Database : MEDLINE
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[PMID]: 29514062
[Au] Autor:Pan A; Lin X; Hemler E; Hu FB
[Ad] Address:Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health and State Key Laboratory of Environmental Health (incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, Ch
[Ti] Title:Diet and Cardiovascular Disease: Advances and Challenges in Population-Based Studies.
[So] Source:Cell Metab;27(3):489-496, 2018 Mar 06.
[Is] ISSN:1932-7420
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:In this Minireview, we provide an epidemiologist's perspective on the debate and recent advances in determining the relationship between diet and cardiovascular health. We conclude that, in order to reduce the global burden of cardiovascular disease, there should be a greater emphasis on improving overall diet quality and food sources of macronutrients, such as dietary fats and carbohydrates. In addition, building a strong evidence base through high-quality intervention and observational studies is crucial for effective policy changes, which can greatly improve the food environment and population health.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review

  2 / 28827 MEDLINE  
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[PMID]: 29335275
[Au] Autor:Linden AG; Li S; Choi HY; Fang F; Fukasawa M; Uyeda K; Hammer RE; Horton JD; Engelking LJ; Liang G
[Ad] Address:Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
[Ti] Title:Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice.
[So] Source:J Lipid Res;59(3):475-487, 2018 03.
[Is] ISSN:1539-7262
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Lipogenesis in liver is highest in the postprandial state; insulin activates SREBP-1c, which transcriptionally activates genes involved in FA synthesis, whereas glucose activates carbohydrate-responsive element-binding protein (ChREBP), which activates both glycolysis and FA synthesis. Whether SREBP-1c and ChREBP act independently of one another is unknown. Here, we characterized mice with liver-specific deletion of ChREBP ( mice). Hepatic ChREBP deficiency resulted in reduced mRNA levels of glycolytic and lipogenic enzymes, particularly in response to sucrose refeeding following fasting, a dietary regimen that elicits maximal lipogenesis. mRNA and protein levels of SREBP-1c, a master transcriptional regulator of lipogenesis, were also reduced in livers. Adeno-associated virus-mediated restoration of nuclear SREBP-1c in mice normalized expression of a subset of lipogenic genes, while not affecting glycolytic genes. Conversely, ChREBP overexpression alone failed to support expression of lipogenic genes in the livers of mice lacking active SREBPs as a result of Scap deficiency. Together, these data show that SREBP-1c and ChREBP are both required for coordinated induction of glycolytic and lipogenic mRNAs. Whereas SREBP-1c mediates insulin's induction of lipogenic genes, ChREBP mediates glucose's induction of both glycolytic and lipogenic genes. These overlapping, but distinct, actions ensure that the liver synthesizes FAs only when insulin and carbohydrates are both present.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1801
[Cu] Class update date: 180311
[Lr] Last revision date:180311
[St] Status:In-Data-Review
[do] DOI:10.1194/jlr.M081836

  3 / 28827 MEDLINE  
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[PMID]: 29524001
[Au] Autor:Liu S; van der Schouw YT; Soedamah-Muthu SS; Spijkerman AMW; Sluijs I
[Ad] Address:Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, STR6.131, 3508 GA, Utrecht, The Netherlands.
[Ti] Title:Intake of dietary saturated fatty acids and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort: associations by types, sources of fatty acids and substitution by macronutrients.
[So] Source:Eur J Nutr;, 2018 Mar 09.
[Is] ISSN:1436-6215
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:PURPOSE: The association between dietary saturated fatty acids (SFA) intake and type 2 diabetes (T2D) remains unclear. This study aimed at investigating the association between SFA intake and T2D risk based on (1) individual SFA (differing in carbon chain length), (2) food sources of SFA and (3) the substituting macronutrients. METHODS: 37,421 participants from the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) cohort were included in this study. Baseline dietary intake was assessed by a validated food frequency questionnaire. T2D risks were estimated by Cox regression models adjusted for non-dietary and dietary covariates. RESULTS: 893 incident T2D cases were documented during 10.1-year follow-up. We observed no association between total SFA and T2D risk. Marginally inverse associations were found for lauric acid (HR per 1 SD of energy%, 95% CI 0.92, 0.85-0.99), myristic acid (0.89, 0.79-0.99), margaric acid (0.84, 0.73-0.97), odd-chain SFA (pentadecylic plus margaric acids; 0.88, 0.79-0.99), and cheese derived SFA (0.90, 0.83-0.98). Soft and liquid fats derived SFA was found related to higher T2D risk (1.08, 1.01-1.17). When substituting SFA by proteins, carbohydrates and polyunsaturated fatty acids, significantly higher risks of T2D were observed (HRs per 1 energy% ranging from 1.05 to 1.15). CONCLUSION: In this Dutch population, total SFA does not relate to T2D risk. Rather, the association may depend on the types and food sources of SFA. Cheese-derived SFA and individual SFA that are commonly found in cheese, were significantly related to lower T2D risks. We cannot exclude the higher T2D risks found for soft and liquid fats derived SFA and for substituting SFA with other macronutrients are influenced by residual confounding by trans fatty acids or limited intake variation in polyunsaturated fatty acids and vegetable protein.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180310
[Lr] Last revision date:180310
[St] Status:Publisher
[do] DOI:10.1007/s00394-018-1630-4

  4 / 28827 MEDLINE  
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[PMID]: 29522789
[Au] Autor:Sainsbury E; Kizirian NV; Partridge SR; Gill T; Colagiuri S; Gibson AA
[Ad] Address:The University of Sydney, The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, Charles Perkins Centre, NSW, Australia, 2006. Electronic address: emma.sainsbury@sydney.edu.au.
[Ti] Title:Effect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis.
[So] Source:Diabetes Res Clin Pract;, 2018 Mar 06.
[Is] ISSN:1872-8227
[Cp] Country of publication:Ireland
[La] Language:eng
[Ab] Abstract:Nutrition therapy is considered a key component of diabetes management, yet evidence around the ideal macronutrient composition of the diet remains inconclusive. A systematic review and meta-analysis was performed to assess the effects of carbohydrate-restricted diets (≤ 45% of total energy) compared to high carbohydrate diets (> 45% of total energy) on glycemic control in adults with diabetes mellitus. Six databases were searched for articles published between January 1980 and August 2016. Primary outcome was between-group difference in HbA1c change. Individual effect sizes were standardized, and a meta-analysis performed to calculate pooled effect size using random effects. 25 RCTs involving 2412 participants were included. Carbohydrate-restricted diets, in particular those that restrict carbohydrate to < 26% of total energy, produced greater reductions in HbA1c at 3 months (WMD -0.47%, 95% CI: -0.71, -0.23) and 6 months (WMD -0.36%, 95% CI: -0.62, -0.09), with no significant difference at 12 or 24 months. There was no difference between moderately restricted (26-45% of total energy) and high carbohydrate diets at any time point. Although there are issues with the quality of the evidence, this review suggests that carbohydrate-restricted diets could be offered to people living with diabetes as part of an individualised management plan.
[Pt] Publication type:JOURNAL ARTICLE; REVIEW
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher

  5 / 28827 MEDLINE  
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[PMID]: 29522694
[Au] Autor:Monk JM; Wu W; McGillis LH; Wellings HR; Hutchinson AL; Liddle DM; Graf D; Robinson LE; Power KA
[Ad] Address:University of Guelph, Guelph, Ontario, Canada.
[Ti] Title:Chickpea supplementation prior to colitis onset reduces inflammation in dextran sodium sulfate-treated C57Bl/6 male mice.
[So] Source:Appl Physiol Nutr Metab;, 2018 Mar 09.
[Is] ISSN:1715-5320
[Cp] Country of publication:Canada
[La] Language:eng
[Ab] Abstract:The potential for a chickpea supplemented diet (rich in fermentable non-digestible carbohydrates and phenolic compounds) to modify the colonic microenvironment and attenuate the severity of acute colonic inflammation was investigated. C57Bl/6 male mice were fed a control basal diet (BD) or BD supplemented with 20% cooked chickpea flour for 3 weeks prior to acute colitis onset induced by 7-day exposure to dextran sodium sulfate (DSS, 2% w/v in drinking water) and colon and serum levels of inflammatory mediators were assessed. Despite an equal degree of DSS-induced epithelial barrier histological damage and clinical symptoms between dietary groups, biomarkers of the ensuing inflammatory response were attenuated by CK pre-feeding including reduced colon tissue activation of NFκB and inflammatory cytokine production (TNFα and IL-18). Additionally, colon protein expression of anti-inflammatory (IL-10) and epithelial repair (IL-22 and IL-27) cytokines were increased by CK pre-feeding. Furthermore, during acute colitis CK pre-feeding increased markers of enhanced colonic function including mRNA expression of Relmß and IgA. Collectively, CK pre-feeding modulated the baseline function of the colonic microenvironment, whereby upon induction of acute colitis, the severity of the inflammatory response was attenuated.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[St] Status:Publisher
[do] DOI:10.1139/apnm-2017-0689

  6 / 28827 MEDLINE  
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[PMID]: 28467207
[Au] Autor:Moon S
[Ad] Address:a Department of Nursing , College of Medicine, University of Ulsan , Ulsan , South Korea.
[Ti] Title:Unhealthy Lifestyle Behaviors in Korean People with Metabolic Syndrome.
[So] Source:J Community Health Nurs;34(2):69-79, 2017 Apr-Jun.
[Is] ISSN:1532-7655
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:This study identified factors associated with unhealthy lifestyle behaviors in people with metabolic syndrome in South Korea. The sample consisted of 1,207 subjects with metabolic syndrome from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014. High-risk alcohol consumption, smoking, aerobic physical activity, leisure physical activity, excessive carbohydrate intake, and fat intake were measured. A secondary data analysis was performed using chi-square tests and logistic regression. Gender was associated with all unhealthy behaviors. The number of metabolic syndrome components, a poor perceived health status, and attempts to control weight were associated with physical inactivity. Those findings may be helpful to develop a tailored lifestyle modification programs for people with metabolic syndrome.
[Mh] MeSH terms primary: Health Behavior
Metabolic Syndrome/psychology
[Mh] MeSH terms secundary: Adult
Aged
Alcohol Drinking/adverse effects
Alcohol Drinking/epidemiology
Chi-Square Distribution
Cross-Sectional Studies
Dietary Carbohydrates/administration & dosage
Dietary Carbohydrates/adverse effects
Dietary Fats/administration & dosage
Dietary Fats/adverse effects
Exercise
Female
Humans
Life Style
Logistic Models
Male
Middle Aged
Nutrition Surveys
Republic of Korea/epidemiology
Sex Factors
Smoking/adverse effects
Smoking/epidemiology
Young Adult
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dietary Carbohydrates); 0 (Dietary Fats)
[Em] Entry month:1803
[Cu] Class update date: 180309
[Lr] Last revision date:180309
[Js] Journal subset:IM; N
[Da] Date of entry for processing:170504
[St] Status:MEDLINE
[do] DOI:10.1080/07370016.2017.1304145

  7 / 28827 MEDLINE  
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[PMID]: 29385488
[Au] Autor:Navarro DMDL; Bruininx EMAM; de Jong L; Stein HH
[Ad] Address:Department of Animal Sciences, University of Illinois, Urbana, IL.
[Ti] Title:Analysis for low-molecular-weight carbohydrates is needed to account for all energy-contributing nutrients in some feed ingredients, but physical characteristics do not predict in vitro digestibility of dry matter.
[So] Source:J Anim Sci;96(2):532-544, 2018 Mar 06.
[Is] ISSN:1525-3163
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:An experiment was conducted to quantify nutrient and fiber fractions of feed ingredients and to determine in vitro apparent ileal digestibility (IVAID) and in vitro apparent total tract digestibility (IVATTD) of DM and OM in each ingredient. Ten ingredients that vary in fiber concentration and composition were used: corn, wheat, soybean meal (SBM), canola meal, distillers dried grains with solubles (DDGS), corn germ meal, copra expellers, sugar beet pulp (SBP), synthetic cellulose (SF), and pectin. Correlations between chemical and physical characteristics of ingredients and IVAID and IVATTD of DM and OM were determined. The physical characteristics measured included bulk density, water-binding capacity (WBC), swelling, and viscosity. The analyzed GE was compared with values for GE calculated from all energy-contributing components. Results indicated that the analyzed chemical composition of most ingredients added to 100% or greater, except for DDGS, SBP, and SF, where nutrients added to only 94.29%, 88.90%, and 96.09%, respectively. The difference between the sum of the calculated GE of the analyzed components and the analyzed GE of the ingredients ranged from -2.25 MJ/kg in DDGS to 1.74 MJ/kg in pectin. No correlation was observed between swelling, WBC, or viscosity and IVAID or IVATTD of DM or OM. The concentration of insoluble dietary fiber (IDF) and total dietary fiber (TDF) was negatively correlated (P < 0.05) with IVAID and IVATTD of DM and OM. There was a tendency for NDF (r = -0.60) and ADF (r = -0.61) to be negatively correlated (P < 0.10) with IVAID of DM. However, no correlation was observed between the concentration of CP, GE, acid-hydrolyzed ether extract, lignin, or soluble dietary fiber and IVAID and IVATTD of DM and OM. The stronger correlations between IDF, TDF, and insoluble non-starch polysaccharides and IVAID and IVATTD of DM and OM than between ADF and NDF and IVAID and IVATTD of DM and OM indicate that the concentration of TDF in feed ingredients is a better predictor of the digestibility of DM and OM than values for NDF and ADF. In conclusion, the calculated GE of some feed ingredients was in agreement with the analyzed GE, which gives confidence that energy-contributing components were accounted for, but for DDGS and SBP, it was not possible to account for all analyzed GE. Concentrations of IDF and TDF, but not the physical characteristics of feed ingredients, may be used to estimate IVAID and IVATTD of DM and OM in feed ingredients.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.1093/jas/sky010

  8 / 28827 MEDLINE  
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[PMID]: 29385466
[Au] Autor:Brake DW; Swanson KC
[Ad] Address:Department of Animal Science, South Dakota State University, Brookings, SD.
[Ti] Title:RUMINANT NUTRITION SYMPOSIUM: Effects of postruminal flows of protein and amino acids on small intestinal starch digestion in beef cattle.
[So] Source:J Anim Sci;96(2):739-750, 2018 Mar 06.
[Is] ISSN:1525-3163
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Many nutritionists adopt feeding strategies designed to increase ruminal starch fermentation because ruminal capacity for starch degradation often exceeds amounts of starch able to be digested in the small intestine of cattle. However, increases in fermentable energy supply are positively correlated with increased instances of metabolic disorders and reductions in DMI, and energy derived by cattle subsequent to fermentation is less than that derived when glucose is intestinally absorbed. Small intestinal starch digestion (SISD) appears to be limited by α-glycohydrolase secretions and a precise understanding of digestion of carbohydrates in the small intestine remains equivocal. Interestingly, small intestinal α-glycohydrolase secretions are responsive to luminal appearance of milk-specific protein (i.e., casein) in the small intestine of cattle, and SISD is increased by greater postruminal flows of individual AA (i.e., Glu). Greater flows of casein and Glu appear to augment SISD, but by apparently different mechanisms. Greater small intestinal absorption of glucose has been associated with increased omental fat accretion even though SISD can increase NE from starch by more than 42% compared to ruminal starch degradation. Nonetheless, in vitro data suggest that greater glucogenicity of diets can allow for greater intramuscular fat accretion, and if greater small intestinal absorption of glucose does not mitigate hepatic gluconeogenesis then increases in SISD may provide opportunity to increase synthesis of intramuscular fat. If duodenal metabolizable AA flow can be altered to allow for improved SISD in cattle, then diet modification may allow for large improvements in feed efficiency and beef quality. Few data are available on direct effects of increases in SISD in response to greater casein or metabolizable Glu flow. An improved understanding of effects of increased SISD in response to greater postruminal flow of Glu and casein on improvements in NE and fates of luminally assimilated glucose could allow for increased efficiency of energy use from corn and improvements in conversion of corn grain to beef. New knowledge related to effects of greater postruminal flow of Glu and casein on starch utilization by cattle will allow nutritionists to more correctly match dietary nutrients to cattle requirements, thereby allowing large improvements in nutrient utilization and efficiency of gain among cattle fed starch-based diets.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1802
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[St] Status:In-Process
[do] DOI:10.1093/jas/skx058

  9 / 28827 MEDLINE  
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[PMID]: 29280369
[Au] Autor:Barbarska O; Zielinska M; Pawlus B; Wesolowska A
[Ad] Address:Laboratory of Human Milk and Lactation Research, Regional Human Milk Bank in Holy Family Hospital, Department of Neonatology, Medical University of Warsaw, Poland
[Ti] Title:Characteristics of the regional human milk bank in Poland - donors, recipients and nutritional value of human milk
[So] Source:Rocz Panstw Zakl Hig;68(4):395-400, 2017.
[Is] ISSN:0035-7715
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Background: In case of shortage of breast milk despite proper lactation care or the poor state of the mother's health, breast milk from human milk bank is recommended for feeding preterm infants Objective: This study retrospectively evaluated the first year of the operation of the Regional Human Milk Bank Material and methods: Data concerning donors was collected in the human milk bank during the cooperation. The clinical characteristics of the recipients was made on the basis of medical documentation from the Holy Family Hospital in Warsaw, Poland. Analysis of nutritional value was performed with the human milk analyzer (MIRIS AB) Results: In the first year of activity, 45 voluntary donors established cooperation, donating from 650 to 32030 ml of human milk. The content of nutrients in milk provided by donors was variable - protein 0.4-1.5 g / 100 ml, fat 1.1-7.4 g / 100 ml, carbohydrates 6.3-7.9 g / 100 ml. The average length of using donated human milk was 4 days and the average volume of milk for one infant was 282 ml Conclusions: The donor profiles have a significant impact on the milk composition form HMB. The nutritional value can be improved by recruitment donors from mothers that gave birth prematurely and by beginning donation at earlier stages of lactation as soon as lactation is stabilized. In case of shortage of mothers own milk the immediate implementation of donors milk as a short-term support can significantly reduce the food intolerance incidence in the group of prematurely born infants
[Mh] MeSH terms primary: Milk Banks
Milk, Human/chemistry
Nutritive Value
[Mh] MeSH terms secundary: Dietary Carbohydrates/analysis
Dietary Fats/analysis
Dietary Proteins/analysis
Female
Humans
Infant Nutritional Physiological Phenomena
Infant, Newborn
Poland
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Dietary Carbohydrates); 0 (Dietary Fats); 0 (Dietary Proteins)
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:171228
[St] Status:MEDLINE

  10 / 28827 MEDLINE  
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[PMID]: 29265787
[Au] Autor:Bzikowska A; Czerwonogrodzka-Senczyna A; Riahi A; Weker H
[Ad] Address:Warsaw Medical University, Faculty of Health Science, Department of Clinical Dietetics, Warsaw, Poland
[Ti] Title:Nutritional value of daily food rations of overweight and normal weight pregnant women
[So] Source:Rocz Panstw Zakl Hig;68(4):375-379, 2017.
[Is] ISSN:0035-7715
[Cp] Country of publication:Poland
[La] Language:eng
[Ab] Abstract:Background: Adequate nutrition and nutritional status during pregnancy are essential for mother's health and foetus development. Due to increased demands, pregnant women are vulnerable to inadequate nutritional status and paradoxically it may also affect overweight women Objective: The aim of the study was to evaluate energy and nutrients intake in the group of pregnant women in relation to nutritional standards and pre-pregnancy BMI Material and methods: The study included 90 women, during the third trimester of pregnancy, recruited from Warsaw antenatal classes. The anthropometric data gathered in the research were used to calculate BMI value before pregnancy. Pre-pregnancy BMI was categorised as: normal weight (BMI=18.5-24.9 kg/m2, n=47) and overweight (BMI ≥25.0 kg/m2, n=43). The assessment of women's nutrition was based on 3-days dietary record. Due to heterogeneous variances, differences between groups were assessed using Mann Whitney U test, p<0.05 was considered as significant Results: The mean intake of energy, protein, fat and carbohydrates in the overweight women were significantly higher than in healthy weight women (p<0.05). Most of the healthy weight women did not reach EAR standard for vitamin D (79.5%), whereas in overweight group it was 41.3% Conclusions: Despite the fact that intakes of energy and all nutrients were higher in overweight women than in normal weight ones, we observed that women in both groups had risk of insufficient supply of energy, iodine, potassium and vitamin D. For this reason, accurate nutritional assessment should be an integral part of obstetric care
[Mh] MeSH terms primary: Diet
Nutritional Status
Nutritive Value
Pregnancy Trimester, Third
Prenatal Nutritional Physiological Phenomena
[Mh] MeSH terms secundary: Body Mass Index
Diet Records
Female
Humans
Ideal Body Weight
Nutrition Assessment
Overweight
Poland
Pregnancy
Prenatal Care
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1803
[Cu] Class update date: 180308
[Lr] Last revision date:180308
[Js] Journal subset:IM
[Da] Date of entry for processing:171222
[St] Status:MEDLINE


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