Database : MEDLINE Search on : Monimiaceae [Words] References found : 23 [refine] Displaying: 1 .. 10   in format [Detailed]

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[PMID]: 22626446 [Au] Autor: Carr G; Williams DE; Ratnayake R; Bandara R; Wijesundara S; Tarling T; Balgi AD; Roberge M; Andersen RJ; Karunaratne V [Ad] Address: Department of Chemistry and Earth, University of British Columbia, Vancouver, British Columbia, Canada. [Ti] Title: Hortonones A to C, hydroazulenones from the genus Hortonia. [So] Source: J Nat Prod;75(6):1189-91, 2012 Jun 22. [Is] ISSN: 1520-6025 [Cp] Country of publication: United States [La] Language: eng [Ab] Abstract: The new hexahydroazulenones hortonones A (1) to C (3) were isolated from the leaves of three representative species of the endemic Sri Lankan genus Hortonia that belongs to the family Monimiaceae. Hortonones A (1) and B (2) have the unprecedented rearranged hortonane sesquiterpenoid carbon skeleton, and hortonone C (3) has the unprecedented rearranged and degraded 13-norhortonane skeleton. Hortonone C (3) exhibited in vitro cytotoxicity against human breast cancer MCF-7 cells at 5 µg/mL. [Mh] MeSH terms primary: Antineoplastic Agents, Phytogenic/isolation & purification Diterpenes/isolation & purification Monimiaceae/chemistry [Mh] MeSH terms secundary: Antineoplastic Agents, Phytogenic/chemistry Antineoplastic Agents, Phytogenic/pharmacology Breast Neoplasms Diterpenes/chemistry Diterpenes/pharmacology Drug Screening Assays, Antitumor Female Humans Molecular Structure Plant Leaves/chemistry Sri Lanka [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Name of substance: 0 (Antineoplastic Agents, Phytogenic); 0 (Diterpenes); 0 (hortonone A); 0 (hortonone B); 0 (hortonone C) [Em] Entry month: 1209 [Js] Journal subset: IM [Da] Date of entry for processing: 120622 [St] Status: MEDLINE [do] DOI: 10.1021/np200927k

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[PMID]: 21152766 [Au] Autor: Novaes Fda S; Callado CH; Pereira-Moura MV; Lima HR [Ad] Address: Universidade Federal Rural do Rio de Janeiro, Instituto de Biologia, Departamento de Botânica, Caixa Postal 74582, Seropédica, RJ, Brasil. [Ti] Title: Wood anatomy of Mollinedia glabra (Spreng.) Perkins (Monimiaceae) in two Restinga Vegetation Formations at Rio das Ostras, RJ, Brazil. [So] Source: An Acad Bras Cienc;82(4):915-24, 2010 Dec. [Is] ISSN: 1678-2690 [Cp] Country of publication: Brazil [La] Language: eng [Ab] Abstract: This paper aimed to characterize the anatomical structure of the wood of specimens of Mollinedia glabra (Spreng.) Perkins growing in two contiguous formations of restinga vegetation at Praia Virgem, in the municipality of Rio das Ostras, RJ. Both the Open Palmae (OPS) and the Sandy Strip Closed Shrub (SSCS) formations are found in coastal regions that receive between 1,100 and 1,300 mm of rainfall per year. Sapwood samples were collected in both formations. Typical anatomical features for this species include: solitary vessels, radial multiples or clusters elements, that are circular to angular in outline, 5-15 barred scalariform perforation plates, wood parenchyma scanty, septate fiber-tracheids, and wide multiseriate rays with prismatic crystals. Statistical analyses indicated a significant increase in the frequency of vessel elements and an increase in fiber-tracheid diameters in OPS individuals. These characteristics are considered structural adaptations to increased water needs caused by a greater exposure to sunlight. Continuous pruning may be responsible for the tyloses observed in OPS plants. The greater lengths and higher frequencies of the rays in SSCS trees may be due to the greater diameters of their branches. Our results suggest that M. glabra develops structural adaptations to the restinga micro-environmental variations during its development. [Mh] MeSH terms primary: Monimiaceae/anatomy & histology Wood/anatomy & histology [Mh] MeSH terms secundary: Brazil Monimiaceae/classification [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Entry month: 1108 [Js] Journal subset: IM [Da] Date of entry for processing: 101214 [St] Status: MEDLINE

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[PMID]: 20022332 [Au] Autor: Simirgiotis MJ; Schmeda-Hirschmann G [Ad] Address: Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile. [Ti] Title: Direct identification of phenolic constituents in Boldo Folium (Peumus boldus Mol.) infusions by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry. [So] Source: J Chromatogr A;1217(4):443-9, 2010 Jan 22. [Is] ISSN: 1873-3778 [Cp] Country of publication: Netherlands [La] Language: eng [Ab] Abstract: A very simple and direct method was developed for the qualitative analysis of polyphenols in boldo (Peumus boldus Mol., Monimiaceae) leaves infusions by high-performance liquid chromatography with diode array detection (HPLC-DAD) and electrospray ionization tandem mass spectrometry (HPLC-MS(n)). The phenolic constituents identified in infusions of the crude drug Boldo Folium were mainly proanthocyanidins and flavonol glycosides. In the infusions, 41 compounds were detected in male and 43 compounds in female leaf samples, respectively. Nine quercetin glycosides, eight kaempferol derivatives, nine isorhamnetin glycosides, three phenolic acids, one caffeoylquinic acid glycoside and twenty one proanthocyanidins were identified by HPLC-DAD and ESI-MS for the first time in the crude drug. Isorhamnetin glucosyl-di-rhamnoside was the most abundant flavonol glycoside in the male boldo sample, whereas isorhamnetin di-glucosyl-di-rhamnoside was the main phenolic compound in female boldo leaves infusion. The results suggest that the medicinal properties reported for this popular infusion should be attributed not only to the presence of catechin and boldine but also to several phenolic compounds with known antioxidant activity. The HPLC fingerprint obtained can be useful in the authentication of the crude drug Boldo Folium as well as for qualitative analysis and differentiation of plant populations in the tree distribution range. [Mh] MeSH terms primary: Chromatography, High Pressure Liquid/methods Peumus/chemistry Phenols/analysis Spectrometry, Mass, Electrospray Ionization/methods [Mh] MeSH terms secundary: Chromatography, High Pressure Liquid/economics Molecular Structure Phenols/chemistry Plant Leaves/chemistry Spectrometry, Mass, Electrospray Ionization/economics Tandem Mass Spectrometry/economics Tandem Mass Spectrometry/methods [Pt] Publication type: JOURNAL ARTICLE [Nm] Name of substance: 0 (Phenols) [Em] Entry month: 1004 [Js] Journal subset: IM [Da] Date of entry for processing: 100128 [St] Status: MEDLINE [do] DOI: 10.1016/j.chroma.2009.11.014

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[PMID]: 19145575 [Au] Autor: Fernández J; Lagos P; Rivera P; Zamorano-Ponce E [Ad] Address: Universidad del Bío-Bío, Casilla 447, Chillán, Chile. [Ti] Title: Effect of boldo (Peumus boldus Molina) infusion on lipoperoxidation induced by cisplatin in mice liver. [So] Source: Phytother Res;23(7):1024-7, 2009 Jul. [Is] ISSN: 1099-1573 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: Peumus boldus Molina (Monimiaceae), commonly referred to as 'boldo', is used in traditional Chilean medicine to treat hepatic and gastrointestinal diseases. Its leaves are rich in antioxidant compounds, principally alkaloids and flavonoids. This study evaluates the protective effect of a complete boldo leaf infusion on lipoperoxidation (MDA determination at 532 nm) induced by cisplatin in mice liver. To determine if the observed effect can be explained by the action of boldine or catechin, each compound was studied separately. The mice were divided into 8 groups (n = 6): (I) not treated; (II) treated with cisplatin 6 mg/Kg b.w.; (III) treated with boldo leaf infusion 5%; (IV) pretreated with boldo leaf infusion 5% and treated with cisplatin 6 mg/Kg b.w.; (V) treated with boldine 50 mg/Kg b.w.; (VI) pretreated with boldine 50 mg/Kg b.w. and treated with cisplatin 6 mg/kg.b.w.; (VII) treated with catechin; and (VIII) pretreated with catechin 50 mg/Kg b.w. and treated with cisplatin 6 mg/Kg b.w. As expected, the treatment with cisplatin significantly increased (p < 0.01) lipoperoxidation in comparison with the non-treated group. Pretreatment with boldo leaf infusion significantly diminished (p < 0.05) the lipoperoxidation induced by cisplatin with respect to the animals not pretreated with the infusion. The pretreatments with boldine and catechin significantly diminished (p < 0.05) the lipoperoxidation induced by cisplatin with respect to the group treated only with cisplatin. The results suggest that the boldo infusion is acting as a protector with respect to the oxidative hepatic damage caused by cisplatin, and that this protective ability would be due to the presence in the infusion of the natural antioxidants boldine and principally catechin. These findings suggest the potential use of the infusion as a chemoprotector. [Mh] MeSH terms primary: Cisplatin/pharmacology Lipid Peroxidation/drug effects Liver/drug effects Peumus/chemistry Plant Extracts/pharmacology [Mh] MeSH terms secundary: Animals Aporphines/pharmacology Catechin/pharmacology Liver/metabolism Male Mice Mice, Inbred BALB C Oxidative Stress/drug effects Plant Leaves/chemistry [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Name of substance: 0 (Aporphines); 0 (Plant Extracts); 154-23-4 (Catechin); 15663-27-1 (Cisplatin); 8I91GE2769 (boldine) [Em] Entry month: 0907 [Cu] Class update date: 121115 [Lr] Last revision date: 121115 [Js] Journal subset: IM [Da] Date of entry for processing: 090625 [St] Status: MEDLINE [do] DOI: 10.1002/ptr.2746

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[PMID]: 19514108 [Au] Autor: Valadeau C; Pabon A; Deharo E; Albán-Castillo J; Estevez Y; Lores FA; Rojas R; Gamboa D; Sauvain M; Castillo D; Bourdy G [Ad] Address: IFEA UMIFRE 17 CNRS/MAEE, Casilla 18-1217, Lima, Peru. [Ti] Title: Medicinal plants from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of selected extracts. [So] Source: J Ethnopharmacol;123(3):413-22, 2009 Jun 25. [Is] ISSN: 1872-7573 [Cp] Country of publication: Ireland [La] Language: eng [Ab] Abstract: AIM OF THE STUDY: Ninety-four ethanolic extracts of plants used medicinally by the Yanesha, an Amazonian Peruvian ethnic group, for affections related to leishmaniasis and malaria were screened in vitro against Leishmania amazonensis amastigotes and against a Plasmodium falciparum chloroquine resistant strain. MATERIALS AND METHODS: The viability of Leishmania amazonensis amastigote stages was assessed by the reduction of tetrazolium salt (MTT) while the impact on Plasmodium falciparum was determined by measuring the incorporation of radio-labelled hypoxanthine. RESULTS AND CONCLUSIONS: Six plant species displayed good activity against Plasmodium falciparum chloroquine resistant strain (IC(50) < 10 microg/ml): a Monimiaceae, Siparuna aspera (Ruiz & Pavon), A. DC., two Zingiberaceae, Renealmia thyrsoidea (Ruiz & Pavon) Poepp. & Endl. and Renealmia alpinia (Rottb.), two Piperaceae (Piper aduncum L. and Piper sp.) and the leaves of Jacaranda copaia (Aubl.) D. Don (Bignoniaceae). Eight species displayed interesting leishmanicidal activities (IC50 < 10 microg/ml): Carica papaya L. (Caricaceae), Piper dennisii Trel (Piperaceae), Hedychium coronarium J. König (Zingiberaceae), Cestrum racemosum Ruiz & Pav. (Solanaceae), Renealmia alpinia (Rottb.) Zingiberaceae, Lantana sp. (Verbenaceae), Hyptis lacustris A. St.-Hil. ex Benth. (Lamiaceae) and Calea montana Klat. (Asteraceae). Most of them are used against skin affections by Yanesha people. Results are discussed herein, according to the traditional use of the plants and compared with data obtained from the literature. [Mh] MeSH terms primary: Angiosperms Antimalarials/pharmacology Leishmania/drug effects Plant Extracts/pharmacology Plants, Medicinal Plasmodium falciparum/drug effects Trypanocidal Agents/pharmacology [Mh] MeSH terms secundary: Animals Drug Resistance Life Cycle Stages Medicine, Traditional Parasitic Sensitivity Tests Peru [Pt] Publication type: EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Name of substance: 0 (Antimalarials); 0 (Plant Extracts); 0 (Trypanocidal Agents) [Em] Entry month: 0910 [Js] Journal subset: IM [Da] Date of entry for processing: 090609 [St] Status: MEDLINE

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[PMID]: 19023800 [Au] Autor: Ratnayake R; Ratnayake Bandara BM; Wijesundara S; Macleod JK; Simmonds P; Karunaratne V [Ad] Address: Department of Chemistry, University of Peradeniya, Peradeniya, Sri Lanka. [Ti] Title: Bioactivity and chemistry of the genus Hortonia. [So] Source: Nat Prod Res;22(16):1393-402, 2008. [Is] ISSN: 1478-6427 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: The dichloromethane extracts of the leaves, stem bark, bark and the roots of the three species of the primitive endemic genus Hortonia, H. angustifolia, H. floribunda and H. ovalifolia, collected from nine geographical locations ranging from lower elevations (84-420 m) to higher (2000 m) showed comparable HPLC profiles and mosquito larvicidal and antifungal activities; protein analysis of the leaves of the three species of Hortonia showed identical peaks and bands. The two major metabolites (4S)-4-methyl-2-(11-dodecynyl)-2-butenolide (2) and (4S)-4-methyl-2-(11-dodecenyl)-2-butenolide (3), which were previously reported from all three plants, showed potent larvicidal activities. Compound 2 was excessively high in the extracts of the stem bark and the roots of all three species amounting to approximately 38 and 60%, respectively. A minor new butenolide (4), (4S)-4-methyl-2-((2R)-hydroxy-11-dodecenyl)-2-butenolide, with much reduced larvicidal activity and ishwarane (1), which showed antifungal activity, were also isolated from all three plants. Treatment of compound 2 with H(2)/Pd-C afforded the completely reduced compound 5, which showed no larvicidal activity, indicating that unsaturation in both 2 and 3 is necessary for their bioactivity. The foregoing evidence showed that there are major similarities between the three species of Hortonia. [Mh] MeSH terms primary: 4-Butyrolactone/analogs & derivatives Antifungal Agents/isolation & purification Antifungal Agents/pharmacology Culicidae/drug effects Monimiaceae/chemistry Monimiaceae/metabolism Mosquito Control [Mh] MeSH terms secundary: 4-Butyrolactone/chemistry 4-Butyrolactone/isolation & purification 4-Butyrolactone/pharmacology Animals Antifungal Agents/chemistry Cladosporium/drug effects Larva/drug effects Monimiaceae/genetics Plant Bark/chemistry Plant Leaves/chemistry Plant Roots/chemistry Sri Lanka Structure-Activity Relationship [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S. [Nm] Name of substance: 0 ((4S)-4-methyl-2-(11-dodecenyl)-2-butenolide); 0 ((4S)-4-methyl-2-(11-dodecynyl)-2-butenolide); 0 (Antifungal Agents); 8KXK25H388 (butenolide); 96-48-0 (4-Butyrolactone) [Em] Entry month: 0812 [Cu] Class update date: 121115 [Lr] Last revision date: 121115 [Js] Journal subset: IM [Da] Date of entry for processing: 081121 [St] Status: MEDLINE [do] DOI: 10.1080/14786410701722433

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[PMID]: 17365687 [Au] Autor: Yoder BJ; Cao S; Norris A; Miller JS; Ratovoson F; Andriantsiferana R; Rasamison VE; Kingston DG [Ad] Address: Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. [Ti] Title: Tambouranolide, a new cytotoxic hydroxybutanolide from a Tambourissa sp. (Monimiaceae). [So] Source: Nat Prod Res;21(1):37-41, 2007 Jan. [Is] ISSN: 1478-6419 [Cp] Country of publication: England [La] Language: eng [Ab] Abstract: A new cytotoxic hydroxybutanolide, tambouranolide, has been isolated by solid phase extraction from an ethanol extract of the dried roots of a species of Tambourissa (Monimiaceae) from the Madagascar rainforest. The structure was elucidated through the interpretation of spectral data and its comparison to data reported in the literature for related molecules. The compound showed moderate in vitro cytotoxicity with an IC50 of 8 micro g mL(-1) in the A2780 human ovarian cancer cell line assay. [Mh] MeSH terms primary: Antineoplastic Agents, Phytogenic/isolation & purification Furans/isolation & purification Monimiaceae/chemistry [Mh] MeSH terms secundary: Antineoplastic Agents, Phytogenic/chemistry Antineoplastic Agents, Phytogenic/pharmacology Cell Line, Tumor Furans/chemistry Furans/pharmacology Humans Inhibitory Concentration 50 Molecular Structure Nuclear Magnetic Resonance, Biomolecular Optical Rotation Plant Roots/chemistry Solid Phase Extraction Spectrometry, Mass, Fast Atom Bombardment [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Name of substance: 0 (Antineoplastic Agents, Phytogenic); 0 (Furans) [Em] Entry month: 0705 [Cu] Class update date: 110505 [Lr] Last revision date: 110505 [Js] Journal subset: IM [Da] Date of entry for processing: 070316 [St] Status: MEDLINE

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[PMID]: 16636746 [Au] Autor: Oginuma K; Tobe H [Ad] Address: Department of Environmental Science, Faculty of Human Life and Environmental Science, Kochi Women's University, Kochi, Japan. [Ti] Title: Chromosome evolution in the Laurales based on analyses of original and published data. [So] Source: J Plant Res;119(4):309-20, 2006 Jul. [Is] ISSN: 0918-9440 [Cp] Country of publication: Japan [La] Language: eng [Ab] Abstract: We present a summary of currently available chromosome information for all seven families in the order Laurales on the basis of original and previously published data and discuss the evolution of chromosomes in this order. Based on a total of 53 genera for which chromosome data were available, basic chromosome numbers appear consistent within families: x = 11 (Calycanthaceae); x = 22 (Atherospermataceae and Siparunaceae); x = 19 (Monimiaceae); and x = 12 and 15 (Lauraceae). The Hernandiaceae have diverse numbers: x = 15 (Gyrocarpoideae) and x = 18 and 20 (Hernandioideae). Karyotype analyses showed that Hennecartia, Kibaropsis, and Matthaea (all Monimiaceae) contained two or three sets of four distinct chromosomes in 38 somatic chromosomes, suggesting that 2n = 38 was derived by aneuploid reduction from 2n = 40, a tetraploid of x = 10. In light of the overall framework of phylogenetic relationships in the Laurales, we show that x = 11 is an archaic base number in the order and is retained in the Calycanthaceae, which are sister to the remainder of the order. Polyploidization appears to have occurred from x = 11 to x = 22 in a common clade of the Siparunaceae, Atherospermataceae, and Gomortegaceae (although 2n = 42 in the Gomortegaceae), and aneuploid reduction from x = 11 to x = 10 occurred in a common clade of the Hernandiaceae, Lauraceae, and Monimiaceae. To understand chromosome evolution in the Lauraceae, however, more studies are needed of genera and species of Cryptocaryeae. [Mh] MeSH terms primary: Chromosomes, Plant/genetics Evolution, Molecular Lauraceae/genetics [Mh] MeSH terms secundary: Aneuploidy Karyotyping Polyploidy [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Entry month: 0610 [Cu] Class update date: 061115 [Lr] Last revision date: 061115 [Js] Journal subset: IM [Da] Date of entry for processing: 060724 [St] Status: MEDLINE

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[PMID]: 15085448 [Au] Autor: Heo K; Kimoto Y; Riveros M; Tobe H [Ad] Address: Division of Applied Plant Sciences, Kangwon National University, Chuncheon, Korea. [Ti] Title: Embryology of Gomortegaceae (Laurales): characteristics and character evolution. [So] Source: J Plant Res;117(3):221-8, 2004 Jun. [Is] ISSN: 0918-9440 [Cp] Country of publication: Japan [La] Language: eng [Ab] Abstract: The embryological characteristics of Gomortegaceae, which are poorly understood, were investigated on the basis of Gomortega nitida, the only species of the family, to understand better the evolution of this group within Laurales. Comparisons with other Laurales and Magnoliales (a sister group of Laurales) show that Gomortega has many embryological features in common with the other lauralean families. Notably, Gomortega shares a testa without or with at best only a poorly developed mesotesta as a synapomorphy with all other Laurales. The genus further shares anthers dehisced by valves as a synapomorphy with the other Laurales (except for Calycanthaceae and Monimiaceae), and a non-multiplicative testa and bisporangiate anther as synapomorphies with Atherospermataceae and Siparunaceae (although the non-multiplicative testa occurs as a homoplasy in Monimiaceae, and the bisporangiate anther in Monimiaceae pro parte, Lauraceae pro parte and Hernandiaceae, respectively). Gomortega shows simultaneous cytokinesis to form pollen grains, a one-celled ovule archesporium and non-specialized chalaza, all or part of which may be synapomorphies shared with Atherospermataceae. Gomortega appears to have no embryological autapomorphies, but further comparison with Atherospermataceae is required. [Mh] MeSH terms primary: Angiosperms/embryology Biological Evolution [Mh] MeSH terms secundary: Angiosperms/ultrastructure Fertility Flowers/embryology Flowers/ultrastructure Meristem/embryology Meristem/ultrastructure Microscopy, Electron Seeds/embryology Seeds/ultrastructure [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Entry month: 0410 [Cu] Class update date: 101118 [Lr] Last revision date: 101118 [Js] Journal subset: IM [Da] Date of entry for processing: 040628 [St] Status: MEDLINE

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[PMID]: 15124089 [Au] Autor: Mbah JA; Tane P; Ngadjui BT; Connolly JD; Okunji CC; Iwu MM; Schuster BM [Ad] Address: Chemistry Department, Faculty of Science, University of Dschang, Dschang, Cameroon. [Ti] Title: Antiplasmodial agents from the leaves of Glossocalyx brevipes. [So] Source: Planta Med;70(5):437-40, 2004 May. [Is] ISSN: 0032-0943 [Cp] Country of publication: Germany [La] Language: eng [Ab] Abstract: A phytochemical study of the methylene chloride/methanol (1/1) extract of the leaves of Glossocalyx brevipes Benth. (Monimiaceae) afforded three new derivatives of homogentisic acid, methyl 2-(1'beta-geranyl-5'beta-hydroxy-2'-oxocyclohex-3'-enyl)acetate (1), 2-(1'beta-geranyl-5'beta-hydroxy-2'-oxocyclohex-3'-enyl)acetic acid (2), methyl 2-(1'beta-geranyl-5'beta-hydroxy-4'beta-methoxy-2'-oxocyclohexyl)acetate (3), and two known alkaloids, aristololactam BII and liriodenine. Compounds 1 and 2 and liriodenine showed modest in vitro activity against Plasmodium falciparum. [Mh] MeSH terms primary: Antiprotozoal Agents/pharmacology Lauraceae Phytotherapy Plant Extracts/pharmacology Plasmodium falciparum/drug effects [Mh] MeSH terms secundary: Animals Antiprotozoal Agents/administration & dosage Antiprotozoal Agents/therapeutic use Humans Parasitic Sensitivity Tests Plant Extracts/administration & dosage Plant Extracts/therapeutic use Plant Leaves [Pt] Publication type: JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, P.H.S. [Nm] Name of substance: 0 (Antiprotozoal Agents); 0 (Plant Extracts) [Em] Entry month: 0408 [Cu] Class update date: 071114 [Lr] Last revision date: 071114 [Js] Journal subset: IM [Da] Date of entry for processing: 040504 [St] Status: MEDLINE

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