Database : MEDLINE
Search on : Nyctaginaceae [Words]
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[PMID]: 29421242
[Au] Autor:Li X; Yin M; Yang X; Yang G; Gao X
[Ad] Address:School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
[Ti] Title:Flavonoids from Mirabilis himalaica.
[So] Source:Fitoterapia;, 2018 Feb 05.
[Is] ISSN:1873-6971
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Six previously undescribed flavonoids, 2S-5-methoxy-6-methyl-7,2'-dihydroxyflavanone, 5,7,2'-trihydroxy-6-methylflavone, 5,7,6'-trihydroxy-6-methylcoumaronochromone, 2,4',6'-trihydroxy-2'-methoxy-3'-methylchalcone, 6R,11-dimethoxy-9-hydroxyrotenoid, and 6R,11-dimethoxy-9-hydroxy-10-methylrotenoid, along with eight known flavonoids, including 2S-5-methoxy-6-methyl-7,4'-dihydroxyflavanone, not previously reported as a natural product, and seven rotenoids, boeravinone A, B, D, P, F, coccineone B, and mirabijalone E, were isolated from the ethyl acetate soluble fraction of Mirabilis himalaica roots. Their structures were established by the extensive spectroscopic analysis, including HRESIMS, UV, NMR and ECD. All compounds were evaluated for their cytotoxic activities against three human cancer cell lines: A375 (melanoma), A549 (lung), and PLC (hepatoma).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180208
[Lr] Last revision date:180208
[St] Status:Publisher

  2 / 160 MEDLINE  
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[PMID]: 29158698
[Au] Autor:Caraballo-Ortiz MA; Trejo-Torres JC
[Ad] Address:The Pennsylvania State University, Department of Biology, 208 Mueller Laboratory, University Park, Pennsylvania, 16802, USA.
[Ti] Title:Two new endemic tree species from Puerto Rico: and (Nyctaginaceae).
[So] Source:PhytoKeys;(86):97-115, 2017.
[Is] ISSN:1314-2011
[Cp] Country of publication:Bulgaria
[La] Language:eng
[Ab] Abstract:In this paper, we describe two endemic tree species of (Caryophyllales: Nyctaginaceae) from Puerto Rico that were erroneously catalogued under the single name Pisonia subcordata var. typica f. gigantophylla, misidentified as or , and informally named as " " and " ". The species here named as is a rare to locally occasional tree from low elevations in the Northern Karst and the Sierra de Cayey. The other species, here named as , is a rare to locally common tree from mid to high elevations in the Central Mountain Range and the Luquillo Mountains. We provide an account of the taxonomical and nomenclatural history of both species, images, conservation notes, a distribution map, and a key to distinguish the species of present in Puerto Rico.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171123
[Lr] Last revision date:171123
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3897/phytokeys.86.11249

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[PMID]: 28887472
[Au] Autor:Filippov AE; Gorb EV; Gorb SN
[Ad] Address:Department of Functional Morphology and Biomechanics, Zoological Institute, Kiel University, Am Botanischen Garten 9, D-24118, Kiel, Germany.
[Ti] Title:Radial arrangement of apical adhesive sites promotes contact self-alignment of fruits in Commicarpus plants (Nyctaginaceae).
[So] Source:Sci Rep;7(1):10956, 2017 Sep 08.
[Is] ISSN:2045-2322
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Fruits of the plants from the genus Commicarpus (Nyctaginaceae) use their adhesive properties for dispersal. They can readily stick to various surfaces including skin, fur, and feathers of potential dispersal vectors using the secretion provided by the set of glands arranged radially at the distal end of the cut-cone-shaped fruit. Field observations show that this particular geometry promotes self-alignment of the fruit to various surfaces after initial contact just by one gland is established. Such self-alignment in turn leads to an increase of the number of contacting points and to the enhancement of adhesive contact area. Here, we study this particular geometry from a theoretical point of view, by probing adhesion ability of geometries having from 2 to 7 radially distributed attachment points. The results show that the radial arrangement provides rapid alignment to the surface. The robust adhesion can be reached already at 5 adhesive points and their further increase does not substantially improve the performance. This study is important not only for our understanding of the functional morphology of biological adhesive systems, but also for the development of technical self-aligning adhesive devices.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170914
[Lr] Last revision date:170914
[St] Status:In-Data-Review
[do] DOI:10.1038/s41598-017-10567-9

  4 / 160 MEDLINE  
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[PMID]: 28503048
[Au] Autor:Ghogar A; Jiraungkoorskul W
[Ad] Address:Mahidol University International College, Mahidol University, Salaya Campus, Nakhon Pathom, Thailand.
[Ti] Title:Antifertility Effect of or Paper Flower.
[So] Source:Pharmacogn Rev;11(21):19-22, 2017 Jan-Jun.
[Is] ISSN:0973-7847
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:(Family: Nyctaginaceae), commonly referred to as Great or Paper Flower, is one of the traditional medicinal plants with potential antifertility activity. The aqueous extract and decoction of this plant have been used as fertility control among the tribal people in many countries. Furthermore, it has been shown to possess anticancer, antidiabetic, antihepatotoxic, anti-inflammatory, antihyperlipidemic, antimicrobial, antioxidant, and antiulcer properties. Its phytoconstituents such as alkaloids, essential oils, flavonoids, glycosides, oxalates, phenolics, phlobotannins, quinones, saponins, tannins, and terpenoids were reported as the basis of its efficacious therapeutic properties. The other important constituents which contribute to the remedial properties are bougainvinones, pinitol, quercetagetin, quercetin, and terpinolene. Published information on the antifertility property of was gathered by the use of different database platforms including Google Scholar, ScienceDirect, PubMed, SciFinder, and Scopus. These database platforms were used to provide an up-to-date review on its importance.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1705
[Cu] Class update date: 170816
[Lr] Last revision date:170816
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.4103/phrev.phrev_44_16

  5 / 160 MEDLINE  
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[PMID]: 28337741
[Au] Autor:Bose M; Kamra M; Mullick R; Bhattacharya S; Das S; Karande AA
[Ad] Address:Department of Biochemistry, Indian Institute of Science, Bangalore, India.
[Ti] Title:A plant-derived dehydrorotenoid: a new inhibitor of hepatitis C virus entry.
[So] Source:FEBS Lett;591(9):1305-1317, 2017 May.
[Is] ISSN:1873-3468
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Emergence of drug-resistant viruses, high cost and adverse side-effects associated with the standard therapy against hepatitis C virus (HCV) infection demonstrate the need for development of well tolerated and effective antivirals. We identified and chemically characterised the dehydrorotenoid boeravinone H, isolated from the herb Boerhavia diffusa, as a new inhibitor of HCV entry. The compound significantly inhibits the binding and entry of hepatitis C-like particles (HCV-LPs) in hepatoma cells in vitro with no apparent cytotoxicity. Boeravinone H inhibits the initial phase of HCV entry probably by acting directly on the viral particle. Importantly, the compound prevents HCV entry and infection in cell culture (ex vivo). Thus, boeravinone H is a potential antiviral agent for the prevention and control of HCV infection.
[Mh] MeSH terms primary: Flavonoids/pharmacology
Hepacivirus/drug effects
Plant Extracts/pharmacology
Virus Internalization/drug effects
[Mh] MeSH terms secundary: Carcinoma, Hepatocellular/pathology
Carcinoma, Hepatocellular/virology
Cell Line, Tumor
Cell Survival/drug effects
Dose-Response Relationship, Drug
Flavonoids/chemistry
Hepacivirus/physiology
Host-Pathogen Interactions/drug effects
Humans
Liver Neoplasms/pathology
Liver Neoplasms/virology
Microscopy, Confocal
Microscopy, Fluorescence
Molecular Structure
Nyctaginaceae/chemistry
Plant Extracts/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Flavonoids); 0 (Plant Extracts); 0 (dehydrorotenone)
[Em] Entry month:1709
[Cu] Class update date: 170918
[Lr] Last revision date:170918
[Js] Journal subset:IM
[Da] Date of entry for processing:170325
[St] Status:MEDLINE
[do] DOI:10.1002/1873-3468.12629

  6 / 160 MEDLINE  
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[PMID]: 28163967
[Au] Autor:Fred-Jaiyesimi A; Taiwo J
[Ad] Address:Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun, Nigeria.
[Ti] Title:Pregnancy detecting plants used in Remo and Ijebu areas of Ogun State, Nigeria.
[So] Source:J Intercult Ethnopharmacol;6(1):102-106, 2017 Jan-Mar.
[Is] ISSN:2146-8397
[Cp] Country of publication:Turkey
[La] Language:eng
[Ab] Abstract:AIM/BACKGROUND: Plants and plants extracts are employed in cultures for religious purposes, as beauty therapies, in the detection and management/treatment of diseases. MATERIALS AND METHODOLOGY: In this study, an ethnobotanical studies of plants used in detecting pregnancy in Ijebu and Remo areas of Ogun State were carried out using semi-structured to obtain demographic data, local names of plants, the morphological parts used. Furthermore, a phytochemical analysis of two of the identified plants was performed. Topical and urine tests of plants in detecting pregnancy were designed to mimic procedures used in traditional medicine for detecting pregnancy. RESULTS: Five plant species were identified belonging to the families Araceae, Asteraceae, Convolvulaceae, Nyctaginaceae, and Rubiaceae in the survey. The identified plants had the use value (UV) of 0.25 ( ), 0.17 ( ), while and had the UV of 0.08, respectively. L, (Schumach) Hepper tested positive for the presence of flavonoids, alkaloids, and tannins. The onset and duration of symptoms of both and leaves at 2000 and 1000 mg were dose-dependent. The hexane, ethyl acetate, and ethanol extracts of and exhibited pruritus and restlessness in the model while the urine of pregnant women caused black spots on the leaves of (Willd) Amin Ex. C. Jeffrey. CONCLUSION: This study reports a rare knowledge of using plants in detecting pregnancy in the Remo and Ijebu areas of Ogun State, Nigeria.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1702
[Cu] Class update date: 170816
[Lr] Last revision date:170816
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.5455/jice.20161128114459

  7 / 160 MEDLINE  
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[PMID]: 28068633
[Au] Autor:A P; Varghese MV; S A; P SR; Mathew AK; Nair A; Nair RH; K G R
[Ad] Address:Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (NIIST), Pappanamcode, Trivandrum, Kerala, India.
[Ti] Title:Polyphenol rich ethanolic extract from Boerhavia diffusa L. mitigates angiotensin II induced cardiac hypertrophy and fibrosis in rats.
[So] Source:Biomed Pharmacother;87:427-436, 2017 Mar.
[Is] ISSN:1950-6007
[Cp] Country of publication:France
[La] Language:eng
[Ab] Abstract:Boerhavia diffusa is a renowned edible medicinal plant extensively used against different ailments including heart diseases in the traditional system of medicine in several countries. The present study aims to evaluate the therapeutic efficacy of ethanolic extract of Boerhavia diffusa (BDE) on cardiac hypertrophy and fibrosis induced by angiotensin II (Ang II) in male wistar rats and to identify the active components present in it. A substantial increase of hypertrophy markers such as cardiac mass index, concentration of ANP and BNP, cardiac injury markers like CK-MB, LDH and SGOT, has been observed in hypertrophied groups whereas BDE treatment attenuated these changes when compared to hypertrophied rats. Moreover, Ang II induced myocardial oxidative stress was reduced by BDE which was apparent from diminished level of lipid and protein oxidation products, increased activities of membrane bound ATPases and endogenous antioxidant enzymes along with enhanced translocation of Nrf2 from the cytosol to nucleus. It appears that BDE evokes its antioxidant effects by attenuating lipid peroxidation, enhancing the translocation of Nrf2 from the cytoplasm to nucleus as well as by regulating the metabolism of glutathione. The extent of fibrosis during cardiac hypertrophy was determined by histopathology analysis and the results revealed that BDE treatment considerably reduced the fibrosis in the heart. HPLC analysis of BDE leads to the identification of four compounds viz., quercetin, kaempferol, boeravinone B and caffeic acid. The study substantiate the effect of B. diffusa in protecting the heart from pathological hypertrophy and the attenuation of cardiac abnormalities may be partly attributed through the reduction of oxidative stress and cardiac fibrosis. Since the plant is widely used as a green leafy vegetable, incorporation of this plant in diet may be an alternative way for the prevention and better management of heart diseases and associated complications.
[Mh] MeSH terms primary: Angiotensin II/pharmacology
Cardiomegaly/chemically induced
Cardiomegaly/drug therapy
Fibrosis/chemically induced
Fibrosis/drug therapy
Nyctaginaceae/chemistry
Polyphenols/pharmacology
[Mh] MeSH terms secundary: Animals
Antioxidants/metabolism
Cardiomegaly/metabolism
Ethanol/chemistry
Fibrosis/metabolism
Glutathione/metabolism
Heart/drug effects
Lipid Peroxidation/drug effects
Male
Myocardium/metabolism
Oxidative Stress/drug effects
Plant Extracts/pharmacology
Plants, Medicinal/chemistry
Quercetin/pharmacology
Rats
Rats, Wistar
Reactive Oxygen Species/metabolism
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Antioxidants); 0 (Plant Extracts); 0 (Polyphenols); 0 (Reactive Oxygen Species); 11128-99-7 (Angiotensin II); 3K9958V90M (Ethanol); 9IKM0I5T1E (Quercetin); GAN16C9B8O (Glutathione)
[Em] Entry month:1702
[Cu] Class update date: 170224
[Lr] Last revision date:170224
[Js] Journal subset:IM
[Da] Date of entry for processing:170110
[St] Status:MEDLINE

  8 / 160 MEDLINE  
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[PMID]: 27918626
[Au] Autor:White PJ; Bowen HC; Broadley MR; El-Serehy HA; Neugebauer K; Taylor A; Thompson JA; Wright G
[Ad] Address:The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK.
[Ti] Title:Evolutionary origins of abnormally large shoot sodium accumulation in nonsaline environments within the Caryophyllales.
[So] Source:New Phytol;214(1):284-293, 2017 Apr.
[Is] ISSN:1469-8137
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The prevalence of sodium (Na)-'hyperaccumulator' species, which exhibit abnormally large shoot sodium concentrations ([Na] ) when grown in nonsaline environments, was investigated among angiosperms in general and within the Caryophyllales order in particular. Shoot Na concentrations were determined in 334 angiosperm species, representing 35 orders, grown hydroponically in a nonsaline solution. Many Caryophyllales species exhibited abnormally large [Na] when grown hydroponically in a nonsaline solution. The bimodal distribution of the log-normal [Na] of species within the Caryophyllales suggested at least two distinct [Na] phenotypes within this order. Mapping the trait of Na-hyperaccumulation onto the phylogenetic relationships between Caryophyllales families, and between subfamilies within the Amaranthaceae, suggested that the trait evolved several times within this order: in an ancestor of the Aizoaceae, but not the Phytolaccaceae or Nyctaginaceae, in ancestors of several lineages formerly classified as Chenopodiaceae, but not in the Amaranthaceae sensu stricto, and in ancestors of species within the Cactaceae, Portulacaceae, Plumbaginaceae, Tamaricaceae and Polygonaceae. In conclusion, a disproportionate number of Caryophyllales species behave as Na-hyperaccumulators, and multiple evolutionary origins of this trait can be identified within this order.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1612
[Cu] Class update date: 170426
[Lr] Last revision date:170426
[St] Status:In-Process
[do] DOI:10.1111/nph.14370

  9 / 160 MEDLINE  
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[PMID]: 27608964
[Au] Autor:Tupe RS; Kemse NG; Khaire AA; Shaikh SA
[Ad] Address:a Biochemical Sciences Division, Rajiv Gandhi Institute of IT and Biotechnology , Bharati Vidyapeeth University , Pune , Maharashtra , India.
[Ti] Title:Attenuation of glycation-induced multiple protein modifications by Indian antidiabetic plant extracts.
[So] Source:Pharm Biol;55(1):68-75, 2017 Dec.
[Is] ISSN:1744-5116
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:CONTEXT: Protein glycation is the major contributing factor in the development of diabetic complications. The antiglycation potential of medicinal plants provides a promising opportunity as complementary interventions for complications. OBJECTIVE: To investigate the antiglycation potential of 19 medicinal plants extracts using albumin by estimating different indicators: (1) glycation (early and late), (2) albumin oxidation, and (3) amyloid aggregation. MATERIALS AND METHODS: The effect of aqueous plant extracts (1% w/v) on protein glycation was assessed by incubating albumin (10 mg/mL) with fructose (250 mM) for 4 days. Degree of protein glycation in the absence and presence of plant extracts was assessed by estimating fructosamine, advanced glycation end products (AGEs), carbonyls, free thiol group and ß-amyloid aggregation. RESULTS: Petroselinum crispum, Boerhavia diffusa, Terminalia chebula, Swertia chirayita and Glycyrrhiza glabra showed significant antiglycating activity. P. crispum and A. barbadensis inhibited the carbonyl stress and protected the thiol group from oxidative damage. There was significant correlation between protein thiols and amyloid inhibition (R = -.69, p < .001). CONCLUSION: P. crispum, B. diffusa and T. chebula had the most potent antiglycation activity. These plant exerted noticeable antiglycation activity at different glycation modifications of albumin. These findings are important for identifying plants with potential to combat diabetic complications.
[Mh] MeSH terms primary: Amyloid beta-Peptides/metabolism
Glycation End Products, Advanced/metabolism
Hypoglycemic Agents/pharmacology
Nyctaginaceae/chemistry
Petroselinum/chemistry
Plant Extracts/pharmacology
Protein Processing, Post-Translational/drug effects
Serum Albumin, Bovine/metabolism
Terminalia/chemistry
[Mh] MeSH terms secundary: Fructosamine/metabolism
Fructose/metabolism
Glycosylation
Hypoglycemic Agents/isolation & purification
India
Oxidation-Reduction
Phytotherapy
Plant Extracts/isolation & purification
Plants, Medicinal
Protein Aggregation, Pathological
Protein Carbonylation/drug effects
Sulfhydryl Compounds/metabolism
Time Factors
[Pt] Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Name of substance:0 (Amyloid beta-Peptides); 0 (Glycation End Products, Advanced); 0 (Hypoglycemic Agents); 0 (Plant Extracts); 0 (Sulfhydryl Compounds); 0 (advanced glycation end products-bovine serum albumin); 27432CM55Q (Serum Albumin, Bovine); 30237-26-4 (Fructose); 4429-04-3 (Fructosamine)
[Em] Entry month:1703
[Cu] Class update date: 171116
[Lr] Last revision date:171116
[Js] Journal subset:IM
[Da] Date of entry for processing:160910
[St] Status:MEDLINE

  10 / 160 MEDLINE  
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[PMID]: 27667768
[Au] Autor:Karwasra R; Kalra P; Nag TC; Gupta YK; Singh S; Panwar A
[Ad] Address:Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
[Ti] Title:Safety assessment and attenuation of cisplatin induced nephrotoxicity by tuberous roots of Boerhaavia diffusa.
[So] Source:Regul Toxicol Pharmacol;81:341-352, 2016 Nov.
[Is] ISSN:1096-0295
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Cisplatin (Cis-diaminedichloroplatinum II) is a chemotherapeutic agent having well documented adverse effect as nephrotoxicity. This study was designed to evaluate the nephroprotective role of Boerhaavia diffusa in cisplatin-induced acute kidney injury. Wistar rats (n = 6) were allocated into six groups constituting normal control, cisplatin-induced, Boerhaavia diffusa root extract in doses 50, 100 and 200 mg/kg and Boerhaavia diffusa per se group, administered orally for a period of ten days. Intraperitoneal injection of cisplatin was administered on day 7, to all groups except normal control and Boerhaavia diffusa per se group. On day 10, cisplatin resulted in substantial nephrotoxicity in Wistar rats with significant (p < 0.001) elevation in serum creatinine and blood urea nitrogen, decline in the concentrations of reduced glutathione and superoxide dismutase, elevation in TNF-α level in renal tissues. Boerhaavia diffusa at a dose of 200 mg/kg body weight significantly (p < 0.001) ameliorates increased in serum creatinine, blood urea nitrogen, oxidative stress and inflammatory markers. In parallel to this, it also exhibits antiapoptotic activity through the reduction of active caspase-3 expression in kidneys. Findings indicate that Boerhaavia diffusa is effective in mitigating cisplatin-induced nephrotoxicity and thus, for this the acute and sub-acute toxicity studies conducted to evaluate the safety profile of Boerhaavia diffusa. The no-observed adverse effect level (NOAEL) of tuberous roots of Boerhaavia diffusa root extract was 1000 mg/kg.
[Mh] MeSH terms primary: Acute Kidney Injury/metabolism
Antineoplastic Agents/toxicity
Cisplatin/antagonists & inhibitors
Cisplatin/toxicity
Nyctaginaceae/chemistry
Plant Extracts/pharmacology
Plant Roots/chemistry
[Mh] MeSH terms secundary: Acute Kidney Injury/chemically induced
Acute Kidney Injury/pathology
Administration, Oral
Animals
Antineoplastic Agents/administration & dosage
Cisplatin/administration & dosage
Dose-Response Relationship, Drug
Drug-Related Side Effects and Adverse Reactions
Injections, Intraperitoneal
Male
Plant Extracts/administration & dosage
Plant Extracts/isolation & purification
Rats
Rats, Wistar
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Antineoplastic Agents); 0 (Plant Extracts); Q20Q21Q62J (Cisplatin)
[Em] Entry month:1707
[Cu] Class update date: 170704
[Lr] Last revision date:170704
[Js] Journal subset:IM
[Da] Date of entry for processing:160927
[St] Status:MEDLINE


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