Database : MEDLINE
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[PMID]: 28459250
[Au] Autor:Petrungaro PS
[Ad] Address:Private Practice, Periodontics and Implantology, Chicago, Illinois; Founder and Director, The Implant Learning Center, Chicago, Illinois.
[Ti] Title:Options for the Esthetic Zone Using the Immediate Restoration Procedure: Observational Data of 15 Years and 5000 Implants.
[So] Source:Compend Contin Educ Dent;38(5):318-325, 2017 May.
[Is] ISSN:2158-1797
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Dental implants have become a suitable treatment option for patients experiencing tooth loss and a popular choice among clinicians for immediate tooth replacement. Because of modifications in implant designs and development in immediate restoration and loading protocols, dental implant treatment can be reduced to a single procedure instead of multiple processes, hence providing the patient with a streamlined treatment that is typically much less invasive with immediate-tooth replacement. The purpose of this paper is to review the immediate restoration of dental implant(s) procedure and validate its position in treatment protocols by presenting success rates documented for more than 15 years and with 5000 implants. Also, recommendations for the management of different alveolar contours and defects will be presented, which have been encountered by the author when performing the immediate restoration procedure throughout this 15-year period.
[Mh] MeSH terms primary: Dental Implantation, Endosseous/methods
Dental Implants
Dental Restoration, Permanent/methods
Esthetics, Dental
[Mh] MeSH terms secundary: Adult
Alveolar Bone Loss
Dental Implants, Single-Tooth
Dental Prosthesis, Implant-Supported
Female
Humans
Immediate Dental Implant Loading
Male
Middle Aged
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Dental Implants)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:D
[Da] Date of entry for processing:170502
[St] Status:MEDLINE

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[PMID]: 28449764
[Au] Autor:Brignardello-Petersen R
[Ti] Title:Probing depth and implant location are risk factors for bleeding on probing around dental implants.
[So] Source:J Am Dent Assoc;148(5):e60, 2017 05.
[Is] ISSN:1943-4723
[Cp] Country of publication:England
[La] Language:eng
[Mh] MeSH terms primary: Dental Implantation, Endosseous
Dental Implants
[Mh] MeSH terms secundary: Alveolar Bone Loss
Dental Plaque Index
Dental Prosthesis Design
Dental Prosthesis, Implant-Supported
Humans
Periodontal Index
Risk Factors
[Pt] Publication type:REVIEW; COMMENT
[Nm] Name of substance:0 (Dental Implants)
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[Js] Journal subset:D; IM
[Da] Date of entry for processing:170429
[St] Status:MEDLINE

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[PMID]: 29498126
[Au] Autor:Sanz-Sánchez I; Carrillo de Albornoz A; Figuero E; Schwarz F; Jung R; Sanz M; Thoma D
[Ad] Address:Section of Graduate Periodontology, University Complutense, Madrid, Spain.
[Ti] Title:Effects of lateral bone augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis.
[So] Source:Clin Oral Implants Res;29 Suppl 15:18-31, 2018 Mar.
[Is] ISSN:1600-0501
[Cp] Country of publication:Denmark
[La] Language:eng
[Ab] Abstract:OBJECTIVES: This systematic review evaluated the evidence on the effect of the interventions aimed for lateral ridge augmentation (both simultaneously with implant placement or as a staged procedure) on peri-implant health or disease. METHODS: A protocol was developed to answer the following PICO question: "In patients with horizontal alveolar ridge deficiencies (population), what is the effect of lateral bone augmentation procedures (intervention and comparison) on peri-implant health (outcome)?" Included studies were randomised controlled trials or controlled clinical trials with a follow-up of at least 12 months after implant loading. Meta-analyses were performed whenever possible, including subgroup analysis based on follow-up. RESULTS: Twelve final publications from eight investigations were included. The results from the meta-analysis indicated that irrespective of the type of intervention, the inflammatory changes, based on bleeding on probing (%) were minimal, both at short- (n = 1; weighted mean difference [WMD] = -1.00; 95% CI [-14.04; 12.04]; p = .881) and long-term (n = 5; WMD = -5.63; 95% CI [-18.42; 7.16]; p = .881). When comparing different treatment modalities, no significant differences were observed (n = 6; WMD = -3.36; 95% CI [-12.49; 5.77]; p < .471). Similarly, changes in probing pocket depth and marginal bone levels were not significantly different among groups. The incidence of peri-implantitis was evaluated in three investigations and varied from 16% to 26% after a follow-up period of 6-8 years. CONCLUSIONS: The results from this systematic review and meta-analysis have shown that lateral ridge augmentation procedures can maintain peri-implant health over time with low mucosal inflammatory changes and a relatively small incidence of peri-implant bone loss.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[St] Status:In-Process
[do] DOI:10.1111/clr.13126

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[PMID]: 29478251
[Au] Autor:Chiapasco M; Casentini P
[Ti] Title:Horizontal bone-augmentation procedures in implant dentistry: prosthetically guided regeneration.
[So] Source:Periodontol 2000;, 2018 Feb 25.
[Is] ISSN:1600-0757
[Cp] Country of publication:Denmark
[La] Language:eng
[Ab] Abstract:The rehabilitation of partially or totally edentulous patients with implant-supported prostheses has become routine, with excellent long-term outcome. A proper implant position is mandatory to achieve good functional and esthetic outcome and may require an adequate amount of alveolar bone and surrounding soft tissue. When this is lacking because of atrophy, sequelae of periodontal disease, traumas or congenital malformations, increased bone volume and/or keratinized mucosa can be obtained by guided bone regeneration, bone-grafting techniques and alveolar bone expansion. This article presents an evidence-based, prosthetically driven approach for the treatment of edentulous ridges with horizontal defects. The classification of bony defects, the main augmentation techniques, the selection criteria among different surgical procedures for different types of bony defects, and the advantages, disadvantages and limitations of each technique, are described in detail.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1802
[Cu] Class update date: 180225
[Lr] Last revision date:180225
[St] Status:Publisher
[do] DOI:10.1111/prd.12219

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[PMID]: 29185644
[Au] Autor:Soolari A
[Ti] Title:Management of a Nontreatable Mandibular Anterior Tooth.
[So] Source:Dent Today;35(11):105-8, 2016 Nov.
[Is] ISSN:8750-2186
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Alveolar Bone Loss/surgery
Dental Implants
[Mh] MeSH terms secundary: Aged
Female
Humans
Incisor
Mandible
Patient Care Team
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Dental Implants)
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[Js] Journal subset:D
[Da] Date of entry for processing:171201
[St] Status:MEDLINE

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[PMID]: 29275569
[Au] Autor:Ren XY; Wang C; Liu X; Li H; Gao JH; Ge XJ
[Ad] Address:Department of Periodontology, Shanxi Medical University, Taiyuan 030001, China.
[Ti] Title:[Establishment of rat model with diabetes mellitus and concomitant periodontitis and the carotid artery lesions in the model rats].
[So] Source:Zhonghua Kou Qiang Yi Xue Za Zhi;52(12):747-752, 2017 Dec 09.
[Is] ISSN:1002-0098
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To establish SD rat model with type 2 diabetes mellitus (DM) and concomitant chronic periodontitis (CP) and to evaluate the influence of periodontitis on the vascular lesions of type 2 diabetes rats. Totally 241 clean level SD rats were randomly divided into four groups, group A (normal control, NC, 27), group B (DM, 34), group C (CP, 90) and group D (DM+CP, 90). The rats of DM group were fed with high-fat and high-sugar diet for 8 to 10 weeks, and then were multiply injected with small dose streptozotocin under the condition of ice bath. Blood sugar levels after the injection were dynamically monitored at 72 h, 1 week, 2 weeks and 4 weeks, respectively. The CP model was established by means of ligation. Bilateral maxillary first and second molars were selected and ligated using 0.2 mm orthodontic wires binding with 4-0 surgical suture soaked with (Pg) suspension. After a period of 14 weeks, all the rats were put to death. Maxillary samples were subjected to methylene blue staining to observe alveolar bone loss. Bilateral carotid artery specimens were collected. The left carotid artery specimens were used to detect the prevalence of Pg using quantitative real-time PCR. The right carotid artery specimens were used to observe pathological changes. Blood sugar levels of rats in group B and D increased and changed sharply after Streptozotocin injection with in 1 week. Symptoms of 'more drink, more food and body weight loss' appeared. The fasting blood glucose (FBG) was more than 7.8 mmol/L and (or) the random blood glucose (RBG) was more than 17.8 mmol/L. Both FBG and RBG became stable after 2 to 3 weeks. Levels of HbA1C in group B and D ([7.32±0.45]%, [9.41±0.45]%) were significantly higher than that of group A ([4.02±0.45]%) ( 0.01). Rats of group D were observed the most severe bone loss showing wider interdental space and furcation involvement. Pathological results of carotid artery tissues of group D showed the worst lesions including thinning and calcification of vessel walls, and breaking down or disappearance of elastic fibers. The prevalences of DNA of Pg in groups of A, B, C and D were 3/7, 3/7, 6/7 and 7/7, respectively. The bacteria numbers detected by quantitative real-time PCR in groups C and D were significantly higher than that of groups A and B ( 0.01). Rat model of type 2 DM with periodontitis was successfully established in the present study. Carotid artery specimens from DM+CP model rats showed typical vascular lesions such as calcification and fiber disorders. Pg was found in all carotid specimens and the highest bacteria numbers were detected in the composite model rats. The Pg might play a role in the progress of diabetes vascular lesions.
[Mh] MeSH terms primary: Carotid Arteries/pathology
Carotid Artery Diseases/pathology
Chronic Periodontitis/pathology
Diabetes Mellitus, Experimental/pathology
Diabetes Mellitus, Type 2/pathology
[Mh] MeSH terms secundary: Alveolar Bone Loss/diagnosis
Alveolar Bone Loss/pathology
Animals
Blood Glucose/analysis
Carotid Arteries/microbiology
Carotid Artery Diseases/microbiology
Chronic Disease
Chronic Periodontitis/microbiology
Diabetes Mellitus, Experimental/chemically induced
Diabetes Mellitus, Type 2/chemically induced
Disease Progression
Glycated Hemoglobin A/metabolism
Maxilla
Porphyromonas gingivalis
Random Allocation
Rats
Rats, Sprague-Dawley
Real-Time Polymerase Chain Reaction
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Blood Glucose); 0 (Glycated Hemoglobin A)
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[Js] Journal subset:D; IM
[Da] Date of entry for processing:171226
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1002-0098.2017.12.007

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[PMID]: 29275568
[Au] Autor:Wang ZX; Yang L; Tan JY; Chen LL
[Ad] Address:Department of Periodontology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
[Ti] Title:[Effects of T helper 1 cells and T helper 17 cells secreting cytokines on rat models of experimental periodontitis].
[So] Source:Zhonghua Kou Qiang Yi Xue Za Zhi;52(12):740-747, 2017 Dec 09.
[Is] ISSN:1002-0098
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:To investigate the effects of secreting cytokines interferon-gamma (IFN-γ) and interleukin-17 (IL-17) of T helper 1 cells (Th1) and T helper 17 cells (Th17) on the peripheral blood and alveolar bone destruction, so as to provide a new explanation for cellular immunity-mediated alveolar bone destruction. Eighteen eight-week-old male Sprague-Dawley rats were divided, randomly and equally, into 3 groups: lipopolysaccharide (LPS) group, ligation group and normal control group. In the LPS group, LPS was injected into the alveolar mucosa on the buccalmedian site of the left upper first molar, while the right upper first molar was injected with equal volume of physiological saline as self-controls. The injections were performed every other day for four times totally. In the ligation group, the left upper first molars were ligatured with 0.2 mm orthodontic cords, while the right upper first molars were left untreated as self-controls, and supplemented with high-sugar diet to promote the periodontitis status. The rats in normal control group were fed normally. The concentrations of IFN-γ and IL-17 in peripheral blood were measured using enzyme linked immunosorbent assay (ELISA) method at the fourth week after the start of injection and at the eighth week after ligation. The histological of periodontal tissues were observed after hematoxylin-eosin (HE) staining and osteoclast count was performed under light microscope. The histological of osteoclasts were observed after tartrate-resistant acid phosphatase (TRAP) staining. Expression of IFN-γ and IL-17 were detected by immunohistochemical assay. The concentrations of IFN-γ in peripheral blood of LPS group [(185.0±50.7) ng/L] and ligation group [(202.9±60.4) ng/L] were significantly higher than that of normal control group [(106.3±17.2) ng/L]( 0.05). Meanwhile, histological examination showed inflammatory cells infiltration in the gingival epithelium, the height reduction of alveolar bone accompanied with absorption lacuna. There were significantly higher HE and TRAP stained osteoclasts in LPS group (9.50±1.05) and ligation group (10.83±1.17) than that in controlgroup (0.33±0.52)( 0.05). Moreover, the expressions of IL-17 in alveolar bone absorption area of LPS group and ligation group were significantly stronger than that in control group ( 0.05). The rat models of experimental periodontitis and alveolar bone resorption could be successfully established by means of ligationand LPS injection, respectively. The periodontal inflammatory responses were related to secreting cytokines IFN-γ and IL-17 of Th1 and Th17 cells, while Th17 cells might exert a positive effect on alveolar bone destruction.
[Mh] MeSH terms primary: Alveolar Bone Loss/immunology
Interferon-gamma/secretion
Interleukin-17/secretion
Periodontitis/metabolism
Th1 Cells/secretion
Th17 Cells/secretion
[Mh] MeSH terms secundary: Alveolar Bone Loss/metabolism
Animals
Disease Models, Animal
Escherichia coli
Interferon-gamma/blood
Interleukin-17/blood
Ligation
Lipopolysaccharides
Male
Osteoclasts/cytology
Periodontitis/etiology
Periodontitis/pathology
Random Allocation
Rats
Rats, Sprague-Dawley
Tartrate-Resistant Acid Phosphatase
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (IL17 protein, rat); 0 (Interleukin-17); 0 (Lipopolysaccharides); 82115-62-6 (Interferon-gamma); EC 3.1.3.2 (Tartrate-Resistant Acid Phosphatase)
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[Js] Journal subset:D; IM
[Da] Date of entry for processing:171226
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1002-0098.2017.12.006

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[PMID]: 29236918
[Au] Autor:Silveira-Neto N; Flores ME; De Carli JP; Costa MD; Matos FS; Paranhos LR; Linden MSS
[Ad] Address:Departamento de Odontologia, Universidade de Passo Fundo, Passo Fundo, RS, BR.
[Ti] Title:Peri-implant assessment via cone beam computed tomography and digital periapical radiography: an ex vivo study.
[So] Source:Clinics (Sao Paulo);72(11):708-713, 2017 Nov.
[Is] ISSN:1980-5322
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:OBJECTIVES: This research evaluated detail registration in peri-implant bone using two different cone beam computer tomography systems and a digital periapical radiograph. METHODS: Three different image acquisition protocols were established for each cone beam computer tomography apparatus, and three clinical situations were simulated in an ex vivo fresh pig mandible: buccal bone defect, peri-implant bone defect, and bone contact. Data were subjected to two analyses: quantitative and qualitative. The quantitative analyses involved a comparison of real specimen measures using a digital caliper in three regions of the preserved buccal bone - A, B and E (control group) - to cone beam computer tomography images obtained with different protocols (kp1, kp2, kp3, ip1, ip2, and ip3). In the qualitative analyses, the ability to register peri-implant details via tomography and digital periapical radiography was verified, as indicated by twelve evaluators. Data were analyzed with ANOVA and Tukey's test (α=0.05). RESULTS: The quantitative assessment showed means statistically equal to those of the control group under the following conditions: buccal bone defect B and E with kp1 and ip1, peri-implant bone defect E with kp2 and kp3, and bone contact A with kp1, kp2, kp3, and ip2. Qualitatively, only bone contacts were significantly different among the assessments, and the p3 results differed from the p1 and p2 results. The other results were statistically equivalent. CONCLUSIONS: The registration of peri-implant details was influenced by the image acquisition protocol, although metal artifacts were produced in all situations. The evaluators preferred the Kodak 9000 3D cone beam computer tomography in most cases. The evaluators identified buccal bone defects better with cone beam computer tomography and identified peri-implant bone defects better with digital periapical radiography.
[Mh] MeSH terms primary: Alveolar Bone Loss/diagnostic imaging
Dental Implants
Mandible/diagnostic imaging
Periapical Diseases/diagnostic imaging
[Mh] MeSH terms secundary: Animals
Cone-Beam Computed Tomography
Radiography, Dental, Digital
Reproducibility of Results
Swine
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dental Implants)
[Em] Entry month:1801
[Cu] Class update date: 180129
[Lr] Last revision date:180129
[Js] Journal subset:IM
[Da] Date of entry for processing:171214
[St] Status:MEDLINE

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[PMID]: 29231671
[Au] Autor:Kirtley GE
[Ti] Title:The Aesthetic Zone Challenge.
[So] Source:Dent Today;36(6):74, 76-7, 2017 Jun.
[Is] ISSN:8750-2186
[Cp] Country of publication:United States
[La] Language:eng
[Mh] MeSH terms primary: Dental Implantation, Endosseous
Dental Prosthesis, Implant-Supported
Esthetics, Dental
Incisor/abnormalities
Maxilla/abnormalities
[Mh] MeSH terms secundary: Adolescent
Alveolar Bone Loss
Female
Humans
Smiling
Tooth Discoloration
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180115
[Lr] Last revision date:180115
[Js] Journal subset:D
[Da] Date of entry for processing:171213
[St] Status:MEDLINE

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[PMID]: 29240821
[Au] Autor:Kim JH; Kim AR; Choi YH; Jang S; Woo GH; Cha JH; Bak EJ; Yoo YJ
[Ad] Address:Department of Oral Biology, Yonsei University College of Dentistry, Seoul, Republic of Korea.
[Ti] Title:Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis.
[So] Source:PLoS One;12(12):e0189702, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Type 1 diabetes with periodontitis shows elevated TNF-α expression. Tumor necrosis factor (TNF)-α stimulates the expression of receptor activator of nuclear factor-κB ligand (RANKL) and sclerostin. The objective of this study was to determine the effect of TNF-α expression of osteocytic RANKL and sclerostin in type 1 diabetes rats with periodontitis using infliximab (IFX), a TNF-α antagonist. Rats were divided into two timepoint groups: day 3 and day 20. Each timepoint group was then divided into four subgroups: 1) control (C, n = 6 for each time point); 2) periodontitis (P, n = 6 for each time point); 3) diabetes with periodontitis (DP, n = 8 for each time point); and 4) diabetes with periodontitis treated with IFX (DP+IFX, n = 8 for each time point). To induce type 1 diabetes, rats were injected with streptozotocin (50 mg/kg dissolved in 0.1 M citrate buffer). Periodontitis was then induced by ligature of the mandibular first molars at day 7 after STZ injection (day 0). IFX was administered once for the 3 day group (on day 0) and twice for the 20 day group (on days 7 and 14). The DP group showed greater alveolar bone loss than the P group on day 20 (P = 0.020). On day 3, higher osteoclast formation and RANKL-positive osteocytes in P group (P = 0.000 and P = 0.011, respectively) and DP group (P = 0.006 and P = 0.017, respectively) than those in C group were observed. However, there was no significant difference in osteoclast formation or RANKL-positive osteocytes between P and DP groups. The DP+IFX group exhibited lower alveolar bone loss (P = 0.041), osteoclast formation (P = 0.019), and RANKL-positive osteocytes (P = 0.009) than that of the DP group. On day 20, DP group showed a lower osteoid area (P = 0.001) and more sclerostin-positive osteocytes (P = 0.000) than P group. On days 3 and 20, the DP+IFX group showed more osteoid area (P = 0.048 and 0.040, respectively) but lower sclerostin-positive osteocytes (both P = 0.000) than DP group. Taken together, these results suggest that TNF-α antagonist can diminish osteocytic RANKL/sclerostin expression and osteoclast formation, eventually recovering osteoid formation. Therefore, TNF-α might mediate alveolar bone loss via inducing expression of osteocytic RANKL and sclerostin in type 1 diabetes rats with periodontitis.
[Mh] MeSH terms primary: Bone Morphogenetic Proteins/metabolism
Diabetes Mellitus, Experimental/metabolism
Infliximab/pharmacology
Osteocytes/drug effects
Periodontitis/metabolism
RANK Ligand/metabolism
Tumor Necrosis Factor-alpha/antagonists & inhibitors
[Mh] MeSH terms secundary: Alveolar Bone Loss
Animals
Diabetes Mellitus, Experimental/complications
Genetic Markers
Immunohistochemistry
Male
Osteocytes/metabolism
Periodontitis/complications
Rats
Rats, Inbred F344
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Bone Morphogenetic Proteins); 0 (Genetic Markers); 0 (RANK Ligand); 0 (Sost protein, rat); 0 (Tumor Necrosis Factor-alpha); B72HH48FLU (Infliximab)
[Em] Entry month:1712
[Cu] Class update date: 171229
[Lr] Last revision date:171229
[Js] Journal subset:IM
[Da] Date of entry for processing:171215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189702


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