Database : MEDLINE
Search on : Striae and Distensae [Words]
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[PMID]: 29498185
[Au] Autor:Kasielska-Trojan A; Pietrusinski M; Borowiec M; Antoszewski B
[Ad] Address:Plastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, Lódz, Poland.
[Ti] Title:Collagen type III and elastin genes polymorphism and the risk of nonsyndromic striae.
[So] Source:J Cosmet Dermatol;, 2018 Mar 01.
[Is] ISSN:1473-2165
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Striae have been reported to be one of the most common skin lesions and a commonly encountered esthetic problem. OBJECTIVES: The aim of this research was to examine elastin gene polymorphism (rs7787362, ELN) and collagen type III alpha 1 polymorphism (rs1800255, COL3A1) among polish woman population with SD in comparison with women without the lesions and to verify these polymorphisms as risk factors for SD. METHODS: Seventy female students (35 with striae (the mean age 23.9 years, SD 1.2 years) and 35 without these lesions (22.9 years, SD 1.7 years)) were included in the study. The subjects were asked to fill out a questionnaire including questions concerning risk factors for SD and had a cheek swabbed for cells for DNA isolation. RESULTS: Analysis of polymorphisms of elastin gene (rs7787362) and COL3A1 gene (rs1800255) showed that women with SD and without these lesions did not differ in these aspects. Polymorphism rs7787362 was also analyzed in relation to SD in different locations, and showed no differences. CONCLUSION: In conclusion, we found that there are some clinical factors that reduced the risk of SD: history of intended weight loss, negative family history of SD, and lower BMI. Gene polymorphisms analysis in patients with SD may help to establish the etiology of these lesions and to target the therapy. Analysis of polymorphisms of elastin gene (rs7787362) did not show differences in allele distribution between women with and without SD. Polymorphisms of COL3A1 gene (rs1800255) also did not differ between the examined groups.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180302
[Lr] Last revision date:180302
[St] Status:Publisher
[do] DOI:10.1111/jocd.12522

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[PMID]: 29451986
[Au] Autor:Forbat E; Al-Niaimi F
[Ad] Address:a Department of General medicine, Chelsea and Westminster Hospital , London , UK.
[Ti] Title:Treatment of striae distensae: An evidence-based approach.
[So] Source:J Cosmet Laser Ther;:1-9, 2018 Feb 16.
[Is] ISSN:1476-4180
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Striae distensae (SD), otherwise known as "stretchmarks," are a common presenting complaint, particularly in young healthy women. SD are hypothesized to form in a patient when the cross-linked collagen is "overstretched" and rupture of this collagen matrix causes the striae. Thus, many treatments work by increasing collagen synthesis. This review critically appraises the evidence to date for the treatment of SD, including both energy-based devices and topical treatments.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180216
[Lr] Last revision date:180216
[St] Status:Publisher
[do] DOI:10.1080/14764172.2017.1418515

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[PMID]: 29316152
[Au] Autor:Hodeib AA; Hassan GFR; Ragab MNM; Hasby EA
[Ad] Address:Dermatology and Venereology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
[Ti] Title:Clinical and immunohistochemical comparative study of the efficacy of carboxytherapy vs platelet-rich plasma in treatment of stretch marks.
[So] Source:J Cosmet Dermatol;, 2018 Jan 07.
[Is] ISSN:1473-2165
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Striae distensae are dermal scars with a linear atrophic depression. The exact origin of striae distensae remains unrevealed, but low expression of collagen and fibronectin genes in the affected tissue was found. Several treatment modalities have been proposed, yet no consistent modality is available. AIM OF THE WORK: To evaluate and compare the efficacy and safety of carboxytherapy vs platelet-rich plasma (PRP) in treatment of stretch marks. PATIENTS AND METHODS: This study included 20 patients with striae alba. Every patient received treatment in the form of PRP injection in their right side (group A) and carboxytherapy session in their left side (group B) every 3-4 weeks for 4 sessions. Skin biopsies were taken before and after treatment, and they were subjected to fibronectin immunohistochemical stain. RESULTS: There was a significant improvement in striae alba in both groups after than before treatment. There was no significant difference between both groups as regards either percentage of improvement, response (grading scale), or patient satisfaction. The fibronectin-stained area was significantly higher in both groups after than before treatment, and it was significantly higher after treatment in group (B) than group (A). CONCLUSIONS: Both methods were safe and effective with minimal side effects. There was no significant difference between both methods of treatments. This was confirmed histopathologically by fibronectin expression which is found to be low in striae and increased significantly after treatment. But fibronectin expression was higher in group (B) than (A).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180109
[Lr] Last revision date:180109
[St] Status:Publisher
[do] DOI:10.1111/jocd.12481

  4 / 288 MEDLINE  
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[PMID]: 29308552
[Au] Autor:Lung PW; Tippavajhala VK; de Oliveira Mendes T; Téllez-Soto CA; Schuck DC; Brohem CA; Lorencini M; Martin AA
[Ad] Address:Institute of Research and Development (IP&D), Universidade do Vale do Paraiba (UNIVAP), Av. Shishima Hifumi, 2911, Urbanova, São José dos Campos, SP, CEP: 12244-000, Brazil.
[Ti] Title:In vivo study of dermal collagen of striae distensae by confocal Raman spectroscopy.
[So] Source:Lasers Med Sci;, 2018 Jan 07.
[Is] ISSN:1435-604X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:This research work mainly deals with studying qualitatively the changes in the dermal collagen of two forms of striae distensae (SD) namely striae rubrae (SR) and striae albae (SA) when compared to normal skin (NS) using confocal Raman spectroscopy. The methodology includes an in vivo human skin study for the comparison of confocal Raman spectra of dermis region of SR, SA, and NS by supervised multivariate analysis using partial least squares discriminant analysis (PLS-DA) to determine qualitatively the changes in dermal collagen. These groups are further analyzed for the extent of hydration of dermal collagen by studying the changes in the water content bound to it. PLS-DA score plot showed good separation of the confocal Raman spectra of dermis region into SR, SA, and NS data groups. Further analysis using loading plot and S-plot indicated the participation of various components of dermal collagen in the separation of these groups. Bound water content analysis showed that the extent of hydration of collagen is more in SD when compared to NS. Based on the results obtained, this study confirms the active involvement of dermal collagen in the formation of SD. It also emphasizes the need to study quantitatively the role of these various biochemical changes in the dermal collagen responsible for the variance between SR, SA, and NS.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180108
[Lr] Last revision date:180108
[St] Status:Publisher
[do] DOI:10.1007/s10103-017-2431-3

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[PMID]: 29277729
[Au] Autor:Crocco EI; Muzy G; Schowe NM; Albuquerque MS; Barros MD; Buck HS
[Ad] Address:Dermatology Clinic, Department of Internal Medicine, Santa Casa de Sao Paulo School of Medical Sciences. Electronic address: elisete@elisetecrocco.com.br.
[Ti] Title:Fractional ablative carbon-dioxide laser treatment improves histological and clinical aspects of striae gravidarum: a prospective open label paired study.
[So] Source:J Am Acad Dermatol;, 2017 Dec 22.
[Is] ISSN:1097-6787
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171226
[Lr] Last revision date:171226
[St] Status:Publisher

  6 / 288 MEDLINE  
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[PMID]: 29214715
[Au] Autor:Podgórna K; Kolodziejczak A; Rotsztejn H
[Ad] Address:Chair of Cosmetology, Faculty of Pharmacy, Department of Cosmetology and Aesthetic Dermatology, Medical University of Lódz, Lódz, Poland.
[Ti] Title:Cutometric assessment of elasticity of skin with striae distensae following carboxytherapy.
[So] Source:J Cosmet Dermatol;, 2017 Dec 06.
[Is] ISSN:1473-2165
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The aim of the study was to evaluate the effectiveness of carboxytherapy in the treatment of striae distensae. Additionally, discomfort and side effects associated with the treatment were assessed. MATERIALS AND METHODS: This study involved 15 women aged 22-40 years. They underwent 3 sessions of carboxytherapy at one-week intervals. Treatment was performed in skin area within stretch marks located on stomach, buttocks, and thighs. Cutometric probe was used to evaluate skin elasticity. Four measurements were performed-immediately before each treatment and one month after the last session. Photographic documentation was made before and after a series of treatment to perform clinical evaluation of changes in skin condition. RESULTS: Statistical analysis of results obtained with the use of Cutometer (R2 and R8 parameters) demonstrated that carboxytherapy significantly improved skin elasticity within stretch marks (P < .05). The analysis of photographic documentation revealed 58% improvement in stretch mark visibility. The width and length of stretch marks decreased, and their color became more like the natural color of the skin. Carboxytherapy is associated with moderate pain/discomfort. The occurrence of hematoma is the main side effect of this procedure. CONCLUSIONS: Carboxytherapy seems to be an effective method of reducing stretch marks. This procedure is safe, and it can be performed without the risk of complications. Moreover, it does not require special postoperative convalescence. Photographic documentation is a method of assessment of aesthetic procedures effectiveness, which is complementary to other objective methods (eg, the use of MPA probes).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171207
[Lr] Last revision date:171207
[St] Status:Publisher
[do] DOI:10.1111/jocd.12465

  7 / 288 MEDLINE  
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[PMID]: 29159996
[Au] Autor:Boozalis E; Grossberg AL; Puttgen KB; Heath CR; Cohen BA
[Ad] Address:Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
[Ti] Title:Demographic characteristics of teenage boys with horizontal striae distensae of the lower back.
[So] Source:Pediatr Dermatol;, 2017 Nov 21.
[Is] ISSN:1525-1470
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: This study examines the clinical characteristics and demographics of teenage boys with horizontal striae distensae of the lower back in an outpatient setting. METHODS: Retrospective medical chart reviews and telephone survey studies were completed on an outpatient cohort of 12 boys 11 to 17 years of age with a clinical diagnosis of transverse striae distensae of the lower back at a single-center, university-based, pediatric dermatology practice. We evaluated the clinical features of the striae, participant demographic characteristics, and past medical history. A review of the literature concerning risk factors was conducted using PubMed and Google Scholar. RESULTS: Of the 14 patients we contacted, 12 agreed to participate. The average age of onset for the striae was 14.3 years. All boys were above the 50th percentile in height at the time of onset. Eight (66.7%) reported a significant growth spurt before the appearance of the stretch marks. Most were asymptomatic. None of the boys had a history of unmonitored exogenous steroid use or prior infection with Bartonella henselae or Borrelia burgdorferi. Only one (8.3%) had a chronic medical condition. Eleven (91.7%) had at least one first-degree relative with striae distensae. CONCLUSION: Our results indicate that horizontal striae distensae of the lower back in adolescent boys is associated with a rapid growth spurt, tall stature, and family history of striae distensae. There is no association between this type of striae distensae and any chronic medical condition, bacterial infection, or exogenous steroid use. Thus a careful review of systems and counseling without further medical testing is reasonable management.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171121
[Lr] Last revision date:171121
[St] Status:Publisher
[do] DOI:10.1111/pde.13329

  8 / 288 MEDLINE  
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[PMID]: 29140866
[Au] Autor:Park KK; Roberts E; Tung RC
[Ad] Address:Pinnacle Dermatology, Joliet, Illinois Dermatology Section, Edward Hines Jr. VA Hospital, Hines, Illinois Department of Dermatology, Mayo Clinic, Rochester, Minnesota Division of Dermatology, Loyola University, Maywood, Illinois.
[Ti] Title:One Thousand Five Hundred Fifty Nanometer Erbium-Doped Nonablative Fractional Laser for the Treatment of Striae Distensae in Patients of Skin of Color (Fitzpatrick Skin Types IV-VI).
[So] Source:Dermatol Surg;, 2017 Nov 14.
[Is] ISSN:1524-4725
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171115
[Lr] Last revision date:171115
[St] Status:Publisher
[do] DOI:10.1097/DSS.0000000000001411

  9 / 288 MEDLINE  
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[PMID]: 29105985
[Au] Autor:Kasielska-Trojan A; Antoszewski B
[Ad] Address:Plastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, Lodz, Poland.
[Ti] Title:Do body build and composition influence striae distensae occurrence and visibility in women?
[So] Source:J Cosmet Dermatol;, 2017 Nov 06.
[Is] ISSN:1473-2165
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Striae have been reported to be one of the most common skin changes and a commonly encountered esthetic problem. OBJECTIVES: To analyze risk factors of striae not associated with pregnancy and verify if body build and composition influence striae distensae (SD) occurrence and visibility. METHODS: Eighty female students (40 with striae (the mean age 23.9 years, SD 2.05 years) and 40 without these lesions (24.7 years, SD 6.2 years)) were included in the study. The subjects were asked to fill out a questionnaire including questions concerning risk factors of SD. Body build and composition were examined using Tanita SC-331S Body Composition Analyzer. RESULTS: Women without striae more often reported a history of intended weight loss (P < .0001), less frequently had a history of contraceptives intake (P < .001) and more often their family history of striae was negative or unknown (P = .01). Multivariate analysis including body build and composition parameters indicated BMI as risk factor of SD (P = .021; OR =1.155, 95% CI 1.006; 1.325). CONCLUSIONS: History of contraceptives intake and a family history of striae are risk factors of SD occurrence, while weight loss can reduce the risk of these lesions. BMI appeared to be the risk factor of striae visibility, especially in abdomen, but not on the buttocks. Further clinical researches are needed to examine the pathophysiology of this condition and to inform patients about the possibility to reduce the risk of striae occurrence.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171106
[Lr] Last revision date:171106
[St] Status:Publisher
[do] DOI:10.1111/jocd.12455

  10 / 288 MEDLINE  
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[PMID]: 28980136
[Au] Autor:Guida S; Galimberti MG; Bencini M; Pellacani G; Bencini PL
[Ad] Address:Dermatology Unit, University of Modena and Reggio Emilia, Via del Pozzo, 71, Modena, Italy. drstefaniaguida@gmail.com.
[Ti] Title:Treatment of striae distensae with non-ablative fractional laser: clinical and in vivo microscopic documentation of treatment efficacy.
[So] Source:Lasers Med Sci;, 2017 Oct 04.
[Is] ISSN:1435-604X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The efficacy of NAFL in the treatment of striae distensae (SD) has been demonstrated. Nevertheless, the base for this improvement has not been clarified yet. The aim of this study is to describe in vivo variations occurring in the skin after the treatment, using reflectance confocal microscopy (RCM). Ten patients asking for the treatment of SD were enrolled. Clinical and RCM images were acquired before the treatment, immediately after 1 and 6 months after the first treatment. One thousand five hundred forty-nanometer laser treatments were performed every 4 weeks for 6 sessions. Efficacy was estimated through the evaluation of pre- and post-treatment clinical pictures by two expert and independent physicians and with GAIS. Improvement of SD was observed in 80% of patients. Temporary erythema and edema were reported. RCM revealed the dissolution of collagen bundles and the appearance of new papillae, as compared to baseline. NAFL represents an effective and safe treatment modality for SD. We report herein in vivo variations occurring in SD after NAFL treatment.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171005
[Lr] Last revision date:171005
[St] Status:Publisher
[do] DOI:10.1007/s10103-017-2341-4


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