Database : MEDLINE
Search on : central and nervous and system and venous and angioma [Words]
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[PMID]: 29054771
[Au] Autor:Oda K; Morimoto D; Kim K; Yui K; Kitamura T; Morita A
[Ad] Address:Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan. Electronic address: kazu.nms7023@gmail.com.
[Ti] Title:Spinal cavernous angioma associated with Klippel-Trenaunay-Weber syndrome: a case report and literature review.
[So] Source:World Neurosurg;, 2017 Oct 17.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Klippel-Trenaunay-Weber syndrome (KTWS) is a rare congenital vascular disorder characterized by the classic triad of cutaneous nevi, venous varicosities, and osseous and soft tissue hypertrophy of the affected limb. Various vascular anomalies of the central nervous system have also been described in patients with this syndrome. The English-language literature to date contains six reports of associations between KTWS and spinal cord cavernous angioma (CA), but the management of these patients has not been well described. A 23-year-old woman was admitted to our institute because of acute onset of leg weakness accompanied by upper back pain. Thoracic magnetic resonance imaging showed a heterogeneous mass with a slit component at the T1/2 level of the spinal cord. After the patient underwent left hemilaminectomy followed by removal of the tumor, her neurological symptoms improved. Pathological examination showed that the spinal lesion was characterized by hemosiderin deposition and thin-walled vascular channels surrounded by fibrous tissue. This is the first report to provide a detailed pathological description of the features of a spinal CA in a patient with KTWS. The discussion includes an assessment of the clinical features and management of CA associated with KTWS. Because this syndrome is a rare disease entity, further experience in the treatment of these patients is needed. However, considering that the pathological findings of spinal CA in patients with KTWS include the typical features of CA, the management of CA in patients with KTWS may be identical to that of isolated CA.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171021
[Lr] Last revision date:171021
[St] Status:Publisher

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[PMID]: 28415057
[Au] Autor:Sakakibara Y; Taguchi Y; Nakamura H; Onodera H; Uchida M; Kawaguchi K; Aida Y
[Ad] Address:Division of Neurosurgery, St Marianna University School of Medicine, Yokohama City Seibu Hospital.
[Ti] Title:[De Novo Cavernous Angioma Secondary to a Developmental Venous Anomaly:A Case Report and Review of the Literature].
[So] Source:No Shinkei Geka;45(4):325-331, 2017 Apr.
[Is] ISSN:0301-2603
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:OBJECTIVE: Previously, cavernous angiomas(CAs)have been thought to be only congenital in origin. Recently, however, a few cases of de novo CAs have been reported in the literature. We present a case of a de novo CA and discuss the etiology of the newly appeared CA. CASE REPORT: A 29-year-old man was presented to a local clinic because of hypersomnia. MRI demonstrated a heterogeneous mass peripherally located, which was in contact with a developmental venous anomaly(DVA)at the left thalamus. Six years before the presentation, he visited the same clinic because of faintness, and MRI results indicated no abnormality except for the DVA. Three weeks later, he suddenly experienced difficulty in speech, and the MRI revealed an increase in the size of the mass. Subsequently, he was admitted at our institution, and neurological examination revealed aphasia and right hemiparesis. A left carotid angiogram on venous phase showed a narrowing of the DVA, which was seen as it entered the internal cerebral vein. The diagnosis of a de novo CA was made. The mass was completely resected through the transcallosal transventricular approach to avoid injuring the DVA. The DVA could not be found during surgery. The pathological diagnosis was in line with the findings of CA. Postoperatively, the patient continued having difficulty in speech and was transferred to another institution for speech rehabilitation. CONCLUSIONS: Although the association of CA and DVA has been described with increasing frequencies recently, the etiology of de novo CA in the case of this association has been a matter of debate. In the present case, it was speculated that a narrowing of the DVA resulted in increased venous pressure and caused the development of de novo CA.
[Mh] MeSH terms primary: Central Nervous System Vascular Malformations/surgery
Cerebellum/surgery
Cerebral Veins/abnormalities
Hemangioma, Cavernous/surgery
Magnetic Resonance Imaging
[Mh] MeSH terms secundary: Adult
Central Nervous System Vascular Malformations/diagnosis
Cerebellum/blood supply
Hemangioma, Cavernous/diagnosis
Hemangioma, Cavernous/pathology
Humans
Male
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Entry month:1708
[Cu] Class update date: 170831
[Lr] Last revision date:170831
[Js] Journal subset:IM
[Da] Date of entry for processing:170418
[St] Status:MEDLINE
[do] DOI:10.11477/mf.1436203503

  3 / 223 MEDLINE  
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[PMID]: 28291420
[Au] Autor:Brinjikji W; Flemming KD; Lanzino G
[Ad] Address:Departments of 1 Radiology.
[Ti] Title:De novo formation of a large cavernoma associated with a congenital torcular dural arteriovenous fistula: case report.
[So] Source:J Neurosurg Pediatr;19(5):567-570, 2017 May.
[Is] ISSN:1933-0715
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:The authors report a case of a developmentally normal child with a congenital complex torcular dural arteriovenous fistula (DAVF) who later, in his teenage years, developed several vermian cavernomas within a large cerebellar developmental venous anomaly (DVA). The patient had initially presented with an abnormally large head circumference but no neurological deficits. He underwent several partial embolization procedures in an attempt to decrease the blood supply of the fistula over the course of 8 years. Nine years following initial presentation, he presented with a fourth ventricular hemorrhage, due to development of a new vermian cavernoma adjacent to a previously known vermian DVA and suffered subsequent mild left-sided hemiataxia from which he later recovered. CT angiographic images demonstrated that the vermian DVA drained into the left transverse sinus, which also drained the torcular arteriovenous fistula. A routine follow-up MRI examination 10 years following initial presentation demonstrated interval development of several large cavernomas in the cerebellum, all within the DVA. The patient had no new symptoms at that time and was neurologically intact. This case report highlights the de novo development of multiple cavernous malformations potentially secondary to DAVF-induced venous congestion in a preexisting DVA.
[Mh] MeSH terms primary: Central Nervous System Vascular Malformations/complications
Cerebellum/abnormalities
Cerebellum/blood supply
Hemangioma, Cavernous, Central Nervous System/complications
[Mh] MeSH terms secundary: Adolescent
Ataxia/diagnostic imaging
Ataxia/etiology
Ataxia/therapy
Central Nervous System Vascular Malformations/diagnostic imaging
Central Nervous System Vascular Malformations/therapy
Cerebellum/diagnostic imaging
Cerebral Hemorrhage/diagnostic imaging
Cerebral Hemorrhage/etiology
Cerebral Hemorrhage/therapy
Embolization, Therapeutic
Hemangioma, Cavernous, Central Nervous System/diagnostic imaging
Hemangioma, Cavernous, Central Nervous System/therapy
Humans
Male
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1705
[Cu] Class update date: 170526
[Lr] Last revision date:170526
[Js] Journal subset:IM
[Da] Date of entry for processing:170315
[St] Status:MEDLINE
[do] DOI:10.3171/2016.12.PEDS16600

  4 / 223 MEDLINE  
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[PMID]: 28212190
[Au] Autor:Lampugnani MG; Malinverno M; Dejana E; Rudini N
[Ad] Address:aFondazione Italiana per la Ricerca sul Cancro (FIRC) Institute of Molecular Oncology Fondazione bMario Negri Institute for Pharmacological Research, Milan, Italy cDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden dDepartment of Biosciences, School of Sciences and Department of Oncology, School of Medicine, Milano University, Milan, Italy.
[Ti] Title:Endothelial cell disease: emerging knowledge from cerebral cavernous malformations.
[So] Source:Curr Opin Hematol;24(3):256-264, 2017 May.
[Is] ISSN:1531-7048
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE OF REVIEW: Endothelial cells dysfunctions are crucial determinants of several human diseases. We review here the most recent reports on endothelial cell defects in cerebral cavernous malformations (CCMs), particularly focusing on adherens junctions. CCM is a vascular disease that affects specifically the venous microvessels of the central nervous system and which is caused by loss-of-function mutation in any one of the three CCM genes (CCM1, 2 or 3) in endothelial cells. The phenotypic result of these mutations are focal vascular malformations that are permeable and fragile causing neurological symptoms and occasionally haemorrhagic stroke. RECENT FINDINGS: CCM is still an incurable disease, as no pharmacological treatment is available, besides surgery. The definition of the molecular alterations ensuing loss of function mutation of CCM genes is contributing to orientate the testing of targeted pharmacological tools.Several signalling pathways are altered in the three genotypes in a similar way and concur in the acquisition of mesenchymal markers in endothelial cells. However, also genotype-specific defects are reported, in particular for the CCM1 and CCM3 mutation. SUMMARY: Besides the specific CCM disease, the characterization of endothelial alterations in CCM has the potentiality to shed light on basic molecular regulations as the acquisition and maintenance of organ and vascular site specificity of endothelial cells.
[Mh] MeSH terms primary: Endothelial Cells/metabolism
Hemangioma, Cavernous, Central Nervous System/etiology
Hemangioma, Cavernous, Central Nervous System/metabolism
[Mh] MeSH terms secundary: Adherens Junctions/metabolism
Angiopoietins/metabolism
Animals
Biomarkers
Exocytosis
Hemangioma, Cavernous, Central Nervous System/pathology
Humans
Proto-Oncogene Proteins/genetics
Proto-Oncogene Proteins/metabolism
Signal Transduction
Transcription Factors/metabolism
Translational Medical Research
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Nm] Name of substance:0 (Angiopoietins); 0 (Biomarkers); 0 (Proto-Oncogene Proteins); 0 (Transcription Factors)
[Em] Entry month:1710
[Cu] Class update date: 171024
[Lr] Last revision date:171024
[Js] Journal subset:IM
[Da] Date of entry for processing:170218
[St] Status:MEDLINE
[do] DOI:10.1097/MOH.0000000000000338

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[PMID]: 27988892
[Au] Autor:Ortiz-Prieto A; Bernabeu-Wittel J; Zulueta-Dorado T; Lorente-Lavirgen AI; Muñoz M
[Ad] Address:Department of Dermatology, Virgen del Rocio University Hospital, Seville, Spain.
[Ti] Title:Immunolocalization of substance P and NK-1 receptor in vascular anomalies.
[So] Source:Arch Dermatol Res;309(2):97-102, 2017 Mar.
[Is] ISSN:1432-069X
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:The peptide substance P (SP) shows a widespread distribution in both the central and peripheral nervous systems, but it is also ubiquitous in the human body. After binding to the neurokinin-1 (NK-1) receptor, SP regulates tumoral angiogenesis and proliferation. Thus, knowledge of this system is the key for a better understanding and, hence, a better management of many human diseases, including vascular anomalies (VA). This study aims to examine the expression and localization of both SP and the NK-1 receptor in different vascular anomalies using an immunohistochemical technique. Our results demonstrated predominantly nuclear localization of SP in venous malformations and in one haemangioma sample, in contrast with cytoplasmic expression in capillary malformations and rapidly involuting congenital hemangioma (RICH). NK-1 receptor showed a cytoplasmic localization in all VA. In summary, all these findings demonstrate that SP and NK-1 receptor are expressed in VA, with different expression patterns depending on the nature of the anomaly, suggesting that they could play an important role in the pathogenesis of VA.
[Mh] MeSH terms primary: Receptors, Neurokinin-1/metabolism
Substance P/metabolism
Vascular Malformations/pathology
[Mh] MeSH terms secundary: Adolescent
Child
Child, Preschool
Female
Hemangioma/diagnosis
Hemangioma/pathology
Humans
Infant
Male
Protein Binding
Vascular Malformations/diagnosis
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Receptors, Neurokinin-1); 33507-63-0 (Substance P)
[Em] Entry month:1703
[Cu] Class update date: 170321
[Lr] Last revision date:170321
[Js] Journal subset:IM
[Da] Date of entry for processing:161219
[St] Status:MEDLINE
[do] DOI:10.1007/s00403-016-1707-y

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[PMID]: 27637648
[Au] Autor:Kaku Y; Takei H; Miyai M; Yamashita K; Kokuzawa J
[Ad] Address:Department of Neurosurgery, Asahi University Murakami Memorial Hospital, Gifu, Japan. kaku@murakami.asahi-u.ac.jp.
[Ti] Title:Surgical Approach to Ponto-mesencephalic Cavernoma.
[So] Source:Acta Neurochir Suppl;123:189-95, 2016.
[Is] ISSN:0065-1419
[Cp] Country of publication:Austria
[La] Language:eng
[Ab] Abstract:BACKGROUND AND AIMS: The surgical treatment of intrinsic brainstem lesions remains a major challenge. In this article we present the results of using an infratentorial-supracerebellar (ITSC) approach for the resection of intrinsic ponto-mesencephalic lesions. MATERIALS AND METHODS: The authors reviewed the cases of 16 patients. In seven of them, a paramedian ITSC transcollicular approach was used to resect intrinsic mid-brain lesions, and in the other nine patients, an intermediate or lateral ITSC infra-trochlear approach was used for ponto-mesencephalic lesions. RESULTS: All 16 lesions were completely removed. There was no recurrence of bleeding during the follow-up period, and no mortality. In seven patients with mid-brain lesions, the preoperative ocular symptoms improved in three of them, and the neurological deficits - other than ocular symptoms improved - in five of them. The preoperative modified Rankin Scale score of 1.8 improved to 1.3 postoperatively. In nine patients with a ponto-mesencephalic lesion, the preoperative ocular symptoms improved in four of nine patients, and the neurological deficits other than ocular symptoms improved in five of them, while one patient exhibited venous infarction in a cerebellar hemisphere that caused neurological deterioration. The preoperative modified Rankin Scale score of 3.75 improved to 2.5 postoperatively in these patients. CONCLUSION: The ITSC transcollicular or infra-trochlear approach provide a wide operative entry zone and minimize the functional damage to the surrounding structures for access to ponto-mesencephalic lesions.
[Mh] MeSH terms primary: Brain Stem Neoplasms/surgery
Hemangioma, Cavernous, Central Nervous System/surgery
Neurosurgical Procedures/methods
[Mh] MeSH terms secundary: Brain Stem Neoplasms/complications
Brain Stem Neoplasms/diagnostic imaging
Female
Hemangioma, Cavernous, Central Nervous System/complications
Hemangioma, Cavernous, Central Nervous System/diagnostic imaging
Humans
Intracranial Hemorrhages/etiology
Magnetic Resonance Imaging
Male
Middle Aged
Patient Positioning/methods
Retrospective Studies
Treatment Outcome
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171011
[Lr] Last revision date:171011
[Js] Journal subset:IM
[Da] Date of entry for processing:160918
[St] Status:MEDLINE
[do] DOI:10.1007/978-3-319-29887-0_27

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[PMID]: 27610183
[Au] Autor:Kim BR; Lee YJ; Nam SO; Park KH
[Ad] Address:Department of Pediatrics, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
[Ti] Title:Venous angioma may be associated with epilepsy in children.
[So] Source:Korean J Pediatr;59(8):341-5, 2016 Aug.
[Is] ISSN:1738-1061
[Cp] Country of publication:Korea (South)
[La] Language:eng
[Ab] Abstract:PURPOSE: Venous angioma (VA) is the most common congenital abnormality of the intracranial vasculature. This study aimed to investigate the relationship between VA and epilepsy and to identify the characteristics of children with VA and epilepsy. METHODS: The records of all patients aged less than 18 years who underwent brain magnetic resonance imaging (MRI) at Pusan National University Hospital were retrospectively reviewed. Patients with isolated VA and patients with normal MRI were compared in terms of the prevalence of epilepsy. RESULTS: In total, 2,385 pediatric patients who underwent brain MRI were enrolled. Isolated VA was identified in 26 patients (VA group). Among the patients with normal MRI findings, 225 age- and sex-matched patients to the VA-group were assigned to the control group. Nine patients in the VA group (9 of 26, 34.6%) and 27 patients in the control group (26 of 225, 11.5%; P<0.001) had epilepsy. In the VA group, 20 patients (76.9%) had the VA in the cerebral hemispheres, and 6 patients (23.1%) had the VA in the brainstem and cerebellum. The latter showed a higher prevalence of epilepsy (5 of 6, 83.3%) than the former (4 of 20, 20.0%; P=0.004). Among the nine patients who had epilepsy with VA, patients whose VA involved the brainstem and cerebellum showed a significantly higher frequency of abnormal Electroencephalographic findings than patients whose VA involved the cerebral hemispheres (P=0.016). CONCLUSION: VA, especially in the brainstem and cerebellum, might be associated with epilepsy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1609
[Cu] Class update date: 170224
[Lr] Last revision date:170224
[Da] Date of entry for processing:160910
[St] Status:PubMed-not-MEDLINE
[do] DOI:10.3345/kjp.2016.59.8.341

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[PMID]: 27562580
[Au] Autor:Chakravarthy H; Lin TK; Chen YL; Wu YM; Yeh CH; Wong HF
[Ad] Address:Sapthagiri Institute of Medical Sciences and Research Centre, India.
[Ti] Title:De novo formation of cerebral cavernous malformation adjacent to existing developmental venous anomaly - an effect of change in venous pressure associated with management of a complex dural arterio-venous fistula.
[So] Source:Neuroradiol J;29(6):458-464, 2016 Dec.
[Is] ISSN:2385-1996
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:This is a case report of de novo development of two cerebral cavernous malformations adjacent to existing developmental venous anomalies. The development of cavernomas was noted over a follow-up period of 10 years. These developments happened during the course of staged endovascular management of a complex dural arterio-venous fistula along the right sphenoid wing. The patient presented with a proptosis secondary to lympho-haemangiomatous lesion of the fronto-orbital region and a high-flow right sphenoid wing dural arterio-venous fistula. During the initial period of conservative management of the dural arterio-venous fistula, he developed de novo cavernous malformations in the left mesial temporal lobe adjacent to a developmental venous anomaly in the temporal lobe, and along with this there was engorgement of deep veins related to another existing developmental venous anomaly in the brainstem. Later during the course of endovascular treatment of the dural arterio-venous fistula, a large brainstem cavernoma developed adjacent to the brainstem developmental venous anomaly. This case report discusses the cause-effect relationship of venous pressure changes related to management of dural arterio-venous fistula and de novo formation of cerebral cavernous malformations adjacent to existing developmental venous anomalies.
[Mh] MeSH terms primary: Arteriovenous Fistula/complications
Central Nervous System Vascular Malformations/complications
Intracranial Arteriovenous Malformations/complications
Venous Pressure/physiology
[Mh] MeSH terms secundary: Adult
Angiography, Digital Subtraction
Arteriovenous Fistula/diagnostic imaging
Arteriovenous Fistula/surgery
Central Nervous System Vascular Malformations/diagnostic imaging
Central Nervous System Vascular Malformations/surgery
Disease Progression
Embolization, Therapeutic
Humans
Intracranial Arteriovenous Malformations/diagnostic imaging
Intracranial Arteriovenous Malformations/therapy
Longitudinal Studies
Magnetic Resonance Imaging
Male
Temporal Lobe/diagnostic imaging
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1702
[Cu] Class update date: 170227
[Lr] Last revision date:170227
[Js] Journal subset:IM
[Da] Date of entry for processing:160827
[St] Status:MEDLINE

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[PMID]: 27368507
[Au] Autor:Ben Nsir A; Hadhri R; Kilani M; Chabaane M; Darmoul M; Hattab N
[Ad] Address:Department of Neurosurgery, Fattouma Bourguiba University Hospital, The University of Medicine of Monastir, Monastir, Tunisia. Electronic address: atefbn@hotmail.fr.
[Ti] Title:Epidural Venous Angioma Presenting with Spinal Cord Compression in a 42-Year-Old Woman with Previous History of Ovarian Malignancy.
[So] Source:World Neurosurg;93:488.e5-7, 2016 Sep.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Venous angioma is an extremely rare vascular malformation of the epidural space. To the best of our knowledge, only 5 cases have been documented to date and none has been reported in the setting of a previous malignancy. CASE DESCRIPTION: We report the case of a 42-year-old woman with a previous history of ovarian cancer, treated by surgery plus chemotherapy; who presented with signs of spinal cord compression for 3 weeks. Magnetic resonance imaging showed an intensely enhancing epidural mass at the T2-T6 level causing major spinal cord compression, for which urgent surgery was indicated. During surgery, the tumor was extremely hemorrhagic and the hemostasis was hazardous. Blood loss was estimated at 1.5 L, causing hemodynamic instability and requiring intensive resuscitation with fluids and blood transfusions. Gross total resection was achieved and the pathologic examination confirmed the diagnosis of venous angioma. The patient recovered quickly postoperatively and was able to walk independently within 2 weeks of starting intensive rehabilitation. She was symptom free with no clinical or radiologic evidence of recurrence at 1 year follow-up. CONCLUSIONS: Venous angioma should be included in the differential diagnosis of spinal epidural masses even in case of previous malignancy. Subtle imaging features should alert clinicians to this rare yet potentially life-threatening condition. Surgery remains the cornerstone of the treatment and can result in remarkable recovery.
[Mh] MeSH terms primary: Central Nervous System Venous Angioma/surgery
Epidural Neoplasms/secondary
Epidural Neoplasms/surgery
Ovarian Neoplasms/pathology
Ovarian Neoplasms/surgery
Spinal Cord Compression/prevention & control
[Mh] MeSH terms secundary: Central Nervous System Venous Angioma/complications
Central Nervous System Venous Angioma/pathology
Diagnosis, Differential
Epidural Neoplasms/pathology
Female
Humans
Middle Aged
Spinal Cord Compression/diagnostic imaging
Spinal Cord Compression/etiology
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1709
[Cu] Class update date: 170906
[Lr] Last revision date:170906
[Js] Journal subset:IM
[Da] Date of entry for processing:160703
[St] Status:MEDLINE

  10 / 223 MEDLINE  
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[PMID]: 27333758
[Au] Autor:Nakase H; Motoyama Y; Yamada S
[Ti] Title:[Cerebral hemorrhage].
[So] Source:Nihon Rinsho;74(4):671-6, 2016 Apr.
[Is] ISSN:0047-1852
[Cp] Country of publication:Japan
[La] Language:jpn
[Ab] Abstract:Intracerebral hemorrhage (ICH) remains a serious condition for which early aggressive care is warranted. Japanese evidence-based stroke guidelines were published in 2015 to present the current and comprehensive recommendations for the diagnosis and treatment of stroke. In the spontaneous ICH, topics focused on prevention, management in the acute and chronic stage, complications, management of coagulopathy and blood pressure, prevention and control of secondary brain injury and intracranial pressure, the role of surgery, and other pathologies of ICH. The management of ICH in pregnancy and the puerperium was newly added. These guidelines provide a framework for goal-directed treatment of the patient with ICH.
[Mh] MeSH terms primary: Cerebral Hemorrhage/etiology
Cerebral Hemorrhage/therapy
Practice Guidelines as Topic
[Mh] MeSH terms secundary: Acute Disease
Antihypertensive Agents/administration & dosage
Brain Neoplasms/complications
Central Nervous System Vascular Malformations/complications
Cerebral Hemorrhage/prevention & control
Factor VIIa/administration & dosage
Female
Hemangioma, Cavernous/complications
Humans
Hypertension/complications
Hypertension/drug therapy
Intracranial Arteriovenous Malformations/complications
Male
Minimally Invasive Surgical Procedures
Neurosurgical Procedures
Platelet Aggregation Inhibitors/adverse effects
Pregnancy
Pregnancy Complications
Pulmonary Embolism/prevention & control
Recombinant Proteins/administration & dosage
Recurrence
Respiration, Artificial
Venous Thrombosis/prevention & control
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Nm] Name of substance:0 (Antihypertensive Agents); 0 (Platelet Aggregation Inhibitors); 0 (Recombinant Proteins); AC71R787OV (recombinant FVIIa); EC 3.4.21.21 (Factor VIIa)
[Em] Entry month:1607
[Cu] Class update date: 161126
[Lr] Last revision date:161126
[Js] Journal subset:IM
[Da] Date of entry for processing:160624
[St] Status:MEDLINE


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