Database : MEDLINE
Search on : Tongue and Diseases [Words]
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[PMID]: 29431926
[Au] Autor:Kalaev VN; Nechaeva MS
[Ti] Title:[The study of the frequency of buccal epithelium cells with nuclear in athletes in dependence on the place got in the competition].
[So] Source:Gig Sanit;95(10):992-7, 2016.
[Is] ISSN:0016-9900
[Cp] Country of publication:Russia (Federation)
[La] Language:rus
[Ab] Abstract:Cytogenetic homeostasis ofathletes involved in hand-to-hand armyfighting, depending on the outcome of the fight and the level of aggressiveness has been studied. Status of the genetic apparatus in athletes was evaluated in buccal epithelium with the use of micronucleus test, which is widely usedfor the determination of the influence of various factors on the genetic stability of the organism. Psychological testing of athletes was executed with the use of Spielberger's State-Trait Anger Expression Inventory scale, Bass-Darky questionnaire for the diagnostics of aggression and hostile reactions, Eysenck Personality Questionnaire test for the evaluation ofpsychic conditions and method of U.P. Ilyin and P.A. Kovalev for the identification of the propensity to conflictness and aggressiveness (positive and negative) as the personal characteristics. The place taken by the athlete on the competition was shown to have an impact on the frequency of buccal epithelium cells with nuclear abnormalities (micronuclei, perinuclear vacuoles, notches, protrusions "tongue" and "broken egg"). Losers have nuclear aberrations more than winners. At that in athletes with higher aggressiveness and its attendant psychological characteristics the influence of the outcome of the competition on the number of cells with aberrations core is more pronounced.
[Mh] MeSH terms primary: Aggression
Athletic Performance
Martial Arts
Micronucleus Tests/methods
Mouth Mucosa/pathology
[Mh] MeSH terms secundary: Adolescent
Aggression/physiology
Aggression/psychology
Athletes/psychology
Athletic Performance/physiology
Athletic Performance/psychology
Cytogenetic Analysis/methods
Humans
Male
Martial Arts/physiology
Martial Arts/psychology
Psychological Tests
Statistics as Topic
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180213
[St] Status:MEDLINE

  2 / 12708 MEDLINE  
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[PMID]: 29441920
[Ti] Title:Pancreatic lipase and -amylase inhibitory activities of plants used in Traditional Chinese Medicine (TCM).
[So] Source:Pharmazie;71(7):420-424, 2016 Jul 07.
[Is] ISSN:0031-7144
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:To find new, plant based drugs for the treatment of obesity and/or diabetes mellitus type 2 through the inhibition of essential digestive enzymes, in vitro tests were carried out on selected plants or fungi with weight-reducing, blood glucose-reducing or related potential, used in Traditional Chinese Medicine (TCM). Aqueous and methanolic extracts of 32 Chinese herbal medicines were assayed for their in vitro inhibitory activity against pancreatic lipase (PL) and α-amylase (PA). PL activity was measured by using an enzymatic in vitro assay based on the hydrolysis kinetics of an oleate ester of 4-methylumbelliferone. For the determination of α-amylase activity an enzyme assay based on the hydrolytic cleavage of a modified starch derivative was used. Our findings have shown that the methanolic extract of Lycopus lucidus Turcz. var. hirtus Regel (Lamiaceae) was a very effective PL inhibitor (IC50: 88.3±4.1 µg/mL). A high anti-amylase activity showed the methanolic extract of Trichosanthes kirilowii Maxim. (Curcurbitaceae, IC50: 248.8±67.3 µg/mL). This work provides a priority list of interesting plants for further study with respect to the treatment of obesity and associated metabolic diseases.
[Mh] MeSH terms primary: Lipase/antagonists & inhibitors
Pancreas/enzymology
Plants/chemistry
alpha-Amylases/antagonists & inhibitors
[Mh] MeSH terms secundary: Fungi/chemistry
Hydrolysis
Hymecromone/chemistry
Kinetics
Lycopus/chemistry
Medicine, Chinese Traditional
Pancreas/drug effects
Plant Extracts/pharmacology
Trichosanthes/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Plant Extracts); 3T5NG4Q468 (Hymecromone); EC 3.1.1.3 (Lipase); EC 3.2.1.1 (alpha-Amylases)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:180215
[St] Status:MEDLINE
[do] DOI:10.1691/ph.2016.6569

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[PMID]: 29297570
[Au] Autor:Kaustell KO; Mattila TEA; Hurme T; Salmi PS; Rautiainen RH
[Ad] Address:Natural Resources Institute Finland (Luke), PO Box 2, FI-00791 Helsinki, Finland. kim.kaustell@luke.fi.
[Ti] Title:Predictors for occupational injuries and diseases among commercial fishers in Finland 1996-2015.
[So] Source:Int Marit Health;68(4):196-202, 2017.
[Is] ISSN:2081-3252
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Fishing is a hazardous occupation worldwide. Commercial fishers in Finland are an aging and diminishing population with a high injury rate. Insurance claims data for self-employed Finnish commercial fishers during the years 1996 through 2015 (n = 1951) were analysed to assess predictors for occupational injuries and diseases. Out of the available variables, fishery location, career length, and participation in the voluntary occupational health service programme were not significant predictors. Male gender (OR 2.02; 95% CI 1.37-2.99), Finnish mother tongue vs. Swedish (OR 1.98, 95% CI 1.53-2.55), and higher income levels from fishing (four income categories, OR range: 1.71-3.53) were associated with higher odds for a compensated occupational injury or disease claim among commercial fishers in the final multivariate model. The identified risk groups could be targeted for interventions, and the content of the occupational health service programme should be developed to gain protective effect.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.5603/IMH.2017.0037

  4 / 12708 MEDLINE  
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[PMID]: 29269592
[Au] Autor:Seerangaiyan K; Jüch F; Winkel EG
[Ad] Address:Department of Periodontology, Center for Dentistry and Oral Hygiene, University Medical Center Groningen, Groningen, The Netherlands.
[Ti] Title:Tongue coating: its characteristics and role in intra-oral halitosis and general health-a review.
[So] Source:J Breath Res;12(3):034001, 2018 Mar 06.
[Is] ISSN:1752-7163
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Tongue coating (TC), a grayish-white deposit on the tongue, is the main cause of intra-oral halitosis (IOH), a socially unacceptable condition. This review covers the general features of TC, including its formation and the factors that influence it. Volatile sulfur compounds (VSCs) are the principal elements of IOH, and TC and periodontal diseases are the two main sources of VSCs. This review covers the relationship between VSCs, TC, and periodontal disease. We comprehensively discuss the methods employed to quantify TC, its microbial composition, its influence on general health and its importance in general medicine.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:In-Data-Review
[do] DOI:10.1088/1752-7163/aaa3a1

  5 / 12708 MEDLINE  
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[PMID]: 29480863
[Au] Autor:Wu TC; Wu KL; Hu WL; Sheen JM; Lu CN; Chiang JY; Hung YC
[Ad] Address:Department of Chinese Medicine.
[Ti] Title:Tongue diagnosis indices for upper gastrointestinal disorders: Protocol for a cross-sectional, case-controlled observational study.
[So] Source:Medicine (Baltimore);97(2):e9607, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Upper gastrointestinal disorders are common in clinical practice, for example, gastritis, peptic ulcer disease, and gastroesophageal reflux disease. Panendoscopy or upper gastrointestinal endoscopy is viewed as the primary tool for examining the upper gastrointestinal mucosa, and permitting biopsy and endoscopic therapy. Although panendoscopy is considered to be a safe procedure with minimal complications, there are still some adverse effects, and patients are often anxious about undergoing invasive procedures. Traditional Chinese medicine tongue diagnosis plays an important role in differentiation of symptoms because the tongue reflects the physiological and pathological condition of the body. The automatic tongue diagnosis system (ATDS), which noninvasively captures tongue images, can provide objective and reliable diagnostic information. METHODS: This protocol is a cross-sectional, case-controlled observational study investigating the usefulness of the ATDS in clinical practice by examining its efficacy as a diagnostic tool for upper gastrointestinal disorders. Volunteers over 20 years old with and without upper gastrointestinal symptoms will be enrolled. Tongue images will be captured and the patients divided into 4 groups according to their panendoscopy reports, including a gastritis group, peptic ulcer disease group, gastroesophageal reflux disease group, and healthy group. Nine primary tongue features will be extracted and analyzed, including tongue shape, tongue color, tooth mark, tongue fissure, fur color, fur thickness, saliva, ecchymosis, and red dots. OBJECTIVES: The aim of this protocol is to apply a noninvasive ATDS to evaluate tongue manifestations of patients with upper gastrointestinal disorders and examine its efficacy as a diagnostic tool.
[Mh] MeSH terms primary: Digestive System Diseases/diagnosis
Medicine, Chinese Traditional
Tongue
[Mh] MeSH terms secundary: Case-Control Studies
Cross-Sectional Studies
Digestive System Diseases/pathology
Medicine, Chinese Traditional/instrumentation
Medicine, Chinese Traditional/methods
Pattern Recognition, Automated
Tongue/pathology
[Pt] Publication type:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180227
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009607

  6 / 12708 MEDLINE  
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[PMID]: 29452069
[Au] Autor:Shibata A; Kimura M; Ishibashi K; Umemura M
[Ad] Address:Clinical Fellow, Department of Oral and Maxillofacial Surgery, Ogaki Municipal Hospital, Ogaki, Japan. Electronic address: akio.st83@gmal.com.
[Ti] Title:Idiopathic Isolated Unilateral Hypoglossal Nerve Palsy: A Report of 2 Cases and Review of the Literature.
[So] Source:J Oral Maxillofac Surg;, 2018 Feb 02.
[Is] ISSN:1531-5053
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Hypoglossal nerve palsy (HNP) is a common finding in neurologic diseases when associated with other cranial nerve palsies or further pathology and exhibits characteristic clinical manifestations, including unilateral atrophy of the musculature of the tongue. It occasionally appears as the initial or solitary sign of an intracranial or extracranial space-occupying lesion, head or neck injury, or vascular abnormality of the internal carotid artery. There are few cases of idiopathic isolated unilateral HNP, which should be diagnosed through exclusion. This report describes 2 patients who had different outcomes and presents a literature review of idiopathic isolated unilateral HNP. Case 1 was a 71-year-old man who was referred with a 1-month history of dysphagia and speech impairment. Intraoral examination disclosed marked left-side hemiatrophy of the tongue and deviation toward the left on protrusion. At coronal Tl-weighted magnetic resonance imaging, left-side hemiatrophy of the tongue was clearly visible through deviation of the median septum to the left. The patient was diagnosed with idiopathic isolated unilateral HNP through exclusion and was treated with steroids and mecobalamin, but he did not recover. Case 2 was a 32-year-old man complaining of tongue weakness for 2 days. On examination, left HNP was evident, with deviation of the tongue to the left on protrusion. He was diagnosed with idiopathic isolated unilateral HNP through exclusion and was treated with steroids. After 3 weeks, the patient had completely recovered. To the best of the authors' knowledge, this is the first detailed literature review on idiopathic isolated unilateral HNP. This condition is very rare but should be considered for diagnosis. It warrants a thorough and stepwise approach for etiologic diagnosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180304
[Lr] Last revision date:180304
[St] Status:Publisher

  7 / 12708 MEDLINE  
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[PMID]: 29480592
[Au] Autor:de Lima M; Hajj G; de Lima V; Alves FA
[Ad] Address:Stomatology Department, A.C. Camargo Cancer Center, São Paulo, SP, Brazil.
[Ti] Title:Breast cancer patients have increased risk of developing mTOR inhibitor-associated stomatitis.
[So] Source:Oral Dis;24(1-2):207-209, 2018 Mar.
[Is] ISSN:1601-0825
[Cp] Country of publication:Denmark
[La] Language:eng
[Ab] Abstract:A total of 115 patients who used everolimus were evaluated. The mean age was 57 (±13.3) years old, and 87 patients were women (75.6%). mTOR inhibitor-associated stomatitis (mIAS) was observed in 36 patients (31.3%). The lesions ranged from 0.5 cm to 1.5 cm, and the tongue was the main site affected. In addition, 21 patients (58.3%) required a dose reduction of everolimus due to mIAS. Patients who had breast cancer presented 2.29-fold higher risk for developing mIAS when compared to patients with kidney or neuroendocrine tumors. This study emphasizes the high prevalence of mIAS in patients using everolimus, in particular, in patients with breast cancer.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180226
[Lr] Last revision date:180226
[St] Status:In-Process
[do] DOI:10.1111/odi.12771

  8 / 12708 MEDLINE  
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[PMID]: 29443769
[Au] Autor:Cheng H; Yi D; Si J; Hu J; Yang Y; Peng J
[Ad] Address:National Academy of Innovation Strategy, China Association for Science and Technology.
[Ti] Title:Establishment of Comprehensive Indicators in TCM Pectoral-qi Case Report Based on Experts Diagnosis and Self-test Technology.
[So] Source:Medicine (Baltimore);97(7):e9916, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: To establish TCM Pectoral-qi comprehensive indicators and highlight the inner structure among different variables in an objective way, the article uses Partial Least Square Second-order Latent Variable Model (PLS-SLVM) and accomplishes 3 different comprehensive indicators based on both experts diagnosis and self-test data. SLVM includes a measurement model that defines the relationship between observed variables and latent variables and a structure model that imputes relationships between latent variables. The article focuses on PLS as the estimation method. Without normal distribution and independence assumptions, PLS uses objective weighting methods based on the data. Bootstrap method (B = 200) is used to calculate the mean value and standard errors of the PLS estimates. The article chooses the percentile interval to obtain the confidence interval of PLS parameters. PATIENT CONCERNS: The patients were diagnosed by the means of experts diagnosis and self-test technology. On the one hand, the patients want to know the effect of self-test by wearing a kind of instrument. On the other hand, we want to establish TCM Pectoral-qi comprehensive indicators and highlight the inner structure among different variables in an objective way. DIAGNOSES: The group of 59 subjects are the same no matter whether they were diagnosed through TCM Pectoral-qi Assessment Questionnaire of self-test technology. INTERVENTIONS: The same group of 59 subjects keep wearing the instrument for hours and get the self-test data consequently. OUTCOMES: As one of comprehensive indicator establishing methods, PLS-SLVM highlights the structure state among variables and improves the evaluation efficiency. Furthermore, it provides a new tool and method in TCM diseases prevention and health security. LESSONS: As expected, PLS-SLVM is a useful tool due to its nonassumption of normal distribution and independence with consideration of correlation among different variables. Thus PLS-SLVM can be applied in ordinal data from assessment questionnaire and continuous data about physicochemical indexes for the same group of people. It displays that PLS-SLVM builds a connection between TCM experts diagnosis and the self-testing technology.
[Mh] MeSH terms primary: Health Status Indicators
Medicine, Chinese Traditional
Outcome Assessment (Health Care)
Qi
[Mh] MeSH terms secundary: Algorithms
China
Dimensional Measurement Accuracy
Humans
Medicine, Chinese Traditional/methods
Medicine, Chinese Traditional/standards
Models, Theoretical
Observer Variation
Outcome Assessment (Health Care)/methods
Outcome Assessment (Health Care)/standards
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180222
[Lr] Last revision date:180222
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180215
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009916

  9 / 12708 MEDLINE  
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[PMID]: 29319549
[Au] Autor:Moura CA; Herrera P; Magalhães J; Moura CG
[Ti] Title:Tongue Indentations Secondary to Light Chain Amyloidosis.
[So] Source:J Clin Rheumatol;24(2):98, 2018 Mar.
[Is] ISSN:1536-7355
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180221
[Lr] Last revision date:180221
[St] Status:In-Data-Review
[do] DOI:10.1097/RHU.0000000000000639

  10 / 12708 MEDLINE  
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[PMID]: 29268975
[Au] Autor:Wen QT; Wang T; Yu DH; Wang ZR; Sun Y; Liang CW
[Ad] Address:Dental Medical Center, People's Hospital of Hainan Province, Haikou 570100, China.
[Ti] Title:Development of a mouse model of arecoline-induced oral mucosal fibrosis.
[So] Source:Asian Pac J Trop Med;10(12):1177-1184, 2017 Dec.
[Is] ISSN:2352-4146
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To develop a BALB/c mouse model of oral submucous fibrosis (OSF) induced by arecoline and to exhibit an accumulation of collagen and angiogenesis changes. METHODS: BALB/c mice were randomly assigned to either the control (distilled water) or experimental group (arecoline) (n = 40). Eight mice from each group were sacrificed every 4 weeks since 8 weeks post treatment. Changes in histopathologic features, levels of collagen type I and collagen type III, and angiogenesis were measured. RESULTS: In the 8th week, epithelium atrophy, collagen cumulation and micrangium pathologic changes in the lamina propria were observed in the oral mucosa. In the 20th week, hyaline degeneration of the connective tissues was observed on the tongue and palate mucosa. The angiogenesis and collagen type I changed significantly as the diseases advanced (P < 0.05); however, collagen type III was not statistically different. CONCLUSIONS: An OSF model involving mice can be rapidly induced by drinking a high-dose of arecoline. OSF angiogenic changes in mice primarily decrease and collagen accumulation is mainly collagen type I.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180219
[Lr] Last revision date:180219
[St] Status:In-Data-Review


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