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[PMID]: 29096969
[Au] Autor:Golpe R; Suárez-Valor M; Veres-Racamonde A; Cano-Jiménez E; Martín-Robles I; Sanjuán-López P; Pérez-de-Llano L
[Ad] Address:Servicio de Neumología, Hospital Universitario Lucus Augusti, Lugo, España. Electronic address: rafael.golpe.gomez@sergas.es.
[Ti] Title:Pacientes octogenarios con enfermedad pulmonar obstructiva crónica: características y utilidad de los índices pronósticos. Octogenarian patients with chronic obstructive pulmonary disease: Characteristics and usefulness of prognostic indexes.
[So] Source:Med Clin (Barc);, 2017 Oct 30.
[Is] ISSN:1578-8989
[Cp] Country of publication:Spain
[La] Language:eng; spa
[Ab] Abstract:BACKGROUND AND OBJECTIVE: Most studies on chronic obstructive pulmonary disease (COPD) exclude octogenarian patients. Therefore, the disease is not well characterized in this age group. The objective of this study is to analyze the clinical characteristics of octogenarian patients with COPD and the usefulness of the prognostic indexes used most frequently in this age group. PATIENTS AND METHOD: Retrospective study of consecutive patients seen at a clinic between 2009 and 2017. The following variables were analyzed: lung function parameters, distribution of clinical phenotypes, income history, mortality, comorbidities and usefulness of the Charlson, BODEX, COTE and CODEX indexes to predict mortality. RESULTS: The sample comprised 698 patients, 82 aged (11.7%)≥80 years old. Mean follow-up time was 47.9±21.8 months. In octogenarian patients, the severity of the COPD, assessed by means of the FEV % or BODEX index, was similar to that of younger patients, but dyspnea was worse in the elderly group. In these patients, the chronic bronchitis and frequent exacerbator phenotypes were the most frequent, whilst the emphysema phenotype was the least common. Octogenarians had a greater prevalence of cardiovascular comorbidities and renal diseases. Moreover, hospital admissions were more frequent and mortality was higher in these elderly patients. Most prognostic indexes were useful in predicting mortality in elderly patients. CODEX was the most useful index to predict mortality, both in octogenarian and younger patients. CONCLUSION: Octogenarian patients with COPD have differential characteristics which could imply the need for different therapeutic approaches. Prognostic indexes are useful for predicting mortality in this population.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher

  2 / 27614 MEDLINE  
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[PMID]: 29089753
[Au] Autor:Tuleta I; Farrag T; Busse L; Pizarro C; Schaefer C; Pingel S; Nickenig G; Skowasch D; Schahab N
[Ad] Address:Department of Internal Medicine II - Cardiology, Pulmonology and Angiology, University of Bonn, Bonn, Germany.
[Ti] Title:High prevalence of COPD in atherosclerosis patients.
[So] Source:Int J Chron Obstruct Pulmon Dis;12:3047-3053, 2017.
[Is] ISSN:1178-2005
[Cp] Country of publication:New Zealand
[La] Language:eng
[Ab] Abstract:Atherosclerosis and COPD are both systemic inflammatory diseases that may influence each other. The aim of the present study was to determine the prevalence of COPD in patients with cerebral and/or peripheral artery disease and to assess factors associated with the presence of COPD. Following the diagnosis of cerebral and/or peripheral artery disease by means of duplex sonography, 166 consecutive patients underwent body plethysmography with capillary blood gas analysis. Thereafter, blood tests with determination of different parameters such as lipid profile, inflammatory and coagulation markers were conducted in remaining 136 patients who fulfilled inclusion criteria of the study. Thirty-six out of 136 patients suffered from COPD, mostly in early stages of the disease. Residual volume indicating emphysema was increased (162.9%±55.9% vs 124.5%±37.0%, <0.05) and diffusion capacity was decreased (55.1%±19.5% vs 75.3%±18.6%, <0.05) in COPD patients vs non-COPD group. In capillary blood gas analysis, COPD patients had lower partial pressure of oxygen (70.9±11.5 vs 75.2±11.0 mmHg, <0.05) and higher partial pressure of carbon dioxide (36.8±7.5 vs 34.4±4.4 mmHg, <0.05) compared with non-COPD individuals. Presence of COPD was associated with predominance of diabetes mellitus, interleukin-8-related systemic neutrophilic inflammation and anemia. In conclusion, COPD is highly prevalent in patients with atherosclerotic artery disease.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:In-Process
[do] DOI:10.2147/COPD.S141988

  3 / 27614 MEDLINE  
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[PMID]: 29089699
[Au] Autor:Hemmati H; Forozeshfard M; Hosseinzadeh B; Hemmati S; Mirmohammadkhani M; Bandari R
[Ad] Address:Department of Surgery, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran.
[Ti] Title:Tracheostomy in Patients Who Need Mechanical Ventilation: Early or Late? Surgical or Percutaneous? A Prospective Study in Iran.
[So] Source:Indian J Surg;79(5):406-411, 2017 Oct.
[Is] ISSN:0972-2068
[Cp] Country of publication:India
[La] Language:eng
[Ab] Abstract:Tracheostomy can be performed surgically or by percutaneous (percutaneous dilatory tracheostomy, PDT) methods, and it may be used early or late. In a 3-month follow-up, all patients who underwent tracheostomy in Semnan in 2013 were evaluated for complications of tracheostomy considering the method used and the timing of operation. A total of 55 patients underwent tracheostomy (26 cases surgery, 29 cases PDT, 30 cases early, and 25 cases late based on 14 days reference). The mean durations of operation were 19.19 ± 5.78 min in the surgery method and 4.7 ± 2.42 min in the PDT method ( < 0.001). The mean durations of the need for ventilator after the tracheostomy were 10.7 ± 9.25 and 18.6 ± 14.39 days in early and late tracheostomy, respectively ( = 0.024). The mean intensive care unit (ICU) stay were 12.70 ± 10.24 and 23.44 ± 18.49 days ( = 0.014) and the mean hospital stay were 16.04 ± 10.88 and 23.48 ± 18.47 days, respectively ( = 0.100). Short-term complications were observed in six cases (10.09 %) in the surgery group, including emphysema (two), bleeding (two), wound infection (one), and clot formation inside the tube (one). Only one complication (bleeding) occurred in one case in the PDT group. After 3 months, 21 patients survived. Compared with surgery, the most important advantage of the PDT method was its shorter duration of surgery. Nearly half of the patients underwent tracheostomy late, while the majority of the patients in the late group were referred from internal ICU. No major and minor complications were noted during the procedure, as well as no tracheostomy-related deaths were observed. Early tracheostomy was shown to be superior to late, reducing the time of mechanical ventilation and ICU or hospital stay.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:In-Data-Review
[do] DOI:10.1007/s12262-016-1497-7

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[PMID]: 29074811
[Au] Autor:Oelsner EC; Smith BM; Hoffman EA; Folsom AR; Kawut SM; Kaufman JD; Manichaikul A; Lederer DJ; Schwartz JE; Watson KE; Enright PL; Austin JHM; Lima JAC; Shea SJ; Barr RG
[Ad] Address:Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, New York, USA.
[Ti] Title:Associations between emphysema-like lung on CT and incident airflow limitation: a general population-based cohort study.
[So] Source:Thorax;, 2017 Oct 26.
[Is] ISSN:1468-3296
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:Emphysema on CT is associated with accelerated lung function decline in heavy smokers and patients with COPD; however, in the general population, it is not known whether greater emphysema-like lung on CT is associated with incident COPD. We used data from 2045 adult participants without initial prebronchodilator airflow limitation, classified by FEV /FVC<0.70, in the Multi-Ethnic Study of Atherosclerosis. Emphysema-like lung on baseline cardiac CT, defined as per cent low attenuation areas >upper limit of normal, was associated with increased odds of incident airflow limitation at 5-year follow-up on both prebronchodilator (adjusted OR 2.62, 95% CI 1.47 to 4.67) and postbronchodilator (adjusted OR 4.38, 95% CI 1.63 to 11.74) spirometry, independent of smoking history. These results support investigation into whether emphysema-like lung could be informative for COPD risk stratification.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:Publisher

  5 / 27614 MEDLINE  
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[PMID]: 29065892
[Au] Autor:Bradford E; Jacobson S; Varasteh J; Comellas AP; Woodruff P; O'Neal W; DeMeo DL; Li X; Kim V; Cho M; Castaldi PJ; Hersh C; Silverman EK; Crapo JD; Kechris K; Bowler RP
[Ad] Address:Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, 1400 Jackson St., K715, Denver, CO, 80206, USA.
[Ti] Title:The value of blood cytokines and chemokines in assessing COPD.
[So] Source:Respir Res;18(1):180, 2017 Oct 24.
[Is] ISSN:1465-993X
[Cp] Country of publication:England
[La] Language:eng
[Ab] Abstract:BACKGROUND: Blood biomarkers are increasingly used to stratify high risk chronic obstructive pulmonary disease (COPD) patients; however, there are fewer studies that have investigated multiple biomarkers and replicated in multiple large well-characterized cohorts of susceptible current and former smokers. METHODS: We used two MSD multiplex panels to measure 9 cytokines and chemokines in 2123 subjects from COPDGene and 1117 subjects from SPIROMICS. These biomarkers included: interleukin (IL)-2, IL-6, IL-8, IL-10, tumor necrosis factor (TNF)-α, interferon (IFN)-γ, eotaxin/CCL-11, eotaxin-3/CCL-26, and thymus and activation-regulated chemokine (TARC)/CCL-17. Regression models adjusted for clinical covariates were used to determine which biomarkers were associated with the following COPD phenotypes: airflow obstruction (forced expiratory flow at 1 s (FEV %) and FEV /forced vital capacity (FEV /FVC), chronic bronchitis, COPD exacerbations, and emphysema. Biomarker-genotype associations were assessed by genome-wide association of single nucleotide polymorphisms (SNPs). RESULTS: Eotaxin and IL-6 were strongly associated with airflow obstruction and accounted for 3-5% of the measurement variance on top of clinical variables. IL-6 was associated with progressive airflow obstruction over 5 years and both IL-6 and IL-8 were associated with progressive emphysema over 5 years. None of the biomarkers were consistently associated with chronic bronchitis or COPD exacerbations. We identified one novel SNP (rs9302690 SNP) that was associated with CCL17 plasma measurements. CONCLUSION: When assessing smoking related pulmonary disease, biomarkers of inflammation such as IL-2, IL-6, IL-8, and eotaxin may add additional modest predictive value on top of clinical variables alone. TRIAL REGISTRATION: COPDGene (ClinicalTrials.gov Identifier: NCT02445183 ). Subpopulations and Intermediate Outcomes Measures in COPD Study (SPIROMICS) ( ClinicalTrials.gov Identifier: NCT 01969344 ).
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1710
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[St] Status:In-Process
[do] DOI:10.1186/s12931-017-0662-2

  6 / 27614 MEDLINE  
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[PMID]: 29054230
[Au] Autor:King N; Ramesh SS; Essandoh M; Merritt RE
[Ad] Address:Department of Thoracic Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address: nakesha.king@osumc.edu.
[Ti] Title:Near Complete Obliteration of the Left Hemithorax by Congenital Lobar Emphysema in an Adult.
[So] Source:Ann Thorac Surg;104(5):e367-e369, 2017 Nov.
[Is] ISSN:1552-6259
[Cp] Country of publication:Netherlands
[La] Language:eng
[Ab] Abstract:Congenital lobar emphysema is a rare pulmonary malformation typically diagnosed during infancy and is characterized by bullous disease. A 28-year-old woman, who presented with 1 week of progressive dyspnea and chest pain, was found to have left hemithoracic lung hyperinflation with perfusion deficit upon radiographic evaluation. Bullous disease was found intraoperatively to originate from 1 lower lobe segment. Normal parenchymal lung expansion occurred following resection of the affected segment. Therefore, we present a rare case of congenital lobar emphysema resulting in near-complete occupancy of the left hemithorax and diagnosed in a previously asymptomatic adult without history of predisposing factors.
[Mh] MeSH terms primary: Pneumothorax/diagnostic imaging
Pulmonary Emphysema/congenital
Thoracic Surgery, Video-Assisted/methods
[Mh] MeSH terms secundary: Adult
Bronchoscopy/methods
Chest Pain/diagnosis
Chest Pain/etiology
Disease Progression
Dyspnea/diagnosis
Dyspnea/etiology
Emergency Service, Hospital
Female
Follow-Up Studies
Humans
Pneumothorax/etiology
Pneumothorax/surgery
Positron-Emission Tomography/methods
Pulmonary Emphysema/complications
Pulmonary Emphysema/diagnostic imaging
Pulmonary Emphysema/surgery
Radiography, Thoracic/methods
Rare Diseases
Risk Assessment
Severity of Illness Index
Tomography, X-Ray Computed/methods
Treatment Outcome
[Pt] Publication type:CASE REPORTS; JOURNAL ARTICLE
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:AIM; IM
[Da] Date of entry for processing:171021
[St] Status:MEDLINE

  7 / 27614 MEDLINE  
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[PMID]: 28760516
[Au] Autor:Saadi A; Ayed H; Karray O; Kerkeni W; Bouzouita A; Cherif M; Ben Slama R; Derouiche A; Chebil M
[Ad] Address:Urology department, Charles-Nicolle hospital, university of Tunis El Manar, boulevard 9-Avril-1938, 1006 Tunis, Tunisie. Electronic address: dr.saadi.ahmed@gmail.com.
[Ti] Title:Complication rare de la transplantation rénale : la pyélonéphrite emphysémateuse. [Rare complication of renal transplantation: Emphysematous pyelonephritis].
[So] Source:Nephrol Ther;13(6):479-481, 2017 Nov.
[Is] ISSN:1872-9177
[Cp] Country of publication:France
[La] Language:fre
[Ab] Abstract:Emphysematous pyelonephritis is a necrotizing infection of the renal parenchyma and peri-renal tissues, characterized by the presence of air within the parenchyma of the urinary tract and peri-renal space. This is a severe complication, which involves the functional prognosis of the kidney and the patient's prognosis. The emphysematous pyelonephritis is a rare complication of renal transplantation. Its gravity is linked particularly to the fragility of immunosuppressed patients. The authors report the case of an emphysematous pyelonephritis having occurred 9 months after transplantation in a patient 58 years. The evolving risks and therapeutic modalities will be outlined and discussed.
[Pt] Publication type:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Entry month:1708
[Cu] Class update date: 171103
[Lr] Last revision date:171103
[St] Status:In-Process

  8 / 27614 MEDLINE  
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[PMID]: 28608438
[Au] Autor:van de Bool C; Rutten EPA; van Helvoort A; Franssen FME; Wouters EFM; Schols AMWJ
[Ad] Address:Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
[Ti] Title:A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD.
[So] Source:J Cachexia Sarcopenia Muscle;8(5):748-758, 2017 Oct.
[Is] ISSN:2190-6009
[Cp] Country of publication:Germany
[La] Language:eng
[Ab] Abstract:BACKGROUND: Evidence regarding the efficacy of nutritional supplementation to enhance exercise training responses in COPD patients with low muscle mass is limited. The objective was to study if nutritional supplementation targeting muscle derangements enhances outcome of exercise training in COPD patients with low muscle mass. METHODS: Eighty-one COPD patients with low muscle mass, admitted to out-patient pulmonary rehabilitation, randomly received oral nutritional supplementation, enriched with leucine, vitamin D, and omega-3 fatty acids (NUTRITION) or PLACEBO as adjunct to 4 months supervised high intensity exercise training. RESULTS: The study population (51% males, aged 43-80) showed moderate airflow limitation, low diffusion capacity, normal protein intake, low plasma vitamin D, and docosahexaenoic acid. Intention-to-treat analysis revealed significant differences after 4 months favouring NUTRITION for body mass (mean difference ± SEM) (+1.5 ± 0.6 kg, P = 0.01), plasma vitamin D (+24%, P = 0.004), eicosapentaenoic acid (+91%,P < 0.001), docosahexaenoic acid (+31%, P < 0.001), and steps/day (+24%, P = 0.048). After 4 months, both groups improved skeletal muscle mass (+0.4 ± 0.1 kg, P < 0.001), quadriceps muscle strength (+12.3 ± 2.3 Nm,P < 0.001), and cycle endurance time (+191.4 ± 34.3 s, P < 0.001). Inspiratory muscle strength only improved in NUTRITION (+0.5 ± 0.1 kPa, P = 0.001) and steps/day declined in PLACEBO (-18%,P = 0.005). CONCLUSIONS: High intensity exercise training is effective in improving lower limb muscle strength and exercise performance in COPD patients with low muscle mass and moderate airflow obstruction. Specific nutritional supplementation had additional effects on nutritional status, inspiratory muscle strength, and physical activity compared with placebo.
[Pt] Publication type:JOURNAL ARTICLE
[Em] Entry month:1706
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[St] Status:In-Process
[do] DOI:10.1002/jcsm.12219

  9 / 27614 MEDLINE  
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[PMID]: 28459279
[Au] Autor:Obeidat M; Nie Y; Fishbane N; Li X; Bossé Y; Joubert P; Nickle DC; Hao K; Postma DS; Timens W; Sze MA; Shannon CP; Hollander Z; Ng RT; McManus B; Miller BE; Rennard S; Spira A; Hackett TL; Lam W; Lam S; Faner R; Agusti A; Hogg JC; Sin DD; Paré PD
[Ad] Address:1 The University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
[Ti] Title:Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers.
[So] Source:Am J Respir Cell Mol Biol;57(4):411-418, 2017 Oct.
[Is] ISSN:1535-4989
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:Chronic obstructive pulmonary disease is the third leading cause of death worldwide. Gene expression profiling across multiple regions of the same lung identified genes significantly related to emphysema. We sought to determine whether the lung and epithelial expression of 127 emphysema-related genes was also related to lung function in independent cohorts, and whether any of these genes could be used as biomarkers in the peripheral blood of patients with chronic obstructive pulmonary disease. To that end, we examined whether the expression levels of these genes were under genetic control in lung tissue (n = 1,111). We then determined whether the mRNA levels of these genes in lung tissue (n = 727), small airway epithelial cells (n = 238), and peripheral blood (n = 620) were significantly related to lung function measurements. The expression of 63 of the 127 genes (50%) was under genetic control in lung tissue. The lung and epithelial mRNA expression of a subset of the emphysema-associated genes, including ASRGL1, LPHN2, and EDNRB, was strongly associated with lung function. In peripheral blood, the expression of 40 genes was significantly associated with lung function. Twenty-nine of these genes (73%) were also associated with lung function in lung tissue, but with the opposite direction of effect for 24 of the 29 genes, including those involved in hypoxia and B cell-related responses. The integrative genomics approach uncovered a significant overlap of emphysema genes associations with lung function between lung and blood with opposite directions between the two. These results support the use of peripheral blood to detect disease biomarkers.
[Mh] MeSH terms primary: Gene Expression Profiling
Gene Expression Regulation
Genomics
Lung/metabolism
Pulmonary Emphysema/metabolism
RNA, Messenger/biosynthesis
[Mh] MeSH terms secundary: B-Lymphocytes/metabolism
B-Lymphocytes/pathology
Biomarkers/metabolism
Cell Hypoxia
Female
Humans
Lung/pathology
Male
Pulmonary Emphysema/genetics
Pulmonary Emphysema/pathology
RNA, Messenger/genetics
[Pt] Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Name of substance:0 (Biomarkers); 0 (RNA, Messenger)
[Em] Entry month:1710
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:IM
[Da] Date of entry for processing:170501
[St] Status:MEDLINE
[do] DOI:10.1165/rcmb.2016-0284OC

  10 / 27614 MEDLINE  
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[PMID]: 28338535
[Au] Autor:Fintelmann FJ; Brinkmann JK; Jeck WR; Troschel FM; Digumarthy SR; Mino-Kenudson M; Shepard JO
[Ad] Address:Departments of *Radiology, Thoracic Imaging and Intervention †Pathology, Massachusetts General Hospital, Boston, MA.
[Ti] Title:Lung Cancers Associated With Cystic Airspaces: Natural History, Pathologic Correlation, and Mutational Analysis.
[So] Source:J Thorac Imaging;32(3):176-188, 2017 May.
[Is] ISSN:1536-0237
[Cp] Country of publication:United States
[La] Language:eng
[Ab] Abstract:PURPOSE: The aim of the study was to investigate the natural history of non-small cell lung cancers (NSCLCs) associated with cystic airspaces, including histopathology and molecular analysis. MATERIALS AND METHODS: A total of 34,801 computed tomographic (CT) scans of 2954 patients diagnosed with NSCLC between 2010 and 2015 were evaluated for association with a cystic airspace. Characteristics on serial CT, 18F-fludeoxyglucose positron emission tomography, and pathologic analysis were recorded. RESULTS: Cystic airspaces were associated with 1% of NSCLC cases (12 men and 18 women; median age, 66 y [range, 44 to 87 y]). Of the total number of patients, 97% had a smoking history. Twenty-four adenocarcinomas, 4 squamous cell carcinomas, and 2 poorly differentiated carcinomas were distributed throughout all lobes and were predominantly peripheral. Some cystic airspaces appeared in previously normal lungs, whereas others were preceded by subcentimeter nodules. Twenty of 30 cases demonstrated increased soft tissue due to wall thickening, increased loculations, enlargement and/or increased attenuation of a mural nodule, or replacement by a mass. 18F-fludeoxyglucose uptake was present if solid components measured >8 mm. Twenty of 30 patients demonstrated >1 cystic lesion or ground-glass nodule, lymphadenopathy, or evidence of prior lung resection. Pathologic analysis revealed that cystic airspaces correspond to a check-valve mechanism, adenocarcinoma superimposed on emphysema, cystification, and adenocarcinoma parasitizing a preexisting bulla. Fourteen of 26 tumors and 64% of adenocarcinomas tested positive for an alteration of KRAS with or without other alterations. CONCLUSIONS: Cystic airspaces preceded by nodules can evolve into NSCLCs. Wall thickening and/or mural nodularity may develop. Location in the periphery of the upper lobes, emphysema, additional cystic lesions or ground-glass nodules, lymphadenopathy, and prior lung cancer should further increase suspicion. Cystic airspaces on CT can be due to a check-valve mechanism obstructing the small airways, lepidic growth of adenocarcinoma in an area of emphysema, cystification of tumor due to degeneration, or adenocarcinoma growing along the wall of a preexisting bulla. KRAS mutations are the predominant genetic alterations.
[Mh] MeSH terms primary: Carcinoma, Non-Small-Cell Lung/diagnostic imaging
Carcinoma, Non-Small-Cell Lung/pathology
Lung Neoplasms/diagnostic imaging
Lung Neoplasms/pathology
Positron-Emission Tomography
Tomography, X-Ray Computed
[Mh] MeSH terms secundary: Adult
Aged
Aged, 80 and over
Female
Fluorodeoxyglucose F18
Humans
Lung/diagnostic imaging
Lung/pathology
Male
Middle Aged
Radiopharmaceuticals
[Pt] Publication type:JOURNAL ARTICLE
[Nm] Name of substance:0 (Radiopharmaceuticals); 0Z5B2CJX4D (Fluorodeoxyglucose F18)
[Em] Entry month:1711
[Cu] Class update date: 171102
[Lr] Last revision date:171102
[Js] Journal subset:IM
[Da] Date of entry for processing:170324
[St] Status:MEDLINE
[do] DOI:10.1097/RTI.0000000000000265


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