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[PMID]: 29521748
[Au] Autor:Figueira JA; Batista FRS; Rosso K; Veltrini VC; Pavan AJ
[Ad] Address:Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP).
[Ti] Title:Delayed Diagnosis of Gorlin-Goltz Syndrome: The Importance of the Multidisciplinary Approach.
[So] Source:J Craniofac Surg;, 2018 Mar 08.
[Is] ISSN:1536-3732
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant inherited disorder with high penetrance and variable expressivity. The classic triad originally described by Gorlin and Goltz in 1960 is composed of multiple nevoid basal cell carcinomas (NBCCs), odontogenic keratocysts (OKCs) in the jaws and bifid ribs. in 1977, this triad was modified by Rayner et al, and to GGS diagnosis, the OKCs had to appear in combination with calcification of the cerebellar falx or palmar and plantar pits. It may occur that although GGS syndrome is a well-known condition, only the specific symptom could be observed by different specialists. Therefore, the patient cannot be placed in an always complex clinical panel. The authors introduce an example in this report. In the present case, the patient had NBCCs, OKCs, and probably other signs of GGS since 1998, and has been treated for this conditions separated, without a diagnosis of a syndromic condition. A 54-year-old white woman was referred to the oral medicine service due to cyst located in the right mandibular body. She had history of skin cancer and undergone surgeries and radiotherapies for the lesions treatment, scars on the skin face due to the lesions removed, and a new ulcerated lesion on the back of was diagnosed. In addition, the patient presented frontal and parietal bossing leading to increased cranial circumference, hypertelorism, strabismus, broad base, and mandibular prognathism. To the image examination, skull radiography revealed calcification of the falx cerebri; on chest X-ray bifid rib was observed and spine radiography showed vertebral osteophytes. Panoramic radiograph showed a well-defined bilocular radiolucent image located in posterior and anterior mandibular region. The whole elements induced us to investigate the patient's past medical history, which revealed that since 1998 had the diagnosis of NBCC and OKC. A multidisciplinary approach becomes necessary for the diagnosis and follow-up of patients with GGS, considering the complexity of the clinical manifestations. Therefore, it is of primary importance for dental surgeons and dermatologists to know the signs and symptoms of GGS to perform early diagnosis and to avoid progression of the oral cysts or metastasis of the skin lesions.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1097/SCS.0000000000004438

  2 / 6113 MEDLINE  
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[PMID]: 29520625
[Au] Autor:Kreitschmann-Andermahr I; Kohlmann J; Kleist B; Hirschfelder U; Buslei R; Buchfelder M; Siegel S
[Ad] Address:Department of Neurosurgery, University of Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany. ilonka.kreitschmann@uk-essen.de.
[Ti] Title:Oro-dental pathologies in acromegaly.
[So] Source:Endocrine;, 2018 Mar 08.
[Is] ISSN:1559-0100
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Oro-dental pathologies (ODP) such as enlargement of the tongue, mandibular prognathism, and spaced teeth are characteristic features of acromegaly. Their frequency of occurrence during the course of the disease is largely unresolved. Purpose of this study was to assess ODP and oro-dental treatments in patients with acromegaly with regard to the length of the diagnostic process, tumor histology, and quality of life (QoL). METHODS: Single-center retrospective survey study using questionnaires on dental symptoms, diagnostic process, and treatment in patients with acromegaly operated on a growth hormone-secreting pituitary adenoma. The association between ODP and QoL was assessed using the Short-Form 36 (SF-36) Health Survey. RESULTS: 145/314 patients completed the questionnaires. 80.7% were affected by any ODP, most frequently enlargement of the tongue (57.9%), spaced teeth (42.8%), mandibular growth (24.1%), and mandibular prognathism (22.1%). ODP were significantly more frequent in patients with sparsely vs. densely granulated adenomas (p = 0.045). Early diagnosis within 2 years was associated with significantly fewer ODP than later diagnosis (68.5 vs. 87.2%, p = 0.009). Treatments included dental crowns (16.6%), dental bridges (12.4%), dental implants (9.7%), dental prostheses (3.4%), orthodontal (i.e., braces, 6.9%), and surgical correction of the teeth (2.1%). Physical QoL was significantly lower in patients with ODP than in those without (p = 0.014). CONCLUSION: In our large series of patients, four of five patients were affected by ODP at any time during the course of the disease. The results highlight the importance of early identification and treatment of oro-dental problems in patients with acromegaly as hallmarks of the disease.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1007/s12020-018-1571-y

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[PMID]: 29189406
[Au] Autor:Farrow E; Nicot R; Wiss A; Laborde A; Ferri J
[Ad] Address:Department of Oral and Maxillofacial Surgery, University of Lille, CHU Lille.
[Ti] Title:Cleidocranial Dysplasia: A Review of Clinical, Radiological, Genetic Implications and a Guidelines Proposal.
[So] Source:J Craniofac Surg;29(2):382-389, 2018 Mar.
[Is] ISSN:1536-3732
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In this review, we aimed to depict the clinical, radiological, and genetic features of cleidocranial dysplasia (CCD) and to suggest management guidelines, based on our experience of 8 cases, with an emphasis given to dental complications.The most common craniofacial features of CCD that stand out are a patency of the anterior fontanelle, an inverted pear-shaped calvaria, a hypertelorism, a general midface retrusion, and a mandible prognathism, associated with an excessive mobility of the shoulders, a short stature, and teeth abnormalities such as supernumerary teeth and failure of eruption, in particular. RUNX2 is the only gene in which mutation is known to cause CCD, but mutations are detected in only 65% of all patients with a clinical diagnosis of CCD. Panoramic radiography is a valuable adjunct in confirming the diagnosis of CCD.Our experience allowed us to conclude that orthodontically aided eruption should always be attempted. However, to stabilize the occlusion and to improve facial esthetics, we recommend associated orthognathic surgery. When orthodontic treatment is partially efficient, prosthetic treatment options bring satisfactory results, in terms of occlusion. Nevertheless, when orthodontic treatment fails, we recommend to preserve as many native teeth as possible, and to combine orthognathic preprosthetic surgery and implant-supported prosthesis.In any case, an individualized treatment protocol, depending on the needs and demand of the patient, the age at diagnosis and social and economic circumstances, should be put forward.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Process
[do] DOI:10.1097/SCS.0000000000004200

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[PMID]: 28449763
[Au] Autor:Brignardello-Petersen R
[Ti] Title:Early orthodontic treatment produces short-term dental and skeletal changes in patients with Class III malocclusions.
[So] Source:J Am Dent Assoc;148(5):e59, 2017 05.
[Is] ISSN:1943-4723
[Cp] Country of publication:England
[La] Language:eng
[Mh] MeSH terms primary: Malocclusion, Angle Class III
Mandible
[Mh] MeSH terms secundary: Cephalometry
Dental Care
Humans
Malocclusion
[Pt] Publication type:REVIEW; COMMENT
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[Js] Journal subset:D; IM
[Da] Date of entry for processing:170429
[St] Status:MEDLINE

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[PMID]: 29425750
[Au] Autor:Han YS; Lee H
[Ad] Address:Clinical Professor, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Seoul, Korea; Researcher, Department of Oral and Maxillofacial Surgery, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Korea.
[Ti] Title:The Influential Bony Factors and Vectors for Predicting Soft Tissue Responses After Orthognathic Surgery in Mandibular Prognathism.
[So] Source:J Oral Maxillofac Surg;, 2018 Jan 31.
[Is] ISSN:1531-5053
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: We sought to identify the hard tissue points and vectors that have the greatest effect on soft tissue movement after orthognathic surgery in patients with mandibular prognathism. PATIENTS AND METHODS: The present retrospective study involved patients who had undergone mandibular setback surgery with or without maxillary advancement. Multiple linear regression models were adapted to evaluate the association between the 8 hard tissue landmark (predictor variables) changes and 11 soft tissue responses (outcome variables) using the x and y coordinates assessed from superimposed pre- and postoperative 3-dimensional computed tomography images. RESULTS: A total of 50 patients (42 patients had undergone 2-jaw surgery; 8 patients had undergone 1-jaw surgery; mean age 23 ± 4 years) were included in the present study. Our statistical models demonstrated that the horizontal hard tissue changes had a greater influence on the soft tissue responses than did the vertical changes, and these changes were more notable in the lower facial area (lower lip contour and chin profile) than the midfacial area (nasal profile, upper lip contour, upper lip length, and nasolabial angle). In the horizontal soft tissue response model, the soft tissue A point/A point ratio was 0.86:1 (95% confidence interval [CI] 0.674-1.049); the soft tissue B point/B point ratio was almost 1:1 (95% CI 0.919-1.071); and the soft tissue pogonion/pogonion ratio was 0.88:1 (95% CI 0.805-0.963). CONCLUSIONS: Horizontal or vertical bone tissue changes affected both the horizontal and vertical soft tissue changes in most areas. Our study demonstrated that the soft tissue response is not linear but a more complicated and dynamic reaction.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:Publisher

  6 / 6113 MEDLINE  
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[PMID]: 29478982
[Au] Autor:Kuroedova VD; Stasiuk AA; Makarova AN; Trofimenko KL; Vyzhenko EE
[Ad] Address:Department Of Post-Graduate Education Of Orthodontists, Educational And Research Institute Of Post-Graduate Education, Higher State Educational Establishment Of Ukraine «Ukrainian Medical Stomatological Academy¼, Poltava, Ukraine.
[Ti] Title:Symmetry of elements of temporomandibular joint (TMJ).
[So] Source:Wiad Lek;70(6 pt 1):1079-1082, 2017.
[Is] ISSN:0043-5147
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Introduction: Dysfunction of temporomandibular joint is present in 70-75% of orthodontic patients. Evaluation of TMJ and detailed characteristics of its elements with additional methods of examination in children and adults is necessary for clinical definition of proposed disturbances of the structure and functions of the joint. The aim of the investigation is to study morphological symmetry of TMJ in patients with dentofacial abnormalities and with dentofacial abnormalities complicated by secondary edentulism. PATIENTS AND METHODS: Materials and Methods: 57 patients were involved in the examination. Based on gender principle patients' distribution was almost equal: there were 30 women and 27 men. Cone-beam computerized tomography (CBCT) Galileos (SIRONA DENTAL, Germany) was used to all patients. RESULTS: Results: It was done analysis of parameters (height and length) of right and left heads (condyles) of temporomandibular joint in both groups. Asymmetry of parameters of heads' length in saggital area in patients of the second group was defined. It was proved statistically (left 10,38±0,76, right 8,16±0,78). CONCLUSION: Conclusions: Increase of asymmetry of length of heads of TMJ in saggital area with age was determined. It can be explained by complication of dentofacial abnormalities and the presence of secondary edentulism. Depending on bite type length of condyle, especially at prognathism (in saggital) area peculiar clinical problems with TMJ can be present due to asymmetry of condyles. The size of joint gaps of TMJ due to the presence of dentofacial abnormalities with age demonstrates compensatory ability and saves its.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:In-Data-Review

  7 / 6113 MEDLINE  
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[PMID]: 29406261
[Au] Autor:Kokuryo S; Habu M; Kita R; Katsuki T; Tominaga K; Yoshioka I
[Ad] Address:Assistant Professor, Division of Oral Medicine, Department of Physical Functions, Kyushu Dental University, Kitakyushu, Japan.
[Ti] Title:Comparison of the Effects of Ultrasonic and Conventional Surgery on the Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy.
[So] Source:J Oral Maxillofac Surg;, 2018 Jan 03.
[Is] ISSN:1531-5053
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: According to the literature, ultrasonic surgery reduces the incidence of neurosensory disturbance (NSD) of the inferior alveolar nerve (IFAN) after bilateral sagittal split osteotomy (BSSO). The purpose of this study was to evaluate the effects of ultrasonic surgery and the anatomic position of the IFAN canal on NSD after BSSO. PATIENTS AND METHODS: This retrospective cohort study included skeletal mandibular prognathism cases operated on with an ultrasonic bone scalpel or a reciprocating saw. The primary predictor variable was osteotomy technique (ultrasonic or conventional surgery). The primary outcome variable was NSD. Other variables included age, gender, operator, degree of setback, surgical duration, blood loss, and IFAN position. Comparisons of 2 variables were performed by use of the Student t test or Fisher exact test. A regression model was used to examine the relationship between the presence or absence of NSD and other variables. The level of significance was set at P < .05 for all statistical tests. RESULTS: The ultrasonic group was composed of 35 patients, whereas the conventional group was composed of 32. Three months after surgery, NSD was observed on 16 of 70 sides (22.9%) in the ultrasonic group and 28 of 64 sides (43.8%) in the conventional group; this difference was significant. Furthermore, recovery from NSD at 3 months after BSSO was significantly more common in the ultrasonic group than in the conventional group. In the ultrasonic group, even when the distance from the buccal aspect of the IFAN canal to the outer buccal cortical margin was shorter, NSD of the IFAN was less frequent. CONCLUSIONS: Ultrasonic surgery may be an effective technique to reduce the incidence of NSD after BSSO, and it contributed to recovery from NSD. The use of an ultrasonic device for BSSO is recommended when the distance from the buccal aspect of the IFAN canal to the outer buccal cortical margin is shorter on computed tomography.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180225
[Lr] Last revision date:180225
[St] Status:Publisher

  8 / 6113 MEDLINE  
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[PMID]: 29407507
[Au] Autor:Garib D; Yatabe M; de Souza Faco RA; Gregório L; Cevidanes L; de Clerck H
[Ad] Address:Department of Orthodontics, Bauru Dental School, Hospital of Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, São Paulo, Brazil. Electronic address: dgarib@usp.br.
[Ti] Title:Bone-anchored maxillary protraction in a patient with complete cleft lip and palate: A case report.
[So] Source:Am J Orthod Dentofacial Orthop;153(2):290-297, 2018 Feb.
[Is] ISSN:1097-6752
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Sagittal maxillary deficiency is frequently observed in patients with operated unilateral complete cleft of the lip and palate. Treatment for moderate to severe Class III malocclusion usually relies on LeFort I surgery for maxillary advancement after the end of growth. This case report describes bone-anchored maxillary protraction in a 10-year-old white boy with unilateral complete cleft of the lip and palate. His interarch relationship was diagnosed as GOSLON index 5 before treatment with a negative overjet of 3.2 mm. The orthopedic traction was started 4 months after secondary alveolar bone graft surgery and before comprehensive orthodontic treatment. Class III elastics were used full time for 18 months. After treatment, the interarch relationship was GOSLON index 1 with a positive overjet. The SNA angle increased by 6.50° and A-Na Perp increased by 3.8 mm, leading to marked improvement in facial convexity (+14.6°). No posterior rotation of the mandible occurred with a slight closure of the gonial angle. Visualization of 3-dimensional color-coded maps showed an overall forward maxillary displacement. The bone-anchored maxillary protraction results for this patient are a promising orthopedic therapy for patients with unilateral complete cleft of the lip and palate, with the advantage of achieving much earlier improvement of facial esthetics and functional occlusion, compared with LeFort I surgery at skeletal maturity.
[Mh] MeSH terms primary: Cleft Lip/therapy
Cleft Palate/therapy
Palatal Expansion Technique
[Mh] MeSH terms secundary: Child
Cleft Lip/diagnostic imaging
Cleft Palate/diagnostic imaging
Humans
Hydroxyethylrutoside
Male
Malocclusion, Angle Class III/diagnostic imaging
Malocclusion, Angle Class III/therapy
Orthodontic Anchorage Procedures/methods
Orthodontic Brackets
Radiography, Dental
Radiography, Panoramic
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Hydroxyethylrutoside)
[Em] Entry month:1802
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[Js] Journal subset:D; IM
[Da] Date of entry for processing:180207
[St] Status:MEDLINE

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[PMID]: 29407504
[Au] Autor:Maino G; Turci Y; Arreghini A; Paoletto E; Siciliani G; Lombardo L
[Ad] Address:Postgraduate School of Orthodontics, University of Ferrara, Ferrara, Italy.
[Ti] Title:Skeletal and dentoalveolar effects of hybrid rapid palatal expansion and facemask treatment in growing skeletal Class III patients.
[So] Source:Am J Orthod Dentofacial Orthop;153(2):262-268, 2018 Feb.
[Is] ISSN:1097-6752
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:INTRODUCTION: The purpose of this study was to describe the skeletal and dentoalveolar changes in a group of growing skeletal Class III patients treated with hybrid rapid palatal expansion and facemask. METHODS: Twenty-eight growing patients with skeletal Class III malocclusion were treated using a rapid maxillary expander with hybrid anchorage according to the ALT-Ramec protocol (SKAR III; E.P.), followed by 4 months of facemask therapy. Palatal miniscrew placement was accomplished via digital planning and the construction of a high-precision, individualized surgical guide. Pretreatment and posttreatment cephalometric tracings were analyzed, comparing dental and skeletal measurements. RESULTS: Point A advanced by a mean of 3.4 mm with respect to the reference plane Vert-T. The mandibular plane rotated clockwise, improving the ANB (+3.41°) and the Wits appraisal (+4.92 mm). The maxillary molar had slight extrusion (0.42 mm) and mesialization (0.87 mm). CONCLUSIONS: The use of a hybrid-anchorage expander followed by 4 months of facemask treatment improves the skeletal Class III relationship with minimal dental effects, even in older patients (mean age, 11 years 4 months, ± 2.5 years).
[Mh] MeSH terms primary: Alveolar Process/pathology
Extraoral Traction Appliances
Jaw/pathology
Malocclusion, Angle Class III/therapy
Palatal Expansion Technique
[Mh] MeSH terms secundary: Age Factors
Cephalometry
Child
Combined Modality Therapy
Cone-Beam Computed Tomography
Female
Humans
Male
Malocclusion, Angle Class III/diagnostic imaging
Malocclusion, Angle Class III/pathology
Palatal Expansion Technique/instrumentation
Radiography, Dental
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[Js] Journal subset:D; IM
[Da] Date of entry for processing:180207
[St] Status:MEDLINE

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[PMID]: 29308861
[Au] Autor:Mikovic ND; Lazarevic MM; Tatic Z; Krejovic-Trivic S; Petrovic M; Trivic A
[Ti] Title:Radiographic cephalometry analysis of condylar position after bimaxillary osteotomy in patients with mandibular prognathism.
[So] Source:Vojnosanit Pregl;73(4):318-25, 2016 Apr.
[Is] ISSN:0042-8450
[Cp] Country of publication:Serbia
[La] Language:eng
[Ab] Abstract:Background/Aim: Postoperative condylar position is a substantial concern in surgical correction of mandibular prognathism. Orthognathic surgery may change condylar position and this is considered a contributing factor for early skeletal relapse and the induction of temporomandibular disorders. The purpose of this study was to evaluate changes in condylar position, and to correlate angular skeletal measurements following bimaxillary surgery. Methods: On profile teleradiographs of 21 patients with mandibular angular and linear parametres, the changes in condylar position, were measured during preoperative orthodontic treatment and 6 months after the surgical treatment. Results: A statistically significant difference in values between the groups was found. The most distal point on the head of condyle point (DI) moved backward for 1.38 mm (p = 0.02), and the point of center of collum mandibulae point (DC) moved backward for 1.52 mm (p = 0.007). The amount of upward movement of the point DI was 1.62 mm (p = 0.04). Conclusion: In the patients with mandibular prognathism, the condyles tend to migrate upward and forward six months after bimaxillary surgery.
[Mh] MeSH terms primary: Cephalometry/methods
Malocclusion, Angle Class III/surgery
Mandibular Condyle/diagnostic imaging
Osteotomy/methods
[Mh] MeSH terms secundary: Adolescent
Adult
Female
Humans
Male
Radiography
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180213
[Lr] Last revision date:180213
[Js] Journal subset:IM
[Da] Date of entry for processing:180109
[St] Status:MEDLINE
[do] DOI:10.2298/VSP141210051M


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