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[PMID]: 27288851
[Au] Autor:Layne EA; DeBoer DJ
[Ad] Address:Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI, 53706, USA. Electronic address: elayne@vetmed.wisc.edu.
[Ti] Title:Serum Malassezia-specific IgE in dogs with recurrent Malassezia otitis externa without concurrent skin disease.
[So] Source:Vet Immunol Immunopathol;176:1-4, 2016 Aug.
[Is] ISSN:1873-2534
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Immediate-type hypersensitivity (ITH), mediated by IgE, to Malassezia pachydermatis is recognized in atopic dogs with recurrent yeast dermatitis and otitis externa (OE). Malassezia-associated OE commonly occurs in dogs without other signs of atopic dermatitis (AD). The aim of this study was to detect Malassezia-specific IgE in the sera of dogs with recurrent Malassezia OE without concurrent skin disease. Sera from healthy dogs were used for comparison. An FcεRIα-based ELISA was used to measure Malassezia-specific IgE. There was no significant difference between number of positive affected dogs (6/21, 29%) and number of positive unaffected dogs (15/86, 17%) (P=0.36). There was also no significant difference in the concentrations of Malassezia-specific IgE between the two groups (P=0.97). Malassezia-specific IgE did not distinguish between patient groups so, as with other canine allergens, serum IgE reactivity for Malassezia could not be used to differentiate between diseased and healthy patients. The presence of Malassezia-specific IgE in some of the affected dogs might indicate ITH to Malassezia in those dogs. Evaluation of ITH via intradermal test reactivity and response to allergen-specific immunotherapy might clarify the role of Malassezia-associated ITH in similarly affected dogs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 27155491
[Au] Autor:Corace KM; Srigley JA; Hargadon DP; Yu D; MacDonald TK; Fabrigar LR; Garber GE
[Ad] Address:University of Ottawa, Ottawa K1N 6N5, Canada; University of Ottawa Institute of Mental Health Research, Ottawa K1Z 7K4, Canada; Ottawa Hospital Research Institute, Ottawa K1Y 4E9, Canada. Electronic address: kim.corace@theroyal.ca....
[Ti] Title:Using behavior change frameworks to improve healthcare worker influenza vaccination rates: A systematic review.
[So] Source:Vaccine;34(28):3235-42, 2016 Jun 14.
[Is] ISSN:1873-2518
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Influenza vaccination of healthcare workers (HCW) is important for protecting staff and patients, yet vaccine coverage among HCW remains below recommended targets. Psychological theories of behavior change may help guide interventions to improve vaccine uptake. Our objectives were to: (1) review the effectiveness of interventions based on psychological theories of behavior change to improve HCW influenza vaccination rates, and (2) determine which psychological theories have been used to predict HCW influenza vaccination uptake. METHODS: MEDLINE, EMBASE, CINAHL, PsycINFO, The Joanna Briggs Institute, SocINDEX, and Cochrane Database of Systematic Reviews were searched for studies that applied psychological theories of behavior change to improve and/or predict influenza vaccination uptake among HCW. RESULTS: The literature search yielded a total of 1810 publications; 10 articles met eligibility criteria. All studies used behavior change theories to predict HCW vaccination behavior; none evaluated interventions based on these theories. The Health Belief Model was the most frequently employed theory to predict influenza vaccination uptake among HCW. The remaining predictive studies employed the Theory of Planned Behavior, the Risk Perception Attitude, and the Triandis Model of Interpersonal Behavior. The behavior change framework constructs were successful in differentiating between vaccinated and non-vaccinated HCW. Key constructs identified included: attitudes regarding the efficacy and safety of influenza vaccination, perceptions of risk and benefit to self and others, self-efficacy, cues to action, and social-professional norms. The behavior change frameworks, along with sociodemographic variables, successfully predicted 85-95% of HCW influenza vaccination uptake. CONCLUSION: Vaccination is a complex behavior. Our results suggest that psychological theories of behavior change are promising tools to increase HCW influenza vaccination uptake. Future studies are needed to develop and evaluate novel interventions based on behavior change theories, which may help achieve recommended HCW vaccination targets.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

  3 / 4445861 MEDLINE  
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[PMID]: 26826911
[Au] Autor:Ben Amor I; Rekik T; Louati N; Lahiani W; Rekik H; Peyrard T; Menif H; Gargouri J
[Ad] Address:CRTS de Sfax, 99/UR/08-33, université de Sfax, Sfax, Tunisie. Electronic address: ikbeam@yahoo.fr....
[Ti] Title:Difficultés de la prise en charge de l'allo-immunisation anti-public. [Difficulties of the care of public antigen alloimmunization].
[So] Source:Transfus Clin Biol;23(2):103-5, 2016 May.
[Is] ISSN:1953-8022
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:Alloimmunization against high-frequency erythrocyte antigens is a problematic situation in terms of laboratory diagnosis, transfusion and obstetrical management. We report the case of a pregnant woman alloimmunized against public Ag. We detail the difficulties of alloantibody (Ab) identification and transfusion management of the deliveries. A 29-year-old pregnant woman was hospitalized in gynecology and obstetrics departments at 36 weeks of gestation for assessment of hydrops fetalis. Antibody identification test revealed the presence of a pan-reactive antibody. Investigations realized in CNRGS (Paris) concluded in anti-GE2+anti-RH3+autoantibody. The red cell phenotype was GE: -2,3. A therapeutic interruption of the pregnancy was indicated. A program of autologous transfusion was organized with withdrawal of 2 units of blood. The 2nd pregnancy took place normally. Before delivery, an autologous blood reserve consisting of 2 red cell packs and 2 fresh frozen plasma was withdrawn and transfused after delivery. The management of anti-public alloimmunization poses several problems. The first one is of diagnostic nature with, on the one hand, the difficulty of Ab identification by the available red cell panels and, on the other hand, the possible presence of alloantibodies of transfusional or obstetric interest masked by anti-public Ab. The second is represented by transfusional care of these patients. In the absence of a national reserve of frozen rare blood, the autologous transfusion remains the only alternative. However, it can answer only a limited number of indications and only in case of moderate blood loss.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 26796677
[Au] Autor:Brick C; Atouf O; Essakalli M
[Ad] Address:Unité d'immunologie, service de transfusion sanguine et d'hémovigilance, hôpital des Enfants de Rabat, CHU Ibn Sina, 10000 Rabat, Maroc. Electronic address: brickchehrazade@yahoo.fr.
[Ti] Title:Suivi immunologique en transplantation rénale : 13 ans d'expérience d'un laboratoire d'histocompatibilité marocain. [Immunological monitoring in kidney transplantation: 13 years experience of a Moroccan histocompatibility laboratory].
[So] Source:Transfus Clin Biol;23(2):86-94, 2016 May.
[Is] ISSN:1953-8022
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:PURPOSE OF STUDY: The quality of the immunological monitoring is crucial because it determines the success of the kidney transplantation. The scope of this work is to describe the experience of the department of immunological unity of the Ibn Sina university hospital in Rabat regarding the immunological monitoring of patients transplanted between 2001 and 2014. PATIENTS AND METHODS: Patient samples were collected from nephrology services of different public and private hospitals of Morocco. The tests conducted in the context of immunological monitoring are ABO typing, HLA-A, B, DR, DQ typing, anti-HLA antibodies detection and identification and cross-match. RESULTS: One hundred and fourteen benefited from a pre- and post-transplant immunological monitoring in our laboratory. The percentage of recipients having between 2 and 5 stored sera is 60.5 before transplantation and 56.1 after transplantation. Immunized patients account for 22.8% before the transplant and 17.6% after transplantation. Ninety-seven patients still have a functional graft, while 4 of them had DSA of low intensity before transplantation. Five immunological rejections were reported while the cross-match were negative and no DSA was identified before transplantation. Patient survival and graft at 1 year was 98.2% and 92.7% respectively. CONCLUSION: Conducting regular immunological monitoring is sometimes difficult in our context, however, the results are satisfactory in terms of graft and patients survival.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

  5 / 4445861 MEDLINE  
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[PMID]: 26791918
[Au] Autor:Ankouane F; Noah Noah D; Atangana MM; Kamgaing Simo R; Guekam PR; Biwolé Sida M
[Ad] Address:Faculté de médecine et des sciences biomédicales, université de Yaoundé 1, centre hospitalier et universitaire de Yaoundé, Yaoundé, Cameroun. Electronic address: ankouaneandoulo@yahoo.com....
[Ti] Title:Séroprévalence des virus des hépatites B et C, du VIH-1/2 et de la syphilis chez les donneurs de sang de l'hôpital central de Yaoundé, région du centre, Cameroun. [Seroprevalence of hepatitis B and C viruses, HIV-1/2 and syphilis among blood donors in the Yaoundé Central Hospital in the centre region of Cameroon].
[So] Source:Transfus Clin Biol;23(2):72-7, 2016 May.
[Is] ISSN:1953-8022
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:OBJECTIVES: Prevention of blood transfusion-transmitted infections includes blood donor screening and effective infectious markers screening for donated blood. This study had two main objectives: to determine seroprevalence of HBV, HCV, HIV and syphilis in blood donors of the Yaoundé Central Hospital and to study sociodemographic factors of blood donors. PATIENTS AND METHODS: A retrospective study of consecutive blood donors' records from January to December 2013 was conducted. Seroprevalence of hepatitis B, hepatitis C, human immunodeficiency viruses and syphilis were determined in 9024 whole blood donations collected in the Yaoundé Central Hospital in the centre region, Cameroon using Elisa kits. RESULTS: Mean age of donors was 28 years. The male to female ratio was 14.8. Most of blood donors were replacement donors (97.2%) and first-time donors (76.8%). Up to 19.3% of the donors tested positive for at least one infectious agent, in which 0.1% presented a positive test for three viruses (HIV, HCV and HBV). The overall seroprevalence in blood donors was 12.6% for HBsAg, 3.2% for hepatitis C antibody, 3.3% for HIV-1/2 antibodies and 0.2% for syphilis. The prevalence of HBsAg was significantly higher in men (P=0.001), among first-time donors (P=0.003), in blood group A (P=0.01) and those with the rhesus positive blood (P=0.01). The prevalence of anti-HCV was significantly higher among first-time donors (P=0.05). The prevalence of anti-HIV was significantly higher in first-time donors (3.7% vs 2.2%, P=0.02). CONCLUSION: First-time blood donors and replacement donors are the two types of donors in Cameroon. Replacement donors are considered as having a major risk of transmission of infections to recipients. The seroprevalence of HIV, HBV, HCV, and syphilis among these donors is high and reflects how much these agents are present in Cameroon. Effective infectious markers screening and organization of blood donors into an association of volunteer's donors are necessary to secure blood transfusion in Cameroon.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

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[PMID]: 26778838
[Au] Autor:Mayaki Z; Kabo R; Moutschen M; Albert A; Dardenne N; Sondag D; Gérard C
[Ad] Address:Centre national de transfusion sanguine, BP 2399, Niamey, Niger. Electronic address: mzoubeida@yahoo.fr....
[Ti] Title:Knowledge, attitudes and clinical practice of blood products prescribers in Niamey.
[So] Source:Transfus Clin Biol;23(2):78-85, 2016 May.
[Is] ISSN:1953-8022
[Cp] Country of publication:France
[La] Language:eng
[Ab] Abstract:AIM OF THE STUDY: The lack of traceability and monitoring of blood donors and transfused patients constitute a barrier to the most basic rules of haemovigilance and overall good transfusion practices. This study draws up an inventory of knowledge, attitudes and clinical practice of blood prescribers in Niamey. MATERIALS AND METHODS: A questionnaire was administered to 180 prescribers of blood products in Niamey in 2011. Questions were related to basic informations on blood transfusion and clinical use of blood. Analyses were performed using SAS 9.3 version. RESULTS: The sample consisted of 180 respondents from several professional categories: 51 physicians (28.33%), 10 medical students (5.56%), 84 nurses (46.67%), 15 anaesthesiologist assistant (8.33%) and 20 midwives (11.11%). Among these, 22.2% received training in blood transfusion safety. Half of the respondents (50.8%) got between 50 and 75% of correct answers, 45.8% got less than 50% correct while 3.35% scored more than 75% correct answers. The overall quality of responses was higher among physicians compared to other prescribers (P<0.0001); among respondents who received training in transfusion safety (P<0.0001); and among males (P=0.0306). For some items, subjects with more experience scored the best. CONCLUSION: The level of knowledge is still inadequate. More training in transfusion practices is necessary for prescribers of blood products. Accompanying measures to improve transfusion practice must be considered or strengthened through assessments, knowledge update/upgrade (regular, ongoing training) and establishment of active and motivated hospital transfusion committees.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:IM
[St] Status:In-Data-Review

  7 / 4445861 MEDLINE  
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[PMID]: 27169604
[Au] Autor:Chesney TR; Nadler A; Acuna SA; Swallow CJ
[Ad] Address:Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada. Electronic address: tyler.chesney@gmail.com....
[Ti] Title:Outcomes of resection for locoregionally recurrent colon cancer: A systematic review.
[So] Source:Surgery;160(1):54-66, 2016 Jul.
[Is] ISSN:1532-7361
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: The value of resection for locoregionally recurrent colon cancer (LRCC) is controversial. We aimed to describe the outcomes of resection for LRCC. METHODS: A systematic search in MEDLINE, EMBASE, and Cochrane CENTRAL identified 9 retrospective, uncontrolled cohort studies reporting overall survival following resection of LRCC in 550 patients. Outcomes were pooled using random effects models. RESULTS: Postoperative morbidity was frequent (41.5%), but 30-day mortality was low (2.1%). R0 resection was achieved in 191 (50.6%) patients with a pooled rerecurrence of 25% and was associated with 3-year overall survival of 58% (95% confidence interval: 39-76) and 5-year overall survival of 52% (32-72). By contrast, R1 resection (n = 60) was associated with inferior survival: 3-year overall survival of 27% (12-41) and 5-year overall survival of 11% (2-25). Following macroscopically incomplete resection (R2, n = 86), 3-year overall survival was 11% (5-7) with no 5-year survivors. CONCLUSION: The available literature suggests that resection can be performed safely, with long-term survival expected in about one half of patients who undergo microscopically complete resection. However, it cannot be ascertained whether these favorable outcomes are the result of patient selection or if they can be attributed to resection. Creating a prospective registry of all patients with LRCC would be a step toward addressing the lack of quality evidence for this intervention.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review

  8 / 4445861 MEDLINE  
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[PMID]: 27129932
[Au] Autor:Thiels CA; Hanson KT; Chawla KS; Topazian MD; Paley KH; Habermann EB; Bingener J
[Ad] Address:Department of Surgery, Mayo Clinic, Rochester, MN; Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Rochester, MN....
[Ti] Title:Functional gallbladder disease: Operative trends and short-term outcomes.
[So] Source:Surgery;160(1):100-5, 2016 Jul.
[Is] ISSN:1532-7361
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Due to increasing rates of functional gallbladder disease (FGBD), we used national data to compare rates, patient characteristics, and outcomes of cholecystectomy for FGBD with the more defined diagnosis of biliary colic. METHODS: The American College of Surgeons National Surgical Quality Improvement Program was reviewed for elective cholecystectomies from 2005-2013. The proportion of cholecystectomies performed for FGBD was assessed over time using a 2-sided Cochran-Armitage test for trend. Cholecystectomy for FGBD was compared with that for biliary colic using univariate analysis, multivariable logistic, and Cox proportional hazard regressions. RESULTS: Of 156,322 patients undergoing cholecystectomy, 5,161 (3.3%) had FGBD. FGBD as an indication for cholecystectomy remained stable over time (3.4% in 2006 to 3.2% in 2013, P = .29). Compared with biliary colic, patients with FGBD were more likely <50 years old, non-Hispanic white, female, and had a body mass index <25 (all P < .001), while comorbidities were similar (P > .05). While differences in outcomes were seen on univariate analysis, on multivariable analysis, only duration of stay was significantly less for FGBD than biliary colic. Surgery residents were involved in 61.2% of the biliary colic versus 53.9% of FGBD cases (P < .001). CONCLUSION: The rate of FGBD as an indication for cholecystectomy is not increasing overall, but cholecystectomy may be more commonly performed at nonacademic hospitals. While cholecystectomy for FGBD appears safe, the outcomes are comparable to cholecystectomy for biliary colic and thus are not without risk.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review

  9 / 4445861 MEDLINE  
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[PMID]: 27106794
[Au] Autor:Klaiber U; Alldinger I; Probst P; Bruckner T; Contin P; Köninger J; Hackert T; Büchler MW; Diener MK
[Ad] Address:Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany; Study Center of the German Surgical Society, University of Heidelberg, Heidelberg, Germany....
[Ti] Title:Duodenum-preserving pancreatic head resection: 10-year follow-up of a randomized controlled trial comparing the Beger procedure with the Berne modification.
[So] Source:Surgery;160(1):127-35, 2016 Jul.
[Is] ISSN:1532-7361
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Since the introduction of the duodenum-preserving pancreatic head resection for operative treatment of chronic pancreatitis, various modifications of the original Beger procedure have emerged. A randomized controlled trial comparing the Beger procedure and the Berne modification indicated that the latter is an equivalent alternative, but a comparison of the long-term results of both procedures has not yet been published. METHODS: Between December 2002 and January 2005, 65 patients were randomized intraoperatively to the Beger or the Berne procedure. For this 10-year follow-up, patients were contacted by phone and in writing to evaluate patient-relevant outcome parameters. Statistical analysis was made on an intention-to-treat basis. RESULTS: Median follow-up was 129 (111-137) months. Forty of 65 patients were available for follow-up; 11 of the original study cohort had died, and 14 were otherwise lost to follow-up. Quality of life, pain, occupational disability, exocrine and endocrine pancreatic function, endoscopic interventions, and redo operations were comparable in both groups. More than half of the patients were completely free of pain, and the majority in both groups judged that the index operation had improved their quality of life. CONCLUSION: Ten-year follow-up showed no differences in patient-relevant outcome parameters between the Beger and Berne procedures for treatment of chronic pancreatitis. Because short-term results have shown the Berne modification is superior in terms of operation time and duration of hospital stay, it should be preferred whenever possible, depending on the individual surgeon's expertise and the intraoperative findings.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review

  10 / 4445861 MEDLINE  
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[PMID]: 27085686
[Au] Autor:Kim Y; Gani F; Canner JK; Margonis GA; Makary MA; Schneider EB; Pawlik TM
[Ad] Address:Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD....
[Ti] Title:Hospital readmission after multiple major operative procedures among patients with employer provided health insurance.
[So] Source:Surgery;160(1):178-90, 2016 Jul.
[Is] ISSN:1532-7361
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Most studies report data only on readmission within 30 days of discharge from the same hospital following a single procedure. We sought to define the incidence of early versus late hospital readmission among patients undergoing multiple major operative procedures. METHODS: Patients were identified using the MarketScan database from 2010-2012. Multivariable logistic regression analysis was performed to identify factors associated with early (≤30 days) versus late readmission (31-90 days) among patients who underwent multiple operative procedures. RESULTS: A total of 194,111 patients were identified of whom 63.2% (n = 122,660) underwent an abdominal procedure (esophagectomy, pancreatectomy, hepatectomy, colectomy, lung resection, and gastrectomy), while the remaining 71,451 (36.8%) patients underwent a cardiovascular procedure (repair of abdominal aortic aneurysm, coronary-artery bypass grafting, carotid endarterectomy, and mitral/aortic valve replacement). A total of 3,444 patients underwent >1 simultaneous procedure (abdominal: 885, 0.7%; cardiovascular: 2,559, 3.6%). The overall incidence of 90-day readmission was 15.6% (n = 30,309); 9.6% of patients were readmitted early, while 6.0% of patients were readmitted late. Readmission was higher among patients undergoing multiple procedures (21.8% vs 15.5%; P < .001). On multivariable analysis, patients undergoing multiple operative procedures demonstrated a 20% greater odds of readmission compared with patients undergoing a single operative procedure (abdominal: odds ratio 1.18, 95% confidence interval 1.01-1.37; P = .03; cardiovascular: odds ratio 1.18, 95% confidence interval 1.06-1.31; P = .002). Other risk factors independently associated with increased odds for early and late readmission included a higher preoperative comorbidity, postoperative discharge with additional care, an increasing duration of stay, and the development of postoperative complications (all P < .05). CONCLUSION: Readmission following a major operation is common, with >15% of patients being readmitted within 90 days of index discharge. Compared with patients undergoing a single operative procedure, patients undergoing multiple operative procedures demonstrated an increased risk for readmission within 90 days of discharge and were more likely to be readmitted within 30 days of index discharge.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1606
[Js] Journal subset:AIM; IM
[St] Status:In-Data-Review


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