Database : MEDLINE
Search on : Synkinesis [Words]
References found : 648 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 65 go to page                         

  1 / 648 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29514718
[Au] Autor:Mendez A; Hopkins A; Biron VL; Seikaly H; Zhu LF; Côté DWJ
[Ad] Address:Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, University of Alberta, Edmonton, AB, Canada. amendez@ualberta.ca.
[Ti] Title:Brief electrical stimulation and synkinesis after facial nerve crush injury: a randomized prospective animal study.
[So] Source:J Otolaryngol Head Neck Surg;47(1):20, 2018 Mar 07.
[Is] ISSN:1916-0216
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Recent studies have examined the effects of brief electrical stimulation (BES) on nerve regeneration, with some suggesting that BES accelerates facial nerve recovery. However, the facial nerve outcome measurement in these studies has not been precise or accurate. Furthermore, no previous studies have been able to demonstrate the effect of BES on synkinesis. The objective of this study is to examine the effect of brief electrical stimulation (BES) on facial nerve function and synkinesis in a rat model. METHODS: Four groups of six rats underwent a facial nerve injury procedure. Group 1 and 2 underwent a crush injury at the main trunk of the nerve, with group 2 additionally receiving BES for 1 h. Group 3 and 4 underwent a transection injury at the main trunk, with group 4 additionally receiving BES for 1 h. A laser curtain model was used to measure amplitude of whisking at 2, 4, and 6 weeks. Fluorogold and fluororuby neurotracers were additionally injected into each facial nerve to measure synkinesis. Buccal and marginal mandibular branches of the facial nerve were each injected with different neurotracers at 3 months following injury. Based on facial nucleus motoneuron labelling of untreated rats, comparison was made to post-treatment animals to deduce whether synkinesis had taken place. All animals underwent trans-cardiac perfusion with subsequent neural tissue sectioning. RESULTS: At week two, the amplitude observed for group 1 and 2 was 14.4 and 24.0 degrees, respectively (p = 0.0004). Group 4 also demonstrated improved whisking compared to group 3. Fluorescent neuroimaging labelling appear to confirm improved pathway specific regeneration with BES following facial nerve injury. CONCLUSIONS: This is the first study to use an implantable stimulator for serial BES following a crush injury in a validated animal model. Results suggest performing BES after facial nerve injury is associated with accelerated facial nerve function and improved facial nerve specific pathway regeneration in a rat model.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.1186/s40463-018-0264-0

  2 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29510722
[Au] Autor:Topçu Ç; Uysal H; Özkan Ö; Özkan Ö; Polat Ö; Bedeloglu M; Akgül A; Döger EN; Sever R; Çolak ÖH
[Ad] Address:Faculty of Engineering, Department of Electrical-Electronics Engineering, Akdeniz University, Dumlupinar Bulv. 07058 Campus, Antalya, Turkey. cagdas.topcu@medunigraz.at.
[Ti] Title:Recovery of facial expressions using functional electrical stimulation after full-face transplantation.
[So] Source:J Neuroeng Rehabil;15(1):15, 2018 Mar 06.
[Is] ISSN:1743-0003
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: We assessed the recovery of 2 face transplantation patients with measures of complexity during neuromuscular rehabilitation. Cognitive rehabilitation methods and functional electrical stimulation were used to improve facial emotional expressions of full-face transplantation patients for 5 months. Rehabilitation and analyses were conducted at approximately 3 years after full facial transplantation in the patient group. We report complexity analysis of surface electromyography signals of these two patients in comparison to the results of 10 healthy individuals. METHODS: Facial surface electromyography data were collected during 6 basic emotional expressions and 4 primary facial movements from 2 full-face transplantation patients and 10 healthy individuals to determine a strategy of functional electrical stimulation and understand the mechanisms of rehabilitation. A new personalized rehabilitation technique was developed using the wavelet packet method. Rehabilitation sessions were applied twice a month for 5 months. Subsequently, motor and functional progress was assessed by comparing the fuzzy entropy of surface electromyography data against the results obtained from patients before rehabilitation and the mean results obtained from 10 healthy subjects. RESULTS: At the end of personalized rehabilitation, the patient group showed improvements in their facial symmetry and their ability to perform basic facial expressions and primary facial movements. Similarity in the pattern of fuzzy entropy for facial expressions between the patient group and healthy individuals increased. Synkinesis was detected during primary facial movements in the patient group, and one patient showed synkinesis during the happiness expression. Synkinesis in the lower face region of one of the patients was eliminated for the lid tightening movement. CONCLUSIONS: The recovery of emotional expressions after personalized rehabilitation was satisfactory to the patients. The assessment with complexity analysis of sEMG data can be used for developing new neurorehabilitation techniques and detecting synkinesis after full-face transplantation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Data-Review
[do] DOI:10.1186/s12984-018-0356-0

  3 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29260776
[Au] Autor:Reshetov IV; Polunin GV; Ananichuk AV; Ippolitov LI; Kovalenko AA
[Ad] Address:I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russia, 119991.
[Ti] Title:Vozmozhnosti vosstanovleniia funktsii gortani: sovremennyi podkhod. [The possibilities for the restoration of the laryngeal function: the current state-of-the-art].
[So] Source:Vestn Otorinolaringol;82(6):18-23, 2017.
[Is] ISSN:0042-4668
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:The restoration of the functional competence of the larynx following bilateral laryngeal nerve damage and vocal fold paralysis is a serious challenge for the surgeon that has thus far no satisfactory solution. Physiological re-innervation that occurs naturally with time is non-selective and, in the majority of the cases, leads to synkinesis. Laryngeal pacing achieved with the application of the implantable microchips appears to be a promising approach. The animal experiments have demonstrated the possibility of successful restoration of all the functions of the larynx by means of laryngeal pacing but simultaneously revealed a number of technical issues that have to be addressed if the further progress in this field is to be achieved including the choice of the proper materials for implantation, solution of problems pertaining to the neuromuscular mapping during pacer implantation, etc.). The results of the first prospective clinical trial involving the human patients gave evidence suggesting that the laryngeal electrostimulation technology is both safe and efficient. Nevertheless, further investigations and modification of the method are needed before it can be recommended for the wider application in the routine clinical practice.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.17116/otorino201782618-23

  4 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29390531
[Au] Autor:Tu Y; Gao F
[Ad] Address:Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China.
[Ti] Title:Dexmedetomidine-based monitored conscious sedation combined local anesthesia for levator resection in a 10-year-old child with Marcus Gunn jaw-winking synkinesis: A case report.
[So] Source:Medicine (Baltimore);96(51):e9369, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Levator resection has become a routine procedure for patients with severe Marcus Gunn jaw-winking synkinesis (MGJWS). To optimize the surgical outcome, adult patients need to be kept awake, or easily aroused and responsive to verbal commands during the operation. However, levator resection is commonly performed under general anesthesia in pediatric patients. In the present case, we described a successful anesthetic protocol of conscious sedation with local anesthesia for levator resection in a child. PATIENT CONCERNS: A 10-year-old boy with MGJWS was admitted to our hospital and scheduled for levator resection. The patient was born through a normal delivery and had no previous history of allergy, no comorbidity, and no history of receiving anesthesia or operation. The laboratory tests of the patient were unremarkable. DIAGNOSES: The diagnosis of MGJWS was made by two experienced ophthalmologists. INTERVENTIONS: A 10-year-old boy with MGJWS was admitted to our hospital and scheduled for levator resection. The levator resection was performed under monitored conscious sedation with dexmedetomidine and local anesthesia. OUTCOMES: Patient with spontaneous breathing responded normally to verbal commands throughout the operation, and no adverse events occurred. The patient and ophthalmologist reported high satisfaction with anesthesia management. LESSONS: Dexmedetomidine-based monitored conscious sedation with local anesthesia is a feasible alternative to general anesthesia for levator resection in collaborative patients.
[Mh] MeSH terms primary: Blepharoptosis/diagnosis
Blepharoptosis/therapy
Dexmedetomidine/administration & dosage
Heart Defects, Congenital/diagnosis
Heart Defects, Congenital/therapy
Jaw Abnormalities/diagnosis
Jaw Abnormalities/therapy
Monitoring, Physiologic/methods
Nervous System Diseases/diagnosis
Nervous System Diseases/therapy
Oculomotor Muscles/surgery
[Mh] MeSH terms secundary: Anesthesia, Local
Child
Conscious Sedation/methods
Follow-Up Studies
Humans
Male
Rare Diseases
Reflex, Abnormal
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Nm] Name of substance:67VB76HONO (Dexmedetomidine)
[Em] Entry month:1802
[Cu] Class update date: 180219
[Lr] Last revision date:180219
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009369

  5 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29355973
[Au] Autor:Lin RJ; Smith LJ; Munin MC; Sridharan S; Rosen CA
[Ad] Address:Department of Otolaryngology-Head and Neck Surgery, University of Toronto, St. Michael's Hospital, Toronto, Ontario, Canada.
[Ti] Title:Innervation status in chronic vocal fold paralysis and implications for laryngeal reinnervation.
[So] Source:Laryngoscope;, 2018 Jan 22.
[Is] ISSN:1531-4995
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Treatment options for symptomatic unilateral vocal fold paralysis (VFP) include vocal fold augmentation, laryngeal framework surgery, and laryngeal reinnervation. Laryngeal reinnervation (LR) has been suggested to provide "tone" to the paralyzed VF. This implies a loss of tone as a result of denervation without reinnervation. We performed laryngeal electromyography (LEMG) in patients with chronic VFP to understand the innervation status associated with a chronically paralyzed vocal fold. STUDY DESIGN: Retrospective review of LEMG data in adult patients with chronic VFP from January 2009 to December 2014. METHODS: LEMG was performed at least 6 months after-onset of VFP. Qualitative LEMG, quantitative LEMG, and adductory synkinesis testing were performed, and the parameters were collected. RESULTS: Twenty-seven vocal folds were studied (23 unilateral VFP and 2 bilateral VFP). Average age was 59 ± 17 years. The median duration from recurrent laryngeal nerve injury to LEMG was 8.5 months (range 6-90 months). The majority of patients, 24 of 27 (89%), had motor unit potentials during phonation tasks on LEMG, and only 3 of 27 (11%) patients were electrically silent. Quantitative LEMG showed 287.8 mean turns per second (normal ≥ 400). Motor unit configuration was normal in 12 of 27 (44%), polyphasic in 12 of 27 (44%), and absent in the electrically silent patients. Adductory synkinesis was found in 6 of 20 (30%) patients. CONCLUSION: Chronic vocal fold paralysis is infrequently associated with absent motor-unit recruitment, indicating some degree of preserved innervation and/or reinnervation in these patients. LEMG should be part of the routine workup for chronic VFP prior to consideration of LR. LEVEL OF EVIDENCE: 4. Laryngoscope, 2018.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180122
[Lr] Last revision date:180122
[St] Status:Publisher
[do] DOI:10.1002/lary.27078

  6 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29283938
[Au] Autor:Yetiser S
[Ti] Title:Immediate Hypoglossal-Facial Anastomosis in Patients With Facial Interruption.
[So] Source:J Craniofac Surg;, 2017 Dec 27.
[Is] ISSN:1536-3732
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Hypoglossal-facial anastomosis provides excellent motor supply to the mimetic muscles of the face when there is no chance of recovery of the damaged facial nerve. However, to achieve optimal results, the timing of facial nerve surgery based on electrophysiological testing and clinical evaluation requires close follow-up of the patient. Functional results after delayed surgery are not predictable and depend on the number of surviving fibers, type of injury, severity of damage, degree of infiltration of inflammatory cells, and local fibrosis. Facial hypertonia, synkinesis, and involuntary mass movement are the major problems of delayed reanimation of the facial nerve. Surgery in the vicinity of the facial nerve always aims to preserve neural integrity. However, immediate facial nerve grafting is sometimes required. We present our experience with 4 patients having normal facial function prior to surgery. The facial nerve was severed due to tumor infiltration and instantaneously reconstructed with the hypoglossal nerve. Two patients had House-Brackmann grade-II 10 days and 28 months after surgery, respectively, and another 2 patients had House-Brackmann grade-III facial paralysis 2 weeks and 6 months after surgery, respectively.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180102
[Lr] Last revision date:180102
[St] Status:Publisher
[do] DOI:10.1097/SCS.0000000000004150

  7 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29287848
[Au] Autor:Zur KB; Carroll LM
[Ad] Address:Pediatric Otolaryngology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, 1 Wood ENT, Philadelphia, PA 19104, USA; Department of Otolaryngology: Head & Neck Surgery, Perelman School of Medicine, The University of Pennsylvania, USA. Electronic address: zur@email.chop.edu.
[Ti] Title:Recurrent laryngeal nerve reinnervation for management of aspiration in a subset of children.
[So] Source:Int J Pediatr Otorhinolaryngol;104:104-107, 2018 Jan.
[Is] ISSN:1872-8464
[Cp] Country of publication:Ireland
[La] Language:eng
[Ab] Abstract:Pediatric aspiration is a multifactorial process that is often complex to manage. Recurrent laryngeal nerve (RLN) injury can cause glottic insufficiency and aspiration. We describe three cases of unilateral vocal fold paralysis resulting in aspiration and the successful use of the RLN reinnervation for its treatment. The theory for utilizing the reinnervation procedure is that when glottic closure improves and a less breathy vocalization occurs, then the larynx is better equipped to protect the lower airway and avoid aspiration. Our cases demonstrate stronger voice and improved swallow function, with normalization of modified barium swallow evaluation, at approximately 6-months post reinnervation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 171230
[Lr] Last revision date:171230
[St] Status:In-Process

  8 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 28882981
[Au] Autor:Bonomi M; Vezzoli V; Krausz C; Guizzardi F; Vezzani S; Simoni M; Bassi I; Duminuco P; Di Iorgi N; Giavoli C; Pizzocaro A; Russo G; Moro M; Fatti L; Ferlin A; Mazzanti L; Zatelli MC; Cannavò S; Isidori AM; Pincelli AI; Prodam F; Mancini A; Limone P; Tanda ML; Gaudino R; Salerno M; Francesca P; Maghnie M; Maggi M; Persani L; Italian Network on Central Hypogonadism
[Ad] Address:Department of Clinical Sciences and Community HealthUniversity of Milan, Milan, Italy m.bonomi@auxologico.it marco.bonomi@unimi.it.
[Ti] Title:Characteristics of a nationwide cohort of patients presenting with isolated hypogonadotropic hypogonadism (IHH).
[So] Source:Eur J Endocrinol;178(1):23-32, 2018 Jan.
[Is] ISSN:1479-683X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell (Kallmann syndrome, KS). Other reproductive and non-reproductive anomalies might be present although information on their frequency are scanty, particularly according to the age of presentation. DESIGN: Observational cohort study carried out between January 2008 and June 2016 within a national network of academic or general hospitals. METHODS: We performed a detailed phenotyping of 503 IHH patients with: (1) manifestations of hypogonadism with low sex steroid hormone and low/normal gonadotropins; (2) absence of expansive hypothalamic/pituitary lesions or multiple pituitary hormone defects. Cohort was divided on IHH onset (PPO, pre-pubertal onset or AO, adult onset) and olfactory function: PPO-nIHH ( = 275), KS ( = 184), AO-nIHH ( = 36) and AO-doIHH (AO-IHH with defective olfaction, = 8). RESULTS: 90% of patients were classified as PPO and 10% as AO. Typical midline and olfactory defects, bimanual synkinesis and familiarity for pubertal delay were also found among the AO-IHH. Mean age at diagnosis was significantly earlier and more frequently associated with congenital hypogonadism stigmata in patients with Kallmann's syndrome (KS). Synkinesis, renal and male genital tract anomalies were enriched in KS. Overweight/obesity are significantly associated with AO-IHH rather than PPO-IHH. CONCLUSIONS: Patients with KS are more prone to develop a severe and complex phenotype than nIHH. The presence of typical extra-gonadal defects and familiarity for PPO-IHH among the AO-IHH patients indicates a common predisposition with variable clinical expression. Overall, these findings improve the understanding of IHH and may have a positive impact on the management of patients and their families.
[Mh] MeSH terms primary: Hypogonadism/physiopathology
[Mh] MeSH terms secundary: Adolescent
Adult
Age of Onset
Cohort Studies
Female
Gonadal Steroid Hormones/blood
Gonadotropins/blood
Gonadotropins/deficiency
Humans
Hypogonadism/diagnostic imaging
Hypogonadism/epidemiology
Italy/epidemiology
Male
Obesity/complications
Obesity/epidemiology
Olfaction Disorders/complications
Olfaction Disorders/epidemiology
Overweight/complications
Overweight/epidemiology
Phenotype
Pituitary Hormones/blood
Pituitary Hormones/deficiency
Synkinesis/complications
Synkinesis/epidemiology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Name of substance:0 (Gonadal Steroid Hormones); 0 (Gonadotropins); 0 (Pituitary Hormones)
[Em] Entry month:1711
[Cu] Class update date: 171129
[Lr] Last revision date:171129
[Js] Journal subset:IM
[Da] Date of entry for processing:170909
[St] Status:MEDLINE
[do] DOI:10.1530/EJE-17-0065

  9 / 648 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29107795
[Au] Autor:Khan AO; Khan Z
[Ad] Address:Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates. Electronic address: arif.khan@mssm.edu.
[Ti] Title:Gustatory lid retraction: an unusual congenital cranial dysinnervation disorder.
[So] Source:J AAPOS;, 2017 Oct 28.
[Is] ISSN:1528-3933
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Congenital cranial dysinnervation disorders are developmental abnormalities of cranial nerves that often include abnormal synkinesis. Among the most common ophthalmic congenital cranial dysinnervation disorders are Duane retraction syndrome and the Marcus-Gunn jaw-winking phenomenon. This report documents gustatory lid retraction as an unusual congenital cranial dysinnervation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171111
[Lr] Last revision date:171111
[St] Status:Publisher

  10 / 648 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29100751
[Au] Autor:Fujiwara K; Furuta Y; Yamamoto N; Katoh K; Fukuda S
[Ad] Address:Department of Otolaryngology-Head & Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-Ku, N15W7, Sapporo 0608638, Hokkaido, Japan. Electronic address: boron700@med.hokudai.ac.jp.
[Ti] Title:Factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy.
[So] Source:Auris Nasus Larynx;, 2017 Oct 31.
[Is] ISSN:1879-1476
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To investigate factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy. METHODS: A total of 37 patients with peripheral facial nerve palsy in Teine-Keijinkai Hospital were enrolled in this study. All patients showed synkinesis at 6 months after the onset of facial nerve palsy and were instructed in physical rehabilitation by expert staff from their first visit. The degree of synkinesis was evaluated at 6, 9 and 12 months after the onset of facial nerve palsy based on Sunnybrook facial grading system score and asymmetry in eye opening width. The patients were divided into two groups by age, gender, cause of palsy, electroneurography (ENoG) value, onset of synkinesis, initial treatment and timing of the start of physical rehabilitation. RESULTS: Female patients and younger patients did not show any deterioration in synkinesis. Patients in the lower ENoG group and the later onset of synkinesis group showed significant deterioration in synkinesis after the 6th month from onset of facial palsy. CONCLUSION: Physical rehabilitation was shown to prevent significant deterioration in synkinesis in female and younger patients with facial nerve palsy. Careful follow-up with regard to synkinesis is required in cases in which the facial nerve damage is thought to be severe.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171104
[Lr] Last revision date:171104
[St] Status:Publisher


page 1 of 65 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information