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[PMID]: 29305677
[Au] Autor:de Vries LJ; Martirosyan M; van Domburg RT; Wijchers SA; Géczy T; Szili-Torok T
[Ad] Address:Department of Cardiology, Electrophysiology, Erasmus Medical Center, Rotterdam, The Netherlands.
[Ti] Title:Coupling interval variability of premature ventricular contractions in patients with different underlying pathology: an insight into the arrhythmia mechanism.
[So] Source:J Interv Card Electrophysiol;51(1):25-33, 2018 Jan.
[Is] ISSN:1572-8595
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:PURPOSE: Coupling interval (CI) variability of premature ventricular contractions (PVCs) is influenced by the underlying arrhythmia mechanism. The aim of this study was to compare CI variability of PVCs in different myocardial disease entities, in order to gain insight into their arrhythmia mechanism. METHODS: Sixty-four patients with four underlying pathologies were included: idiopathic (n = 16), non-ischemic dilated cardiomyopathy (NIDCM) (n = 16), familial cardiomyopathy (PLN/LMNA) (n = 16), and post-MI (n = 16)-associated PVCs. The post-MI group was included as a reference, on account of its known re-entry mechanism. On Holter registrations, the first 20 CIs of the dominant PVC morphology were measured manually after which median ΔCI and mean SD of CI/√R-R (= CI of PVC corrected for underlying heart rate) were obtained. Two observers independently measured PVC CIs on pre-selected Holter registrations in order to determine inter- and intra-observer reliability. RESULTS: The largest ΔCI was seen in the PLN/LMNA group (220 ms (120-295)), the lowest in the idiopathic group (120 ms (100-190)). The ΔCI in the PLN/LMNA group was significantly larger than the post-MI group (220 ms (120-295) vs 130 ms (105-155), p = 0.023). Mean SD of CI/√R-R in the PLN/LMNA group was also significantly higher than in the post-MI group (p = 0.044). Inter- and intra-observer reliability was good (ICC = 0.91 vs 0.86 and 0.96 vs 0.77, respectively). CONCLUSIONS: Low ΔCI and SD of CI/√R-R of idiopathic and NIDCM PVCs suggest that the underlying arrhythmia mechanisms might be re-entry or triggered activity. Abnormal automaticity or modulated parasystole are unlikely mechanisms. High CI variability in PLN/LMNA patients suggests that the re-entry and triggered activity are less likely mechanisms in this group.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[St] Status:In-Process
[do] DOI:10.1007/s10840-017-0309-8

  2 / 371 MEDLINE  
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[PMID]: 29263012
[Au] Autor:Gorla SR; Raja KR; Sokoloski MC; Swaminathan S
[Ad] Address:Division of Pediatric Cardiology, Department of Pediatrics, Jackson Memorial Hospital, University of Miami/Miller School of Medicine, Miami, Florida, United States.
[Ti] Title:Sinus node dysfunction masquerading as complete atrioventricular block in the setting of atrial parasystole after heart transplantation.
[So] Source:J Electrocardiol;, 2017 Dec 07.
[Is] ISSN:1532-8430
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Heart transplantation is the gold standard for treatment of end stage heart failure. Atrial parasystole (AP), defined as the presence of an additional dissociated atrial pacemaker on a surface electrocardiogram, has been described to be seen after heart transplantation using biatrial surgical technique. AP may pose a challenge in diagnosing underlying rhythm disturbances in these patients. Here, we report a rare phenomenon of junctional escape rhythm with sinus node dysfunction, mimicking as complete atrioventricular block due to the presence of an AP, in a heart transplant recipient.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171221
[Lr] Last revision date:171221
[St] Status:Publisher

  3 / 371 MEDLINE  
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[PMID]: 27868219
[Au] Autor:Yadlapati A; Kim SS; Knight BP
[Ad] Address:Division of Cardiology, Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
[Ti] Title:New Heart…New Rhythm.
[So] Source:Pacing Clin Electrophysiol;40(1):67-68, 2017 Jan.
[Is] ISSN:1540-8159
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Atrial Premature Complexes/diagnosis
Atrial Premature Complexes/etiology
Graft Rejection/etiology
Heart Block/diagnosis
Heart Block/etiology
Heart Transplantation/adverse effects
[Mh] MeSH terms secundary: Adult
Diagnosis, Differential
Electrocardiography/methods
Female
Graft Rejection/diagnosis
Heart Failure/complications
Heart Failure/therapy
Humans
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1703
[Cu] Class update date: 170817
[Lr] Last revision date:170817
[Js] Journal subset:IM
[Da] Date of entry for processing:161122
[St] Status:MEDLINE
[do] DOI:10.1111/pace.12980

  4 / 371 MEDLINE  
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[PMID]: 28304253
[Au] Autor:Collins DE; Dozier BL; Stanton JJ; Colgin LM; MacAllister R
[Ad] Address:Center for Comparative Medicine, Baylor College of Medicine, Houston, Texas;, Email: dcollins@bcm.edu.
[Ti] Title:Ventricular Parasystole in a Neonatal Rhesus Macaque ( ).
[So] Source:Comp Med;66(6):489-493, 2016 Dec 01.
[Is] ISSN:1532-0820
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A 6-d-old Indian-origin female rhesus macaque (Macaca mulatta) presented with bradycardia shortly after sedation with ketamine. No other cardiac abnormalities were apparent. Approximately 2 wk after the initial presentation, the macaque was again bradycardic and exhibited a regularly irregular arrhythmia on a prestudy examination. ECG, echocardiography, blood pressure measurement, SpO2 assessment, and a CBC analysis were performed. The echocardiogram and bloodwork were normal, but the infant was hypotensive at the time of echocardiogram. The ECG revealed ventricular parasystole. Ventricular parasystole is considered a benign arrhythmia caused by an ectopic pacemaker that is insulated from impulses from the sinus node. Given this abnormality, the macaque was transferred to a short-term study protocol, according to veterinary recommendation. On the final veterinary exam, a grade 3 systolic murmur and a decrease in arrhythmia frequency were noted. Gross cardiac lesions were not identified at necropsy the following day. Cardiac tissue sections were essentially normal on microscopic examination. This infant did not display signs of cardiovascular insufficiency, and a review of the medical record indicated normal growth, feed intake and activity levels. This case demonstrates the importance of appropriate screening of potential neonatal and juvenile research candidates for occult cardiovascular abnormalities. Whether the arrhythmia diagnosed in this case was truly innocuous is unclear, given the documented hypotension and the development of a systolic heart murmur.
[Mh] MeSH terms primary: Heart Ventricles/pathology
Macaca mulatta
Parasystole/veterinary
[Mh] MeSH terms secundary: Animals
Animals, Laboratory
Bradycardia/veterinary
Echocardiography/veterinary
Female
Heart Ventricles/abnormalities
Heart Ventricles/diagnostic imaging
Humans
Monkey Diseases/pathology
Parasystole/pathology
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171013
[Lr] Last revision date:171013
[Js] Journal subset:IM
[Da] Date of entry for processing:170318
[St] Status:MEDLINE

  5 / 371 MEDLINE  
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[PMID]: 27014081
[Au] Autor:Wdowczyk J; Makowiec D; Dorniak K; Gruchala M
[Ad] Address:1st Chair and Clinic of Cardiology, Medical University of Gdansk Gdansk, Poland.
[Ti] Title:Visualization of Heart Rate Variability of Long-Term Heart Transplant Patient by Transition Networks: A Case Report.
[So] Source:Front Physiol;7:79, 2016.
[Is] ISSN:1664-042X
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:We present a heart transplant patient at his 17th year of uncomplicated follow-up. Within a frame of routine check out several tests were performed. With such a long and uneventful follow-up some degree of graft reinnervation could be anticipated. However, the patient's electrocardiogram and exercise parameters seemed largely inconclusive in this regard. The exercise heart rate dynamics were suggestive of only mild, if any parasympathetic reinnervation of the graft with persisting sympathetic activation. On the other hand, traditional heart rate variability (HRV) indices were inadequately high, due to erratic rhythm resulting from interference of the persisting recipient sinus node or non-conducted atrial parasystole. New tools, originated from network representation of time series, by visualization short-term dynamical patterns, provided a method to discern HRV increase due to reinnervation from other reasons.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1603
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:160326
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3389/fphys.2016.00079

  6 / 371 MEDLINE  
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[PMID]: 25057225
[Au] Autor:Ramasamy C; Kumar S; Selvaraj RJ
[Ad] Address:Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
[Ti] Title:Parasystole in a mahaim accessory pathway.
[So] Source:Indian Pacing Electrophysiol J;14(4):223-6, 2014 Jul.
[Is] ISSN:0972-6292
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Automaticity has been described in Mahaim pathways, both spontaneously and during radiofrequency ablation. We describe an unusual case of automatic rhythm from a Mahaim pathway presenting as parasystole. The parasystolic beats were also found to initiate tachycardia, resulting in initial presentation with incessant tachycardia and tachycardia induced cardiomyopathy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:140725
[St] Status:PubMed-not-MEDLINE

  7 / 371 MEDLINE  
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[PMID]: 25057223
[Au] Autor:Tekkatte R; Hamoud A; Warren C; Barry J
[Ad] Address:Cardiff and Vale University Health Board, United Kingdom.
[Ti] Title:Parasystole in a mahaim accessory pathway.
[So] Source:Indian Pacing Electrophysiol J;14(4):211-6, 2014 Jul.
[Is] ISSN:0972-6292
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Hypertrophic cardiomyopathy's (HCM) association with sudden cardiac death is well recognised. The risk of sudden cardiac death is known to increase when there is a history of unexplained syncope, abnormal blood pressure response during exercise, severe left ventricular hypertrophy or a family history of unexplained death. Implantable Cardioverter Defibrillator (ICD) implantation has been widely used for primary and secondary prevention of sudden cardiac death (SCD) in people with HCM. Subcutaneous ICD (S-ICD) therapy has been developed to overcome some of the problems associated with the transvenous leads used in conventional ICDs. In this article, we report the use of S-ICD in a patient with HCM and multiple risk factors for sudden cardiac death, this device had to be extracted due to recurrent inappropriate shocks caused by over sensing of atrial flutter and failure to treat a VT episode. We are not aware of any reports of inappropriate shocks caused by atrial flutter in people with a S-ICD.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1407
[Cu] Class update date: 170220
[Lr] Last revision date:170220
[Da] Date of entry for processing:140725
[St] Status:PubMed-not-MEDLINE

  8 / 371 MEDLINE  
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[PMID]: 24786866
[Au] Autor:Kenia AS; Ho RT; Pavri BB
[Ad] Address:Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
[Ti] Title:Narrowing with prematurity-what is the mechanism?
[So] Source:Pacing Clin Electrophysiol;37(10):1404-7, 2014 Oct.
[Is] ISSN:1540-8159
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Cardiac Complexes, Premature/physiopathology
Electrocardiography
[Mh] MeSH terms secundary: Aged, 80 and over
Female
Humans
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1511
[Cu] Class update date: 141002
[Lr] Last revision date:141002
[Js] Journal subset:IM
[Da] Date of entry for processing:140503
[St] Status:MEDLINE
[do] DOI:10.1111/pace.12413

  9 / 371 MEDLINE  
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[PMID]: 24497516
[Au] Autor:Vaidya VR; Cha YM; Asirvatham SJ; Pellikka PA; Pislaru SV
[Ad] Address:Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
[Ti] Title:To shock or not to shock? Parasystole of the left atrial appendage mimicking sinus rhythm at TEE-guided cardioversion.
[So] Source:Eur Heart J Cardiovasc Imaging;15(7):833, 2014 Jul.
[Is] ISSN:2047-2412
[Cp] Country of publication:England
[La] Language:eng
[Mh] MeSH terms primary: Arrhythmia, Sinus/diagnosis
Atrial Appendage/diagnostic imaging
Catheter Ablation/adverse effects
Echocardiography, Transesophageal/methods
Electric Countershock/methods
Parasystole/diagnosis
[Mh] MeSH terms secundary: Atrial Appendage/physiopathology
Atrial Fibrillation/diagnosis
Atrial Fibrillation/surgery
Catheter Ablation/methods
Diagnosis, Differential
Echocardiography, Doppler, Pulsed/methods
Electrocardiography/methods
Follow-Up Studies
Humans
Male
Middle Aged
Parasystole/therapy
Recurrence
Risk Assessment
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1503
[Cu] Class update date: 161125
[Lr] Last revision date:161125
[Js] Journal subset:IM
[Da] Date of entry for processing:140206
[St] Status:MEDLINE
[do] DOI:10.1093/ehjci/jeu012

  10 / 371 MEDLINE  
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[PMID]: 24360315
[Au] Autor:Thiara R; Nacca N; Szombathy T
[Ad] Address:Department of Emergency Medicine, SUNY Upstate Medical University, St Syracuse, NY 13202, USA. Electronic address: thiarar@upstate.edu.
[Ti] Title:Are those premature ventricular complexes?!
[So] Source:Am J Emerg Med;32(4):396.e1-2, 2014 Apr.
[Is] ISSN:1532-8171
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Ventricular parasystole has been known to be a benign rhythm. We present a case of a 53-year-old man with chest pain and ventricular parasystole on electrocardiogram upon initial presentation. He was admitted and found to have normal serial cardiac enzymes and nuclear stress testing. He was discharged home with primary care follow-up. We highlight this case, as ventricular parasystole has been shown to be associated with cardiovascular disease and is a rhythm that should not be ignored. Our review of the literature shows that a thorough cardiovascular investigation should take place when this rhythm is identified.
[Mh] MeSH terms primary: Ventricular Premature Complexes/diagnosis
[Mh] MeSH terms secundary: Diagnosis, Differential
Diagnostic Imaging
Electrocardiography
Humans
Male
Middle Aged
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1406
[Cu] Class update date: 140401
[Lr] Last revision date:140401
[Js] Journal subset:IM
[Da] Date of entry for processing:131224
[St] Status:MEDLINE


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