Database : MEDLINE
Search on : Tetralogy and of and Fallot [Words]
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[PMID]: 29520463
[Au] Autor:Mercer-Rosa L; Elci OU; Pinto NM; Tanel RE; Goldmuntz E
[Ad] Address:Division of Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, 34th and Civic Center Blvd, Suite 8NW35, Philadelphia, PA, 19104, USA. mercerrosal@email.chop.edu.
[Ti] Title:22q11.2 Deletion Status and Perioperative Outcomes for Tetralogy of Fallot with Pulmonary Atresia and Multiple Aortopulmonary Collateral Vessels.
[So] Source:Pediatr Cardiol;, 2018 Mar 08.
[Is] ISSN:1432-1971
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Deletion of 22q11.2 (del22q11) is associated with adverse outcomes in patients with tetralogy of Fallot (TOF). We sought to investigate its contribution to perioperative outcome in patients with a severe form of TOF characterized by pulmonary atresia (PA) or severe pulmonary stenosis (PS) and major aortopulmonary collateral arteries (MAPCAS). We conducted a retrospective review of patients with TOF/MAPCAS who underwent staged surgical reconstruction between 1995 and 2006. Groups were compared according to 22q11.2 deletion status using t-tests or the Wilcoxon Rank sum test. We included 26 subjects, 24 of whom survived the initial operation. Of those, 21 subjects had known deletion status and constitute the group for this analysis [15 with no deletion present (ND) and 6 del22q11 subjects]. There was no difference with respect to occurrence of palliative procedure prior to initial operation, or to timing of closure of the ventricular septal defect (VSD). Other than higher prevalence of prematurity (50%) in the del22q11 group versus no prematurity in the ND, the groups were comparable in terms of pre-operative characteristics. The intra- and post-operative course outcomes (length of cardiopulmonary bypass, use of vasopressors, duration of intensive care and length of hospital stay, tube-feeding) were also comparable. Although the del22q11 had longer mechanical ventilation than the ND, this difference was not significant [68 h (range 4-251) vs. 45 h (range 3-1005), p = 0.81]. In this detailed comparison of a small patient cohort, 22q11.2 deletion syndrome was not associated with adverse perioperative outcomes in patients with TOF, PA, and MAPCAS when compared to those without 22q11.2 deletion syndrome. These results are relevant to prenatal and neonatal pre-operative counseling and planning.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1007/s00246-018-1840-9

  2 / 10196 MEDLINE  
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[PMID]: 29515081
[Au] Autor:Kinami H; Morita K; Ko Y; Shinohara G; Hashimoto K
[Ad] Address:Department of Cardiac Surgery, Jikei University School of Medicine, Tokyo, Japan.
[Ti] Title:A Devised Option of Neonatal Palliation for Compromised Tetralogy of Fallot with Absent Pulmonary Valve Syndrome.
[So] Source:Ann Thorac Cardiovasc Surg;, 2018 Mar 07.
[Is] ISSN:2186-1005
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Neonatal primary repair of tetralogy of Fallot (TOF) with absent pulmonary valve (APV) syndrome is associated with high mortality rates. Our plan involves a staged repair that avoids one-stage intracardiac repair (ICR), with a first palliation that closes the main pulmonary orifice using an expanded polytetrafluoroethylene (ePTFE) patch, pulmonary arterioplication, and an adjustable Blalock-Taussig (BT) shunt. This strategy was used for a neonatal case with TOF/APV syndrome with hypoplastic left ventricle (LV). There was evidence of subsequent progressive increase in the LV size, and bronchial compression was relieved and an ICR was performed successfully at 9 months of age.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.5761/atcs.cr.17-00085

  3 / 10196 MEDLINE  
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[PMID]: 29365090
[Au] Autor:Kim H; Sung SC; Choi KH; Lee HD; Kim G; Ko H; Lee YS
[Ad] Address:Department of Thoracic and Cardiovascular Surgery, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongsangnam-do, South Korea.
[Ti] Title:Long-term results of pulmonary valve annular enlargement with valve repair in tetralogy of Fallot.
[So] Source:Eur J Cardiothorac Surg;, 2018 Jan 22.
[Is] ISSN:1873-734X
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:OBJECTIVES: We adopted an operative technique of pulmonary valve (PV) annular enlargement with valve repair in tetralogy of Fallot (TOF) correction to reduce postoperative pulmonary regurgitation (PR) 16 years ago. Here, we have evaluated the long-term results. METHODS: Between April 2000 and August 2005, 43 patients (26 men) with tetralogy of Fallot with pulmonary stenosis underwent PV annular enlargement with valve repair. The median age and body weight at the time of surgery were 14 months and 10.2 kg, respectively. RESULTS: There was no operative mortality. Mean postoperative PR grade at discharge was 0.93 ± 0.40 (none or trivial in 10 patients, mild in 27 patients, mild to moderate in 5 patients and moderate in 1 patient), and the mean postoperative pressure gradient across PV was 13.0 ± 10.9 mmHg. The mean follow-up duration was 131.9 ± 42.9 months. During follow-up, 1 reoperation was performed for residual ventricular septal defect. The mean PR grade at the last follow-up echocardiography was 1.59 ± 0.60 (mild in 17 patients, mild to moderate in 8 patients, moderate in 14 patients, moderate to severe in 1 patient and severe in 3 patients), and the mean pressure gradient was 22.7 ± 9.9 mmHg. We have compared the incidence of moderate or more PR with the incidence of patients who underwent simple transannular patch enlargement through propensity score matching. The PV repair group had a lower incidence of moderate or more PR compared with the simple transannular patch group (40% vs 68%, P = 0.04). CONCLUSIONS: PV annular enlargement with valve repair has reasonable long-term results and yields a lower long-term incidence of significant PR compared with the simple transannular patch enlargement technique.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher
[do] DOI:10.1093/ejcts/ezx497

  4 / 10196 MEDLINE  
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[PMID]: 29244073
[Au] Autor:Østergaard L; Valeur N; Ihlemann N; Bundgaard H; Gislason G; Torp-Pedersen C; Bruun NE; Søndergaard L; Køber L; Fosbøl EL
[Ad] Address:Department of Cardiology, The Heart Centre, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen ø, Denmark.
[Ti] Title:Incidence of infective endocarditis among patients considered at high risk.
[So] Source:Eur Heart J;39(7):623-629, 2018 Feb 14.
[Is] ISSN:1522-9645
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Aims: Patients with prior infective endocarditis (IE), a prosthetic heart valve, or a cyanotic congenital heart disease (CHD) are considered to be at high risk of IE by guidelines. However, knowledge is sparse on the relative risk of IE between these three groups and compared controls. Methods and results: Using Danish nationwide registries (1996-2015), we identified all patients with prior IE, a prosthetic heart valve, or a complex CHD (defined as tetralogy of Fallot, truncus arteriosus, and transposition of great arteries) as well as matched control populations. Patients were followed up until death, end of study period, IE hospitalization, emigration, or a maximum of 10 years of follow-up, whichever came first. Multivariable adjusted Cox proportional hazard analysis was used to compare the risk of IE between the study groups and the matched controls. We included 25 945 patients: 5096 had prior IE, 19 478 had a prosthetic heart valve, and 1371 had complex CHD. The cumulative risk of IE at 10 years of follow-up was 8.8%, 6.0%, and 1.3% for patients with prior IE, a prosthetic valve, and complex CHD, respectively. Patients with prior IE and a prosthetic valve had a significant increased associated risk of IE compared with the matched controls [hazard ratio (HR) 65.4, 95% confidence interval (CI) 43.1-99.1 and HR 19.1, 95% CI 15.0-24.4), respectively]. No events occurred among the matched controls for the complex CHD group and an HR could not be calculated. Conclusion: All IE high-risk groups carried a higher risk of IE than the matched controls from the general population. These results justify the European and American guidelines in considering these groups at high risk of IE.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review
[do] DOI:10.1093/eurheartj/ehx682

  5 / 10196 MEDLINE  
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[PMID]: 29416223
[Au] Autor:Cerovac A; Ljuca D; Khodary B; Grgic G
[Ad] Address:Department of Gynecology and Obstetrics, General Hospital Tesanj, Tesanj, Bosnia and Herzegovina.
[Ti] Title:Pregnacy and Delivery in a Patient After Tetralogy of Fallot Surgery Being Undergone.
[So] Source:Med Arch;72(1):71-73, 2018 Feb.
[Is] ISSN:0350-199X
[Cp] Country of publication:Bosnia and Herzegovina
[La] Language:eng
[Ab] Abstract:Aim: The aim of the paper is to present the risk of pregnancy for mother and her child in a young patient who had a surgery to repair Tetralogy of Fallot (ToF), who gave a birth to her firstborn by having a cesarean section. Case report: 23 years old patient, in 28 weeks of pregnancy was admitted to the clinic due to her medical record. She did not have any subjective complaints. She had two surgeries to repair ToF. After the surgery, she had residual ventricular septal defect (VSD). She had her first surgery 20 years ago (she was 3 years old), and second 7 years ago (she was 16). She had regular check-ups since, and her heart condition was unchanged. Due to her heart surgeries and VSD, a cardiologist indicates that she should deliver by having a c-section when she is 36 weeks pregnant. The patient's heart condition was stabilized and the patient was sent home. She was recommended to have her cardiologist check up on her as she leaves the hospital and to have a gynecological examination in 6 weeks. Conclusion: It can be concluded that team work and prenatal care, in most cases, lead to delivery without complication, both for mother and fetus.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.5455/medarh.2018.72.71-73

  6 / 10196 MEDLINE  
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[PMID]: 29357951
[Au] Autor:Dilli D; Dogan NN; Örün UA; Koç M; Zenciroglu A; Karademir S; Akduman H
[Ad] Address:1Department of Neonatology,Dr Sami Ulus Maternity and Children Research and Training Hospital,University of Health Sciences,Ankara,Turkey.
[Ti] Title:Maternal and neonatal micronutrient levels in newborns with CHD.
[So] Source:Cardiol Young;28(4):523-529, 2018 Apr.
[Is] ISSN:1467-1107
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: It is suggested that folic acid and/or multivitamins, taken periconceptionally, have a role in the prevention of many congenital anomalies. The aim of this study was to determine the serum micronutrient levels in mother-infant pairs with CHD compared with those with healthy newborns and their mothers. METHODS: Serum levels of folic acid, homocysteine, zinc, vitamin A, vitamin D, and vitamin B12 were measured from 108 newborns with CHD (study group) and 103 healthy newborns (control group). The mothers' micronutrient levels were also measured simultaneously. RESULTS: When compared with healthy newborns, for both maternal and neonatal data, homocysteine and zinc levels were higher and vitamin D levels were lower in the study group. In multivariate analysis, only maternal high zinc levels were associated with CHD in the newborns (p=0.02, OR: 0.9, 95% CI 0.8-0.9). The results did not change when analysed for truncal anomalies including truncus arteriosus, tetralogy of Fallot, and d-transposition of great arteries. There were positive correlations between maternal and neonatal levels of micronutrients, except vitamin B12. CONCLUSION: We thought that high homocysteine and zinc levels and low vitamin D levels in mother-infant pairs might have a role in the aetiopathogenesis of CHD. Large-scale, prospective studies are needed to clarify the role of micronutrients in CHDs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.1017/S1047951117002372

  7 / 10196 MEDLINE  
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[PMID]: 29506453
[Au] Autor:Ramman TR; Dutta N; Chowdhuri KR; Agrawal S; Girotra S; Azad S; Radhakrishnan S; Iyer PU; Iyer KS
[Ad] Address:1 Department of Pediatric and Congenital Heart Sciences, Fortis Escorts Heart Institute, New Delhi, India.
[Ti] Title:Left Superior Vena Cava Draining Into Left Atrium in Tetralogy of Fallot-Four Cases of a Rare Association.
[So] Source:World J Pediatr Congenit Heart Surg;:2150135117742625, 2018 Jan 01.
[Is] ISSN:2150-136X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Persistent left superior vena cava is a common congenital anomaly of the thoracic venous system. Left superior vena cava draining into left atrium is a malformation of sinus venosus and caval system. The anomaly may be a cause of unexplained hypoxia even in adults. It may give rise to various diagnostic and technical challenges during cardiac catheterization and open-heart surgery. It is often detected serendipitously during diagnostic workup. Isolated left superior vena cava opening into left atrium is very commonly associated with other congenital heart defects. But tetralogy of Fallot is very rarely associated with persistent left superior vena cava which drains into left atrium. We report four such cases who underwent surgical correction successfully.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher
[do] DOI:10.1177/2150135117742625

  8 / 10196 MEDLINE  
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[PMID]: 29501460
[Au] Autor:Clemente A; Ait Ali L; Avogliero F; Pak V; Squarcia U; Festa P
[Ad] Address:Department of Radiology, Fondazione G. Monasterio CNR - Region Toscana, via Aurelia Sud SNC, 54100 Massa, Italy.
[Ti] Title:Subaortic ventricular pouch in repaired tetralogy of Fallot mimicking right coronary artery aneurysm.
[So] Source:Diagn Interv Imaging;, 2018 Feb 28.
[Is] ISSN:2211-5684
[Cp] Country of publication:France
[La] Language:eng
[Pt] Publication type:LETTER
[Em] Entry month:1803
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:Publisher

  9 / 10196 MEDLINE  
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[PMID]: 29476814
[Au] Autor:Lee T; Weiss AJ; Williams EE; Kiblawi F; Dong J; Nguyen KH
[Ad] Address:Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
[Ti] Title:The Right Axillary Incision: a Potential New Standard of Care for Selected Congenital Heart Surgery.
[So] Source:Semin Thorac Cardiovasc Surg;, 2018 Feb 21.
[Is] ISSN:1532-9488
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVES: Although the median sternotomy has been the traditional approach for congenital heart surgery, young patients and their families often find the midline scar to be cosmetically unappealing. At our center, a right transverse axillary incision has become the standard approach for many congenital cardiac lesions due to its safety, versatility, and unsurpassed aesthetic result. We present our experience with the axillary approach for a diverse array of congenital defects. METHODS: A retrospective review of patients receiving a right transverse axillary incision for congenital cardiac surgery between 2005-2016 was conducted. RESULTS: The right transverse axillary incision was performed in 358 patients for 24 unique procedures. Median age was 5 years (range, 1 month to 60 years) and 225 (63%) patients were female. Median weight was 17 kg (range, 4-124 kg), with 19 (5%) patients weighing less than 6 kg. The most common lesions were atrial septal defects (n=244, 68%) and ventricular septal defects (n=72, 20%). As experience with this approach increased, other repairs included subvalvular aortic membrane resection (n=10, 3%), Tetralogy of Fallot repair (n=7, 2%), ventricular assist device placement (n=3, 1%), and mitral valve repair (n=2, 1%). There were no intra-operative deaths or conversions to sternotomy. In-hospital complications included mortality (n=1, 0.3%), reoperations for bleeding (n=5, 1%), pneumothorax or pleural effusion (n=6, 2%), and permanent pacemaker (n=4, 1%). CONCLUSIONS: The right axillary incision allows a safe and effective repair for a broad range of congenital heart defects and is a potential new standard of care for many patients.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:Publisher

  10 / 10196 MEDLINE  
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[PMID]: 29408326
[Au] Autor:Walsh EP
[Ad] Address:Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts. Electronic address: Ed.walsh@childrens.harvard.edu.
[Ti] Title:The role of ablation therapy for ventricular tachycardia in patients with tetralogy of Fallot.
[So] Source:Heart Rhythm;, 2018 Feb 03.
[Is] ISSN:1556-3871
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:EDITORIAL
[Em] Entry month:1802
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:Publisher


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