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[PMID]: 24443117
[Au] Autor:Barry RL; Gore JC
[Ad] Address:Vanderbilt University Institute of Imaging Science, Nashville, Tennessee; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
[Ti] Title:Enhanced phase regression with Savitzky-Golay filtering for high-resolution BOLD fMRI.
[So] Source:Hum Brain Mapp;35(8):3832-40, 2014 Aug.
[Is] ISSN:1097-0193
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Phase regression exploits the temporal evolution of phase in individual voxels to suppress blood oxygenation level dependent (BOLD) signal fluctuations caused by larger vessels and draining veins while preserving signal changes from microvascular effects. However, this process does not perform well when phase time series have low signal-to-noise ratios because of high levels of physiological noise. We demonstrate that Savitzky-Golay filters may be used to recover the underlying change in phase and completely restore the efficacy of phase regression. We do not make a priori assumptions regarding phase evolution and perform a data-driven exploration of parameter space to select the Savitzky-Golay filter parameters that minimize temporal variance in each voxel after phase regression. This approach is shown to work well on data acquired with single-shot and multi-shot pulse sequences, and should therefore be useful for both human and animal gradient-echo fMRI at high spatial resolutions at high fields. The ability to improve the spatial specificity of BOLD activation may be especially advantageous for clinical applications of fMRI that rely upon the accuracy of individual subject's activation maps to assist with presurgical planning and clinical decision-making. Enhanced phase regression with Savitzky-Golay filtering may also find other uses in analyses of resting state functional connectivity.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Entry month:1407
[Cu] Class update date: 150117
[Lr] Last revision date:150117
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1002/hbm.22440

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[PMID]: 25249421
[Au] Autor:Bosemani T; Orman G; Hergan B; Carson KA; Huisman TA; Poretti A
[Ad] Address:Section of Pediatric Neuroradiology, Division of Pediatric Radiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Charlotte R. Bloomberg Children's Center, Sheikh Zayed Tower, Room 4174, 1800 Orleans Street, Baltimore, MD, 21287-0842, USA.
[Ti] Title:Achondroplasia in children: correlation of ventriculomegaly, size of foramen magnum and jugular foramina, and emissary vein enlargement.
[So] Source:Childs Nerv Syst;31(1):129-33, 2015 Jan.
[Is] ISSN:1433-0350
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:PURPOSE: Achondroplasia is a skeletal dysplasia with diminished growth of the skull base secondary to defective enchondral bone formation. This leads to narrowing of the foramen magnum and jugular foramina, which further leads to ventricular dilatation and prominence of the emissary veins. The primary goal of our study was to determine a correlation between the degree of ventricular dilatation, jugular foramina and foramen magnum narrowing, as well as emissary vein enlargement. METHODS: Conventional T2-weighted MR images were evaluated for surface area of the foramen magnum and jugular foramina, ventricular dilatation, and emissary veins enlargement in 16 achondroplasia patients and 16 age-matched controls. Ratios were calculated for the individual parameters using median values from age-matched control groups to avoid age as a confounder. RESULTS: Compared to age-matched controls, in children with achondroplasia, the surface area of the foramen magnum (median 0.50 cm(2), range 0.23-1.37 cm(2) vs. 3.14 cm(2), 1.83-6.68 cm(2), p < 0.001) and jugular foramina (median 0.02 cm(2), range 0-0.10 cm(2) vs. 0.21 cm(2), 0.03-0.61 cm(2), p < 0.001) were smaller, whereas ventricular dilatation (0.28, 0.24-0.4 vs. 0.26, 0.21-0.28, p < 0.001) and enlargement of emissary veins (6, 0-11 vs. 0, p < 0.001) were higher. Amongst the patients, Spearman correlation and multiple regression analysis did not reveal correlation for severity between the individual parameters. CONCLUSIONS: Our study suggests that in children with achondroplasia, (1) the variation in ventricular dilatation may be related to an unquantifiable interdependent relationship of emissary vein enlargement, venous channel narrowing, and foramen magnum compression and (2) stable ventricular size facilitated by interdependent factors likely obviates the need for ventricular shunt placement.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1007/s00381-014-2559-4

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[PMID]: 24472021
[Au] Autor:Mostafa T; Rashed LA; Zeidan AS; Hosni A
[Ad] Address:Department of Andrology and Sexology, Faculty of Medicine, Cairo University, Cairo, Egypt.
[Ti] Title:Glutathione-S-transferase-oxidative stress relationship in the internal spermatic vein blood of infertile men with varicocele.
[So] Source:Andrologia;47(1):47-51, 2015 Feb.
[Is] ISSN:1439-0272
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:This study aimed to assess glutathione-S-transferase (GST) enzyme- oxidative stress (OS) relationship in the internal spermatic vein (ISV) of infertile men associated with varicocele (Vx). Ninety five infertile oligoasthenoteratozoospemic (OAT) men associated with Vx were subjected to history taking, clinical examination and semen analysis. During inguinal varicocelectomy, GST, malondialdehyde (MDA) and glutathione peroxidase (GPx) were estimated in the blood samples drawn from ISV and median cubital veins. The mean levels of GST, GPx were significantly decreased and the mean level of GPx was significantly increased in the ISV compared with the peripheral blood. The mean level of GST and GPx in the ISV was significantly decreased, and the mean level of MDA was significantly increased in Vx grade III compared with Vx grade II cases. There was nonsignificant difference in the mean level of GST in the ISV in unilateral Vx cases compared with bilateral Vx cases. There was significant positive correlation of GST with sperm count, sperm motility, GPx and significant negative correlation with sperm abnormal forms, MDA. It is concluded that ISV of infertile men associated with Vx has decreased levels of GST compared with peripheral venous circulation that is correlated with both OS and Vx grade.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1111/and.12234

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[PMID]: 25133308
[Au] Autor:Weaver KN; Wang D; Cnota J; Gardner N; Stabley D; Sol-Church K; Gripp KW; Witte DP; Bove KE; Hopkin RJ
[Ad] Address:1 Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
[Ti] Title:Early-Lethal Costello Syndrome Due to Rare HRAS Tandem Base Substitution (c.35_36GC>AA; p.G12E)-Associated Pulmonary Vascular Disease.
[So] Source:Pediatr Dev Pathol;17(6):421-30, 2014 Nov-Dec.
[Is] ISSN:1093-5266
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Costello syndrome is a rare, autosomal-dominant syndrome caused by activating missense mutations in the Harvey rat sarcoma viral oncogene homolog (HRAS), most often p.G12S. Several rare mutations have consistently been associated with a more severe phenotype that is often lethal in infancy. Cause of death is most often respiratory failure, with hypertrophic cardiomyopathy playing a significant role in morbidity. Impaired fibroblast elastogenesis is thought to contribute to the Costello phenotype, but reports of histologic evidence of disordered elastogenesis at autopsy are limited. We report a patient with Costello syndrome due to a rare tandem base substitution (c.35_36GC>AA) resulting in the p.G12E missense change. The proband died at the age of 3 months from respiratory failure, with minimal evidence of cardiomyopathy. The autopsy disclosed pulmonary vascular dysplasia affecting small arteries and veins associated with abnormal elastin distribution in tortuous dilated arteries and veins, with nonuniform wall thickness and semiobstructive lesions at artery branch points typical of early pulmonary hypertensive vascular disease. Elastic fibers in the dermis were abnormally short and fragmented. This case suggests that disordered elastogenesis in the pulmonary vasculature and undiagnosed (or underdiagnosed) pulmonary hypertension may contribute to morbidity in patients with Costello syndrome.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Cu] Class update date: 150116
[Lr] Last revision date:150116
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.2350/14-05-1488-OA.1

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[PMID]: 25587351
[Au] Autor:Choi SY; Kwak BK; Seo T
[Ad] Address:Department of Radiology and Medical Research Institute, School of Medicine, Ewha Womans University, 1071 Anyangcheon-ro, Yangcheon-gu, Seoul 158-710, Republic of Korea.
[Ti] Title:Mathematical modeling of radiofrequency ablation for varicose veins.
[So] Source:Comput Math Methods Med;2014:485353, 2014.
[Is] ISSN:1748-6718
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We present a three-dimensional mathematical model for the study of radiofrequency ablation (RFA) with blood flow for varicose vein. The model designed to analyze temperature distribution heated by radiofrequency energy and cooled by blood flow includes a cylindrically symmetric blood vessel with a homogeneous vein wall. The simulated blood velocity conditions are U = 0, 1, 2.5, 5, 10, 20, and 40 mm/s. The lower the blood velocity, the higher the temperature in the vein wall and the greater the tissue damage. The region that is influenced by temperature in the case of the stagnant flow occupies approximately 28.5% of the whole geometry, while the region that is influenced by temperature in the case of continuously moving electrode against the flow direction is about 50%. The generated RF energy induces a temperature rise of the blood in the lumen and leads to an occlusion of the blood vessel. The result of the study demonstrated that higher blood velocity led to smaller thermal region and lower ablation efficiency. Since the peak temperature along the venous wall depends on the blood velocity and pullback velocity, the temperature distribution in the model influences ablation efficiency. The vein wall absorbs more energy in the low pullback velocity than in the high one.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Cu] Class update date: 150116
[Lr] Last revision date:150116
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1155/2014/485353

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[PMID]: 25587472
[Au] Autor:Podduturi V; Armstrong-Briley DR; Guileyardo JM
[Ad] Address:Department of Pathology, Baylor University Medical Center, Dallas, TX, USA.
[Ti] Title:Sudden Death by Pulmonary Thromboembolism due to a Large Uterine Leiomyoma with a Parasitic Vein to the Mesentery.
[So] Source:Case Rep Obstet Gynecol;2014:181265, 2014.
[Is] ISSN:2090-6684
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium. Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported. We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE. The association of large pelvic masses with venous thrombosis has clinical implications, since prophylactic surgery could be life-saving.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Cu] Class update date: 150116
[Lr] Last revision date:150116
[Da] Date of entry for processing:150114
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1155/2014/181265

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[PMID]: 25584205
[Au] Autor:Nayak B S; Sirasanagandla SR; Aithal P A; Guru A; S S
[Ad] Address:Professor and Head, Department of Anatomy, Melaka Manipal Medical College (Manipal Campus), Manipal University , Madhav Nagar, Manipal, Karnataka, India ....
[Ti] Title:Unusual infra-clavicular venous circle - a case report.
[So] Source:J Clin Diagn Res;8(11):AD01-2, 2014 Nov.
[Is] ISSN:2249-782X
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Currently, numerous invasive procedures are preferred in cephalic vein (CV) and axillary vein (AV) than other veins in the neck. Anatomical variations of these veins in the axilla and delto-pectoral region may result in failure and postoperative complications of the procedures. A thorough knowledge of possible variations of AV and CV may immensely contribute to the success of any such procedures where the veins are involved. We report the variations of the CV, tributaries of AV and median cubital vein. We observed a venous circle formed by the tributaries of AV in the infra-clavicular region, deep to the pectoral muscles. Cephalic vein joined proximal end of venous circle just before ending into AV. Further, duplication of the median cubital vein was observed.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1501
[Cu] Class update date: 150116
[Lr] Last revision date:150116
[Da] Date of entry for processing:150113
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.7860/JCDR/2014/9396.5113

  8 / 158191 MEDLINE  
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[PMID]: 24708611
[Au] Autor:McDonald-Burrows Z; Davies R; Goode E; Clarke C; Jackson J; Seckl M; Savage P
[Ti] Title:Haemoptysis from a pulmonary arteriovenous malformation in a post molar pregnancy gestational trophoblast tumour patient managed by radiological embolisation: a case report.
[So] Source:J Med Case Rep;8:117, 2014.
[Is] ISSN:1752-1947
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Gestational trophoblastic tumours are a rare form of malignancy, which in the majority of cases arise from abnormal trophoblast cells formed in a complete molar pregnancy. These tumours are extremely sensitive to chemotherapy and high cure rates approaching 100% can be expected. The disease is usually limited to the uterus where the abnormal trophoblast proliferation and human chorionic production can lead to vascular changes including the formation of arteriovenous malformations. CASE PRESENTATION: We describe the case of a 28-year-old Caucasian woman who presented to the United Kingdom's Gestational Trophoblast Tumour Service with rising human chorionic gonadotropin levels following a uterine evacuation for a complete molar pregnancy. She was commenced on chemotherapy but subsequently reported two episodes of haemoptysis. Computed tomography imaging demonstrated findings consistent with a pulmonary arteriovenous malformation, probably due to a small pulmonary metastasis, complicated by recent haemorrhage. These findings were confirmed on emergency pulmonary arteriography, and the pulmonary arteriovenous malformation was successfully embolised. CONCLUSIONS: Arteriovenous malformations secondary to gestational trophoblastic tumours at metastatic sites have only been reported in a very limited number of cases. When significant bleeding occurs, as in this case of a pulmonary lesion, urgent referral for embolisation is indicated.
[Mh] MeSH terms primary: Arteriovenous Malformations/therapy
Embolization, Therapeutic/methods
Hemoptysis/therapy
Hydatidiform Mole/drug therapy
Lung Neoplasms/drug therapy
Uterine Neoplasms/drug therapy
[Mh] MeSH terms secundary: Adult
Angiography
Arteriovenous Malformations/etiology
Arteriovenous Malformations/radiography
Female
Hemoptysis/etiology
Humans
Hydatidiform Mole/complications
Hydatidiform Mole/secondary
Lung Neoplasms/complications
Lung Neoplasms/secondary
Pregnancy
Pulmonary Artery/abnormalities
Pulmonary Artery/radiography
Pulmonary Veins/abnormalities
Pulmonary Veins/radiography
Tomography, X-Ray Computed
Uterine Neoplasms/pathology
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[Da] Date of entry for processing:140624
[St] Status:MEDLINE
[do] DOI:10.1186/1752-1947-8-117

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[PMID]: 24885801
[Au] Autor:Hu H; Cai Y; Wang C; Yang C; Duan Z; Zhang J; Xin S
[Ad] Address:Division of Vascular and Thyroid Surgery, Department of Surgery, The First Affiliated Hospital, China Medical University, Shenyang 110001, China. hu_haidi@hotmail.com.
[Ti] Title:Successful treatment of posttraumatic phlegmasia cerulea dolens by reconstructing the external iliac vein: a case report.
[So] Source:J Med Case Rep;8:149, 2014.
[Is] ISSN:1752-1947
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Phlegmasia cerulea dolens is a rare condition caused by complete venous occlusion leading to impaired arterial flow. To prevent progression to limb gangrene, prompt diagnosis and treatment initiation are paramount. Here we report a rare case of posttraumatic phlegmasia cerulea dolens after ligation of the iliac vein to save the patient's life, with successful treatment by reconstructing the external iliac vein. This is the first report of posttraumatic phlegmasia cerulea dolens induced by iliac vein ligation. CASE PRESENTATION: A 49-year-old Chinese man was admitted to a local hospital for severe knife trauma with massive intraperitoneal bleeding. During exploratory laparotomy, he was diagnosed with traumatic rupture of his left external iliac vein without injury to the iliac artery. The proximal and distal parts of his injured external iliac vein were ligated to control the bleeding and rescue him, but his left leg quickly became severe swollen, cyanotic and pulseless. He was diagnosed with posttraumatic phlegmasia cerulea dolens after being transferred to our university hospital. After a retrievable filter was placed in his inferior vena cava via his right femoral vein, he underwent reopening of his abdomen followed by successful surgical reconstruction of his left iliac vein. He was treated with anticoagulation therapy postoperatively and his signs and symptoms improved markedly. He was discharged in a stable condition, with nearly full resolution of symptoms, 35 days after the operation. CONCLUSIONS: Our case demonstrates that ligation of an injured iliac vein may induce phlegmasia cerulea dolens in a posttraumatic scenario; prompt reconstruction of the iliac vein to restore the venous drainage is an effective treatment for phlegmasia cerulea dolens with impending gangrene.
[Mh] MeSH terms primary: Iliac Vein/injuries
Vascular Diseases/etiology
Vascular Surgical Procedures/methods
[Mh] MeSH terms secundary: Humans
Iliac Vein/surgery
Ligation
Male
Middle Aged
Vascular Diseases/surgery
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[Da] Date of entry for processing:140609
[St] Status:MEDLINE
[do] DOI:10.1186/1752-1947-8-149

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[PMID]: 24779707
[Au] Autor:Kong H; Chen S; Wen X
[Ad] Address:Department of Anesthesiology, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, PR China. hzkhy@163.com.
[Ti] Title:Suture of the right internal jugular vein catheter in a mitral valve replacement: a case report.
[So] Source:J Med Case Rep;8:129, 2014.
[Is] ISSN:1752-1947
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:INTRODUCTION: Central venous catheterization can be necessary for patients undergoing a cardiac operation. Accidental suturing of the catheter to the heart is a rare complication that is difficult to correct; excessive traction force on the central venous catheter can lead to heart breakage or even death. CASE PRESENTATION: We describe the case of a 56-year-old Han Chinese woman who was scheduled to undergo mitral valve replacement. The central venous catheter placed into her right internal jugular vein was accidentally sutured to the left atrial suture line during the operation. The stuck catheter was successfully removed without having to perform a cardiopulmonary bypass. CONCLUSIONS: Attaching a catheter to the heart by cardiac sutures can occur when the tip of the catheter locates directly above the atrial-caval junction. Care should be taken when closing the cephalad end of a left atrial incision in a mitral valve replacement. Although rare, accidental suturing of the central venous catheter must be kept in mind, and an approach should be chosen to remove the catheter that best avoids additional insult to the heart function.
[Mh] MeSH terms primary: Catheterization, Central Venous/adverse effects
Heart Valve Prosthesis Implantation/adverse effects
Jugular Veins
Mitral Valve Stenosis/surgery
Suture Techniques/adverse effects
[Mh] MeSH terms secundary: Catheters
Female
Humans
Middle Aged
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1501
[Js] Journal subset:IM
[Da] Date of entry for processing:140603
[St] Status:MEDLINE
[do] DOI:10.1186/1752-1947-8-129


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