Answer.
[So] Source:Am J Dermatopathol;39(8):e104-e105, 2017 Aug.
[Is] ISSN:1533-0311
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 170721
[Lr] Last revision date:170721
[St] Status:In-Data-Review
[do] DOI:10.1097/DAD.0000000000000545

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[PMID]: 28727599
[Au] Autor:Imam TH; Cassarino D; Patail H; Khan N
[Ad] Address:*Department of Medicine, Southern California Permanente Medical Group, Fontana Medical Center, Fontana, CA; †Department of Pathology, Southern California Permanente Medical Group, Sunset Medical Center, Los Angeles, CA; and ‡Internal Medicine Residency Program, State University New York, Downstate, Brooklyn, NY.
[Ti] Title:Refractory Intertrigo in the Right Inguinal Crease: Challenge.
[So] Source:Am J Dermatopathol;39(8):629, 2017 Aug.
[Is] ISSN:1533-0311
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 170720
[Lr] Last revision date:170720
[St] Status:In-Data-Review
[do] DOI:10.1097/DAD.0000000000000544


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