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[PMID]: 25060549
[Au] Autor:Medina-Escobedo M; González-Herrera L; Villanueva-Jorge S; Martín-Soberanis G
[Ad] Address:Research Unit on Kidney Diseases, General Hospital "Dr. Agustin O'Horan", Health Services of Yucatan, Av. Itzáes por Jacinto Canek s/n, Col. Centro, 97000, Mérida, Yucatán, Mexico, marthamedinaescobedo@hotmail.com.
[Ti] Title:Metabolic abnormalities and polymorphisms of the vitamin D receptor (VDR) and ZNF365 genes in children with urolithiasis.
[So] Source:Urolithiasis;42(5):395-400, 2014 Oct.
[Is] ISSN:2194-7236
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Composition of urinary stones in children from Yucatán, México, is calcium and uric acid. Polymorphisms in VDR and ZNF365 genes have been associated to calcium and uric acid lithiasis, respectively. We evaluated the association of polymorphisms TaqI and FokI of VDR gene and Ala62Thr of ZNF365 gene with the metabolic disorders (MD) in children with urolithiasis (UL). We included 109 children with UL. Creatinine, calcium, phosphorus, magnesium, uric acid, oxalates and citrates were measured in fresh urine. Urinary indices were calculated for determining the MD. VDR and ZNF365 polymorphisms were determined by PCR-RFLP. Genotype frequencies were compared with the frequency of MD and with the averages of excretion of the analytes, using the statistical package STATA 11.0. The most frequent MD were hypocitraturia (35.8 %) and hyperuricosuria (22.9 %). The comparison of genotype frequencies with the frequency of MD did not show significant differences (p > 0.05). The comparison of the urinary excretion averages of analytes with respect to the genotype showed that GG homozygotes have higher concentrations of uric acid and citrate than AG heterozygotes (p = 0.03), and that fF heterozygotes have lower concentrations of citrate (p = 0.009). Hypocitraturia and hyperuricosuria were the most common metabolic disorders. The frequency of MD is not associated with polymorphisms. However, in children with urolithiasis of Yucatan, GG homozygotes excrete higher concentrations of uric acid and citrates, and fF heterozygotes have lower concentrations of citrates.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00240-014-0683-y

  2 / 5705 MEDLINE  
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[PMID]: 24465157
[Au] Autor:Namgoong JM; Kim KH; Park GC; Jung DH; Song GW; Ha TY; Moon DB; Ahn CS; Hwang S; Lee SG
[Ad] Address:Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea....
[Ti] Title:Comparison of laparoscopic versus open left hemihepatectomy for left-sided hepatolithiasis.
[So] Source:Int J Med Sci;11(2):127-33, 2014.
[Is] ISSN:1449-1907
[Cp] Country of publication:Australia
[La] Language:eng
[Ab] Abstract:PURPOSE: The purpose of this study was to evaluate and compare the perioperative and long-term outcomes of open versus laparoscopic left hemihepatectomy (OLH vs. LLH) for left-sided hepatolithiasis. METHODS: Between October 2007 and June 2012, 149 patients with left-sided hepatolithiasis who underwent LLH (n = 37) or OLH (n = 112) were evaluated. The perioperative and long-term outcomes that were reviewed included the stone clearance rate, operative morbidity and mortality, and the stone recurrence rate. RESULTS: The mean operative time of the LLH group was significantly longer than that of the OLH group (257±50.4 minutes vs. 237±75.5 minutes, p = 0.022), but the mean hospital stay was significantly shorter (8.8±4.10 vs. 14.1±4.98 days, p < 0.001). Postoperative complications were noted in four and twenty cases among LLH and OLH patients, respectively (p = 0.982). The initial clearance rate of intrahepatic duct (IHD) stones was 100% and 96.4% in the LLH and OLH groups, respectively, but all remnant stones (n = 4, OLH group) were resolved postoperatively. There were two cases of recurrence of IHD stones in OLH patients, but none in LLH patients (p = 0.281). CONCLUSIONS: In left-sided hepatolithiasis, LLH was safe and effective: it resulted in low postoperative morbidity, no mortality and a high stone clearance rate, and there were no incidences of recurrence in our study. The potential benefits of LLH include a shorter hospital stay and a faster return to oral intake. If consideration is given to the appropriate indication criteria, including the extent of hepatectomy and the location and distribution of lesions, LLH may be an excellent choice for treatment of left-sided hepatolithiasis.
[Mh] MeSH terms primary: Hepatectomy
Laparoscopy
Lithiasis/surgery
Liver Diseases/surgery
Liver/surgery
[Mh] MeSH terms secundary: Adult
Bile Ducts, Intrahepatic
Female
Humans
Lithiasis/pathology
Liver/pathology
Liver Diseases/pathology
Male
Middle Aged
Postoperative Complications
Treatment Outcome
[Pt] Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[Da] Date of entry for processing:140127
[St] Status:MEDLINE
[do] DOI:10.7150/ijms.7516

  3 / 5705 MEDLINE  
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[PMID]: 25149621
[Au] Autor:Simion L; Straja D; Prunoiu V; Alecu M; Bratucu E; -
[Ti] Title:Choleperitoneum due to intrahepatic bile duct rupture - case report.
[So] Source:Chirurgia (Bucur);109(4):542-5, 2014 Jul-Aug.
[Is] ISSN:1221-9118
[Cp] Country of publication:Romania
[La] Language:eng
[Ab] Abstract:Non-traumatic perforations of the bile ducts are unfrequently encountered entities, all the more when they affect the intrahepatic bile ducts, exteriorizing their biliary content in the great peritoneal cavity. Reporting such a case has determined the authors to perform a careful overview of the cases present in the literature. An observation that can be made based on these is that the obstruction of the main bile duct due to lithiasis determines, by pressure increase, the dilation of the bile system branches, all on the background of an unknown malformation of the intrahepatic bile ducts.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Process

  4 / 5705 MEDLINE  
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[PMID]: 23949189
[Au] Autor:Bircan A; Onur D; Yilmaz A
[Ad] Address:Department of Pulmonary Medicine, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey.
[Ti] Title:Broncholithiasis with recurrent lithoptysis: a case report.
[So] Source:Med Princ Pract;23(1):83-5, 2014.
[Is] ISSN:1423-0151
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To report a case of broncholithiasis with different types of calculi in the tracheobronchial tree. CLINICAL PRESENTATION AND INTERVENTION: A 50-year-old male who suffered from hemoptysis presented with recurrent broncholith expectoration due to past tuberculous middle lobe syndrome. Bronchoscopic examination revealed loose and embedded broncholiths located at two different bronchi. A surgical resection was suggested, but he refused. CONCLUSION: The diagnosis of broncholithiasis should be kept in mind in patients who had hemoptysis and calcified mediastinal lymph nodes on thorax computerized tomography, and diagnostic bronchoscopy should be done to prove the relationship of the tracheobronchial tree with a broncholith.
[Mh] MeSH terms primary: Bronchial Diseases/complications
Bronchial Diseases/diagnosis
Hemoptysis/etiology
Lithiasis/complications
Lithiasis/diagnosis
[Mh] MeSH terms secundary: Bronchial Diseases/radiography
Humans
Lithiasis/radiography
Male
Middle Aged
Sputum
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[Da] Date of entry for processing:131220
[St] Status:MEDLINE
[do] DOI:10.1159/000351816

  5 / 5705 MEDLINE  
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[PMID]: 24954866
[Au] Autor:Barbier L; Souche R; Slim K; Ah-Soune P
[Ad] Address:Chirurgie Digestive et Transplantation Hépatique, Hôpital La Conception, Assistance publique-Hôpitaux de Marseille, Aix-Marseille Université, 147, boulevard Baille, 13385 Marseille cedex 5, France. Electronic address: louisebarbier@hotmail.fr....
[Ti] Title:Long-term consequences of bile duct injury after cholecystectomy.
[So] Source:J Visc Surg;151(4):269-79, 2014 Sep.
[Is] ISSN:1878-7886
[Cp] Country of publication:France
[La] Language:eng
[Ab] Abstract:Late complications arising after bile duct injury (BDI) include biliary strictures, hepatic atrophy, cholangitis and intra-hepatic lithiasis. Later, fibrosis or even secondary biliary cirrhosis and portal hypertension can develop, enhanced by prolonged biliary obstruction associated with recurrent cholangitis. Secondary biliary cirrhosis resulting in associated hepatic failure or digestive tract bleeding due to portal hypertension is a substantial risk factor for morbidity and mortality after bile duct repair. Parameters that determine the management of late complications of BDI include the type of biliary injury, associated vascular injury, hepatic atrophy, the presence of intra-hepatic strictures or lithiasis, repetitive infectious complications, the quality of underlying parenchyma (fibrosis, secondary biliary cirrhosis) and the presence of portal hypertension. Endoscopic drainage is indicated for patients with uncontrolled acute sepsis, patients at high operative risk, patients with cirrhosis who are not eligible for liver transplantation and patients who have previously undergone several attempts at repair. Roux-en-Y hepaticojejunostomy, whether de novo or as an iterative repair, is the technique of reference for post-cholecystectomy BDI. Hepatic resection is indicated in only rare instances, mainly in case of extended hilar stricture, multiple stone retention in one sector of the liver or in patients for whom the repair is deemed technically difficult. Liver transplantation is indicated only in exceptional circumstances, when secondary biliary cirrhosis is associated with liver failure and portal hypertension.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review

  6 / 5705 MEDLINE  
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[PMID]: 24406866
[Au] Autor:Liau JY; Tsai JH; Yuan RH; Chang CN; Lee HJ; Jeng YM
[Ad] Address:1] Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan [2] Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan....
[Ti] Title:Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features.
[So] Source:Mod Pathol;27(8):1163-73, 2014 Aug.
[Is] ISSN:1530-0285
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:On the basis of morphological features, we subclassified 189 intrahepatic cholangiocarcinomas into two subtypes: bile duct and cholangiolar. The cholangiolar type is composed of cuboidal to low columnar tumor cells that contain scanty cytoplasm. The bile duct type is composed of tall columnar tumor cells arranged in a large glandular pattern. In this study, 77 (41%) tumors were classified as the cholangiolar type and 112 (59%) tumors were classified as the bile duct type. The cholangiolar-type intrahepatic cholangiocarcinoma was more frequently associated with viral hepatitis, whereas all but one intrahepatic cholangiocarcinoma associated with intrahepatic lithiasis were classified as the bile duct type. Biliary intraepithelial neoplasm or intraductal papillary neoplasm of the bile duct could be identified in 50 bile duct-type intrahepatic cholangiocarcinomas (45%), but in only 3 cholangiolar-type intrahepatic cholangiocarcinomas (4%). Cholangiolar-type intrahepatic cholangiocarcinomas frequently expressed N-cadherin, whereas bile duct intrahepatic cholangiocarcinomas were more likely to express S100P, Trefoil factor 1, and anterior gradient 2. KRAS is mutated in 23 of 98 (23%) bile duct-type intrahepatic cholangiocarcinomas and in only 1 of 76 (1%) cholangiolar-type intrahepatic cholangiocarcinomas. Cholangiolar-type intrahepatic cholangiocarcinomas had a higher frequency of IDH1 or 2 mutations than did the bile duct-type intrahepatic cholangiocarcinomas. The molecular features of the bile duct-type intrahepatic cholangiocarcinoma were similar to those of hilar cholangiocarcinoma. Patients with the cholangiolar-type intrahepatic cholangiocarcinoma had higher 5-year survival rates than those of patients with the bile duct-type intrahepatic cholangiocarcinoma. Our results indicated that intrahepatic cholangiocarcinoma was a heterogeneous tumor. Subclassification of intrahepatic cholangiocarcinomas based on cholangiocytic differentiation divides them into two groups with different etiologies, clinical manifestations, and molecular pathogeneses.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1408
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1038/modpathol.2013.241

  7 / 5705 MEDLINE  
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[PMID]: 25039525
[Au] Autor:Bond MC; Ellis DH; Sims CC; Wilson LA
[Ad] Address:Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
[Ti] Title:Urolithiasis as an unusual cause of failure to thrive.
[So] Source:J Am Geriatr Soc;62(7):1409-10, 2014 Jul.
[Is] ISSN:1532-5415
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Failure to Thrive/etiology
Urolithiasis/complications
[Mh] MeSH terms secundary: Aged
Female
Humans
[Pt] Publication type:CASE REPORTS; LETTER
[Em] Entry month:1409
[Js] Journal subset:IM
[Da] Date of entry for processing:140721
[St] Status:MEDLINE
[do] DOI:10.1111/jgs.12908

  8 / 5705 MEDLINE  
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[PMID]: 25214292
[Au] Autor:Laclergerie F; Jacquemet B; Guichard G; Bernardini S; Chabannes E; Martin L; Pastori J; Bailly V; Bittard H; Kleinclauss F
[Ad] Address:Département d'urologie et de transplantation rénale, CHU Jean-Minjoz, université de Franche-Comté, 25030 Besançon, France....
[Ti] Title:Urétérorénoscopie souple avec laser Holmium-YAG dans la prise en charge des lithiases urinaires chez le patient obèse : résultats d'une cohorte monocentrique. [Flexible ureterorenoscopy in obese patients: Results from a large monocenter cohort].
[So] Source:Prog Urol;24(10):634-9, 2014 Sep.
[Is] ISSN:1166-7087
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:OBJECTIVE: To analyze results and morbidity after flexible ureterorenoscopy (fURS) in patients with a body mass index (BMI)>30kg/m(2) and to compare with results obtained in a large cohort of non-obese patients. METHODS: We conducted a retrospective monocenter study including all fURS for urinary lithiasis performed in our institution between January 2004 and December 2010. During the study period, 497 procedures were performed. Twenty-three had to be excluded because of missing data on BMI. Thus, a total of 474 procedures were included in the final analysis, 93 for obese patients (OP) and 381 for non-obese patients (NOP). Characteristics of the patients, stones and procedures were analyzed. Success was defined as clear imaging (completely stone-free) on renal tomography and ultrasonography. RESULTS: Mean BMI was 33.5±0.3 in OP vs 23.9±0.1kg/m(2) in NOP (P<0.0001). Mean stone size, location, and composition were not significantly different between groups. Technical aspects (operative time, ureteral dilatation, access sheath, monobloc extraction) were also similar in OP and NOP. The immediate (63.5% for OP vs 66.1% in NOP, P=0.62) and follow-up (65.1% for OP vs 71% in NOP, P=0.26) stone-free rate were not significantly different between the groups. For stone size<1cm, SFR raised to 77% in OP vs 83% in NOP (P=0.28). The rate of minor complications Clavien II was similar in OP (7.5%) and NOP (12%). No major complication (Clavien III or IV) was observed. CONCLUSION: fURS is a safe and efficient option for the management of urinary lithiasis in obese patients.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Data-Review

  9 / 5705 MEDLINE  
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[PMID]: 25199305
[Au] Autor:Dietrich A; Ardiles V; Lendoire J; Raffin G; Moro M; Storck G; Russi R; Barros Schelotto P; de Santibañes E; Pekolj J
[Ti] Title:Hepatectomía en patología hepática no tumoral. experiencia multicéntrica en Argentina. [Liver resection for non tumoral liver disease. Multicentric experience in Argentina].
[So] Source:Acta Gastroenterol Latinoam;44(2):114-20, 2014 Jun.
[Is] ISSN:0300-9033
[Cp] Country of publication:Argentina
[La] Language:spa
[Ab] Abstract:BACKGROUND: The role of liver resection (LR) in patients with non-tumoral hepatic disease (NTHD) remains controversial. OBJECTIVE: To analyze the indications and outcomes of liver resections in patients with NTHD. METHODS: A retrospective analysis in a multicentric data base was performed. Outcome measures were incidence of postoperative cholangitis, infectious and non-infectious complications, hospital stay and overall mortality. RESULTS: One hundred and fourteen patients underwent LR due to NTHD from January 2001 to November 2011. Fourteen patients presented complex bile duct injuries (CBDI), 18 intra-hepatic lithiasis (IL), 32 liver hydatid cysts (LHC), 10 polycystic liver disease (PLD), 19 Caroli's disease (CD) and 21 other NTHD. Forty seven patients underwent a major hepatectomy and 67 a liver segmentectomy or an atypical liver resection. Thirty four patients (29%) presented surgical related complications. There was not intra or post-operative mortality. In long term outcomes, 98 patients (85%) were asymptomatic, 10 presented episodes of intermittent cholangitis that were treated with antibiotics, and 7 underwent another surgical procedure. CONCLUSIONS: LR is a radical and effective procedure to treat benign NTHD instead of other surgical or percutaneous procedures, avoiding multiple sessions of treatment and high post procedure complications rates.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[St] Status:In-Process

  10 / 5705 MEDLINE  
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[PMID]: 25055538
[Au] Autor:Korolev MP; Fedotov LE; Avanesian RG; Fedotov BL; Khuseinov GA
[Ti] Title:[Modern methods of low-invasive treatment of the stricture and damage of the pancreatic duct, pancreatolithiasis].
[So] Source:Vestn Khir Im I I Grek;173(2):66-71, 2014.
[Is] ISSN:0042-4625
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The authors analyzed the experience of diagnostics and treatment of 49 patients. It was shown, that low-invasive methods of treatment (the endoscopic lithoextraction, stenting, surgical drainage) should be the priority means in treatment of pancreatolithiasis, strictures and cases of the pancreatic duct damage. The lethality consisted of 2.04% in these interventions.
[Mh] MeSH terms primary: Endoscopy, Digestive System
Lithiasis
Pancreatic Ducts
Pancreatitis, Chronic
Postoperative Complications
[Mh] MeSH terms secundary: Adult
Cholangiopancreatography, Endoscopic Retrograde/methods
Constriction, Pathologic/radiography
Constriction, Pathologic/surgery
Decompression, Surgical/methods
Endoscopy, Digestive System/instrumentation
Endoscopy, Digestive System/methods
Female
Humans
Lithiasis/complications
Lithiasis/surgery
Male
Pancreatic Ducts/pathology
Pancreatic Ducts/physiopathology
Pancreatic Ducts/surgery
Pancreatitis, Chronic/diagnosis
Pancreatitis, Chronic/etiology
Pancreatitis, Chronic/physiopathology
Pancreatitis, Chronic/surgery
Postoperative Complications/etiology
Postoperative Complications/prevention & control
Stents
Surgical Procedures, Minimally Invasive/methods
Treatment Outcome
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1409
[Js] Journal subset:IM
[Da] Date of entry for processing:140724
[St] Status:MEDLINE


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