Database : MEDLINE
Search on : air [Words]
References found : 271715 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 27172 go to page                         

  1 / 271715 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 24736103
[Au] Autor:Torrey CM; Moon KA; Williams DA; Green T; Cohen JE; Navas-Acien A; Breysse PN
[Ad] Address:Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA....
[Ti] Title:Waterpipe cafes in Baltimore, Maryland: Carbon monoxide, particulate matter, and nicotine exposure.
[So] Source:J Expo Sci Environ Epidemiol;25(4):405-10, 2015 Jul.
[Is] ISSN:1559-064X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Waterpipe smoking has been growing in popularity in the United States and worldwide. Most tobacco control regulations remain limited to cigarettes. Few studies have investigated waterpipe tobacco smoke exposures in a real world setting. We measured carbon monoxide (CO), particulate matter (PM)2.5, and airborne nicotine concentrations in seven waterpipe cafes in the greater Baltimore area. Area air samples were collected between two and five hours, with an average sampling duration of three hours. Waterpipe smoking behaviors were observed at each venue. Indoor air samplers for CO, PM2.5, and airborne nicotine were placed in the main seating area 1-2 m above the floor. Indoor airborne concentrations of PM2.5 and CO were markedly elevated in waterpipe cafes and exceeded concentrations that were observed in cigarette smoking bars. Air nicotine concentrations, although not as high as in venues that allow cigarette smoking, were markedly higher than in smoke-free bars and restaurants. Concentrations of PM approached occupational exposure limits and CO exceeded occupational exposure guidelines suggesting that worker protection measures need to be considered. This study adds to the literature indicating that both employees and patrons of waterpipe venues are at increased risk from complex exposures to secondhand waterpipe smoke.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Cu] Class update date: 150620
[Lr] Last revision date:150620
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1038/jes.2014.19

  2 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text

[PMID]: 26085952
[Au] Autor:Dubrovin EV; Presnova GV; Rubtsova MY; Egorov AM; Grigorenko VG; Yaminsky IV
[Ad] Address:Department of Physics, Lomonosov Moscow State University, Leninskie gory, 1/2, 119991, Moscow, Russia....
[Ti] Title:The Use of Atomic Force Microscopy for 3D Analysis of Nucleic Acid Hybridization on Microarrays.
[So] Source:Acta Naturae;7(2):108-14, 2015 Apr-Jun.
[Is] ISSN:2075-8251
[Cp] Country of publication:Russia (Federation)
[La] Language:eng
[Ab] Abstract:Oligonucleotide microarrays are considered today to be one of the most efficient methods of gene diagnostics. The capability of atomic force microscopy (AFM) to characterize the three-dimensional morphology of single molecules on a surface allows one to use it as an effective tool for the 3D analysis of a microarray for the detection of nucleic acids. The high resolution of AFM offers ways to decrease the detection threshold of target DNA and increase the signal-to-noise ratio. In this work, we suggest an approach to the evaluation of the results of hybridization of gold nanoparticle-labeled nucleic acids on silicon microarrays based on an AFM analysis of the surface both in air and in liquid which takes into account of their three-dimensional structure. We suggest a quantitative measure of the hybridization results which is based on the fraction of the surface area occupied by the nanoparticles.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Cu] Class update date: 150620
[Lr] Last revision date:150620
[Da] Date of entry for processing:150618
[St] Status:PubMed-not-MEDLINE

  3 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 25939513
[Au] Autor:Matsuo J; Nakamura S; Takeda S; Ishida K; Yamazaki T; Yoshida M; Chiba H; Hui SP; Yamaguchi H
[Ad] Address:Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan....
[Ti] Title:Synergistic Costimulatory Effect of Chlamydia pneumoniae with Carbon Nanoparticles on NLRP3 Inflammasome-Mediated Interleukin-1ß Secretion in Macrophages.
[So] Source:Infect Immun;83(7):2917-25, 2015 Jul.
[Is] ISSN:1098-5522
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The obligate intracellular bacterium Chlamydia pneumoniae is not only a causative agent of community-acquired pneumonia but is also associated with a more serious chronic disease, asthma, which might be exacerbated by air pollution containing carbon nanoparticles. Although a detailed mechanism of exacerbation remains unknown, the proinflammatory cytokine interleukin-1ß (IL-1ß) is a critical player in the pathogenesis of asthma. C. pneumoniae induces IL-1ß in macrophages via NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activation and Toll-like receptor 2/4 (TLR2/4) stimulation. Carbon nanoparticles, such as carbon nanotubes (CNTs), can also evoke the NLRP3 inflammasome to trigger IL-1ß secretion from lipopolysaccharide-primed macrophages. This study assessed whether costimulation of C. pneumoniae with CNTs synergistically enhanced IL-1ß secretion from macrophages, and determined the molecular mechanism involved. Enhanced IL-1ß secretion from C. pneumoniae-infected macrophages by CNTs was dose and time dependent. Transmission electron microscopy revealed that C. pneumoniae and CNTs were engulfed concurrently by macrophages. Inhibitors of actin polymerization or caspase-1, a component of the inflammasome, significantly blocked IL-1ß secretion. Gene silencing using small interfering RNA (siRNA) targeting the NLRP3 gene also abolished IL-1ß secretion. Other inhibitors (K(+) efflux inhibitor, cathepsin B inhibitor, and reactive oxygen species-generating inhibitor) also blocked IL-1ß secretion. Taken together, these findings demonstrated that CNTs synergistically enhanced IL-1ß secretion from C. pneumoniae-infected macrophages via the NLRP3 inflammasome and caspase-1 activation, providing novel insight into our understanding of how C. pneumoniae infection can exacerbate asthma.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Cu] Class update date: 150620
[Lr] Last revision date:150620
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1128/IAI.02968-14

  4 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 26060272
[Au] Autor:Chen Y; Gozzi K; Yan F; Chai Y
[Ad] Address:Institute of Biotechnology, Zhejiang University, Hangzhou, China.
[Ti] Title:Acetic Acid Acts as a Volatile Signal To Stimulate Bacterial Biofilm Formation.
[So] Source:MBio;6(3), 2015.
[Is] ISSN:2150-7511
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:UNLABELLED: Volatiles are small air-transmittable chemicals with diverse biological activities. In this study, we showed that volatiles produced by the bacterium Bacillus subtilis had a profound effect on biofilm formation of neighboring B. subtilis cells that grew in proximity but were physically separated. We further demonstrated that one such volatile, acetic acid, is particularly potent in stimulating biofilm formation. Multiple lines of genetic evidence based on B. subtilis mutants that are defective in either acetic acid production or transportation suggest that B. subtilis uses acetic acid as a metabolic signal to coordinate the timing of biofilm formation. Lastly, we investigated how B. subtilis cells sense and respond to acetic acid in regulating biofilm formation. We showed the possible involvement of three sets of genes (ywbHG, ysbAB, and yxaKC), all encoding putative holin-antiholin-like proteins, in cells responding to acetic acid and stimulating biofilm formation. All three sets of genes were induced by acetate. A mutant with a triple mutation of those genes showed a severe delay in biofilm formation, whereas a strain overexpressing ywbHG showed early and robust biofilm formation. Results of our studies suggest that B. subtilis and possibly other bacteria use acetic acid as a metabolic signal to regulate biofilm formation as well as a quorum-sensing-like airborne signal to coordinate the timing of biofilm formation by physically separated cells in the community. IMPORTANCE: Volatiles are small, air-transmittable molecules produced by all kingdoms of organisms including bacteria. Volatiles possess diverse biological activities and play important roles in bacteria-bacteria and bacteria-host interactions. Although volatiles can be used as a novel and important way of cell-cell communication due to their air-transmittable nature, little is known about how the volatile-mediated signaling mechanism works. In this study, we demonstrate that the bacterium Bacillus subtilis uses one such volatile, acetic acid, as a quorum-sensing-like signal to coordinate the timing of the formation of structurally complex cell communities, also known as biofilms. We further characterized the molecular mechanisms of how B. subtilis responds to acetic acid in stimulating biofilm formation. Our study also suggests that acetic acid may be used as a volatile signal for cross-species communication.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Cu] Class update date: 150620
[Lr] Last revision date:150620
[Js] Journal subset:IM
[St] Status:In-Data-Review

  5 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 25808165
[Au] Autor:Honda A; Tsuji K; Matsuda Y; Hayashi T; Fukushima W; Sawahara T; Kudo H; Murayama R; Takano H
[Ad] Address:Department of Environmental Engineering, Environmental Health Division, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto, Japan akko@health.env.kyoto-u.ac.jp....
[Ti] Title:Effects of air pollution-related heavy metals on the viability and inflammatory responses of human airway epithelial cells.
[So] Source:Int J Toxicol;34(2):195-203, 2015 Mar-Apr.
[Is] ISSN:1092-874X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Various metals produced from human activity are ubiquitously detected in ambient air. The metals may lead to induction and/or exacerbation of respiratory diseases, but the significant metals and factors contributing to such diseases have not been identified. To compare the effects of each metal and different oxidation states of metals on human airway, we examined the viability and production of interleukin (IL)-6 and IL-8 using BEAS-2B cell line, derived from human airway epithelial cells. Airway epithelial cells were exposed to Mn(2+), V(4+), V(5+), Cr(3+), Cr(6+), Zn(2+), Ni(2+), and Pb(2+) at a concentration of 0.5, 5, 50, or 500 µmol/L for 24 hours. Mn and V decreased the cell viability in a concentration-dependent manner, and V(5+) tended to have a greater effect than V(4+). The Cr decreased the cell viability, and (Cr(+6)) at concentrations of 50 and 500 µmol/L was more toxic than (Cr(+3)). Zn at a concentration of 500 µmol/L greatly decreased the cell viability, whereas Ni at the same concentration increased it. Pb produced fewer changes. Mn and Ni at a concentration of 500 µmol/L induced the significant production of IL-6 and IL-8. However, most of the metals including (V(+4), V(+5)), (Cr(+3), Cr(+6)), Zn, and Pb inhibited the production of both IL-6 and IL-8. The present results indicate that various heavy metals have different effects on toxicity and the proinflammatory responses of airway epithelial cells, and those influences also depend on the oxidation states of the metals.
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Entry month:1504
[Js] Journal subset:IM
[St] Status:In-Process
[do] DOI:10.1177/1091581815575757

  6 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
PubMed Central Full text
Full text

[PMID]: 24796880
[Au] Autor:Benderro GF; LaManna JC
[Ad] Address:Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, USA.
[Ti] Title:HIF-1α/COX-2 expression and mouse brain capillary remodeling during prolonged moderate hypoxia and subsequent re-oxygenation.
[So] Source:Brain Res;1569:41-7, 2014 Jun 20.
[Is] ISSN:1872-6240
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Dynamic microvascular remodeling maintains an optimal continuous supply of oxygen and nutrients to the brain to account for prolonged environmental variations. The objective of this study was to determine the relative time course of capillary regression during re-oxygenation after exposure to prolonged moderate hypoxia and expression of the primary signaling factors involved in the process. Four-month old male C57BL/6 mice were housed and maintained in a hypobaric chamber at 290 Torr (0.4 atm) for 21 days and allowed to recover at normoxia (room air) for up to 21 days. The mice were either decapitated or perfused in-situ and brain samples collected were either homogenized for Western blot analysis or fixed and embedded in paraffin for immunohistochemistry. Hypoxia inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and erythropoietin (EPO) expression were increased during hypoxic exposure and diminished during subsequent re-oxygenation. However, cyclooxygenase-2 (COX-2) and angiopoietin-2 (Ang-2) were both elevated during hypoxia as well as subsequent re-oxygenation. Significantly increased capillary density at the end of the 3rd week of hypoxia regressed back toward normoxic baseline as the duration of re-oxygenation continued. In conclusion, elevated COX-2 and Ang-2 expression during hypoxia where angiogenesis occurs and re-oxygenation, when micro-vessels regress, identifies these proteins as vascular remodeling molecules crucial for angioplasticity.
[Mh] MeSH terms primary: Brain/blood supply
Brain/metabolism
Cyclooxygenase 2/metabolism
Hypoxia, Brain/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
Vascular Remodeling
[Mh] MeSH terms secundary: Angiopoietin-2/metabolism
Animals
Brain/enzymology
Erythropoietin/metabolism
Hypoxia, Brain/enzymology
Male
Mice
Mice, Inbred C57BL
Oxygen/metabolism
Vascular Endothelial Growth Factor A/metabolism
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Name of substance:0 (Angiopoietin-2); 0 (Hif1a protein, mouse); 0 (Hypoxia-Inducible Factor 1, alpha Subunit); 0 (Vascular Endothelial Growth Factor A); 0 (vascular endothelial growth factor A, mouse); 11096-26-7 (Erythropoietin); EC 1.14.99.- (Ptgs2 protein, mouse); EC 1.14.99.1 (Cyclooxygenase 2); S88TT14065 (Oxygen)
[Em] Entry month:1412
[Cu] Class update date: 150620
[Lr] Last revision date:150620
[Js] Journal subset:IM
[Da] Date of entry for processing:140604
[St] Status:MEDLINE

  7 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 26022408
[Au] Autor:Qin XD; Qian Z; Vaughn MG; Trevathan E; Emo B; Paul G; Ren WH; Hao YT; Dong GH
[Ad] Address:Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Environmental and Occupational Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, PR China....
[Ti] Title:Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study.
[So] Source:Sci Total Environ;529:243-8, 2015 Oct 1.
[Is] ISSN:1879-1026
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:BACKGROUND: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. METHODS: We studied 24,845 Chinese adults, aged 18 to 74years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25-29.9 and ≥30kg/m(2), respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006-2008) average concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), and ozone (O3) were measured by fixed monitoring stations. All the participants lived within 1km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. RESULTS: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15-1.47 for stroke, 1.33-1.59 for CVDs), less strong in overweight subjects (OR 1.22-1.35 for stroke, 1.07-1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98-1.01 for stroke, 0.93-1.15 for CVDs). When stratified by gender, these interactions were significant only in women. CONCLUSIONS: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Js] Journal subset:IM
[St] Status:In-Data-Review

  8 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 26022404
[Au] Autor:Oiamo TH; Johnson M; Tang K; Luginaah IN
[Ad] Address:Department of Geography, Social Science Centre, The University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 5C2, Canada. Electronic address: thoiamo@uwo.ca....
[Ti] Title:Assessing traffic and industrial contributions to ambient nitrogen dioxide and volatile organic compounds in a low pollution urban environment.
[So] Source:Sci Total Environ;529:149-57, 2015 Oct 1.
[Is] ISSN:1879-1026
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Land use regression (LUR) modeling is an effective method for estimating fine-scale distributions of ambient air pollutants. The objectives of this study are to advance the methodology for use in urban environments with relatively low levels of industrial activity and provide exposure assessments for research on health effects of air pollution. Intraurban distributions of nitrogen dioxide (NO2) and the volatile organic compounds (VOCs) benzene, toluene and m- and p-xylene were characterized based on spatial monitoring and LUR modeling in Ottawa, Ontario, Canada. Passive samplers were deployed at 50 locations throughout Ottawa for two consecutive weeks in October 2008 and May 2009. Land use variables representing point, area and line sources were tested as predictors of pooled pollutant distributions. LUR models explained 96% of the spatial variability in NO2 and 75-79% of the variability in the VOC species. Proximity to highways, green space, industrial and residential land uses were significant in the final models. More notably, proximity to industrial point sources and road network intersections were significant predictors for all pollutants. The strong contribution of industrial point sources to VOC distributions in Ottawa suggests that facility emission data should be considered whenever possible. The study also suggests that proximity to road network intersections may be an effective proxy in areas where reliable traffic data are not available.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Js] Journal subset:IM
[St] Status:In-Data-Review

  9 / 271715 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 26005750
[Au] Autor:Du L; Turner J
[Ad] Address:Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, Campus Box 1180, One Brookings Drive, St. Louis, MO 63130, USA.
[Ti] Title:Using PM2.5 lanthanoid elements and nonparametric wind regression to track petroleum refinery FCC emissions.
[So] Source:Sci Total Environ;529:65-71, 2015 Oct 1.
[Is] ISSN:1879-1026
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:A long term air quality study is being conducted in Roxana, Illinois, USA, at the fenceline of a petroleum refinery. Measurements include 1-in-6day 24-hour integrated ambient fine particulate matter (PM2.5) speciation following the Chemical Speciation Network (CSN) sampling and analysis protocols. Lanthanoid elements, some of which are tracers of fluidized-bed catalytic cracker (FCC) emissions, are also measured by inductively coupled plasma-mass spectrometry (ICP-MS) after extraction from PM2.5 using hot block-assisted acid digestion. Lanthanoid recoveries of 80-90% were obtained for two ambient particulate matter standard reference materials (NIST SRM 1648a and 2783). Ambient PM2.5 La patterns could be explained by a two-source model representing resuspended soil and FCC emissions with enhanced La/Ce ratios when impacted by the refinery. Nonparametric wind regression demonstrates that when the monitoring station was upwind of the refinery the mean La/Ce ratio is consistent with soil and when the monitoring station is downwind of the refinery the mean ratio is more than four times higher for bearings that corresponds to maximum impacts. Source apportionment modeling using EPA UNMIX and EPA PMF could not reliably apportion PM2.5 mass to the FCC emissions. However, the weight of evidence is that such contributions are small with no large episodes observed for the 164 samples analyzed. This study demonstrates the applicability of a hot block-assisted digestion protocol for the extraction of lanthanoid elements as well as insights obtained from long-term monitoring data including wind direction-based analyses.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Js] Journal subset:IM
[St] Status:In-Data-Review

  10 / 271715 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 25948708
[Au] Autor:Bormashenko E; Shapira Y; Grynyov R; Whyman G; Bormashenko Y; Drori E
[Ad] Address:Ariel University, Physics Faculty, POB 3, 40700, Ariel, Israel Ariel University, Chemical Engineering and Biotechnology Faculty, POB 3, 40700, Ariel, Israel Edward@ariel.ac.il....
[Ti] Title:Interaction of cold radiofrequency plasma with seeds of beans (Phaseolus vulgaris).
[So] Source:J Exp Bot;66(13):4013-21, 2015 Jul.
[Is] ISSN:1460-2431
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The impact of cold radiofrequency air plasma on the wetting properties and water imbibition of beans (Phaseolus vulgaris) was studied. The influence of plasma on wetting of a cotyledon and seed coat (testa) was elucidated. It was established that cold plasma treatment leads to hydrophilization of the cotyledon and tissues constituting the testa when they are separately exposed to plasma. By contrast, when the entire bean is exposed to plasma treatment, only the external surface of the bean is hydrophilized by the cold plasma. Water imbibition by plasma-treated beans was studied. Plasma treatment markedly accelerates the water absorption. The crucial role of a micropyle in the process of water imbibition was established. It was established that the final percentage of germination was almost the same in the cases of plasma-treated, untreated, and vacuum-pumped samples. However, the speed of germination was markedly higher for the plasma-treated samples. The influence of the vacuum pumping involved in the cold plasma treatment on the germination was also clarified.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1506
[Js] Journal subset:IM
[St] Status:In-Data-Review
[do] DOI:10.1093/jxb/erv206


page 1 of 27172 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information