Database : MEDLINE
Search on : Situs and Inversus [Words]
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[PMID]: 29499701
[Au] Autor:Dai HB; Wang ZC; Feng XB; Wang G; Li WY; Hang CH; Jiang ZW
[Ad] Address:Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, No 305 East Zhongshan Road, Nanjing, 210002, China.
[Ti] Title:Case report about a successful full robotic radical gastric cancer surgery with intracorporeal robot-sewn anastomosis in a patient with situs inversus totalis and a two-and-a-half-year follow-up study.
[So] Source:World J Surg Oncol;16(1):41, 2018 Mar 02.
[Is] ISSN:1477-7819
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: During the last decade, total laparoscopic and laparoscopic-assisted distal gastrectomy for gastric cancer patients has been developed as alternatives to open resection. In recent years, this minimally invasive surgery has been extended using robotic-assisted surgery. CASE PRESENTATION: Here, we report a surgical intervention using a Da Vinci surgical robot in which a lower two-third stomach resection with subsequent Billroth II gastrojejunostomy was performed. The patient was a 53-year-old male with complete situs inversus gastric cancer who had received 2 cycles of neo-adjuvant oxaliplatin combined with S-1 medication. The operation took 3 h in total without complications. The amount of bleeding was about 50 mL, and on day 5 after the operation, the patient was discharged. CONCLUSIONS: This is the first report of a successful robot-assisted gastric cancer resection of advanced gastric cancer in a patient with the anatomical abnormality of situs inversus totalis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.1186/s12957-018-1311-z

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[PMID]: 29426764
[Au] Autor:Alami A; Kriet M; Reda K; Laktaoui A; Oubaaz A
[Ad] Address:Service d'ophtalmologie, 3(e) hôpital Militaire-de-Laâyoune, Laâyoune, Maroc. Electronic address: alami_ahmed3@hotmail.com.
[Ti] Title:Dysversion papillaire réalisant un aspect en « comète ¼. [Situs inversus of the optic disc with a "comet" appearance].
[So] Source:J Fr Ophtalmol;41(2):187-188, 2018 Feb.
[Is] ISSN:1773-0597
[Cp] Country of publication:France
[La] Language:fre
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Data-Review

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[PMID]: 29408869
[Au] Autor:Dettmer S; Ringshausen F; Vogel-Claussen J; Fuge J; Faschkami A; Shin HO; Schwerk N; Welte T; Wacker F; Rademacher J
[Ad] Address:Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
[Ti] Title:Computed tomography in adult patients with primary ciliary dyskinesia: Typical imaging findings.
[So] Source:PLoS One;13(2):e0191457, 2018.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Among patients with non-cystic fibrosis bronchiectasis, 1-18% have an underlying diagnosis of primary ciliary dyskinesia (PCD) and it is suspected that there is under-recognition of this disease. Our intention was to evaluate the specific features of PCD seen on computed tomography (CT) in the cohort of bronchiectasis in order to facilitate the diagnosis. MATERIALS AND METHODS: One hundred and twenty-one CTs performed in patients with bronchiectasis were scored for the involvement, type, and lobar distribution of bronchiectasis, bronchial dilatation, and bronchial wall thickening. Later, associated findings such as mucus plugging, tree in bud, consolidations, ground glass opacities, interlobular thickening, intralobular lines, situs inversus, emphysema, mosaic attenuation, and atelectasis were registered. Patients with PCD (n = 46) were compared to patients with other underlying diseases (n = 75). RESULTS: In patients with PCD, the extent and severity of the bronchiectasis and bronchial wall thickness were significantly lower in the upper lung lobes (p<0.001-p = 0.011). The lobar distribution differed significantly with a predominance in the middle and lower lobes in patients with PCD (<0.001). Significantly more common in patients with PCD were mucous plugging (p = 0.001), tree in bud (p <0.001), atelectasis (p = 0.009), and a history of resection of a middle or lower lobe (p = 0.047). Less common were emphysematous (p = 0.003) and fibrotic (p<0.001) changes. A situs inversus (Kartagener's Syndrome) was only seen in patients with PCD (17%, p <0.001). CONCLUSION: Typical imaging features in PCD include a predominance of bronchiectasis in the middle and lower lobes, severe tree in bud pattern, mucous plugging, and atelectasis. These findings may help practitioners to identify patients with bronchiectasis in whom further work-up for PCD is called for.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:In-Process
[do] DOI:10.1371/journal.pone.0191457

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[PMID]: 29390355
[Au] Autor:Zhu C; Huang S; Zhou C; Yang X; Wang L; Ling T; Liu L; Song Y
[Ad] Address:Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
[Ti] Title:A case report of congenital scoliosis associated with situs inversus totalis.
[So] Source:Medicine (Baltimore);96(50):e9239, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Situs inversus totalis is a rare anomaly disease in which the organs in the chest and abdomen are positioned in a mirror image reversal of normal positions. Although this has been confirmed to be associated with spinal abnormalities, reports about situs inversus totalis with congenital scoliosis remain limited. PATIENT CONCERNS: We present a 9-year-old girl having congenital scoliosis associated with situs inversus totalis. DIAGNOSES: She also had other associated anomalies: ventricular septal defect, mild restrictive ventilatory dysfunction, hydronephrosis, and syringomyelia. Her preoperative Cobb angle (T11-L3) was 78°. INTERVENTIONS: She received single growing rods treatment and subsequent posterior spinal fusion correction surgery for her scoliosis. OUTCOMES: The coronal Cobb angle of the main curve was corrected to 20° postoperatively and no obvious loss of spinal corrective angle was identified 1 year after the correction surgery. LESSONS: Growing rods technique could be a safe and effective alternative for the treatment of scoliosis associated with situs inversus totalis. In the correction of left-sided lumbar curve of this kind of patients, the risks of aorta impingements should not be neglected when placing pedicle screws on the concave sides.
[Mh] MeSH terms primary: Scoliosis/congenital
Scoliosis/surgery
Situs Inversus
[Mh] MeSH terms secundary: Abnormalities, Multiple
Child
Female
Humans
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180301
[Lr] Last revision date:180301
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009239

  5 / 2932 MEDLINE  
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[PMID]: 29481728
[Au] Autor:Martens HA; Boks SS
[Ad] Address:department of Rheumatology.
[Ti] Title:Diffuse idiopathic skeletal hyperostosis; on the wrong side?
[So] Source:Arthritis Rheumatol;, 2018 Feb 26.
[Is] ISSN:2326-5205
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A 58-year old man was referred to our rheumatology department because of arthralgia and generalized stiffness. His was already known with Kartagener syndrome with situs inversus. Physical examination revealed multiple painful enthesis and stiffness of the thoracic spine. There were no signs of arthritis. Diffuse idiopathic skeletal hyperostosis (DISH) was suspected. An x-ray of the thoracic spine revealed continuous ossification between five contiguous vertebral bodies (A). The lateral view showed extensive ossification of the anterior longitudinal ligament (B). The diagnosis of DISH was made. In DISH, the ossification is normally localized on the right side of the spine. It is hypothesized that the descending aorta inhibits ossification on the left side. In our patient, however, the ossification occurred on the left side. We concluded that along with the situs inversus due to Kartagener syndrome, the pathologic features of DISH had also "moved" to the contralateral side. This feature has rarely been reported in patients with DISH. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:Publisher
[do] DOI:10.1002/art.40465

  6 / 2932 MEDLINE  
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[PMID]: 29338299
[Au] Autor:García Vieites M; Martinez-Sapiña Llanas MJ; Gómez Zincke M; Bouzas Zubeldía B; Bautista-Hernandez V
[Ad] Address:1 Department of Cardiovascular Surgery, 16811 Coruna University Hospital , Coruna, Spain.
[Ti] Title:Mitral valve replacement via a left thoracotomy in dextrocardia and situs solitus.
[So] Source:Asian Cardiovasc Thorac Ann;26(2):142-145, 2018 Feb.
[Is] ISSN:1816-5370
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Dextrocardia with situs solitus and severe mitral regurgitation is a rare clinical presentation which posse a surgical challenge and requires specific preoperative planning. A 54-year-old women with this anatomy, multiple thoracic procedures, and severe mitral valve regurgitation underwent successful mitral valve replacement with a 27-mm mechanical prosthesis through a left thoracotomy under ventricular fibrillation, on the basis of computed tomography findings. We emphasize the importance of preoperative planning and a surgical approach through a left thoracotomy and under ventricular fibrillation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180224
[Lr] Last revision date:180224
[St] Status:In-Process
[do] DOI:10.1177/0218492318755180

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[PMID]: 29461344
[Au] Autor:Sebro R
[Ad] Address:From the Departments of Radiology, Genetics, and Orthopedic Surgery, University of Pennsylvania, Philadelphia, PA.
[Ti] Title:Confirmation of the Influence of Descending Aorta on Osteophyte Formation in Dish.
[So] Source:J Clin Rheumatol;, 2018 Feb 14.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND/OBJECTIVE: The aim of the study was to determine whether the location of the bridging thoracic osteophytes is related to the location of the descending thoracic aorta in patients with diffuse idiopathic skeletal hyperostosis (DISH). METHODS: This is a retrospective matched case-control study on patients treated between 2001 and 2016 at a single institution. Patients with DISH and situs inversus totalis were compared with patients with DISH and situs solitus, using 1:1 age and sex matching. Patients were diagnosed as having DISH based on Resnick and Niwayama criteria. Patients with scoliosis were excluded from the analysis. The patients' bridging thoracic osteophytes were divided into 3 categories: both (bilateral bridging thoracic osteophytes spanning at least 4 levels), left (left bridging thoracic osteophytes spanning at least 4 levels), or right (right bridging thoracic osteophytes spanning at least 4 levels). Mantel-Haenzel matched-pairs analyses were performed to assess any association. RESULTS: Approximately 87.5% (7/8) and 12.5% (1/8) of patients with situs inversus totalis had left and bilateral anterior bridging osteophytes, respectively. However, 0% (0/8) and 25.0% (2/8) of patients with situs solitus had left and bilateral anterior bridging osteophytes, respectively. The bridging thoracic spine osteophyte location was statistically significantly associated with the location of the descending thoracic aorta (odds ratio, >1.34; χ3 = 8; P = 0.046). CONCLUSIONS: The location of the descending thoracic aorta is associated with the location of DISH osteophytes and supports the biomechanical hypothesis that aortic pulsations affect osteophyte location.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[St] Status:Publisher
[do] DOI:10.1097/RHU.0000000000000698

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[PMID]: 29460885
[Au] Autor:Istomin AG; Muravyova EG; Barykov VN; Shestopalov SS; Sarsenbaev BK; Kyrchanov VI
[Ad] Address:Department of Hospital Surgery of South Ural State Medical University, Chelyabinsk Regional Clinical Hospital, Chelyabinsk, Russia.
[Ti] Title:Punktsionnoe drenirovanie abstsessa pecheni pri transpozitsii vnutrennikh organov. [Percutaneous drainage of liver abscess in case of situs viscerus inversus].
[So] Source:Khirurgiia (Mosk);(2):85-86, 2018.
[Is] ISSN:0023-1207
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[St] Status:In-Data-Review
[do] DOI:10.17116/hirurgia2018285-86

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[PMID]: 29455821
[Au] Autor:Maddali MM; Al-Maskari SN; Kandachar PS; Lacour-Gayet F
[Ad] Address:Department of Cardiac Anesthesia, National Heart Center, Royal Hospital, Muscat, Oman. Electronic address: madanmaddali@hotmail.com.
[Ti] Title:Pulmonary Hemorrhage After Arterial Switch Operation.
[So] Source:Ann Thorac Surg;105(3):e113-e115, 2018 Mar.
[Is] ISSN:1552-6259
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Major aortopulmonary collateral arteries can influence the postoperative course of arterial switch operation, with heart failure being the common clinical presentation. A relatively rare presentation of an aortopulmonary collateral artery in the form of persistent postoperative pulmonary hemorrhage was encountered after an uneventful arterial switch operation in a neonate with transposition of the great arteries, intact interventricular septum, and situs inversus totalis. The aortopulmonary collateral artery was coil embolized with a successful outcome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180219
[Lr] Last revision date:180219
[St] Status:In-Data-Review

  10 / 2932 MEDLINE  
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[PMID]: 29365104
[Au] Autor:Lorès P; Coutton C; El Khouri E; Stouvenel L; Givelet M; Thomas L; Rode B; Schmitt A; Louis B; Sakheli Z; Chaudhry M; Fernandez-Gonzales A; Mitsialis A; Dacheux D; Wolf JP; Papon JF; Gacon G; Escudier E; Arnoult C; Bonhivers M; Savinov SN; Amselem S; Ray PF; Dulioust E; Touré A
[Ad] Address:INSERM U1016, Institut Cochin, Paris 75014, France.
[Ti] Title:Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia.
[So] Source:Hum Mol Genet;, 2018 Jan 22.
[Is] ISSN:1460-2083
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Motile cilia and sperm flagella share an extremely conserved microtubule-based cytoskeleton, called the axoneme, which sustains beating and motility of both organelles. Ultra-structural and/or functional defects of this axoneme are well-known to cause primary ciliary dyskinesia (PCD), a disorder characterized by recurrent respiratory tract infections, chronic otitis media, situs inversus, male infertility and in most severe cases, hydrocephalus. Only recently, mutations in genes encoding axonemal proteins with preferential expression in the testis were identified in isolated male infertility; in those cases, individuals displayed severe asthenozoospermia due to Multiple Morphological Abnormalities of the sperm Flagella (MMAF) but not PCD features. In this study, we performed genetic investigation of two siblings presenting MMAF without any respiratory PCD features, and we report the identification of the c.2018T > G (p.Leu673Pro) transversion in AK7, encoding an adenylate kinase, expressed in ciliated tissues and testis. By performing transcript and protein analyses of biological samples from individual carrying the transversion, we demonstrate that this mutation leads to the loss of AK7 protein in sperm cells but not in respiratory ciliated cells, although both cell types carry the mutated transcript and no tissue-specific isoforms were detected. This work therefore, supports the notion that proteins shared by both cilia and sperm flagella may have specific properties and/or function in each organelle, in line with the differences in their mode of assembly and organization. Overall, this work identifies a novel genetic cause of asthenozoospermia due to MMAF and suggests that in humans, more deleterious mutations of AK7 might induce PCD.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180214
[Lr] Last revision date:180214
[St] Status:Publisher
[do] DOI:10.1093/hmg/ddy034


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