Database : MEDLINE
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[PMID]: 23876586
[Au] Autor:Toepfer NJ; Baylor K; Henry Y; Simmons J; Berger PB
[Ad] Address:Department of Urology, Cardiovascular Center for Clinical Research, Geisinger Clinic, Danville, PA. Electronic address: njtoepfer@geisinger.edu.
[Ti] Title:The effect of antiplatelet and anticoagulant therapy on the clinical outcome of patients undergoing ureteroscopy.
[So] Source:Urology;82(4):773-9, 2013 Oct.
[Is] ISSN:1527-9995
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To determine if there is any difference in the clinical outcome for patients receiving aspirin, clopidogrel, and warfarin undergoing ureteroscopy and laser lithotripsy for urolithiasis compared with patients on no antithrombotic medication. METHODS: We retrospectively reviewed patients who underwent ureteroscopy for urolithaisis from July 1, 2005 to October 1, 2010. If patients continued aspirin, clopidogrel, or warfarin within 48 hours of surgery, they were considered to be on antithrombotic therapy. Patients not on these medications or those who discontinued the medications atleast 5 days before surgery comprised the control group. Six hundred forty-six patients met our inclusion criteria for analysis including 137 on aspirin alone, 17 on clopidogrel, 22 on warfarin, and 470 in the control group. RESULTS: Patients on antiplatelet and anticoagulants were older and were more likely to have risk factors for thromboembolism. When comparing patients on aspirin, clopidogrel, or warfarin with patients not on these medications, there was no difference in bleeding complications or need for an unplanned repeat ureteroscopy. There was also no difference in complications within 30 days of surgery. CONCLUSION: Among patients undergoing elective ureteroscopy and laser lithotripsy on the antithrombotic medications aspirin, clopidogrel, and warfarin, the procedure was as successful, and complications were not increased, compared with patients on no antithrombotic medications.
[Mh] MeSH terms primary: Anticoagulants/therapeutic use
Aspirin/therapeutic use
Lithotripsy, Laser
Platelet Aggregation Inhibitors/therapeutic use
Ticlopidine/analogs & derivatives
Ureteroscopy
Urolithiasis/diagnosis
Warfarin/therapeutic use
[Mh] MeSH terms secundary: Aged
Female
Humans
Male
Middle Aged
Retrospective Studies
Ticlopidine/therapeutic use
Treatment Outcome
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Anticoagulants); 0 (Platelet Aggregation Inhibitors); 5Q7ZVV76EI (Warfarin); A74586SNO7 (clopidogrel); OM90ZUW7M1 (Ticlopidine); R16CO5Y76E (Aspirin)
[Em] Entry month:1311
[Cu] Class update date: 140715
[Lr] Last revision date:140715
[Js] Journal subset:IM
[Da] Date of entry for processing:130930
[St] Status:MEDLINE

  2 / 5656 MEDLINE  
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[PMID]: 25017280
[Au] Autor:Lee CC; Chao AS; Chang YL; Peng HH; Wang TH; Chao A
[Ad] Address:Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan....
[Ti] Title:Acute pancreatitis secondary to primary hyperparathyroidism in a postpartum patient: A case report and literature review.
[So] Source:Taiwan J Obstet Gynecol;53(2):252-5, 2014 Jun.
[Is] ISSN:1875-6263
[Cp] Country of publication:China (Republic : 1949- )
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Primary hyperparathyroidism (PHPT) is a rare clinical entity in reproductive women. Unusual hypercalcemia causing pancreatitis in the peripartum period carries significant morbidity to both the fetus and the mother. CASE REPORT: A 38-year-old woman developed a morbid course of intractable intra-abdominal abscess by pancreatitis, hydronephrosis by renal lithiasis, and unusual neurological presentations soon after delivery. Serial serum calcium level and imaging studies lead to the final diagnosis of PHPT due to a parathyroid adenoma. Data on 14 patients who suffered from pancreatitis due to hyperparathyroidism were collected from a MEDLINE search. The reasons for delayed diagnosis and literature review of acute pancreatitis in PHPT are discussed. CONCLUSION: Hypercalcemia can be masked during pregnancy and in severe pancreatitis, as was detected in about half of the case series. Clinicians should have a high level of suspicion of parathyroid adenoma in cases with a profound pancreatitis. Timely diagnosis and early therapeutic intervention are important to resolve complications and improve the outcomes of mothers and fetuses.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review

  3 / 5656 MEDLINE  
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[PMID]: 24183089
[Au] Autor:Doizi S; Letendre J; Bensalah K; Traxer O
[Ad] Address:Service d'urologie, université Pierre et Marie Curie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France. Electronic address: steeve.doizi@gmail.com.
[Ti] Title:Prise en charge pharmacologique de la lithiase urinaire. [Pharmacologic treatment of urinary stones].
[So] Source:Prog Urol;23(15):1312-7, 2013 Nov.
[Is] ISSN:1166-7087
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:AIM: To describe the pharmacotherapy of urinary lithiasis. METHOD: Results of a literature search (PubMed) was summarized by an experts board. RESULTS: The incidence of urolithiasis constantly increases in industrialized countries and its prevalence in France is estimated around 10% in the general population. Due to its high recurrence rate urolithiasis is a public health concern. Significant progresses in both surgery and pharmacotherapy during the last thirty years markedly improve prognostic of high recurrence risk patients. CONCLUSION: Better understanding of the physiologic disturbances involve in stone formation has allowed to identify at lest one factor in every subset of patient in which diet and pharmacotherapy will reduce the recurrence rate. In this review are discussed treatments of the crisis as well as the metabolic treatment.
[Mh] MeSH terms primary: Urinary Calculi/drug therapy
[Mh] MeSH terms secundary: Anti-Bacterial Agents/therapeutic use
Chelating Agents/therapeutic use
Citric Acid/therapeutic use
Humans
Hydrogen-Ion Concentration
Methionine/therapeutic use
Sodium Chloride Symporter Inhibitors/therapeutic use
Urinary Calculi/etiology
Urinary Tract Infections/complications
Urine/chemistry
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Nm] Name of substance:0 (Anti-Bacterial Agents); 0 (Chelating Agents); 0 (Sodium Chloride Symporter Inhibitors); 2968PHW8QP (Citric Acid); AE28F7PNPL (Methionine)
[Em] Entry month:1407
[Js] Journal subset:IM
[Da] Date of entry for processing:131104
[St] Status:MEDLINE

  4 / 5656 MEDLINE  
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[PMID]: 24086562
[Au] Autor:Sharma A; Prasongwattana V; Cha'on U; Selmi C; Hipkaeo W; Boonnate P; Pethlert S; Titipungul T; Intarawichian P; Waraasawapati S; Puapiroj A; Sitprija V; Reungjui S
[Ad] Address:Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
[Ti] Title:Monosodium glutamate (MSG) consumption is associated with urolithiasis and urinary tract obstruction in rats.
[So] Source:PLoS One;8(9):e75546, 2013.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: The peritoneal injection of monosodium glutamate (MSG) can induce kidney injury in adult rats but the effects of long-term oral intake have not been determined. METHODS: We investigated the kidney histology and function in adult male Wistar rats that were fed ad libitum with a standard rat chow pellet and water with or without the addition of 2 mg/g body weight MSG/day in drinking water (n=10 per group). Both MSG-treated and control animals were sacrificed after 9 months when renal function parameters, blood and urine electrolytes, and tissue histopathology were determined. RESULTS: MSG-treated rats were more prone to kidney stone formation, as represented by the alkaline urine and significantly higher activity product of calcium phosphate. Accordingly, 3/10 MSG-treated rats developed kidney stones over 9 months versus none of the control animals. Further, 2/10 MSG-treated rats but none (0/10) of the controls manifested hydronephrosis. MSG-treated rats had significantly higher levels of serum creatinine and potassium including urine output volume, urinary excretion sodium and citrate compared to controls. In contrast, MSG-treated rats had significantly lower ammonium and magnesium urinary excretion. CONCLUSION: Oral MSG consumption appears to cause alkaline urine and may increase the risks of kidney stones with hydronephrosis in rats. Similar effects in humans must be verified by dedicated studies.
[Mh] MeSH terms primary: Sodium Glutamate/adverse effects
Urolithiasis/etiology
Urologic Diseases/etiology
[Mh] MeSH terms secundary: Animals
Eating/physiology
Electrolytes/blood
Electrolytes/urine
Kidney/pathology
Kidney Calculi/blood
Kidney Calculi/etiology
Kidney Calculi/pathology
Kidney Calculi/urine
Kidney Function Tests/methods
Male
Rats
Rats, Wistar
Sodium/metabolism
Urolithiasis/blood
Urolithiasis/pathology
Urolithiasis/urine
Urologic Diseases/blood
Urologic Diseases/pathology
Urologic Diseases/urine
Water/metabolism
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Electrolytes); 059QF0KO0R (Water); 9NEZ333N27 (Sodium); W81N5U6R6U (Sodium Glutamate)
[Em] Entry month:1407
[Js] Journal subset:IM
[Da] Date of entry for processing:131002
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0075546

  5 / 5656 MEDLINE  
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[PMID]: 24034803
[Au] Autor:Luque Paz D; Meskar A; Kerspern H; Bordron A; Carré JL
[Ad] Address:Département de biochimie et pharmaco-toxicologie, hôpital de la Cavale-Blanche, CHRU de Brest, 29609 Brest cedex, France.
[Ti] Title:Proposition de "profils types" des calculs urinaires dans une population pédiatrique bretonne. [Classification of urinary calculi in a pediatric population from Brittany].
[So] Source:Prog Urol;23(10):899-905, 2013 Sep.
[Is] ISSN:1166-7087
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:INTRODUCTION: Urinary lithiasis in children is relatively seldom in France as in industrialized countries. The determination of their etiology based on their composition may lead to a better treatment. METHOD: One hundred and eight urinary calculi from 6 months through 18-year-old children were analyzed by using spectrophotometry, in order to specify their structure. Six groups were evidenced through a multidimensional analysis based on the presence of components weighing at least 5% of the total. RESULTS: The youngest children affected were mostly boys, and the sex ratio switched after 12.5 years. Above 14 years of age, the number of calculi significantly raised. Their composition varied with the gender, and their localization with the age. Finally a correlation between infection and composition of the calculus was shown in our study. CONCLUSION: The classification of calculi among six groups according to their composition, along with clinical informations and morphologic studies, has proven its value in determining the etiology of the lithiasis. These data help to better understand the kind of lithiasis that may be observed and the physiopathology of the mechanism explaining it from the gender and age.
[Mh] MeSH terms primary: Urinary Calculi/classification
[Mh] MeSH terms secundary: Adolescent
Age Distribution
Calcium Oxalate/analysis
Child
Child, Preschool
Female
France
Humans
Infant
Kidney Pelvis/abnormalities
Male
Phosphates/analysis
Retrospective Studies
Sex Distribution
Spectrophotometry
Ureter/abnormalities
Urinary Calculi/chemistry
Urinary Calculi/epidemiology
Urinary Tract Infections
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Name of substance:0 (Phosphates); 2612HC57YE (Calcium Oxalate)
[Em] Entry month:1407
[Js] Journal subset:IM
[Da] Date of entry for processing:130916
[St] Status:MEDLINE

  6 / 5656 MEDLINE  
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[PMID]: 24892394
[Au] Autor:Palmero JL; Miralles J; Garau C; Nuño de la Rosa I; Amoros A; Benedicto A
[Ad] Address:Unidad de Litotricia y Endourologia. Servicio de Urologia.Hospital Universitario La Ribera.Alzira. Valencia.Spain.
[Ti] Title:Retrograde intrarenal surgery (RIRS) in the treatment of calyceal diverticulum with lithiasis.
[So] Source:Arch Esp Urol;67(4):331-6, 2014 May.
[Is] ISSN:1576-8260
[Cp] Country of publication:Spain
[La] Language:eng; spa
[Ab] Abstract:OBJECTIVES: To evaluate the result of retrograde intrarenal surgery (RIRS) assisted by flexible ureterorenoscopy (FURS) and Holmium laser in the treatment of lithiasis within calyceal diverticula as a minimally invasive therapeutic option. METHODS: We retrospectively evaluated 11 cases of symptomatic lithiasis within calyceal diverticula treated between January 2010 and December 2011. We defined treatment success as absence of residual stones and absence/disappearance of symptomatology over the course of follow-up. We describe the RIRS technique and maneuvers for locating the diverticulum, opening the neck, and fragmenting intradiverticular lithiasis. RESULTS: The most frequently experienced symptom was flank pain (72.7%). The size of the lithiasis treated ranged from 7-20 mm. The overall success rate of RIRS was approximately 73% (absence of lithiasis and disappearance of symptoms) with an average follow-up of 13.3 months. Three cases were not solved by RIRS (2 due to unsuccessful location of the neck, 1 due to persistence of lithiasis and symptoms) . Cases of unsuccessful location were treated with laparoscopic surgery. CONCLUSION: RIRS assisted by FURS and Holmium laser is an effective and minimally invasive procedure for the treatment of lithiasis in the interior of the calyceal diverticulum. This treatment's efficacy improves upon the results from ESWL (extracorporeal shock wave lithotripsy( and equals that of the percutaneous method, exhibiting a lower rate of complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1406
[Js] Journal subset:IM
[St] Status:In-Process

  7 / 5656 MEDLINE  
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[PMID]: 24831938
[Au] Autor:Aldosari B; Chossegros C; Stroumsa R
[Ad] Address:Oral and Maxillofacial Department, La Timone University Medical Center, Marseilles, France. Electronic address: dr_badif@hotmail.com.
[Ti] Title:Wharton's duct retropapillary approach.
[So] Source:J Oral Maxillofac Surg;72(6):1124.e1-2, 2014 Jun.
[Is] ISSN:1531-5053
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Salivary lithiasis is more frequently encountered in patients with Wharton's duct. They are often treated with a minimally invasive technique, such as sialendoscopy. The problem with sialendoscopy, in some cases, has been that it will not be possible to cannulate the papilla and, thus, sialendoscopy will not be feasible. Therefore, we have developed and detailed a retropapillary approach to cannulate Wharton's duct in such cases.
[Mh] MeSH terms primary: Endoscopy/methods
Salivary Duct Calculi/surgery
Salivary Ducts/surgery
[Mh] MeSH terms secundary: Catheterization/instrumentation
Dissection/methods
Endoscopes
Humans
Surgical Procedures, Minimally Invasive/instrumentation
Surgical Procedures, Minimally Invasive/methods
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:AIM; D; IM
[Da] Date of entry for processing:140516
[St] Status:MEDLINE

  8 / 5656 MEDLINE  
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[PMID]: 24999474
[Au] Autor:Ito K; Igarashi Y; Okano N; Mimura T; Kishimoto Y; Hara S; Takuma K
[Ad] Address:Division of Gastroenterology and Hepatology, Toho University, Omori Medical Center, 6-11-1 Omori-nishi, Ota-ku, Tokyo 143-8541, Japan....
[Ti] Title:Efficacy of Combined Endoscopic Lithotomy and Extracorporeal Shock Wave Lithotripsy, and Additional Electrohydraulic Lithotripsy Using the SpyGlass Direct Visualization System or X-Ray Guided EHL as Needed, for Pancreatic Lithiasis.
[So] Source:Biomed Res Int;2014:732781, 2014.
[Is] ISSN:2314-6141
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Introduction. To evaluate the efficacy of combined endoscopic lithotomy and extracorporeal shock wave lithotripsy (ESWL), and additional electrohydraulic lithotripsy (EHL) as needed, for the treatment of pancreatic duct stones, we retrospectively evaluated 98 patients with chronic pancreatitis and pancreatic lithiasis. Methods. For the management of main pancreatic duct (MPD) stones in 98 patients, we performed combined endoscopic treatment (ET)/ESWL therapy as the first treatment option. When combined ET/ESWL was unsuccessful, EHL with the SpyGlass Direct Visualization system or X-ray guided EHL was performed. Outpatient ESWL was reserved as one of the final treatment options. Results. Fragmentation was successful in 80 (81.6%) patients as follows: combined ET/ESWL: 67 cases; SpyGlass EHL: 4 cases; X-ray guided EHL: 3 cases; and outpatient ESWL: 6 cases. Successful outcome was obtained by combined ET/ESWL in 67 of the 98 patients (74.5%), by EHL in 7 of 14 patients (7.1%), and by outpatient ESWL in 6 of 6 patients (6.1%). Negotiating the guidewire through a severe MPD stricture was significantly associated with a higher rate of stone fragmentation (P = 0.0003). Conclusions. In cases where combined ET/ESWL was not successful for stone clearance, EHL using the SpyGlass system or X-ray guided EHL was effective in cases where the guidewire could be negotiated through the MPD stricture and it increased the fragmentation rate.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1155/2014/732781

  9 / 5656 MEDLINE  
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[PMID]: 24341294
[Au] Autor:Patel N; Chew B; Knudsen B; Lipkin M; Wenzler D; Sur RL
[Ad] Address:1 Department of Urology, UC San Diego Health System , San Diego, California.
[Ti] Title:Accuracy of endoscopic intraoperative assessment of urologic stone size.
[So] Source:J Endourol;28(5):582-6, 2014 May.
[Is] ISSN:1557-900X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Endoscopic treatment of renal calculi relies on surgeon assessment of residual stone fragment size for either basket removal or for the passage of fragments postoperatively. We therefore sought to determine the accuracy of endoscopic assessment of renal calculi size. MATERIALS AND METHODS: Between January and May 2013, five board-certified endourologists participated in an ex vivo artificial endoscopic simulation. A total of 10 stones (pebbles) were measured (mm) by nonparticipating urologist (N.D.P.) with electronic calibers and placed into separate labeled opaque test tubes to prevent visualization of the stones through the side of the tube. Endourologists were blinded to the actual size of the stones. A flexible digital ureteroscope with a 200-µm core sized laser fiber in the working channel as a size reference was placed through the ureteroscope into the test tube to estimate the stone size (mm). Accuracy was determined by obtaining the correlation coefficient (r) and constructing an Altman-Bland plot. RESULTS: Endourologists tended to overestimate actual stone size by a margin of 0.05 mm. The Pearson correlation coefficient was r=0.924, with a p-value<0.01. The estimation of small stones (<4 mm) had a greater accuracy than large stones (≥4 mm), r=0.911 vs r=0.666. Altman-bland plot analysis suggests that surgeons are able to accurately estimate stone size within a range of -1.8 to +1.9 mm. CONCLUSIONS: This ex vivo simulation study demonstrates that endoscopic assessment is reliable when assessing stone size. On average, there was a slight tendency to overestimate stone size by 0.05 mm. Most endourologists could visually estimate stone size within 2 mm of the actual size. These findings could be generalized to state that endourologists are accurately able to intraoperatively assess residual stone fragment size to guide decision making.
[Mh] MeSH terms primary: Ureteroscopes
Urolithiasis/pathology
Urology
[Mh] MeSH terms secundary: Adult
Female
Humans
Intraoperative Period
Male
Middle Aged
Reference Values
Ureteroscopy
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Js] Journal subset:IM
[Da] Date of entry for processing:140421
[St] Status:MEDLINE
[do] DOI:10.1089/end.2013.0707

  10 / 5656 MEDLINE  
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[PMID]: 24100641
[Au] Autor:Strohmaier WL; Hörmann M; Schubert G
[Ad] Address:Department of Urology and Paediatric Urology, RegioMed Kliniken, Klinikum Coburg, Ketschendorfer Str. 33, 96450, Coburg, Germany, walter.strohmaier@klinikum-coburg.de.
[Ti] Title:Papillary calcifications: a new prognostic factor in idiopathic calcium oxalate urolithiasis.
[So] Source:Urolithiasis;41(6):475-9, 2013 Nov.
[Is] ISSN:2194-7236
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Metabolic evaluation is not suitable to forecast the course of the disease in idiopathic calcium oxalate stone formation (iCaOxU). An important pathway in CaOx stone formation is the overgrowth on interstitial apatite papillary plaques. Therefore, we studied whether the extent of such plaques may be used as a prognostic factor in CaOxU. Prospectively, we studied n = 100 patients with iCaOxU. For stone analysis, X-ray diffraction/polarizing microscopy was used. During flexible ureteroscopy and flexible percutaneous nephrolithotomy, all the renal papillae were inspected, counted and the severity of calcifications assessed. A calcification index (CI) was calculated: sum of the No. of papillae × calcification grade (1-3) × No. of calcified/total No. of papillae. Furthermore, the following parameters were examined in all patients: age, sex, BMI, arterial blood pressure, stone episodes, DM; blood: creatinine, glucose, uric acid, calcium, sodium and potassium; urine: pH, volume, calcium, uric acid, citrate, ammonia and urea. Using the statistic programme Prism 5 (GraphPad), summary statistics and non-parametric correlations (Spearman) and their significance were calculated. The CI correlated significantly (r = 0.37; p = 0.012) with the No. of stone episodes. Apart from citrate (r = 0.51; p = 0.002), none of the conventional metabolic parameters correlated significantly with the No. of stone episodes. Paradoxically, the citrate excretion-although citrate being an inhibitor of CaOx stone formation-positively correlated to the recurrence rate. The endoscopic assessment of papillary plaques/calcifications and the calculation of the CI are a more suitable prognostic factor in CaOx than conventional metabolic evaluation.
[Mh] MeSH terms primary: Calcinosis/metabolism
Calcium Oxalate/metabolism
Kidney Medulla/metabolism
Urolithiasis/etiology
[Mh] MeSH terms secundary: Adult
Aged
Humans
Middle Aged
Prognosis
Prospective Studies
Ureteroscopy
Urolithiasis/diagnosis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:2612HC57YE (Calcium Oxalate)
[Em] Entry month:1407
[Js] Journal subset:IM
[Da] Date of entry for processing:131113
[St] Status:MEDLINE
[do] DOI:10.1007/s00240-013-0606-3


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