Database : MEDLINE
Search on : cheilitis [Words]
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  1 / 2195 MEDLINE  
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[PMID]: 29512976
[Au] Autor:Brumana MB; Marinello E; Piaserico S; Linder MD; Cozzani E; Zattra E; Belloni Fortina A
[Ad] Address:Humanitas San Pio X, Milan, Italy.
[Ti] Title:Herpes simplex reactivation after photodynamic therapy for actinic cheilitis in a patient with Non-Hodgkin Lymphoma: a possible indication for prophylaxis.
[So] Source:G Ital Dermatol Venereol;, 2018 Mar 06.
[Is] ISSN:1827-1820
[Cp] Country of publication:Italy
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180307
[Lr] Last revision date:180307
[St] Status:Publisher
[do] DOI:10.23736/S0392-0488.18.05824-8

  2 / 2195 MEDLINE  
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[PMID]: 29505701
[Au] Autor:Carrard VC; Roxo Gonçalves M; Strey JR; Pilz C; Martins MAT; Martins MD; Schmitz CA; Dal Moro RG; D'Ávila OP; Rados DRV; Harzheim E; Gonçalves MR
[Ad] Address:Oral Pathology Department, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
[Ti] Title:Telediagnosis of oral lesions in primary care: the EstomatoNet Program.
[So] Source:Oral Dis;, 2018 Mar 05.
[Is] ISSN:1601-0825
[Cp] Country of publication:Denmark
[La] Language:eng
[Ab] Abstract:OBJECTIVE: The diagnosis of oral lesions are often challenging for primary health care providers, which explains the high number of referrals to specialist care. This favors increases in waiting lines and delays in diagnosis, contributing to high mortality rates from oral cancer. This study aimed to summarize the experience of the EstomatoNet, a telediagnosis program catering to primary care dentists and physicians from southern Brazil. STUDY DESIGN: This exploratory study included all queries received by EstomatoNet from June/2015 to December/2016. Health providers (71 dentists and 18 physicians from primary care) submitted requests including clinical information and photographs of oral lesions by means of a cloud-based platform. Specialized oral medicine teleconsultants received the data, conveyed a diagnostic hypothesis, and management recommendations. RESULTS: Actinic cheilitis (n=41, 15.8%), squamous cell carcinoma (n=22, 8.5%), and inflammatory hyperplasia (21, 8.1%) were the most frequent diagnoses. Teleconsultants recommended referral to specialists in 42.9% of the cases, total biopsy in 23.6%, and follow-up in 16.2%. After the EstomatoNet use the intention to refer the patients to face-to-face consultation reduced from 96.9% to 35.1%. CONCLUSION: Telediagnosis for oral lesions is feasible and has potential to improve the quality primary health care by bridging the gap between primary and specialized healthcare. This article is protected by copyright. All rights reserved.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180305
[Lr] Last revision date:180305
[St] Status:Publisher
[do] DOI:10.1111/odi.12851

  3 / 2195 MEDLINE  
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[PMID]: 29464980
[Au] Autor:Mansouri P; Azizian Z; Hejazi S; Chalangari R; Chalangari KM
[Ad] Address:a Skin and Stem Cell Research Center, Tehran University of Medical Sciences , Tehran , Iran.
[Ti] Title:Evaluation the efficacy of trichloroacetic acid (TCA) 33% in treatment of oral retinoid-induced cheilitis compared with placebo (Vaseline): a randomized pilot study.
[So] Source:J Dermatolog Treat;:1-4, 2018 Mar 06.
[Is] ISSN:1471-1753
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Oral Isotretinoin (13-cis-retinoic acid) is a gold standardtreatment for severe forms of acne with cheilitis as a most frequent complication. We designed this novel study to investigate the therapeutic effect of trichloroacetic acid (TCA) 33% as compared with placebo to treat cheilitis. METHODS: In this pilot study, 90 acne vulgaris patients between 18 and 50 years, who referred dermatologic clinic with cheilitis, were assigned to either case (TCA) or control (Vaseline) group using permuted-block randomization from 2013 to 2015 with data analysis in 2016. Patients had follow-up visits after 2 and 6 weeks, at which their lesions were photographed. Two blinded expert dermatologists recorded physician International global score for each image. RESULTS: Ninety eligible patients were randomly allocated into two groups. This included 45 patients in each group. At the end of follow-up, 44 patients in the intervention group and 37 patients in control group completed the final assessment. Compared to the control group, the TCA group had a greater reduction in the mean ICGS value from baseline to Week 6 (mean difference 2.59 points, p < .0001). CONCLUSIONS: TCA can be considered as a good strategy in improvement of cheilitis to isotretinoin therapy.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180306
[Lr] Last revision date:180306
[St] Status:Publisher
[do] DOI:10.1080/09546634.2018.1441489

  4 / 2195 MEDLINE  
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[PMID]: 29476334
[Au] Autor:Aragón F; Zea-Sevilla MA; Montero J; Sancho P; Corral R; Tejedor C; Frades-Payo B; Paredes-Gallardo V; Albaladejo A
[Ad] Address:Department of Surgery, Faculty of Medicine and Dentistry, University of Salamanca, Campus Miguel de Unamuno, Calle Alfonso X El Sabio s/n, 37007, Salamanca, Spain. fernan_z14z@hotmail.com.
[Ti] Title:Oral health in Alzheimer's disease: a multicenter case-control study.
[So] Source:Clin Oral Investig;, 2018 Feb 23.
[Is] ISSN:1436-3771
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:OBJECTIVES: The aim of this case-control study was to carry out an oral health assessment on a group of Alzheimer's patients and to establish a hypothesis regarding the implication of the characteristics of the disease and the treatment of oral health. MATERIALS AND METHODS: A total of 70 Alzheimer's patients, residents at the Alzheimer Center Reina Sofia Foundation (Madrid, Spain) and at the Alzheimer State Reference Center (Salamanca, Spain), and 36 controls (companions/acquaintances), were studied by oral examination and saliva sampling. The oral health indices DMFT/DMFS, CPI, the prosthetic condition, oral hygiene, saliva volume, and pH, as well as the specific microbiological parameters governing the risk of developing caries were assessed. RESULTS: Alzheimer's patients exhibited, as compared to the control group, (1) fewer teeth (10.9 ± 10.5 vs 23.7 ± 6.5), (2) fewer obturations (2.2 ± 3.4 vs 6.6 ± 5.6), (3) fewer periodontally healthy sextants (0.1 ± 0.4 vs 1.4 ± 2.2), (4) worse oral hygiene (43.1 vs 72.2% brushed), (5) greater use of removable prostheses (47.8 vs 8.4%), (6) higher incidence of candida infection (11.8 vs 0.0%) and cheilitis (15.9 vs 0.0%), (7) lower salivary flow (0.6 ± 0.6 vs 1.1 ± 0.6), and (8) lower buffering capacity (46 vs 80%). CONCLUSIONS: After taking into account the influence of age, Alzheimer's patients had worse oral health (caries and periodontal disease), more mucosal lesions (cheilitis and candidiasis), and worse saliva quantity and quality. CLINICAL RELEVANCE: Clinicians should be aware of the implications of Alzheimer's disease in oral health, in order to stablish the effective preventive measures and the optimal treatment plan.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180224
[Lr] Last revision date:180224
[St] Status:Publisher
[do] DOI:10.1007/s00784-018-2396-z

  5 / 2195 MEDLINE  
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[PMID]: 29460518
[Au] Autor:Ottria L; Lauritano D; Oberti L; Candotto V; Cura F; Tagliabue A; Tettamanti L
[Ad] Address:Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
[Ti] Title:Prevalence of HIV-related oral manifestations and their association with HAART and CD4+ T cell count: a review.
[So] Source:J Biol Regul Homeost Agents;32(2 Suppl. 1):51-59, 2018 Jan-Feb.
[Is] ISSN:0393-974X
[Cp] Country of publication:Italy
[La] Language:eng
[Ab] Abstract:HIV infection is one of the major health problem of the last decades. This disease causes a chronic infection that can lead to acquired immunodeficiency syndrome (AIDS). According to the Global AIDS update, released in 2016 by HIV department of World Health Organization (WHO) and by the Joint United Nations Program on HIV/AIDS (UNAIDS), at the end of 2015, 36.7 million people were infected by HIV: 34.9 million of these were adults and 1.8 million were children under 15 years of age. The same report shows that during 2015, 2.1 million of new infection cases have occurred all over the world and about 1.1 million people have died for HIV. The aim of this short review is to up-date of the main HIV-related oral manifestations and their correlation with HAART (Highly Active Antiretroviral Therapy) and CD4+ T-cell count. Despite that more than 20 years have elapsed, this classification still remains valid: even today, group 1 lesions are found in the majority of HIV-positive patients with oral manifestations. Group 1 includes the following conditions: oral candidiasis (pseudomembranous candidiasis, erythematous candidiasis, angle cheilitis), oral hairy leukoplakia, periodontal diseases (necrotizing gingivitis, necrotizing periodontitis, linear gingival erythema), Kaposi’s sarcoma, and non-Hodgkin’s lymphoma. Melanotic hyperpigmentation, HSV infection and HPV infection, which are included in group 2, are also common. Oral candidiasis, oral hairy leukoplakia, Kaposi’s sarcoma and HSV infection are the lesions that have seen the major drop in their incidence after the HAART introduction. The increase in CD4+ T-cell count is not significantly correlated to the decrease of every type of oral lesions, but it is statistically significant only in relation to oral candidiasis (p-value less than 0.001). Oral lesions are an important sign of immunodepression and with the introduction of HAART their incidence has strongly decreased, particularly in urban areas. Nevertheless, developing countries still have a high prevalence of these manifestations because of the persistence of many risk factors, like the difficulty to access treatment, poor oral hygiene, low socioeconomic status and late diagnosis.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180220
[Lr] Last revision date:180220
[St] Status:In-Data-Review

  6 / 2195 MEDLINE  
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[PMID]: 29457989
[Au] Autor:Aoki Y; Kitazawa K; Kobayashi H
[Ad] Address:a Department of Pediatrics , Asahi General Hospital , Chiba , Japan.
[Ti] Title:Propylthiouracil-induced anti-neutrophil cytoplasmic antibody-associated vasculitis mimicking Kawasaki disease.
[So] Source:Paediatr Int Child Health;:1-4, 2018 Feb 19.
[Is] ISSN:2046-9055
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is rare in children and is characterised as necrotising vasculitis predominantly affecting small and medium-sized vessels. Propylthiouracil (PTU), an antithyroid drug, has been implicated in drug-induced AAV. In contrast, Kawasaki disease (KD) is a common systemic vasculitis, typically observed in children, which affects the medium-sized vessels, including the coronary arteries. An 11-year-old girl who developed AAV while receiving PTU therapy for Graves' disease is described. She was admitted to hospital following a 2-day history of fever, cervical adenopathy, cheilitis and papular rash, 3 weeks after an increase in the PTU dose. Despite discontinuation of PTU and the administration of intravenous antibiotic therapy, her clinical condition deteriorated and over the next 2 days she developed severe diarrhoea, conjunctival injection and swelling and redness of the right index finger. Additional findings included liver dysfunction, hydrops of the gallbladder, coagulopathy and urine abnormalities, suggesting glomerulonephritis. She met the diagnostic criteria for KD and received intravenous immunoglobulin (IVIG) combined with prednisolone, with rapid resolution of clinical and laboratory parameters. Peeling of the right index fingertip became evident on Day 12 of admission. Serial ultrasound cardiography demonstrated no evidence of cardiac involvement. A high titre of myeloperoxidase ANCA was detected in the patient's serum on admission, and the titre decreased during the convalescent stage. This case demonstrates that children with PTU-associated AAV may present with clinical features mimicking KD, and that IVIG along with corticosteroid therapy may be effective in treating patients with drug-induced severe systemic AAV.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180219
[Lr] Last revision date:180219
[St] Status:Publisher
[do] DOI:10.1080/20469047.2018.1435173

  7 / 2195 MEDLINE  
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[PMID]: 29446120
[Au] Autor:Forward E; Harris V; Smith SD
[Ad] Address:Department of Dermatology, Royal North Shore Hospital, St Leonards, 2065 New South Wales, Australia.
[Ti] Title:A novel case of a brush with discomfort: allergic contact dermatitis caused by mercaptobenzothiazole in rubber components of a toothbrush.
[So] Source:Contact Dermatitis;, 2018 Feb 15.
[Is] ISSN:1600-0536
[Cp] Country of publication:England
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180215
[Lr] Last revision date:180215
[St] Status:Publisher
[do] DOI:10.1111/cod.12967

  8 / 2195 MEDLINE  
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[PMID]: 29426753
[Au] Autor:Nettis E; Di Leo E; Bisaccia M; Marasco C; Foti C; Vacca A
[Ad] Address:Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine "G. Baccelli", "Aldo Moro" University of Bari Medical School, Policlinico, Bari, Italy.
[Ti] Title:A favorable response to omalizumab in a patient with cheilitis granulomatosa.
[So] Source:J Allergy Clin Immunol Pract;, 2018 Feb 06.
[Is] ISSN:2213-2201
[Cp] Country of publication:United States
[La] Language:eng
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180210
[Lr] Last revision date:180210
[St] Status:Publisher

  9 / 2195 MEDLINE  
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[PMID]: 29422459
[Au] Autor:Talattof Z; Azad A; Zahed M; Shahradnia N
[Ad] Address:Department of Oral and Maxillofacial Medicine, School of Dentistry, Islamic Azad University of Medical Sciences, Shiraz Islamic Republic of Iran.
[Ti] Title:Antifungal Activity of Xylitol against Candida albicans: An in vitro Study.
[So] Source:J Contemp Dent Pract;19(2):125-129, 2018 Feb 01.
[Is] ISSN:1526-3711
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:AIM: The most common fungal infection among human population is candidiasis, the etiology of which is mostly Candida albicans. As a result of a disrupted balance of the normal flora or a compromised immune system, Candida species can become pathogenic. Various in vitro surveys have shown that glucose intake is a promoter of C. albicans growth, whereas in vivo studies have found that xylitol can decrease the risk of candidiasis and angular cheilitis. Hence, we aimed to evaluate for the first time the inhibitory effects of xylitol on C. albicans by assessing its minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). MATERIALS AND METHODS: The standard strain of C. albicans was acquired. The fungi were incubated in supplemented brain-heart infusion broth for 48 hours at 37°C. The MIC was measured according to the Clinical and Laboratory Standards Institute (CLSI) M100-S24 standard. Microdilution method was applied using 360-uL sterilized polystyrene flat-bottomed 96-well plates. The antimicrobial effects were examined by the microbroth dilution method according to the CLSI M100-S24 standard. RESULTS: The MIC of xylitol for C. albicans was found to be 20 × 10 µg/mL. Furthermore, the concentration of 40 × 10 µg/mL with a decrease of 99.95% in the colony-forming units (CFUs) of the microorganism was found to be the MFC of xylitol for C. albicans. CONCLUSION: According to the results of this survey, xylitol has considerable antimicrobial effects. Hence, this substance can be used as an effective element in gums, toothpastes, and antimicrobial mouthwashes, especially in patients with candidiasis. CLINICAL SIGNIFICANCE: By knowing the MIC and MFC of xylitol, this substance can be effectively used in products aimed to cure this fungal infection.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180209
[Lr] Last revision date:180209
[St] Status:In-Process

  10 / 2195 MEDLINE  
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[PMID]: 29281699
[Au] Autor:Kim M; Yoo J; Kim J; Park J; Han E; Jang W; Chae H; Lee JH; Park YM; Kim Y
[Ad] Address:Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
[Ti] Title:Association of FLG single nucleotide variations with clinical phenotypes of atopic dermatitis.
[So] Source:PLoS One;12(12):e0190077, 2017.
[Is] ISSN:1932-6203
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:BACKGROUND: FLG encodes a large protein called profilaggrin, which plays a key role in maintaining an effective skin barrier against the environment. In this study, we identified FLG single nucleotide variations (FLG-SNVs) and evaluated the association of FLG-SNVs with clinical phenotypes including atopic dermatitis (AD)-associated minor clinical features, presence of specific allergic sensitization, and serum parameters. METHODS: Eighty-one Korean patients with AD were enrolled. AD-associated minor clinical features as well as allergic rhinitis and asthma were diagnosed by specialists. FLG-SNVs were identified by Sanger sequencing of entire exons through long-range PCR. Allergic sensitization to a specific allergen was evaluated by multiple allergen simultaneous test. Serologic parameters such as serum eosinophil cationic protein (ECP) and eosinophil derived neurotoxin (EDN) were measured. RESULTS: A total of seventy-three SNVs and 4 LOF mutations were successfully genotyped. rs71626704 and rs76413899 were significantly associated with a history of asthma and cheilitis (P = 0.002 and P = 0.033, respectively), however, the associations were not found statistically significant after adjustment by multiple comparisons. In addition, we detected haplotype blocks which were correlated with non-specific hand or foot dermatitis and scalp scale. We identified FLG-SNVs which were associated with sensitization to environmental allergens; rs62623409 and rs71625199 (P = 0.038 and P = 0.008, respectively). Patients with FLG P478S TT and history of allergic rhinitis showed a higher EDN level, and among those patients, the ones with asthma showed a higher ECP level. CONCLUSION: This study revealed the association of FLG-SNVs with AD-associated minor clinical features. We firstly identified rs71625199 which was associated with higher environmental allergic sensitization. We also suggest that FLG P478S is a kind of disease modifier which affects serologic parameters such as EDN and ECP.
[Mh] MeSH terms primary: Dermatitis, Atopic/genetics
Genetic Variation
S100 Proteins/genetics
[Mh] MeSH terms secundary: Humans
Mutation
Phenotype
Young Adult
[Pt] Publication type:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Name of substance:0 (S100 Proteins); 0 (filaggrin-2 protein, human)
[Em] Entry month:1802
[Cu] Class update date: 180206
[Lr] Last revision date:180206
[Js] Journal subset:IM
[Da] Date of entry for processing:171228
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190077


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