Database : MEDLINE
Search on : carotenoids [Words]
References found : 22373 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 2238 go to page                         

  1 / 22373 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29367485
[Au] Autor:Umigai N; Murakami K; Shimizu R; Takeda R; Azuma T
[Ad] Address:Riken Vitamin Co., Ltd.
[Ti] Title:Safety Evaluation and Plasma Carotenoid Accumulation in Healthy Adult Subjects after 12 Weeks of Paprika Oleoresin Supplementation.
[So] Source:J Oleo Sci;67(2):225-234, 2018 Feb 01.
[Is] ISSN:1347-3352
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Paprika oleoresin is obtained by solvent extraction from Capsicum annuum L. fruits and contains multiple carotenoids, such as capsanthin, ß-carotene, zeaxanthin, and ß-cryptoxanthin, which are considered protective against various diseases. Herein, we investigated the effect of paprika oleoresin supplementation on plasma carotenoid accumulation and evaluated the safety of the oleoresin. We used a double-blinded, placebo-controlled comparative clinical study design and tested the effects of varying doses in healthy adult subjects. In total, 33 subjects were randomly divided into three groups to take capsules containing 0, 20, or 100 mg of paprika oleoresin daily for 12 consecutive weeks. Plasma carotenoid concentrations were measured at 0, 4, 8, and 12 weeks, and the safety of paprika oleoresin capsules was investigated using analyses of blood biochemistry, hematology, and urine contents. In these experiments, ß-cryptoxanthin and zeaxanthin dose-dependently accumulated in plasma within the dose range of the study over 12 consecutive weeks of paprika oleoresin supplementation. Moreover, ß-cryptoxanthin accumulated to higher levels than the other paprika oleoresin carotenoids. In contrast, capsanthin was not detected in plasma before or during the 12-week treatment period. Finally, no adverse events were associated with intake of paprika oleoresin (20 and 100 mg/day) in safety evaluations. Paprika oleoresin is a suitable source of carotenoids, especially ß-cryptoxanthin.
[Mh] MeSH terms primary: Capsicum/chemistry
Carotenoids/blood
Dietary Supplements
Plant Extracts/administration & dosage
Plant Extracts/isolation & purification
[Mh] MeSH terms secundary: Beta-Cryptoxanthin/blood
Dietary Supplements/adverse effects
Dose-Response Relationship, Drug
Double-Blind Method
Plant Extracts/adverse effects
Random Allocation
Safety
Solvents
Time Factors
Zeaxanthins/blood
[Pt] Publication type:CLINICAL STUDY; COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Name of substance:0 (Beta-Cryptoxanthin); 0 (Plant Extracts); 0 (Solvents); 0 (Zeaxanthins); 0 (oleoresins); 36-88-4 (Carotenoids)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM
[Da] Date of entry for processing:180126
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess17155

  2 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29521624
[Au] Autor:Coradetti ST; Pinel D; Geiselman G; Ito M; Mondo S; Reilly MC; Cheng YF; Bauer S; Grigoriev I; Gladden JM; Simmons BA; Brem R; Arkin AP; Skerker JM
[Ad] Address:The Buck Institute for Research on Aging, Novato, United States.
[Ti] Title:Functional genomics of lipid metabolism in the oleaginous yeast .
[So] Source:Elife;7, 2018 Mar 09.
[Is] ISSN:2050-084X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The basidiomycete yeast (a.k.a. ) accumulates high concentrations of lipids and carotenoids from diverse carbon sources. It has great potential as a model for the cellular biology of lipid droplets and for sustainable chemical production. We developed a method for high-throughput genetics (RB-TDNAseq), using sequence-barcoded T-DNA insertions. We identified 1337 putative essential genes with low T-DNA insertion rates. We functionally profiled genes required for fatty acid catabolism and lipid accumulation, validating results with 35 targeted deletion strains. We identified a high-confidence set of 150 genes affecting lipid accumulation, including genes with predicted function in signaling cascades, gene expression, protein modification and vesicular trafficking, autophagy, amino acid synthesis and tRNA modification, and genes of unknown function. These results greatly advance our understanding of lipid metabolism in this oleaginous species and demonstrate a general approach for barcoded mutagenesis that should enable functional genomics in diverse fungi.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  3 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29520458
[Au] Autor:Li G; Chen D; Tang X; Liu Y
[Ad] Address:School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei, 230009, China.
[Ti] Title:Heterologous expression of kiwifruit (Actinidia chinensis) GOLDEN2-LIKE homolog elevates chloroplast level and nutritional quality in tomato (Solanum lycopersicum).
[So] Source:Planta;, 2018 Mar 08.
[Is] ISSN:1432-2048
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:MAIN CONCLUSION: Constitutive expression of AchGLK from A. chinensis in transgenic tomato (S. lycopersicum) confers fruits an elevated plastid biogenesis with intensified granule thylakoid stacks and increased content of nutritional compounds. Plastid development is regulated by multiple environmental and genetic factors. Golden2-like (GLK) genes, members from GARP subfamily of the MYB transcription factors, have been shown to regulate plastid biogenesis and development in several species. In tomato (S. lycopersicum), SlGLK2 gene is expressed in the fruit in a manner of latitudinal gradient and determines the green shoulder phenotype. Here, we report the isolation and characterization of a kiwifruit (A. chinensis) GLK homolog (AchGLK). Transcription analysis showed that AchGLK is highly expressed in mature leaves and in fruits 60-day post-anthesis. Overexpression of AchGLK in transgenic tomato resulted in dark green immature fruit with higher concentration of chlorophyll and overall increased chloroplast compartment, both number and size. The ripened fruit had higher levels of carotenoids and sugars as well. Nevertheless, no phenotypic changes were observed in the transgenic leaves, similar to the previously described overexpression of SlGLK2 in tomato. Our study suggests that AchGLK is functionally homologous to tomato GLK2 with a potential in regulating plastid level in fruit that could contribute to improvement of fruit quality.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1007/s00425-018-2853-6

  4 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29518657
[Au] Autor:Rehman HU; Alharby HF; Alzahrani Y; Rady MM
[Ad] Address:Department of Agronomy, University of Agriculture, Faisalabad, 38040, Pakistan. Electronic address: h.rehman@uaf.edu.pk.
[Ti] Title:Magnesium and organic biostimulant integrative application induces physiological and biochemical changes in sunflower plants and its harvested progeny on sandy soil.
[So] Source:Plant Physiol Biochem;126:97-105, 2018 Mar 02.
[Is] ISSN:1873-2690
[Cp] Country of publication:France
[La] Language:eng
[Ab] Abstract:Magnesium (Mg) often leaches down in sandy soils due to high mobility and its foliar application proves to be beneficial. Organic biostimulants also prove to be helpful to affect plant physio-biochemistry and antioxidative defense system. The present study evaluated the beneficial effects of seed soaking in maize grain extract (MGE; 3%) in integration with or without foliar Mg (1 mM) in comparison to control (no treatment) on growth, yield performance, seed oil and fatty acid profile including physiological and biochemical basis of Hysun-336 sunflower hybrid grown on a sandy soil under greenhouse conditions. The integrative treatment (seed soaking in MGE + foliar spray with Mg) elevated growth traits, plant water status and membrane stability index, and reduced electrolyte leakage. Improved leaf contents of chlorophylls, carotenoids, total soluble sugars and proline, activities of non-enzymatic and enzymatic antioxidants were also observed. In addition, enhanced uptake of N, P, K including Mg and endogenous levels of plant hormones IAA, GA and zeatin were recorded with the integrative treatment. Seed yield and oil contents including oleic (mono-unsaturated) and linoleic (poly-unsaturated) fatty acids also increased; however, a decrease in other saturated, mono-unsaturated and poly-unsaturated fatty acids was noticed. Improved seed and seedling vigor traits were also observed in progeny of sunflower that harvested from the integrative treatment. In summary, improved plant performance by the integrative treatment may be attributed to improved activities of antioxidants contributing to improved plant water content, nutrient uptake and endogenous hormonal levels in sunflower plants grown under sandy soil conditions.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:Publisher

  5 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29458469
[Au] Autor:Cai H; Cui H; Zeng Y; An M; Jiang H
[Ad] Address:1​State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, PR China.
[Ti] Title:Sandarakinorhabdus cyanobacteriorum sp. nov., a novel bacterium isolated from cyanobacterial aggregates in a eutrophic lake.
[So] Source:Int J Syst Evol Microbiol;68(3):730-735, 2018 Mar.
[Is] ISSN:1466-5034
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:A bacterial strain, designated TH057 , was isolated from cyanobacterial aggregates in a eutrophic lake in China. Cells were observed to be slightly curved, rod-shaped, capsule-forming and stained Gram-negative. Optimal growth was obtained at pH 7.0 (range: pH 5-9) and 30 °C (range: 20-37 °C) in R2A broth. According to the absorption spectrum, carotenoids (455 and 490 nm) and light-harvesting complex LHI (857 nm) were present in the cells. The cells were found to be positive for oxidase and catalase activities. The major respiratory quinone was ubiquinone Q-10. The major fatty acids were identified as C17 : 1ω6c, C16 : 1ω7c/C16 : 1ω6c, C18 : 1ω6c/C18 : 1ω7c and C16 : 0. The major polar lipids were found to consist of phosphatidylethanolamine, diphosphatidylglycerol, phosphatidylglycerol, unidentified glycolipid and two sphingoglycolipids. Strain TH057 shared highest 16S rRNA gene sequence similarity to Sandarakinorhabdus limnophila so42 (96.8 %), followed by Polymorphobacter fuscus D40P (95.8 %). The genomic G+C content of strain TH057 was 66.1 mol% based on total genome calculations. The average nucleotide identity and the digital DNA-DNA hybridization value for the complete genomes were 81.0 and 23.0 % between strain TH057 and Sandarakinorhabdus limnophila so42 . The phenotypic, chemotaxonomic and phylogenetic properties, and genome analysis suggested that strain TH057 represents a novel species within the genus Sandarakinorhabdus, for which the name Sandarakinorhabduscyanobacteriorum sp. nov. is proposed. The type strain is TH057 (=CGMCC 1.15803 =LMG 30294 ).
[Mh] MeSH terms primary: Lakes/microbiology
Phylogeny
Sphingomonadaceae/classification
[Mh] MeSH terms secundary: Bacterial Typing Techniques
Base Composition
China
Cyanobacteria
DNA, Bacterial/genetics
Fatty Acids/chemistry
Nucleic Acid Hybridization
Phospholipids/chemistry
RNA, Ribosomal, 16S/genetics
Sequence Analysis, DNA
Sphingomonadaceae/genetics
Sphingomonadaceae/isolation & purification
Ubiquinone/chemistry
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phospholipids); 0 (RNA, Ribosomal, 16S); 1339-63-5 (Ubiquinone); I7T5V2W47R (Ubiquinone Q2)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:180221
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002571

  6 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29360387
[Au] Autor:Chang SK; Alasalvar C; Shahidi F
[Ad] Address:a Department of Nutrition and Dietetics , School of Health Sciences, International Medical University , Kuala Lumpur , Malaysia.
[Ti] Title:Superfruits: Phytochemicals, antioxidant efficacies, and health effects - A comprehensive review.
[So] Source:Crit Rev Food Sci Nutr;:1-25, 2018 Jan 23.
[Is] ISSN:1549-7852
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:The term "superfruit" has gained increasing usage and attention recently with the marketing strategy to promote the extraordinary health benefits of some exotic fruits, which may not have worldwide popularity. This has led to many studies with the identification and quantification of various groups of phytochemicals. This contribution discusses phytochemical compositions, antioxidant efficacies, and potential health benefits of the main superfruits such as açai, acerola, camu-camu, goji berry, jaboticaba, jambolão, maqui, noni, and pitanga. Novel product formulations, safety aspects, and future perspectives of these superfruits have also been covered. Research findings from the existing literature published within the last 10 years have been compiled and summarized. These superfruits having numerous phytochemicals (phenolic acids, flavonoids, proanthocyanidins, iridoids, coumarins, hydrolysable tannins, carotenoids, and anthocyanins) together with their corresponding antioxidant activities, have increasingly been utilized. Hence, these superfruits can be considered as a valuable source of functional foods due to the phytochemical compositions and their corresponding antioxidant activities. The phytochemicals from superfruits are bioaccessible and bioavailable in humans with promising health benefits. More well-designed human explorative studies are needed to validate the health benefits of these superfruits.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1080/10408398.2017.1422111

  7 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29221896
[Au] Autor:Kunitake JAMR; Choi S; Nguyen KX; Lee MM; He F; Sudilovsky D; Morris PG; Jochelson MS; Hudis CA; Muller DA; Fratzl P; Fischbach C; Masic A; Estroff LA
[Ad] Address:Department of Materials Science and Engineering, Cornell University, Ithaca, NY 14853, USA.
[Ti] Title:Correlative imaging reveals physiochemical heterogeneity of microcalcifications in human breast carcinomas.
[So] Source:J Struct Biol;202(1):25-34, 2018 Apr.
[Is] ISSN:1095-8657
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Microcalcifications (MCs) are routinely used to detect breast cancer in mammography. Little is known, however, about their materials properties and associated organic matrix, or their correlation to breast cancer prognosis. We combine histopathology, Raman microscopy, and electron microscopy to image MCs within snap-frozen human breast tissue and generate micron-scale resolution correlative maps of crystalline phase, trace metals, particle morphology, and organic matrix chemical signatures within high grade ductal carcinoma in situ (DCIS) and invasive cancer. We reveal the heterogeneity of mineral-matrix pairings, including punctate apatitic particles (<2 µm) with associated trace elements (e.g., F, Na, and unexpectedly Al) distributed within the necrotic cores of DCIS, and both apatite and spheroidal whitlockite particles in invasive cancer within a matrix containing spectroscopic signatures of collagen, non-collagen proteins, cholesterol, carotenoids, and DNA. Among the three DCIS samples, we identify key similarities in MC morphology and distribution, supporting a dystrophic mineralization pathway. This multimodal methodology lays the groundwork for establishing MC heterogeneity in the context of breast cancer biology, and could dramatically improve current prognostic models.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:In-Data-Review

  8 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29513632
[Au] Autor:Wannachod T; Wannasutthiwat S; Powtongsook S; Nootong K
[Ad] Address:a Chemical Engineering Research Unit for Valued-adding of Bioresource, Department of Chemical Engineering, Faculty of Engineering , Chulalongkorn University , Bangkok , Thailand.
[Ti] Title:Photoautotrophic cultivating options of freshwater green microalgal Chlorococcum humicola for biomass and carotenoids production.
[So] Source:Prep Biochem Biotechnol;, 2018 Mar 07.
[Is] ISSN:1532-2297
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Photoautotrophic cultivation of Chlorococcum humicola was performed in batch and continuous modes in different cultivating system arrangements to compare biomass and carotenoids concentration and their productivities. Batch result from stirred tank and airlift photobioreactors indicated the positive effect of increasing light intensity on growth and carotenoids production, whereas the finding from continuous cultivation indicated that carotenoids enhancement preferred high light intensity and nitrogen deficient environment. The highest biomass (1.31 ± 0.04 g L ) and carotenoids (4.59 ± 0.06 mg L ) concentration as well as the highest productivities, 0.46 g L d for biomass and 1.61 mg L d for carotenoids, were obtained when maintaining high light intensity of 10 klx, BG-11 medium and 2% v/v CO simultaneously, while the highest carotenoids content (4.84 mg g ) was associated with high light intensity and nitrogen deficient environment, which was induced by feed modified BG-11 growth medium containing nitrate 20 folds lower than the original medium. Finally, the cultivating system arranged into smaller stirred tank photobioreactors in series yielded approximately 2.5 folds increase of both biomass and carotenoids productivities relative to using single airlift photobioreactor with equivalent working volume and similar operating condition.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:Publisher
[do] DOI:10.1080/10826068.2018.1446152

  9 / 22373 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29378053
[Au] Autor:Jeon S; Ranard KM; Neuringer M; Johnson EE; Renner L; Kuchan MJ; Pereira SL; Johnson EJ; Erdman JW
[Ad] Address:Division of Nutritional Sciences and Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, IL.
[Ti] Title:Lutein Is Differentially Deposited across Brain Regions following Formula or Breast Feeding of Infant Rhesus Macaques.
[So] Source:J Nutr;148(1):31-39, 2018 Jan 01.
[Is] ISSN:1541-6100
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Background: Lutein, a yellow xanthophyll, selectively accumulates in primate retina and brain. Lutein may play a critical role in neural and retinal development, but few studies have investigated the impact of dietary source on its bioaccumulation in infants. Objective: We explored the bioaccumulation of lutein in infant rhesus macaques following breastfeeding or formula-feeding. Methods: From birth to 6 mo of age, male and female rhesus macaques (Macaca mulatta) were either breastfed (BF) (n = 8), fed a formula supplemented with lutein, zeaxanthin, ß-carotene, and lycopene (237, 19.0, 74.2, and 338 nmol/kg, supplemented formula-fed; SF) (n = 8), or fed a formula with low amounts of these carotenoids (38.6, 2.3, 21.5, and 0 nmol/kg, unsupplemented formula-fed; UF) (n = 7). The concentrations of carotenoids in serum and tissues were analyzed by HPLC. Results: At 6 mo of age, the BF group exhibited significantly higher lutein concentrations in serum, all brain regions, macular and peripheral retina, adipose tissue, liver, and other tissues compared to both formula-fed groups (P < 0.001). Lutein concentrations were higher in the SF group than in the UF group in serum and all tissues, with the exception of macular retina. Lutein was differentially distributed across brain areas, with the highest concentrations in the occipital cortex, regardless of the diet. Zeaxanthin was present in all brain regions but only in the BF infants; it was present in both retinal regions in all groups but was significantly enhanced in BF infants compared to either formula group (P < 0.001). ß-Carotene accumulated across brain regions in all groups, but was not detected in retina. Although lycopene was found in many tissues of the SF group, it was not detected in the brain or retina. Conclusions: Although carotenoid supplementation of infant formula significantly increased serum and tissue lutein concentrations compared to unsupplemented formula, concentrations were still well below those in BF infants. Regardless of diet, occipital cortex showed selectively higher lutein deposition than other brain regions, suggesting lutein's role in visual processing in early life.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Data-Review
[do] DOI:10.1093/jn/nxx023

  10 / 22373 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29325120
[Au] Autor:Kobae Y; Kameoka H; Sugimura Y; Saito K; Ohtomo R; Fujiwara T; Kyozuka J
[Ad] Address:Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657 Japan.
[Ti] Title:Strigolactone Biosynthesis Genes of Rice are Required for the Punctual Entry of Arbuscular Mycorrhizal Fungi into the Roots.
[So] Source:Plant Cell Physiol;59(3):544-553, 2018 Mar 01.
[Is] ISSN:1471-9053
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:Arbuscular mycorrhiza (AM) is a mutualistic association between most plant species and the ancient fungal phylum Glomeromycota in roots, and it plays a key role in a plant's nutrient uptake from the soil. Roots synthesize strigolactones (SLs), derivatives of carotenoids, and exude them to induce energy metabolism and hyphal branching of AM fungi. Despite the well-documented roles of SLs in the pre-symbiotic phase, little is known about the role of SLs in the process of root colonization. Here we show that the expansion of root colonization is suppressed in the mutants of rice (Oryza sativa) SL biosynthesis genes, carotenoid cleavage dioxygenase D10 and more severely in D17. Interestingly, most of the colonization process is normal, i.e. AM fungal hyphae approach the roots and cling around them, and epidermal penetration, arbuscule size, arbuscule number per hyphopodium and metabolic activity of the intraradical mycelium are not affected in d10 and d17 mutants. In contrast, hyphopodium formation is severely attenuated. Our observations establish the requirement for SL biosynthesis genes for efficient hyphopodium formation, suggesting that SLs are required in this process. Efficient hyphopodium formation is required for the punctual internalization of hyphae into roots and maintaining the expansion of colonization.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:In-Process
[do] DOI:10.1093/pcp/pcy001


page 1 of 2238 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information