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[PMID]: 29390503
[Au] Autor:Zhang D; Cao D; Shen D; Mulmi Shrestha S; Yin Y
[Ad] Address:Gastroenterology Department, Affiliated Zhongda Hospital of Southeast University, China.
[Ti] Title:Extramedullary plasmacytoma occuring in ileocecum: A case report and literature review.
[So] Source:Medicine (Baltimore);96(51):e9313, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:RATIONALE: Gastrointestinal solitary extramedullary plasmacytoma (EMP) is rare, just occupies about 5% of all EMPs. The most common site is small intestine followed by stomach. The colorectal incidence is much rare. PATIENT CONCERNS: A 63-year-old female had an episodic pain around the umbilicus for about one week. The hyperemia and edema in the ileocecal mucosa were found in colonoscopy, and the endoscopy could not cross the ileocecal valve. The pathology specimens showed a high index suspicion of plasmacytoma. DIAGNOSES: The patient was diagnosed with extramedullary plasmacytoma. INTERVENTIONS: A right hemicolectomy surgery was performed to treat the disease. OUTCOMES: Post surgery pathologic report showed low grade malignant mucosa associated marginal zone B cell lymphoma. LESSONS: We report a case of an extramedullary plasmacytoma in ileocecum with abdominal pain and a review of extramedullary plasmacytoma.
[Mh] MeSH terms primary: Cecal Neoplasms/pathology
Ileal Neoplasms/pathology
Plasmacytoma/pathology
[Mh] MeSH terms secundary: Cecal Neoplasms/surgery
Colectomy
Female
Humans
Ileal Neoplasms/surgery
Middle Aged
Plasmacytoma/surgery
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009313

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[PMID]: 29415338
[Au] Autor:Eberth JM; Thibault A; Caldwell R; Josey MJ; Qiang B; Peña E; LaFrance D; Berger FG
[Ad] Address:Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina.
[Ti] Title:A statewide program providing colorectal cancer screening to the uninsured of South Carolina.
[So] Source:Cancer;, 2018 Feb 07.
[Is] ISSN:1097-0142
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Cancer screening rates are lowest in those without insurance or a regular provider. Since 2008, the Colorectal Cancer Prevention Network (CCPN) has provided open access colonoscopy to uninsured residents of South Carolina through established, statewide partnerships and patient navigation. Herein, we describe the structure, implementation, and clinical outcomes of this program. METHODS: The CCPN provides access to colonoscopy screening at no cost to uninsured, asymptomatic patients aged 50-64 years (African Americans age 45-64 years are eligible) who live at or below 150% of the poverty line and seek medical care in free medical clinics, federally qualified health centers, or hospital-based indigent practices in South Carolina. Screening is performed by board-certified gastroenterologists. Descriptive statistics and regression analysis are used to describe the population screened, and to assess compliance rates and colonoscopy quality metrics. RESULTS: Out of >4000 patients referred to the program, 1854 were deemed eligible, 1144 attended an in-person navigation visit, and 1030 completed a colonoscopy; 909 were included in the final sample. Nearly 90% of participants exhibited good-to-excellent bowel preparation. An overall cecal intubation rate of 99% was measured. The polyp detection rate and adenoma detection rate were 63% and 36%, respectively, with male sex and urban residence positively associated with adenoma detection. Over 13% of participants had an advanced polyp, and 1% had a cancer diagnosis or surgical intervention. CONCLUSION: The CCPN program is characterized by strong collaboration with clinicians statewide, low no-show rates, and high colonoscopy quality. Future work will assess the effectiveness of the navigation approach and will explore the mechanisms driving higher adenoma detection in urban participants. Cancer 2018. © 2018 American Cancer Society.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180210
[Lr] Last revision date:180210
[St] Status:Publisher
[do] DOI:10.1002/cncr.31250

  3 / 3621 MEDLINE  
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[PMID]: 29283904
[Au] Autor:Núñez-Rodríguez H; Diez-Redondo P; Pérez-Miranda M; Gonzalez Sagrado M; Conde R; De la Serna C
[Ad] Address:Gastroenterology Department.
[Ti] Title:Role of Full-spectrum Endoscopy in Colorectal Cancer Screening: Randomized Trial.
[So] Source:J Clin Gastroenterol;, 2017 Dec 27.
[Is] ISSN:1539-2031
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:GOALS: The aim of this study was to compare a new, full-spectrum endoscope (Fuse; EndoChoice, Alpharetta, GA) to standard forward-viewing colonoscopy in the detection of colorectal neoplasms. BACKGROUND: Colonoscopy, the gold standard for the detection of colorectal cancer, fails to detect 22% to 28% of polyps, increasing the risk of interval cancer. Endoscopic improvement of the adenoma detection rate decrease interval carcinomas. Full-spectrum endoscopy (FUSE) (330-degree field of view), in a tandem study, has been shown to reduce the adenoma miss rate. STUDY: Prospective, randomized study of 249 patients in patients referred from the colorectal screening program with a positive fecal occult blood test (FOBT). Patients were randomized to standard forward-viewing colonoscopy (170 degrees) or to full-spectrum colonoscopy with the Fuse system (330 degrees). Study variables were the adenoma detection rate, the polyp detection rate, the mean number of adenomas per procedure, the lesions detected according to the location, morphology and size, cecal intubation rate, total procedure time, insertion time to the cecum, therapeutic success, and adverse events. RESULTS: The Fuse system did not produce a significantly higher adenoma detection rate than standard forward-viewing colonoscopy (FUSE 73.1% vs. standard colonoscopy 68.1%; P=0.47) but did have a significantly longer insertion time (FUSE 6.2 min vs. standard colonoscopy 4.2 min; P< 0.001). Further analysis failed to reveal any significant difference in polyp/adenoma detection rates by lesion size or colonic section. CONCLUSIONS: FUSE did not detect significantly more colorectal neoplasia than forward viewing colonoscopy in a medium-risk CRC screening population with positive FOBT.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1712
[Cu] Class update date: 180109
[Lr] Last revision date:180109
[St] Status:Publisher
[do] DOI:10.1097/MCG.0000000000000975

  4 / 3621 MEDLINE  
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[PMID]: 28742687
[Au] Autor:Limani P; Linecker M; Schneider MA; Kron P; Tschuor C; Kachaylo E; Ungethuem U; Nicolau C; Lehn JM; Graf R; Humar B; Clavien PA
[Ad] Address:*Department of Surgery and Transplantation, Swiss Hepato-pancreato-biliary (HPB) and Transplantation Laboratory, University Hospital Zurich, Zurich, Switzerland †Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA ‡Institute of Supramolecular Science and Engineering, University of Strasbourg, Strasbourg, France.
[Ti] Title:The Allosteric Hemoglobin Effector ITPP Inhibits Metastatic Colon Cancer in Mice.
[So] Source:Ann Surg;266(5):746-753, 2017 11.
[Is] ISSN:1528-1140
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE: To test the effects of enhanced intracellular oxygen contents on the metastatic potential of colon cancer. BACKGROUND: Colorectal cancer is the commonest gastrointestinal carcinoma. Distant metastases occur in half of patients and are responsible for most cancer-related deaths. Tumor hypoxia is central to the pathogenesis of metastases. Myo-Inositoltrispyrophosphate (ITPP), a nontoxic, antihypoxic compound, has recently shown significant benefits in experimental cancer, particularly when combined with standard chemotherapy. Whether ITPP protects from distant metastases in primary colon cancer is unknown. METHODS: ITPP alone or combined with FOLFOX was tested in a mouse model with cecal implantation of green fluorescent protein-labeled syngeneic colorectal cancer cells. Tumor development was monitored through longitudinal magnetic resonance imaging-based morphometric analysis and survival. Established serum markers of tumor spread were measured serially and circulating tumor cells were detected via fluorescence measurements. RESULTS: ITPP significantly reduced the occurrence of metastases as well as other indicators of tumor aggressiveness. Less circulating tumor cells along with reduction in malignant serum markers (osteopontin, Cxcl12) were noted. The ITPP benefits also affected the primary cancer site. Importantly, animals treated with ITPP had a significant survival benefit compared with respective controls, while a combination of FOLFOX with ITPP conferred the maximum benefits, including dramatic improvements in survival (mean 86 vs 188 d). CONCLUSIONS: Restoring oxygen in metastatic colon cancer through ITPP inhibits tumor spread and markedly improves animal survival; an effect that is enhanced through the application of subsequent chemotherapy. These promising novel findings call for a clinical trial on ITPP in patients with colorectal cancer, which is under way.
[Mh] MeSH terms primary: Antineoplastic Agents/therapeutic use
Colonic Neoplasms/drug therapy
Colonic Neoplasms/pathology
Inositol Phosphates/therapeutic use
Liver Neoplasms/prevention & control
Liver Neoplasms/secondary
[Mh] MeSH terms secundary: Animals
Antineoplastic Agents/pharmacology
Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Biomarkers, Tumor/blood
Colonic Neoplasms/blood
Colonic Neoplasms/mortality
Enzyme-Linked Immunosorbent Assay
Fluorouracil/therapeutic use
Immunohistochemistry
Inositol Phosphates/pharmacology
Leucovorin/therapeutic use
Liver Neoplasms/blood
Mice
Mice, Inbred C57BL
Neoplastic Cells, Circulating/drug effects
Organoplatinum Compounds/therapeutic use
Real-Time Polymerase Chain Reaction
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (Antineoplastic Agents); 0 (Biomarkers, Tumor); 0 (Inositol Phosphates); 0 (Organoplatinum Compounds); 0 (inositol trispyrophosphate); Q573I9DVLP (Leucovorin); U3P01618RT (Fluorouracil)
[Em] Entry month:1710
[Cu] Class update date: 171214
[Lr] Last revision date:171214
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170726
[St] Status:MEDLINE
[do] DOI:10.1097/SLA.0000000000002431

  5 / 3621 MEDLINE  
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[PMID]: 29081443
[Au] Autor:Iwamuro M; Yasuda M; Hasegawa K; Fujisawa S; Ogura-Ochi K; Sugihara Y; Harada K; Hiraoka S; Okada H; Otsuka F
[Ad] Address:Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
[Ti] Title:Colonoscopy examination requires a longer time in patients with acromegaly than in other individuals.
[So] Source:Endocr J;, 2017 Oct 28.
[Is] ISSN:1348-4540
[Cp] Country of publication:Japan
[La] Language:eng
[Ab] Abstract:This study aimed to determine the prevalence of colorectal neoplasms and to investigate the rate of and time required for cecal intubation in patients with acromegaly. A database search performed at our institution identified 29 patients with acromegaly who underwent colonoscopy. Data regarding the endoscopic, biological, and pathological examinations performed were retrospectively reviewed from the clinical records. Subsequently, the rate of and time required for cecal intubation were investigated in 23 patients with acromegaly and compared with the corresponding data of the control group. Control subjects were selected from a 2:1 matched historical control cohort, according to baseline characteristics. The mean age of the acromegaly group (17 female and 12 male) was 60.4 ± 12.6 years. Twelve patients had adenoma (41.4%), eight patients had hyperplastic polyps (27.6%), three patients had sessile serrated adenoma/polyps (10.3%), and three patients had colon cancer (10.3%). Successful cecal intubation was achieved in all patients in both groups. The difference in the time required for successful intubation between the acromegaly group (15.7 ± 9.8 minutes) and the control group (8.7 ± 6.0 minutes) was statistically significant. Linear regression analysis revealed that increased patient age was significantly related to longer colonoscope insertion times. In conclusion, although cecal intubation during colonoscopy was successful in all participants, it required a longer time in patients with acromegaly. Our results underscore the importance of and certain technical difficulties involved in colonoscopy procedures in patients with acromegaly, especially in older patients.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171030
[Lr] Last revision date:171030
[St] Status:Publisher
[do] DOI:10.1507/endocrj.EJ17-0322

  6 / 3621 MEDLINE  
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[PMID]: 28936593
[Au] Autor:Song EM; Yang HJ; Lee HJ; Lee HS; Cha JM; Kim HG; Jung Y; Moon CM; Kim BC; Byeon JS
[Ad] Address:Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
[Ti] Title:Endoscopic Resection of Cecal Polyps Involving the Appendiceal Orifice: A KASID Multicenter Study.
[So] Source:Dig Dis Sci;62(11):3138-3148, 2017 Nov.
[Is] ISSN:1573-2568
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Endoscopic resection of polyps located at the appendiceal orifice (AO) is challenging, and the feasibility and outcomes of endoscopic resection for cecal polyps involving AO are unconfirmed. AIMS: We evaluated the feasibility and outcomes of endoscopic resection for cecal polyps involving AO. METHODS: In this retrospective, multicenter study involving nine tertiary referral centers, we evaluated 131 patients who underwent endoscopic resection for cecal polyps involving AO. RESULTS: The median size of polyps resected was 10 mm (range 3-60 mm). Endoscopic mucosal resection, endoscopic piecemeal mucosal resection, and endoscopic submucosal dissection were performed in 75 (57.3%), 31 (23.7%), and 5 (3.8%) patients, respectively. The en bloc resection rate was 68.7%. Endoscopic complete resection was achieved in 123 lesions (93.9%). Intraprocedural and delayed bleeding occurred in 14 (10.7%) and three patients (2.3%), respectively, and perforation occurred in two patients (1.5%). Seven patients (5.3%) underwent additional surgery because of treatment failure or recurrence. Polyps of ≥20 mm in size showed significantly higher rates of perforation and additional surgery (p < 0.05), and a lower rate of en bloc resection (p < 0.005). Patients with polyps involving ≥75% of AO circumference exhibited a significantly lower rate of en bloc resection (p < 0.001), and significantly higher rates of surgery and recurrence (p < 0.05). Recurrence during follow-up occurred in 12 patients (15.6%); polyps involving ≥75% of AO circumference were an independent risk factor for recurrence. CONCLUSION: Endoscopic resection of cecal polyps involving AO is safe and effective in select patients.
[Mh] MeSH terms primary: Appendiceal Neoplasms/surgery
Cecal Neoplasms/surgery
Endoscopic Mucosal Resection/methods
Intestinal Polyps/surgery
[Mh] MeSH terms secundary: Adult
Aged
Aged, 80 and over
Appendiceal Neoplasms/pathology
Cecal Neoplasms/pathology
Endoscopic Mucosal Resection/adverse effects
Feasibility Studies
Female
Humans
Intestinal Polyps/pathology
Male
Middle Aged
Postoperative Complications/etiology
Postoperative Complications/surgery
Republic of Korea
Retrospective Studies
Risk Factors
Tertiary Care Centers
Time Factors
Treatment Outcome
Tumor Burden
[Pt] Publication type:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Entry month:1711
[Cu] Class update date: 171106
[Lr] Last revision date:171106
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:170923
[St] Status:MEDLINE
[do] DOI:10.1007/s10620-017-4760-2

  7 / 3621 MEDLINE  
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[PMID]: 28848785
[Au] Autor:Oliveira Ferreira A; Fidalgo C; Palmela C; Costa Santos MP; Torres J; Nunes J; Loureiro R; Ferreira R; Barjas E; Glória L; Santos AA; Cravo M
[Ad] Address:Gastroenterology Department, Hospital Beatriz Ângelo, Loures, Portugal.
[Ti] Title:Adenoma Detection Rate: I Will Show You Mine if You Show Me Yours.
[So] Source:GE Port J Gastroenterol;24(2):61-67, 2017 Mar.
[Is] ISSN:2341-4545
[Cp] Country of publication:Switzerland
[La] Language:eng
[Ab] Abstract:BACKGROUND: Colorectal cancer (CRC) is the first cause of cancer-related mortality in Portugal. CRC screening reduces disease-specific mortality. Colonoscopy is currently the preferred method for screening as it may contribute to the reduction of CRC incidence. This beneficial effect is strongly associated with the adenoma detection rate (ADR). AIM: Our aim was to evaluate the quality of colonoscopy at our unit by measuring the currently accepted quality parameters and publish them as benchmarking indicators. METHODS: From 5,860 colonoscopies, 654 screening procedures (with and without previous fecal occult blood testing) were analyzed. RESULTS: The mean age of the patients was 66.4 ± 7.8 years, and the gender distribution was 1:1. The overall ADR was 36% (95% confidence interval [CI] 32-39), the mean number of adenomas per colonoscopy was 0.66 (95% CI 0.56-0.77), and the sessile serrate lesion detection rate was 1% (95% CI 0-2). The bowel preparation was rated as adequate in 496 (76%) patients. The adjusted cecal intubation rate (CIR) was 93.7% (95% CI 91.7-95.8). Most colonoscopies were performed under monitored anesthesia care (53%), and 35% were unsedated. The use of sedation (propofol or midazolam based) was associated with a higher CIR with an odds ratio of 3.60 (95% CI 2.02-6.40, < 0.001). CONCLUSION: Our data show an above-standard ADR. The frequency of poor bowel preparation and the low sessile serrated lesion detection rate were acknowledged, and actions were implemented to improve both indicators. Quality auditing in colonoscopy should be compulsory, and while many units may do so internally, this is the first national report from a high-throughput endoscopy unit.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 170902
[Lr] Last revision date:170902
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.1159/000450901

  8 / 3621 MEDLINE  
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[PMID]: 28661219
[Au] Autor:Yang Y; Nirmagustina DE; Kumrungsee T; Okazaki Y; Tomotake H; Kato N
[Ad] Address:a Graduate School of Biosphere Science , Hiroshima University , Higashi-Hiroshima , Japan.
[Ti] Title:Feeding of the water extract from Ganoderma lingzhi to rats modulates secondary bile acids, intestinal microflora, mucins, and propionate important to colon cancer.
[So] Source:Biosci Biotechnol Biochem;81(9):1796-1804, 2017 Sep.
[Is] ISSN:1347-6947
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Consumption of reishi mushroom has been reported to prevent colon carcinogenesis in rodents, although the underlying mechanisms remain unclear. To investigate this effect, rats were fed a high-fat diet supplemented with 5% water extract from either the reishi mushroom (Ganoderma lingzhi) (WGL) or the auto-digested reishi G. lingzhi (AWGL) for three weeks. Both extracts markedly reduced fecal secondary bile acids, such as lithocholic acid and deoxycholic acid (colon carcinogens). These extracts reduced the numbers of Clostridium coccoides and Clostridium leptum (secondary bile acids-producing bacteria) in a per g of cecal digesta. Fecal mucins and cecal propionate were significantly elevated by both extracts, and fecal IgA was significantly elevated by WGL, but not by AWGL. These results suggest that the reishi extracts have an impact on colon luminal health by modulating secondary bile acids, microflora, mucins, and propionate that related to colon cancer.
[Mh] MeSH terms primary: Bile Acids and Salts/metabolism
Colonic Neoplasms
Ganoderma/chemistry
Gastrointestinal Microbiome/drug effects
Mucins/metabolism
Propionates/metabolism
Water/chemistry
[Mh] MeSH terms secundary: Animals
Body Weight/drug effects
Cecum/drug effects
Cecum/microbiology
Colonic Neoplasms/metabolism
Colonic Neoplasms/microbiology
Diet
Eating/drug effects
Fatty Acids, Volatile/metabolism
Feces/chemistry
Immunoglobulin A/metabolism
Male
Rats
Rats, Sprague-Dawley
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Bile Acids and Salts); 0 (Fatty Acids, Volatile); 0 (Immunoglobulin A); 0 (Mucins); 0 (Propionates); 059QF0KO0R (Water)
[Em] Entry month:1709
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[Js] Journal subset:IM
[Da] Date of entry for processing:170630
[St] Status:MEDLINE
[do] DOI:10.1080/09168451.2017.1343117

  9 / 3621 MEDLINE  
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[PMID]: 28591173
[Au] Autor:Valasek MA; Thung I; Gollapalle E; Hodkoff AA; Kelly KJ; Baumgartner JM; Vavinskaya V; Lin GY; Tipps AP; Hosseini MV; Lowy AM
[Ad] Address:Department of Pathology, Division of Anatomic Pathology, University of California San Diego Medical Center, San Diego, California, United States of America.
[Ti] Title:Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care.
[So] Source:PLoS One;12(6):e0179216, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:CONTEXT: Low-grade appendiceal mucinous neoplasm (LAMN) and appendiceal adenocarcinoma are known to cause the majority of pseudomyxoma peritonei (PMP, i.e. mucinous ascites); however, recognition and proper classification of these neoplasms can be difficult despite established diagnostic criteria. OBJECTIVE: To determine the pathological diagnostic concordance for appendix neoplasia and related lesions during patient referral to an academic medical center specialized in treating patients with PMP. DESIGN: The anatomic pathology laboratory information system was searched to identify cases over a two-year period containing appendix specimens with mucinous neoplasia evaluated by an outside pathology group and by in-house slide review at a single large academic medical center during patient referral. RESULTS: 161 cases containing appendix specimens were identified over this period. Forty-six of 161 cases (28.6%) contained appendiceal primary neoplasia or lesions. Of these, the originating pathologist diagnosed 23 cases (50%) as adenocarcinoma and 23 cases (50%) as LAMN; however, the reference pathologist diagnosed 29 cases (63.0%) as LAMN, 13 cases (28.3%) as adenocarcinoma, and 4 cases (8.7%) as ruptured simple mucocele. Importantly, for cases in which the originating pathologist rendered a diagnosis of adenocarcinoma, the reference pathologist rendered a diagnosis of adenocarcinoma (56.5%, 13 of 23), LAMN (39.1%, 9 of 23), or simple mucocele (4.3%, 1 of 23). The overall diagnostic concordance rate for these major classifications was 71.7% (33 of 46) with an unweighted observed kappa value of 0.48 (95% CI, 0.27-0.69), consistent with moderate interobserver agreement. All of the observed discordance (28.3%) for major classifications could be attributed to over-interpretation. In addition, the majority of LAMN cases (65.5%) had potential diagnostic deficiencies including over-interpretation as adenocarcinoma and lacking or discordant risk stratification (i.e. documentation of extra-appendiceal neoplastic epithelium). CONCLUSIONS: Appendiceal mucinous lesions remain a difficult area for appropriate pathological classification with substantial discordance due to over-interpretation in this study. The findings highlight the critical need for recognition and application of diagnostic criteria regarding these tumors. Recently published consensus guidelines and a checklist provided herein may help facilitate improvement of diagnostic concordance and thereby reduce over-interpretation and potential overtreatment. Further studies are needed to determine the extent of this phenomenon and its potential clinical impact.
[Mh] MeSH terms primary: Adenocarcinoma, Mucinous/diagnosis
Appendiceal Neoplasms/diagnosis
Pseudomyxoma Peritonei/diagnosis
[Mh] MeSH terms secundary: Adenocarcinoma, Mucinous/classification
Adenocarcinoma, Mucinous/physiopathology
Adult
Aged
Aged, 80 and over
Appendiceal Neoplasms/classification
Appendiceal Neoplasms/physiopathology
Appendix/pathology
Clinical Laboratory Information Systems
Female
Humans
Male
Middle Aged
Neoplasm Grading
Pseudomyxoma Peritonei/classification
Pseudomyxoma Peritonei/physiopathology
Referral and Consultation
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170913
[Lr] Last revision date:170913
[Js] Journal subset:IM
[Da] Date of entry for processing:170608
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179216

  10 / 3621 MEDLINE  
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[PMID]: 28537568
[Au] Autor:Janczak D; Szponder M; Janczak D; Lesniak M; Ziomek A; Chabowski M
[Ad] Address:1 Department of Surgical Specialties, Faculty of Health Science, Wroclaw Medical University; Head: Prof. Dariusz Janczak, MD PhD.
[Ti] Title:Mucinous cystadenoma of the appendix - case report.
[So] Source:Pol Przegl Chir;89(2):65-68, 2017 Apr 30.
[Is] ISSN:2299-2847
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Tumors of the appendix are extremely rare and constitute about 0.4% of all tumors of the gastrointestinal tract. The most common benign neoplasm is mucinous cystadenoma, which can be found in 0.6% of all excised appendices and it rarely produces any symptoms. We present the case of a female patient who underwent surgery in the Department of Surgery due to suspicion of an appendicular abscess. On the postoperative pathology study, the diagnosis of a tumor of the appendix (mucinous cystadenoma) was made. Mucinous cystadenoma is rarely included in the differential diagnosis of a non-specific abdominal pain accompanied by non-characteristic laboratory test results and imaging studies. There are no unequivocal guidelines and algorithms of managing this disease. Long-term prognosis is good in the case of a benign tumor.
[Mh] MeSH terms primary: Appendiceal Neoplasms/diagnosis
Cystadenoma, Mucinous/diagnosis
[Mh] MeSH terms secundary: Aged
Appendectomy
Appendiceal Neoplasms/surgery
Appendix/pathology
Appendix/surgery
Cystadenoma, Mucinous/surgery
Female
Humans
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171109
[Lr] Last revision date:171109
[Js] Journal subset:IM
[Da] Date of entry for processing:170525
[St] Status:MEDLINE
[do] DOI:10.5604/01.3001.0009.9160


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