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[PMID]: 25634722
[Au] Autor:Alexander MD; Cooke DL; Nelson J; Guo DE; Dowd CF; Higashida RT; Halbach VV; Lawton MT; Kim H; Hetts SW
[Ad] Address:From the Department of Radiology (M.D.A.), University of Washington, Seattle, Washington....
[Ti] Title:Association between Venous Angioarchitectural Features of Sporadic Brain Arteriovenous Malformations and Intracranial Hemorrhage.
[So] Source:AJNR Am J Neuroradiol;36(5):949-52, 2015 May.
[Is] ISSN:1936-959X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND AND PURPOSE: Intracranial hemorrhage is the most serious outcome for brain arteriovenous malformations. This study examines associations between venous characteristics of these lesions and intracranial hemorrhage. MATERIALS AND METHODS: Statistical analysis was performed on a prospectively maintained data base of brain AVMs evaluated at an academic medical center. DSA, CT, and MR imaging studies were evaluated to classify lesion side, drainage pattern, venous stenosis, number of draining veins, venous ectasia, and venous reflux. Logistic regression analyses were performed to identify the association of these angiographic features with intracranial hemorrhage of any age at initial presentation. RESULTS: Exclusively deep drainage (OR, 3.42; 95% CI, 1.87-6.26; P < .001) and a single draining vein (OR, 1.98; 95% CI, 1.26-3.08; P = .002) were associated with hemorrhage, whereas venous ectasia (OR, 0.52; 95% CI, 0.34-0.78; P = .002) was inversely associated with hemorrhage. CONCLUSIONS: Analysis of venous characteristics of brain AVMs may help determine their prognosis and thereby identify lesions most appropriate for treatment.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3174/ajnr.A4224

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[PMID]: 25572952
[Au] Autor:Krings T; Kim H; Power S; Nelson J; Faughnan ME; Young WL; terBrugge KG; Brain Vascular Malformation Consortium HHT Investigator Group
[Ad] Address:From the Division of Neuroradiology (T.K., S.P., K.G.t.B.), Department of Medical Imaging Division of Neurosurgery (T.K.), Department of Surgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada Timo.Krings@uhn.ca....
[Ti] Title:Neurovascular manifestations in hereditary hemorrhagic telangiectasia: imaging features and genotype-phenotype correlations.
[So] Source:AJNR Am J Neuroradiol;36(5):863-70, 2015 May.
[Is] ISSN:1936-959X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND AND PURPOSE: Hereditary hemorrhagic telangiectasia is an autosomal dominant disease that presents in 10%-20% of patients with various brain vascular malformations. We aimed to report the radiologic features (phenotype) and the genotype-phenotype correlations of brain vascular malformations in hereditary hemorrhagic telangiectasia. MATERIALS AND METHODS: Demographic, clinical, genotypic, and imaging information of 75 patients with hereditary hemorrhagic telangiectasia with brain arteriovenous malformations enrolled in the Brain Vascular Malformation Consortium from 2010 to 2012 were reviewed. RESULTS: Nonshunting, small, superficially located conglomerates of enhancing vessels without enlarged feeding arteries or draining veins called "capillary vascular malformations" were the most commonly observed lesion (46 of 75 patients; 61%), followed by shunting "nidus-type" brain AVMs that were typically located superficially with a low Spetzler-Martin Grade and a small size (32 of 75 patients; 43%). Direct high-flow fistulous arteriovenous shunts were present in 9 patients (12%). Other types of vascular malformations (dural AVF and developmental venous anomalies) were present in 1 patient each. Multiplicity of vascular malformations was seen in 33 cases (44%). No statistically significant correlation was observed between hereditary hemorrhagic telangiectasia gene mutation and lesion type or lesion multiplicity. CONCLUSIONS: Depending on their imaging features, brain vascular malformations in hereditary hemorrhagic telangiectasia can be subdivided into brain AVF, nidus-type AVM, and capillary vascular malformations, with the latter being the most common phenotype in hereditary hemorrhagic telangiectasia. No genotype-phenotype correlation was observed among patients with this condition.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.3174/ajnr.A4210

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[PMID]: 25934795
[Au] Autor:Bas Y; Güney G; Uzbay P; Zobaci E; Ardali S; Özkan AT
[Ad] Address:Department of Pathology, Hitit University, Faculty of Medicine, Çorum, Turkey....
[Ti] Title:Colon Perforation and Budd-Chiari Syndrome in Behçet's Disease.
[So] Source:Am J Case Rep;16:262-7, 2015.
[Is] ISSN:1941-5923
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Background Behçet's disease is a chronic inflammatory disease involving multiple systems, with vasculitis being the most important pathological feature. Multiple colon perforations are thought to be secondary to vasculitis and they occur in patients with ulcers. These may be encountered within the entire colon but most commonly in the ileocecal region. Intestinal perforation and Budd-Chiari syndrome are infrequent in Behçet's disease, and are associated with high mortality and morbidity. Budd-Chiari syndrome results from occlusion of either hepatic veins or adjacent inferior vena cava, or both. Case Report We report a patient with Behçet's disease having multiple perforations in the transverse colon, descending colon, and sigmoid colon. The patient also had Budd-Chiari syndrome due to inferior vena cava thrombosis extending into the right and middle hepatic vein. Our observations are presented with a review of the literature. Conclusions In Behçet's disease, treatment of colon perforation necessitates urgent surgery, whereas management of Budd-Chiari syndrome is directed towards the underlying cause. Behçet's disease, as a chronic multisystemic disease with various forms of vasculitis, is resistant to medical and surgical treatment. Prognosis is worse in Behçet's disease with colon perforation than that in Budd-Chiari syndrome alone.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Cu] Class update date: 150515
[Lr] Last revision date:150515
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.12659/AJCR.892757

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[PMID]: 25522491
[Au] Autor:Tinghui Z; Xiaorong M; Yingying H; Huiping C; Yan X; Tianxiang O
[Ti] Title:[Effects of propranolol on proliferation of hemangioma-derived mesenchymal stem cells ].
[So] Source:Zhonghua Zheng Xing Wai Ke Za Zhi;30(5):373-7, 2014 Sep.
[Is] ISSN:1009-4598
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To explore the new mechanism of propranolol for treatment of hemangioma and the effects of propranolol on proliferation of hemangioma-derived mesenchymal stem cells ( Hem- MSCs). METHODS: We isolated Hem-MSCs from hemangioma in the proliferating phase by their selective adhesion to plastic culture dishes. Immunofluorescence staining was used to examine the expression of marker antigens in Hem-MSCs. Human umbilical vein endothelial cells(HUVECs) were used as control. Indiuction of multi-lineage differentiation including osteogenesis and adipogeneis was performed with appropriate medium to identify the multi-lineage differentiation potential. MTT cell counting was used to observe the effects of different concentrations of propranolol on proliferation of Hem-MSCs. RESULTS: Hem- MSCs were fibroblast-like morphology. All of them expressed vimentin, most expressed α-SMA,CD133, some expressed Glutl, and none of them expressed VEGF. Osteogenic, adipogenic differentiations of Hem- MSCs were induced successfully. Effects of low concentration of propranolol on proliferation of Hem-MSCs were not obvious, while high concentration of propranolol can inhibit the proliferation of Hem-MSCs. CONCLUSIONS: The cells we isolated from hemangioma are Hem-MSCs. High concentration of propranolol can inhibit the proliferation of Hem-MSCs.
[Mh] MeSH terms primary: Cell Proliferation/drug effects
Hemangioma/pathology
Mesenchymal Stromal Cells/drug effects
Propranolol/pharmacology
[Mh] MeSH terms secundary: Adipogenesis
Antigens/metabolism
Cell Differentiation
Cells, Cultured
Endothelium, Vascular/cytology
Fibroblasts/cytology
Humans
Mesenchymal Stromal Cells/cytology
Mesenchymal Stromal Cells/metabolism
Osteogenesis
Umbilical Veins
Vimentin/metabolism
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Name of substance:0 (Antigens); 0 (Vimentin); 9Y8NXQ24VQ (Propranolol)
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:141219
[St] Status:MEDLINE

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[PMID]: 25399902
[Au] Autor:Lu J; Cui X; Li N
[Ad] Address:Department of Anesthesia, Xi'an Central Hospital Affiliated to Medical College of Xi'an Jiaotong University, Xi'an 710003, Shaanxi, China.
[Ti] Title:[Application of new way of axillary vein insertion in the emergency and critical patients].
[So] Source:Zhonghua Wei Zhong Bing Ji Jiu Yi Xue;26(11):839-40, 2014 Nov.
[Is] ISSN:2095-4352
[Cp] Country of publication:China
[La] Language:chi
[Mh] MeSH terms primary: Axillary Vein/surgery
Critical Care/methods
Emergency Medical Services/methods
[Mh] MeSH terms secundary: Humans
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:141117
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.2095-4352.2014.11.015

  6 / 159878 MEDLINE  
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[PMID]: 24941757
[Au] Autor:Jiang Q; Wang Y; Yang L; Jiang Z
[Ti] Title:[Clinical application of veno-arteriolization of finger lateral vein for repairing severed finger tips].
[So] Source:Zhonghua Zheng Xing Wai Ke Za Zhi;30(2):93-5, 2014 Mar.
[Is] ISSN:1009-4598
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To investigate effect of veno-arteriolization of finger lateral vein for repairing severed finger tips. METHODS: From March 2007 to April 2012, 20 patients with severed finger tips were treated with veno-arteriolization of finger lateral vein after failure in anastomosing artery of finger over times. During operation, the dominant digital artery at proximal end and the dominant finger lateral vein at distal end was anastomosed as the blood supply, the non-superiorty finger lateral vein was anastomosed as the blood drainage. RESULTS: All flaps survived completely and achieved primary healing. 18 patients were successfully followed up for 6 to 12 months with satisfactory appearance and nail growth. Finger pulp was plump with good flexibility. The average length of nail was (15.6 +/- 2.7) mm and the average motion of DIP joint was (62 +/- 4) degrees. The average two point discrimination was (4.6 +/- 0.3) mm and the average sensation measurement was S3+. CONCLUSION: The veno-arteriolization of finger lateral vein is a valuable method for repairing severed finger tips, which can promote nail growth, and restore fingers motion and sensation.
[Mh] MeSH terms primary: Finger Injuries/surgery
Fingers/blood supply
[Mh] MeSH terms secundary: Anastomosis, Surgical/methods
Arteries/surgery
Humans
Reconstructive Surgical Procedures/methods
Skin Transplantation
Surgical Flaps
Veins/surgery
Wound Healing
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:140619
[St] Status:MEDLINE

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[PMID]: 24908734
[Au] Autor:Luo DS; Mo JH; Li M; Zhang ZQ; Lu JJ; Liang ZF; Mi QW; Sun XZ; Deng CH
[Ti] Title:[Suprapubis-assisted umbilical laparoendoscopic mini-dual-site surgery for varicocele: a report of 80 cases].
[So] Source:Zhonghua Nan Ke Xue;20(5):430-4, 2014 May.
[Is] ISSN:1009-3591
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To study the safety, effectiveness and feasibility of suprapubis-assisted umbilical laparoendoscopic mini-dual-site surgery (SAU-LEMDS) in the treatment of varicocele. METHODS: This study included 80 varicocele patients aged 24 - 44 (mean 28.5 +/- 2.6) years, 25 cases of grade I, 45 cases of grade II and 10 cases of grade III, 58 cases in the left side, 6 in the right and 16 in both sides, and all with asthenospermia. The patients were treated by SAU-LEMDS under subarachnoid anesthesia combined with general anesthesia in a supine position with a head-down-feet-up slope of 15 degrees. Two 5 mm trocars were inserted bilaterally at the umbilical edge, one with a 5 mm 30 degrees laparoscope placed in it, and another into the abdominal cavity below the pubic hairline with a 5 mm laparoendoscopic clipper placed in it. The operation procedure was similar to that of standard laparoscopic ligation of spermatic veins, with reservation of the spermatic artery and double-ligation of spermatic veins. And the procedure was repeated for the contralateral lesion in the bilateral cases. Postoperative follow-up was conducted for the incidences of orchiatrophy and testicular hydrocele and changes of seminal parameters. RESULTS: All the operations were successful, with the mean operation time of (10 +/- 5.0) min (range 8 to 25 min) for the unilateral cases and (18 +/- 6.5) min (range 15 to 30 min) for the bilateral cases, the mean blood loss of (1.5 +/- 0.5) ml (range 1 to 2 ml), and the mean postoperative hospital stay of (2 +/- 0.5) d (range 1.5 to 3 d). The patients were followed up for 6 -24 (12 +/- 2.5) months, which showed significant improvement in sperm motility as compared with the baseline ([28.53 +/- 5.21] vs [19.62 +/- 3.56]%, P < 0.05), with 28 cases (35.0%) restored to normal. Recurrence was found in 4 cases (5.0%). Testicular hydrocele occurred in 7 cases (8.75%), but orchiatrophy in none. The scars in the umbilicus and suprapubis were invisible because of the wrinkles and pubic hair. CONCLUSION: SAU-LEMDS is safe, effective and feasible for the treatment of varicocele. It is superior to umbilical laparoendoscopic single-site surgery (U-LESS) for its less invasiveness, simpler operation, and better cosmetic appearance.
[Mh] MeSH terms primary: Laparoscopy/methods
Spermatic Cord/blood supply
Varicocele/surgery
[Mh] MeSH terms secundary: Adult
Asthenozoospermia
Humans
Laparoscopy/adverse effects
Length of Stay
Ligation/methods
Male
Operative Time
Postoperative Period
Recurrence
Testicular Hydrocele/etiology
Treatment Outcome
Umbilicus
Veins
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:140609
[St] Status:MEDLINE

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[PMID]: 24296299
[Au] Autor:Iantorno M; Weiss RG
[Ad] Address:Critical Care Medicine Department, National Institutes of Health, 10 Center Drive, Room 2C145, Bethesda, MD, USA; Department of Medicine, Cardiology Division, The Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21205 USA.
[Ti] Title:Using advanced noninvasive imaging techniques to probe the links between regional coronary artery endothelial dysfunction and atherosclerosis.
[So] Source:Trends Cardiovasc Med;24(4):149-56, 2014 May.
[Is] ISSN:1873-2615
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Cardiovascular disease remains the number one cause of death in the US annually. The development in recent years of imaging strategies that can identify coronary endothelial dysfunction noninvasively provides new information about the early presence and local spatial heterogeneity of endothelial function in patients with, and those at risk for, coronary artery disease. In this article, we will briefly review the mechanisms relating endothelial function and atherosclerosis, contemporary imaging strategies now able to quantify coronary endothelial function noninvasively, and recent insights on human coronary endothelial function.
[Mh] MeSH terms primary: Coronary Artery Disease/diagnosis
Coronary Vessels/physiopathology
Diagnostic Imaging/methods
Endothelium, Vascular/physiopathology
[Mh] MeSH terms secundary: Animals
Coronary Artery Disease/metabolism
Coronary Artery Disease/physiopathology
Coronary Vessels/metabolism
Endothelium, Vascular/metabolism
Humans
Magnetic Resonance Angiography
Multidetector Computed Tomography
Positron-Emission Tomography
Predictive Value of Tests
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1412
[Cu] Class update date: 150515
[Lr] Last revision date:150515
[Js] Journal subset:IM
[Da] Date of entry for processing:140428
[St] Status:MEDLINE

  9 / 159878 MEDLINE  
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[PMID]: 24577771
[Au] Autor:Chen R; Wang H; Wang M; Guan W
[Ad] Address:Department of General Surgery, Gulou Hospital, Nanjing University School of Medicine, Nanjing 210009, China. guan-wx@163.com.
[Ti] Title:[Analysis of risk factors associated with metastasis of lymph node along superior mesenteric vein in patients with gastric cancer].
[So] Source:Zhonghua Wei Chang Wai Ke Za Zhi;17(2):155-7, 2014 Feb.
[Is] ISSN:1671-0274
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To investigate the risk factors associated with metastasis of lymph node along superior mesenteric vein (No.14v) in gastric cancer. METHODS: Clinicopathological data of 70 gastric cancer patients undergoing gastrectomy with No.14v dissection between September 2010 and October 2011 in the Gulou Hospital, Nanjing University School of Medicine were analyzed retrospectively. Associated factors of No.14v lymph nodes metastasis were investigated. RESULTS: Of 70 cases, positive No.14v lymph node metastasis was found in 8 cases (11.4%). Univariate analysis showed that the No.14v metastasis was associated with tumor location (P=0.019), tumor size (P=0.004), depth of invasion (P=0.001), TNM staging (P=0.006), and other lymph node group metastasis (all P<0.05), and was not associated with age, gender, Borrmann classification, Lauren classification or histological type (all P>0.05). Multivariate analysis revealed that lntra-pyloric lymph nodes (No.6) metastasis was an independent risk factor of No.14v metastasis (P<0.05). The predictive accuracy was 94.3% (66/70) and false-negative rate was 1.7% (1/60) for No.6 lymph node metastasis. CONCLUSION: No.6 lymph node metastasis status can predict the metastasis of No.14v more accurately.
[Mh] MeSH terms primary: Mesenteric Veins/pathology
Stomach Neoplasms/pathology
[Mh] MeSH terms secundary: Gastrectomy
Humans
Lymph Node Excision
Lymph Nodes
Lymphatic Metastasis
Neoplasm Staging
Retrospective Studies
Risk Factors
Stomach Neoplasms/surgery
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:140228
[St] Status:MEDLINE

  10 / 159878 MEDLINE  
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[PMID]: 24103172
[Au] Autor:Liu J; Zhang B; Li DZ; Ni S; An CM; Xu ZG; Liu SY
[Ad] Address:Department of Head and Neck Surgery, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China (Email:jieliu04@gmail.com).
[Ti] Title:[Nearby perforator flaps as alternative choices for anterolateral thigh flap when lacking useful perforator].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;48(6):486-9, 2013 Jun.
[Is] ISSN:1673-0860
[Cp] Country of publication:China
[La] Language:chi
[Ab] Abstract:OBJECTIVE: To explore the proposal using nearby perforator flaps as alternative reconstructive choices for anterolateral thigh (ALT) flap when lacking useful perforator. METHODS: From August 2010 to August 2012, 8 cases with head and neck cancer were found lacking reliable perforator during ALT flap elevation, a tensor fascia latae (TFL) flap or an anteromedial thigh (AMT) flap was used to complete the reconstruction. RESULTS: All 8 alternative flaps were successfully harvested, other donor sites were not needed. Flap harvest time was 50-85 min. Of 5 TFL flaps, pedicle lengths were 6-10 cm, and the diameters of the arteries and veins were 2.5-3.0 mm and 2.5-3.5 mm respectively. Of 3 AMT flaps, pedicle lengths were 10-15 cm, the rectus femoris branch was used as pedicle in 1 flap, with artery and vein more than 1.0 mm in diameter, and the descending branch of the lateral circumflex femoral artery was used as pedicle in other 2 flaps, the diameters of the arteries were 3.5 and 3.0 mm respectively, the diameters of the veins were 3.5 mm. The donor sites were directly closed in 7 cases and skin graft was performed in another case. All the flaps were alive and no complication was found in the donor sites. CONCLUSION: TFL or AMT flap is an good alternative to ALT flap lacking useful perforator.
[Mh] MeSH terms primary: Perforator Flap
Reconstructive Surgical Procedures/methods
Surgical Flaps
[Mh] MeSH terms secundary: Arteries
Head and Neck Neoplasms/surgery
Humans
Skin Transplantation
Thigh/surgery
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1505
[Js] Journal subset:IM
[Da] Date of entry for processing:131009
[St] Status:MEDLINE


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