Database : MEDLINE
Search on : Musculoskeletal and Diseases [Words]
References found : 25799 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 2580 go to page                         

  1 / 25799 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29506540
[Au] Autor:Kromann AB; Ousager LB; Ali IKM; Aydemir N; Bygum A
[Ad] Address:Department of Dermatology and Allergy Centre, J.B. Winsløws Vej 4 , Entrance 142, 5000, Odense C, Denmark.
[Ti] Title:Pigmentary mosaicism: a review of original literature and recommendations for future handling.
[So] Source:Orphanet J Rare Dis;13(1):39, 2018 Mar 05.
[Is] ISSN:1750-1172
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Pigmentary mosaicism is a term that describes varied patterns of pigmentation in the skin caused by genetic heterogeneity of the skin cells. In a substantial number of cases, pigmentary mosaicism is observed alongside extracutaneous abnormalities typically involving the central nervous system and the musculoskeletal system. We have compiled information on previous cases of pigmentary mosaicism aiming to optimize the handling of patients with this condition. Our study is based on a database search in PubMed containing papers written in English, published between January 1985 and April 2017. The search yielded 174 relevant and original articles, detailing a total number of 651 patients. RESULTS: Forty-three percent of the patients exhibited hyperpigmentation, 50% exhibited hypopigmentation, and 7% exhibited a combination of hyperpigmentation and hypopigmentation. Fifty-six percent exhibited extracutaneous manifestations. The presence of extracutaneous manifestations in each subgroup varied: 32% in patients with hyperpigmentation, 73% in patients with hypopigmentation, and 83% in patients with combined hyperpigmentation and hypopigmentation. Cytogenetic analyses were performed in 40% of the patients: peripheral blood lymphocytes were analysed in 48%, skin fibroblasts in 5%, and both analyses were performed in 40%. In the remaining 7% the analysed cell type was not specified. Forty-two percent of the tested patients exhibited an abnormal karyotype; 84% of those presented a mosaic state and 16% presented a non-mosaic structural or numerical abnormality. In patients with extracutaneous manifestations, 43% of the cytogenetically tested patients exhibited an abnormal karyotype. In patients without extracutaneous manifestations, 32% of the cytogenetically tested patients exhibited an abnormal karyotype. CONCLUSION: We recommend a uniform parlance when describing the clinical picture of pigmentary mosaicism. Based on the results found in this review, we recommend that patients with pigmentary mosaicism undergo physical examination, highlighting with Wood's light, and karyotyping from peripheral blood lymphocytes and skin fibroblasts. It is important that both patients with and without extracutaneous manifestations are tested cytogenetically, as the frequency of abnormal karyotype in the two groups seems comparable. According to the results only a minor part of patients, especially those without extracutaneous manifestations, are tested today reflecting a need for change in clinical practice.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review
[do] DOI:10.1186/s13023-018-0778-6

  2 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29522440
[Au] Autor:Hegewald J; Berge W; Heinrich P; Staudte R; Freiberg A; Scharfe J; Girbig M; Nienhaus A; Seidler A
[Ad] Address:Institute and Policlinic of Occupational and Social Medicine, Faculty of Medicine, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany. janice.hegewald@tu-dresden.de.
[Ti] Title:Do Technical Aids for Patient Handling Prevent Musculoskeletal Complaints in Health Care Workers?-A Systematic Review of Intervention Studies.
[So] Source:Int J Environ Res Public Health;15(3), 2018 Mar 09.
[Is] ISSN:1660-4601
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:The physical load ensuing from the repositioning and moving of patients puts health care workers at risk of musculoskeletal complaints. Technical equipment developed to aid with patient handling should reduce physical strain and workload; however, the efficacy of these aids in preventing musculoskeletal disorders and complaints is still unclear. A systematic review of controlled intervention studies was conducted to examine if the risk of musculoskeletal complaints and disorders is reduced by technical patient handling equipment. MEDLINE /PubMed , EMBASE , Allied and Complementary Medicine Database (AMED), and Cumulative Index of Nursing and Allied Health Literature (CINAHL ) were searched using terms for nursing, caregiving, technical aids, musculoskeletal injuries, and complaints. Randomized controlled trials and controlled before-after studies of interventions including technical patient handling equipment were included. The titles and abstracts of 9554 publications and 97 full-texts were screened by two reviewers. The qualitative synthesis included one randomized controlled trial (RCT) and ten controlled before-after studies. A meta-analysis of four studies resulted in a pooled risk ratio for musculoskeletal injury claims (post-intervention) of 0.78 (95% confidence interval 0.68-0.90). Overall, the methodological quality of the studies was poor and the results often based on administrative injury claim data, introducing potential selection bias. Interventions with technical patient handling aids appear to prevent musculoskeletal complaints, but the certainty of the evidence according to GRADE approach ranged from low to very low.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review

  3 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy

[PMID]: 29446289
[Au] Autor:Sudeikina NA; Kurenkova GV; Lemeshevskaya EP
[Ti] Title:[The impact of harmful occupational factors on the morbidity rate of workers of the railway-car repair plant].
[So] Source:Gig Sanit;95(12):1150-4, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The rail transport is the one of the leading sectors of the national economy. More than 50% of the employees of the enterprises of the railway complex work under the unfavourable impact of hazardous and dangerous substances and occupational factors. In the literature issues of working conditions and health of employees of railway carrepairing plant are hardly highlighted. The aim of the study is the evaluation of the morbidity rate shaped under the influence of harmful occupational factors for the elaboration of preventive measures. In the work there were used generally accepted methods of hygienic studies, analysis of morbidity rate with temporary disability (TD), according to records of periodic medical examinations, occupational prevalence. The railway car-repairing plant was established to be characterized by the complex of harmful factors of the working environment and labor process: noise, local vibration, industrial aerosols of complex composition, chemicals, low light, hardness of the labor process. The levels of incidence with temporal disability in the studied groups, depending on the work seniority in the harmful labor conditions, significantly decrease with the experience from 5 to 9 years and increase with the experience more than 10 years. Executed in-depth analysis as of the both morbidity rate and TD, as well results of periodic medical examinations of workers of main shops shows that overall indices of the morbidity rate and TD are significantly higher than in the comparison group; levels of the morbidity rate and TD in the observed groups significantly decline depending on the length of service in hazardous working conditions with a length of the experience offrom 5 to 9 years and increase with the increase in the length of experience of 10 years or more. In the structure of morbidity and TD leading positions are occupied by diseases of the respiratory system, musculoskeletal system and connective tissue, circulatory system and digestive system, diseases of the eye and its appendages. The health damage risk coefficients in the studied groups of workers and the average losses of working time due to the morbidity with TD per 1 employee in all shops are higher than those in the comparison group. The level of the occupational morbidity rate is very low. Harmful working conditions contribute to the development of general and occupationally related diseases.
[Mh] MeSH terms primary: Industry
Occupational Diseases
Railroads
[Mh] MeSH terms secundary: Humans
Incidence
Industry/methods
Industry/standards
Industry/statistics & numerical data
Occupational Diseases/epidemiology
Occupational Diseases/etiology
Occupational Diseases/prevention & control
Occupational Exposure/adverse effects
Occupational Exposure/analysis
Occupational Exposure/prevention & control
Railroads/instrumentation
Railroads/methods
Risk Assessment/methods
Risk Assessment/standards
Risk Factors
Siberia/epidemiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180216
[St] Status:MEDLINE

  4 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy

[PMID]: 29446281
[Au] Autor:Shalina TI; Nikolaeva LA; Savchenkov MF; Bykov YN; Manueva RS
[Ti] Title:[Environmental pollution with fluoride compounds and their influence on children health].
[So] Source:Gig Sanit;95(12):1133-7, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:Data of hygienic studies of air and soil during last 20 years have confirmed their correlating relationship with the general morbidity and a group of musculoskeletal diseases in children living in cities with the technogenic pollution of the environment. Their bones were established to grow unevenly and disproportionally, in 76% of children there have been violations in the development and growth of bones. The results of X-ray examination of hand bones in children and adolescents in the Irkutsk and Shelekhov cities are presented. Significant differences in morbidity patterns among children and adolescents including an increased incidence of musculoskeletal diseases by 5.6 in children and by 12 in adolescents have been revealed.
[Mh] MeSH terms primary: Environmental Illness
Fluorine Compounds
Musculoskeletal Diseases
[Mh] MeSH terms secundary: Adolescent
Air Pollutants/adverse effects
Air Pollutants/analysis
Bone Development/drug effects
Bone and Bones/diagnostic imaging
Child
Child Health/standards
Child Health/statistics & numerical data
Child, Preschool
Environmental Exposure/adverse effects
Environmental Exposure/analysis
Environmental Exposure/prevention & control
Environmental Illness/diagnosis
Environmental Illness/epidemiology
Environmental Illness/etiology
Environmental Illness/prevention & control
Female
Fluorine Compounds/adverse effects
Fluorine Compounds/analysis
Follow-Up Studies
Humans
Male
Musculoskeletal Diseases/diagnosis
Musculoskeletal Diseases/epidemiology
Musculoskeletal Diseases/etiology
Musculoskeletal Diseases/prevention & control
Siberia/epidemiology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Air Pollutants); 0 (Fluorine Compounds)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180216
[St] Status:MEDLINE

  5 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29521699
[Au] Autor:Martín-Iglesias D; Antequera-Martín A; Barrios-Blandino A
[Ad] Address:From the Internal Medicine Department, Hospital Universitario de La Princesa, Madrid, Spain.
[Ti] Title:A 62-Year-Old Woman With Fever and Exanthema.
[So] Source:J Clin Rheumatol;, 2018 Mar 07.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1097/RHU.0000000000000740

  6 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518972
[Au] Autor:Dancevic CM; Gibert Y; Berger J; Smith AD; Liongue C; Stupka N; Ward AC; McCulloch DR
[Ad] Address:School of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. carolyn.dancevic@deakin.edu.au.
[Ti] Title:The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation.
[So] Source:Int J Mol Sci;19(3), 2018 Mar 07.
[Is] ISSN:1422-0067
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:The ADAMTS5 metzincin, a secreted zinc-dependent metalloproteinase, modulates the extracellular matrix (ECM) during limb morphogenesis and other developmental processes. Here, the role of ADAMTS5 was investigated by knockdown of zebrafish during embryogenesis. This revealed impaired Sonic Hedgehog (Shh) signaling during somite patterning and early myogenesis. Notably, synergistic regulation of expression by ADAMTS5 and Shh during somite differentiation was observed. These roles were not dependent upon the catalytic activity of ADAMTS5. These data identify a non-enzymatic function for ADAMTS5 in regulating an important cell signaling pathway that impacts on muscle development, with implications for musculoskeletal diseases in which ADAMTS5 and Shh have been associated.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Process

  7 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518078
[Au] Autor:Lee KM; Kang SB; Chung CY; Park MS; Kang DW; Chang CB
[Ad] Address:Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Gyeonggi, South Korea.
[Ti] Title:Factors associated with knee pain in 5148 women aged 50 years and older: A population-based study.
[So] Source:PLoS One;13(3):e0192478, 2018.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: This study was performed to investigate the factors associated with the level of knee pain in a nationally representative sample of noninstitutionalized women aged 50 years or older. METHODS: Women aged 50 years or older were selected and included in the data analyses from the Korean National Health and Nutrition Examination Surveys (2010-2013). Those having malignant diseases or using osteoarthritis medication were excluded. Significant factors associated with the level of knee pain were analyzed using multivariate regression analysis. RESULTS: A total of 5148 women (average age, 62.9 years; standard deviation, 9.3 years) were included. For women without knee osteoarthritis, level of hip pain (p<0.001), presence of back pain (p<0.001), age (p<0.001), and body mass index (BMI) (p<0.001) were found to be significant factors associated with the level of knee pain. For women with knee osteoarthritis, the radiographic grade of knee osteoarthritis (p<0.001), presence of back pain (p<0.001), level of hip pain (p<0.001), presence of depressive symptoms (p<0.001), and BMI (p = 0.026) were the factors significantly associated with the level of knee pain. CONCLUSIONS: Women without knee osteoarthritis tended to report increasing knee pain with increasing age. BMI is considered a significant controllable factor in knee pain in women regardless of the presence of radiographic knee osteoarthritis. The presence of depressive symptoms may aggravate knee pain in women with knee osteoarthritis. Attention needs to be focused on concomitant musculoskeletal problems such as lumbar spinal and hip diseases in women with knee pain.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review
[do] DOI:10.1371/journal.pone.0192478

  8 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29517555
[Au] Autor:Ike R; Baskaran A; Chao J; Concoff AL; Wu CW; Sun B; Brion PH; Arnold EL; Klashman DJ; FitzGerald J; Kalunian KC
[Ti] Title:Prevalence of Crystals in Knee Osteoarthritis: Experience From Patients Undergoing Arthroscopic Procedures.
[So] Source:J Clin Rheumatol;, 2018 Mar 07.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1097/RHU.0000000000000744

  9 / 25799 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29517554
[Au] Autor:Chiowchanwisawakit P; Katchamart W; Osiri M; Narongroeknawin P; Chevaisrakul P; Kitumnuaypong T; Siripaitoon B; Louthrenoo W
[Ti] Title:Effectiveness and Drug Survival of Anti-Tumor Necrosis Factor α Therapies in Patients With Spondyloarthritis: Analysis From the Thai Rheumatic Disease Prior Authorization Registry.
[So] Source:J Clin Rheumatol;, 2018 Mar 07.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: This study aimed to evaluate the long-term effectiveness and safety of the first anti-tumor necrosis factor α therapy (TNFi) and to identify the associated factors of drug discontinuation in patients with spondyloarthritis. METHODS: This was a retrospective cohort study. Patients with spondyloarthritis who were prescribed the first TNFi between December 2009 and October 2014 in the Rheumatic Disease Prior Authorization registry were enrolled. Baseline clinical data were retrieved. The Cox proportional hazards model was used to identify factors associated with discontinuation of drugs. RESULTS: Among 138 patients, 97 had ankylosing spondylitis (AS), and 41 had psoriatic arthritis (PsA). The effectiveness of TNFi in AS and PsA was 55% to 59% at 4 months and 75% to 96% at 3 years, as measured by a 50% decrease in the Bath Ankylosing Spondylitis Disease Activity Index from baseline. For PsA with peripheral arthritis, improvement of the joint count by 50% was observed in 61.8% of patients at 4 months and 100% at 3 years. Survival from TNFi was 63% for AS and 56% for PsA at 3 years. For AS, the factors associated with good response leading to discontinuation of TNFi were baseline patient global assessment 3 to 6/10 (hazard ratio [HR], 6.3) and the use of leflunomide (HR, 6.0) and infliximab (HR, 4.8). A good response (38.5%) was the most common cause of discontinuation of the first TNFi, followed by toxicity (28.2%), nonadherence (20.5%), and lack of effectiveness (12.8%). CONCLUSIONS: Ankylosing spondylitis and PsA responded well to TNFi during the 3-year follow-up. The retention rate was approximately 60% for AS and PsA. A good response to the first TNFi was the most common reason for discontinuation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1097/RHU.0000000000000741

  10 / 25799 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29517553
[Au] Autor:Khmelinskii N; da Silva Dinis J; Teixeira V; Romeu JC
[Ad] Address:From the Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.
[Ti] Title:Pseudotumor of the Odontoid Process in Calcium Pyrophosphate Deposition Disease.
[So] Source:J Clin Rheumatol;, 2018 Mar 07.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1097/RHU.0000000000000739


page 1 of 2580 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information