Database : MEDLINE
Search on : Nuphar [Words]
References found : 113 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 12 go to page                         

  1 / 113 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29441664
[Au] Autor:Souffreau C; Busschaert P; Denis C; Van Wichelen J; Lievens B; Vyverman W; De Meester L
[Ad] Address:Laboratory of Aquatic Ecology, Evolution & Conservation, KU Leuven, Leuven, Belgium.
[Ti] Title:A comparative hierarchical analysis of bacterioplankton and biofilm metacommunity structure in an interconnected pond system.
[So] Source:Environ Microbiol;, 2018 Feb 14.
[Is] ISSN:1462-2920
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:It is unknown whether bacterioplankton and biofilm communities are structured by the same ecological processes, and whether they influence each other through continuous dispersal (known as mass effects). Using a hierarchical sampling approach we compared the relative importance of ecological processes structuring the dominant fraction (relative abundance ≥0.1%) of bacterioplankton and biofilm communities from three microhabitats (open water, Nuphar and Phragmites sites) at within- and among-pond scale in a set of 14 interconnected shallow ponds. Our results demonstrate that while bacterioplankton and biofilm communities are highly distinct, a similar hierarchy of ecological processes is acting on them. For both community types, most variation in community composition was determined by pond identity and environmental variables, with no effect of space. The highest ß-diversity within each community type was observed among ponds, while microhabitat type (Nuphar, Phragmites, open water) significantly influenced biofilm communities but not bacterioplankton. Mass effects among bacterioplankton and biofilm communities were not detected, as suggested by the absence of within-site covariation of biofilm and bacterioplankton communities. Both biofilm and plankton communities were thus highly structured by environmental factors (i.e. species sorting), with among-lake variation being more important than within-lake variation, whereas dispersal limitation and mass effects were not observed. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180214
[Lr] Last revision date:180214
[St] Status:Publisher
[do] DOI:10.1111/1462-2920.14073

  2 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29147807
[Au] Autor:Ivanova AA; Philippov DA; Kulichevskaya IS; Dedysh SN
[Ad] Address:Winogradsky Institute of Microbiology, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia, 119071.
[Ti] Title:Distinct diversity patterns of Planctomycetes associated with the freshwater macrophyte Nuphar lutea (L.) Smith.
[So] Source:Antonie Van Leeuwenhoek;, 2017 Nov 17.
[Is] ISSN:1572-9699
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Members of the phylum Planctomycetes were originally described as freshwater bacteria. Most recent studies, however, address planctomycete diversity in other environments colonized by these microorganisms, including marine and terrestrial ecosystems. This study was initiated in order to revisit the specific patterns of planctomycete diversity in freshwater habitats using cultivation-independent approaches. The specific focus was made on planctomycetes associated with Nuphar lutea (L.) Smith, an emergent macrophyte with floating leaves, which is widespread in the Holarctic. As revealed by Illumina pair-end sequencing of 16S rRNA gene fragments, the bacterial assemblages colonizing floating leaf blades of waterlilies sampled from two different boreal lakes displayed similar composition but were distinct from the planktonic bacterial communities. 16S rRNA gene fragments from the Planctomycetes comprised 0.1-1 and 1-2.2% of total 16S rRNA gene reads retrieved from water samples and plant leaves, respectively. Planktonic planctomycetes were mostly affiliated with the class Planctomycetaceae (77-97%), while members of the Phycisphaerae were less abundant (3-22%). The relative proportion of the latter group, however, increased by 13-45% on leaves of N. lutea. The Phycisphaera-related group WD2101, Pirellula-like planctomycetes, as well as Gemmata, Zavarzinella and Planctopirus species were the most abundant groups of planctomycetes associated with plant leaves, which may suggest their involvement in the degradation of plant-derived organic matter.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171117
[Lr] Last revision date:171117
[St] Status:Publisher
[do] DOI:10.1007/s10482-017-0986-4

  3 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28911224
[Au] Autor:Lacharity JJ; Fournier J; Lu P; Mailyan AK; Herrmann AT; Zakarian A
[Ad] Address:Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
[Ti] Title:Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly.
[So] Source:J Am Chem Soc;139(38):13272-13275, 2017 Sep 27.
[Is] ISSN:1520-5126
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:An asymmetric total synthesis of (+)-6-hydroxythiobinupharidine (1b) and (-)-6-hydroxythionuphlutine (2b), a set of hemiaminal containing dimeric sesquiterpenes isolated from yellow water lilies of the Nuphar genus, is described. The central bis-spirocyclic tetrahydrothiophene ring was forged through the Stevens rearrangement of a sulfonium ylide, generated in situ from the coupling of a copper-carbene with a spirocyclic thietane. This strategy diverges both from the proposed biosynthesis1 and previous syntheses of this family of alkaloids,2,3 all of which employ dimerization of symmetric monomers to form the aforementioned thiaspirane. The coupling of unsymmetrical monomers allowed access to the unsymmetrically oxidized product 2b for the first time.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170927
[Lr] Last revision date:170927
[St] Status:In-Data-Review
[do] DOI:10.1021/jacs.7b07685

  4 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28638458
[Au] Autor:Ozer J; Fishman D; Eilam B; Golan-Goldhirsh A; Gopas J
[Ad] Address:The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences Ben-Gurion University of the Negev, Beer Sheva, Israel.
[Ti] Title:Anti-Metastatic Effect of Semi-Purified Leaf Extracts.
[So] Source:J Cancer;8(8):1433-1440, 2017.
[Is] ISSN:1837-9664
[Cp] Country of publication:Australia
[La] Language:eng
[Ab] Abstract:L. SM., leaf and rhizome extracts (NUP), contain nupharidines as active components. Nupharidines belong to the sesquiterpene lactones class of a naturally occurring plant terpenoids. This family of compounds has gained considerable interest for treating infection, inflammation and cancer. NF-κB is a central, downstream regulator of inflammation, cell proliferation and apoptosis. In our previous work we demonstrated strong inhibition of NF-κB activity and induction of apoptosis by NUP. In addition, NUP exhibited anti-inflammatory properties and partial protection from LPS-induced septic shock by modulating ERK pathway and cytokine secretion in macrophages. In the present study, we examined the effect of NUP in a B16 melanoma experimental murine lung metastasis model and its ability to affect the ERK and NF-κB pathways in variety of cell lines. We showed that NUP and cisplatin combined treatment was synergistic and reduced the lung metastatic load. In addition NUP treatment inhibited TNFα-induced IκBα degradation and NF- κB nuclear translocation We also observed that NUP induced ERK activation. Furthermore, ERK inhibition prevented NF-κB inactivation by NUP. Overall, our work implies that co-administration of NF-κB inhibitors such as NUP, with standard anti-cancer drugs, may act as "sensitizers" for more effective chemotherapy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 170816
[Lr] Last revision date:170816
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.7150/jca.18435

  5 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28335791
[Au] Autor:Kujawska M; Klepacki P; Luczaj L
[Ad] Address:Institute of Ethnology and Cultural Anthropology, University of Lódz, Lindleya 3/5, 90-131, Lódz, Poland. monika.kujawska@uni.lodz.pl.
[Ti] Title:Fischer's Plants in folk beliefs and customs: a previously unknown contribution to the ethnobotany of the Polish-Lithuanian-Belarusian borderland.
[So] Source:J Ethnobiol Ethnomed;13(1):20, 2017 Mar 23.
[Is] ISSN:1746-4269
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Historical ethnobotanical studies are useful starting points for further diachronic analysis. The aim of this contribution is to present archival data from the Polish-Lithuanian-Belarusian borderland, which were collected by Adam Fischer, a Polish ethnographer from Lviv, in the 1930s. These data were originally gathered for publication in the first part of the Lexicon of Slavic beliefs and customs, dedicated to plant uses in traditional Slavonic culture. It was intended to be a joint international enterprise, but was never actually fulfilled. METHODS: In this article we used information from historical Lithuania (the Great Duchy of Lithuania), nowadays a border region between Poland, Lithuania and Belarus. We applied cultural importance indices such as Use Value, Relative Importance value and Sørensen similarity coefficient, in order to compare our data with a western Ukraine data set from the same research framework. RESULTS: In total, 153 plant taxa were registered as used in peasant culture in the Polish-Lithuanian-Belarusian borderland in the 1930s. The species which achieved the highest Use Values were: Calendula officinalis, Cyanus segetum, Helichrysum arenarium, Betula sp., Prunella vulgaris, and Nuphar lutea or Lilium sp. The most salient use categories were medicinal, followed by food and home garden plants. The overall similarity to plants recorded in western Ukraine within the same project of Fischer's is quite low (46%), which may be explained by the partly different flora found in the regions, and a cultural discontinuity, revealed by the difference in species with the highest UV. Moreover, the field collaborators were different in the two regions and may have paid attention to different cultural spheres of use. CONCLUSIONS: The presented ethnobotanical data are a valuable contribution to the ethnobotany of Eastern Europe as a whole. In particular, the presented list of plants may be a rich source for future studies on the ethnobotany of the Polish diaspora in Lithuania, and diachronic studies in north-east Poland and Belarus.
[Mh] MeSH terms primary: Ethnobotany/history
Medicine, Traditional/history
[Mh] MeSH terms secundary: Ethnobotany/methods
Food
History, 20th Century
Humans
Lithuania
Medicine, Traditional/methods
Plants, Medicinal
Poland
[Pt] Publication type:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Personal name as subject:Fischer A
[Em] Entry month:1709
[Cu] Class update date: 170920
[Lr] Last revision date:170920
[Js] Journal subset:IM
[Da] Date of entry for processing:170325
[St] Status:MEDLINE
[do] DOI:10.1186/s13002-017-0149-8

  6 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28164703
[Au] Autor:Li H; Cooke TJ; Korotkov A; Chapman CW; Eastman A; Wu J
[Ad] Address:Department of Chemistry, Dartmouth College , Hanover, New Hampshire 03755, United States.
[Ti] Title:Stereoselective Synthesis and Biological Evaluation of C1-Epimeric and Desmethyl Monomeric Nuphar Analogues.
[So] Source:J Org Chem;82(5):2648-2655, 2017 Mar 03.
[Is] ISSN:1520-6904
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A class of monomeric nuphar analogues that are either epimeric at C1 and C1' or lack the naturally occurring methyl group at those positions were synthesized and evaluated for biological activity. The syntheses feature enantioselective vinylogous Mukaiyama-Mannich (vM-Mannich) reactions catalyzed by chiral phosphoric acids that proceed with excellent diastereoselectivity. Biological assays reveal that both the desmethyl and C1-epimeric monomeric nuphar analogous are able to induce rapid apoptosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1702
[Cu] Class update date: 170303
[Lr] Last revision date:170303
[St] Status:In-Data-Review
[do] DOI:10.1021/acs.joc.6b03052

  7 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 27878469
[Au] Autor:Shiga T; Yokogawa M; Kaneko S; Isagi Y
[Ad] Address:Faculty of Education, Niigata University, Ikarashi-Ninocho, Nishi-ku, Niigata, 950-2181, Japan. shiga@ed.niigata-u.ac.jp.
[Ti] Title:Genetic diversity and population structure of Nuphar submersa (Nymphaeaceae), a critically endangered aquatic plant endemic to Japan, and implications for its conservation.
[So] Source:J Plant Res;130(1):83-93, 2017 Jan.
[Is] ISSN:1618-0860
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Nuphar submersa (Nymphaeaceae) is a critically endangered freshwater macrophyte indigenous to central Japan, with only four small extant populations represented across its entire range. We investigated the genotypic and genetic diversity as well as the genetic structure of all extant individuals of N. submersa based on analysis of 15 microsatellite loci. Among 278 individual ramets, 52 multilocus genotypes were detected: 30 genotypes in Nikko City (NIK), 18 in Nasukarasuyama City (NAS), 3 in Mooka City (MOK), and 1 in Sakura City (SAK). The average number of alleles per locus ranged from 1.20 to 1.93, whereas the observed and expected heterozygosities ranged from 0.11 to 0.33 and from 0.10 to 0.24, respectively. With the exception of SAK, all populations contained multiple clones, but our results indicated low levels of within-population genetic diversity. The populations NIK and NAS comprised few large or middle-sized genets and many small genets. The populations NIK and NAS were suggested to comprise large old, old fragmented, and/or young small genets resulting from seedling establishment. All four populations were differentiated, and gene flow between the populations was restricted (average level of gene flow (Nm) = 0.122, G'  = 0.639). Of the total genetic diversity, 67.20 and 9.13% were attributable to inter- and intra-population diversity, respectively. STRUCTURE analysis revealed two or three well-differentiated groups of populations. Cluster I comprised one population (NIK) and cluster II comprised the remaining populations at K = 2. The populations NIK, NAS, and the remaining populations were assigned to clusters I, II, and III, respectively, at K = 3. For conservation practices, we recommend that each cluster be regarded as a different management unit. We further suggest that artificial gene flow among MOK and SAK populations is an appropriate option, whereas NIK should not be reinforced with genotypes from the remaining populations.
[Mh] MeSH terms primary: Genetic Variation
Nuphar/genetics
[Mh] MeSH terms secundary: Alleles
Animals
Conservation of Natural Resources
Endangered Species
Gene Flow
Genetic Loci/genetics
Genetics, Population
Genotype
Japan
Microsatellite Repeats/genetics
Nuphar/physiology
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1705
[Cu] Class update date: 171014
[Lr] Last revision date:171014
[Js] Journal subset:IM
[Da] Date of entry for processing:161124
[St] Status:MEDLINE
[do] DOI:10.1007/s10265-016-0869-1

  8 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28101435
[Au] Autor:Kondo T; Watanabe S; Shiga T; Isagi Y
[Ad] Address:Graduate School for International Development and Cooperation, Hiroshima University, Higashi-Hiroshima 739-8529, Japan.
[Ti] Title:Microsatellite markers for (Nymphaeaceae), an aquatic plant in the agricultural ecosystem of Japan.
[So] Source:Appl Plant Sci;4(12), 2016 Dec.
[Is] ISSN:2168-0450
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PREMISE OF THE STUDY: species (Nymphaeaceae) are representative aquatic plants in irrigation ponds in Japanese agricultural ecosystems. We developed 15 polymorphic microsatellite markers for and confirmed their utility for its close relatives var. and . × , which originated from natural hybridization between and . METHODS AND RESULTS: Genetic variation was characterized in 15 polymorphic loci in three populations of . The average number of alleles per locus was 3.47 (range = 2-9; = 32), and the average expected heterozygosity per locus was 0.84 (range = 0.5-1.0); 11 loci were amplified in var. and 15 in . × . CONCLUSIONS: The polymorphic microsatellite markers developed in this study will be useful for investigating the levels of genetic diversity within remnant populations of taxa and could provide a valuable tool for conservation genetics of these taxa.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1701
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[St] Status:PubMed-not-MEDLINE

  9 / 113 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 27413784
[Au] Autor:Tada N; Jansen DJ; Mower MP; Blewett MM; Umotoy JC; Cravatt BF; Wolan DW; Shenvi RA
[Ad] Address:Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
[Ti] Title:Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore.
[So] Source:ACS Cent Sci;2(6):401-8, 2016 Jun 22.
[Is] ISSN:2374-7943
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We describe a general method to synthesize the iminium tetrahydrothiophene embedded in the dimeric Nuphar alkaloids. In contrast to prior studies, the sulfur atom of the thiaspirane pharmacophore is shown to be electrophilic. This α-thioether reacts with thiophenol or glutathione at ambient temperature to cleave the C-S bond and form a disulfide. Rates of conversion are proportional to the corresponding ammonium ion pK a and exhibit half-lives less than 5 h at a 5 mM concentration of thiol. A simple thiophane analogue of the Nuphar dimers causes apoptosis at single-digit micromolar concentration and labels reactive cysteines at similar levels as the unsaturated iminium "warhead". Our experiments combined with prior observations suggest the sulfur of the Nuphar dimers can react as an electrophile in cellular environments and that sulfur-triggered retrodimerization can occur in the cell.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1607
[Cu] Class update date: 170923
[Lr] Last revision date:170923
[Da] Date of entry for processing:160715
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1021/acscentsci.6b00113

  10 / 113 MEDLINE  
              first record previous record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 27413779
[Au] Autor:Marcaurelle LA; Mulvihill MJ
[Ad] Address:Warp Drive Bio, Inc. , 400 Technology Square, Cambridge, Massachusetts 02139, United States.
[Ti] Title:Nuphar Dimers: Crouching Sulfur, Hidden Reactivity.
[So] Source:ACS Cent Sci;2(6):367-9, 2016 Jun 22.
[Is] ISSN:2374-7943
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:NEWS
[Em] Entry month:1607
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:160715
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1021/acscentsci.6b00166


page 1 of 12 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information