Database : MEDLINE
Search on : Retroperitoneal and Fibrosis [Words]
References found : 3188 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 319 go to page                         

  1 / 3188 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29191853
[Au] Autor:Stevenson DR; Hashim H; Salman M; Mouyis M
[Ad] Address:Northwick Park Hospital, Harrow, UK danny.r.stevenson@gmail.com.
[Ti] Title:A non-cardiac cause of bilateral leg swelling.
[So] Source:BMJ;359:j5306, 2017 11 30.
[Is] ISSN:1756-1833
[Cp] Country of publication:England
[La] Language:eng
[Mh] MeSH terms primary: Edema/diagnosis
Immunoglobulin G/blood
Leg/pathology
Retroperitoneal Fibrosis/diagnostic imaging
[Mh] MeSH terms secundary: Aged
Diagnosis, Differential
Edema/drug therapy
Edema/etiology
Glucocorticoids/administration & dosage
Glucocorticoids/therapeutic use
Humans
Leg/physiopathology
Male
Prednisolone/administration & dosage
Prednisolone/therapeutic use
Retroperitoneal Fibrosis/complications
Retroperitoneal Fibrosis/drug therapy
Retroperitoneal Fibrosis/immunology
Tomography, X-Ray Computed/methods
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:0 (Glucocorticoids); 0 (Immunoglobulin G); 9PHQ9Y1OLM (Prednisolone)
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:171202
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j5306

  2 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29465558
[Au] Autor:Xiao J; Xu P; Li B; Hong T; Liu W; He X; Zheng C; Zhao Y
[Ad] Address:Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
[Ti] Title:Analysis of clinical characteristics and treatment of immunoglobulin G4-associated cholangitis: A retrospective cohort study of 39 IAC patients.
[So] Source:Medicine (Baltimore);97(8):e9767, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Immunoglobulin (Ig)G4-associated cholangitis (IAC) is one of the common organ manifestations of IgG4-related systemic disease (ISD). IAC and autoimmune pancreatitis (AIP) may mimic sclerosing cholangitis, cholangiocarcinoma, or pancreatic carcinoma. Diagnosis is based on a combination of clinical, biochemical, radiological, and histological findings.To study the clinical presentation of and treatment strategy for IAC, we reviewed clinical, serologic, and imaging characteristics, as well as treatment response, in 39 patients with IAC. The majority of patients were men (82%). Clinical features on presentation included obstructive jaundice in 26 patients (67%) and abdominal pain in 20 (51%). Positive IgG4 immunostaining was seen in 27 patients. The median serum IgG4 level before treatment was 769.4 mg/dL (range, 309.1-1229.7 mg/dL). After the steroid therapy, the median serum IgG4 level in 23 patients was 247.0 mg/dL (range, 139.0-355.0 mg/dL). Cholangiograms were available in 36 (92%) patients. Stenosis of the lower part of the common bile duct was found in 26 of 39 patients. Stenosis was diffusely distributed in the intra- and extrahepatic bile ducts in 14 of 39 patients. Additionally, strictures of the bile duct were detected in the hilar hepatic lesions in 27 of 39 patients. AIP was the most frequent comorbidity (35/39 in this study) of IAC. Other affected organs included eyes (n = 6), salivary glands (sialadenitis, n = 10), lymph nodes (mediastinal and axillary, n = 3), kidneys (n = 2), and the retroperitoneum (retroperitoneal fibrosis, n = 2).Regarding treatment, 29 patients were treated with steroids, of whom one underwent pancreatoduodenectomy, and one underwent choledochojejunostomy. Eight patients were treated with biliary stents. The remaining 19 patients took prednisolone alone. Eight patients achieved spontaneous resolution. Four patients with suspected pancreatic cancer or cholangiocarcinoma underwent surgery, including 2 patients who also received postoperative steroids. All patients were regularly followed up for 9 to 36 months. Only 2 patients in the steroids treatment group relapsed to manifest obstructive jaundice and high serum IgG4 levels. These 2 patients were treated with steroids and biliary stents, resulting in complete remission.We also review the diagnostic and therapeutic management and discuss recent pathophysiological findings, which might aid in understanding the molecular mechanisms contributing to IAC and other manifestations of IgG4-related diseases (IgG4-RD). Biomarkers that are more accurate are needed to correctly diagnose IAC and prevent misdiagnoses and unnecessary therapeutic interventions.
[Mh] MeSH terms primary: Autoimmune Diseases/immunology
Autoimmune Diseases/therapy
Cholangitis/immunology
Cholangitis/therapy
Immunoglobulin G/blood
[Mh] MeSH terms secundary: Adult
Anti-Inflammatory Agents/therapeutic use
Autoimmune Diseases/pathology
Biliary Tract Surgical Procedures/instrumentation
Biliary Tract Surgical Procedures/methods
Cholangitis/pathology
Choledochostomy
Common Bile Duct/pathology
Constriction, Pathologic
Female
Humans
Male
Middle Aged
Pancreaticoduodenectomy
Pancreatitis/immunology
Prednisolone/therapeutic use
Retrospective Studies
Stents
[Pt] Publication type:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Inflammatory Agents); 0 (Immunoglobulin G); 9PHQ9Y1OLM (Prednisolone)
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180222
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009767

  3 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29410311
[Au] Autor:Dowling CM; Assel M; Musser JE; Meeks JJ; Sjoberg DD; Bosl G; Motzer R; Bajorin D; Feldman D; Carver BS; Sheinfeld J
[Ad] Address:Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, NY.
[Ti] Title:Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen.
[So] Source:Urology;, 2018 Feb 02.
[Is] ISSN:1527-9995
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To determine the pathologic findings and clinical outcome of patients with pure embryonal carcinoma (EC) of the testis who were diagnosed with testis cancer from January 1989 to January 2013 who underwent an orchiectomy, cisplatin-based chemotherapy and a postchemotherapy retroperitoneal lymph node dissection (PC-RPLND). METHODS: We compared those patients with 100% EC with those with mixed nonseminomatous germ cell tumor pathology who underwent a PC-RPLND. RESULTS: Of 1105 patients who underwent a PC-RPLND, 145 had pure EC. Twenty-six percent of patients presented with metastatic disease outside the retroperitoneum. Patients with mixed histologies tended to have worse International Germ Cell Cancer Collaborative Group risk compared to those with EC at orchiectomy (P = .037). Histology at PC-RPLND revealed fibrosis or necrosis in 76%, mature teratoma in 19% and viable cancer in 4%. Over one-third of the patients had a residual mass of <1 cm prior to RPLND; of whom 15% harbored mature teratoma in PC-RPLND histology. The Kaplan-Meier estimated probability of recurrence at 5 years of follow-up was 3.1% (95% CI 1.2%, 8.0%) for EC histology, 7.3% lower than mixed histology. For cancer-specific mortality, the Kaplan-Meier estimated probability at 5 years was 4.6% (95% CI 3.3%, 6.3%) and 1.7% (95% CI 0.4%, 6.8%) for mixed and pure EC histologies, respectively. CONCLUSION: Approximately 20% of patients with pure EC had teratoma at PC-RPLND. We have shown that those with a maximum node size of <1 cm should not be precluded from RPLND.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180225
[Lr] Last revision date:180225
[St] Status:Publisher

  4 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29474847
[Au] Autor:Leo R; van Agthoven T; Figueiredo A; Jewett MAS; Fadaak K; Sweet J; Ahmad AE; Anson-Cartwright L; Chung P; Hansen A; Warde P; Castelo-Branco P; O'Malley M; Bedard PL; Looijenga LHJ; Hamilton RJ
[Ad] Address:Departments of Surgery (Urology) and Surgical Oncology, Princess Margaret Cancer Centre and the University Health Network, University of Toronto, Toronto, Ontario, Canada; Faculty of Medicine, University of Coimbra, Portugal.
[Ti] Title:Serum miRNA predicts viable disease post-chemotherapy in testicular non-seminoma germ cell tumor patients.
[So] Source:J Urol;, 2018 Feb 20.
[Is] ISSN:1527-3792
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Retroperitoneal lymph node dissection (RPLND) is recommended for residual masses >1cm post-chemotherapy (pc) in nonseminoma germ cell tumors (NSGCT). Currently, there is no reliable predictor for pcRPLND histology and up to 50% will harbour necrosis/fibrosis only, thus rendering a potentially morbid surgery to be of limited therapeutic value. In this study we aimed to evaluate the ability of defined serum microRNAs (miRNA) to predict residual viable NSGCT after chemotherapy. METHODS: Serum miRNA levels (miR-371a-3p, miR-373-3p and miR-367-3p) were measured using the ampTSmiR test in 82 patients (cohort A = 39, cohort B = 43) treated with orchiectomy, chemotherapy and pcRPLND. miRNA levels were compared to clinical characteristics, serum tumor markers and correlated with presence of viable germ cell tumor (GCT) vs. fibrosis/necrosis and teratoma. miRNA-discriminative capacity was determined by receiver operating characteristic (ROC) analysis. RESULTS: miRNA levels were significantly associated with extent of disease at chemotherapy and declined significantly after chemotherapy. Conventional serum tumor maker levels were uninformative post-chemotherapy. However, after chemotherapy, miRNA levels remained elevated in patients harboring viable GCT in pcRPLND specimens. miR-371a-3p demonstrated the highest discriminative capacity [area under the curve (AUC) 0.874, CI 95% 0.774 - 0.974, p<0.0001] for viable GCT. Using an adapted hypothetical cut-off (≤ 3 cm) for surgical intervention, miR-371a-3p correctly stratified all patients with viable (GCT) residual retroperitoneal lesions (p=0.02; 100% sensitivity). CONCLUSIONS: Our study demonstrates, for the first time, the potential value of miR-371a-3p to predict viable GCT in residual masses post-chemotherapy. Prospective studies are required to confirm clinical utility.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180223
[Lr] Last revision date:180223
[St] Status:Publisher

  5 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29473379
[Au] Autor:Seker KG; Eksi M; Colakoglu Y; Yenice MG; Akbay FG; Tugcu V; Simsek A
[Ad] Address:Bakirkoy Sadi Konuk Research and Training Hospital, Department of Urology, Istanbul. simsek76@yahoo.com.
[Ti] Title:A rare cause of acute post renal failure: Retroperitoneal fibrosis.
[So] Source:Arch Ital Urol Androl;89(4):301-304, 2017 Dec 31.
[Is] ISSN:1124-3562
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:Retroperitoneal fibrosis is an inflammatory process which may cause acute renal failure. In patients who admitted to emergency services with obstructive uropathy, retroperitoneal fibrosis should be considered in the differential diagnosis. We present our ten cases who admitted to emergency department with obstructive acute renal failure related to retroperitoneal fibrosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180223
[Lr] Last revision date:180223
[St] Status:In-Data-Review
[do] DOI:10.4081/aiua.2017.4.301

  6 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy

[PMID]: 29465374
[Au] Autor:Forestier A; Buob D; Mirault T; Puech P; Gnemmi V; Launay D; Hachulla E; Hatron PY; Lambert M
[Ad] Address:Department of Internal Medicine and Clinical Immunology, CHRU Lille; Centre National de Rfrence Maladies Systmiques et Auto-Immunes Rares; FHU Immune-Mediated Inflammatory Diseases and Targeted Therapies (IMMINeNT), Lille, France.
[Ti] Title:No specific imaging pattern can help differentiate IgG4-related disease from idiopathic retroperitoneal fibrosis: 18 histologically proven cases.
[So] Source:Clin Exp Rheumatol;, 2018 Feb 14.
[Is] ISSN:0392-856X
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Retroperitoneal fibrosis (RPF) is a rare disease, with unknown aetiology (idiopathic RPF: iRPF) in two-thirds of cases. A subset of iRPF may be a manifestation of IgG4-related disease (IgG4-RD). Thus, recognition of IgG4-RD-RPF is crucial to optimise patient's care with iRPF. The current study aimed to examine imaging specific patterns, which could help differentiate between IgG4-RD-RPF and iRPF, and thus skip performing biopsies. METHODS: This analysis included patients with iRPF and a retroperitoneal biopsy at the Lille University Hospital, France. We reviewed their baseline characteristics, clinical presentation, biological results and imaging features. Patients were classified in 3 groups according to histopathological characteristics of IgG4-RD as follows: highly suggestive of IgG4-RD, possible IgG4-RD, or non-evocative of IgG4-RD. RESULTS: Of the 18 patients analysed in the study, 4 (22%) patients had highly suggestive IgG4-RD-RPF, 8 (44%) possible IgG4-RD-RPF and 6 (33%) non-evocative IgG4-RD. We found no clinical, biological features nor specific imaging pattern that could help differentiate between the 3 groups. CONCLUSIONS: After ruling out all known causes of RPF, retroperitoneal biopsy is still necessary to ascertain the diagnosis of IgG4-RD-RPF. No specific pattern can be used to distinguish between IgG4-RD-RPF and iRFP.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180221
[Lr] Last revision date:180221
[St] Status:Publisher

  7 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29430718
[Au] Autor:Alobaid K; Faty M; El-Nahas A; Al-Terki A; Khan Z
[Ad] Address:Medical Laboratory Department, Microbiology Unit, Al-Amiri Hospital, Kuwait City, Kuwait.
[Ti] Title:Renal fungus ball in a patient with retroperitoneal fibrosis: Unique complication in a rare disease.
[So] Source:Mycoses;, 2018 Feb 12.
[Is] ISSN:1439-0507
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Candida fungus ball is a rare presentation of urinary tract infections among adult patients and is associated with considerable morbidity. Because clinical signs are not specific, diagnosis is often delayed. Furthermore, treatment is occasionally difficult, and the approach to such cases varies widely among different centers. In this report, we describe a patient with retroperitoneal fibrosis who developed a renal fungus ball. Management of this challenging case is discussed, and review of the literature is presented.
[Pt] Publication type:CASE REPORTS
[Em] Entry month:1802
[Cu] Class update date: 180212
[Lr] Last revision date:180212
[St] Status:Publisher
[do] DOI:10.1111/myc.12745

  8 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29423783
[Au] Autor:Oliphant H; Gouws P
[Ad] Address:The Sussex Eye Hospital, Brighton and Sussex University Hospital, Eastern Road, Brighton, BN2 5BF, UK. Huw.oliphant@bsuh.nhs.uk.
[Ti] Title:Peyronie's disease and Dupuytren's contracture secondary to topical timolol.
[So] Source:Int Ophthalmol;, 2018 Feb 08.
[Is] ISSN:1573-2630
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Topical beta-blockers are a proven and safe medication used in the treatment of glaucoma and ocular hypertension. Local and systemic side effects are, however, well documented. Systemic side effects can include severe cardio-respiratory impairment, endocrine dysfunction, as well as headache and hyper-somnolence. Disorders involving fibrosis such as Peyronie's disease, Dupuytren's contracture, and retroperitoneal fibrosis are rarely described in the literature. CASE REPORT: We describe a case of a 55-year-old male patient undergoing treatment for ocular hypertension with topical timolol 0.25% to both eyes, who subsequently developed both Peyronie's disease and Dupuytren's contracture. To our knowledge, this is the first case of Dupuytren's contracture secondary to the use of topical timolol. CONCLUSIONS: Whilst uncommon, beta-blockers are known to be associated with such fibrotic conditions and have been reported with the use of topical timolol. This case serves to increase the current understanding of this association.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[St] Status:Publisher
[do] DOI:10.1007/s10792-018-0837-y

  9 / 3188 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29232794
[Au] Autor:Iyoki T; Maehana T; Tanaka T; Yamamoto M; Takahashi H; Masumori N
[Ad] Address:The Department of Urology, Sapporo Medical University School of Medicine.
[Ti] Title:[Clinical Evaluation of Diagnostic and Treatment Protocol of Idiopathic Retroperitoneal Fibrosis Incorporating Consideration of Possible IgG4-Related Disease].
[So] Source:Hinyokika Kiyo;63(11):449-454, 2017 Nov.
[Is] ISSN:0018-1994
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:About half of idiopathic retroperitoneal fibrosis might be classified as a IgG4-related disease, a newly characterized disease that is especially known to be sensitive to steroid therapy. We developed a new protocol for diagnosis and treatment of retroperitoneal fibrosis, which included aggressive diagnosis of IgG4- related disease. We retrospectively reviewed 22 cases with idiopathic retroperitoneal fibrosis that were diagnosed and treated according to our protocol. Of them, 10 patients (45.5%) had no evidence of IgG4- related disease (non-IgG4RD group), whereas 12 patients (54.5%) were diagnosed with IgG4-related disease (IgG4RD group). All patients received steroid therapy, and 13 patients (59.1%) underwent ureteral stenting or received prednisolone (PNS). There was no severe adverse event and planned steroid therapy was completed in all patients. In principle, maintenance steroid therapy was continued after induction therapy in the IgG4RD group, whereas steroid therapy was discontinued in the non-IgG4RD group. Regression of retroperitoneal plaque was achieved in all 22 patients. Four (57.1%) out of 7 patients and 3 (50.0%) out of 6 patients achieved freedom from ureteral stent or PNS in the non-IgG4RD group and IgG4RD group, respectively. All 3 patients with PNS became catheter-free after treatment, whereas only 4 (40.0%) of the 10 patients withureteral stent could become stent-free. Steroid therapy could be discontinued in 7 patients (70.0%) in the non-IgG4RD group. The results of this study suggest that similar efficacy of steroid therapy can be expected in the non-IgG4RD group and IgG4RD group.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180208
[Lr] Last revision date:180208
[St] Status:In-Process
[do] DOI:10.14989/ActaUrolJap_63_11_449

  10 / 3188 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29269359
[Au] Autor:Hanai S; Kinjo K; Uezato M; Tokuda Y
[Ad] Address:Department of Internal Medicine, Nakagami General Hospital, Okinawa, Japan.
[Ti] Title:A disclosed diagnosis for 24 year's unknown illness.
[So] Source:BMJ Case Rep;2017, 2017 Dec 20.
[Is] ISSN:1757-790X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease (CKD), chronic pancreatitis and history of operated cholangitis, was admitted to our hospital for abdominal pain and worsening renal function. Serum levels of IgG and IgG4 were elevated. CT scan showed the characteristic findings of IgG4-related retroperitoneal fibrosis, pancreas and kidney disease. An endoscopic biopsy revealed the finding compatible with IgG4-RD. Steroid therapy led to the remission of his abdominal pain. Patients with CKD of unknown aetiology may have IgG4-RD.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171222
[Lr] Last revision date:171222
[St] Status:In-Process


page 1 of 319 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information