Database : MEDLINE
Search on : Trochlear and Nerve and Diseases [Words]
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[PMID]: 29398228
[Au] Autor:Roberts Martínez-Aguirre I; de Las Heras Gómez de Liaño ME; Lacosta Asín V; Zarzosa Martín ME; Alonso Maroto JM; Pérez-Salvador García E
[Ad] Address:Servicio de Oftalmología, Hospital Universitario de Burgos, Burgos, España. Electronic address: i.roberts.ma@gmail.com.
[Ti] Title:Paresia transitoria del nervio troclear tras angioplastia percutánea. Transient trochlear nerve palsy following percutaneous angioplasty.
[So] Source:Arch Soc Esp Oftalmol;, 2018 Feb 01.
[Is] ISSN:1989-7286
[Cp] Country of publication:Spain
[La] Language:eng; spa
[Ab] Abstract:CASE REPORT: A case is presented of a 63-year-old man who suffered a unilateral isolated trochlear nerve palsy with vertical diplopia following an elective radial coronary angiography and percutaneous coronary intervention, which resolved spontaneously within 2 months. DISCUSSION: Ophthalmoplegia following coronary percutaneous angioplasty is rare. Only internuclear ophthalmoplegia, III and VI cranial nerve palsy have been previously reported following percutaneous angioplasty. This is the first reported case of unilateral isolated trochlear nerve ophthalmoplegia following this procedure.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180205
[Lr] Last revision date:180205
[St] Status:Publisher

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[PMID]: 29325379
[Au] Autor:Kang XL; Wei Y
[Ad] Address:Xinhua Hospital Affiliated to the Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
[Ti] Title:[Pay attention to the clinical classification and individualized treatment of superior oblique palsy].
[So] Source:Zhonghua Yan Ke Za Zhi;53(12):881-884, 2017 Dec 11.
[Is] ISSN:0412-4081
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:Superior oblique palsy (SOP) has many anatomic variations, and the accompanied paralysis generalization could stimulate the secondary changes of other extra-ocular muscles. Therefore, the clinical manifestations of SOP can be various, and the surgical design is complicated and changeable. It is necessary to understand the clinical development, stages and types of SOP correctly, and to take into account the developmental characteristics of the superior oblique muscle and select the individualized treatment plan. In this article, the SOP manifestations, imaging features, clinical examination and personalized treatment options are discussed, in order to provide some reasonable treatment options for SOP surgery. .
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180111
[Lr] Last revision date:180111
[St] Status:In-Data-Review
[do] DOI:10.3760/cma.j.issn.0412-4081.2017.12.001

  3 / 818 MEDLINE  
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[PMID]: 29075763
[Au] Autor:Lee JE; Yang HK; Kim JH; Hwang JM
[Ad] Address:Department of Ophthalmology, Maryknoll Medical Center, Busan, Korea.
[Ti] Title:Ocular Torsion According to Trochlear Nerve Absence in Unilateral Superior Oblique Palsy.
[So] Source:Invest Ophthalmol Vis Sci;58(12):5526-5531, 2017 Oct 01.
[Is] ISSN:1552-5783
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Purpose: To investigate the relationship between objective ocular torsion and the presence or absence of the trochlear nerve in subjects with unilateral superior oblique palsy (SOP). Methods: A total of 159 subjects with congenital and acquired unilateral SOP were reviewed. Eighty-four subjects who had a normal trochlear nerve (present group) and 75 subjects without a trochlear nerve (absent group) were included. Cyclovertical motility parameters and objective ocular torsion were compared between groups, and factors related to ocular torsion were evaluated. Results: The degree of "net" excyclotorsion in the paretic eye was larger in the absent group compared to the present group (P = 0.002). The proportion of net excyclotorsion in the paretic eye was greater in the absent group (11% vs. 37%), while net incyclotorsion was greater in the present group (41% vs. 23%) (P < 0.001). Net excyclotorsion of the paretic eye was associated with absence of the trochlear nerve (P < 0.001) and smaller size of the paretic SO (P < 0.001). Net incyclotorsion of the paretic eye was related with a normal trochlear nerve (P = 0.005), larger size of the paretic SO (P = 0.002), and greater hypertropia during ipsilateral gaze (P = 0.024). Conclusions: The status of the trochlear nerve, paretic SO size, and hypertropia during ipsilateral gaze which reflects the tensile strength of the ipsilateral superior rectus, significantly contribute to ocular torsion in unilateral SOP.
[Mh] MeSH terms primary: Eye Movements/physiology
Ocular Motility Disorders/etiology
Oculomotor Muscles/physiopathology
Trochlear Nerve Diseases/congenital
Trochlear Nerve/abnormalities
[Mh] MeSH terms secundary: Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Ocular Motility Disorders/diagnosis
Ocular Motility Disorders/physiopathology
Oculomotor Muscles/innervation
Retrospective Studies
Trochlear Nerve/diagnostic imaging
Trochlear Nerve Diseases/complications
Trochlear Nerve Diseases/physiopathology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:IM
[Da] Date of entry for processing:171028
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-22452

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[PMID]: 28687220
[Au] Autor:Nash DL; Hatt SR; Leske DA; May L; Bothun ED; Mohney BG; Brodsky MC; Holmes JM
[Ad] Address:Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota; Department of Ophthalmology, Gundersen Health System, La Crosse, Wisconsin.
[Ti] Title:One- Versus Two-Muscle Surgery for Presumed Unilateral Fourth Nerve Palsy Associated With Moderate Angle Hyperdeviations.
[So] Source:Am J Ophthalmol;182:1-7, 2017 Oct.
[Is] ISSN:1879-1891
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: To compare 1-muscle vs 2-muscle surgery for moderate-angle hyperdeviations owing to presumed unilateral fourth nerve palsy. DESIGN: Retrospective chart review. METHODS: Seventy-three patients (aged 5-86 years) underwent either 1- or 2-muscle surgery at our institution for moderate hyperdeviation owing to presumed unilateral fourth nerve palsy, measuring 14-25 prism diopters (PD) in straight-ahead gaze at distance fixation. Six-week and 1-year motor success was defined as zero vertical deviation or 1-4 PD undercorrection at distance, overcorrection as any reversal of hypertropia, and undercorrection as >4 PD. Diplopia success was defined as no diplopia, or only rarely for distance straight ahead and reading. RESULTS: Twenty-eight patients underwent 1-muscle surgery, and 45 patients underwent 2-muscle surgery. Motor success was similar (64% vs 67%, P > .99 at 6 weeks; 47% vs 55%, P = .8 at 1 year, n = 46), but there were more undercorrections at 6 weeks with 1-muscle surgery (36% vs 16%, P = .09) and more overcorrections at 6 weeks with 2-muscle surgery (0% vs 18%, P = .02). Diplopia success was also somewhat similar between 1- and 2-muscle surgery at 6 weeks (73% vs 60%, P = .5) and 1 year (45% vs 59%, P = .5). CONCLUSION: For moderate-angle hyperdeviations owing to presumed unilateral fourth nerve palsy, there appears no clear advantage of 2-muscle surgery for motor outcomes. Diplopia success was similar between 1- and 2-muscle surgery, owing to a greater number of less symptomatic undercorrections with 1-muscle surgery and a smaller number of more symptomatic overcorrections with 2-muscle surgery.
[Mh] MeSH terms primary: Diplopia/surgery
Oculomotor Muscles/surgery
Ophthalmologic Surgical Procedures
Strabismus/surgery
Trochlear Nerve Diseases/surgery
[Mh] MeSH terms secundary: Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Diplopia/etiology
Diplopia/physiopathology
Female
Humans
Male
Middle Aged
Retrospective Studies
Strabismus/etiology
Strabismus/physiopathology
Trochlear Nerve Diseases/complications
Trochlear Nerve Diseases/physiopathology
Vision, Binocular/physiology
[Pt] Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171003
[Lr] Last revision date:171003
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170709
[St] Status:MEDLINE

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[PMID]: 28566142
[Au] Autor:Park JY; Ryu JC; Sung KB; Lee TK
[Ad] Address:Department of Neurology, Ulsan University Medical School, Ulsan University Hospital, Ulsan, Republic of Korea.
[Ti] Title:Three dimensional video-oculography and thin-slice magnetic resonance imaging in a patient with superior oblique myokymia.
[So] Source:J Neurol Sci;378:100-101, 2017 Jul 15.
[Is] ISSN:1878-5883
[Cp] Country of publication:Netherlands
[La] Language:eng
[Pt] Publication type:LETTER
[Em] Entry month:1706
[Cu] Class update date: 170601
[Lr] Last revision date:170601
[St] Status:In-Data-Review

  6 / 818 MEDLINE  
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[PMID]: 28534340
[Au] Autor:Kim JH; Hwang JM
[Ad] Address:Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
[Ti] Title:Imaging of Cranial Nerves III, IV, VI in Congenital Cranial Dysinnervation Disorders.
[So] Source:Korean J Ophthalmol;31(3):183-193, 2017 Jun.
[Is] ISSN:2092-9382
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:Congenital cranial dysinnervation disorders are a group of diseases caused by abnormal development of cranial nerve nuclei or their axonal connections, resulting in aberrant innervation of the ocular and facial musculature. Its diagnosis could be facilitated by the development of high resolution thin-section magnetic resonance imaging. The purpose of this review is to describe the method to visualize cranial nerves III, IV, and VI and to present the imaging findings of congenital cranial dysinnervation disorders including congenital oculomotor nerve palsy, congenital trochlear nerve palsy, Duane retraction syndrome, Möbius syndrome, congenital fibrosis of the extraocular muscles, synergistic divergence, and synergistic convergence.
[Mh] MeSH terms primary: Abducens Nerve/diagnostic imaging
Cranial Nerve Diseases/diagnosis
Duane Retraction Syndrome/complications
Magnetic Resonance Imaging/methods
Oculomotor Nerve/diagnostic imaging
Trochlear Nerve/diagnostic imaging
[Mh] MeSH terms secundary: Cranial Nerve Diseases/etiology
Duane Retraction Syndrome/diagnosis
Humans
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1710
[Cu] Class update date: 171012
[Lr] Last revision date:171012
[Js] Journal subset:IM
[Da] Date of entry for processing:170524
[St] Status:MEDLINE
[do] DOI:10.3341/kjo.2017.0024

  7 / 818 MEDLINE  
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[PMID]: 28494780
[Au] Autor:Teyssonneau D; Daste A; Dousset V; Hoepffner JL; Ravaud A; Gross-Goupil M
[Ad] Address:Department of Medical Oncology, Saint-André hospital, University Hospital-CHU Bordeaux, 1 Rue Jean Burguet, 33000, Bordeaux, France.
[Ti] Title:Metastatic non-muscle invasive bladder cancer with meningeal carcinomatosis: case report of an unexpected response.
[So] Source:BMC Cancer;17(1):323, 2017 May 11.
[Is] ISSN:1471-2407
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Non-muscle invasive bladder cancer (NMIBC) is usually treated with local therapy including transurethral resection of the bladder tumor and intravesical therapy depending on the stage of the tumor. NMIBC is a rarely a metastatic diseases with lymph node invasion in less of 10%. In the other hand meningeal carcinomatosis is a rare location for metastases with extremely poor outcomes. We described a case report of a patient presenting a metastatic disease to bones and meninges, several years after the treatment of NMIBC, which had been in complete response (CR) for 4 years after chemotherapy treatment. CASE PRESENTATION: A 63-years old men was treated by TURBT in 2008 for a high grade NMIBC, pT1b. Three years later he presented an acute binocular diplopy with right trochlear nerve paralysis, and labial hypoesthesia. Brain scan and MRI were performed finding a clivus infiltration and a pachymeningitis. A vertebral biopsy was performed finding an invasive carcinoma, CK7+/CK20+, TTF1-, PSA-, Thyroglobulin- and GATA3+. The metastatic event was in relation to the high grade NMIBC treated 3 years previously. Palliative chemotherapy was started with cisplatin gemcitabine. After 6 cycles and to date, 4 years later, the patient is therefore considered in complete response. CONCLUSION: Metastasis in non-muscle invasive urothelial carcinoma is rare. Meningeal carcinomatosis outcome is poor, usually appearing in widely metastatic and progressive cancers but also because most systemic agents fail to pass the blood-brain barrier and penetrate into the cerebrospinal fluid. We described an unexpected response with complete response after chemotherapy for meningeal carcinomatosis of non muscle invasive urothelial carcinoma.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1705
[Cu] Class update date: 170515
[Lr] Last revision date:170515
[St] Status:In-Process
[do] DOI:10.1186/s12885-017-3309-2

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[PMID]: 28434965
[Au] Autor:Nesvick CL; Perry A; Graffeo CS; Raghunathan A; Hammack JE; Van Gompel JJ
[Ad] Address:Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
[Ti] Title:Trochlear Schwannoma Presenting with Isolated Trigeminal Neuralgia.
[So] Source:World Neurosurg;103:951.e13-951.e20, 2017 Jul.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Schwannomas arising from the cranial nerves controlling extraocular eye movements are very rare and usually present with some degree of diplopia. CASE PRESENTATION: We report a 50-year-old woman who presented with isolated left-sided trigeminal neuralgia of 6 months' duration. Imaging demonstrated a homogeneously enhancing mass in the left ambient cistern, and the patient was brought to the operating room for resection. A retrosigmoid approach was used, and the mass was directly visualized arising from the trochlear nerve and compressing the dorsal root entry zone of the trigeminal nerve. A gross total resection of the mass was achieved, and microvascular decompression of the trigeminal nerve was performed. The tumor was pathologically confirmed as a schwannoma. At 3-month follow-up, the patient's facial pain was resolved, and her extraocular eye movements were intact. CONCLUSIONS: A total of 32 pathology-confirmed cases of trochlear schwannoma have been previously reported in the English-language literature. Most of these tumors arose from the cisternal segment of the nerve, and most patients presented with frank trochlear nerve palsy on exam. We report the first case of trochlear schwannoma presenting with isolated trigeminal neuralgia.
[Mh] MeSH terms primary: Cranial Nerve Neoplasms/complications
Neurilemmoma/complications
Trigeminal Neuralgia/etiology
Trochlear Nerve Diseases/complications
[Mh] MeSH terms secundary: Cranial Nerve Neoplasms/diagnostic imaging
Cranial Nerve Neoplasms/pathology
Cranial Nerve Neoplasms/surgery
Female
Humans
Magnetic Resonance Imaging
Microvascular Decompression Surgery
Middle Aged
Neurilemmoma/diagnostic imaging
Neurilemmoma/pathology
Neurilemmoma/surgery
Neurosurgical Procedures
Trigeminal Neuralgia/surgery
Trochlear Nerve Diseases/diagnostic imaging
Trochlear Nerve Diseases/pathology
Trochlear Nerve Diseases/surgery
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170925
[Lr] Last revision date:170925
[Js] Journal subset:IM
[Da] Date of entry for processing:170425
[St] Status:MEDLINE

  9 / 818 MEDLINE  
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[PMID]: 28366647
[Au] Autor:Bata BM; Leske DA; Holmes JM
[Ad] Address:Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
[Ti] Title:Adjustable Bilateral Superior Oblique Tendon Advancement for Bilateral Fourth Nerve Palsy.
[So] Source:Am J Ophthalmol;178:115-121, 2017 Jun.
[Is] ISSN:1879-1891
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: Bilateral fourth nerve palsy may be symmetric or asymmetric with combined vertical and excylotropic deviations and so there may be an advantage to independent adjustment of vertical and torsional components. We report a surgical technique that allows such independent adjustment. DESIGN: Retrospective interventional case series. METHODS: Fifteen patients, aged 17-73 years, underwent adjustable bilateral superior oblique tendon advancements for bilateral fourth nerve palsy: 11 symmetric (≤2 prism diopters [pd] hyperdeviation in straight-ahead gaze) and 4 asymmetric. Motor alignment was assessed with double Maddox rods and prism and alternate cover tests preoperatively, pre- and postadjustment, and 6 weeks postoperatively. RESULTS: Preoperative torsion ranged from 7 to 30 degrees excyclotropia (mean 17 ± 7 degrees) and hyperdeviation from 0 to 10 pd. Preadjustment torsion ranged from 5 degrees excyclotropia to 40 degrees incyclotropia, and hyperdeviation from 0 to 8 pd. Twelve of the 15 patients (80%) were adjusted to a target of 0 pd hyperphoria and 10 degrees incyclotropia (actual mean 9 degrees incyclotropia, range 2-13 degrees incyclotropia). At 6 weeks postoperatively there was expected excyclodrift (to mean 4 degrees excyclotropia, range 0 degrees incyclotropia to 15 degrees excyclotropia), but 13 (87%) had 5 degrees or less excyclotropia and 14 (93%) had 2 pd or less hyperdeviation. Mean torsional correction from preoperative to preadjustment was 31 ± 14 degrees (P < .0001), and from preoperative to 6 weeks was 13 ± 6 degrees (P < .0001). CONCLUSIONS: Adjustable bilateral superior oblique tendon advancement allows independent control of torsional and vertical components of the deviation, and therefore may be useful in cases of bilateral superior oblique palsy.
[Mh] MeSH terms primary: Eye Movements/physiology
Oculomotor Muscles/surgery
Ophthalmologic Surgical Procedures/methods
Strabismus/surgery
Tendons/surgery
Trochlear Nerve Diseases/surgery
Vision, Binocular/physiology
[Mh] MeSH terms secundary: Adolescent
Adult
Aged
Female
Follow-Up Studies
Humans
Male
Middle Aged
Oculomotor Muscles/physiopathology
Postoperative Period
Strabismus/etiology
Strabismus/physiopathology
Time Factors
Trochlear Nerve Diseases/complications
Trochlear Nerve Diseases/physiopathology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1707
[Cu] Class update date: 170721
[Lr] Last revision date:170721
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170404
[St] Status:MEDLINE

  10 / 818 MEDLINE  
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[PMID]: 28292276
[Au] Autor:Lee DC; Lee SY
[Ad] Address:Department of Ophthalmology, Keimyung University Dongsan Medical Center, Keimyung University school of Medicine, Daegu, 41931, South Korea.
[Ti] Title:Effect of modified graded recession and anteriorization on unilateral superior oblique palsy: a retrospective study.
[So] Source:BMC Ophthalmol;17(1):27, 2017 Mar 14.
[Is] ISSN:1471-2415
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Several inferior oblique (IO) weakening methods exist for correction of superior oblique palsy (SOP). A previously reported method involved recession and anteriorization according to IO overaction (IOOA) grade, which might be subjective and cause upgaze limitation and opposite vertical strabismus. Therefore, this study attempted to examine the efficacy of modified graded recession and anteriorization of the IO muscle in correction of unilateral SOP without resulting in upgaze limitation or opposite vertical strabismus. METHODS: A total of 26 patients (male, 16; female, 10; age: 3-40 years) with SOP and head tilt or diplopia underwent modified graded recession and anteriorization. Patients were grouped by the position at which the IO muscle was attached inferior/temporal to the lateral border of the inferior rectus (IR) as follows: (1) 7.0/2.0 mm (4 patients), (2) 6.0/2.0 mm (3 patients), (3) 5.0/2.0 mm (3 patients), (4) 4.0/2.0 mm (11 patients), (5) 3.0/0.0 mm (2 patients), and (6) 2.0/0.0 mm (3 patients). Recession and anteriorization were matched to vertical deviation in the primary position at far distance. Remaining diplopia, head tilt, vertical deviation (≤3 prism diopter (PD), excellent; 4-7 PD, good; and ≥ 8 PD, poor), upgaze limitation, and opposite vertical strabismus were evaluated. RESULTS: The average pre and postoperative 1-year vertical deviation angles in the primary position at far distance were 15.0 ± 5.6 PD and 1.2 ± 2.0 PD, respectively. At 1 year post-surgery, the vertical deviation angles were reduced by 6.8-21.0 PD from those at baseline. Few patients exhibited remaining head tilt, diplopia, upgaze limitation, or opposite vertical strabismus. Correction of hypertropia was excellent in 22 and good in 4 patients. CONCLUSIONS: Modified graded recession and anteriorization of the IO muscle is an effective surgical method for treating unilateral SOP. It exhibits good results and reduces the incidence of opposite vertical strabismus.
[Mh] MeSH terms primary: Eye Movements/physiology
Oculomotor Muscles/surgery
Ophthalmologic Surgical Procedures/methods
Trochlear Nerve Diseases/surgery
Vision, Binocular
[Mh] MeSH terms secundary: Adolescent
Adult
Child
Child, Preschool
Diplopia/etiology
Diplopia/physiopathology
Diplopia/surgery
Female
Follow-Up Studies
Humans
Male
Oculomotor Muscles/physiopathology
Retrospective Studies
Time Factors
Trochlear Nerve Diseases/physiopathology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170816
[Lr] Last revision date:170816
[Js] Journal subset:IM
[Da] Date of entry for processing:170316
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0422-6


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