Database : MEDLINE
Search on : Passiflora [Words]
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[PMID]: 29513962
[Au] Autor:Hadas E; Ozarowski M; Derda M; Thiem B; Cholewinski M; Skrzypczak L; Gryszczynska A; Piasecka A
[Ti] Title:THE USE OF EXTRACTS FROM PASSIFLORA SPP. IN HELPING THE TREATMENT OF ACANTHAMOEBIASIS.
[So] Source:Acta Pol Pharm;74(3):921-928, 2017 May.
[Is] ISSN:0001-6837
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Chronic progressive diseases of the central nervous system such as granulomatous amoebic encephalitis, amoebic keratitis, amoebic pneumonitis and also skin infections caused by free-living amoebae (Acanhamoeba spp.) are a significant challenge for pharmacotherapy. This is due to the lack of effective treatment because of encystation, which makes the amoebae highly resistant to anti-amoebic drugs. A very inter- esting and promising source of future drugs in this area are plant materials obtained not only from the habitat but also from plant in vitro culture as an alternative source of biomaterials. Alcoholic extracts from leaves of Passiflora incarnata, P. caerulea, P. alata (Passifloraceae) and from callus cultures were evaluated in vito for amoebicidal activity. Phytochemical analysis showed that all extracts contained phenolic compounds including flavonoids? Biological study revealed that all extracts showed amoebostatic and amoebicidal properties in concentrations from 4 to 12 mg/mL. Extracts of P. alata leaf and callus showed the most effective activities (IC5, 4.01 mg/mL, IC,5 7.29 mg/mL, respectively) after 48 h of exposure, which was correlated with the highest concentration of total phenolics and flavonoids in comparison with other extracts.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process

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[PMID]: 29463053
[Au] Autor:Song Y; Wei XQ; Li MY; Duan XW; Sun YM; Yang RL; Su XD; Huang RM; Wang H
[Ad] Address:Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China. songya_1990@163.com.
[Ti] Title:Nutritional Composition and Antioxidant Properties of the Fruits of a Chinese Wild Passiflora foetida.
[So] Source:Molecules;23(2), 2018 Feb 19.
[Is] ISSN:1420-3049
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:The aim of this work was to evaluate the main nutrients and their antioxidant properties of a Chinese wild edible fruit, , collected from the ecoregion of Hainan province, China. The analytical results revealed that fruits were rich in amino acids (1097 mg/100 g in total), minerals (595.75 mg/100 g in total), and unsaturated fatty acids (74.18 g/100 g in total fat). The lyophilized powder of edible portion contained the higher polyphenols content than the inedible portion powder. The UPLC-Q-TOF-MS analysis of the extractable and non-extractable phenolics indicated the presence of 65 compounds including 39 free phenolics, 14 insoluble-glycoside-phenolics, and 22 insoluble-ester-phenolics. In addition, the non-extractable phenolics obtained by alkali hydrolysis showed significant antioxidant activities by/through DPPH and ABTS radical scavenging. These findings of fruits, for the first time, suggest that these polyphenol-rich fruits may have potential nutraceutical efficacies.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180221
[Lr] Last revision date:180221
[St] Status:In-Process

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[PMID]: 29458926
[Au] Autor:Ozturk Z; Kalayci CC
[Ad] Address:Department of Clinical Pharmacology and Toxicology, Izmir Ataturk Research Hospital, Izmir, Turkey. Electronic address: dr.zeyneb@hotmail.com.
[Ti] Title:Pregnancy outcomes in psychiatric patients treated with passiflora incarnata.
[So] Source:Complement Ther Med;36:30-32, 2018 Feb.
[Is] ISSN:1873-6963
[Cp] Country of publication:Scotland
[La] Language:eng
[Ab] Abstract:Passiflora incarnata is marketed in many countries as anxiolytic herbal supplement. Herbal medicines are natural products, but it doesn't mean they are always safe, especially during pregnancy. Passiflora incarnata extract was not teratogenic in experimental studies. However, there are no data available on possible effects on human pregnancy. Here we report five pregnant women with depression and/or anxiety who used passiflora incarnata in pregnancy. We observed one pregnancy resulting in neonatal death, two pregnancies with premature rupture of membranes, two infants with meconium aspiration syndrome and one infant with persistent pulmonary hypertension. No birth defects and no growth or developmental abnormalities for the live born infants were reported at 6 months of age. This observation is important since there have been no human reports about the use of passiflora incarnata in pregnant women. Pregnant women exposed to passiflora incarnata should be monitored, unless further data are available.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[St] Status:In-Process

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[PMID]: 29454287
[Au] Autor:Gazola AC; Costa GM; Zucolotto SM; Castellanos L; Ramos FA; de Lima TCM; Schenkel EP
[Ad] Address:Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina, Florianópolis, 88040-970, Brazil; Departamento de Farmácia, Centro Universitário Barriga Verde, Orleans, 88870-000 Brazil. Electronic address: andressa@unibave.net.
[Ti] Title:The sedative activity of flavonoids from Passiflora quadrangularis is mediated through the GABAergic pathway.
[So] Source:Biomed Pharmacother;100:388-393, 2018 Feb 14.
[Is] ISSN:1950-6007
[Cp] Country of publication:France
[La] Language:eng
[Ab] Abstract:The aim of this study was to investigate the sedative activity of the aqueous leaf extract of Passiflora quadrangularis, a species that is widely cultivated and consumed in South America, and to identify its main constituents and elucidate the involvement of the GABAergic pathway in its mechanism of action. The bioguided fractionation of the crude extract showed a positive relationship between the sedative activity of the extract and its flavonoids. The methods employed to identify and isolate its main flavonoids resulted in the identification of vitexin-2''-O-xyloside, vitexin-2''-O-glucoside, orientin-2''-O-xyloside and orientin-2''-O-glucoside. Vitexin-2"-O-xyloside, the major flavonoid of the extract, showed sedative activity after oral administration in mice.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180217
[Lr] Last revision date:180217
[St] Status:Publisher

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[PMID]: 29433687
[Au] Autor:Meier S; Haschke M; Zahner C; Kruttschnitt E; Drewe J; Liakoni E; Hammann F; Gaab J
[Ad] Address:Division of Clinical Psychology and Psychotherapy, Faculty of Psychology, University of Basel, Missionsstrasse 62, 4055 Basel, Switzerland. Electronic address: sibylle.meier@unibas.ch.
[Ti] Title:Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men - An explorative randomized placebo-controlled double-blind study.
[So] Source:Phytomedicine;39:85-92, 2018 Jan 15.
[Is] ISSN:1618-095X
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:BACKGROUND: Considering the negative effects of stress on health, there is a growing interest in stress-reducing interventions. The present study examines the effects of a fixed combination of valerian, passion flower, lemon balm, and butterbur extracts (Ze 185) on biological and affective responses to a standardized psychosocial stress paradigm. PURPOSE: The aim of the present study was to investigate the efficacy of Ze 185 on cortisol and anxiety stress responses to acute psychosocial stress in healthy subjects. STUDY DESIGN: This study was a randomized, placebo-controlled, double blind study with 3 parallel groups. METHODS: 72 healthy male participants were randomized to 3 groups (Ze 185, placebo or no treatment) during 4 days prior to a standardized psychosocial stress paradigm. Principle outcomes were salivary cortisol and self-reported anxiety responses to stress assessed at the fourth day. RESULTS: The stress paradigm induced significant and large cortisol and self-reported anxiety responses. Groups did not differ significantly in their salivary cortisol response to stress, but participants in the Ze 185 condition showed significantly attenuated responses in self-reported anxiety in comparison to placebo (F(3, 41) = 3.33, p = 0.03) and no treatment (F(3, 43) = 2.77, p = 0.05). CONCLUSION: The results show that Ze 185 significantly attenuated the subjective emotional stress response during an acute stress situation, without affecting biological stress responses. Given that a circumscribed biological stress response is to be considered as an adaptive mechanism, Ze 185 reduces self-reported anxiety response to stress without affecting assumingly adaptive biological stress responses.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[St] Status:In-Process

  6 / 577 MEDLINE  
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[PMID]: 29432576
[Au] Autor:Tominaga J; Shimada H; Kawamitsu Y
[Ad] Address:Faculty of Agriculture, University of the Ryukyus, Okinawa Japan.
[Ti] Title:Direct Measurement Solves Overestimation of Intercellular CO2 Concentration in Leaf Gas-Exchange Measurements.
[So] Source:J Exp Bot;, 2018 Feb 08.
[Is] ISSN:1460-2431
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Intercellular CO2 concentration of leaves (ci) is a critical parameter in photosynthesis. Nevertheless, uncertainties in calculating ci (ci(c)) arise as stomata close. Here, applying a system for directly measuring ci (ci(m)) to a commercial gas-exchange equipment, we demonstrate overestimation of ci(c) without stimulating stomatal closure. Gas-exchange was measured on one leaf side while ci(m) was acquired simultaneously on the other side in hypostomatous passionfruit (Passiflora edulis Sims), and amphistomatous sunflower (Helianthus annuus L.) and common bean (Phaseolus vulgaris L.). The adaxial surface showed comparable ci(c) and ci(m) in the sunflower, whereas that having low stomatal density in the common bean showed the ci(c) markedly differed from the ci(m) despite keeping the stomata open. However, the latter discrepancy disappeared when measuring the leaf flipped upside down so that the gas-exchange was measured (i.e., ci was calculated) on the abaxial side having much higher stomatal density. Together, the passionfruit showed the largest discrepancy on the astomatous side, concluding that cuticle has large impacts on the calculation. The direct measurement is recommended for the better option than the calculation when stomatal gas transport is restricted. Occurrence of the overestimation as well as prospects of the direct measurement are discussed.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180212
[Lr] Last revision date:180212
[St] Status:Publisher
[do] DOI:10.1093/jxb/ery044

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[PMID]: 29340606
[Au] Autor:Zhang FP; Sussmilch F; Nichols DS; Cardoso AA; Brodribb TJ; McAdam SAM
[Ad] Address:Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, China.
[Ti] Title:Leaves, not roots or floral tissue, are the main site of rapid, external pressure-induced ABA biosynthesis in angiosperms.
[So] Source:J Exp Bot;, 2018 Jan 11.
[Is] ISSN:1460-2431
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Rapid biosynthesis of abscisic acid (ABA) in the leaf, triggered by a decrease in cell volume, is essential for a functional stomatal response to vapour pressure deficit (VPD) in angiosperms. However, it is not known whether rapid biosynthesis of ABA is triggered in other plant tissues as well. Through the application of external pressure to flower, root and leaf tissues, we test whether a reduction in cell volume can trigger rapid increases in ABA levels across plant body in two species Solanum lycopersicum and Passiflora tarminiana. Our results show that, in contrast to rapid ABA synthesis in the leaf, flower and root tissue did not show a significant, rapid increase in ABA level in response to a drop in cell volume over a short time-frame, suggesting that fast ABA biosynthesis occurs only in leaf, not in flower or root tissues. A gene encoding the key, rate-limiting carotenoid cleavage enzyme (9`-cis-epoxycarotenoid dioxygenase, NCED) in ABA biosynthetic pathway in S. lycopersicum, NCED1, was unregulated to lesser degree in flowers and roots compared to leaves in response to applied pressure. In both species, floral tissues contained substantially lower levels of NCED substrate 9`-cis-neoxanthin than leaves, and this ABA precursor could not be detected in roots. Slow and minimal ABA biosynthesis was detected after 2 h in petals, indicating that floral tissue is capable of synthesising ABA in response to sustained water deficit. Our results indicate that rapid ABA biosynthesis predominantly occurs in the leaves, and not in other tissues.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180117
[Lr] Last revision date:180117
[St] Status:Publisher
[do] DOI:10.1093/jxb/erx480

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[PMID]: 28556245
[Au] Autor:Coelho EM; de Azevêdo LC; Viana AC; Ramos IG; Gomes RG; Lima MDS; Umsza-Guez MA
[Ad] Address:Department of Food Technology, Federal Institute of Sertão Pernambucano, Petrolina, Pernambuco, Brazil.
[Ti] Title:Physico-chemical properties, rheology and degree of esterification of passion fruit (Passiflora edulis f. flavicarpa) peel flour.
[So] Source:J Sci Food Agric;98(1):166-173, 2018 Jan.
[Is] ISSN:1097-0010
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: The peel of yellow passion fruit is as an agro-industrial waste of great environmental impact, representing more than 50% of the total weight of the fruit. For this reason, and also considering its importance as a source of functional components such as pectin, this organic waste is increasingly attracting the attention of researchers. The aim of this study was to investigate the physico-chemical composition and physical properties of this material, which may be of interest to the food industry. RESULTS: We obtained two samples of passion fruit peel flour applying different processes: flour without treatment (FWOT) and flour with treatment by maceration (FWT). It was found that the flour samples contain, respectively, 372.4 g kg and 246.7 kg of soluble fiber and, according to the FTIR analysis, this material corresponds to high and low methoxyl pectins, respectively. CONCLUSION: The flour obtained by maceration (FWT) offers greater benefits for industrial use, with 60% fewer tannins and greater thermal stability. In addition, this sample does not reabsorb moisture as easily, although FWOT also shows potential for use in dietary products. Considering the pseudoplastic properties of the flours, the application of both samples could be expanded to many industrial sectors. © 2017 Society of Chemical Industry.
[Mh] MeSH terms primary: Flour/analysis
Fruit/chemistry
Passiflora/chemistry
[Mh] MeSH terms secundary: Dietary Fiber/analysis
Esterification
Pectins/analysis
Rheology
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dietary Fiber); 0 (Pectins); 89NA02M4RX (pectin)
[Em] Entry month:1801
[Cu] Class update date: 180102
[Lr] Last revision date:180102
[Js] Journal subset:IM
[Da] Date of entry for processing:170531
[St] Status:MEDLINE
[do] DOI:10.1002/jsfa.8451

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[PMID]: 29260908
[Au] Autor:Rathnayake GRN; Kumar NS; Jayasinghe L; Araya H; Fujimoto Y
[Ad] Address:a National Institute of Fundamental Studies , Kandy , Sri Lanka.
[Ti] Title:Chemical investigation of metabolites produced by an endophytic fungi Phialemonium curvatum from the leaves of Passiflora edulis.
[So] Source:Nat Prod Res;:1-4, 2017 Dec 20.
[Is] ISSN:1478-6427
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Phialemonium curvatum, an endophytic fungus isolated from the leaves of Passiflora edulis was cultured in potato dextrose broth (PDB) media and chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of 4-hydroxybenzoic acid (1), 3-indole acetic acid (2), solaniol (3), uracil (4), uridine (5) and glycerol (6). Compound 2 showed a weak antifungal activity against Cladosporium cladosporioides. This is the first report of the isolation of the endophytic fungus P. curvatum from P. edulis and complete CNMR assignments of 3.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171220
[Lr] Last revision date:171220
[St] Status:Publisher
[do] DOI:10.1080/14786419.2017.1416373

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[PMID]: 29199463
[Au] Autor:Hu Y; Jiao L; Jiang MH; Yin S; Dong P; Zhao ZM; Yang DP; Ho PT; Wang DM
[Ad] Address:a School of Pharmaceutical Sciences , Sun Yat-Sen University , Guangzhou , P. R. China.
[Ti] Title:A new C-glycosyl flavone and a new neolignan glycoside from Passiflora edulis Sims peel.
[So] Source:Nat Prod Res;:1-7, 2017 Dec 04.
[Is] ISSN:1478-6427
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:A new C-glycosyl flavone, Chrysin-8-C-(2″-O-ß-6-deoxy-glucopyranosyl)-ß-D-glucopyranoside (1), a new neolignan glycoside, citrusin G (2), as well as 15 known compounds (3-17) were isolated from the peel of Passiflora edulis Sims. The structure determinations were primarily based on comprehensive spectroscopic analyses, and the absolute configuration of 2 were unequivocally determined by the CD experiment and chemical transformation. Compound 1 represents the rare examples of the flavonoid featuring a deoxy glucose sugar moiety. Compounds 5, 7 and 9 exhibited moderate inhibitory effects on nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells, with IC values of 34.92, 16.12 and 26.67 µM, respectively.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171204
[Lr] Last revision date:171204
[St] Status:Publisher
[do] DOI:10.1080/14786419.2017.1410809


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