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[PMID]: 29518300
[Au] Autor:Carriedo-Rico EG; García-Morato-Jorreto P
[Ad] Address:Hospital Ángeles Lomas y Hospital Ángeles Metropolitano. Ciudad de México. México.
[Ti] Title:Lipoma gigante de muslo. Reporte de un caso. [Giant lipoma of the thigh. Case report].
[So] Source:Acta Ortop Mex;31(5):248-251, 2017 Sep-Oct.
[Is] ISSN:2306-4102
[Cp] Country of publication:Mexico
[La] Language:spa
[Ab] Abstract:Lipoma is a tumor of adipose tissue cells that can develop in any part of the body; We present the case of an 86-year-old woman with a lesion of the left thigh as well as her diagnostic approach, specific surgical treatment and histopathological analysis. Three years after its resection, the function of the lower extremity was preserved.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review

  2 / 12641 MEDLINE  
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[PMID]: 29271127
[Au] Autor:Longo M; Bavcar S; Handel I; Smith S; Liuti T
[Ad] Address:Royal (Dick) School of Veterinary Studies and Roslin Institute, The University of Edinburgh, Roslin, EH25 9RG, UK.
[Ti] Title:Real-time elastosonography of lipomatous vs. malignant subcutaneous neoplasms in dogs: Preliminary results.
[So] Source:Vet Radiol Ultrasound;59(2):198-202, 2018 Mar.
[Is] ISSN:1740-8261
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Real-time elastography is a recently introduced ultrasound technique allowing the investigation of elastic properties of tissues. A diagnostic accuracy study was conducted to test the performance of this technique in the assessment of subcutaneous lesions in dogs. Fifty-two dogs were prospectively included in the preliminary study (34 malignant and 18 benign lesions). B-mode ultrasound was performed assessing the shape, margins, heterogeneity, and echotexture of the lesions. On elastosonography, assessment of the percentage of softness/hardness was recorded. A qualitative assessment was performed according to the Tsukuba elasticity score with a 1-5 score, representing the increased percentage of high stiffness areas. Results were compared with cytology/histopathology of the lesions. Receiver Operating Curves of the overall diagnostic sensitivity and specificity were obtained. Fisher's exact test and Pearsons's Chi-squared test estimated the relationship between the B-mode appearance of the lesions and final diagnosis. A hardness cutoff of 50.25% was identified between lesions, with malignant neoplasms having higher percentages. A 100% specificity and 89% sensitivity for correctly detecting the nature of the lesion on elastosonography was established. Qualitative assessment of the Tsukuba elasticity score established 1.5 as the cutoff between elastograms of lipomatous and malignant lesions, with 100% sensitivity and 61% specificity in differentiating them. Real-time elastosonography is a novel, noninvasive, and accurate technique for differentiating malignant from benign lipomatous lesions in dogs. This method could be considered as a complementary tool with additional diagnostic value for routine invasive procedures, such as fine needle aspirates.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process
[do] DOI:10.1111/vru.12588

  3 / 12641 MEDLINE  
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[PMID]: 29517205
[Au] Autor:Harazin-Lechowska A; Ambroziak-Lackowska B; Rys J; Kruczak A; Gruchala A; Jaszcz-Gruchala A; Danda D; Przewoznik M; Halaszka K
[Ti] Title:The role of histology, grading, location of tumour and ploidy in evaluation of outcome in patients with liposarcoma.
[So] Source:Pol J Pathol;68(4):343-351, 2017.
[Is] ISSN:1233-9687
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Department of Tumour Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Kraków, Poland The review of literature indicates that several clinico-morphological factors such as location of the primary tumour as well as its size, histologic subtype, and grade or even selected molecular changes may significantly affect survival of liposarcoma (LPS) patients. Data concerning prognostic importance of DNA ploidy status in LPS cells are extremely limited and results of flow cytometry (FCM) studies have never been compiled with the current classification of malignant adipocytic tumours. Based on evaluation of material from 54 liposarcomas which was available for both histological and FCM analysis, we distinguished four prognostic groups of patients. The best prognosis was noticed for diploid and grade G1 well-differentiated or myxoid liposarcomas localised on extremities. None of the patients with lipoma-like WDLPS and myxoid liposarcoma grade 1 metastasised, while metastases were observed among patients with dedifferentiated LPS (70% of 5-year MFS) and cellular myxoid or round cell liposarcoma (20% of 5-year MFS, only). The metastasis-free survival curves for the above mentioned groups of patients differed significantly (p = 0.00001).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review

  4 / 12641 MEDLINE  
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[PMID]: 29516960
[Au] Autor:Li X; Gui Y; Shen F; Zhao CL; Yang Y; Han W
[Ad] Address:Department of Endoscopy, Xinxiang Central Hospital, Henan Province, PR China.
[Ti] Title:The application value of capsule endoscopy in diagnosing small intestinal carcinoma.
[So] Source:J Cancer Res Ther;14(1):57-60, 2018 Jan.
[Is] ISSN:1998-4138
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Objective: The aim of this study was to explore the clinical value of capsule endoscopy in the diagnosis of small intestine neoplastic lesions. Materials and Methods: A retrospective analysis was conducted on the clinical data of 108 patients who underwent capsule endoscopic examination in the Endoscopy Center of Xinxiang Central Hospital from February 2010 to January 2014. The characteristics of different small bowel diseases were observed, and the prevalence rates of different small bowel lesions were calculated. Results: Of the included 108 patients who received capsule endoscopic examination, 74 cases showed lesions, with a detection rate of 68.52%. Of these 74 patients, 56 cases (51.85%) suffered from small bowel diseases and 18 cases (16.67%) were manifested with other gastrointestinal lesions. Moreover, obvious lesion was not observed in 34 cases (31.48%). Among the patients with lesions, we observed seven cases of submucosal tumor in small intestines, five cases of small intestinal carcinoma, two cases of small intestinal polyps, two cases of small intestinal roundworm, eight cases of small intestine ulcer, one case of Crohn's disease, 18 cases of enteritis, two cases of small intestine diverticula, four cases of small intestine hemangioma, one case of small intestine vascular malformation, one case of intestinal lymphangiectasia, one case of small intestine compression, two cases of small intestine hemorrhage, and two cases of small intestinal lipoma. Among the patients who showed other gastrointestinal lesions, we observed one case of esophageal diverticula, three cases of gastric erosion, six cases of superficial gastritis, four cases of gastric ulcer, one case of pyloric ulcer, one case of colonic polyps, and two cases of colon tumor. Conclusion: Capsule endoscopy demonstrated a high diagnostic value for various small bowel diseases, including both tumor and inflammatory lesions. Given its simplicity, safety, and reliability, capsule endoscopy was an important examination tool for the diagnosis of small bowel diseases.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.4103/jcrt.JCRT_584_17

  5 / 12641 MEDLINE  
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[PMID]: 29510213
[Au] Autor:Zimmer V
[Ad] Address:Department of Medicine, Marienhausklinik St. Josef Kohlhof, Neunkirchen, Germany; Department of Medicine II, Saarland University Medical Center, Saarland University Homburg, Germany. Electronic address: vincent.zimmer@gmx.de.
[Ti] Title:The naked fat sign: a signature finding in colonic lipoma.
[So] Source:Clin Gastroenterol Hepatol;, 2018 Mar 03.
[Is] ISSN:1542-7714
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher

  6 / 12641 MEDLINE  
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[PMID]: 29503824
[Au] Autor:Cannavale G; Francone M; Galea N; Vullo F; Molisso A; Carbone I; Catalano C
[Ad] Address:Department of Radiological, Oncological and Anatomo-Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
[Ti] Title:Fatty Images of the Heart: Spectrum of Normal and Pathological Findings by Computed Tomography and Cardiac Magnetic Resonance Imaging.
[So] Source:Biomed Res Int;2018:5610347, 2018.
[Is] ISSN:2314-6141
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Ectopic cardiac fatty images are not rarely detected incidentally by computed tomography and cardiac magnetic resonance, or by exams focused on the heart as in general thoracic imaging evaluations. A correct interpretation of these findings is essential in order to recognize their normal or pathological meaning, focusing on the eventually associated clinical implications. The development of techniques such as computed tomography and cardiac magnetic resonance allowed a detailed detection and evaluation of adipose tissue within the heart. This pictorial review illustrates the most common characteristics of cardiac fatty images by computed tomography and cardiac magnetic resonance, in a spectrum of normal and pathological conditions ranging from physiological adipose images to diseases presenting with cardiac fatty foci. Physiologic intramyocardial adipose tissue may normally be present in healthy adults, being not related to cardiac affections and without any clinical consequence. However cardiac fatty images may also be the expression of various diseases, comprehending arrhythmogenic right ventricular dysplasia, postmyocardial infarction lipomatous metaplasia, dilated cardiomyopathy, and lipomatous hypertrophy of the interatrial septum. Fatty neoplasms of the heart as lipoma and liposarcoma are also described.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.1155/2018/5610347

  7 / 12641 MEDLINE  
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[PMID]: 29429160
[Au] Autor:Zhao M; Wang YB; Yan YJ; Wang W; Ru GQ; He XL
[Ad] Address:Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
[Ti] Title:[Clinicopathologic features of atypical spindle cell lipomatous tumor].
[So] Source:Zhonghua Bing Li Xue Za Zhi;47(2):99-104, 2018 Feb 08.
[Is] ISSN:0529-5807
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To investigate the clinicopathologic characteristics, immunophenotype, differential and diagnostic features of atypical spindle cell lipomatous tumor (ASLT). Three cases of ASLT were collected from January 2010 to March 2017 at Zhejiang Provincial People's Hospital. The clinical and imaging features, histomorphology, immunophenotype and prognosis were analyzed. Fluorescence in situ hybridization (FISH) was used to detect MDM2 gene amplification, and relevant literature was reviewed. All three patients were adult males, aged 38, 43 and 54 years, respectively. One tumor originated in the subcutaneous soft tissue in the head and neck, one was located in the left primary bronchus and one in the latissimus dorsi muscle. Grossly, all three tumors were circumscribed and ranged from 4.0 to 5.8 cm in size. Microscopically, all showed a focally infiltrative front. These tumors were composed of variable proportions of spindle-shaped and adipocytic cells in a background of variable fibrous and edematous matrix. Scattered lipoblasts were easily seen. One tumor was composed predominately of spindle tumor cells, one of adipocytic cells, and one of equally mixed cell populations. The spindle tumor cells were generally bland-appearing with focal nuclear enlargement and hyperchromasia noted in one case. Mitosis was not seen in neither the spindle cells nor the adipocytic cells. By immunohistochemistry, diffuse and strong reactivity to CD34 of the spindle cells was noted in all cases, definite loss of Rb expression was noted in one of three cases, and S-100 protein was expressed only in the adipocytic cells. INI-1 was intact and Ki-67 index was 1% to 3%. All other markers including CDK4, MDM2, STAT6, SOX10, CD99, bcl-2, ß-catenin, CD117, GFAP, CK, EMA, SMA and desmin were negative. FISH of MDM2 was done in two cases, and both showed no amplification. The ASLT in the head and neck had two recurrences during 17 months of follow-up, whereas the tumor in the latissimus dorsi was free of disease during 33 months of follow-up. ASLT is a rare subtype of low-grade adipocytic neoplasm and is distinctive from atypical lipomatous tumor/well-differentiated liposarcoma. The histomorpholgy of ASLT has significant heterogeneity and forms a continuous spectrum. ASLT needs to be distinguished from a series of benign and malignant soft tissue tumors.
[Mh] MeSH terms primary: Bronchial Neoplasms/pathology
Head and Neck Neoplasms/pathology
Lipoma/pathology
Muscle Neoplasms/pathology
[Mh] MeSH terms secundary: Adult
Bronchial Neoplasms/chemistry
Head and Neck Neoplasms/chemistry
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Lipoma/chemistry
Liposarcoma/chemistry
Liposarcoma/pathology
Male
Middle Aged
Muscle Neoplasms/chemistry
Neoplasm Recurrence, Local
S100 Proteins/analysis
STAT6 Transcription Factor/analysis
Superficial Back Muscles
beta Catenin/analysis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (CTNNB1 protein, human); 0 (S100 Proteins); 0 (STAT6 Transcription Factor); 0 (STAT6 protein, human); 0 (beta Catenin)
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0529-5807.2018.02.004

  8 / 12641 MEDLINE  
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[PMID]: 29381623
[Au] Autor:Hakeem AH; Hakeem IH; Budharapu A; Wani FJ
[Ad] Address:Department of Head and Neck Oncology, Apollo Cancer Institute, Hyderabad, India.
[Ti] Title:Giant Parapharyngeal Space Lipoma Extending to the Pterygoid Region (Anterior Skull Base).
[So] Source:J Craniofac Surg;29(2):e149-e150, 2018 Mar.
[Is] ISSN:1536-3732
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Although lipoma is frequently seen in the head and neck region, but occurrence of the lipoma in the parapharyngeal space is rare. It is extremely rare for a parapharyngeal lipoma to extent to the pterygoid region (ie, anterior skull base). Management of giant parapharyngeal space lipoma with skull base extension and proximity to the vital neurovascular structures poses a challenge to surgeon. The authors report a patient with giant lipoma extending from the upper border of the clavicle to the pterygoid region. Complete excision was done using upper transverse cervical incision and pterygoid region was approached after removal of the ipsilateral submandibular gland. Surgery produced excellent cosmetic results with no functional impairment.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Process
[do] DOI:10.1097/SCS.0000000000004384

  9 / 12641 MEDLINE  
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[PMID]: 29256430
[Au] Autor:Stimmelmayr R; Rotstein D; Seguel M; Gottdenker N
[Ad] Address:North Slope Borough Department of Wildlife Management, Barrow, Alaska 99723, USA.
[Ti] Title:Hepatic lipomas and myelolipomas in subsistence-harvested bowhead whales Balaena mysticetus, Alaska (USA): a case review 1980-2016.
[So] Source:Dis Aquat Organ;127(1):71-74, 2017 Dec 19.
[Is] ISSN:0177-5103
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:We describe a case series of benign hepatic fatty tumors in 10 subsistence-harvested bowhead whales. Microscopic features included lipomatous and myelolipomatous masses. Extensive atrophy and/or destruction of hepatic parenchyma was not observed. No other significant disease was present except in an animal with unrelated chronic pleuritis. Based on our longitudinal case series (1980-2016) which identified 1-2 hepatic lipomas and myelolipomas in landed whales annually at Barrow, Alaska (USA), since 2012, hepatic lipomas and myelolipomas are occasionally seen in hunter-harvested bowhead whales. A conservative estimate for the percentage of bowhead whales with hepatic fatty tumors in landed whales in Barrow from 2012 to 2016 was 6% (7/111). The pathogenesis and exact cell origin of these benign fatty tumors in bowhead whales is undetermined. Assessment of further cases is warranted to better define the tissue distribution and pathogenesis of these tumors in bowhead whale liver.
[Mh] MeSH terms primary: Lipoma/veterinary
Liver Neoplasms/veterinary
Myelolipoma/veterinary
Whales
[Mh] MeSH terms secundary: Alaska
Animals
Female
Lipoma/epidemiology
Lipoma/pathology
Liver Neoplasms/epidemiology
Male
Myelolipoma/epidemiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[Js] Journal subset:IM
[Da] Date of entry for processing:171220
[St] Status:MEDLINE
[do] DOI:10.3354/dao03186

  10 / 12641 MEDLINE  
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[PMID]: 29500484
[Au] Autor:Kalia V; Daher O; Garvin G; Chhibber S; Shepherd J
[Ad] Address:Department of Radiology, St. Joseph Hospital, London, ON, N6A 4V2, Canada. v2k1978@gmail.com.
[Ti] Title:Synchronous bilateral lipoma arborescens of bicipitoradial bursa-a rare entity.
[So] Source:Skeletal Radiol;, 2018 Mar 02.
[Is] ISSN:1432-2161
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Lipoma arborescens is a rare non-neoplastic condition that affects the synovial lining of joints and bursae accounting for less than 1% of all lipomatous lesions. Characterized by villous proliferation of the synovium, it is an uncommon cause of intra/periarticular mass presenting as a painless, slowly progressive longstanding swelling, and is sometimes accompanied by intermittent monoarticular effusions. We describe a rare case of bilateral lipoma arborescens in the bicipitoradial bursae in a young male referred for MRI evaluation of spontaneous bilateral elbow swelling. We chose to bring this case to light because of the rare simultaneous involvement of the bicipitoradial bursae bilaterally and the role of MR in providing a definite diagnosis, hence obviating the need for biopsy and avoiding consideration of other complex intra/periarticular masses.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180303
[Lr] Last revision date:180303
[St] Status:Publisher
[do] DOI:10.1007/s00256-018-2915-7


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