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[PMID]: 29099343
[Au] Autor:Sedlacik J; Kjørstad Å; Nagy Z; Buhk JH; Behem CR; Trepte CJ; Fiehler J; Temme F
[Ad] Address:1 Department of Neuroradiology, University Medical Center Hamburg-Eppendorf , Hamburg, Germany .
[Ti] Title:Feasibility Study of a Novel High-Flow Cold Air Cooling Protocol of the Porcine Brain Using MRI Temperature Mapping.
[So] Source:Ther Hypothermia Temp Manag;, 2017 Nov 03.
[Is] ISSN:2153-7933
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Early, prehospital cooling seeks to reduce and control the body temperature as early as possible to protect the brain and improve patient outcome in cardiac arrest, stroke, and traumatic brain injury. In this study, we investigate the feasibility of localized cooling of the porcine brain by using a novel high-flow cold air protocol, which utilizes the close proximity between the nasal cavity and the brain. Five adult pigs were anesthetized and temperature change was mapped before, during, and after cooling by using the proton resonance frequency method on a 3 T Siemens Magnetom Skyra system. Cooling was performed by inserting a tube blowing high-flow (250 L/min) cold air (-10°C) through the nasal cavity for 5-20 minutes. The brain temperature change was measured by using an MRI phase mapping technique utilizing the temperature-dependent proton resonance frequency change. MRI maps showed significant temperature reduction of the porcine brain. On average, a mean whole-brain cooling effect of -0.33°C ± 0.30°C was found after 5 minutes of cooling. The anterior part of the brain was directly exposed to the cold and showed a significantly larger temperature drop (-0.83°C ± 0.51°C) than the posterior part (-0.03°C ± 0.21°C). However, a large variability of the temperature drop was observed between the animals. This variability may be caused by not well-controlled factors confounding the MRI temperature mapping, for example, subject movement, or cooling effectiveness, for example, core temperature or nasal patency. The results indicate that the proposed high-flow cold air protocol allows for localized cooling of the frontal porcine brain, which may be clinically relevant for traumatic injuries of the frontal brain where systemic cooling is unfavorable.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1089/ther.2017.0031

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[PMID]: 29099232
[Au] Autor:Alper CM; Rath TJ; Teixeira MS; Swarts JD
[Ad] Address:1 Department of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
[Ti] Title:A Novel Imaging Method for the Cartilaginous Eustachian Tube Lumen: Computerized Tomography During the Forced Response Test.
[So] Source:Ann Otol Rhinol Laryngol;:3489417740363, 2017 Nov 01.
[Is] ISSN:1943-572X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVES: In vivo imaging of the open cartilaginous Eustachian tube (ET) lumen by computed tomography (CT) scan during ET function (ETF) testing to establish new methodology. METHODS: Five adults underwent unilateral ETF testing of an ear with a nonintact tympanic membrane using the forced response test (FRT) to measure the opening pressure (PO), steady state pressure (PS), and flow conductance (CS). Then at baseline and during the PS phase of the FRT, a temporal-bone CT scan with continuous 0.625 mm thickness was obtained. Multiplanar oblique reformats along the axis of the ET were created, and point value and region of interest (ROI) Hounsfield unit measurements were recorded from the location of the ET lumen. RESULTS: At the FRT flow rate of 11 ml/min, the average PO, PS, and CS were 370.5 daPa, 119.6 daPa, and 0.16 ml/min/daPa, respectively. For flow rates of 23 and 46 ml/min, these values were 236.2, 204.2, 0.12 and 385.5, 321.1, 0.18, respectively. Although areas with lower attenuation were suggestive of air density, a distinct air-filled cartilaginous ET lumen could not be confirmed. CONCLUSIONS: While the current imaging parameters failed to resolve the air-soft tissue interface throughout the open cartilaginous ET, further advances in imaging may obviate this limitation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1177/0003489417740363

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[PMID]: 29098963
[Au] Autor:Tian X; Ahmed W; Delatolla R
[Ad] Address:a Department of Civil Engineering , University of Ottawa , Ottawa , ON , Canada 161 Louis Pasteur, K1N 6N5.
[Ti] Title:Nitrifying bio-cord reactor: performance optimization and effects of substratum and air scouring.
[So] Source:Environ Technol;:1-27, 2017 Nov 03.
[Is] ISSN:0959-3330
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Ammonia removal kinetics and solids production performance of the bio-cord technology are studied in this research. Three nitrifying reactors housing different bio-cord substratum were operated at five different ammonia loading rates. All of the bio-cord substrata demonstrated stable and high ammonia nitrogen removal efficiencies of 96.8 ± 0.9, 97.0 ± 0.6and 92.0 ± 0.4% at loading rates of 0.8, 1.6 and 1.8 g NH -N/m ·d, respectively. At these same loading rates, the bio-cord reactors housing the three substrata also showed low solids production rates of 0.19 ± 0.03, 0.23 ± 0.02, 0.25 ± 0.03 g TSS/d. A reduction of system stability, identified via fluctuating ammonia removal rates was however observed for all substrata at loading rates of 2.1 and 2.4 g NH -N/m ·d. Further, the solids production rates at these higher loading conditions were also observed to fluctuate for all substrata, likely indicating intermediate sloughing events. The effects of enhancing the air scouring of the bio-cord on the ammonia removal rate was shown to be dependent upon the substratum, while enhanced air scouring of the bio-cord was shown to stabilize the production of solids for all substrata. This study represents the first performance and optimization study of the bio-cord technology for tertiary, low carbon nitrification and shows that air scouring of the substratum reduces sloughing events at elevated loading rates and that the bio-cord technology operated with various substratum achieves stable nitrification kinetics above conventional rates of 1 g NH -N/ m ·d to values of 1.8 g NH -N/ m ·d.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1080/09593330.2017.1397760

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[PMID]: 29098952
[Au] Autor:Nassima T; Mahmoud A; Annabelle C; Abdeltif A; Amina T
[Ad] Address:a Laboratoire de Biomatériaux et Phénomènes de Transport, Faculté des Sciences et de la Technologie , Université Yahia Fares de Médéa , Pole Universitaire, RN1, Médéa 26000, Algérie.
[Ti] Title:A combination of absorption and enzymatic biodegradation: phenol elimination from aqueous and organic phase.
[So] Source:Environ Technol;:1-23, 2017 Nov 03.
[Is] ISSN:0959-3330
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Peroxidase from Brassica rapa (BRP) was immobilized as cross-linked enzyme aggregates (CLEAs) and used to treat air containing phenol as a model molecule of volatile organic compounds (VOCs). Prior to enzymatic treatment, phenol was absorbed into aqueous or organic phase (silicone oil, Rhodorsil® 47V20) to reach concentrations ranging from 20 to 160mg/L. The process of enzymatic degradation was carried out by introducing a desired weighing of BRP-CLEAs into preparations and reaction was started by injecting H O solution to medium. Optimization of the reaction conditions in the organic solvent revealed an optimal contact time of 60 min, 60 mg/L initial phenol concentration and 3 mM H O , leading to a maximum phenol removal yield of 70% for 3.4 UI/mL of BRP-CLEAs. These results were compared to those obtained in aqueous medium that showed 90% of VOC degradation yield after 40 min in the following conditions, 90 mg/L initial phenol amount, 2 mM of H O and an enzyme activity of 2.5 UI/mL. Parameters of the Michaelis-Menten model, K and V , were also determined for the reaction of phenol degradation by BRP-CLEAs in both silicone oil and water. Phenol removal by Brassica rapa cross-linked enzyme in silicone oil succeeded with 70% of conversion yield. It is promising regarding the transposition of such enzymatic process to hydrophobic VOCs.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1080/09593330.2017.1400110

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[PMID]: 29098945
[Au] Autor:Tabernacka A; Zborowska E; Pogoda K; Zoladek M
[Ad] Address:a Biology Division, Faculty of Building Services, Hydro and Environmental Engineering , Warsaw University of Technology.
[Ti] Title:Removal of tetrachloroethene from polluted air by activated sludge.
[So] Source:Environ Technol;:1-38, 2017 Nov 03.
[Is] ISSN:0959-3330
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:One-step technological system containing activated sludge fed with synthetic domestic wastewater was applied to treat waste air polluted with tetrachloroethene. In the first stage of the experiment, air passed through bioscrubber, in the second and third stage - through the bioreactor containing activated sludge and bacteria immobilised in oak chips. These bacteria are active in tetrachloroethene biodegradation. Process efficiency in the final stage of experiment was high, the elimination capacity was 0.23 g•m •h with the tetrachloroethene mass loading rate of 0.58 g•m •h . It has been shown that in the activated sludge bioreactor bacteria adapted to tetrachloroethene biodegradation, and that the wood chips protected microorganisms from the toxic effects of pollution. The dominant strains of bacteria immobilised in wood chips have been identified. Most of them were Gram negative rods - Pseudomonas aeruginosa, Pseudomonas putida, Ralstonia picketii and Ochrobactrum anthropii. Only one strain was Gram-positive, of cylindrical shape. The results of the study indicate the potential of immobilised bacteria capable of degrading chlorinated aliphatic hydrocarbons for the air and wastewater treatment. Advantageous is a low cost of the treatment process.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1080/09593330.2017.1397759

  6 / 312247 MEDLINE  
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[PMID]: 29098940
[Au] Autor:Dai Z; Lu X; Jing Z
[Ad] Address:a School of Energy and Environment , Southeast University , Nanjing 210096 , China.
[Ti] Title:Nitrogen and phosphorus removal processes under different aeration strength in principal-type tank of Alternate Multiple Tanks system and process control.
[So] Source:Environ Technol;:1-26, 2017 Nov 03.
[Is] ISSN:0959-3330
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The Alternate multiple tanks (AMT) system was originated by Southeast University to meet pressing requirements of new highly-compact sewage treatment with cost-effective balance and automated management. DO and ORP as economic monitoring indicators are closely linked to nutrients variations and controlling strategy. Thus this paper was to investigate the N and P periodic variations and removal mechanisms under different aeration strengths in scope of principal-type tank in AMT, and the relationship between nutrients and DO, ORP. Results showed that N and P removal could reach an optimal balance when the air-water ratio (Rs) was 30 where the aeration strength was 540L/h under inflow of 18L/h. And under the optimized conditions, the TP, TN, ammonia and nitrate remained 0.4 mg/L (88.4% of removal efficiency), 5.0 mg/L (84.7%), 0.5 mg/L (98.4%) and 4.0 mg/L, respectively during the discharge stage. Restrained aeration reduced the efficiency of P release and uptake and retarded the oxidizing rate of ammonia and nitrification. While excessive aeration broke the balance of P release and uptake, prevented denitrification due to its high residual DO, and had no effect on nitrifying in comparison to moderate aeration. Inadequate aeration caused DO values in low level and insensitive to controlling critical points, while redundant aeration was of no extra use compared to moderate aeration. Based on the processes, an enhanced practical real-time response of DO and ORP to nutrients change and control policy was obtained, where characteristic points of TP and nitrogen were sensitive to the systematic manipulation and DO, ORP variations.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1080/09593330.2017.1397761

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[PMID]: 29098799
[Au] Autor:Alderete TL; Song AY; Bastain T; Habre R; Toledo-Corral CM; Salam MT; Lurmann F; Gilliland FD; Breton CV
[Ad] Address:Department of Preventive Medicine, Division of Environmental Health, University of Southern California, Los Angeles, USA.
[Ti] Title:Prenatal traffic-related air pollution exposures, cord blood adipokines and infant weight.
[So] Source:Pediatr Obes;, 2017 Nov 03.
[Is] ISSN:2047-6310
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Studies suggest that prenatal exposure to traffic-related air pollution (TRAP) may contribute to childhood obesity. While exact mechanisms for this association are unknown, circulating adipokines are hypothesized to contribute to early-life weight gain. METHODS: The Maternal and Child Health Study birth cohort included 136 women from the Los Angeles County + University of Southern California Medical Center. This study estimated prenatal residential TRAP exposure and used linear regression analysis to examine associations between adipokines with TRAP exposure and infant weight change (birth to 6 months). RESULTS: A one standard deviation (1-SD: 2 ppb) increase in prenatal non-freeway nitrogen oxides was associated with 33% (P = 0.01) higher leptin and 9% higher high molecular weight adiponectin levels (P = 0.07) in cord blood. Leptin levels were 71% higher in mothers who lived <75 m than those living >300 m from major roadways (P = 0.03). A 1-SD (10 ng mL ) increase in leptin was associated with a significant increase in infant weight change in female infants (0.62 kg, P = 0.02) but not male infants (0.11 kg, P = 0.48). CONCLUSIONS: Higher TRAP exposures were associated with higher cord blood levels of leptin and high molecular weight adiponectin. These adipokines were associated with increased infant weight change in female infants, which may have implications for future obesity risk.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1111/ijpo.12248

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[PMID]: 29098642
[Au] Autor:Koscielniak A; Serafin M; Duda M; Oles T; Zadlo A; Broniec A; Berdeaux O; Gregoire S; Bretillon L; Sarna T; Pawlak A
[Ad] Address:Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
[Ti] Title:Oxidation-Induced Increase In Photoreactivity of Bovine Retinal Lipid Extract.
[So] Source:Cell Biochem Biophys;, 2017 Nov 02.
[Is] ISSN:1559-0283
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The mammalian retina contains a high level of polyunsaturated fatty acids, including docosahexaenoic acid (22:6) (DHA), which are highly susceptible to oxidation. It has been shown that one of the products of DHA oxidation-carboxyethylpyrrole (CEP), generated in situ, causes modifications of retinal proteins and induces inflammation response in the outer retina. These contributing factors may play a role in the development of age-related macular degeneration (AMD). It is also possible that some of the lipid oxidation products are photoreactive, and upon irradiation with blue light may generate reactive oxygen species. Therefore, in this work we analysed oxidation-induced changes in photoreactivity of lipids extracted from bovine neural retinas. Lipid composition of bovine neural retinas closely resembles that of human retinas making the bovine tissue a convenient model for studying the photoreactivity and potential phototoxicity of oxidized human retinal lipids. Lipid composition of bovine neural retinas Folch' extracts (BRex) was determined by gas chromatography (GC) and liquid chromatography coupled to an electrospray ionization source-mass spectrometer (LC-ESI-MS) analysis. Liposomes prepared from BRex, equilibrated with air, were oxidized in the dark at 37 °C for up to 400 h. The photoreactivity of BRex at different stages of oxidation was studied by EPR-oximetry and EPR-spin trapping. Photogeneration of singlet oxygen ( O , Δ ) by BRex was measured using time-resolved detection of the characteristic phosphorescence at 1270 nm. To establish contribution of lipid components to the analysed photoreactivity of Folch' extract of bovine retinas, a mixture of selected synthetic lipids in percent by weight (w/w %) ratio resembling that of the BRex has been also studied. Folch's extraction of bovine neural retinas was very susceptible to oxidation despite the presence of powerful endogenous antioxidants such as α-tocopherol and zeaxanthin. Non-oxidized and oxidized BRex photogenerated singlet oxygen with moderate quantum yield. Blue-light induced generation of superoxide anion by Folch' extract of bovine neural retinas strongly depended on the oxidation time. The observed photoreactivity of the studied extract gradually increased during its in vitro oxidation.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1007/s12013-017-0832-3

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[PMID]: 29098476
[Au] Autor:Alves AGF; de Azevedo Giacomin MF; Braga ALF; Sallum AME; Pereira LAA; Farhat LC; Strufaldi FL; de Faria Coimbra Lichtenfels AJ; de Santana Carvalho T; Nakagawa NK; Silva CA; Farhat SCL
[Ad] Address:Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
[Ti] Title:Influence of air pollution on airway inflammation and disease activity in childhood-systemic lupus erythematosus.
[So] Source:Clin Rheumatol;, 2017 Nov 02.
[Is] ISSN:1434-9949
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:Exposure to fine particles may trigger pulmonary inflammation/systemic inflammation. The objective of this study was to investigate the association between daily individual exposure to air pollutants and airway inflammation and disease activity in childhood-onset systemic lupus erythematosus (cSLE) patients. A longitudinal panel study was carried out in 108 consecutive appointments with cSLE patients without respiratory diseases. Over four consecutive weeks, daily individual measures of nitrogen dioxide (NO ), fine particulate matter (PM ), ambient temperature, and humidity were obtained. This cycle was repeated every 2.5 months along 1 year, and cytokines of exhaled breath condensate-EBC [interleukins (IL) 6, 8, 17 and tumoral necrose factor-α (TNF-α)], fractional exhaled NO (FeNO), and disease activity parameters were collected weekly. Specific generalized estimation equation models were used to assess the impact of these pollutants on the risk of Systemic Lupus Erythematous Disease Activity Index 2000 (SLEDAI-2K) ≥ 8, EBC cytokines, and FeNO, considering the fixed effects for repetitive measurements. The models were adjusted for inflammatory indicators, body mass index, infections, medication, and weather variables. An IQR increase in PM 4-day moving average (18.12 µg/m ) was associated with an increase of 0.05 pg/ml (95% CI 0.01; 0.09, p = 0.03) and 0.04 pg/ml (95% CI 0.02; 0.06, p = 0.01) in IL-17 and TNF-α EBC levels, respectively. Additionally, a short-term effect on FeNO was observed: the PM 3-day moving average was associated with a 0.75 ppb increase (95% CI 0.38; 1.29, p = 0.03) in FeNO. Also, an increase of 1.47 (95% CI 1.10; 1.84) in the risk of SLEDAI-2K ≥ 8 was associated with PM 7-day moving average. Exposure to inhalable fine particles increases airway inflammation/pulmonary and then systemic inflammation in cSLE patients.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1007/s10067-017-3893-1

  10 / 312247 MEDLINE  
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[PMID]: 29098422
[Au] Autor:Park J; Kim S; Kim DH; Cha S; Lee JY
[Ad] Address:Research Institute of Human Ecology, Seoul National University, Seoul, Republic of Korea.
[Ti] Title:Whole-body cold tolerance in older Korean female divers "haenyeo" during cold air exposure: effects of repetitive cold exposure and aging.
[So] Source:Int J Biometeorol;, 2017 Nov 03.
[Is] ISSN:1432-1254
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:This study was conducted to investigate the effects of chronic and repetitive diving in cold sea water on physiological responses to cold in older Korean female divers, Haenyeo, who have been exposed to cold water through breath-hold diving since their teens. Young and older females, who have no experience of swimming in cold sea water, were recruited as control groups: older haenyeos (N = 10, 70 ± 3 years of age), young non-diving females (N = 10, 23 ± 2 years), and older non-diving females (N = 6, 73 ± 4 years). For the test of cold exposure, all subjects were exposed to cold in an air temperature of 12 °C with 45% RH in a sitting position for 60 min. The changes in core temperature showed no significant differences between older haenyeos and the other two groups. The decreases in mean skin temperature were greater for older haenyeos than the other two groups (P < 0.01). Older haenyeos had significantly lower energy expenditure during cold exposure when compared to older non-diving females (P < 0.05). Heart rate was significantly lower in older haenyeos than that of young non-diving females (P < 0.05). Older haenyeos felt cooler at the face with lower face temperature when compared with older non-diving females. The results indicate that older haenyeos respond to cold through reducing heat loss from the skin rather than increasing metabolic rate. These responses are distinctive features from the cold defensive system of young or older non-diving females.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1007/s00484-017-1463-5


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