Database : MEDLINE
Search on : cerebral and hemorrhage [Words]
References found : 66666 [refine]
Displaying: 1 .. 10   in format [Detailed]

page 1 of 6667 go to page                         

  1 / 66666 MEDLINE  
              next record last record
select
to print
Photocopy
Full text

[PMID]: 29099394
[Au] Autor:Ninomiya K; Fukasawa M; Kawakami Y; Fuke C; Miyazaki T
[Ad] Address:From the Department of Legal Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
[Ti] Title:Nontraumatic Convexal Subarachnoid Hemorrhage Accompanied by Sylvian Hematoma: An Autopsy Case of Ruptured Distal Middle Cerebral Artery Aneurysm.
[So] Source:Am J Forensic Med Pathol;, 2017 Nov 02.
[Is] ISSN:1533-404X
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:We describe an autopsy case of nontraumatic convexal subarachnoid hemorrhage (cSAH) accompanied by sylvian hematoma. A woman in her 50s was found dead in her house. On autopsy, massive cSAH accompanied by sylvian hematoma was observed. Because of the absence of subarachnoid hemorrhage (SAH) in the basal cistern, initial suspicion was that of a traumatic SAH. After a detailed investigation, a ruptured cerebral aneurysm of the distal middle cerebral artery was found in the hematoma, and the cSAH in this case was confirmed to be endogenous. Convexal subarachnoid hemorrhages typically result from traumatic injury, whereas endogenous cSAHs are exceedingly rare. Autopsy findings of a sylvian hematoma with SAH may result from endogenous hemorrhage from ruptured aneurysm of the distal middle cerebral artery. Detailed investigation of the hematoma may help identify the culprit lesion and help arrive at the correct postmortem diagnosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.1097/PAF.0000000000000353

  2 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29099302
[Au] Autor:Skodvin TØ; Evju Ø; Helland CA; Isaksen JG
[Ad] Address:Faculty of Health, UiT The Arctic University of Norway, Tromsø.
[Ti] Title:Rupture prediction of intracranial aneurysms: a nationwide matched case-control study of hemodynamics at the time of diagnosis.
[So] Source:J Neurosurg;:1-7, 2017 Nov 03.
[Is] ISSN:1933-0693
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE Hemodynamic rupture predictors in intracranial aneurysms (IAs) must be investigated in prerupture aneurysms, because rupture might significantly alter aneurysm hemodynamics. Both clinical and aneurysmal factors influence hemodynamics, possibly confounding results in unmatched patient materials. The authors aimed to identify hemodynamic variables at the time of diagnosis that could be associated with IA rupture. METHODS A nationwide matched case-control study of IA hemodynamics at the time of diagnosis was performed. Twelve IAs that later ruptured were matched 1:2 with control aneurysms that remained unruptured during a median follow-up time of 4.5 years (interquartile range 3.7-8.2 years). Cases and controls were matched by aneurysm location and size, and patient sex and age. Hemodynamic parameters were obtained from computational fluid dynamics simulations. RESULTS The low shear area (LSA) was significantly higher in cases than in controls in univariate analysis (p = 0.041). Minimum logarithmic wall shear stress, averaged logarithmic wall shear stress, pressure loss coefficient, and inflow concentration index showed a tendency to be associated with later rupture (p = 0.09, 0.14, 0.15, and 0.18, respectively). The LSA remained statistically significant in multivariable analysis (p = 0.030). CONCLUSIONS Hemodynamics at the time of diagnosis are different in aneurysms that later rupture than in those that remain unruptured. Increased LSA might be an early predictor of rupture.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.3171/2017.5.JNS17195

  3 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29099296
[Au] Autor:Nagahama Y; Allan L; Nakagawa D; Zanaty M; Starke RM; Chalouhi N; Jabbour P; Brown RD; Derdeyn CP; Leira EC; Broderick J; Chimowitz M; Torner JC; Hasan D
[Ad] Address:Departments of 1 Neurosurgery and.
[Ti] Title:Dual antiplatelet therapy in aneurysmal subarachnoid hemorrhage: association with reduced risk of clinical vasospasm and delayed cerebral ischemia.
[So] Source:J Neurosurg;:1-9, 2017 Nov 03.
[Is] ISSN:1933-0693
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:OBJECTIVE Clinical vasospasm and delayed cerebral ischemia (DCI) are devastating complications of aneurysmal subarachnoid hemorrhage (aSAH). Several theories involving platelet activation have been postulated as potential explanations of the development of clinical vasospasm and DCI. However, the effects of dual antiplatelet therapy (DAPT; aspirin and clopidogrel) on clinical vasospasm and DCI have not been previously investigated. The objective of this study was to evaluate the effects of DAPT on clinical vasospasm and DCI in aSAH patients. METHODS Analysis of patients treated for aSAH during the period from July 2009 to April 2014 was performed in a single-institution retrospective study. Patients were divided into 2 groups: patients who underwent stent-assisted coiling or placement of flow diverters requiring DAPT (DAPT group) and patients who underwent coiling only without DAPT (control group). The frequency of symptomatic clinical vasospasm and DCI and of hemorrhagic complications was compared between the 2 groups, utilizing univariate and multivariate logistic regression. RESULTS Of 312 aSAH patients considered for this study, 161 met the criteria for inclusion and were included in the analysis (85 patients in the DAPT group and 76 patients in the control group). The risks of clinical vasospasm (OR 0.244, CI 95% 0.097-0.615, p = 0.003) and DCI (OR 0.056, CI 95% 0.01-0.318, p = 0.001) were significantly lower in patients receiving DAPT. The rates of hemorrhagic complications associated with placement of external ventricular drains and ventriculoperitoneal shunts were similar in both groups (4% vs 2%, p = 0.9). CONCLUSIONS The use of DAPT was associated with a lower risk of clinical vasospasm and DCI in patients treated for aSAH, without an increased risk of hemorrhagic complications.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher
[do] DOI:10.3171/2017.5.JNS17831

  4 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29097336
[Au] Autor:Liu W; Li C; Liu X; Xu Z; Kong L
[Ad] Address:Department of Neurosurgery, Affiliated hospital of Qingdao University.
[Ti] Title:A Case of Subarachnoid Hemorrhage Caused by Tuberculous Aneurysm.
[So] Source:World Neurosurg;, 2017 Oct 30.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In this paper, we report a case of intracranial tuberculum with adjacent intracerebral inflammatory aneurysm, and include a brief discussion of the developmental mechanism of these pathologies. A 28-year-old man presented with sudden onset of severe headache. He was diagnosed with h pulmonary tuberculosis 8 year ago, and had been treated with anti-tuberculosis medications for 6 months. Head computed tomography (CT) showed a small hematoma in the left Sylvian fissure with subarachnoid hemorrhage. Cerebral digital subtraction angiograph (DSA) was performed and no aneurysm was found. He was discharged after non-surgical treatment. Three weeks later, he came back to our department with complaint of aphasia. Magnetic resonance (MR) images showed a cystic lesion with mass effect. During operation, we encounter the brain abscess and were surprised to find a middle cerebral artery aneurysm while dissecting. The abscess was totally removed, and the aneurysm was secured by clipping. The aneurysm was suspected of being inflammatory in nature and associated with the patient's tuberculosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher

  5 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29097330
[Au] Autor:Turan N; Miller BA; Huie JR; Heider RA; Wang J; Wali B; Yousuf S; Ferguson AR; Sayeed I; Stein DG; Pradilla G
[Ad] Address:Emory University School of Medicine, Department of Neurosurgery, Atlanta, GA, USA; Cerebrovascular Research Laboratory, Department of Neurosurgery, Atlanta, GA, USA.
[Ti] Title:Effect of Progesterone on Cerebral Vasospasm and Neurobehavioral Outcomes In A Rodent Model of Subarachnoid Hemorrhage.
[So] Source:World Neurosurg;, 2017 Oct 30.
[Is] ISSN:1878-8769
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: Subarachnoid hemorrhage (SAH) induces widespread inflammation leading to cellular injury, vasospasm and ischemia. Evidence suggests that progesterone (PROG) can improve functional recovery in acute brain injury due to its anti-inflammatory and neuroprotective properties, which could also be beneficial in SAH. We hypothesized that PROG treatment attenuates inflammation mediated cerebral vasospasm and microglial activation, improves synaptic connectivity, and ameliorates functional recovery after SAH. METHODS: We investigated the effect of PROG in a cisternal SAH model in adult male C57BL/6 mice. Neurobehavioral outcomes were evaluated using rotarod latency, open field activity and grip strength tests. Basilar artery perimeter, AMPA-GluR1/synaptophysin colocalization and Iba-1 immunoreactivity were quantified histologically. RESULTS: PROG (8 mg/kg) significantly improved rotarod latency at day 6 and grip strength at day 9. PROG treated animals had significantly reduced basilar artery vasospasm at 24h. Colocalization of GluR1/synaptophysin, indicative of synaptic GluR1, was significantly reduced in the SAH+Vehicle group at 24 h, and PROG treatment significantly attenuated this reduction. PROG treatment significantly reduced microglial cell activation and proliferation in cerebellum and cortex, but not in the brainstem at 10 days. CONCLUSIONS: PROG treatment ameliorated cerebral vasospasm, reduced microglial activation, restored synaptic GluR1 localization and improved neurobehavioral performance in a murine model of SAH. These results provide a rationale for further translational testing of PROG therapy in SAH.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher

  6 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29096139
[Au] Autor:Reinacher PC; Coenen VA; Kraeutle R; Scheiwe C; Jabbarli R; Roelz R
[Ad] Address:Department of Stereotactic and Functional Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany.
[Ti] Title:Feasibility of stereotactic catheter ventriculocisternostomy for cisternal lavage therapy in patients with subarachnoid hemorrhage.
[So] Source:Clin Neurol Neurosurg;163:94-102, 2017 Oct 16.
[Is] ISSN:1872-6968
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Delayed cerebral infarction (DCI) confers considerable morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH). Available prevention strategies are insufficient. Cisternal blood clearance by stereotactic catheter ventriculocisternostomy (STX-VCS) and cisternal lavage therapy is a novel concept for DCI prevention. Here, we assess the general feasibility, pitfalls and imaging requirements of STX-VCS after aSAH. PATIENTS AND METHODS: 73 aSAH patients admitted between 2008 and 2015 with appropriate imaging for simulation of stereotactic procedures were included. Surgical feasibility of a transventricular trajectory to the basal cisterns was assessed. RESULTS: Transventricular catheter access to the basal cisterns was feasible in 94% of cases. In 6% vascular obstacles precluded a transventricular approach and access to the basal cisterns could be simulated via a transparenchymal trajectory. CT-artifacts that interfered with stereotactic planning were observed in 58% after coiling and 5% after clipping. In these cases stereotactic planning was enabled by MRI. Logistic regression of aneurysm size and distance-to-target allowed for precise prediction whether MRI was required for stereotactic planning of STX-VCS after coiling. CONCLUSIONS: Stereotactic catheter access to the basal cisterns after aSAH appears to be generally feasible. Coil artifacts compromising CT-based planning can be precisely anticipated and planning enabled by MRI.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[St] Status:Publisher

  7 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29095842
[Au] Autor:Park JH; Kim CS; Won KS; Oh JS; Kim JS; Kim HW
[Ad] Address:Department of Pediatrics, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
[Ti] Title:Asymmetry of cerebral glucose metabolism in very low-birth-weight infants without structural abnormalities.
[So] Source:PLoS One;12(11):e0186976, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:METHODS: Thirty-six VLBW infants who underwent F-18 fluorodeoxyglucose (F-18 FDG) brain PET and MRI were prospectively enrolled, while infants with evidence of parenchymal brain injury on MRI were excluded. The regional glucose metabolic ratio and asymmetry index were calculated. The asymmetry index more than 10% (right > left asymmetry) or less than -10% (left > right asymmetry) were defined as abnormal. Regional cerebral glucose metabolism were compared between right and left cerebral hemispheres, and between the following subgroups: multiple gestations, premature rupture of membrane, bronchopulmonary dysplasia, and low-grade intraventricular hemorrhage. RESULTS: In the individual analysis, 21 (58.3%) of 36 VLBW infants exhibited asymmetric cerebral glucose metabolism. Fifteen infants (41.7%) exhibited right > left asymmetry, while six (16.7%) exhibited left > right asymmetry. In the regional analysis, right > left asymmetry was more extensive than left > right asymmetry. The metabolic ratio in the right frontal, temporal, and occipital cortices and right thalamus were significantly higher than those in the corresponding left regions. In the subgroup analyses, the cerebral glucose metabolism in infants with multiple gestations, premature rupture of membrane, bronchopulmonary dysplasia, or low-grade intraventricular hemorrhage were significantly lower than those in infants without these. CONCLUSION: VLBW infants without structural abnormalities have asymmetry of cerebral glucose metabolism. Decreased cerebral glucose metabolism are noted in infants with neurodevelopmental risk factors. F-18 FDG PET could show microstructural abnormalities not detected by MRI in VLBW infants.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[St] Status:In-Process
[do] DOI:10.1371/journal.pone.0186976

  8 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29076900
[Au] Autor:Schmidt MQ; Schraml FV
[Ad] Address:From the *Creighton University School of Medicine; and †Department of Radiology, St. Joseph's Hospital and Medical Center, Phoenix, AZ.
[Ti] Title:Absent Cerebellar Circulation With Intact Cerebral Blood Flow on a 99mTc Bicisate "Brain Death" Study.
[So] Source:Clin Nucl Med;42(12):983-984, 2017 Dec.
[Is] ISSN:1536-0229
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:A 55-year old woman presented in an obtunded state and was found to have a subarachnoid hemorrhage. After endovascular repair, her condition deteriorated, and brain death was suspected. A Tc bicisate brain blood flow study was performed, which showed a complete absence of blood flow to the cerebellum despite intact circulation to the cerebral hemispheres. These atypical findings are likely a result of a transient intracranial pressure differential and the timing of the study. A timely and accurate declaration of brain death has important psychosocial and ethical implications, particularly when organ donation is being considered.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:In-Process
[do] DOI:10.1097/RLU.0000000000001866

  9 / 66666 MEDLINE  
              first record previous record next record last record
select
to print
Photocopy
Full text

[PMID]: 29069046
[Au] Autor:Cai Q; Zhang H; Zhao D; Yang Z; Hu K; Wang L; Zhang W; Chen Z; Chen Q
[Ad] Address:aDepartment of Neurosurgery, Renmin Hospital of Wuhan University, Hubei Province bDepartments of Neurosurgery, PLA General Hospital, Beijing cDepartments of Neurosurgery, the Second Clinical Medical College, Yangtze University, Hubei Province dDepartment of Radiology, Renmin Hospital of Wuhan University, Hubei province eDepartment of Neurosurgery, Central Hospital of Xiangyang City, Hubei Province, China.
[Ti] Title:Analysis of three surgical treatments for spontaneous supratentorial intracerebral hemorrhage.
[So] Source:Medicine (Baltimore);96(43):e8435, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:This retrospective study aimed to evaluate the effectiveness and safety of 3 surgical procedures for Spontaneous Supratentorial Intracerebral Hemorrhage (SICH).A total of 63 patients with SICH were randomized into 3 groups. Group A (n = 21) underwent craniotomy surgery, group B (n = 22) underwent burr hole, urokinase infusion and catheter drainage, and group C (n = 20) underwent neuroendoscopic surgery. The hematoma evacuation rate of the operation was analyzed by 3D Slice software and the average surgery time, visualization during operation, decompressive effect, mortality, Glasgow Coma Scale (GCS) improvement, complications include rebleeding, pneumonia, intracranial infection were also compared among 3 groups.All procedures were successfully completed and the hematoma evacuation rate was significant differences among 3 groups which were 79.8%, 43.1%, 89.3% respectively (P < .01), and group C was the highest group. Group B was smallest traumatic one and shared the shortest operation time, but for the lack of hemostasis, it also the highest rebleeding group (P = .03). Although there were different in complications, but there was no significant in pneumonia, intracranial infection, GCS improvement and mortality rate.All these 3 methods had its own advantages and shortcomings, and every approach had its indications for SICH. Although for neuroendoscopic technical's minimal invasive, direct vision, effectively hematoma evacuation rate, and the relatively optimistic result, it might be a more promising approach for SICH.
[Mh] MeSH terms primary: Cerebral Hemorrhage/surgery
Craniotomy/methods
Drainage/methods
Hematoma/surgery
Neuroendoscopy/methods
[Mh] MeSH terms secundary: Adult
Aged
Cerebral Hemorrhage/mortality
Craniotomy/adverse effects
Drainage/adverse effects
Female
Glasgow Coma Scale
Hematoma/mortality
Humans
Male
Middle Aged
Neuroendoscopy/adverse effects
Operative Time
Random Allocation
Retrospective Studies
Treatment Outcome
[Pt] Publication type:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:171025
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008435

  10 / 66666 MEDLINE  
              first record previous record
select
to print
Photocopy
Full text

[PMID]: 29061392
[Au] Autor:Wei Y; Deng X; Sheng G; Guo XB
[Ad] Address:Department of Neuro-Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, 450052, China.
[Ti] Title:A rabbit model of cerebral venous sinus thrombosis established by ferric chloride and thrombin injection.
[So] Source:Neurosci Lett;662:205-212, 2017 Oct 20.
[Is] ISSN:1872-7972
[Cp] Country of publication:Ireland
[La] Language:eng
[Ab] Abstract:OBJECTIVE: Cerebral venous sinus thrombosis (CVST) is a life-threatening disease with high misdiagnosis and mortality rates due to its complex etiology and unknown pathophysiology. The present study aimed to establish an animal model suitable for assessing the pathophysiology of CVST and develop treatment methods. METHODS: 40% ferric chloride (FeCl3) was administered for 5min followed by thrombin injection to induce superior sagittal sinus thrombosis (SSST). Digital subtraction angiography (DSA) was performed to ensure thrombosis and evaluate the recanalization rate 7days post-CVST. Neurological evaluation, Evans blue injection, 2,3,5-Triphenyltetrazolium chloride (TTC), and hematoxylin-eosin (H&E) staining were used to assess thrombosis and the accompanying brain parenchyma. RESULTS: SSST was detected in all model rabbits, with a thrombus recanalization rate of 10%. Brain infarction, hemorrhage, cell edema, and disruption of the blood-brain barrier (BBB) were also observed. CONCLUSION: The method of inducing cerebral venous sinus thrombosis by applying 40% FeCl3 and injecting thrombin is feasible and efficient. This experimental model mimics the pathogenesis and pathophysiology of actual CVST.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher


page 1 of 6667 go to page                         
   


Refine the search
  Database : MEDLINE Advanced form   

    Search in field  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/PAHO/WHO - Latin American and Caribbean Center on Health Sciences Information