Database : MEDLINE
Search on : Triclosan [Words]
References found : 2960 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 296 go to page                         

  1 / 2960 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29524920
[Au] Autor:Sakhi AK; Sabaredzovic A; Papadopoulou E; Cequier E; Thomsen C
[Ad] Address:Department of Environmental Exposure and Epidemiology, Division of Infection Control, Environment and Health, Norwegian Institute of Public Health, P.O. Box 4404, Nydalen, 0403 Oslo, Norway. Electronic address: amritkaur.sakhi@fhi.no.
[Ti] Title:Levels, variability and determinants of environmental phenols in pairs of Norwegian mothers and children.
[So] Source:Environ Int;114:242-251, 2018 Mar 07.
[Is] ISSN:1873-6750
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Exposure to environmental phenols including parabens, bisphenols (BPs), oxybenzone/benzophenone-3 (BP-3) and triclosan (TCS) is ubiquitous. Due to evidence of their estrogenic activity, they have been considered as chemicals of concern. The exposure of the Norwegian population to these compounds is presently unknown. AIMS: To measure urinary levels of twelve different environmental phenols including four emerging bisphenols: S, F, B and AF (abbreviated as BPS, BPF, BPB and BPAF, respectively) in a healthy Norwegian population. We have calculated short-term variability, estimated daily intakes and investigated important determinants of exposure. METHODS: Urine samples were collected from mothers (n = 48) and their children (n = 56) during spring/summer 2012 in two counties in Norway. RESULTS: Six environmental phenols namely methyl, ethyl and propyl paraben, BPA, BP-3 and TCS were detected in almost 100% of the urine samples. Among the emerging bisphenols, BPS was detected most frequently in the urine samples (42-48%) followed by BPF (4-15%). Parabens were positively and significantly correlated to each other in both mothers and children. Levels of parabens and BP-3 were higher in mothers compared to children. All mothers and children had lower estimated daily intakes (back calculated from the urinary concentrations) of parabens and BPA than the respective acceptable and tolerable daily intakes (ADIs and TDIs) established by the European Food Safety Authority (EFSA). Observed intraclass correlation coefficients (ICCs) indicated moderate to high reliability of spot urine measurements for all the environmental phenols (ICCs: 0.70-0.97). Use of hair products, deodorants, face and hand creams were significantly associated with higher urinary levels of parabens. CONCLUSIONS: Occurrence of environmental phenols in healthy Norwegian women and children is abundant. Among emerging bisphenols, there is widespread exposure to BPS. A single spot urine sample can be used for estimating short-term exposures of environmental phenols. Urinary levels of parabens were associated with use of PCPs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher

  2 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29515975
[Au] Autor:Wang C; Yu Z; Shi X; Tang X; Wang Y; Wang X; An Y; Li S; Li Y; Wang X; Luan W; Chen Z; Liu M; Yu L
[Ad] Address:Key Laboratory of Zoonoses Research, Ministry of Education, Institute of Zoonosis, First Hospital of Jilin University, College of Veterinary Medicine, Jilin University, Changchun, China.
[Ti] Title:Triclosan Enhances the Clearing of Pathogenic Intracellular or but Disturbs the Intestinal Microbiota through mTOR-Independent Autophagy.
[So] Source:Front Cell Infect Microbiol;8:49, 2018.
[Is] ISSN:2235-2988
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:Triclosan (TCS) is a broad-spectrum antimicrobial agent, whose well-known antibacterial mechanism is inhibiting lipid synthesis. Autophagy, an innate immune response, is an intracellular process that delivers the cargo including pathogens to lysosomes for degradation. In this study, we first demonstrated that TCS induced autophagy in a dose-dependent manner in non-phagocytic cells (HeLa) and in macrophages (Raw264.7) and . The western blot results also revealed that TCS induced autophagy via the AMPK/ULK1 and JNK/ERK/p38 pathways independent of mTOR. The immunofluorescence results indicated that TCS up-regulated the expression of the ubiquitin receptors NDP52 and p62 and strengthened the co-localization of these receptors with Typhimurium ( . typhimurium) or ( ) in infected MΦ cells. In addition, sub-lethal concentrations of TCS enhanced the clearing of the pathogens . typhimurium or in infected MΦ and in corresponding mouse infection models . Specifically, we found that a sub-inhibitory concentration of TCS induced autophagy, leading to an imbalance of the intestinal microflora in mice through the analysis of 16s rRNA Sequencing. Together, these results demonstrated that TCS induced autophagy, which enhanced the killing against pathogenic . typhimurium or within mammal cells but broke the balance of the intestinal microflora.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review
[do] DOI:10.3389/fcimb.2018.00049

  3 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29506550
[Au] Autor:Kalloo G; Calafat AM; Chen A; Yolton K; Lanphear BP; Braun JM
[Ad] Address:Department of Epidemiology, Brown University, Providence, RI, USA. geetika_kalloo@brown.edu.
[Ti] Title:Early life Triclosan exposure and child adiposity at 8Years of age: a prospective cohort study.
[So] Source:Environ Health;17(1):24, 2018 Mar 05.
[Is] ISSN:1476-069X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Triclosan is an antimicrobial agent that may affect the gut microbiome and endocrine system to influence adiposity. However, little data from prospective studies examining prenatal and childhood exposures exist.We investigated the relationship between multiple, prospective early life measure of triclosan exposure and child adiposity. METHODS: In a prospective cohort of 220 mother-child pairs from Cincinnati, OH (enrolled 2003-2006), we quantified triclosan in urine samples collected twice during pregnancy, annually from 1 to 5years of age, and once at 8years. We assessed child adiposity at age 8years using body mass index (BMI), waist circumference, and bioelectric impedance. We estimated covariate-adjusted associations of child adiposity with a 10-fold increase in average prenatal, average early childhood (average of 1-5years), and 8-year triclosan concentrations. RESULTS: Among all children, there was no association between triclosan and child adiposity. While urinary triclosan concentrations at all three time periods were weakly, imprecisely, and inversely associated with all three measures of adiposity among girls, these associations did not differ significantly from those in boys (sex x triclosan p-values> 0.35). Among girls, the strongest associations were generally observed for prenatal triclosan when we adjusted for all three triclosan concentrations and covariates in the same model; BMI z-score (: -0.13; 95% CI: -0.42, 0.15), waist circumference (: - 1.7cm; 95% CI: -4.2, 0.7), and percent body fat ( :-0.6; 95% CI: -2.7, 1.3). In contrast, the associations between triclosan concentrations and adiposity measures were inconsistent among boys. CONCLUSION: We did not observe evidence of an association of repeated urinary triclosan concentrations during pregnancy and childhood with measures of child adiposity at age 8years in this cohort.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review
[do] DOI:10.1186/s12940-018-0366-1

  4 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29175396
[Au] Autor:Wang F; Liu F; Chen W; Xu R; Wang W
[Ad] Address:School of Biological Science, Luoyang Normal University, Luoyang, 471022, China; Cold Water Fish Breeding Engineering Technology Research Center of Henan Province, Luoyang, 471022, China. Electronic address: wangfan7677@163.com.
[Ti] Title:Effects of triclosan (TCS) on hormonal balance and genes of hypothalamus-pituitary- gonad axis of juvenile male Yellow River carp (Cyprinus carpio).
[So] Source:Chemosphere;193:695-701, 2018 Feb.
[Is] ISSN:1879-1298
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Triclosan (TCS) is a broad spectrum antimicrobial agent which has been widely dispersed and determinated in the aquatic environment. However, the effects of TCS on reproductive endocrine in male fish are poorly understood. In this study, male Yellow River carp (Cyprinus carpio) were exposed to 0, 1/5, 1/10 and 1/20 LC (96h LC of TCS to carp) TCS under semi-static conditions for 42d. Vitellogenin (Vtg), 17-estradiol (E ), testosterone(T), gonadotropin (GtH), and gonadotropin-releasing hormone (GnRH) levels were measured by enzyme-linked immunosorbent assay (ELISA). Meanwhile, we also examined the mRNA expressions of aromatase, GtHs-, GnRH, estrogen receptor (Er), and androgen receptor (Ar) by quantitative Real-time Polymerase Chain Reaction (qRT-PCR). TCS induced Vtg levels of hepatopancreas, E levels of serum, and inhibited Ar and Er mRNA levels, suggesting that the induction of Vtg production by TCS was indirectly caused by non-Er pathways. TCS-induced Vtg levels by interfering with the reproductive axis at plenty of latent loci of male carps: (a) TCS exposure increased the aromatase mRNA expression of hypothalamus and gonad aromatase, consequently increasing serum concentrations of E to induce Vtg in hepatopancreas; (b) TCS treatment changed GtH- and GnRH mRNA expression and secretion, causing the disturbance of reproductive endocrine; (c) TCS exposure decreased Ar mRNA levels, indicating potential Ar-mediated antiandrogen action. These mechanisms showed that TCS may induce Vtg production in male carp by non-Er-mediated pathways.
[Mh] MeSH terms primary: Carps/metabolism
Triclosan/toxicity
Water Pollutants, Chemical/toxicity
[Mh] MeSH terms secundary: Animals
Anti-Infective Agents/toxicity
Aromatase/genetics
Endocrine System/drug effects
Enzyme-Linked Immunosorbent Assay
Estradiol/analysis
Gonadotropin-Releasing Hormone/analysis
Gonadotropin-Releasing Hormone/genetics
Gonads/enzymology
Gonads/metabolism
Hepatopancreas/metabolism
Hormones/metabolism
Hypothalamus/metabolism
Male
Pituitary Gland/metabolism
RNA, Messenger/analysis
Real-Time Polymerase Chain Reaction
Receptors, Estrogen/genetics
Reproduction/drug effects
Testosterone/analysis
Vitellogenins/analysis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Anti-Infective Agents); 0 (Hormones); 0 (RNA, Messenger); 0 (Receptors, Estrogen); 0 (Vitellogenins); 0 (Water Pollutants, Chemical); 33515-09-2 (Gonadotropin-Releasing Hormone); 3XMK78S47O (Testosterone); 4NM5039Y5X (Triclosan); 4TI98Z838E (Estradiol); EC 1.14.14.1 (Aromatase); EC 1.14.14.1 (CYP19A1 protein, human)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:171128
[St] Status:MEDLINE

  5 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29520826
[Au] Autor:Ribeiro FV; Casati MZ; Casarin RC; Corra MG; Cirano FR; Negri BM; Pimentel SP
[Ad] Address:Dental Research Division, School of Dentistry, Paulista University, So Paulo, So Paulo, Brazil.
[Ti] Title:Impact of a triclosan-containing toothpaste during the progression of experimental peri-implant mucositis: Clinical parameters and local pattern of osteo-immunoinflammatory mediators in peri-implant fluid.
[So] Source:J Periodontol;89(2):203-212, 2018 Feb.
[Is] ISSN:1943-3670
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: This study evaluated the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in peri-implant crevicular fluid (PICF) and in clinical parameters during progression of peri-implant mucositis. METHODS: Twenty-two clinically healthy patients with an implant-supported single-unit crown were enrolled in this double-blind, randomized, crossover study carried out in two phases of 21 days each. During an experimental 3-week period of undisturbed plaque accumulation in the implants, patients were randomly assigned to use three times/day: triclosan (n=11), triclosan/copolymer/fluoride toothpaste; or placebo (n=11), fluoride toothpaste. After a professional prophylaxis, a washout period of 30 days was established. Clinical parameters and 15 osteo-immunoinflammatory mediators in the PICF were evaluated at baseline and at 3, 7, 14, and 21 days. RESULTS: Both groups showed increase in plaque index at implant sites from the 3rd until the 21st day (P<0.05). Only triclosan treatment was able to avoid an increase in bleeding on probing (BOP) throughout the follow-ups (P>0.05), whereas a significant intensification in BOP was observed from the 14th day in the placebo-treated sites (P<0.05). Lower interleukin (IL)-10 concentrations were detected in the placebo group at the 21st day when compared with triclosan-treated implant sites (P<0.05). IL-10 levels were reduced and IL-1 concentrations were increased at 21 days when compared with baseline only in placebo-treated sites (P<0.05). Osteoprotegerin levels significantly increased from the 14th until the 21st day only in triclosan-treated sites (P<0.05). CONCLUSION: Triclosan-containing toothpaste controls clinical inflammation and interferes positively in the profile of osteo-immunoinflammatory mediators during progression of experimental peri-implant mucositis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review
[do] DOI:10.1002/JPER.17-0302

  6 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29519272
[Ti] Title:LED-Based UV Oxidation of Pharmaceuticals: Effects of Wavelength and Intensity, pH, and TiO2 Loading.
[So] Source:Water Environ Res;, 2018 Feb 16.
[Is] ISSN:1061-4303
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The presence of pharmaceuticals in water resources has alarmed water and health authorities. In this study, ultraviolet(UV)-based oxidation was evaluated to decompose sulfamethoxazole, ibuprofen, and triclosan in comparison. In particular, as an alternative UV source to problematic conventional mercury lamps, light emitting diode (LED), so-called UV-LED, was evaluated for the decomposition of the pharmaceuticals in water under various conditions varying UV wavelength, irradiation intensity, reaction pH, and TiO2 loading. Photolytic decomposition of the pharmaceuticals was also compared with their photocatalytic decomposition. Photolytic decomposition of the pharmaceuticals was solely determined by relation between their UV absorption characteristics and the UV emission spectra of LEDs. Both photolytic decomposition and photocatalytic decomposition were greatly affected by reaction pH. The presence of TiO2 in cases that significant photolysis was present, rather inhibited the overall decomposition process. However, in all cases, photocatalysis showed better mineralization than photolysis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.2175/106143017X15131012152898

  7 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518598
[Au] Autor:Palmiotto M; Castiglioni S; Zuccato E; Manenti A; Riva F; Davoli E
[Ad] Address:International Centre for Pesticides and Health Risk Prevention (ICPS), ASST Fatebenefratelli-Sacco, Via Giovanni Battista Grassi 74, 20157, Milan, Italy; IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Department of Environmental Health Sciences, Via La Masa 19, 20156, Milan, Italy.
[Ti] Title:Personal care products in surface, ground and wastewater of a complex aquifer system, a potential planning tool for contemporary urban settings.
[So] Source:J Environ Manage;214:76-85, 2018 Mar 05.
[Is] ISSN:1095-8630
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The use and discharge of personal care products (PCPs) result in their presence in the aquatic environment. This study investigates the occurrence and fate of some PCPs in wastewater, surface and groundwater in an urbanized area in the North of Italy. We investigated four UV filters: phenylbenzimidazole sulfonic acid (PBSA), benzophenone-3 (BP3), benzophenone-4 (BP4) and 4 methyl-benzilidine-camphor (4-MBC), and two antibacterial agents: triclosan (TCS) and triclocarban (TCC). BP3, BP4 and PBSA were detected in all WWTPs and concentrations ranged 27-822ng/L (BP4>PBSA>BP3). TCS was the only disinfectant detected in wastewater and ranged from <0.2 to 1690ng/L. Removal efficiencies in WWTPs were good for BP3 and TCS (80-100%), but were quite low for PBSA and BP4 (0-40%). Consequently, PBSA and BP4 were the most abundant substances in surface water, detected up to 560.4ng/L. TCS was also found in surface water (<0.2-161.0ng/L). Only PBSA and TCS were found in untreated groundwater, and levels were higher in wells close to rivers, suggesting the contribution of surface water to this contamination, but not from the catchment and the sewer networks. These PCPs were confirmed to be ubiquitous in all the aquifers sampled, being reliable descriptors of human presence. The use of these data as direct indicators of pollutant's loads for the aquifers deriving from human presence could provide early warnings on chemicals that are continuously introduced into surface waters, identifying dynamic urban trends and suggesting paths for the planning in urban regions and for appropriate investment and rehabilitation strategies of infrastructure.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher

  8 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29477955
[Au] Autor:Messerlian C; Mustieles V; Minguez-Alarcon L; Ford JB; Calafat AM; Souter I; Williams PL; Hauser R; Environment and Reproductive Health (EARTH) Study Team
[Ad] Address:Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: cmesser@hsph.harvard.edu.
[Ti] Title:Preconception and prenatal urinary concentrations of phenols and birth size of singleton infants born to mothers and fathers from the Environment and Reproductive Health (EARTH) study.
[So] Source:Environ Int;114:60-68, 2018 Feb 22.
[Is] ISSN:1873-6750
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Although pregnancy concentrations of some phenols have been associated with infant size at birth, there is limited data on the effect of preconception exposure. OBJECTIVE: We aimed to examine paternal and maternal preconception and maternal prenatal urinary phenol concentrations in relation to birth weight and head circumference. METHODS: We evaluated 346 singletons born to 346 mothers and 184 fathers (184 couples) from a prospective preconception cohort of subfertile couples from the Environment and Reproductive Health (EARTH) Study in Boston, USA. We used multiple urine samples collected before the index pregnancy in both men and women to estimate mean preconception urinary benzophenone-3, triclosan, butylparaben, propylparaben, methylparaben, or ethylparaben concentrations. We also estimated mean maternal prenatal urinary phenol concentrations by averaging trimester-specific urine samples. Birth weight and head circumference were abstracted from delivery records. We estimated the association of natural log-phenol concentrations with birth outcomes using multivariable linear regression models, adjusting for known confounders. RESULTS: In adjusted models, each log-unit increase in paternal preconception benzophenone-3 concentration was associated with a 137 g increase in birth weight (95% CI: 60, 214). Additional adjustment for prenatal benzophenone-3 concentration strengthened this association. None of the maternal preconception phenol concentrations were associated with birth weight. However, maternal prenatal triclosan concentrations were associated with a 38 g decrease in birth weight (95% CI: -76, 0). Few associations were observed between phenols and head circumference except for a decrease of 0.27 cm (95% CI: -54, 0) in relation to maternal preconception methylparaben concentration. CONCLUSIONS: Although our findings should be interpreted in light of inherent study limitations, these results suggest potential evidence of associations between some paternal or maternal phenol concentrations and birth size.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  9 / 2960 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29474822
[Au] Autor:Smarr MM; Honda M; Kannan K; Chen Z; Kim S; Louis GMB
[Ad] Address:Office of the Director, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 6710B Rockledge Drive, Bethesda, MD 20829, USA; Department of Environmental Health, Rollins School of Public Heal
[Ti] Title:Male urinary biomarkers of antimicrobial exposure and bi-directional associations with semen quality parameters.
[So] Source:Reprod Toxicol;77:103-108, 2018 Feb 21.
[Is] ISSN:1873-1708
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Antimicrobials including parabens, triclosan, and triclocarban have endocrine disrupting properties. Among 501 male partners of couples planning to become pregnant, preconception urinary biomarkers of parabens, triclosan and triclocarban exposure were quantified in spot urine samples. Men also provided two fresh semen samples collected approximately one month to undergo 24-h semen quality analysis. Linear mixed-effects models, adjusted for creatinine, race, age and body mass index, were utilized to assess the relationship between log transformed chemical concentrations rescaled by their standard deviations and semen parameters. Methyl, ethyl and butyl parabens, were associated with diminished sperm count and several sperm motility parameters. Hydroxylated paraben metabolites and triclosan were significantly positively associated with select semen quality parameters. Overall, our findings suggest that specific urinary parabens found in consumer goods (methyl, ethyl and butyl parabens) may adversely impact sperm quality parameters among reproductive-age male partners of couples trying for pregnancy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher

  10 / 2960 MEDLINE  
              first record previous record
select
to print
Photocopy
SciELO Brazil full text

[PMID]: 29412223
[Au] Autor:Genari B; Leitune VCB; Jornada DS; Aldrigui BR; Pohlmann AR; Guterres SS; Samuel SMW; Collares FM
[Ad] Address:Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Dental Materials Laboratory, Porto Alegre, RS, Brazil.
[Ti] Title:Effect on adhesion of a nanocapsules-loaded adhesive system.
[So] Source:Braz Oral Res;32:e008, 2018 Feb 01.
[Is] ISSN:1807-3107
[Cp] Country of publication:Brazil
[La] Language:eng
[Ab] Abstract:This study aimed to evaluate the in situ degree of conversion, contact angle, and immediate and long-term bond strengths of a commercial primer and an experimental adhesive containing indomethacin- and triclosan-loaded nanocapsules (NCs). The indomethacin- and triclosan-loaded NCs, which promote anti-inflammatory and antibacterial effects through controlled release, were incorporated into the primer at a concentration of 2% and in the adhesive at concentrations of 1, 2, 5, and 10%. The in situ degree of conversion (DC, n=3) was evaluated by micro-Raman spectroscopy. The contact angle of the primer and adhesive on the dentin surface (n = 3) was determined by an optical tensiometer. For the microtensile bond strength TBS test (12 teeth per group), stick-shaped specimens were tested under tensile stress immediately after preparation and after storage in water for 1 year. The data were analyzed using two-way ANOVA, three-way ANOVA and Tukey's post hoc tests with α=0.05. The use of the NC-loaded adhesive resulted in a higher in situ degree of conversion. The DC values varied from 75.07 8.83% to 96.18 0.87%. The use of NCs in only the adhesive up to a concentration of 5% had no influence on the bond strength. The contact angle of the primer remained the same with and without NCs. The use of both the primer and adhesive with NCs (for all concentrations) resulted in a higher contact angle of the adhesive. The longitudinal TBS was inversely proportional to the concentration of NCs in the adhesive system, exhibiting decreasing values for the groups with primer containing NCs and adhesives with increasing concentrations of NCs. Adhesives containing up to 5% of nanocapsules and primer with no NCs maintained the in situ degree of conversion, contact angle, and immediate and long-term bond strengths. Therefore, the NC-loaded adhesive can be an alternative method for combining the bond performance and therapeutic effects. The use of an adhesive with up to 5% nanocapsules containing indomethacin and triclosan and a primer with no nanocapsules maintained the long-term bond performance.
[Mh] MeSH terms primary: Dental Bonding/methods
Indomethacin/chemistry
Nanocapsules/chemistry
Resin Cements/chemistry
Triclosan/chemistry
[Mh] MeSH terms secundary: Analysis of Variance
Animals
Cattle
Dental Restoration Failure
Dentin/drug effects
Materials Testing
Phase Transition/drug effects
Polymerization/drug effects
Reference Values
Reproducibility of Results
Spectrum Analysis, Raman
Surface Properties/drug effects
Tensile Strength
Time Factors
[Pt] Publication type:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Name of substance:0 (Nanocapsules); 0 (Resin Cements); 4NM5039Y5X (Triclosan); 90881-69-9 (Scotchbond); XXE1CET956 (Indomethacin)
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[Js] Journal subset:D; IM
[Da] Date of entry for processing:180208
[St] Status:MEDLINE


page 1 of 296 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information