Database : MEDLINE
Search on : Nevus and of and Ota [Words]
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[PMID]: 29288102
[Au] Autor:Yu W; Zhu J; Yu W; Lyu D; Lin X; Zhang Z
[Ad] Address:Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
[Ti] Title:A split-face, single-blinded, randomized controlled comparison of alexandrite 755-nm picosecond laser versus alexandrite 755-nm nanosecond laser in the treatment of acquired bilateral nevus of Ota-like macules.
[So] Source:J Am Acad Dermatol;, 2017 Dec 27.
[Is] ISSN:1097-6787
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Q-switched alexandrite lasers (QSALs) have been used for the treatment of acquired bilateral nevus of Ota-like macules (ABNOMs). Currently, picosecond alexandrite laser (PSAL) pulses have become available for pigmentary disorders. However, no studies have compared PSAL and QSAL in the treatment of ABNOM. OBJECTIVE: We sought to compare the efficacy and safety of PSAL and QSAL in the treatment of ABNOM. METHODS: Each patient (n = 30) received 3 treatments at 6-month intervals. Matching areas were delimitated on the face of each patient (left/right comparison); 1 side was treated with PSAL and the other side was treated with QSAL. The safety and efficacy of the 2 lasers were determined by visual assessment and self-report from patients 6 months after the final treatment. RESULTS: The PSAL-treated area achieved significantly better clearance (3.73 vs 2.4) with less severe pain (4.47 vs 5.16). The incidence rate of postinflammatory hyperpigmentation was 27.77% and 54.44% for the PSAL and QSAL treatments, respectively, and the duration of postinflammatory hyperpigmentation was 1.32 and 1.74 months, respectively (P < .001). LIMITATIONS: The limitations of our study include the small sample size and the lack of objective evaluation. CONCLUSION: Compared with QSAL, PSAL therapy afforded significantly better clinical outcomes and fewer side effects in the treatment of ABNOM.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

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[PMID]: 29521541
[Au] Autor:Liu Y; Zeng W; Li D; Wang W; Liu F
[Ad] Address:a Laser Cosmetology Center of Department of Dermatology, the Second Hospital , Xi'an Jiaotong University , Xi'an , Shaanxi , China.
[Ti] Title:A retrospective analysis of the clinical efficacies and recurrence of Q-switched Nd:YAG laser treatment of nevus of Ota in 224 Chinese patients.
[So] Source:J Cosmet Laser Ther;:1-5, 2018 Mar 09.
[Is] ISSN:1476-4180
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Nevus of Ota can be treated successfully using the Q-switched (QS) laser; but few studies are long-term retrospective of the efficacy and influencing factor, studies on the recurrence is even less. PURPOSE: Retrospective analysis of the clinical characteristics and recurrence of QS Nd:YAG laser treatment of nevus of Ota in 224 Chinese patients at Laser Cosmetology Center of Department of Dermatology, the Second Hospital, Xi'an Jiaotong University. METHODS: The data of 224 patients with nevus of Ota were analyzed retrospectively, which included the correlation among lesion color, treatment sessions, gender, age, lesion types and effect, and all patients were followed up for 2-10 years. RESULTS: Higher number of treatment sessions that were conducted using the QS Nd:YAG laser system was positively associated with better responses to treatment. 99.11% of patients acquired more than 75% improvement with an average of 3.7 sessions. Only eight patients (3.57%) who had been completely cleared developed recurrence at the same site as before. CONCLUSION: The treatment of nevus of Ota with QS Nd:YAG laser is safe and effective with rare recurrence.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1080/14764172.2018.1444772

  3 / 485 MEDLINE  
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[PMID]: 29314292
[Au] Autor:Grechenig C; Cinotti E; Labeille B; Langmann G; Perrot JL; Schatz O; Tarmann L; Wedrich A; Wackernagel W; Zalaudek I; Haybaeck J; Schwab C
[Ad] Address:Department of Ophthalmology, Medical University of Graz, Graz, Styria, Austria.
[Ti] Title:Examination of the melanocytes of the Nevus of Ota with in vivo reflectance confocal microscopy: 15 cases.
[So] Source:J Eur Acad Dermatol Venereol;, 2018 Jan 05.
[Is] ISSN:1468-3083
[Cp] Country of publication:England
[La] Language:eng
[Pt] Publication type:LETTER
[Em] Entry month:1801
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1111/jdv.14783

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[PMID]: 29449519
[Au] Autor:Shima S; Sato S; Moteki Y; Inoue T; Suzuki K; Niimi Y; Okada Y
[Ad] Address:Department of Neurosurgery, St. Luke's International Hospital.
[Ti] Title:[Supratentorial Meningeal Melanoma with Nevus of Ota:A Case Report].
[So] Source:No Shinkei Geka;46(2):139-145, 2018 Feb.
[Is] ISSN:0301-2603
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:We present a rare case of supratentorial meningeal melanoma associated with ipsilateral nevus of Ota, and a review of the literature. The patient was a 32-year-old man with a right-sided nevus of Ota, presenting with unconsciousness. His CT and MRI scans revealed an extra axial tumor with dural tail signs; no lesion was detected on systemic examination. Intraoperatively, the tumor demonstrated black hyperpigmentation and was histologically diagnosed as malignant melanoma. Following surgery, he received radiotherapy and chemotherapy. For over a year and a half, the patient has shown no recurrence of the lesion.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180216
[Lr] Last revision date:180216
[St] Status:In-Data-Review
[do] DOI:10.11477/mf.1436203690

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[PMID]: 29423841
[Au] Autor:Alegre-Sanchez A; Jiménez-Gómez N; Moreno-Arrones ÓM; Fonda-Pascual P; Pérez-García B; Jaén-Olasolo P; Boixeda P
[Ad] Address:Dermatology Department, Laser Unit, Hospital Universitario Ramón y Cajal, Ctra Colmenar Viejo Km 9,100, 28034, Madrid, Spain. adrian.alegresanchez@gmail.com.
[Ti] Title:Treatment of flat and elevated pigmented disorders with a 755-nm alexandrite picosecond laser: clinical and histological evaluation.
[So] Source:Lasers Med Sci;, 2018 Feb 09.
[Is] ISSN:1435-604X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The novel picosecond lasers, initially developed for faster tattoo removal, have also shown great efficacy in endogenous pigmentary disorders. To describe the efficacy and safety profile of an alexandrite (755-nm) picosecond laser in a wide range of pigmented flat and elevated cutaneous lesions. A retrospective study was performed in which we collected all the clinical images of patients treated with the 755-nm alexandrite picosecond laser for 12 months (November 2016-November 2017). Clinical features were obtained from their medical charts. Patients treated for tattoo removal were excluded. All the images were analyzed by three blind physicians attending to a visual analogue scale (VAS) from 0 to 5 (0, no change; 1, 1-24% clearance; 2, 25-49% clearance; 3, 50-74% clearance; 4, 75-99% clearance; 5, complete clearance). Patient satisfaction was obtained from a subjective survey including four items: very satisfied, satisfied, non-satisfied, and totally dissatisfied. Thirty-seven patients were included (12 males; 25 females). The mean age of the study was 42.35 years. Twenty-five patients (68%) were treated for different pigmented flat disorders such as solar and mucosal lentigines (5), stasis dermatitis (4), or nevus of Ota (4), among other diagnoses. Twelve patients (32%) were treated for epidermal elevated lesions such as warts (5), epidermal nevi (2), and seborrheic keratosis (3), among other elevated lesions. Mean number of laser treatment was 3.02 sessions while mean follow-up after last laser treatment was 4.02 months. Mean VAS score of the three observers was 3.44 (61% of clearance) for pigmentary flat disorders and 3.60 (67%) for elevated lesions. Adverse effects reported were mild blistering in the first 2-5 days following laser treatment in some of the patients. Overall satisfaction among the patients included was high. The novel 755-nm picosecond alexandrite laser is effective not only for the resolution of pigmented flat lesions of different nature but also for the treatment of the more difficult elevated pigmented lesions.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[St] Status:Publisher
[do] DOI:10.1007/s10103-018-2459-z

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[PMID]: 29131366
[Au] Autor:Belkin DA; Jeon H; Weiss E; Brauer JA; Geronemus RG
[Ad] Address:Laser & Skin Surgery Center of New York, 317 East 34th Street, New York, New York, 10016.
[Ti] Title:Successful and safe use of Q-switched lasers in the treatment of nevus of Ota in children with phototypes IV-VI.
[So] Source:Lasers Surg Med;, 2017 Nov 13.
[Is] ISSN:1096-9101
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Nevus of Ota represents congenital dermal melanocytosis in a trigeminal distribution, most commonly occurring in Asian individuals and other individuals with skin of color. Evidence suggests early treatment is beneficial. Multiple reports have shown efficacy and safety of Q-switched laser treatment in adults. There is little data on children and in non-Asian skin types. This series was done to demonstrate safe and effective use of Q-switched laser therapy in children of multiple skin types. STUDY DESIGN: Retrospective case series. METHODS: This was a chart review of patients under 18 years old who presented to our practice from 2002 to 2015 with a clinical diagnosis of nevus of Ota who were treated with Q-switched lasers (694 and 1,064 nm). Patients were treated without the use of general anesthesia or sedation, and corneal shields were used in appropriate cases. Percentage of improvement as well as side effects were rated by five physicians independently. Improvement, when present, was rated in quartiles (1-25%, 26-50%, 51-75%, and 76-100% improvement). RESULTS: Twenty-four children were included. The average age at the start of treatment was 3.9 years old (range of 3 months to 12.4 years), and patients had Fitzpatrick skin types IV through VI. The mean number of treatments was 9.3. Assessment revealed excellent response (76-100% improvement) in 70% of patients and good to excellent response (51-100% improvement) in 86%. Two patients (8%) had post-inflammatory hyperpigmentation, one of whom also had focal hypopigmentation. CONCLUSION: Treatment of nevus of Ota with Q-switched lasers in children with skin of color, without general anesthesia or sedation, is safe and effective. Early intervention should be encouraged for better efficacy and to prevent psychosocial distress in later childhood and adulthood. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171113
[Lr] Last revision date:171113
[St] Status:Publisher
[do] DOI:10.1002/lsm.22757

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[PMID]: 28986651
[Au] Autor:Yan L; Di L; Weihua W; Feng L; Ruilian L; Jun Z; Hui S; Zhaoxia Y; Weihui Z
[Ad] Address:Laser Cosmetology Center of Department of Dermatology, The Second Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China. liuyan95@126.com.
[Ti] Title:A study on the clinical characteristics of treating nevus of Ota by Q-switched Nd:YAG laser.
[So] Source:Lasers Med Sci;, 2017 Oct 07.
[Is] ISSN:1435-604X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The purpose of this study was to retrospectively analyze the clinical characteristics of treating nevus of Ota by Q-switched Nd:YAG laser in Laser Cosmetology Center of Department of Dermatology, the Second Hospital, Xi'an Jiaotong University. The data of 1168 patients of nevus of Ota were analyzed retrospectively, which included the correlation among lesion color, treatment sessions, sex, age, lesion types, and effect. The Q-switched (QS) Nd:YAG laser system had a higher number of treatment sessions which were positively associated with a better response to treatment. Other variables, including gender, age, the categorization of the lesion according to Tanino's classification, and the color of the lesion, were not associated with the response to treatment. The treatment of nevus of Ota with QS Nd:YAG laser is safe and effective, with rare complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171007
[Lr] Last revision date:171007
[St] Status:Publisher
[do] DOI:10.1007/s10103-017-2342-3

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[PMID]: 28932095
[Au] Autor:Nam JH; Kim HS; Choi YJ; Jung HJ; Kim WS
[Ad] Address:Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
[Ti] Title:Erratum: Treatment and Classification of Nevus of Ota: A Seven-Year Review of a Single Institution's Experience.
[So] Source:Ann Dermatol;29(5):666, 2017 Oct.
[Is] ISSN:1013-9087
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:[This corrects the article on p. 446 in vol. 29, PMID: 28761293.].
[Pt] Publication type:PUBLISHED ERRATUM
[Em] Entry month:1709
[Cu] Class update date: 170921
[Lr] Last revision date:170921
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.5021/ad.2017.29.5.666

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[PMID]: 28855482
[Au] Autor:Ono T
[Ad] Address:Kumamoto Kinoh Hospital.
[Ti] Title:Prof. Masao Ota.
[So] Source:Med Mycol J;58(3):J71-J75, 2017.
[Is] ISSN:1882-0476
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:Masao Ota was a Professor of Dermatology at Tokyo Imperial University. He is known to dermatologists around the world as the researcher who identified Nevus of Ota. He is also known for his research on Hansen's Disease. He was critical of the forced isolation policy and the sterilization law. He dreamt of developing chemotherapeutic measures and dedicated himself to cultivating Mycobacterium leprae. Among his accomplishments, those in the area of medical mycology are particularly remarkable. His discovery of Microsporum ferrugineum, his proposal for Trichophytia pompholyciformis, and his work on Ota-Langeron taxonomy based on the findings on fungus colonies are highly regarded and earned him the Ordre Royale de la Legion D'honneur. His accomplishments in the field of mycology are numerous; he has published a total of 39 research papers mostly in foreign languages. He was a leading world-class medical mycologist of his day. This review introduces some of his accomplishments and some episodes in his life.Furthermore, Masao Ota had a detailed knowledge of art and culture. Under the pseudonym of Kinoshita Mokutaro, he wrote poems, plays, and novels. He was also a painter. Particularly, his paintings in botany during his later years were published in the book "One Hundred Flower Sketches" after his death.Ota said, "The consequence of both science and art is global and humanitarian." He was one of the greatest men of culture in his time.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 171015
[Lr] Last revision date:171015
[St] Status:In-Process
[do] DOI:10.3314/mmj.17.009

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[PMID]: 28831422
[Au] Autor:LaRosa C; Chiaravalloti A; Jinna S; Berger W; Finch J
[Ad] Address:Department of Dermatology, University of Connecticut School of Medicine, Farmington, CT.
[Ti] Title:Laser treatment of medical skin disease in women.
[So] Source:Int J Womens Dermatol;3(3):131-139, 2017 Sep.
[Is] ISSN:2352-6475
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Laser treatment is a relatively new and increasingly popular modality for the treatment of many dermatologic conditions. A number of conditions that predominantly occur in women and that have a paucity of effective treatments include rosacea, connective tissue disease, melasma, nevus of Ota, lichen sclerosus (LS), notalgia paresthetica and macular amyloidosis, and syringomas. Laser therapy is an important option for the treatment of patients with these conditions. This article will review the body of literature that exists for the laser treatment of women with these medical conditions.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1708
[Cu] Class update date: 170827
[Lr] Last revision date:170827
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1016/j.ijwd.2017.05.002


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